Melanocytic naevi of eyelid, including canthus

CD2_BENIGN_MELANOCYTIC_EYELID

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.1&
  • Hospital discharge: ICD-9 2161A
  • Cause of death: ICD-10 D22.1&
  • Cause of death: ICD-9 2161A

2 out of 7 registries used, show all original rules.

372

4. Check minimum number of events

None

372

5. Include endpoints

None

372

6. Filter based on genotype QC (FinnGen only)

342

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus palpebrae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2724 1781 930
Only index persons 2569 1697 872
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 53.01 52.48 53.88
Only index persons 52.34 51.73 53.51

-FinnGen-

Key figures

All Female Male
Number of individuals 342 231 111
Unadjusted period prevalence (%) 0.07 0.08 0.05
Median age at first event (years) 53.86 50.47 60.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
353
Matched controls
3530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
11858.2
307.7
338
5
CBB30
NOMESCO Finland
Excision of lesion of eyelid
38.1
168.3
111
42
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.9
50.8
93
173
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
9.3
34.6
44
53
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
105.7
18.8
20
*
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
7.3
15.9
24
35
2161A
ICD-9 Finland
Benign neoplasm of skin, Eyelid, including canthus[SILMÄLUOMEN BEN KASVAIN, NAEVUS PIGMENTOSUS]
+∞
15.7
15
*
CBA10
NOMESCO Finland
Biopsy of eyelid
14.3
11.6
19
14
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
3.6
10.7
37
111
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.3
9.6
38
125
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.4
9.0
33
103
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
8.9
49
194
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.7
6.4
34
132
L82
ICD-10 Finland
Seborrhoeic keratosis
2.0
6.4
82
467

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
211
1676
1.64
4.87
5.6
6.1
2.10
1.93
e9/l
0.44
197
1492
173
1310
1.63
4.83
2.4
2.2
—
—
—
0
0
203
1648
1.55
3.88
5.6
6.0
0.57
0.57
e9/l
0.14
184
1422
209
1710
1.54
3.84
5.8
6.3
0.20
0.19
e9/l
0.42
191
1498
203
1656
1.53
3.74
5.6
6.0
0.04
0.04
e9/l
0.82
184
1426
14
40
3.60
3.65
1.2
1.0
2.45
2.17
u/ml
—
9
19
136
1023
1.54
3.63
3.2
2.6
58.62
66.12
u/l
0.55
129
958
18
69
2.70
3.53
1.2
1.5
17972.77
22311.98
e6/l
0.13
13
50
189
1538
1.49
3.40
5.8
6.1
29.15
27.72
%
1.02
178
1468
13
38
3.51
3.35
1.2
1.1
14.27
2.58
u/ml
—
7
16
15
56
2.75
3.10
1.2
1.1
0.92
1.11
u/ml
—
7
33
13
45
2.96
3.06
1.2
1.0
4.55
1.01
u/ml
—
6
24
183
1509
1.44
2.91
5.9
6.0
2.83
2.80
%
0.08
171
1418
183
1515
1.43
2.81
6.0
6.1
8.81
8.70
%
0.21
172
1427
182
1509
1.43
2.75
6.0
6.1
0.65
0.69
%
0.47
171
1412
182
1523
1.40
2.54
5.8
6.0
56.86
57.77
%
0.46
174
1456
268
2405
1.47
2.50
8.4
8.3
76.73
78.10
u/l
0.22
257
2278
134
1069
1.41
2.45
6.0
5.8
—
—
—
0
0
310
2882
1.62
2.32
6.1
5.7
1.86
1.88
mu/l
0.11
294
2674
212
1839
1.38
2.29
9.5
9.8
3.93
4.07
e9/l
0.45
190
1600
42
266
1.66
2.28
1.3
1.2
—
—
—
0
0
5
149
0.33
2.20
2.4
3.4
25.44
24.88
mmol/l
—
5
144
136
1106
1.37
2.16
3.5
3.3
2.37
2.36
mmol/l
0.51
123
1020
122
975
1.38
2.16
7.3
6.3
—
—
—
0
0
12
49
2.50
2.12
1.2
1.0
0.26
1.05
u/ml
—
5
20
270
2466
1.40
1.96
5.1
4.6
14.73
14.73
pmol/l
0.01
252
2265
39
253
1.61
1.94
1.4
1.4
—
—
—
0
0
322
3047
1.65
1.92
5.5
5.1
4.61
4.68
mmol/l
0.61
304
2851
102
806
1.37
1.91
2.3
2.8
332.22
335.66
umol/l
0.13
89
707
97
764
1.37
1.84
4.1
3.9
1.02
1.02
kg/l
1.15
62
513
171
1469
1.32
1.81
2.3
2.5
74.86
76.93
nmol/l
0.44
157
1324
179
1548
1.32
1.80
3.2
3.1
148.48
104.94
ug/l
0.33
170
1445
325
3091
1.65
1.78
6.2
5.9
2.75
2.73
mmol/l
0.11
305
2886
196
1727
1.30
1.68
6.2
6.4
10.16
11.00
umol/l
0.73
187
1647
320
3041
1.56
1.65
5.3
5.0
1.43
1.50
mmol/l
2.60
302
2829
5
15
3.37
1.53
1.8
1.7
—
—
—
0
0
20
116
1.77
1.52
2.8
1.7
312.20
303.18
mu/l
0.06
20
107
321
3063
1.53
1.50
16.1
15.3
25.33
22.67
mg/l
0.57
275
2511
10
45
2.26
1.47
1.1
1.4
—
—
—
0
0
11
52
2.15
1.46
1.2
1.0
4.86
2.63
u/ml
—
6
30
13
66
2.01
1.45
4.5
4.2
19.22
27.56
mg/l
0.50
13
47
5
16
3.15
1.44
1.2
1.1
—
—
—
0
0
56
420
1.40
1.43
1.3
1.3
—
—
—
0
0
278
2596
1.33
1.41
22.9
20.1
332.04
331.76
g/l
0.22
278
2587
9
40
2.28
1.41
20.6
7.7
7.21
7.19
mmol/l
—
9
34
172
1514
1.27
1.40
2.7
2.8
—
—
estimate
—
0
0
157
1367
1.27
1.40
3.5
3.5
6.19
6.20
ph
0.03
82
785
44
321
1.42
1.32
1.4
1.5
—
—
—
0
0
6
24
2.53
1.31
1.2
1.3
—
—
—
0
0
177
1573
1.25
1.29
6.4
7.2
1.22
1.21
mmol/l
0.06
154
1370
79
637
1.31
1.27
3.4
2.7
2.44
2.45
mmol/l
0.58
70
574
97
804
1.28
1.27
2.1
2.1
2.21
2.84
mg/l
3.57
90
694
203
1835
1.25
1.27
5.4
5.1
6.40
6.57
mmol/l
0.78
189
1718
23
147
1.60
1.26
1.2
1.2
—
—
—
0
0
305
2901
1.38
1.26
4.5
4.3
1.28
1.26
mmol/l
0.27
284
2682
160
1414
1.24
1.21
14.8
12.3
1.33
1.20
inr
1.74
131
1178
36
260
1.43
1.15
2.1
2.6
76.30
72.41
e9/l
0.15
25
184
13
73
1.81
1.12
2.5
1.8
119.25
126.25
g/l
—
8
51
77
630
1.28
1.11
1.5
1.3
10.15
9.60
u/ml
0.02
27
246
189
1714
1.22
1.08
3.9
3.9
0.00
4.55
estimate
0.50
34
357
158
1414
1.21
1.01
5.8
6.4
1.22
1.22
mmol/l
0.19
147
1305
81
676
1.26
1.00
1.5
1.3
24.23
35.63
iu/ml
0.70
35
219
9
49
1.86
0.99
1.1
1.4
—
—
—
0
0
331
3214
1.48
0.99
13.5
12.1
25.40
25.09
u/l
0.08
320
3126
310
2979
1.33
0.99
5.1
5.0
5.93
5.88
mmol/l
0.25
295
2755
5
23
2.19
0.98
1.0
1.2
122.80
102.35
pmol/l
—
5
23
51
403
1.31
0.96
1.3
1.4
—
—
—
0
0
7
37
1.91
0.94
1.6
1.2
—
—
—
0
0
186
1700
1.20
0.93
3.9
3.8
0.00
0.00
estimate
-0.00
33
348
80
941
0.81
0.93
1.5
1.4
—
—
—
0
0
154
1384
1.20
0.93
2.1
2.1
98.78
97.41
pmol/l
0.09
66
714
189
1734
1.19
0.90
3.9
3.9
0.00
0.92
estimate
0.51
32
335
90
770
1.23
0.89
3.6
3.8
—
0.29
—
0
7
6
30
2.02
0.87
1.7
1.1
—
—
—
0
0
227
2122
1.20
0.86
3.3
3.3
40.07
43.90
u/l
0.35
217
2006
60
493
1.26
0.85
1.5
1.4
1098.18
542.52
titre
0.54
11
103
232
2174
1.20
0.85
4.8
4.6
—
3.26
—
0
6
6
31
1.95
0.84
3.0
3.9
—
—
—
0
0
92
794
1.21
0.84
1.4
1.3
2.36
1.88
u/ml
0.10
25
230
324
3147
1.36
0.83
14.4
13.6
—
—
—
0
0
6
32
1.89
0.82
1.0
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.2
—
—
—
0
0
6
32
1.89
0.82
2.5
2.0
10.78
10.53
%
—
6
32
222
2076
1.19
0.82
5.1
4.6
1599.00
219.14
e6/l
0.65
12
37
36
280
1.32
0.78
1.4
1.5
—
—
—
0
0
338
3312
1.48
0.74
25.7
23.6
4.48
4.47
e12/l
0.07
332
3252
338
3312
1.48
0.74
25.8
23.6
6.80
6.70
e9/l
0.27
332
3251
7
38
1.86
0.74
1.1
1.1
—
—
—
0
0
53
438
1.25
0.73
2.2
2.5
126.42
107.68
ug/g
0.31
40
356
24
177
1.38
0.73
1.1
1.1
—
—
—
0
0
55
457
1.24
0.72
1.2
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
35.60
31.43
mg/l
—
5
22
5
28
1.80
0.66
1.0
1.3
—
—
—
0
0
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
19
137
1.41
0.66
1.2
1.5
—
12.08
—
0
5
7
44
1.60
0.65
1.9
3.1
—
—
—
0
0
49
408
1.23
0.64
2.6
3.2
6.85
4.86
e9/l
0.34
42
365
11
71
1.57
0.63
2.2
1.6
—
—
—
0
0
51
602
0.82
0.62
2.5
2.8
527.24
528.48
mosm/kgh2o
0.01
45
528
5
30
1.68
0.61
1.0
1.2
—
—
—
0
0
86
760
1.17
0.61
3.5
4.9
—
—
—
0
0
337
3310
1.40
0.61
25.9
23.6
256.33
253.39
e9/l
0.32
332
3263
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
12.3
—
0.63
—
0
21
299
2899
1.21
0.59
6.7
6.3
39.01
38.98
mmol/mol
0.02
279
2743
0
22
0.00
0.59
0.0
1.6
—
69.73
—
0
22
106
955
1.16
0.59
4.4
3.8
0.00
0.01
estimate
0.74
31
322
17
123
1.40
0.59
1.5
1.5
32.70
10.73
u/ml
—
5
23
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
6
36
1.68
0.57
1.2
1.2
—
—
—
0
0
5
89
0.56
0.56
1.2
1.2
12.82
12.14
u/l
—
5
71
6
38
1.59
0.54
3.2
3.1
0.72
0.76
nmol/l
—
6
31
9
61
1.49
0.54
1.4
1.9
—
—
—
0
0
57
492
1.19
0.54
1.5
1.7
1259.26
1186.30
nmol/l
0.23
44
368
106
966
1.14
0.50
2.2
2.2
222.23
159.40
u/l
0.48
98
925
120
1104
1.13
0.49
4.0
3.1
29.54
29.04
u/l
0.06
113
1045
7
109
0.64
0.49
1.1
1.3
—
—
—
0
0
105
958
1.14
0.49
2.8
3.1
—
—
—
0
0
93
844
1.14
0.47
4.0
4.1
—
—
—
0
0
16
120
1.35
0.47
1.3
1.4
102.32
215.42
miu/ml
—
8
59
82
742
1.14
0.43
5.3
5.5
2.62
2.46
ug/l
0.08
74
659
25
304
0.81
0.42
3.0
3.5
6.10
5.71
kpa
1.02
25
295
14
105
1.35
0.41
2.1
2.8
214.67
275.33
mg/l
—
9
39
28
232
1.22
0.41
1.2
1.3
—
—
—
0
0
19
150
1.28
0.41
1.6
4.0
37.05
36.93
°c
0.78
19
150
79
718
1.13
0.39
1.4
1.4
2.44
2.47
g/l
0.04
49
448
39
336
1.18
0.39
4.2
4.1
3.91
20.12
ug/l
0.67
32
270
5
35
1.43
0.39
1.4
1.2
—
—
—
0
0
5
35
1.43
0.39
1.8
1.0
—
—
—
0
0
45
393
1.17
0.39
1.6
1.5
—
—
—
0
0
116
1243
0.90
0.39
3.5
3.2
—
—
—
0
0
70
632
1.13
0.39
1.7
1.8
—
—
—
0
0
143
1347
1.10
0.38
2.0
2.0
1.38
1.33
mmol/l
0.29
126
1136
53
473
1.14
0.35
1.6
2.1
—
—
—
0
0
40
351
1.16
0.33
1.5
1.6
—
—
—
0
0
6
46
1.31
0.33
2.0
2.7
—
—
—
0
0
28
239
1.19
0.32
1.2
1.2
234.92
162.12
u/ml
0.39
19
102
6
47
1.28
0.32
2.0
1.5
—
—
—
0
0
15
119
1.27
0.32
1.2
1.3
—
—
—
0
0
12
92
1.32
0.32
1.0
1.1
—
—
—
0
0
126
1189
1.09
0.32
4.0
3.7
109.50
74.19
e6/l
0.25
88
828
8
106
0.75
0.29
1.0
1.2
—
—
—
0
0
66
606
1.11
0.29
3.9
3.6
198.40
387.55
ng/l
0.59
45
455
105
987
1.09
0.29
3.7
4.1
7.39
7.40
ph
0.46
79
698
18
149
1.22
0.28
1.2
1.2
—
2.79
—
0
10
8
64
1.26
0.27
3.0
2.3
92.70
89.62
%
—
8
64
8
64
1.26
0.27
1.6
1.3
—
—
—
0
0
8
66
1.22
0.27
1.4
1.5
—
—
—
0
0
55
503
1.11
0.26
2.0
2.4
2.39
2.31
g/l
0.46
50
464
9
77
1.17
0.24
2.8
2.3
9.02
7.93
kpa
—
9
77
13
106
1.24
0.23
1.2
1.3
—
—
—
0
0
12
97
1.25
0.23
1.2
1.1
—
83.85
—
0
13
5
39
1.29
0.23
2.8
2.4
—
28.22
—
0
6
111
1058
1.07
0.22
2.3
2.3
—
—
—
0
0
18
154
1.18
0.21
1.8
2.1
0.00
0.00
estimate
—
5
51
0
11
0.00
0.21
0.0
1.5
—
0.00
—
0
11
0
11
0.00
0.21
0.0
2.1
—
5.35
—
0
11
0
10
0.00
0.21
0.0
1.6
—
28.50
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
137
1317
1.07
0.21
3.9
3.7
0.00
0.01
estimate
0.69
29
290
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
0.60
—
0
13
125
1199
1.07
0.20
3.5
3.8
26.35
83.28
ng/l
0.63
73
839
27
302
0.89
0.20
3.0
3.6
7.40
7.39
ph
0.18
12
175
6
48
1.25
0.20
1.0
1.2
—
—
—
0
0
13
108
1.21
0.20
1.2
1.3
—
—
—
0
0
13
108
1.21
0.20
1.2
1.3
—
—
—
0
0
12
99
1.22
0.20
1.2
1.3
—
—
—
0
0
6
50
1.20
0.20
1.0
1.5
37.42
28.43
u/l
—
6
42
147
1419
1.06
0.20
10.4
11.0
0.00
0.00
e9/l
0.67
134
1147
59
551
1.08
0.19
1.6
1.6
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
23
259
0.88
0.19
1.9
2.9
4.26
4.33
kpa
0.07
23
252
13
109
1.20
0.19
1.2
1.3
—
—
—
0
0
97
926
1.07
0.18
1.8
1.7
21.78
21.04
nmol/l
0.18
86
779
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
22
247
0.88
0.18
5.0
3.5
—
—
—
0
0
20
176
1.14
0.18
10.8
7.1
—
—
—
0
0
40
369
1.09
0.17
1.6
1.7
—
—
—
0
0
75
712
1.07
0.17
2.9
2.6
5.14
6.47
e6/l
0.38
68
648
8
69
1.16
0.16
1.3
1.3
—
—
—
0
0
8
73
1.10
0.16
2.1
3.1
58.33
59.60
%
—
8
73
47
501
0.93
0.15
2.7
2.9
4.64
2.87
e6/l
0.38
22
230
13
112
1.17
0.14
1.2
1.2
0.91
0.92
g/l
0.05
13
112
34
315
1.09
0.14
2.4
2.3
30.79
32.37
u/l
0.18
28
259
8
100
0.80
0.13
1.1
2.9
—
—
—
0
0
17
190
0.89
0.13
1.2
1.2
—
—
—
0
0
36
385
0.93
0.12
1.4
1.4
—
—
—
0
0
108
1046
1.05
0.12
3.1
3.1
110.21
107.33
e6/l
0.01
84
785
22
201
1.10
0.11
3.0
2.3
13.94
13.47
nmol/l
0.12
22
188
38
359
1.07
0.10
8.2
8.9
7.43
7.42
ph
0.44
18
211
32
302
1.07
0.09
1.8
1.4
—
—
—
0
0
15
136
1.11
0.08
1.1
1.1
—
—
—
0
0
19
175
1.09
0.08
1.8
1.7
—
—
—
0
0
17
185
0.91
0.08
2.1
2.5
1.21
1.23
%
0.05
17
185
102
1045
0.97
0.08
4.6
4.1
12.96
11.99
mg/mmol
0.08
65
627
5
64
0.78
0.08
3.4
2.7
21.30
8.32
pmol/l
—
5
64
7
65
1.08
0.08
1.6
1.2
—
—
—
0
0
15
164
0.91
0.08
1.1
1.1
—
—
—
0
0
30
317
0.94
0.08
1.6
1.7
—
—
—
0
0
7
67
1.05
0.08
2.0
1.9
4.76
4.92
mmol/24h
—
7
58
12
108
1.12
0.07
1.2
1.1
1.50
1.60
g/l
0.57
12
108
28
265
1.06
0.07
3.9
4.6
0.00
0.12
%
—
8
74
20
214
0.93
0.07
5.6
2.9
25.76
35.61
u/ml
0.43
20
205
91
931
0.97
0.07
2.9
3.1
—
0.13
—
0
16
8
91
0.88
0.07
1.0
1.6
—
—
—
0
0
100
1021
0.97
0.06
4.1
3.4
82.41
62.24
mg/l
0.31
63
644
65
632
1.03
0.06
1.5
1.8
108621102.50
9363736.44
pmol/l
0.44
58
534
25
264
0.94
0.06
5.5
8.3
—
—
—
0
0
17
182
0.93
0.05
2.1
2.5
0.56
0.63
%
0.69
17
182
15
139
1.08
0.05
4.5
2.9
—
—
—
0
0
13
141
0.92
0.05
1.8
1.9
—
—
—
0
0
11
100
1.10
0.05
1.5
1.3
332.00
334.22
ug/g
—
6
57
43
444
0.96
0.05
2.3
3.1
1.01
0.74
ug/l
0.34
26
285
25
262
0.95
0.05
1.6
1.9
3.30
3.47
mmol/l
0.30
20
198
26
271
0.96
0.04
3.7
5.1
0.00
0.01
%
—
6
68
88
891
0.98
0.02
3.1
3.0
0.53
0.56
e6/l
0.03
64
631
97
962
1.01
0.01
3.5
3.2
0.00
0.09
estimate
0.52
29
278
29
283
1.03
0.01
3.8
4.5
0.56
0.82
%
—
9
92
10
94
1.07
0.01
1.6
2.6
14.73
11.42
mg/l
—
10
87
21
216
0.97
0.00
1.5
2.4
—
—
—
0
0
26
266
0.98
0.00
3.8
4.4
0.33
0.49
%
—
6
79
30
294
1.02
0.00
1.8
2.1
0.00
0.00
estimate
—
5
61
36
354
1.02
0.00
8.6
8.9
1.65
1.06
mmol/l
0.52
30
305
108
1074
1.01
0.00
3.8
3.3
6.72
7.61
mmol/l
1.33
95
900
11
108
1.02
0.00
5.5
10.1
—
—
—
0
0
12
118
1.02
0.00
1.1
2.0
11242.12
5018.64
u/l
—
5
44
12
122
0.98
0.00
1.3
2.2
9.35
10.40
g/l
0.69
12
109
10
99
1.01
0.00
3.2
2.3
1.59
1.48
mg/l
—
10
88
15
149
1.01
0.00
2.5
2.4
—
—
—
0
0
37
369
1.00
0.00
1.4
1.5
—
—
—
0
0
19
193
0.98
0.00
4.5
2.9
7.43
7.42
ph
0.59
14
156
29
293
0.99
0.00
1.8
2.3
0.20
0.22
g/l
0.51
29
277
10
105
0.95
0.00
1.2
1.3
—
—
—
0
0
11
105
1.05
0.00
4.5
2.0
25.21
24.74
mmol/l
0.18
11
105
13
135
0.96
0.00
2.5
1.4
0.20
0.30
mg/l
—
6
52
28
275
1.02
0.00
3.8
3.9
7.38
7.36
ph
0.87
21
189
75
754
0.99
0.00
1.6
1.6
1.25
1.26
mg/l
0.01
60
595
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
34.60
—
0
5
8
80
1.00
-0.00
2.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
17
170
1.00
-0.00
1.1
1.1
—
95.17
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
0.02
—
0
8
0
6
0.00
-0.00
0.0
2.5
—
9142.50
—
0
6
5
49
1.02
-0.00
1.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
2.2
3.6
4.20
4.55
e9/l
—
5
51
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
85
0.94
-0.00
1.3
1.3
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
8.03
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
17.76
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
1.21
—
0
7
0
6
0.00
-0.00
0.0
2.7
—
3.00
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.4
2.2
3.40
6.31
umol/l
—
5
39

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_EYELID and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EYELID 1.0 [0.84, 1.19] 0.997
Birth year 0.992 [0.98, 1.0] 0.082

During the follow-up period (1.1.1998 — 31.12.2019), 204 out of 1551 females with CD2_BENIGN_MELANOCYTIC_EYELID died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EYELID 0.878 [0.71, 1.08] 0.225
Birth year 0.99 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 131 out of 811 males with CD2_BENIGN_MELANOCYTIC_EYELID died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_EYELID.

N-year risk Females Males
1 0.089% 0.209%
5 0.526% 0.992%
10 1.281% 2.568%
15 2.448% 5.089%
20 4.458% 8.86%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_EYELID – Melanocytic naevi of eyelid, including canthus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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