Benign neoplasm: Female genital organ, unspecified

CD2_BENIGN_FEMALE_GEN_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.9&
  • Hospital discharge: ICD-9 221[8-9]
  • Hospital discharge: ICD-8 2219
  • Cause of death: ICD-10 D28.9&
  • Cause of death: ICD-9 221[8-9]
  • Cause of death: ICD-8 2219

2 out of 7 registries used, show all original rules.

123

4. Check minimum number of events

None

123

5. Include endpoints

None

123

6. Filter based on genotype QC (FinnGen only)

111

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum organi genitalis feminini non specificati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 995 995 -
Only index persons 837 837 -
Unadjusted period prevalence (%)
Whole population 0.03 0.03 -
Only index persons 0.03 0.03 -
Median age at first event (years)
Whole population - 44.49 -
Only index persons - 42.31 -

-FinnGen-

Key figures

All Female Male
Number of individuals 111 111 -
Unadjusted period prevalence (%) 0.04 0.04 -
Median age at first event (years) 40.14 40.14 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
114
Matched controls
1140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D28.9
ICD-10 Finland
Benign neoplasm: Female genital organ, unspecified
+∞
84.0
70
*
22199
ICD-8 Finland
Benign neoplasm of other female genital organs, Unspecified site
+∞
32.9
30
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
29.0
10.1
13
5
2218X
ICD-9 Finland
Benign neoplasm of other female genital organs, Other specified sites of female genital organs
+∞
9.5
9
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
94
2.66
3.69
5.0
3.7
—
—
—
0
0
7
12
6.13
3.07
1.4
2.6
90.80
89.52
%
—
7
12
34
199
2.01
2.73
2.4
1.8
434.85
488.55
pmol/l
0.61
26
165
8
20
4.22
2.62
1.9
2.4
15.86
15.76
%
—
8
20
47
321
1.79
2.31
4.4
4.2
0.00
0.00
estimate
-0.00
22
116
7
19
3.85
2.19
1.4
3.5
4.77
5.01
kpa
—
7
19
7
19
3.85
2.19
1.4
3.5
8.70
9.32
kpa
—
7
19
23
130
1.96
2.00
1.6
1.2
—
—
—
0
0
17
90
2.04
1.76
2.5
2.7
70.96
76.74
e9/l
0.36
11
62
51
378
1.63
1.76
2.6
3.2
—
—
—
0
0
45
325
1.64
1.71
1.9
1.7
25.47
23.05
nmol/l
0.35
36
267
57
439
1.60
1.66
4.7
4.0
0.00
0.01
estimate
0.50
20
101
23
141
1.79
1.57
3.9
1.9
145.51
113.11
ug/g
0.29
18
111
45
334
1.57
1.50
4.8
3.6
0.00
0.00
estimate
-0.00
20
100
7
29
2.50
1.41
1.0
1.4
809.00
147.63
ug/l
—
7
24
91
802
1.67
1.36
9.7
8.0
72.40
77.42
u/l
1.12
81
740
36
261
1.55
1.31
9.3
4.9
—
—
—
0
0
5
18
2.86
1.30
1.0
1.1
—
—
—
0
0
7
30
2.42
1.14
1.6
3.2
7.43
7.43
ph
—
7
30
12
66
1.91
1.14
3.3
6.1
24.83
25.25
mmol/l
0.16
12
66
15
92
1.73
1.03
4.4
2.7
5.80
6.12
ph
—
10
65
19
126
1.61
0.99
1.8
1.7
—
—
—
0
0
61
514
1.40
0.98
2.2
2.7
—
—
estimate
—
0
0
60
505
1.40
0.97
5.9
6.0
3.16
2.68
%
0.74
50
465
60
506
1.39
0.95
6.1
6.0
0.78
0.67
%
0.60
49
466
82
733
1.42
0.90
5.1
5.1
—
297.00
—
0
14
26
191
1.47
0.87
1.5
1.7
—
—
—
0
0
37
291
1.40
0.87
3.2
3.5
0.53
0.38
e6/l
0.23
27
197
68
591
1.37
0.87
5.0
4.3
0.00
0.00
estimate
-0.00
21
120
64
551
1.37
0.87
6.5
6.0
0.58
0.54
e9/l
0.78
49
465
64
554
1.35
0.82
6.5
6.0
0.04
0.04
e9/l
0.03
49
467
33
259
1.39
0.78
3.6
4.0
—
—
—
0
0
36
287
1.37
0.77
2.3
2.2
3.19
2.80
mg/l
0.28
27
247
61
529
1.33
0.75
3.5
3.2
93.99
77.99
ug/l
0.30
54
494
65
569
1.33
0.75
6.7
6.0
0.20
0.18
e9/l
0.59
51
488
21
153
1.46
0.74
1.2
1.3
—
—
—
0
0
64
562
1.32
0.71
6.5
6.0
1.91
1.83
e9/l
0.35
49
492
56
483
1.31
0.71
16.1
11.2
0.00
0.00
e9/l
0.50
50
386
13
86
1.58
0.69
1.1
1.3
—
—
—
0
0
5
27
1.89
0.69
1.2
1.3
—
—
—
0
0
58
504
1.31
0.69
6.2
6.1
8.90
8.42
%
0.64
47
468
14
95
1.54
0.68
3.8
4.0
7.37
7.36
ph
—
7
62
59
515
1.30
0.67
6.2
6.0
30.27
27.71
%
0.72
50
483
41
342
1.31
0.65
2.5
2.3
55.83
67.36
u/l
0.40
35
310
66
589
1.29
0.62
4.9
4.2
0.00
0.00
estimate
-0.00
22
127
8
54
1.52
0.58
1.3
2.0
—
—
—
0
0
15
108
1.45
0.56
1.3
1.4
—
—
—
0
0
68
614
1.27
0.56
8.8
9.7
3.78
4.03
e9/l
0.52
55
533
52
456
1.26
0.54
10.8
11.4
1.08
1.18
inr
1.06
44
375
65
585
1.26
0.54
4.9
4.2
0.00
0.00
estimate
-0.00
22
121
22
172
1.35
0.53
2.2
2.4
12.72
12.53
umol/l
0.04
17
157
6
40
1.53
0.52
1.0
1.4
364.33
360.40
mu/l
—
6
34
41
351
1.26
0.52
6.6
5.5
—
—
—
0
0
20
157
1.33
0.47
2.1
2.4
2.53
2.40
g/l
0.27
15
143
17
130
1.36
0.47
1.2
1.3
—
—
—
0
0
23
187
1.29
0.43
2.7
1.7
1237.36
1171.75
nmol/l
0.11
14
142
5
33
1.54
0.42
1.8
2.2
26.50
24.96
mmol/l
—
5
33
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
27
226
1.26
0.41
1.2
1.3
1.24
9.38
u/ml
—
8
84
8
61
1.33
0.40
6.3
1.7
—
—
—
0
0
19
152
1.30
0.40
1.5
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
16
127
1.30
0.36
1.3
1.4
—
—
—
0
0
15
118
1.31
0.35
1.5
1.5
—
—
—
0
0
27
231
1.22
0.34
2.7
2.7
2.47
2.46
mmol/l
0.05
27
210
6
46
1.32
0.33
1.5
2.3
27.48
24.73
mmol/l
—
6
46
107
1043
1.42
0.32
15.3
13.3
—
—
—
0
0
28
243
1.20
0.31
1.4
1.3
37.48
30.52
iu/ml
—
6
86
13
103
1.30
0.29
1.6
3.1
7.40
7.39
ph
—
8
54
55
509
1.16
0.28
7.4
5.2
1.22
1.22
mmol/l
0.20
48
465
8
66
1.23
0.27
4.6
7.0
0.80
0.65
%
—
8
66
5
71
0.69
0.27
4.0
1.8
0.70
1.77
g/l
—
5
65
8
67
1.21
0.27
4.6
7.1
92.63
95.36
%
—
8
67
8
67
1.21
0.27
4.6
7.0
1.43
1.19
%
—
8
67
38
343
1.16
0.27
3.3
3.6
25.55
27.43
e6/l
0.06
31
246
38
343
1.16
0.27
1.7
2.2
—
—
—
0
0
28
247
1.18
0.26
2.8
2.8
340.79
317.36
umol/l
0.51
19
218
31
345
0.86
0.25
5.4
6.3
—
—
—
0
0
52
483
1.14
0.24
2.5
2.1
—
—
—
0
0
29
258
1.17
0.24
1.7
1.4
2.05
2.46
g/l
0.77
19
144
24
210
1.18
0.24
1.8
1.9
—
—
—
0
0
10
79
1.29
0.23
2.1
3.1
—
—
—
0
0
99
1014
0.82
0.22
5.9
6.0
2.66
2.75
mmol/l
0.48
91
933
0
11
0.00
0.21
0.0
4.1
—
0.78
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
18
155
1.19
0.21
2.3
2.4
23.38
21.22
%
0.21
13
142
9
112
0.79
0.21
1.1
1.1
—
—
—
0
0
53
497
1.12
0.21
2.4
2.1
99.75
99.96
pmol/l
0.01
30
226
0
13
0.00
0.21
0.0
3.1
—
—
—
0
0
11
90
1.25
0.20
1.5
1.7
—
—
—
0
0
12
100
1.22
0.19
1.3
3.0
3.04
2.25
mmol/l
0.43
12
84
29
318
0.88
0.18
1.9
1.6
—
—
—
0
0
16
138
1.19
0.18
3.3
5.6
101.69
104.22
mmol/l
0.90
16
138
11
91
1.23
0.18
3.7
6.4
—
—
—
0
0
7
60
1.18
0.18
1.4
1.2
—
—
—
0
0
45
479
0.90
0.17
1.9
1.9
1.34
1.35
mmol/l
0.02
32
395
10
119
0.82
0.16
10.4
5.9
2.76
1.06
mmol/l
—
10
107
44
467
0.91
0.16
3.3
3.8
6.31
6.27
ph
0.10
27
256
103
1011
1.19
0.15
16.3
15.6
18.88
21.06
mg/l
0.27
87
813
23
251
0.90
0.13
3.7
4.3
1.02
1.02
kg/l
0.41
15
165
28
301
0.91
0.12
1.5
1.3
0.47
2.00
u/ml
—
6
73
58
558
1.08
0.11
7.4
5.9
1.22
1.22
mmol/l
0.04
42
471
41
390
1.08
0.11
3.5
3.1
—
—
—
0
0
13
116
1.14
0.10
3.9
5.1
4.20
12.69
ug/l
—
8
92
13
116
1.14
0.10
1.7
1.5
—
—
—
0
0
6
53
1.14
0.09
2.3
2.3
—
—
—
0
0
6
58
1.04
0.08
1.7
1.7
—
—
—
0
0
99
1001
0.92
0.06
5.1
5.2
4.69
4.76
mmol/l
0.28
91
926
42
408
1.05
0.04
3.6
4.5
79.48
59.87
e6/l
0.18
31
260
14
148
0.94
0.02
1.7
2.0
—
—
—
0
0
96
952
1.05
0.02
6.6
6.4
37.37
39.01
mmol/mol
1.51
89
887
99
983
1.05
0.01
7.2
6.2
1.56
1.88
mu/l
2.59
93
913
40
393
1.03
0.01
5.1
3.9
15.04
36.46
ng/l
1.36
23
270
36
359
1.00
0.00
5.7
3.6
7.40
7.40
ph
0.35
27
254
27
267
1.01
0.00
1.7
1.7
0.72
1.25
mg/l
1.14
20
220
34
337
1.01
0.00
3.0
3.1
57.94
27.62
mg/l
0.30
19
201
35
353
0.99
0.00
3.0
3.0
6.99
7.08
mmol/l
0.04
26
284
35
345
1.02
0.00
4.0
3.7
5.87
6.22
mg/mmol
0.02
19
191
99
995
0.96
0.00
5.1
5.0
1.61
1.58
mmol/l
0.36
91
912
98
985
0.96
0.00
5.6
5.2
5.73
5.82
mmol/l
0.43
92
907
94
936
1.02
0.00
4.2
4.2
1.20
1.21
mmol/l
0.08
84
845
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
38.42
—
0
5
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
6
59
1.02
0.00
2.2
3.1
7.45
7.43
ph
—
6
48
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
72
0.97
0.00
1.6
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
52.40
—
0
5
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
32.43
—
0
7
0
6
0.00
-0.00
0.0
2.5
—
1.00
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
33.81
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
0.37
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
94.98
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
60
1.00
-0.00
1.3
2.4
1.03
1.19
%
—
6
60
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
6.53
—
0
9
6
60
1.00
-0.00
1.3
2.4
0.65
0.61
%
—
6
60
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.3
1.3
29.78
21.63
iu/l
—
6
56
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_FEMALE_GEN_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FEMALE_GEN_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_FEMALE_GEN_NOS – Benign neoplasm: Female genital organ, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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