retinopathy: Any disease or disorder of the retina.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1569 |
4. Check minimum number of eventsNone |
1569 |
5. Include endpointsNone |
1569 |
6. Filter based on genotype QC (FinnGen only) |
1382 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified retinal disorders
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8708 | 4643 | 4018 |
| Only index persons | 8147 | 4406 | 3741 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.15 | 0.16 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 63.59 | 66.40 | 60.51 |
| Only index persons | 63.65 | 66.36 | 60.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1382 | 750 | 632 |
| Unadjusted period prevalence (%) | 0.28 | 0.27 | 0.29 |
| Median age at first event (years) | 64.38 | 64.41 | 64.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1437
- Matched controls
- 14370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCD20
NOMESCO Finland
Photoangiography of eye
174.9
317.0
156
10
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
467.3
310.8
300
8
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
105.8
310.4
160
17
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
35.7
309.3
198
64
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
20.2
307.7
399
268
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
296.6
307.7
340
15
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
295.2
307.7
245
10
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
20.5
307.7
566
441
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.2
307.7
465
543
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
307.7
766
*
CKC12
NOMESCO Finland
Photocoagulation of retina
148.7
307.7
182
14
H35.9
ICD-10 Finland
Retinal disorder, unspecified
2435.7
307.7
661
5
XCK10
NOMESCO Finland
Photography of fundus of eye
8.4
235.0
359
550
WX140
NOMESCO Finland
Parabulbar anesthesy
16.8
213.7
186
126
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.7
207.9
536
1367
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
54.8
179.0
102
20
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.3
166.6
421
1035
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
66.8
138.3
76
12
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
1295.2
123.9
119
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
12.7
119.9
120
102
H34.8
ICD-10 Finland
Other retinal vascular occlusions
298.5
109.6
110
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
108.7
103
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
17.7
99.4
82
49
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
37.1
91.3
57
16
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
465.6
89.2
88
*
XCK00
NOMESCO Finland
Perimetry
5.5
85.2
180
367
XCH00
NOMESCO Finland
Eye pressure measurement
6.0
76.5
142
256
H33.0
ICD-10 Finland
Retinal detachment with retinal break
766.8
74.9
73
*
H35.36
ICD-10 Finland
Macular cyst
755.7
73.9
72
*
H26.4
ICD-10 Finland
After-cataract
3.8
73.3
255
766
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
160.3
72.7
76
5
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.7
69.6
635
3298
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.1
68.4
213
590
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
66.5
560
2783
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
65.1
62
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
336.8
65.0
65
*
S01ED51
ATC
timolol, combinations; ophthalmic
4.0
61.9
193
534
ZXA10
NOMESCO Finland
Bilateral
2.8
59.9
372
1570
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
131.7
59.3
63
5
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
58.7
56
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
194.1
54.4
56
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
547.8
53.9
53
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.4
53.4
597
3309
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
87.9
53.3
59
7
CKC10
NOMESCO Finland
Local photocoagulation of retina
186.9
52.3
54
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
183.3
51.3
53
*
XCW10
NOMESCO Finland
Assessment of vision
9.9
49.8
58
61
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
49.2
47
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
472.5
46.6
46
*
H35.37
ICD-10 Finland
Macular holes
461.8
45.5
45
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.2
45.4
200
689
37798
ICD-8 Finland
Other diseases of retina and optic nerve, Morbi retinae alii sive NUD
+∞
45.0
43
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.0
44.7
101
216
H20.1
ICD-10 Finland
Chronic iridocyclitis
13.6
43.5
41
31
S01BC03
ATC
diclofenac; ophthalmic
6.6
41.3
68
108
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
40.3
180
623
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
39.7
705
4551
H53.1
ICD-10 Finland
Subjective visual disturbances
3.4
39.6
158
511
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.4
36.1
93
221
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
82.3
36.0
40
5
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
11.9
35.3
36
31
H3601, E113,
ICD-10 Finland
+∞
34.5
33
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.6
34.2
84
192
S01EC01
ATC
acetazolamide; systemic
6.4
33.6
56
90
ZXA00
NOMESCO Finland
Right side
2.1
33.5
447
2561
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
65.0
33.2
38
6
H3600, E113,
ICD-10 Finland
+∞
32.4
31
*
H36.01
ICD-10 Finland
Diabetic maculopathy
73.6
32.0
36
5
S01BC05
ATC
ketorolac; ophthalmic
4.1
31.5
89
227
S01ED01
ATC
timolol; ophthalmic
4.3
30.5
80
193
ZXA05
NOMESCO Finland
Left side
2.0
30.2
411
2358
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.1
27.8
34
38
H26.2
ICD-10 Finland
Complicated cataract
9.4
27.5
33
36
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
27.0
232
1106
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
142.7
26.7
28
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.3
25.1
37
52
H40.0
ICD-10 Finland
Glaucoma suspect
2.7
24.8
147
590
CS494
NOMESCO Finland
Other visual field testing
4.3
24.0
63
152
Z3231
NOMESCO Finland
Registered nurse
1.9
23.9
426
2644
H35.4
ICD-10 Finland
Peripheral retinal degeneration
68.6
23.9
27
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.9
23.4
36
53
H36.00
ICD-10 Finland
Diabetic background retinopathy
84.8
22.7
25
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
21.9
21
*
S01EC04
ATC
brinzolamide; ophthalmic
3.3
21.9
87
279
114
Kela drug reimbursment
Glaucoma
2.4
21.7
161
717
H34.2
ICD-10 Finland
Other retinal artery occlusions
223.3
21.7
22
*
127
Kela drug reimbursment
Transplant complication
6.0
20.9
37
63
S01EE01
ATC
latanoprost; ophthalmic
2.7
20.8
121
480
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.0
20.7
94
326
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
27.5
20.1
27
10
CKC20
NOMESCO Finland
Cryopexy of undetached retina
202.7
19.6
20
*
S01EA05
ATC
brimonidine; ophthalmic
3.9
19.4
58
154
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.0
19.1
54
138
A10AB01
ATC
insulin (human); parenteral
4.7
19.0
44
96
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
18.8
18
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
192.4
18.6
19
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.3
18.2
47
112
L04AA06
ATC
mycophenolic acid; systemic
4.7
18.0
42
92
Z94.0
ICD-10 Finland
Kidney transplant status
7.3
17.8
26
36
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
13.9
17.8
30
22
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
17.7
17
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.1
17.2
47
117
Z2221
NOMESCO Finland
Medical doctor
1.7
17.2
393
2584
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
16.7
16
*
H33.5
ICD-10 Finland
Other retinal detachments
23.3
16.4
23
10
S01EE05
ATC
tafluprost; ophthalmic
3.0
16.1
74
259
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.7
15.8
51
143
A10AA02, ,
ATC
4.3
15.8
40
94
ZXE00
NOMESCO Finland
One hour or less
1.6
15.8
544
3956
H3601, E103,
ICD-10 Finland
+∞
15.6
15
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
15.6
15
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
161.7
15.5
16
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
15.3
504
3617
A10AE04
ATC
insulin glargine; parenteral
2.2
15.3
139
673
3628X
ICD-9 Finland
Other retinal disorders[MORBUS RETINAE ALIA DEFINITA]
+∞
14.6
14
*
A10AC01
ATC
insulin (human); parenteral
2.4
14.6
102
442
WX002
NOMESCO Finland
Sedation and analgesia
1.8
14.5
280
1745
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
14.5
438
3071
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
151.5
14.5
15
*
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
151.5
14.5
15
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
36.4
14.5
18
5
A10AA01, ,
ATC
5.1
14.3
30
60
F05
ICPC
Visual disturbance other
3.1
14.3
60
199
H04AA01
ATC
glucagon; nasal, parenteral
5.7
14.2
26
46
A12AA04
ATC
calcium carbonate; oral
4.5
14.1
34
77
ZX198
NOMESCO Finland
Other local administration
11.0
14.0
26
24
L04AX01
ATC
azathioprine; systemic
2.8
13.9
69
252
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.3
13.8
23
37
A10AE05
ATC
insulin detemir; parenteral
2.7
13.7
76
294
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.8
13.6
41
110
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
13.6
13
*
H3603, E103,
ICD-10 Finland
+∞
13.6
13
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
34.4
13.5
17
5
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
13.4
104
472
T89
ICPC
Diabetes insulin dependent
3.2
13.2
52
166
A10AB05
ATC
insulin aspart; parenteral
2.3
13.1
103
470
H26.02
ICD-10 Finland
Presenil cataract
3.6
13.0
43
123
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
10.2
13.0
25
25
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
28.6
13.0
17
6
H02AB06
ATC
prednisolone; systemic
1.5
12.9
669
5258
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
22.8
12.9
18
8
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
12.7
525
3930
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.8
12.6
28
59
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
12.5
12
*
H3603, E113,
ICD-10 Finland
+∞
12.5
12
*
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
12.5
12
*
H3600, E103,
ICD-10 Finland
+∞
12.5
12
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.4
12.5
25
27
A02BC02
ATC
pantoprazole; systemic
1.5
12.3
961
8186
S01EA03
ATC
apraclonidine; ophthalmic
9.1
12.3
25
28
A11CC03
ATC
alfacalcidol; systemic
3.4
12.2
44
133
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
11.2
12.0
22
20
Z71.8
ICD-10 Finland
Other specified counselling
1.5
12.0
460
3377
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.2
11.9
108
523
N18.8
ICD-10 Finland
Other chronic renal failure
3.4
11.8
43
131
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
19.1
11.6
17
9
H53.4
ICD-10 Finland
Visual field defects
3.5
11.6
39
113
S01EE03
ATC
bimatoprost; ophthalmic
3.2
11.6
45
143
A98
ICPC
Health maint/preventive medicine
2.3
11.6
1363
12769
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
11.6
41
123
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
13.7
11.5
19
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.5
693
5572
ZX120
NOMESCO Finland
Intravenous
1.9
11.2
140
760
L17
ICPC
Foot/toe symptom/complaint
1.5
11.1
432
3173
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
11.1
166
957
N02BE01
ATC
paracetamol; systemic, rectal
1.8
11.0
1263
11565
H44.2
ICD-10 Finland
Degenerative myopia
43.7
10.9
13
*
L04AX03
ATC
methotrexate; systemic
1.9
10.9
141
775
H25.8
ICD-10 Finland
Other senile cataract
1.8
10.9
162
932
ZXD20
NOMESCO Finland
Day surgery
1.8
10.8
175
1033
S01EC03
ATC
dorzolamide; ophthalmic
4.1
10.7
29
72
R42
ICD-10 Finland
Dizziness and giddiness
1.6
10.7
334
2336
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
60.5
10.6
12
*
L04AD02
ATC
tacrolimus; systemic
5.3
10.6
21
40
S01EE04
ATC
travoprost; ophthalmic
3.3
10.4
38
116
1LA05, ,
NOMESCO Finland
+∞
10.4
10
*
AA1AD
NOMESCO Finland
CT of head and brain
1.5
10.4
428
3172
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
9.6
10.3
20
21
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
10.2
275
1858
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
3.7
10.2
31
84
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
10.1
80
366
A10AB04
ATC
insulin lispro; parenteral
3.4
10.0
36
109
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.7
10.0
23
50
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
40.4
10.0
12
*
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.2
9.8
20
39
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
9.8
74
332
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
9.8
158
931
H52.1
ICD-10 Finland
Myopia
2.8
9.7
49
181
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
9.7
30
82
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.7
249
1662
CKA10
NOMESCO Finland
Biopsy of vitreous body
55.4
9.7
11
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.3
9.6
19
36
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
9.5
123
676
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.4
470
3606
C08CA01
ATC
amlodipine; oral
1.4
9.4
558
4419
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
9.4
9
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
9.4
9
*
H31.8
ICD-10 Finland
Other specified disorders of choroid
+∞
9.4
9
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
9.4
9
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
9.4
9
*
CK2Z4
NOMESCO Finland
Ocular fundus light imaging (OCT), angiography
+∞
9.4
9
*
L28
ICPC
Limited function/disability (L)
1.6
9.3
283
1960
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
9.3
102
531
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
9.2
311
2205
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
18.7
8.9
13
7
B01AC04
ATC
clopidogrel; oral
1.6
8.9
240
1616
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
24.2
8.9
12
5
L04AD01
ATC
ciclosporin; systemic
3.6
8.9
28
78
137
Kela drug reimbursment
Uraemia requiring dialysis
6.9
8.8
21
31
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
8.8
326
2352
Z31.5
ICD-10 Finland
Genetic counselling
2.3
8.7
68
310
H35
ICD-10 Finland
Other retinal disorders
50.3
8.7
10
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.7
174
1089
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
8.7
96
501
A10AD01
ATC
insulin (human); parenteral
4.4
8.6
21
48
TK800
NOMESCO Finland
Hemodialysis
3.1
8.6
36
120
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
8.6
161
989
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.7
8.5
45
171
UJF32
NOMESCO Finland
Coloscopy
1.5
8.5
354
2617
N02AX02
ATC
tramadol; systemic, rectal
1.4
8.5
585
4735
B05DA
ATC
Isotonic solutions
7.4
8.5
19
26
A28
ICPC
Limited function/disability NOS
1.5
8.4
272
1906
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
8.3
8
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
8.3
8
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
8.3
8
*
B05DB
ATC
Hypertonic solutions
8.6
8.3
17
20
H20.8
ICD-10 Finland
Other iridocyclitis
9.5
8.3
16
17
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
8.3
867
7506
H54.7
ICD-10 Finland
Unspecified visual loss
6.5
8.2
20
31
Z49.2
ICD-10 Finland
Other dialysis
7.6
8.2
18
24
H47.1
ICD-10 Finland
Papilloedema, unspecified
9.0
8.0
16
18
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.1
8.0
15
15
CHC05
NOMESCO Finland
Iridotomy
3.6
8.0
26
74
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
942
8296
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.9
181
1170
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.9
175
1122
H26.8
ICD-10 Finland
Other specified cataract
4.5
7.9
19
43
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
7.9
115
657
J01MA14
ATC
moxifloxacin; systemic
1.8
7.8
124
726
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.8
7.8
23
61
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
7.8
62
285
M79.6
ICD-10 Finland
Pain in limb
1.4
7.8
592
4847
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
10.9
7.8
14
13
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
7.8
89
470
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.7
219
1491
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.3
7.7
28
86
XCH05
NOMESCO Finland
Eye pressure longterm registration
4.5
7.7
18
40
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.7
476
3769
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.1
7.6
70
341
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.5
7.6
45
181
J01DB01
ATC
cefalexin; oral
1.4
7.6
1111
10098
CA1ME
NOMESCO Finland
Ultrasound oculometry
6.7
7.6
18
27
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
25.1
7.6
10
*
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
25.1
7.6
10
*
A04
ICPC
Weakness/tiredness general
1.5
7.6
217
1480
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.5
839
7284
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.5
331
2467
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
7.5
126
752
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
7.4
56
253
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.0
7.4
20
50
WX142
NOMESCO Finland
Sub-tenon anesthesy
8.4
7.3
15
18
F29
ICPC
Eye symptom/complaint other
1.7
7.3
141
873
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
7.3
7
*
1LA01, ,
NOMESCO Finland
+∞
7.3
7
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
7.3
7
*
H3602, E113,
ICD-10 Finland
+∞
7.3
7
*
1LA04, ,
NOMESCO Finland
+∞
7.3
7
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
7.3
554
4526
C10AA05
ATC
atorvastatin; oral
1.4
7.2
581
4783
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.2
338
2542
U07
ICPC
Urine symptom/complaint other
1.7
7.2
120
713
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
7.2
347
2623
V03AE01
ATC
polystyrene sulfonate; oral
3.7
7.2
22
60
R05
ICD-10 Finland
Cough
1.5
7.2
277
2009
R4110
NOMESCO Finland
Physiotherapy
1.4
7.2
370
2833
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
30.2
7.2
9
*
D31.2
ICD-10 Finland
Benign neoplasm: Retina
30.2
7.2
9
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
12.1
7.1
12
10
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.1
130
795
U02
ICPC
Urinary frequency/urgency
1.5
7.0
205
1402
R05
ICPC
Cough
1.4
7.0
324
2433
CKD60
NOMESCO Finland
Anterior vitrectomy
5.9
6.9
18
31
N03AX16
ATC
[U] pregabalin
1.4
6.9
299
2215
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.9
522
4249
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
8.3
6.8
14
17
P01BA02
ATC
hydroxychloroquine; oral
1.8
6.8
106
618
C09CA06
ATC
candesartan; oral
1.4
6.8
319
2398
H40.11
ICD-10 Finland
Low pressure glaucoma
2.6
6.7
37
144
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.3
6.7
24
73
H02
ICPC
Hearing complaint
1.5
6.7
207
1434
SPAT1263
SPAT
Sampling
1.4
6.7
525
4295
H57.1
ICD-10 Finland
Ocular pain
2.2
6.7
54
251
Z3226
NOMESCO Finland
Physiotherapist
1.5
6.6
238
1703
SFA10
NOMESCO Finland
One-surface restoration
1.3
6.5
685
5840
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.7
6.5
33
123
XQ902
NOMESCO Finland
Other photography
3.7
6.5
20
55
R51.80
ICD-10 Finland
Headache
1.5
6.4
194
1339
U08
ICPC
Urinary retention
2.7
6.4
32
119
Z2446
NOMESCO Finland
Social worker
1.8
6.4
86
481
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.3
380
2975
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.3
342
2633
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.3
287
2146
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
6.3
6
*
M05BA04
ATC
alendronic acid; oral
1.6
6.2
127
798
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
26.8
6.2
8
*
A01
ICPC
Pain general/multiple sites
1.6
6.2
143
926
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.2
152
1000
E0000UV, ,
ATC
1.3
6.2
521
4296
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
2.6
6.2
33
127
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
6.2
147
961
Z2445
NOMESCO Finland
Psychologist
2.2
6.1
48
220
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.1
210
1485
B01AB05
ATC
enoxaparin; parenteral
1.4
6.1
413
3291
R35
ICD-10 Finland
Polyuria
1.8
6.1
93
539
S01BA01
ATC
dexamethasone; ophthalmic
2.2
6.1
47
214
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.1
212
1506
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
8.6
6.1
12
14
J01FF01
ATC
clindamycin; systemic
1.4
6.1
341
2640
C08CA13
ATC
lercanidipine; oral
1.5
6.0
202
1422
H21.0
ICD-10 Finland
Hyphaema
10.1
6.0
11
11
I72.8
ICD-10 Finland
Aneurysm and dissection of other specified arteries
10.1
6.0
11
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.0
139
901
F99
ICPC
Eye/adnexa disease other
5.2
6.0
17
33
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.3
6.0
22
68
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
6.0
84
475
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
60
7.36
29.35
1.9
3.0
672.05
1040.22
u/ml
0.87
43
60
147
545
2.89
28.90
2.0
2.0
40.34
38.68
u/l
0.44
132
487
982
7615
1.91
27.94
7.1
5.2
6.89
6.68
mmol/l
2.26
938
7257
805
5920
1.82
26.50
6.9
5.0
35.82
35.41
g/l
1.38
756
5564
882
6729
1.80
25.06
11.0
7.3
1.21
1.21
mmol/l
0.04
798
5809
941
7347
1.81
24.43
12.6
9.7
4.29
4.16
e9/l
0.63
823
6367
804
6066
1.74
22.77
9.6
6.6
1.21
1.21
mmol/l
0.13
761
5608
54
122
4.56
22.33
2.3
2.5
11.72
54.77
iu/ml
—
6
16
596
4186
1.72
21.45
2.8
2.2
205.40
234.96
u/l
0.25
568
3976
673
4894
1.71
21.26
5.5
4.1
142.82
116.13
e6/l
0.12
489
3472
1109
9276
1.86
21.02
5.9
4.4
13.46
12.82
mm/h
0.74
1053
8655
1147
9717
1.89
20.60
11.3
8.4
81.99
79.41
u/l
0.84
1097
9231
81
265
3.18
19.75
9.0
5.6
1001.52
607.44
iu/ml
0.23
21
36
53
132
4.13
19.36
1.2
1.1
—
—
—
0
0
796
6171
1.65
18.79
19.1
16.3
1.29
1.28
inr
0.37
693
5141
1333
12028
2.50
18.71
24.7
17.1
22.42
25.65
mg/l
3.90
1129
10016
1009
8348
1.70
18.20
6.1
5.0
349.15
1645.50
e6/l
1.35
20
125
366
2329
1.77
18.12
3.7
3.1
1.09
1.25
e6/l
0.24
219
1242
596
4327
1.64
18.02
4.6
3.5
32.66
74.12
e6/l
1.60
463
3313
755
5820
1.63
17.86
3.0
2.4
78.85
78.53
nmol/l
0.11
689
5219
36
72
5.10
17.20
2.9
2.5
207.24
222.67
e6/l
0.17
29
66
858
6862
1.62
17.16
8.1
6.8
11.75
11.72
umol/l
0.02
825
6559
389
2553
1.72
17.12
4.8
4.1
564.10
405.67
ng/l
0.28
310
2061
53
145
3.76
17.03
2.2
2.0
10640.00
1931.43
titre
—
5
7
1353
12377
2.59
16.88
29.5
20.7
3.98
3.98
mmol/l
0.03
1333
12123
477
3317
1.66
16.81
6.3
4.2
89.22
88.49
%
0.25
466
3250
1351
12359
2.56
16.70
29.0
20.5
139.55
139.63
mmol/l
0.52
1333
12122
441
3021
1.66
16.40
3.6
2.7
5.58
5.86
e6/l
0.10
399
2751
1279
11469
2.05
16.26
8.1
6.4
40.40
39.24
mmol/mol
4.34
1209
10682
35
72
4.96
16.20
2.8
2.2
516.69
636.56
e6/l
0.36
26
62
1261
11257
1.98
16.16
6.1
5.4
2.02
1.95
mu/l
0.84
1180
10383
1370
12643
2.79
16.12
17.5
12.5
27.33
25.97
u/l
0.92
1339
12273
848
6836
1.59
15.78
5.1
4.0
0.03
0.23
estimate
0.44
153
1373
1377
12765
2.89
15.58
31.4
22.5
84.68
78.72
umol/l
3.88
1366
12604
833
6719
1.57
15.20
5.1
4.0
0.00
0.00
estimate
-0.00
158
1422
840
6793
1.57
15.12
5.1
4.0
0.00
4.27
estimate
1.34
158
1461
331
2141
1.71
15.11
3.7
3.2
2.10
2.41
e6/l
0.39
177
1050
1136
9923
1.69
14.40
30.2
21.2
13.81
13.71
%
1.65
1119
9792
26
46
5.74
14.17
26.1
32.2
108.05
131.73
ug/l
1.03
19
37
319
2077
1.69
14.10
2.9
2.0
29.26
29.70
s
0.67
314
2021
84
349
2.49
13.13
2.3
2.2
13.99
12.14
mg/l
0.74
79
324
504
3729
1.54
12.92
4.3
3.4
0.39
0.41
e6/l
0.05
375
2742
89
385
2.40
12.76
1.5
1.5
1.30
19.45
iu/ml
0.45
20
62
180
1023
1.87
12.60
3.6
2.8
61.58
64.79
ml/min/173m2
0.43
65
451
317
2116
1.64
12.57
4.0
2.6
2.29
2.29
g/l
0.02
290
1959
556
4232
1.51
12.34
3.3
3.2
2123.33
1436.25
ng/l
0.92
490
3648
1384
13017
2.71
12.29
37.2
26.0
6.80
6.76
e9/l
0.18
1360
12710
224
1370
1.75
12.29
8.3
3.4
1.55
1.96
mmol/l
1.04
201
1174
1083
9477
1.58
12.21
4.9
4.3
14.86
14.90
pmol/l
0.24
1002
8675
49
159
3.16
12.17
1.2
1.2
4.03
6.06
u/ml
0.46
29
71
1383
13010
2.68
12.15
37.3
25.9
245.18
248.05
e9/l
0.92
1364
12742
1383
13013
2.67
12.09
37.1
25.9
91.36
91.34
fl
0.05
1372
12871
1383
13015
2.67
12.05
37.9
26.4
39.85
40.47
%
0.98
1372
12866
1383
13015
2.67
12.05
37.2
25.9
4.42
4.46
e12/l
1.83
1357
12712
599
4649
1.49
12.01
3.5
3.5
2.35
2.36
mmol/l
0.22
557
4202
1383
13018
2.66
11.99
37.5
26.1
133.05
134.41
g/l
2.72
1372
12877
953
8124
1.51
11.98
4.1
3.4
59.59
50.33
u/l
1.32
911
7633
295
1967
1.63
11.66
4.0
2.6
21.32
22.53
%
0.84
275
1833
106
516
2.14
11.49
2.5
1.9
10.28
8.29
iu/ml
0.21
23
119
147
806
1.92
11.46
2.6
2.6
18.53
22.16
au/ml
0.22
17
74
1268
11602
1.79
11.39
23.1
16.8
76.70
78.92
ml/min/173m2
3.10
1209
10782
247
1586
1.67
11.29
5.7
4.4
230.97
252.06
u/l
1.96
233
1498
278
1841
1.63
11.26
11.7
5.6
1.05
1.03
mmol/l
0.63
263
1697
136
735
1.94
11.07
1.4
1.4
29.50
55.26
au/ml
—
6
48
693
5597
1.46
11.05
15.2
11.9
0.00
0.00
e9/l
0.67
563
4568
194
1175
1.75
10.96
3.2
2.9
66.67
66.54
g/l
0.08
174
1084
1287
11856
1.82
10.91
6.0
5.1
4.42
4.60
mmol/l
8.17
1210
11027
47
159
3.02
10.91
1.1
1.1
—
—
—
0
0
170
992
1.81
10.89
3.5
2.9
10.26
10.78
g/l
0.87
160
912
183
1092
1.77
10.88
3.2
3.1
220.64
214.43
ng/l
0.08
159
1012
1305
12077
1.88
10.84
6.9
5.9
2.53
2.67
mmol/l
7.19
1222
11177
1282
11803
1.80
10.80
5.9
5.0
1.45
1.46
mmol/l
0.52
1196
10901
192
1169
1.74
10.64
2.8
2.4
5.53
7.23
ug/l
0.91
172
1034
252
1650
1.64
10.63
7.5
8.0
4.96
5.12
kpa
1.72
239
1590
725
5933
1.45
10.62
2.4
2.2
92.08
95.46
pmol/l
1.11
378
3091
231
1481
1.67
10.58
4.6
2.8
11.11
8.34
umol/l
0.77
193
1308
327
2285
1.56
10.48
4.1
2.6
11.98
12.68
umol/l
1.04
304
2130
251
1651
1.63
10.38
7.5
8.0
12.68
12.11
kpa
0.78
238
1596
573
4506
1.45
10.28
4.3
3.3
6.83
7.53
mmol/l
3.92
508
3827
45
154
2.98
10.25
1.1
1.1
116.44
118.28
%
0.12
39
141
558
4369
1.45
10.23
5.2
4.0
12.25
7.57
mg/mmol
1.04
384
2726
249
1641
1.63
10.21
7.4
8.0
0.34
1.04
mmol/l
1.92
207
1357
122
655
1.94
10.12
2.4
1.8
1.45
1.61
g/l
0.93
108
567
184
1124
1.73
10.06
3.5
2.4
0.61
0.50
e6/l
0.24
175
1071
705
5779
1.43
10.01
4.6
3.0
139.91
134.89
ug/l
0.16
654
5366
55
213
2.65
9.98
2.2
1.4
118.91
154.71
au/ml
0.85
15
57
29
76
3.87
9.97
2.6
2.0
—
—
—
0
0
175
1060
1.74
9.85
6.2
3.8
102.84
88.94
ng/l
0.77
153
914
200
1257
1.69
9.84
13.8
6.9
11.14
10.08
mmol/l
1.26
193
1203
226
1473
1.63
9.66
7.6
8.3
95.31
95.46
%
0.11
218
1428
196
1232
1.68
9.64
4.4
2.6
69.10
68.62
e9/l
0.06
138
894
27
69
3.97
9.61
2.1
1.4
—
—
—
0
0
27
69
3.97
9.61
2.1
1.4
—
—
—
0
0
459
3501
1.46
9.50
2.8
2.2
2.96
2.88
mg/l
0.20
399
2988
103
535
2.00
9.40
2.7
2.6
2.80
2.98
g/l
0.95
93
487
535
4213
1.43
9.27
4.7
3.2
36.49
33.35
u/l
0.72
508
3984
197
1253
1.66
9.25
3.2
2.5
43.12
41.10
u/l
0.10
168
1063
211
1366
1.64
9.24
8.3
8.8
118.23
120.98
g/l
1.19
205
1338
46
170
2.76
9.15
1.2
1.2
2.48
3.71
u/ml
0.33
21
56
107
572
1.94
9.00
2.6
2.6
7.34
7.46
g/l
0.33
97
524
52
207
2.57
8.95
5.6
3.1
158.00
1394.39
u/ml
—
6
23
521
4110
1.42
8.84
3.5
2.6
54.58
81.50
u/l
0.77
485
3812
321
2310
1.50
8.81
5.1
3.2
0.82
0.82
mmol/l
0.07
301
2175
1266
11743
1.66
8.72
6.1
5.3
6.09
5.95
mmol/l
2.64
1176
10736
106
572
1.92
8.68
2.6
2.6
4.09
4.22
g/l
1.00
97
524
106
572
1.92
8.68
2.6
2.5
3.61
3.70
g/l
0.27
97
524
1226
11291
1.58
8.62
5.1
4.3
1.29
1.29
mmol/l
0.02
1145
10329
331
2431
1.47
8.14
1.7
1.5
2.24
2.50
g/l
1.76
201
1462
246
1704
1.54
8.02
2.2
1.9
—
—
—
0
0
257
1802
1.52
7.92
2.2
1.9
—
—
—
0
0
819
7063
1.37
7.77
2.9
2.9
—
—
—
0
0
394
3016
1.42
7.71
5.5
4.2
1.02
1.52
kg/l
0.50
283
2002
366
2765
1.43
7.70
2.9
3.0
2.46
2.46
mmol/l
0.07
330
2485
367
2794
1.42
7.36
2.6
1.7
1.13
1.30
mg/l
0.74
293
2174
140
866
1.68
7.29
7.4
6.6
23.93
24.47
mmol/l
1.14
132
830
52
229
2.32
7.26
1.5
1.2
305.45
252.67
u/ml
0.68
38
130
118
698
1.75
7.22
3.0
3.6
4.35
4.53
pmol/l
1.13
104
616
416
3246
1.40
7.22
3.2
2.5
—
—
—
0
0
488
3921
1.37
7.05
1.9
1.7
22.18
20.13
nmol/l
1.97
418
3291
18
43
4.23
7.02
3.8
2.9
0.59
0.60
mmol/l
0.08
18
43
703
5983
1.34
6.94
3.6
2.9
—
—
estimate
—
0
0
91
505
1.86
6.88
2.7
2.6
9.86
10.48
g/l
0.90
81
453
426
3360
1.38
6.87
3.6
2.8
346.82
346.65
umol/l
0.01
385
2967
610
5104
1.34
6.67
4.2
4.0
87.79
71.74
ng/l
0.12
465
3756
308
2309
1.43
6.65
1.8
1.8
1161.50
1181.39
nmol/l
0.12
245
1717
18
34
5.35
6.47
1.2
1.0
—
—
—
0
0
35
136
2.61
6.40
1.3
1.2
—
—
—
0
0
73
387
1.93
6.36
4.9
2.3
3.58
3.59
g/l
0.02
68
371
88
497
1.82
6.31
3.0
2.8
0.74
1.30
g/l
0.88
77
433
19
52
3.69
6.21
1.3
1.1
1536.63
1457.29
miu/ml
0.10
19
52
67
348
1.97
6.19
1.2
1.2
1.92
11.29
u/ml
—
5
56
355
2760
1.38
6.15
1.4
1.3
3.48
1.54
u/ml
0.84
95
740
216
1539
1.47
6.08
2.3
2.4
148.57
129.80
ug/g
0.26
170
1242
36
149
2.45
5.81
1.3
1.4
0.20
0.19
nmol/l
0.21
26
119
311
2388
1.39
5.78
2.4
2.0
—
—
—
0
0
83
479
1.78
5.57
1.4
1.2
0.39
0.98
u/ml
—
9
34
70
384
1.87
5.53
8.9
3.0
1.71
1.61
mg/l
0.45
65
349
10
10
10.06
5.53
1.0
1.2
—
—
—
0
0
301
2315
1.38
5.51
1.3
1.3
47.69
33.31
iu/ml
0.68
98
710
459
3777
1.32
5.34
5.4
4.2
0.00
0.00
estimate
0.96
141
1325
40
181
2.24
5.32
1.2
1.1
—
19.00
—
0
8
594
5066
1.29
5.28
5.0
4.0
0.00
0.04
estimate
1.28
133
1171
150
1024
1.52
5.19
2.2
1.6
—
—
—
0
0
173
1221
1.47
5.10
2.3
2.1
397.43
383.73
nmol/l
0.44
161
1126
49
245
2.04
5.08
1.7
1.3
208.00
515.79
titre
—
5
19
133
891
1.54
5.03
5.4
2.8
126.83
128.01
g/l
0.24
127
866
129
859
1.55
5.01
8.2
10.2
24.03
24.41
mmol/l
0.64
123
844
21
71
2.99
4.99
1.0
1.1
11.30
8.47
iu/ml
—
5
20
120
794
1.56
4.80
10.9
10.5
15.81
15.87
%
0.09
114
767
21
74
2.87
4.66
1.3
1.2
—
—
—
0
0
276
2164
1.34
4.40
1.3
1.3
19.47
13.24
u/ml
0.55
107
796
72
430
1.71
4.35
3.1
2.6
0.01
0.02
g/l
0.39
65
388
15
45
3.36
4.33
3.1
1.4
2.13
1.99
umol/l
0.32
15
38
67
397
1.72
4.17
3.2
2.7
0.00
0.00
g/l
-0.00
62
372
79
490
1.65
4.16
3.5
3.6
39.73
61.79
mg/l
1.06
72
422
79
490
1.65
4.16
3.5
3.6
30.07
67.63
mg/l
0.94
71
421
57
328
1.77
3.94
1.7
1.6
—
—
—
0
0
129
908
1.46
3.88
1.9
1.7
—
—
—
0
0
69
423
1.66
3.82
3.2
2.6
0.00
0.00
g/l
-0.00
62
373
17
60
2.86
3.80
1.3
1.1
—
—
—
0
0
482
4133
1.25
3.79
5.6
5.5
2.36
2.61
ug/l
0.28
440
3732
176
1317
1.38
3.77
2.8
2.2
0.21
0.21
g/l
0.09
166
1229
51
289
1.79
3.73
1.3
1.3
—
—
—
0
0
51
289
1.79
3.73
1.3
1.3
—
—
—
0
0
111
765
1.49
3.72
5.8
2.4
1.12
1.21
%
0.58
111
760
582
5108
1.23
3.67
2.0
1.9
1.31
1.36
mmol/l
0.98
501
4295
9
16
5.65
3.66
1.8
2.3
—
—
—
0
0
333
2750
1.27
3.58
1.9
1.7
21661123.91
22436893.91
pmol/l
0.01
277
2282
54
317
1.73
3.52
2.3
1.3
448.25
558.44
mg/l
1.75
48
299
15
52
2.90
3.47
1.2
1.1
473.73
189.65
iu/ml
0.93
15
52
72
461
1.59
3.39
1.5
1.3
—
—
—
0
0
35
182
1.95
3.35
1.2
1.6
—
—
—
0
0
16
60
2.69
3.23
1.2
2.0
—
—
—
0
0
12
34
3.55
3.20
1.3
1.1
—
—
—
0
0
68
439
1.58
3.11
3.5
3.6
13.83
3.43
ratio
0.61
43
244
10
25
4.02
3.08
2.9
1.4
—
—
—
0
0
76
505
1.53
3.07
3.0
2.8
—
—
—
0
0
60
378
1.61
3.04
1.9
1.7
—
—
—
0
0
53
324
1.66
3.02
1.8
1.9
5.41
21.16
iu/l
0.44
23
134
29
149
1.97
2.91
1.3
1.4
—
—
—
0
0
386
3313
1.23
2.89
4.7
4.5
21.76
21.39
%
0.21
186
1613
45
267
1.71
2.88
2.9
2.3
106.96
124.08
ug/min
0.12
29
164
46
275
1.69
2.86
2.3
1.4
14.89
70.38
e6/l
1.05
35
202
37
208
1.80
2.84
1.3
1.3
—
—
—
0
0
21
96
2.21
2.84
1.3
1.1
—
—
—
0
0
46
278
1.68
2.76
2.3
1.5
253.78
669.29
e6/l
0.43
37
214
58
372
1.58
2.76
1.4
1.3
—
—
—
0
0
61
397
1.56
2.73
1.4
1.5
230.78
277.26
ug/g
1.11
34
234
21
99
2.14
2.65
1.3
1.1
—
—
—
0
0
21
99
2.14
2.65
1.3
1.1
—
—
—
0
0
22
106
2.09
2.63
1.3
1.1
—
—
—
0
0
46
283
1.65
2.60
2.3
1.2
3.72
3.71
mmol/l
0.01
41
266
48
299
1.63
2.59
1.3
1.1
7.82
3.88
—
5
38
23
114
2.03
2.57
1.2
1.1
—
55.11
—
0
9
12
42
2.87
2.55
1.3
1.4
129.75
173.68
mmol/24h
0.98
12
42
187
1499
1.28
2.54
9.4
7.2
—
—
—
0
0
29
157
1.86
2.53
1.2
1.1
1.69
1.95
—
5
27
182
1456
1.29
2.51
3.6
4.3
14.08
16.13
ug/l
0.09
145
1198
16
69
2.33
2.48
1.4
1.2
30.88
24.20
u/l
0.22
16
64
45
279
1.63
2.48
9.1
7.0
104.26
105.58
mmol/l
0.75
39
253
17
76
2.25
2.44
1.9
2.2
—
—
—
0
0
20
96
2.10
2.43
1.4
1.1
—
—
—
0
0
16
70
2.30
2.41
1.3
1.1
1.01
1.22
u/l
—
7
40
85
610
1.42
2.40
2.4
1.9
1.66
1.53
ug/l
0.08
76
546
19
90
2.13
2.39
2.9
2.3
645.42
608.05
ml
0.18
12
63
14
58
2.43
2.37
1.3
1.2
—
—
—
0
0
14
58
2.43
2.37
1.1
1.2
—
—
—
0
0
8
22
3.65
2.36
1.0
1.0
16.48
57.52
iu/ml
—
8
22
9
28
3.23
2.31
1.4
1.0
—
—
—
0
0
26
144
1.82
2.15
1.3
1.3
276.94
277.30
mosm/kgh2o
0.02
18
105
17
81
2.11
2.13
1.8
1.6
111.36
96.77
ng/l
0.47
17
81
68
480
1.44
2.13
3.7
2.7
23.97
24.78
mmol/l
1.08
68
473
86
635
1.38
2.09
6.9
4.8
1.59
1.56
%
0.10
78
599
79
575
1.40
2.09
1.1
1.0
—
—
—
0
0
126
988
1.30
2.05
1.6
1.4
—
—
—
0
0
104
794
1.33
2.05
1.2
1.2
131.61
129.83
u/ml
0.02
29
306
6
15
4.01
2.04
1.2
1.3
—
—
—
0
0
101
770
1.34
2.01
3.5
3.7
1.83
2.01
mmol/l
0.24
73
575
61
427
1.45
2.01
1.6
1.6
20.56
14.66
u/ml
0.33
13
97
75
547
1.39
1.97
2.3
3.3
1289.08
2733.57
u/ml
0.33
62
483
22
119
1.86
1.97
1.3
1.2
—
—
—
0
0
224
1891
1.22
1.95
1.6
1.5
—
—
—
0
0
7
22
3.19
1.88
1.0
1.0
—
—
—
0
0
5
12
4.18
1.82
1.2
1.0
128.00
77.33
titre
—
5
12
17
87
1.97
1.80
1.3
1.2
—
—
—
0
0
42
280
1.52
1.78
1.8
2.0
213.93
211.30
pmol/l
0.06
42
265
47
321
1.48
1.78
1.3
1.3
—
—
—
0
0
19
102
1.87
1.76
1.6
1.1
127.89
104.18
pmol/l
0.93
19
102
15
74
2.04
1.75
1.5
1.1
—
—
—
0
0
21
117
1.81
1.74
1.3
1.2
—
—
—
0
0
45
306
1.49
1.74
1.7
1.6
—
—
—
0
0
20
110
1.83
1.73
1.1
1.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
63
459
1.39
1.70
2.6
2.7
0.29
0.36
iu/ml
0.77
28
248
43
292
1.49
1.68
1.7
1.5
10.44
9.01
u/l
0.18
33
228
22
126
1.76
1.68
1.5
1.6
—
—
—
0
0
24
142
1.70
1.65
4.5
4.0
—
—
—
0
0
57
411
1.40
1.64
1.8
1.7
—
—
—
0
0
11
49
2.25
1.63
1.1
1.2
—
—
—
0
0
19
105
1.82
1.63
3.1
2.4
13.06
7.79
umol/l
0.54
14
71
26
158
1.66
1.63
1.5
1.4
35672.71
32654.10
e6/l
0.07
14
84
50
356
1.42
1.56
1.5
1.6
14787.05
14786.20
e6/l
0.00
39
254
21
122
1.73
1.55
2.0
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
14
71
1.98
1.54
1.3
1.2
—
—
—
0
0
23
138
1.68
1.52
1.4
1.7
21.13
33.44
ng/l
0.77
23
138
23
138
1.68
1.52
3.4
1.8
—
—
—
0
0
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
13
65
2.01
1.49
1.5
1.4
0.53
1.29
nmol/l
—
7
47
69
525
1.33
1.46
1.4
1.7
0.38
0.33
mg/l
0.25
41
251
7
28
2.51
1.45
1.0
1.2
—
—
—
0
0
51
370
1.39
1.45
3.3
3.3
1.88
2.25
index
0.14
25
193
28
180
1.57
1.43
1.5
1.4
1225.58
1686.44
e6/l
0.31
19
123
162
1370
1.21
1.42
3.3
3.6
—
—
—
0
0
7
29
2.42
1.39
1.0
1.1
—
—
—
0
0
14
74
1.90
1.39
1.2
1.2
91.79
77.10
u/l
0.22
14
68
11
53
2.08
1.38
2.5
1.9
39.78
40.42
g/l
0.11
11
53
13
67
1.95
1.38
3.7
3.9
—
—
—
0
0
5
17
2.95
1.36
1.2
1.2
—
—
—
0
0
10
47
2.14
1.33
1.0
1.0
—
—
—
0
0
16
90
1.79
1.33
4.3
1.9
—
—
—
0
0
45
326
1.39
1.31
1.3
1.3
285.01
237.37
miu/ml
0.31
20
144
20
121
1.66
1.31
1.4
1.3
—
—
—
0
0
278
2478
1.15
1.31
3.0
3.3
0.71
0.76
ug/l
0.57
189
1623
14
76
1.85
1.30
1.3
1.1
—
—
—
0
0
24
153
1.58
1.29
3.4
1.7
—
—
—
0
0
5
18
2.78
1.28
2.8
1.4
—
—
—
0
0
12
62
1.94
1.28
1.2
1.7
—
1224609.80
—
0
5
9
44
2.05
1.27
1.2
1.2
—
—
—
0
0
37
261
1.43
1.25
1.7
1.5
—
—
—
0
0
29
196
1.49
1.22
1.3
1.1
—
—
—
0
0
5
19
2.64
1.21
5.4
1.3
—
—
—
0
0
48
357
1.36
1.21
1.2
1.1
—
—
—
0
0
25
164
1.53
1.20
1.3
1.5
—
—
—
0
0
8
38
2.11
1.18
1.1
1.2
—
—
—
0
0
48
359
1.35
1.18
1.2
1.1
—
—
—
0
0
388
3560
1.12
1.17
4.4
3.5
0.08
0.03
estimate
0.24
129
1124
10
50
2.01
1.16
1.0
1.9
—
—
—
0
0
25
166
1.51
1.15
1.3
1.5
1.01
0.96
ratio
0.14
17
106
25
166
1.51
1.15
1.3
1.5
1.24
1.26
ratio
0.04
18
106
25
166
1.51
1.15
1.3
1.5
1.07
1.16
ratio
0.23
17
106
88
722
1.23
1.09
1.6
1.5
—
—
—
0
0
9
46
1.96
1.03
2.4
3.0
8.56
10.18
kpa
—
9
46
9
46
1.96
1.03
2.4
3.0
4.64
4.75
kpa
—
9
46
5
22
2.28
1.03
4.0
2.2
12.06
17.63
umol/l
—
5
22
15
91
1.66
1.00
1.5
2.4
9.54
8.58
mmol/l
0.29
15
91
15
91
1.66
1.00
1.0
1.0
61.66
36.40
ng/l
—
8
56
15
91
1.66
1.00
1.0
1.0
1017.00
683.98
ng/l
—
7
56
15
91
1.66
1.00
1.0
1.0
450.56
262.00
ng/l
—
9
58
15
91
1.66
1.00
1.1
1.2
—
—
—
0
0
121
1034
1.19
1.00
2.6
2.4
12.81
13.12
nmol/l
0.15
112
941
7
35
2.00
1.00
1.6
1.1
—
—
—
0
0
40
300
1.34
0.99
1.8
1.5
—
—
—
0
0
15
92
1.64
0.97
1.1
1.2
—
—
—
0
0
10
54
1.86
0.96
1.6
1.1
64.60
377.27
ng/l
—
5
11
7
37
1.90
0.94
1.6
1.1
—
—
—
0
0
54
427
1.27
0.94
1.6
1.4
31.08
28.82
iu/l
0.18
45
355
33
243
1.37
0.93
3.5
1.5
0.72
0.91
nmol/l
0.76
26
202
25
175
1.44
0.93
1.4
1.6
68.42
61.57
ug/l
0.20
20
150
66
536
1.24
0.92
3.2
2.0
—
—
—
0
0
124
1075
1.17
0.89
4.3
3.9
1.23
1.23
mmol/l
0.34
106
934
19
127
1.50
0.88
3.5
1.6
—
—
—
0
0
19
127
1.50
0.88
3.5
1.6
—
—
—
0
0
19
127
1.50
0.88
3.5
1.6
—
—
—
0
0
125
1085
1.17
0.88
1.9
2.1
3.37
3.54
ratio
0.89
96
864
15
95
1.59
0.87
1.8
1.6
1.03
1.09
promille
0.06
15
72
21
145
1.45
0.85
1.6
1.6
52.14
63.00
%
0.58
14
94
138
1566
0.87
0.84
5.2
4.9
34.75
32.49
%
1.58
100
1012
6
111
0.54
0.83
2.5
1.6
—
—
—
0
0
47
373
1.27
0.82
2.9
1.7
—
—
—
0
0
55
447
1.24
0.79
3.4
1.9
—
—
—
0
0
6
33
1.82
0.79
4.2
3.1
3.83
858.82
ug/l
—
6
33
16
106
1.52
0.79
1.4
1.4
12.19
13.18
u/l
0.24
16
99
42
331
1.28
0.78
2.6
2.2
129.70
127.25
g/l
0.25
37
262
6
34
1.77
0.76
1.7
1.1
—
—
—
0
0
10
59
1.70
0.76
2.5
2.3
34.26
47.77
umol/l
—
10
48
35
271
1.30
0.75
1.8
2.2
875.64
4757.03
u/l
—
9
110
7
39
1.80
0.72
1.6
1.2
—
—
—
0
0
45
362
1.25
0.72
2.9
1.6
—
—
—
0
0
9
57
1.58
0.71
1.6
1.4
—
—
—
0
0
18
126
1.43
0.70
1.2
1.1
—
—
—
0
0
68
574
1.19
0.70
1.3
1.3
—
—
—
0
0
46
375
1.23
0.67
1.4
1.4
—
—
—
0
0
11
70
1.58
0.65
4.6
1.7
—
—
—
0
0
11
70
1.58
0.65
4.6
1.7
—
—
—
0
0
11
70
1.58
0.65
4.6
1.7
—
—
—
0
0
11
70
1.58
0.65
4.6
1.7
—
—
—
0
0
10
63
1.59
0.62
7.9
4.1
1.50
1.22
%
—
10
63
31
244
1.28
0.61
1.6
1.2
18.75
42.91
u/l
1.63
25
215
38
307
1.24
0.61
2.0
1.5
—
—
—
0
0
8
50
1.60
0.61
1.5
1.6
—
—
—
0
0
12
80
1.50
0.60
1.2
1.4
152.16
162.18
pmol/l
0.14
12
80
19
140
1.36
0.58
1.8
1.4
0.91
0.33
nmol/l
0.38
11
104
17
124
1.38
0.55
3.5
3.3
20.25
12.22
index
—
8
73
48
404
1.19
0.54
1.6
1.4
—
—
—
0
0
6
38
1.58
0.54
1.2
1.2
121.00
107.84
%
—
6
31
6
39
1.54
0.53
1.3
1.2
—
—
—
0
0
13
91
1.43
0.53
1.7
1.5
8.37
2.73
ug/l
0.48
13
76
7
47
1.49
0.47
1.0
1.1
—
—
—
0
0
60
526
1.15
0.44
2.8
2.0
—
—
—
0
0
36
303
1.19
0.43
1.5
1.6
944.86
1015.95
mu/l
0.18
29
256
5
31
1.61
0.43
1.0
1.3
—
—
—
0
0
55
481
1.15
0.42
2.3
1.9
—
—
—
0
0
20
158
1.27
0.42
1.5
1.4
6.00
6.36
mmol/l
0.21
20
148
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.8
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
35
297
1.18
0.39
1.3
1.5
—
—
—
0
0
5
36
1.39
0.38
1.0
1.8
77.40
100.08
nmol/24h
—
5
36
10
136
0.73
0.37
1.0
1.0
—
0.41
—
0
49
21
173
1.22
0.33
2.2
1.7
—
—
—
0
0
151
1423
1.07
0.31
1.8
1.8
1.53
1.50
%
0.22
119
1237
34
298
1.14
0.28
4.1
3.7
214.14
1319.06
u/ml
0.69
29
280
31
270
1.15
0.28
1.5
1.5
204.21
267.90
pmol/l
0.24
31
264
46
413
1.12
0.27
1.7
1.8
5.65
5.13
mg/l
0.06
33
315
86
801
1.08
0.25
1.7
1.8
3.12
3.50
mmol/l
2.66
54
580
6
84
0.71
0.24
2.8
1.5
—
—
—
0
0
6
85
0.70
0.24
1.7
2.0
21.50
19.77
nmol/l
—
6
76
18
152
1.19
0.23
13.8
4.9
7.23
7.33
mmol/l
0.05
18
127
33
369
0.89
0.23
1.2
1.4
—
—
—
0
0
5
39
1.28
0.23
1.0
2.0
—
415.78
pmol/l
—
0
5
5
41
1.22
0.22
4.2
2.7
28.20
16.95
ug/l
—
5
34
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
6.15
—
0
12
24
211
1.14
0.20
1.1
1.1
0.17
1.94
u/ml
2.65
12
119
6
52
1.15
0.19
1.3
1.2
—
70.00
%
—
0
8
31
284
1.09
0.15
3.0
2.6
16.33
15.85
%
0.42
31
277
17
150
1.13
0.14
2.0
2.5
38.11
23.16
mg/l
—
9
57
29
266
1.09
0.14
2.0
1.5
—
—
—
0
0
41
383
1.07
0.13
1.1
1.1
1.48
1.53
g/l
0.51
41
383
33
356
0.93
0.13
1.1
1.1
0.58
0.68
ratio
—
10
52
171
1664
1.03
0.12
1.4
1.4
—
—
—
0
0
16
143
1.12
0.11
1.6
1.7
—
—
—
0
0
15
134
1.12
0.11
2.3
2.7
—
—
—
0
0
15
134
1.12
0.11
1.2
1.3
19901.22
105063.37
e6/l
—
9
89
36
338
1.07
0.11
3.3
3.5
0.69
0.79
nmol/l
1.38
29
283
14
125
1.12
0.10
1.5
1.6
3.36
3.97
mg/l
0.32
14
120
20
217
0.92
0.09
2.5
1.9
1.70
1.62
mmol/l
0.17
20
210
6
56
1.07
0.08
7.3
1.8
—
—
—
0
0
6
56
1.07
0.08
7.3
1.8
—
—
—
0
0
6
57
1.05
0.08
7.5
1.8
—
—
—
0
0
5
61
0.82
0.08
7.0
8.4
4.06
294.92
ug/l
—
5
42
8
78
1.03
0.07
1.3
1.4
—
78.18
—
0
11
7
81
0.86
0.07
1.3
1.5
144.71
82.54
umol/l
—
7
81
7
82
0.85
0.07
2.6
1.5
—
—
—
0
0
8
94
0.85
0.06
2.4
1.5
—
—
—
0
0
16
172
0.93
0.06
2.4
1.5
—
—
—
0
0
18
191
0.94
0.04
2.9
1.6
—
—
—
0
0
91
926
0.98
0.04
2.6
2.0
—
—
—
0
0
16
170
0.94
0.04
1.0
1.1
0.45
2.15
u/ml
—
8
85
16
170
0.94
0.04
2.3
1.5
—
—
—
0
0
26
250
1.04
0.03
3.8
1.8
—
—
—
0
0
30
310
0.97
0.03
1.2
1.2
—
—
—
0
0
18
172
1.05
0.02
2.3
1.5
—
—
—
0
0
101
1020
0.99
0.02
2.8
2.1
—
—
—
0
0
12
114
1.05
0.00
1.4
1.4
—
—
—
0
0
16
166
0.96
0.00
2.4
1.5
—
—
—
0
0
14
142
0.99
0.00
1.5
1.3
115.93
386.68
u/l
3.12
14
136
22
218
1.01
0.00
2.3
1.5
—
—
—
0
0
16
163
0.98
0.00
1.1
1.0
—
—
—
0
0
21
207
1.01
0.00
1.3
1.5
—
—
—
0
0
27
273
0.99
0.00
3.4
3.8
35.47
27.89
mg/l
0.40
19
196
16
165
0.97
0.00
2.4
1.5
—
—
—
0
0
16
165
0.97
0.00
2.4
1.5
—
—
—
0
0
11
105
1.05
0.00
1.4
1.5
56.18
48.42
ug/l
0.31
11
105
10
95
1.05
0.00
1.8
1.4
—
—
—
0
0
10
95
1.05
0.00
1.7
1.4
—
—
—
0
0
7
76
0.92
-0.00
2.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
96
0.94
-0.00
1.4
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.9
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.9
1.4
—
—
—
0
0
13
130
1.00
-0.00
2.3
1.8
—
—
—
0
0
5
50
1.00
-0.00
1.8
1.2
12.60
10.52
mm/h
—
5
50
6
64
0.94
-0.00
1.2
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
3.29
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINANAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 0.998 [0.87, 1.15] | 0.977 |
| Birth year | 0.996 [0.99, 1.0] | 0.289 |
During the follow-up period (1.1.1998 — 31.12.2019), 685 out of 3642 females with H7_RETINANAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINANAS | 1.067 [0.91, 1.25] | 0.416 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 601 out of 3031 males with H7_RETINANAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINANAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.25% |
| 5 | 0.647% | 1.275% |
| 10 | 1.654% | 3.094% |
| 15 | 3.085% | 6.093% |
| 20 | 5.306% | 10.422% |
Relationships between endpoints
↥Index endpoint: H7_RETINANAS – Other specified and unspecified retinal disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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