Vertical strabismus

H7_VERTISTRAB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.2
  • Hospital discharge: ICD-9 3783
  • Hospital discharge: ICD-8 37302
  • Cause of death: ICD-10 H50.2
  • Cause of death: ICD-9 3783
  • Cause of death: ICD-8 37302

2 out of 7 registries used, show all original rules.

1491

4. Check minimum number of events

None

1491

5. Include endpoints

None

1491

6. Filter based on genotype QC (FinnGen only)

1353

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus verticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9645 5200 4422
Only index persons 8778 4806 3972
Unadjusted period prevalence (%)
Whole population 0.14 0.15 0.12
Only index persons 0.17 0.18 0.15
Median age at first event (years)
Whole population 28.68 28.55 28.72
Only index persons 30.56 30.52 30.61

-FinnGen-

Key figures

All Female Male
Number of individuals 1353 823 530
Unadjusted period prevalence (%) 0.27 0.29 0.24
Median age at first event (years) 50.79 47.19 56.39

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1392
Matched controls
13920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.2
ICD-10 Finland
Vertical strabismus
12657.8
307.7
1129
*
H53.2
ICD-10 Finland
Diplopia
30.9
307.7
325
136
CEC00
NOMESCO Finland
Recession of extraocular muscle
2303.6
221.9
209
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
191.2
179
*
H50.52
ICD-10 Finland
Exophoria
76.9
186.1
100
14
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
61.5
165.0
92
16
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
163.9
154
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
158.4
149
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
157.3
148
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
1639.0
152.0
145
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.7
146.9
328
719
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
126.0
119
*
3503
FHL
Single muscle retroposition
+∞
109.9
104
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
46.5
98.3
58
13
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
90.6
86
*
H50.31
ICD-10 Finland
Intermittent exotropia
869.1
84.5
82
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
76.8
73
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
75.7
394
1533
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
27.8
74.8
51
19
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
74.7
71
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
7.3
73.8
113
167
XCK00
NOMESCO Finland
Perimetry
5.0
65.2
151
332
H50.8
ICD-10 Finland
Other specified strabismus
+∞
59.8
57
*
H50.9
ICD-10 Finland
Strabismus, unspecified
292.9
55.6
56
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
52.4
50
*
WX140
NOMESCO Finland
Parabulbar anesthesy
4.7
51.9
126
287
H50.30
ICD-10 Finland
Intermittent esotropy
526.8
51.8
51
*
H52.0
ICD-10 Finland
Hypermetropia
10.8
51.1
56
54
H53.0
ICD-10 Finland
Amblyopia ex anopsia
16.2
47.9
41
26
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
47.1
45
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
46.0
683
4207
H52.2
ICD-10 Finland
Astigmatism
11.5
45.1
47
42
H52.1
ICD-10 Finland
Myopia
7.7
42.2
60
81
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
40.8
39
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
39.8
38
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
34.9
176
652
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
34.5
33
*
H50.50
ICD-10 Finland
Alternating hyperphoria
66.8
34.2
39
6
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.6
33.4
217
917
H03BB01
ATC
carbimazole; oral
4.0
33.2
99
263
F95
ICPC
Strabismus
174.1
32.8
34
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
4.7
31.1
74
165
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
29.3
28
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
29.3
28
*
CE2W4
NOMESCO Finland
Eye movement mapping
58.0
29.2
34
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.9
28.8
489
3028
CS494
NOMESCO Finland
Other visual field testing
4.8
27.1
62
134
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.1
26.6
120
416
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.2
26.4
72
179
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
52.8
26.3
31
6
3504
FHL
Retroposition of two muscles
+∞
26.1
25
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
25.5
176
761
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
25.1
24
*
AA1AD
NOMESCO Finland
CT of head and brain
1.9
24.8
427
2632
H50.51
ICD-10 Finland
Esophoria
254.5
24.7
25
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
38.3
24.0
30
8
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
23.9
388
2340
ZXA00
NOMESCO Finland
Right side
1.9
22.2
380
2324
H05.2
ICD-10 Finland
Exophthalmic conditions
50.8
21.2
25
5
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
20.9
20
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
213.1
20.6
21
*
H062, E050,
ICD-10 Finland
42.3
20.5
25
6
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
20.3
205
1039
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
19.8
19
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
19.8
19
*
N07AA02
ATC
pyridostigmine; systemic
15.6
19.8
32
21
ZXA10
NOMESCO Finland
Bilateral
1.9
19.2
268
1524
Z3231
NOMESCO Finland
Registered nurse
1.8
19.1
391
2508
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
18.0
195
1013
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
17.9
150
703
WX402
NOMESCO Finland
General anaesthesia
1.8
17.8
340
2129
3501
FHL
Myotomy or tenotomy
+∞
17.7
17
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
17.7
17
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.5
17.4
25
34
ZXA05
NOMESCO Finland
Left side
1.8
17.2
334
2101
G70.0
ICD-10 Finland
Myasthenia gravis
19.6
16.9
25
13
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
16.7
16
*
3505
FHL
Single muscle resection
+∞
16.7
16
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
16.6
131
598
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
16.4
114
492
H25.0
ICD-10 Finland
Senile incipient cataract
2.6
16.4
96
382
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
30.4
16.1
21
7
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
5.4
15.6
31
59
108
Kela drug reimbursment
Myasthenia gravis
26.6
15.6
21
8
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
4.1
15.6
43
108
3507
FHL
Retroposition and resection
161.7
15.5
16
*
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.6
15.3
29
53
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
14.7
175
937
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
14.6
14
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
151.5
14.5
15
*
H26.4
ICD-10 Finland
After-cataract
2.1
14.4
136
669
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
14.1
113
519
H02.4
ICD-10 Finland
Ptosis of eyelid
3.2
13.9
54
171
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
13.8
135
673
R42
ICD-10 Finland
Dizziness and giddiness
1.7
13.7
319
2093
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
13.6
13
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.9
13.0
60
211
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
12.8
377
2618
3510
FHL
Cardiac surgery on three or more muscles
+∞
12.5
12
*
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
12.5
12
*
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
12.5
12
*
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
5.6
12.1
23
42
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.6
12.0
40
115
H03AA01
ATC
levothyroxine sodium; systemic
1.6
11.8
313
2113
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
11.6
114
568
WX002
NOMESCO Finland
Sedation and analgesia
1.7
11.4
255
1650
N99
ICPC
Neurological disease other
4.6
11.2
26
57
TAB00
NOMESCO Finland
Lumbar puncture
2.5
11.2
73
307
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.9
11.0
52
185
BAA60
NOMESCO Finland
Total thyroidectomy
3.1
10.8
45
149
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
10.5
65
266
Z2445
NOMESCO Finland
Psychologist
2.6
10.5
63
254
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
10.4
10
*
H50.59
ICD-10 Finland
Heterophor UNS
+∞
10.4
10
*
3508
FHL
Transposition or anteposition
+∞
10.4
10
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
10.4
10
*
H50
ICD-10 Finland
Other strabismus
+∞
10.4
10
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
8.9
10.3
21
24
S06.2
ICD-10 Finland
Diffuse brain injury
5.1
10.1
21
42
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.9
454
3437
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
26.2
9.8
13
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
9.7
423
3172
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.2
9.5
37
118
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.8
9.5
46
167
CAC20
NOMESCO Finland
Lateral decompression of orbit
100.7
9.4
10
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
9.4
206
1321
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
9.4
9
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
9.4
9
*
CEC85
NOMESCO Finland
Combined correction of cyclodeviation
+∞
9.4
9
*
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
12.4
9.4
16
13
104
Kela drug reimbursment
Thyroid insufficiency
2.0
9.3
95
481
WX400
NOMESCO Finland
Inhalation anesthesy
2.4
9.2
64
277
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.4
9.2
33
100
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.2
9.2
24
58
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.3
9.1
23
54
ZXD20
NOMESCO Finland
Day surgery
1.7
9.1
170
1044
CAC44
NOMESCO Finland
Combined decompression of orbit
36.9
9.0
11
*
ZXE00
NOMESCO Finland
One hour or less
1.4
9.0
493
3849
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.0
8.9
19
24
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
8.6
130
751
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
8.5
83
414
CA1AD
NOMESCO Finland
Orbita CT
20.2
8.5
12
6
H50.39
ICD-10 Finland
Intermittent heterotropia
90.6
8.4
9
*
CEE00
NOMESCO Finland
Posterior fixation suture of extraocular muscle
+∞
8.3
8
*
H25.8
ICD-10 Finland
Other senile cataract
1.8
8.3
125
721
A02BC05
ATC
esomeprazole; systemic
1.4
8.3
509
4038
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.3
963
8513
N06AX11
ATC
mirtazapine; oral
1.4
8.2
438
3388
N02AX02
ATC
tramadol; systemic, rectal
1.4
8.1
533
4278
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
8.0
126
736
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
6.6
7.9
19
29
S01EE01
ATC
latanoprost; ophthalmic
2.1
7.9
75
371
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
7.8
305
2221
WX725
NOMESCO Finland
Noninvasive ventilation
2.0
7.8
80
407
Z01.2
ICD-10 Finland
Dental examination
1.4
7.7
612
5052
R1250, ,
SPAT
2.5
7.7
48
198
L17
ICPC
Foot/toe symptom/complaint
1.4
7.7
399
3065
N03AX16
ATC
[U] pregabalin
1.5
7.7
281
2020
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.7
77
388
E0000UV, ,
ATC
1.4
7.7
537
4344
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.5
462
3652
N28
ICPC
Limited function/disability (N)
3.3
7.5
27
82
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
3.7
7.5
23
63
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.4
355
2685
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
7.3
97
539
N05CF01
ATC
zopiclone; oral
1.4
7.3
382
2936
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
7.3
7
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
3.6
7.2
23
65
XKD00
NOMESCO Finland
Uroflowmetry
1.6
7.2
162
1046
A02BC02
ATC
pantoprazole; systemic
1.4
7.1
874
7688
S06.0
ICD-10 Finland
Concussion
1.6
7.1
150
952
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.1
279
2033
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.9
1186
11022
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.8
171
1132
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.8
635
5347
N03AX09
ATC
lamotrigine; oral
2.0
6.7
66
331
SPAT1360
SPAT
Extensive global examination
1.9
6.7
82
444
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
3.7
6.6
20
54
A04
ICPC
Weakness/tiredness general
1.5
6.6
207
1438
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
8.7
6.6
13
15
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.5
308
2318
CD2S4
NOMESCO Finland
Photography of eye
6.9
6.5
15
22
R06.0
ICD-10 Finland
Dyspnoea
1.4
6.4
341
2618
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
6.4
86
479
F80.1
ICD-10 Finland
Expressive language disorder
4.0
6.4
18
46
XCW11
NOMESCO Finland
Assessment of strabismus
70.2
6.4
7
*
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
70.2
6.4
7
*
P85
ICPC
Mental retardation
14.4
6.4
10
7
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.4
183
1248
R01AD09
ATC
mometasone; nasal
1.3
6.4
581
4857
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
6.4
580
4849
H26.02
ICD-10 Finland
Presenil cataract
2.5
6.3
37
149
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.5
6.3
21
61
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
18.1
6.3
9
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.3
319
2432
CED00
NOMESCO Finland
Plication of extraocular muscle
+∞
6.3
6
*
3781X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALIUS]
+∞
6.3
6
*
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
6.3
6
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
26.8
6.2
8
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.5
6.2
36
144
R51.80
ICD-10 Finland
Headache
1.5
6.2
205
1440
S18
ICPC
Laceration/cut
1.3
6.2
595
5006
EB1VA, ,
NOMESCO Finland
1.5
6.2
224
1603
114
Kela drug reimbursment
Glaucoma
1.8
6.1
95
554
SPAT1229
SPAT
Assessment of need for aid
1.8
6.1
83
465
H40.0
ICD-10 Finland
Glaucoma suspect
1.8
6.1
92
532
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.0
6.1
25
83
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
2.8
6.1
29
105
H02.3
ICD-10 Finland
Blepharochalasis
1.9
6.1
79
437
Z31.5
ICD-10 Finland
Genetic counselling
1.9
6.0
72
387

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
72
10.49
64.17
1.2
1.1
3.50
1.68
nmol/l
0.36
17
13
130
358
3.90
41.55
3.6
2.0
6.36
19.00
iu/l
0.40
73
155
720
5486
1.65
18.23
7.0
6.6
1.21
1.21
mmol/l
0.04
669
5104
782
6141
1.62
17.07
7.7
7.2
1.21
1.21
mmol/l
0.06
681
5352
519
3709
1.64
16.48
2.3
2.2
271.80
211.86
u/l
0.50
494
3517
156
796
2.08
15.00
4.9
3.4
4.47
4.57
pmol/l
0.58
144
702
855
7138
1.51
12.21
5.6
5.1
6.46
6.64
mmol/l
2.09
817
6746
1081
9554
1.59
11.40
6.2
4.4
14.83
14.72
pmol/l
0.74
1013
8854
672
5423
1.46
10.81
4.7
5.1
36.27
35.83
g/l
1.29
635
5101
670
5467
1.43
9.81
13.6
14.3
1.23
1.24
inr
0.09
552
4542
1042
9240
1.51
9.78
8.4
8.2
80.32
79.53
u/l
0.14
996
8803
64
270
2.44
9.74
2.1
1.7
—
—
—
0
0
1216
11179
1.69
9.66
7.3
5.4
1.82
1.89
mu/l
1.39
1144
10431
923
8013
1.45
9.47
5.7
4.6
3292.14
2312.87
e6/l
0.16
14
109
280
1941
1.55
9.23
1.7
1.7
1032.02
1178.76
nmol/l
2.09
205
1476
196
1252
1.66
9.07
2.2
2.1
354.59
384.37
nmol/l
1.40
176
1171
471
3675
1.43
8.49
4.4
4.1
7.40
7.40
ph
0.70
354
2645
724
6093
1.39
8.36
6.8
6.5
28.30
28.09
%
0.22
694
5811
708
5946
1.39
8.22
6.9
6.6
8.84
8.76
%
0.32
675
5605
712
5991
1.39
8.15
6.6
6.4
57.22
57.02
%
0.18
687
5748
705
5934
1.38
7.99
6.8
6.5
2.81
2.83
%
0.10
670
5591
1276
12014
1.75
7.64
21.5
18.2
3.96
3.96
mmol/l
0.11
1260
11767
1274
11998
1.73
7.52
21.4
18.0
139.73
139.64
mmol/l
0.66
1257
11771
701
5935
1.36
7.46
7.0
6.6
0.71
0.68
%
0.83
667
5577
1263
11890
1.67
7.16
18.0
15.6
22.73
23.73
mg/l
0.47
1061
9772
407
3172
1.40
7.15
4.2
4.2
87.96
90.31
%
1.18
399
3108
38
146
2.65
7.08
2.5
1.8
—
—
—
0
0
237
1675
1.50
7.01
5.2
5.8
1.05
1.05
mmol/l
0.09
220
1563
524
4274
1.36
6.92
6.7
6.3
—
—
—
0
0
758
6545
1.35
6.86
6.7
6.4
1.91
1.93
e9/l
0.18
664
5776
679
5773
1.34
6.78
2.8
2.8
—
—
estimate
—
0
0
227
1605
1.50
6.68
3.2
3.3
4.50
4.99
e9/l
0.37
186
1415
639
5405
1.34
6.52
2.3
2.1
96.85
95.46
pmol/l
0.33
337
2860
524
4308
1.35
6.46
3.3
3.5
2.35
2.36
mmol/l
0.40
465
3932
37
148
2.54
6.39
2.6
2.1
—
—
—
0
0
147
953
1.61
6.38
4.2
3.8
76.16
84.81
ng/l
0.74
126
843
739
6410
1.33
6.22
5.8
6.7
11.54
11.64
umol/l
0.09
704
6131
760
6623
1.32
6.17
6.9
6.6
0.19
0.19
e9/l
0.15
667
5799
1289
12271
1.68
6.07
16.2
13.7
—
—
—
0
0
256
1886
1.44
6.07
2.0
2.2
29.72
29.47
s
0.21
247
1834
738
6414
1.32
6.06
6.8
6.3
0.57
0.58
e9/l
0.15
639
5516
739
6424
1.32
6.06
6.8
6.4
0.04
0.04
e9/l
0.19
638
5525
59
296
2.04
6.02
2.2
1.7
19.23
33.96
e6/l
0.33
43
219
667
5722
1.32
5.98
2.8
2.5
77.47
76.53
nmol/l
0.38
606
5218
556
4650
1.33
5.97
4.2
3.9
90.55
87.82
e6/l
0.03
389
3234
27
95
2.88
5.96
1.1
1.2
48.06
41.28
mg/l
0.26
21
77
581
4894
1.32
5.92
2.2
2.2
—
—
—
0
0
924
8311
1.33
5.85
3.5
3.3
44.97
45.90
u/l
0.13
882
7880
1184
11087
1.45
5.77
6.7
6.2
38.59
38.95
mmol/mol
0.83
1114
10478
59
301
2.00
5.76
2.2
1.7
1000.42
791.85
e6/l
0.11
45
233
275
2075
1.41
5.68
2.6
3.4
0.82
0.82
mmol/l
0.03
263
1972
151
1013
1.55
5.67
2.7
2.9
10.74
10.80
g/l
0.06
138
943
808
7152
1.31
5.62
9.9
9.5
4.04
4.09
e9/l
0.27
708
6236
58
297
1.99
5.61
1.3
1.5
3.72
3.72
mmol/l
0.01
53
283
488
4044
1.32
5.48
2.5
2.4
—
—
—
0
0
1309
12556
1.71
5.41
23.2
19.8
75.80
75.61
umol/l
0.07
1299
12422
122
790
1.60
5.34
1.4
1.3
43.53
45.82
au/ml
—
6
53
388
3128
1.33
5.24
1.4
1.3
0.88
1.85
u/ml
2.68
108
854
483
4018
1.31
5.22
3.5
3.3
45.75
75.77
e6/l
0.71
370
3065
48
238
2.05
5.09
3.3
2.1
—
—
—
0
0
430
3541
1.31
4.95
1.8
1.7
20.10
20.48
nmol/l
0.21
357
3020
1200
11335
1.43
4.91
5.5
5.0
5.87
5.90
mmol/l
0.38
1115
10490
1231
11692
1.46
4.79
5.1
5.0
4.55
4.64
mmol/l
2.56
1150
11008
128
863
1.53
4.72
2.6
2.5
18.79
20.68
au/ml
0.15
11
88
376
3066
1.31
4.60
2.4
2.4
—
—
—
0
0
1242
11835
1.46
4.56
5.9
5.6
2.65
2.72
mmol/l
2.01
1159
11102
225
1710
1.38
4.40
2.2
2.6
195.41
118.51
ug/g
0.95
171
1369
452
3795
1.28
4.40
6.5
6.3
—
—
—
0
0
1298
12494
1.58
4.40
13.5
11.9
26.14
25.96
u/l
0.13
1265
12192
223
1695
1.38
4.36
1.2
1.2
—
—
—
0
0
524
4492
1.27
4.28
4.1
3.7
27.99
75.23
ng/l
1.40
370
3065
495
4215
1.27
4.27
3.6
3.5
7.37
7.59
mmol/l
0.57
428
3605
742
6626
1.26
4.26
4.4
3.9
0.01
0.24
estimate
0.49
144
1311
43
220
1.98
4.24
1.3
1.6
0.96
0.89
g/l
0.10
35
179
734
6573
1.25
4.01
4.3
3.8
0.00
4.59
estimate
1.33
152
1400
1220
11639
1.39
3.96
5.1
4.9
1.44
1.47
mmol/l
1.78
1133
10888
274
2180
1.32
3.95
2.9
3.0
0.75
1.04
e6/l
1.48
140
1148
371
3077
1.28
3.91
2.8
2.8
341.06
338.45
umol/l
0.19
330
2742
182
1365
1.38
3.86
8.6
8.3
7.41
7.41
ph
0.45
98
752
294
2370
1.30
3.85
3.0
2.9
540.39
526.59
mosm/kgh2o
0.46
251
2082
59
346
1.74
3.84
1.8
2.4
11.81
11.92
mg/l
0.04
52
320
441
3745
1.26
3.81
3.7
3.0
—
—
—
0
0
182
1370
1.38
3.78
8.7
8.2
5.17
5.13
kpa
0.21
174
1323
182
1371
1.38
3.76
8.7
8.2
13.24
12.25
kpa
1.55
175
1326
600
5281
1.24
3.75
3.8
3.4
6.29
6.22
ph
0.85
310
3005
333
2745
1.28
3.66
1.6
1.5
2.18
2.36
g/l
1.42
215
1700
149
1091
1.41
3.64
4.0
4.1
7.41
7.36
ph
4.16
106
803
70
437
1.63
3.63
1.4
1.2
—
—
—
0
0
410
3472
1.26
3.59
2.9
3.1
1688.68
1203.85
ng/l
0.59
337
2950
229
1800
1.33
3.58
1.3
1.3
497.14
487.69
titre
0.02
42
385
254
2028
1.31
3.56
3.0
3.1
2.76
2.63
e6/l
0.06
120
991
178
1353
1.36
3.48
8.7
8.2
0.74
0.93
mmol/l
0.28
148
1128
163
1223
1.38
3.46
8.7
8.5
96.51
95.59
%
1.99
158
1187
468
4037
1.24
3.46
3.8
3.5
—
0.71
—
0
14
721
6508
1.22
3.44
4.4
3.8
0.00
0.00
estimate
0.50
147
1374
7
10
7.03
3.36
2.7
2.2
—
—
—
0
0
451
3891
1.24
3.30
2.7
2.6
56.22
81.53
u/l
0.66
420
3620
304
2511
1.27
3.26
1.8
1.7
459.84
23507718.95
pmol/l
1.97
259
2127
407
3479
1.24
3.23
3.6
3.3
0.33
0.42
e6/l
0.35
296
2543
19
78
2.46
3.22
1.3
1.2
0.51
0.54
ratio
—
10
48
1163
11092
1.29
3.18
4.3
4.2
1.27
1.28
mmol/l
0.18
1070
10285
574
5095
1.22
3.15
1.9
1.9
1.33
1.36
mmol/l
0.55
499
4347
387
3304
1.24
3.09
2.6
2.3
2.65
2.81
mg/l
0.83
327
2848
6
8
7.53
3.05
1.3
1.5
—
—
—
0
0
391
3348
1.23
3.03
4.6
4.2
—
—
—
0
0
333
2803
1.25
3.02
1.8
1.8
1.29
1.29
mg/l
0.00
258
2167
126
928
1.39
3.01
1.3
1.2
156.93
143.35
u/ml
0.16
57
372
283
2348
1.26
2.90
3.9
3.9
174.46
376.49
ng/l
1.87
214
1780
67
440
1.55
2.87
3.2
1.8
—
—
—
0
0
72
482
1.52
2.83
1.9
2.4
20.20
20.79
s
0.70
59
440
131
984
1.37
2.79
2.4
3.0
66.73
66.78
g/l
0.02
122
919
11
34
3.25
2.73
1.0
1.7
—
—
—
0
0
1328
12976
1.51
2.68
28.4
23.6
251.88
252.73
e9/l
0.18
1313
12737
117
871
1.37
2.64
3.5
3.8
5.24
5.14
kpa
0.53
111
848
173
1369
1.30
2.60
2.5
2.8
1.75
1.80
%
0.26
154
1235
1328
12983
1.50
2.59
28.3
23.5
90.92
90.86
fl
0.17
1320
12860
1328
12984
1.50
2.58
29.0
24.0
40.49
40.65
%
0.17
1320
12851
1328
12984
1.50
2.58
28.4
23.6
4.50
4.49
e12/l
0.17
1310
12711
1328
12984
1.50
2.58
28.3
23.5
30.29
30.27
pg
0.15
1320
12859
114
850
1.37
2.56
3.5
3.8
7.41
7.42
ph
0.19
96
714
1328
12987
1.49
2.54
28.4
23.6
6.75
6.72
e9/l
0.18
1310
12709
97
706
1.40
2.52
1.1
1.1
—
0.96
—
0
8
1328
12989
1.49
2.51
28.6
23.7
135.36
135.05
g/l
0.37
1319
12864
25
129
1.96
2.51
1.3
1.3
—
—
—
0
0
25
129
1.96
2.51
1.3
1.3
0.49
0.40
g/l
0.47
19
100
25
129
1.96
2.51
1.3
1.3
3.45
2.86
g/l
0.50
19
100
25
129
1.96
2.51
1.3
1.3
6.99
7.13
g/l
0.06
19
101
479
4250
1.19
2.51
3.3
3.3
29.52
32.65
u/l
1.76
456
4026
322
2753
1.22
2.49
3.1
2.6
5.12
6.36
e6/l
0.89
294
2514
141
1094
1.32
2.45
1.2
1.2
—
—
—
0
0
344
2966
1.21
2.44
4.2
3.7
—
0.17
—
0
29
11
38
2.91
2.41
1.1
1.5
62.18
80.13
nmol/24h
0.61
11
38
435
3840
1.19
2.39
3.5
3.5
39.63
48.47
mg/l
0.40
270
2479
13
52
2.51
2.36
3.8
1.5
—
—
—
0
0
135
1047
1.32
2.36
1.5
1.5
—
—
—
0
0
82
589
1.42
2.31
2.5
2.3
—
—
—
0
0
12
48
2.51
2.19
6.5
3.0
—
—
—
0
0
58
395
1.49
2.17
4.7
2.2
—
—
—
0
0
664
6111
1.17
2.15
3.5
3.1
98.24
113.47
ug/l
2.00
624
5745
70
496
1.43
2.14
2.0
1.6
372.53
295.51
mu/l
0.83
64
447
140
1107
1.29
2.14
9.6
9.1
—
—
—
0
0
19
356
0.53
2.10
7.9
10.5
—
—
—
0
0
51
342
1.51
2.06
3.0
3.3
1.49
2.06
index
0.39
31
176
152
1222
1.27
2.05
2.4
2.4
28.47
41.74
u/l
2.39
124
1025
11
44
2.51
2.01
1.7
1.5
42.04
40.53
g/l
0.62
11
44
80
1071
0.73
2.00
1.5
1.7
3.23
3.48
mmol/l
1.00
51
745
82
606
1.38
2.00
3.8
4.1
—
—
—
0
0
144
1155
1.28
1.98
2.0
2.1
0.00
0.02
estimate
0.78
30
245
242
2057
1.21
1.98
2.6
2.5
13.08
13.09
umol/l
0.01
230
1929
103
790
1.33
1.98
10.7
10.2
1.35
1.31
%
0.10
103
784
13
57
2.29
1.98
2.5
3.5
754.31
732.28
u/ml
0.03
13
57
8
27
2.97
1.93
1.0
1.0
6.36
7.04
mg/g
—
8
27
58
408
1.44
1.88
1.7
1.4
10.67
9.55
u/l
0.19
48
320
12
52
2.32
1.88
6.5
2.8
—
—
—
0
0
104
806
1.31
1.87
2.3
2.6
—
—
—
0
0
99
762
1.32
1.87
11.1
10.5
0.72
0.64
%
0.40
99
757
8
28
2.87
1.86
1.0
1.0
—
—
—
0
0
436
3922
1.16
1.84
4.3
4.2
7.86
8.21
mg/mmol
0.04
265
2458
399
3569
1.17
1.81
4.6
3.9
0.00
0.01
estimate
1.54
145
1283
93
713
1.33
1.81
1.4
1.4
24.63
25.61
iu/l
0.11
78
599
8
29
2.77
1.79
1.0
1.0
15.96
17.34
umol/l
—
8
24
27
161
1.69
1.79
2.9
2.7
—
—
—
0
0
70
516
1.38
1.76
1.8
1.8
4.98
7.37
iu/ml
0.64
16
115
330
2917
1.17
1.74
4.7
3.9
1.02
1.54
kg/l
0.50
220
1934
29
178
1.64
1.73
1.1
1.2
—
—
—
0
0
22
126
1.76
1.68
1.1
1.1
—
—
—
0
0
131
1063
1.26
1.67
2.7
2.8
68.60
70.62
e9/l
0.26
97
775
223
1917
1.19
1.63
2.6
2.5
2.39
2.32
g/l
0.96
210
1789
190
1610
1.21
1.62
1.4
1.3
—
—
—
0
0
7
26
2.70
1.58
1.1
1.0
—
—
—
0
0
29
183
1.60
1.58
1.1
1.1
1.00
2.06
eliau/ml
1.62
11
79
211
1816
1.19
1.53
2.1
2.0
—
—
—
0
0
226
1957
1.18
1.53
3.1
3.2
0.74
0.75
ug/l
0.05
154
1241
118
958
1.25
1.52
3.4
3.7
1.23
1.23
mmol/l
0.03
104
828
35
234
1.51
1.50
1.4
1.4
89.32
60.55
mmol/l
1.93
25
195
69
523
1.34
1.49
3.1
1.9
—
—
—
0
0
275
2426
1.17
1.49
3.0
2.9
2.43
2.45
mmol/l
1.50
246
2179
175
1485
1.20
1.48
2.1
1.7
—
—
—
0
0
53
386
1.39
1.47
3.1
3.9
26.61
44.03
mg/l
1.53
46
330
53
387
1.38
1.45
3.1
3.9
43.72
62.36
mg/l
0.57
46
330
24
148
1.63
1.44
1.3
1.1
—
—
—
0
0
132
1093
1.23
1.43
4.9
7.3
8.47
9.17
mmol/l
0.68
124
1053
364
3288
1.14
1.42
5.5
5.5
4.61
2.65
ug/l
0.33
334
2969
180
1538
1.20
1.42
1.5
1.4
—
—
—
0
0
118
968
1.24
1.40
2.8
2.4
13.11
12.77
nmol/l
0.17
106
878
597
5570
1.13
1.40
12.9
11.2
0.00
0.00
e9/l
0.24
489
4535
73
564
1.31
1.40
3.1
1.8
—
—
—
0
0
168
1429
1.20
1.40
1.2
1.3
—
—
—
0
0
73
565
1.31
1.38
2.7
1.8
—
—
—
0
0
73
565
1.31
1.38
2.7
1.8
—
—
—
0
0
73
568
1.30
1.34
3.2
1.8
—
—
—
0
0
75
587
1.29
1.32
2.1
2.1
0.00
0.02
estimate
0.68
17
189
6
24
2.51
1.30
1.8
1.2
21.48
0.10
u/ml
—
6
24
18
106
1.71
1.29
1.1
1.3
—
—
—
0
0
171
1469
1.19
1.29
2.5
3.0
7.19
7.90
umol/l
0.22
152
1301
46
336
1.38
1.28
1.2
1.1
0.58
5.41
eliau/ml
—
6
44
23
146
1.59
1.26
1.4
1.6
30.21
23.91
ng/l
0.38
23
146
285
2554
1.15
1.25
2.0
2.0
—
—
—
0
0
44
321
1.38
1.24
1.1
1.1
—
—
—
0
0
51
382
1.35
1.23
1.6
1.4
260.67
285.15
ug/g
0.34
29
222
5
19
2.64
1.21
1.4
1.1
—
—
—
0
0
41
297
1.39
1.21
1.3
1.2
31.86
50.40
u/ml
—
7
30
119
1413
0.83
1.19
1.8
1.9
3.52
3.45
ratio
0.18
91
1084
13
71
1.84
1.19
1.5
1.4
26.17
25.69
umol/l
0.02
13
62
15
86
1.75
1.19
1.2
1.5
11.27
11.76
umol/l
0.13
15
80
8
38
2.11
1.18
1.0
1.1
—
—
—
0
0
8
38
2.11
1.18
1.0
1.1
—
—
—
0
0
8
38
2.11
1.18
1.0
1.1
—
—
—
0
0
107
889
1.22
1.16
2.5
3.0
145.80
183.54
ng/l
0.61
99
819
29
201
1.45
1.10
1.8
1.8
—
—
—
0
0
7
136
0.51
1.10
1.1
1.2
—
—
—
0
0
179
1567
1.16
1.10
1.7
1.6
—
—
—
0
0
240
2148
1.14
1.08
1.7
1.7
—
—
—
0
0
267
2407
1.14
1.08
1.4
1.3
27.78
31.55
iu/ml
0.20
72
719
26
177
1.48
1.08
4.8
3.6
0.98
1.32
%
0.39
21
166
1042
10116
1.12
1.06
23.2
19.1
13.56
13.56
%
0.03
1030
9992
198
1755
1.15
1.03
2.7
2.5
21.80
22.77
%
0.53
183
1653
11
60
1.84
1.03
1.9
3.7
121.33
111.89
umol/l
—
6
35
27
188
1.44
1.02
3.9
5.9
406.41
356.12
umol/l
0.94
22
171
20
131
1.53
1.00
1.9
1.6
56.43
57.23
%
0.03
14
87
19
123
1.55
1.00
4.8
2.6
—
—
—
0
0
18
115
1.57
0.99
2.2
2.3
44.72
40.23
%
0.76
18
115
41
310
1.33
0.97
1.1
1.1
1.03
3.50
u/ml
1.54
22
175
17
108
1.58
0.96
1.4
1.1
—
—
—
0
0
45
347
1.31
0.94
2.2
3.8
4.14
3.34
ratio
0.10
28
193
56
446
1.27
0.92
1.3
1.3
130.89
228.45
miu/ml
1.41
19
213
10
55
1.82
0.92
1.7
2.1
1.84
1.89
umol/l
—
10
49
31
227
1.37
0.91
3.5
3.2
3.47
4.23
e9/l
1.85
31
227
6
30
2.00
0.87
2.2
1.1
168.61
0.93
u/ml
—
6
19
8
44
1.82
0.86
30.9
35.8
95.63
129.67
ug/l
—
8
36
24
170
1.42
0.85
2.0
1.8
—
2146.67
—
0
6
38
291
1.31
0.85
3.1
3.1
57.66
58.07
%
0.08
38
291
13
203
0.64
0.84
1.2
1.3
—
—
—
0
0
10
57
1.76
0.83
1.5
1.7
—
72.26
—
0
9
244
2226
1.12
0.83
1.3
1.3
8.36
12.36
u/ml
0.50
100
846
21
146
1.45
0.82
1.2
1.2
—
—
—
0
0
46
364
1.27
0.82
1.1
1.2
—
—
—
0
0
63
518
1.23
0.81
2.0
2.0
1.27
1.47
g/l
1.22
54
465
6
33
1.82
0.79
1.7
1.4
53.95
52.16
mu/l
—
6
28
8
48
1.67
0.78
1.0
1.0
—
—
—
0
0
12
74
1.63
0.78
1.3
2.9
16.32
16.68
%
0.17
12
74
108
938
1.16
0.78
2.1
2.4
10.51
7.29
ug/l
0.44
86
839
106
920
1.16
0.77
1.5
1.3
266.97
213.07
u/ml
0.19
98
853
17
115
1.48
0.77
1.1
1.2
—
—
—
0
0
102
1171
0.86
0.75
1.3
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
2.1
—
—
—
0
0
63
524
1.21
0.74
2.3
2.2
3472.00
6696.90
u/l
0.88
25
211
66
552
1.21
0.74
1.2
1.2
—
—
—
0
0
147
1315
1.13
0.71
4.2
4.0
7.38
7.38
ph
0.55
94
751
9
58
1.56
0.70
1.2
1.4
33.22
31.73
nmol/l
—
9
48
23
169
1.37
0.69
2.0
2.6
5.95
9.00
umol/l
0.50
13
126
12
77
1.56
0.68
1.8
2.7
7.51
8.47
mmol/l
0.69
12
77
10
61
1.64
0.68
1.0
2.0
24.47
29.91
umol/l
—
10
55
16
110
1.46
0.68
1.1
1.1
—
178.00
—
0
15
25
187
1.34
0.68
2.1
1.7
—
—
—
0
0
30
231
1.31
0.68
1.0
1.1
1.56
3.84
u/ml
0.95
17
114
39
484
0.80
0.67
1.1
1.1
1.56
1.55
g/l
0.09
39
484
34
267
1.28
0.67
1.1
1.1
3.99
1.77
u/ml
0.49
15
141
27
206
1.32
0.65
1.2
1.2
4.22
5.49
u/ml
—
9
89
19
137
1.39
0.64
1.4
2.6
0.13
1.22
g/24h
—
7
83
17
120
1.42
0.64
6.8
4.1
—
—
—
0
0
52
432
1.21
0.64
2.4
2.7
—
—
—
0
0
41
502
0.81
0.63
1.1
1.2
0.81
0.91
g/l
2.56
41
502
49
407
1.21
0.61
1.4
1.6
1.19
1.20
g/l
0.09
49
385
5
30
1.67
0.61
1.8
1.4
—
—
—
0
0
31
244
1.28
0.61
2.2
2.9
7.26
7.98
pmol/l
0.23
31
244
21
156
1.35
0.61
2.0
1.5
290.56
279.61
mosm/kgh2o
1.76
16
116
19
255
0.74
0.60
1.1
1.1
10.40
18.07
au/ml
—
5
65
38
308
1.24
0.60
1.3
1.2
—
—
—
0
0
11
72
1.53
0.59
1.3
1.2
—
—
—
0
0
34
273
1.25
0.58
1.1
1.1
3.38
4.78
u/ml
0.37
20
155
37
451
0.82
0.57
1.1
1.1
0.52
0.67
ratio
—
8
56
381
3620
1.07
0.55
1.5
1.5
—
—
—
0
0
16
116
1.38
0.54
3.6
3.6
16.40
12.01
index
—
10
75
16
116
1.38
0.54
2.0
1.3
42202.33
196928.42
e6/l
—
9
78
120
1083
1.12
0.54
6.1
4.9
2.32
0.13
%
0.49
31
260
78
685
1.15
0.53
1.7
1.7
—
—
—
0
0
95
847
1.13
0.52
1.2
1.2
—
—
—
0
0
31
251
1.24
0.51
1.5
1.7
—
—
—
0
0
458
4772
0.94
0.50
2.9
3.0
—
—
—
0
0
49
573
0.85
0.50
1.6
1.7
0.26
0.33
mg/l
0.75
25
273
49
418
1.18
0.49
1.8
2.6
9.58
10.65
g/l
0.84
42
381
19
145
1.31
0.49
1.1
1.3
0.15
0.18
nmol/l
0.91
13
113
138
1264
1.10
0.48
4.1
4.1
1.13
1.78
mmol/l
1.16
126
1075
43
363
1.19
0.48
1.2
1.2
—
—
—
0
0
140
1521
0.91
0.47
1.5
1.5
—
—
—
0
0
7
48
1.46
0.47
1.0
1.0
—
—
—
0
0
7
48
1.46
0.47
2.0
1.8
28.57
29.69
%
—
7
48
22
173
1.28
0.46
1.5
3.0
—
—
—
0
0
13
94
1.39
0.46
1.1
1.0
—
—
—
0
0
26
210
1.24
0.45
1.0
1.1
2.61
6.61
u/ml
0.81
14
90
7
50
1.40
0.45
1.4
1.3
—
—
—
0
0
22
175
1.26
0.43
2.1
1.8
1.51
1.69
mmol/l
0.59
22
169
15
196
0.76
0.43
1.2
1.2
—
—
—
0
0
22
273
0.80
0.42
3.2
4.7
—
—
—
0
0
5
32
1.56
0.42
1.2
1.2
—
—
—
0
0
24
194
1.24
0.42
1.0
1.1
0.11
0.36
u/ml
0.85
11
65
122
1122
1.10
0.41
5.6
4.6
0.65
0.98
%
0.90
36
336
8
58
1.38
0.41
1.1
1.1
237.25
168.93
iu/ml
—
8
58
117
1074
1.10
0.41
5.8
4.4
0.94
0.62
%
0.59
36
317
14
105
1.34
0.41
1.2
1.1
99.64
110.33
pmol/l
0.54
14
105
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
18
141
1.28
0.40
1.3
1.4
—
—
—
0
0
24
292
0.82
0.39
1.6
1.5
—
—
—
0
0
74
665
1.12
0.39
1.3
1.3
—
—
—
0
0
5
36
1.39
0.38
1.0
1.3
28.00
28.11
s
—
5
36
9
68
1.33
0.37
1.0
1.4
111.11
145.85
nmol/l
—
9
68
5
37
1.35
0.37
5.4
2.7
2.72
3.29
mmol/l
—
5
31
150
1401
1.08
0.37
1.7
1.8
—
—
—
0
0
10
72
1.39
0.37
1.1
1.9
59.00
105.44
ng/l
—
10
72
25
299
0.83
0.36
1.6
1.6
—
—
—
0
0
6
44
1.37
0.34
1.0
1.5
—
—
—
0
0
31
265
1.17
0.33
1.1
1.1
0.44
0.76
u/ml
0.70
16
126
31
266
1.17
0.32
1.2
1.4
—
—
—
0
0
10
75
1.34
0.30
2.8
3.9
1.80
0.89
index
—
10
75
24
203
1.19
0.30
1.5
1.4
—
9.50
—
0
6
72
659
1.10
0.30
2.5
3.4
67.36
77.38
u/ml
0.10
72
638
13
163
0.80
0.29
1.0
1.2
—
—
—
0
0
38
335
1.14
0.29
1.2
1.3
—
—
—
0
0
375
3632
1.04
0.29
3.7
3.2
0.08
0.04
estimate
0.21
130
1110
18
148
1.22
0.29
2.3
2.3
—
—
—
0
0
7
57
1.23
0.29
1.1
1.4
140.00
168.94
mmol/24h
—
7
57
9
117
0.77
0.27
1.6
1.5
—
—
—
0
0
9
117
0.77
0.27
1.8
1.7
—
—
—
0
0
12
150
0.80
0.27
1.2
1.3
—
—
nmol/l
—
0
0
13
104
1.25
0.26
1.0
1.2
—
—
—
0
0
69
637
1.09
0.25
1.1
1.1
—
—
—
0
0
34
302
1.13
0.24
2.4
2.1
131.54
131.30
g/l
0.02
24
244
295
2855
1.04
0.24
5.2
4.6
—
—
—
0
0
127
1203
1.06
0.24
2.0
2.4
0.22
0.21
g/l
0.12
117
1120
22
253
0.87
0.22
1.1
1.1
—
—
—
0
0
48
439
1.10
0.22
4.3
3.9
252.50
434.31
mg/l
0.71
28
201
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.3
—
97.09
—
0
11
8
101
0.79
0.21
1.3
1.3
—
—
—
0
0
8
103
0.78
0.21
1.0
1.5
—
—
—
0
0
5
43
1.16
0.21
1.2
1.5
—
—
—
0
0
22
251
0.87
0.21
1.1
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
267.15
—
0
8
6
49
1.23
0.20
2.2
2.3
—
—
—
0
0
113
1075
1.06
0.20
6.0
4.6
0.00
0.12
%
6.17
27
286
58
539
1.08
0.19
2.9
3.2
25.63
25.39
mmol/l
0.21
58
513
6
51
1.18
0.19
32.0
29.9
4.77
7.07
ug/l
—
6
46
103
979
1.06
0.19
3.6
2.6
6.07
6.10
ph
0.14
68
663
29
261
1.11
0.18
4.2
3.5
—
—
—
0
0
30
272
1.11
0.17
1.6
3.3
28.00
34.23
umol/l
1.51
24
245
5
69
0.72
0.17
1.0
1.3
142.86
161.67
pmol/l
—
5
69
24
215
1.12
0.16
1.0
1.1
—
—
—
0
0
24
215
1.12
0.16
1.0
1.1
—
—
—
0
0
32
292
1.10
0.16
1.4
1.5
61.00
217.49
pmol/l
2.05
32
287
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
30
275
1.09
0.14
1.8
1.2
—
—
—
0
0
51
479
1.07
0.14
3.9
3.5
2303.15
3036.01
u/ml
0.10
46
419
12
139
0.86
0.14
1.2
1.2
—
—
—
0
0
45
480
0.94
0.14
1.7
1.6
9.65
12.04
u/ml
0.22
13
117
17
151
1.13
0.13
2.8
2.3
31.06
32.62
pg
0.54
17
151
23
209
1.10
0.13
1.2
1.1
42.07
92.09
iu/ml
—
6
47
503
4965
1.02
0.12
4.5
3.7
0.00
0.06
estimate
2.00
125
1151
42
394
1.07
0.12
3.4
3.9
1.39
1.35
mmol/l
0.09
42
387
17
189
0.90
0.12
1.3
1.7
—
—
—
0
0
13
115
1.13
0.10
1.0
1.1
—
—
—
0
0
19
173
1.10
0.10
1.2
1.3
—
0.52
nmol/l
—
0
12
101
1040
0.97
0.09
1.4
1.4
—
—
—
0
0
127
1239
1.03
0.09
3.4
4.3
135.72
24.16
ug/l
0.40
102
1013
5
61
0.82
0.08
1.0
1.2
90.80
452.64
u/l
—
5
55
7
66
1.06
0.08
1.0
1.7
—
—
—
0
0
23
246
0.93
0.08
3.7
3.3
6.91
7.45
mmol/l
0.52
23
240
50
480
1.04
0.08
2.0
1.8
2.40
1.96
ug/l
0.10
37
429
6
70
0.86
0.07
1.2
1.2
14.50
9.07
mm/h
—
6
70
56
580
0.96
0.07
1.9
1.9
—
—
—
0
0
39
373
1.05
0.07
2.3
1.9
—
—
—
0
0
8
91
0.88
0.06
1.0
1.0
—
—
—
0
0
12
132
0.91
0.06
2.1
2.2
—
—
—
0
0
144
1415
1.02
0.06
1.8
1.7
—
—
—
0
0
22
207
1.06
0.06
1.4
1.2
—
—
—
0
0
13
120
1.08
0.05
1.7
2.2
—
—
—
0
0
29
278
1.04
0.04
1.3
1.2
243.71
264.42
u/ml
0.14
14
161
10
91
1.10
0.04
1.1
1.1
—
75.89
—
0
7
45
463
0.97
0.04
1.2
1.3
—
—
—
0
0
26
269
0.97
0.02
1.5
2.0
0.88
0.86
nmol/l
0.04
21
232
101
998
1.01
0.02
4.5
3.8
—
—
—
0
0
11
104
1.06
0.01
1.2
1.1
—
—
—
0
0
48
486
0.99
0.00
1.0
1.1
—
—
—
0
0
10
96
1.04
0.00
1.2
1.1
—
—
—
0
0
12
116
1.03
0.00
1.7
1.4
111078.71
60993.86
e6/l
—
7
59
25
246
1.02
0.00
1.2
1.5
167.00
148.65
au/ml
0.37
12
73
31
314
0.99
0.00
1.9
1.6
20825.54
12255.24
e6/l
0.35
24
224
12
119
1.01
0.00
1.3
1.3
2.47
3.72
u/ml
—
6
62
23
231
1.00
0.00
5.0
3.9
2.41
2.46
mmol/l
0.04
17
157
27
269
1.00
0.00
2.5
2.5
9.70
113.81
ug/min
4.38
13
163
12
117
1.03
0.00
1.5
1.4
—
—
—
0
0
13
127
1.02
0.00
2.6
2.6
106.62
105.64
mmol/l
0.43
13
127
13
127
1.02
0.00
2.6
2.6
3.99
4.01
mmol/l
0.05
13
127
32
317
1.01
0.00
3.8
4.1
3.78
3.87
mmol/l
0.88
32
312
17
175
0.97
0.00
1.2
1.6
—
—
—
0
0
17
175
0.97
0.00
1.2
1.6
—
—
—
0
0
17
175
0.97
0.00
1.2
1.6
—
—
—
0
0
17
175
0.97
0.00
1.2
1.6
—
—
—
0
0
25
255
0.98
0.00
2.8
3.5
22.09
25.48
mg/l
0.25
17
174
12
125
0.96
0.00
2.7
2.7
1.19
1.19
mmol/l
0.05
12
125
6
62
0.97
0.00
1.7
2.8
1553.33
1987.61
ml
—
6
57
6
65
0.92
0.00
1.0
1.0
1829.17
1638.23
miu/ml
—
6
65
7
77
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
0.57
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
50.68
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
35.40
—
0
7
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0
8
87
0.92
-0.00
1.6
1.4
61.00
79.24
umol/l
—
8
87
11
110
1.00
-0.00
1.5
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.04
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
64
640
1.00
-0.00
1.5
1.6
1119.78
961.02
mu/l
0.82
50
522
6
59
1.02
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
69
0.87
-0.00
5.8
6.9
4.58
255.20
ug/l
—
6
47
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.3
—
3.27
%
—
0
11
0
7
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
350.00
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
358.29
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_VERTISTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_VERTISTRAB 0.921 [0.77, 1.09] 0.349
Birth year 0.992 [0.98, 1.0] 0.078

During the follow-up period (1.1.1998 — 31.12.2019), 229 out of 3370 females with H7_VERTISTRAB died.

Males

Parameter HR [95% CI] p-value
H7_VERTISTRAB 1.046 [0.89, 1.23] 0.586
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 2894 males with H7_VERTISTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_VERTISTRAB.

N-year risk Females Males
1 0.086% 0.209%
5 0.507% 1.234%
10 1.248% 2.985%
15 2.428% 5.589%
20 4.468% 9.332%

Relationships between endpoints

Index endpoint: H7_VERTISTRAB – Vertical strabismus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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