Other and unspecified acute skin changes due to ultraviolet radiation

L12_OTHACUSKINSUNNAS

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L56.8, L56.9
  • Hospital discharge: ICD-9 6927
  • Hospital discharge: ICD-8 6928
  • Hospital discharge: excluded ICD-9 6927F
  • Cause of death: ICD-10 L56.8, L56.9
  • Cause of death: ICD-9 6927
  • Cause of death: ICD-8 6928
  • Cause of death: excluded ICD-9 6927F

2 out of 7 registries used, show all original rules.

1040

4. Check minimum number of events

None

1040

5. Include endpoints

None

1040

6. Filter based on genotype QC (FinnGen only)

949

Control definitions (FinnGen only)

Control exclude
L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9789 4557 5076
Only index persons 6433 3241 3192
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.14
Only index persons 0.12 0.12 0.12
Median age at first event (years)
Whole population 44.43 47.31 41.57
Only index persons 35.57 39.46 31.63

-FinnGen-

Key figures

All Female Male
Number of individuals 949 425 524
Unadjusted period prevalence (%) 0.20 0.15 0.24
Median age at first event (years) 38.86 39.33 38.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
973
Matched controls
9730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
307.7
486
*
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
+∞
255.8
234
*
L57.0
ICD-10 Finland
Actinic keratosis
10.8
168.3
202
230
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.1
125.5
217
376
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
26.2
119.4
84
35
TQW99
NOMESCO Finland
Other minor procedure on skin
9.5
109.6
140
170
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
28.7
106.1
72
27
ZXC20
NOMESCO Finland
Use of chemical agents
15.9
97.5
86
59
69288
ICD-8 Finland
Other eczema and dermatitis, E causis alii definitis
+∞
93.2
88
*
L56.9
ICD-10 Finland
Acute skin change due to ultraviolet radiation, unspecified
247.6
89.1
90
*
D07AB08
ATC
desonide; topical
4.6
73.4
205
534
69283
ICD-8 Finland
Other eczema and dermatitis, Dysidroticum (pompholyx)
+∞
57.9
55
*
E0000UV, ,
ATC
2.8
54.3
499
2654
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
16.8
49.8
42
26
E000001, ,
ATC
3.1
48.5
268
1076
D07AC01
ATC
betamethasone; topical
2.6
47.3
457
2447
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
13.0
47.2
46
37
ZXC50
NOMESCO Finland
Cryotherapy
14.5
47.0
43
31
D07AB02
ATC
hydrocortisone butyrate; topical
2.7
45.6
374
1840
EAA10
NOMESCO Finland
Excision of lesion of lip
12.4
43.9
44
37
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.9
43.8
257
1060
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.7
41.1
146
443
ZXC10
NOMESCO Finland
Use of laser
7.2
39.8
61
90
D07AC13
ATC
mometasone; topical
2.5
37.7
353
1819
69280
ICD-8 Finland
Other eczema and dermatitis, E radiatione solari
+∞
36.7
35
*
E000002, ,
ATC
3.4
34.8
143
475
R06AE07
ATC
cetirizine; oral
2.2
31.8
441
2645
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
10.6
29.9
33
32
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
11.4
29.5
31
28
L20.0
ICD-10 Finland
Besnier prurigo
4.1
29.0
83
215
L57.8
ICD-10 Finland
Other skin changes due to chronic exposure to nonionizing radiation
154.6
28.8
30
*
L30.3
ICD-10 Finland
Infective dermatitis
4.8
27.4
64
141
D07AA02
ATC
hydrocortisone; topical
2.7
26.8
166
690
N05BB01
ATC
hydroxyzine; systemic
3.5
25.5
93
285
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.1
24.5
109
377
69200
ICD-8 Finland
Other eczema and dermatitis, Due to detergents
+∞
24.1
23
*
D07AD01
ATC
clobetasol; topical
2.4
23.9
195
920
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
34.3
23.4
30
9
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
46.2
22.4
27
6
H02AB06
ATC
prednisolone; systemic
1.9
20.5
506
3552
D07BC01
ATC
betamethasone and antiseptics; topical
2.5
20.5
147
652
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.4
20.1
149
671
D07XC01
ATC
betamethasone; topical
2.4
19.6
151
691
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
6.9
18.8
29
43
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
193.6
18.6
19
*
XQ802
NOMESCO Finland
Epicutan test
4.1
18.4
52
133
E000003, ,
ATC
3.6
18.1
61
177
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
53.6
18.0
21
*
E000007, ,
ATC
3.5
17.6
63
190
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
4.1
16.9
47
119
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
20.5
16.5
24
12
H02AB07
ATC
prednisone; oral
2.1
16.2
165
845
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
61.1
15.8
18
*
E000006, ,
ATC
2.8
15.6
84
322
D02AX
ATC
Other emollients and protectives
4.2
15.3
41
101
EAA30
NOMESCO Finland
Partial excision of lower lip
32.3
14.8
19
6
XQ800
NOMESCO Finland
Prick test
2.8
14.7
74
274
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.2
14.6
58
187
TQW80
NOMESCO Finland
Local dermatologic skincare
4.5
14.6
36
83
L56.4
ICD-10 Finland
Polymorphous light eruption
22.7
14.3
20
9
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.3
13.9
54
172
D11AH01
ATC
tacrolimus; topical
17.9
13.9
21
12
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
17.9
13.9
21
12
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.4
13.8
101
450
ZQZ00
NOMESCO Finland
Treatment of several skin areas
26.2
13.4
18
7
J01FF01
ATC
clindamycin; systemic
1.8
12.9
269
1738
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.8
12.9
29
62
D07CC01
ATC
betamethasone and antibiotics; topical
2.1
12.9
134
689
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
50.7
12.9
15
*
XQ848
NOMESCO Finland
Dermatological photography
4.1
12.5
34
85
L30.0
ICD-10 Finland
Nummular dermatitis
3.1
12.4
51
168
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
11.9
69
275
S29
ICPC
Skin symptom/complaint other
1.8
11.7
196
1182
D06BB10
ATC
imiquimod; topical
3.2
11.7
47
153
D05BB02
ATC
acitretin; oral
3.8
11.5
35
95
69230
ICD-8 Finland
Other eczema and dermatitis, Due to drugs
121.4
11.4
12
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.5
11.4
74
311
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
11.3
227
1446
ZZR00
NOMESCO Finland
Flap of skin
3.9
11.0
32
84
11006
ICD-8 Finland
Dermatophytosis, Pedis
43.8
10.9
13
*
R03AC03
ATC
terbutaline; inhalant
2.0
10.7
134
735
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
21.7
10.7
15
7
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
10.4
160
940
J01DB01
ATC
cefalexin; oral
1.7
10.3
751
6497
J01AA04
ATC
lymecycline; systemic
2.0
10.1
110
574
S76
ICPC
Skin infection other
2.5
9.9
63
263
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
26.3
9.8
13
5
L01BC02
ATC
fluorouracil; systemic, topical
20.3
9.8
14
7
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
3.1
9.8
41
137
A46
ICD-10 Finland
Erysipelas
1.8
9.7
166
1006
R03AK08
ATC
formoterol and beclometasone; inhalant
2.8
9.6
48
177
L04AX01
ATC
azathioprine; systemic
3.0
9.5
42
145
D07XB05
ATC
dexamethasone; topical
3.3
9.4
35
109
R06AX27
ATC
desloratadine; oral
1.7
9.4
215
1411
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
9.3
200
1290
ZXC15
NOMESCO Finland
Use of photodynamic technique
10.8
9.3
17
16
Z2221
NOMESCO Finland
Medical doctor
1.6
9.1
248
1698
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
4.8
9.1
20
42
Z71.8
ICD-10 Finland
Other specified counselling
1.6
9.1
286
2029
R03BB04
ATC
tiotropium bromide; inhalant
1.9
9.0
129
740
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.9
185
1180
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.7
8.9
183
1164
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
24.3
8.9
12
5
Z3231
NOMESCO Finland
Registered nurse
1.6
8.9
261
1818
D05AX02
ATC
calcipotriol; topical
2.8
8.7
44
164
J01AA07
ATC
tetracycline; systemic
1.9
8.6
121
689
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
8.6
76
367
D06BX01
ATC
metronidazole; topical
2.0
8.5
97
514
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.5
308
2247
D09AB01
ATC
zinc bandage without supplements; topical
3.7
8.5
26
71
S21
ICPC
Skin texture symptom/complaint
1.8
8.5
138
822
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
10.9
8.3
15
14
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
14.6
8.2
13
9
D06AX01
ATC
fusidic acid; topical
2.0
8.1
89
467
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
22.2
8.0
11
5
R06AX13
ATC
loratadine; oral
1.8
8.0
119
690
L71.8
ICD-10 Finland
Other rosacea
4.5
7.9
19
43
Z01.2
ICD-10 Finland
Dental examination
1.5
7.9
362
2768
K13.09
ICD-10 Finland
Disease of the lips UNS
45.3
7.7
9
*
69009
ICD-8 Finland
Seborrhoeic dermatitis, Unspecified
25.2
7.6
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
7.5
289
2126
J46
ICD-10 Finland
Status asthmaticus
3.1
7.5
31
103
T78.4
ICD-10 Finland
Allergy, unspecified
2.8
7.5
37
136
S18
ICPC
Laceration/cut
1.5
7.4
427
3404
R06AE09
ATC
levocetirizine; oral
1.8
7.4
110
638
R03DC03
ATC
montelukast; oral
1.7
7.3
134
824
6929A
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA NUMMULARE]
+∞
7.3
7
*
6927X
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[DERMATITIS PHOTOTOXICA NUD]
+∞
7.3
7
*
P01BA02
ATC
hydroxychloroquine; oral
2.0
7.2
75
385
N02AX02
ATC
tramadol; systemic, rectal
1.4
7.2
415
3303
N06AX11
ATC
mirtazapine; oral
1.5
7.2
304
2279
70908
ICD-8 Finland
Other diseases of skin, Alii definiti
30.2
7.2
9
*
D05AX52
ATC
calcipotriol, combinations; topical
2.3
7.2
51
225
D07AC14
ATC
methylprednisolone aceponate; topical
2.4
7.1
50
219
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.0
167
1100
S01GX04
ATC
nedocromil; ophthalmic
4.2
7.0
18
43
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.4
7.0
47
202
D07AB01
ATC
clobetasone; topical
2.7
7.0
36
136
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.6
6.9
38
148
J01MA12
ATC
levofloxacin; systemic
1.6
6.9
188
1281
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
6.8
47
204
R03BA02
ATC
budesonide; inhalant
1.6
6.8
160
1050
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.8
146
937
L26
ICD-10 Finland
Exfoliative dermatitis
16.8
6.8
10
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
6.7
462
3780
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.7
252
1840
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
6.7
173
1164
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
3.1
6.5
27
90
R03AC02
ATC
salbutamol; inhalant
1.4
6.5
474
3913
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
5.7
6.5
17
30
6924B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS ALLERGICA]
70.3
6.4
7
*
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
70.3
6.4
7
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
6.4
164
1100
L04AB04
ATC
adalimumab; parenteral
3.8
6.4
19
51
R06AX22
ATC
ebastine; oral
1.7
6.4
135
863
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
5.2
6.3
18
35
6927A
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERYTHEMA SOLARE]
+∞
6.3
6
*
C44.00
ICD-10 Finland
Malignant tumor of the lip skin without histology
+∞
6.3
6
*
Y1203, ,
ICD-8 Finland
+∞
6.3
6
*
6927F
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERUPTIO POLYMORPHICA SOLARIS]
+∞
6.3
6
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.2
329
2561
J01FA01
ATC
erythromycin; systemic
1.8
6.2
99
586
J01DA01
ATC
[U] cefalexin
1.4
6.1
558
4764
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.1
267
2004
J01FA06
ATC
roxithromycin; oral
1.4
6.1
353
2789
Y1202
ICD-8 Finland
Skin tests, Allergy tests
12.6
6.1
10
8
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.0
6.1
62
317
UJF32
NOMESCO Finland
Coloscopy
1.5
6.1
250
1855
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
10.1
6.0
11
11
L43.8
ICD-10 Finland
Other lichen planus
3.5
6.0
20
58

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
94
326
3.08
21.01
1.3
1.2
—
—
—
0
0
534
4189
1.61
11.75
8.1
6.2
0.22
0.20
e9/l
0.96
478
3611
399
2922
1.62
11.66
3.1
2.1
—
—
—
0
0
517
4054
1.59
11.17
7.7
6.1
0.62
0.61
e9/l
0.29
457
3437
518
4069
1.58
11.07
7.7
6.1
0.04
0.04
e9/l
0.28
457
3453
171
1011
1.84
10.87
1.4
1.3
429.27
506.83
titre
0.48
41
246
520
4119
1.56
10.49
7.7
6.2
1.87
1.92
e9/l
0.22
468
3585
565
4562
1.57
10.45
12.1
9.6
4.13
4.23
e9/l
0.48
508
3952
224
1494
1.65
9.15
2.9
3.3
0.83
0.82
mmol/l
0.87
209
1406
145
860
1.81
9.04
2.9
2.2
181.67
138.55
ug/g
0.94
116
690
136
795
1.83
8.89
2.6
2.4
40.32
33.49
u/l
0.59
112
658
367
2780
1.51
8.53
7.9
5.9
—
—
—
0
0
319
2355
1.53
8.33
2.8
2.3
2.85
2.99
mg/l
0.42
273
1998
450
3573
1.48
8.22
3.8
3.0
164.07
147.14
ug/l
0.60
418
3276
469
3755
1.48
8.21
8.0
6.2
57.85
58.01
%
0.10
453
3575
470
3766
1.48
8.19
8.0
6.2
3.06
2.88
%
0.65
448
3518
469
3767
1.47
8.01
8.2
6.3
9.24
9.11
%
0.43
446
3524
468
3766
1.47
7.87
8.2
6.3
0.65
0.67
%
0.31
447
3514
474
3824
1.47
7.86
8.0
6.3
26.36
26.49
%
0.09
455
3612
490
3997
1.46
7.57
7.9
6.6
1.20
1.21
mmol/l
1.20
462
3678
299
2224
1.50
7.36
3.1
2.8
358.17
354.20
umol/l
0.24
259
1925
341
2620
1.46
7.08
5.3
4.5
—
—
—
0
0
203
1414
1.55
6.73
3.4
2.5
2.29
2.27
g/l
0.13
195
1308
277
2062
1.48
6.69
2.9
2.5
—
—
—
0
0
84
461
1.90
6.68
1.5
1.2
838.00
214.60
u/ml
1.41
77
425
61
301
2.10
6.54
2.1
1.9
18.32
9.93
iu/ml
0.27
18
76
526
4433
1.41
6.32
8.2
7.3
1.21
1.21
mmol/l
0.66
473
3810
189
1314
1.54
6.28
3.6
2.5
20.44
22.16
%
1.04
182
1224
703
6243
1.45
6.25
11.2
8.5
82.17
81.55
u/l
0.13
679
5909
343
2687
1.43
6.25
5.7
4.1
7.40
7.40
ph
0.33
242
1951
151
1011
1.58
5.91
1.6
1.3
—
—
—
0
0
65
344
1.95
5.78
1.2
1.4
—
15.20
—
0
7
114
718
1.67
5.70
1.8
1.6
—
—
—
0
0
203
1466
1.49
5.60
1.4
1.5
2.87
2.67
g/l
0.49
109
865
62
328
1.95
5.53
3.0
3.7
44.56
48.03
mg/l
0.10
54
284
62
328
1.95
5.53
3.0
3.7
41.16
70.32
mg/l
0.90
54
283
526
4492
1.37
5.52
8.0
6.9
11.35
11.92
umol/l
0.39
504
4293
137
921
1.57
5.25
1.7
1.6
—
—
—
0
0
207
1520
1.46
5.22
3.5
2.6
11.81
12.44
umol/l
0.66
199
1415
211
1556
1.45
5.20
3.5
3.1
0.74
1.13
e6/l
1.70
108
847
465
3919
1.36
5.19
6.6
5.1
34.77
35.02
g/l
0.39
445
3664
131
875
1.57
5.17
2.2
2.3
0.21
0.20
g/l
0.21
117
800
609
5356
1.37
5.13
6.4
5.0
24.00
2720.87
e6/l
—
8
93
309
2446
1.39
5.09
8.5
6.3
—
—
—
0
0
406
3360
1.36
5.06
3.8
3.7
6.29
6.24
ph
0.39
192
1881
618
5459
1.36
5.00
6.0
4.7
—
2.60
—
0
11
432
3618
1.35
4.95
2.8
2.4
79.43
78.46
nmol/l
0.29
388
3190
123
819
1.57
4.92
1.7
1.5
—
—
—
0
0
365
2983
1.36
4.89
3.7
3.3
7.54
7.41
mmol/l
0.23
317
2497
143
995
1.51
4.69
2.0
1.7
—
—
—
0
0
55
298
1.90
4.61
3.1
3.5
1.13
3.91
ratio
1.62
31
179
121
818
1.55
4.53
7.2
8.1
—
—
—
0
0
36
169
2.17
4.45
1.2
1.2
—
—
—
0
0
292
2339
1.35
4.36
4.0
3.3
—
0.00
estimate
—
0
12
110
735
1.56
4.34
1.5
1.4
—
—
—
0
0
215
1640
1.40
4.34
1.3
1.3
2.28
1.41
u/ml
0.41
46
436
354
2921
1.33
4.33
3.7
3.4
63.35
46.96
mg/l
0.51
239
1875
74
448
1.71
4.32
1.7
1.7
1.63
1.58
g/l
0.19
58
399
573
5061
1.32
4.31
5.8
5.3
6.84
6.83
mmol/l
0.06
552
4834
88
559
1.63
4.28
1.2
1.2
—
—
—
0
0
416
3524
1.32
4.19
15.0
12.4
0.00
0.00
e9/l
0.68
339
2875
155
1121
1.46
4.19
6.3
8.0
7.41
7.42
ph
0.22
78
647
111
751
1.54
4.14
2.5
2.0
391.48
377.74
nmol/l
0.27
106
691
155
1127
1.45
4.07
6.2
7.9
5.09
5.11
kpa
0.13
149
1086
454
3903
1.31
4.07
2.4
2.2
94.34
94.36
pmol/l
0.00
236
2053
155
1128
1.45
4.05
6.2
7.9
11.94
11.91
kpa
0.02
149
1089
157
1148
1.44
4.00
1.3
1.3
—
—
—
0
0
152
1115
1.43
3.80
6.3
8.0
0.41
1.08
mmol/l
1.00
121
919
223
1748
1.36
3.77
4.3
4.2
754.60
396.56
ng/l
0.29
188
1468
358
3004
1.30
3.76
4.4
4.1
12.45
8.38
mg/mmol
0.58
237
1880
189
1444
1.38
3.74
3.7
3.2
2.11
2.19
e6/l
0.05
88
733
134
963
1.45
3.74
1.4
1.3
—
—
—
0
0
18
67
2.72
3.67
1.1
1.0
3.77
3.14
u/ml
—
10
31
93
624
1.54
3.62
7.4
9.3
93.61
93.96
%
0.17
93
619
164
1233
1.40
3.57
7.4
5.4
1.03
1.03
mmol/l
0.01
156
1135
20
80
2.53
3.56
1.1
1.1
3.81
2.63
u/ml
0.19
11
45
90
602
1.55
3.56
7.5
9.4
0.60
0.65
%
0.43
90
596
14
46
3.07
3.54
1.0
1.0
0.23
0.43
u/ml
—
7
18
487
4276
1.28
3.53
17.3
16.6
1.32
1.30
inr
0.24
396
3584
22
93
2.40
3.50
2.1
2.4
—
—
—
0
0
6
6
10.05
3.50
1.0
1.2
—
—
—
0
0
113
797
1.47
3.48
2.2
3.0
65.85
66.77
g/l
0.52
102
728
52
304
1.75
3.48
3.5
3.5
1331.22
273.88
mg/l
0.47
23
125
301
2490
1.30
3.47
4.2
3.4
0.35
0.53
e6/l
1.22
218
1865
57
344
1.70
3.41
2.1
2.4
11.12
10.92
g/l
0.09
49
305
29
141
2.09
3.35
1.4
1.4
—
—
—
0
0
343
2899
1.28
3.33
4.3
3.5
24.04
102.18
e6/l
2.51
258
2259
27
128
2.14
3.32
1.3
1.4
163.13
170.23
au/ml
—
8
36
327
2748
1.29
3.31
2.4
2.2
213.04
227.35
u/l
0.13
309
2601
17
65
2.64
3.31
1.1
1.0
0.23
3.28
u/ml
—
7
24
99
687
1.49
3.31
4.5
3.6
110.87
93.06
ng/l
0.87
84
588
482
4249
1.27
3.30
4.7
4.1
0.05
3.77
estimate
0.79
99
930
41
228
1.83
3.25
1.3
1.2
120.00
90.50
titre
—
5
20
169
1297
1.37
3.24
2.1
2.1
—
—
—
0
0
326
2745
1.28
3.24
3.0
2.6
—
—
—
0
0
43
243
1.81
3.24
1.7
1.8
6827.25
15448.23
e6/l
1.47
32
172
135
1000
1.41
3.20
3.7
3.3
7.37
7.38
ph
0.49
80
584
314
2635
1.28
3.20
1.8
1.7
20.04
20.28
nmol/l
0.11
268
2206
136
1010
1.40
3.18
3.7
2.9
10.80
8.84
umol/l
0.29
117
909
38
208
1.86
3.17
1.1
1.2
—
—
—
0
0
91
628
1.50
3.13
7.1
9.1
1.28
1.30
%
0.05
91
621
475
4197
1.26
3.13
4.7
4.1
0.00
0.00
estimate
-0.00
97
906
150
1141
1.37
3.04
2.4
2.6
1.79
1.81
%
0.10
136
1018
483
4286
1.25
3.03
4.7
4.1
0.00
0.36
estimate
0.53
91
873
39
219
1.81
3.01
1.5
1.2
2.07
2.52
u/ml
—
6
26
371
3196
1.26
3.01
5.1
4.1
54.08
138.36
e6/l
2.12
267
2329
210
1683
1.32
3.01
1.9
1.8
1113.11
1189.32
nmol/l
0.63
163
1243
41
234
1.79
3.01
4.2
3.2
13.26
1.61
index
0.57
19
127
164
1270
1.35
2.97
1.4
1.3
14.89
14.94
u/ml
0.00
53
466
319
2707
1.27
2.92
3.2
2.7
56.03
91.43
u/l
0.63
293
2505
11
32
3.46
2.90
1.9
2.9
0.61
0.60
mmol/l
0.13
11
32
93
662
1.45
2.76
2.2
2.6
—
—
—
0
0
14
54
2.62
2.71
1.1
1.1
5.70
1.81
u/ml
—
7
26
128
970
1.37
2.67
3.7
3.2
1.83
2.06
mmol/l
0.26
112
823
17
73
2.35
2.66
2.1
2.6
1896.82
857.79
mg
0.70
17
73
31
169
1.86
2.65
1.5
1.2
35.42
36.35
u/ml
—
6
17
220
1803
1.28
2.65
1.8
1.7
1.42
1.39
mg/l
0.06
177
1425
433
3836
1.23
2.64
3.3
2.9
—
—
estimate
—
0
0
11
36
3.08
2.57
1.3
1.3
8.57
6.34
ug/l
0.60
11
30
21
102
2.08
2.48
4.0
2.4
0.76
1.07
g/24h
0.40
14
57
86
617
1.43
2.47
4.0
3.6
7.41
7.42
ph
0.16
75
518
46
288
1.63
2.47
1.3
1.2
—
—
—
0
0
63
428
1.50
2.39
4.0
3.7
—
—
—
0
0
103
768
1.38
2.38
2.2
2.1
0.00
0.02
estimate
0.50
20
138
21
104
2.04
2.37
1.2
1.7
70.13
64.38
%
—
8
69
131
1021
1.33
2.29
1.4
1.5
—
—
—
0
0
106
801
1.36
2.27
2.4
2.5
6.42
7.38
ug/l
0.29
86
700
58
392
1.51
2.26
2.3
2.1
0.00
2.37
estimate
0.50
17
106
345
3023
1.22
2.26
3.4
3.2
1909.12
1627.59
ng/l
0.47
303
2614
392
3482
1.21
2.23
4.5
4.2
39.69
89.18
ng/l
1.14
289
2698
80
582
1.41
2.15
5.9
8.1
24.29
24.92
mmol/l
1.06
80
577
24
130
1.87
2.14
1.3
1.2
271.74
317.67
u/ml
0.40
19
75
342
3015
1.21
2.07
3.8
3.5
2.35
2.35
mmol/l
0.07
306
2711
15
70
2.16
1.99
1.0
1.2
116.00
98.21
pmol/l
0.35
15
70
16
78
2.07
1.91
1.2
1.4
27.27
30.50
%
—
7
51
538
4966
1.19
1.90
3.9
3.4
63.02
55.48
u/l
0.73
506
4611
237
2031
1.22
1.90
3.1
2.7
4.67
4.85
e6/l
0.08
217
1868
14
65
2.17
1.88
1.1
1.1
0.32
1.24
u/ml
—
8
34
165
1367
1.25
1.81
1.4
1.3
34.49
38.19
iu/ml
0.14
47
421
231
2667
0.82
1.81
3.3
3.4
—
—
—
0
0
198
1676
1.23
1.79
4.3
5.0
—
—
—
0
0
20
109
1.85
1.78
1.2
1.1
1.61
1.58
g/l
0.14
20
94
93
718
1.33
1.77
3.5
4.4
0.70
0.59
%
0.15
23
238
62
449
1.41
1.75
4.7
4.2
36.93
36.89
°c
0.29
62
444
94
730
1.32
1.72
3.9
4.8
0.00
0.13
%
1.86
19
202
13
61
2.15
1.72
1.2
1.2
—
—
—
0
0
736
7013
1.20
1.71
6.1
5.3
1.93
1.98
mu/l
0.56
682
6389
12
55
2.20
1.68
1.0
1.1
2.26
2.29
u/ml
—
7
27
10
40
2.52
1.67
1.2
1.4
27.00
30.66
umol/l
—
10
34
65
480
1.38
1.65
1.5
1.4
—
—
—
0
0
110
878
1.29
1.65
2.3
2.8
68.73
69.28
e9/l
0.06
79
664
10
44
2.29
1.56
1.1
1.0
—
—
—
0
0
24
145
1.67
1.55
2.2
2.0
1.93
1.66
mmol/l
0.66
24
140
13
64
2.05
1.54
2.8
3.0
34.83
39.69
%
—
6
39
13
64
2.05
1.54
1.1
1.1
—
—
—
0
0
28
178
1.59
1.50
1.5
1.2
—
—
—
0
0
83
648
1.31
1.49
2.8
2.8
11.28
10.96
g/l
0.21
78
597
10
45
2.23
1.46
1.0
1.2
128.60
138.76
nmol/l
—
10
45
90
713
1.29
1.45
3.6
4.5
0.06
0.14
%
0.60
17
210
299
2678
1.17
1.44
4.8
3.4
36.29
34.60
u/l
0.14
284
2526
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
12
59
2.05
1.44
1.1
1.1
—
—
—
0
0
9
39
2.32
1.43
1.2
1.2
—
0.88
%
—
0
8
77
599
1.31
1.43
4.4
5.5
—
—
—
0
0
212
1847
1.19
1.42
4.0
3.0
2.48
2.46
mmol/l
1.02
186
1656
15
81
1.87
1.40
3.6
3.4
90.60
11.82
index
—
10
50
17
96
1.78
1.39
1.4
1.3
—
—
—
0
0
203
1766
1.19
1.38
3.6
3.0
526.65
536.11
mosm/kgh2o
0.26
179
1556
15
82
1.84
1.36
1.0
1.1
—
—
—
0
0
94
757
1.27
1.35
3.6
4.4
1.05
0.97
%
0.06
22
254
781
7532
1.19
1.34
26.3
18.3
27.80
26.90
mg/l
0.29
705
6347
21
128
1.65
1.34
1.3
1.0
—
—
—
0
0
92
742
1.26
1.31
1.7
1.5
—
—
—
0
0
56
424
1.34
1.27
2.3
3.6
4.23
4.45
pmol/l
0.74
44
377
53
399
1.35
1.25
1.2
1.3
—
—
—
0
0
13
70
1.87
1.24
1.3
1.4
—
—
—
0
0
26
173
1.52
1.19
1.0
1.2
15.27
37.42
u/l
1.43
21
149
8
38
2.11
1.18
1.1
2.7
580.88
1782.16
u/ml
—
8
38
10
50
2.01
1.16
1.1
1.1
—
—
—
0
0
10
50
2.01
1.16
4.0
3.5
0.80
0.92
index
—
10
50
616
5865
1.14
1.15
5.1
4.2
14.99
14.99
pmol/l
0.00
569
5296
66
520
1.29
1.15
1.5
1.7
1.30
1.57
g/l
0.61
58
478
31
216
1.45
1.15
1.9
1.6
—
—
—
0
0
732
7054
1.15
1.13
4.9
4.5
1.36
1.30
mmol/l
1.34
675
6377
10
51
1.97
1.11
1.9
3.4
84.40
129.20
nmol/l
—
10
51
32
226
1.43
1.11
2.2
2.1
122.25
127.91
g/l
0.57
20
176
7
31
2.27
1.10
1.6
3.2
—
—
—
0
0
63
497
1.29
1.10
1.3
1.2
—
—
—
0
0
243
2186
1.15
1.09
3.5
3.2
0.00
0.03
—
5
73
119
1010
1.20
1.08
3.3
4.4
3.40
25.67
ug/l
1.97
97
848
13
74
1.77
1.07
1.1
1.1
—
—
—
0
0
22
145
1.53
1.06
1.2
1.1
—
—
—
0
0
34
246
1.40
1.05
14.8
11.3
—
—
—
0
0
264
2399
1.14
1.02
5.1
4.2
0.00
0.01
estimate
0.78
87
817
28
198
1.43
0.98
2.7
2.7
15.99
15.98
%
0.00
28
192
7
36
1.95
0.97
1.9
1.9
—
—
—
0
0
10
54
1.86
0.97
1.1
1.4
—
—
—
0
0
9
51
1.77
0.94
3.1
1.6
—
—
—
0
0
7
37
1.90
0.94
1.7
3.1
—
—
—
0
0
10
55
1.83
0.92
1.4
1.6
11.92
14.05
umol/l
—
10
50
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
16
241
0.66
0.88
4.8
4.7
—
—
—
0
0
10
56
1.79
0.88
1.5
1.7
41.51
35.30
%
—
10
56
14
87
1.62
0.88
1.1
1.2
—
—
—
0
0
54
433
1.26
0.86
2.5
2.4
—
—
—
0
0
34
256
1.34
0.86
1.4
1.5
286.50
272.65
ug/g
0.17
24
152
757
7358
1.13
0.85
5.6
5.3
1.43
1.45
mmol/l
0.56
702
6703
35
265
1.33
0.85
4.4
4.0
3.95
3.93
mmol/l
0.08
35
259
747
7257
1.13
0.84
8.0
7.0
40.82
40.17
mmol/mol
1.20
702
6720
20
138
1.46
0.82
1.2
1.1
—
—
—
0
0
809
7903
1.14
0.81
17.1
12.8
26.97
25.76
u/l
0.74
791
7646
14
89
1.58
0.81
3.9
2.2
—
—
—
0
0
54
437
1.25
0.81
1.2
1.2
41.71
109.85
u/ml
2.41
14
161
10
58
1.73
0.80
2.2
2.2
4.04
3.75
ug/l
—
10
53
33
251
1.33
0.79
1.8
1.6
13.50
17.63
u/ml
—
7
48
294
2730
1.11
0.78
4.8
3.4
—
—
—
0
0
638
6157
1.11
0.78
33.1
22.8
14.06
13.83
%
3.47
633
6068
10
59
1.70
0.76
2.1
2.1
3.52
2.03
ug/l
—
10
51
39
307
1.28
0.74
1.8
1.8
20.12
20.57
s
0.36
34
284
26
193
1.36
0.73
4.3
5.2
1.76
2.75
mmol/l
1.22
20
135
46
371
1.25
0.73
5.1
3.7
137.82
10609.94
u/ml
0.81
39
320
94
817
1.17
0.70
5.3
4.3
7.33
7.36
ph
0.34
70
592
56
464
1.22
0.70
2.5
3.3
25.04
25.20
mmol/l
0.14
56
447
14
93
1.51
0.69
1.2
1.3
—
—
—
0
0
759
7408
1.11
0.69
5.8
5.4
4.45
4.53
mmol/l
1.43
714
6813
803
7863
1.12
0.68
29.8
22.1
139.42
139.61
mmol/l
1.23
791
7706
7
43
1.63
0.67
3.4
1.7
—
—
—
0
0
13
86
1.52
0.66
1.3
1.3
—
—
—
0
0
5
28
1.79
0.66
1.2
1.1
—
21.33
—
0
6
772
7548
1.11
0.66
6.8
6.2
2.55
2.62
mmol/l
1.22
722
6902
7
44
1.60
0.65
1.4
2.0
10.89
19.19
nmol/l
—
7
38
26
198
1.32
0.64
1.1
1.1
—
—
—
0
0
5
29
1.73
0.64
1.4
1.5
2.04
1.87
umol/l
—
5
23
803
7871
1.12
0.64
30.3
22.3
4.00
4.00
mmol/l
0.00
790
7700
817
8018
1.12
0.62
33.1
24.3
86.19
81.38
umol/l
1.71
807
7908
18
130
1.39
0.61
1.7
2.5
—
—
—
0
0
16
113
1.42
0.61
1.2
1.5
—
—
—
0
0
17
122
1.40
0.60
2.9
2.7
—
—
—
0
0
756
7397
1.10
0.59
6.1
5.5
6.13
6.07
mmol/l
0.66
699
6684
783
7675
1.10
0.58
20.8
16.5
—
—
—
0
0
15
106
1.42
0.58
1.2
1.2
1.86
6.09
u/ml
—
7
43
6
36
1.67
0.56
2.3
1.7
20.23
57.20
u/l
—
6
36
27
212
1.28
0.56
3.6
2.8
88.60
88.82
%
0.05
27
204
24
186
1.30
0.54
1.3
1.3
—
—
—
0
0
6
38
1.58
0.54
2.2
1.3
48.13
25.78
umol/l
—
6
32
9
60
1.50
0.54
2.2
1.8
142.44
103.71
ng/l
—
9
60
46
387
1.20
0.53
2.4
2.9
—
—
—
0
0
20
152
1.32
0.52
1.1
1.2
1.55
1.56
g/l
0.05
20
152
9
63
1.43
0.52
1.2
1.2
—
—
—
0
0
37
445
0.82
0.51
3.9
3.7
1.02
1.02
ratio
0.34
29
423
340
3238
1.08
0.51
1.9
2.0
1.36
1.33
mmol/l
0.42
289
2665
199
1859
1.09
0.48
5.3
4.4
1.02
1.02
kg/l
0.22
130
1265
16
119
1.35
0.48
1.2
1.5
—
—
—
0
0
209
2225
0.92
0.46
4.4
3.6
3.29
0.05
estimate
0.48
76
713
16
120
1.34
0.46
1.2
1.5
—
—
—
0
0
16
120
1.34
0.46
1.2
1.5
—
—
—
0
0
16
121
1.33
0.44
1.2
1.5
—
—
—
0
0
46
396
1.17
0.43
2.0
2.0
—
—
—
0
0
13
96
1.36
0.41
1.2
1.2
—
—
nmol/l
—
0
0
5
34
1.47
0.40
2.0
1.4
—
—
—
0
0
12
160
0.75
0.40
1.5
1.7
—
—
—
0
0
821
8104
1.08
0.39
37.9
27.6
246.38
244.57
e9/l
0.33
811
7931
20
160
1.26
0.38
1.6
1.8
—
—
—
0
0
11
80
1.38
0.38
1.3
1.1
—
—
—
0
0
14
181
0.77
0.38
2.6
1.2
3.88
785.40
e6/l
—
8
140
821
8106
1.08
0.38
37.7
27.5
92.03
91.62
fl
1.66
814
8004
821
8107
1.08
0.37
38.5
28.1
39.72
39.89
%
0.42
815
7998
821
8107
1.08
0.37
37.8
27.5
4.38
4.43
e12/l
1.94
812
7901
821
8107
1.08
0.37
37.7
27.4
30.53
30.43
pg
0.90
814
8004
821
8109
1.08
0.36
38.1
27.7
132.30
133.65
g/l
1.64
815
8002
821
8109
1.08
0.36
37.9
27.6
7.03
6.86
e9/l
0.95
812
7900
11
81
1.36
0.36
1.3
1.2
—
—
—
0
0
14
179
0.78
0.35
2.6
1.2
9.75
31.22
e6/l
—
8
134
13
99
1.32
0.35
1.0
1.2
—
—
u/ml
—
0
0
59
656
0.89
0.34
5.8
3.9
—
—
—
0
0
14
109
1.29
0.33
1.4
1.3
26.88
64.99
mu/l
0.82
14
99
14
109
1.29
0.33
1.2
1.6
—
—
—
0
0
36
413
0.87
0.33
1.6
1.8
3.23
3.45
mmol/l
0.57
25
312
22
183
1.21
0.32
2.4
1.8
2.57
4.26
iu/l
—
8
68
195
1856
1.06
0.31
2.0
1.8
432.79
27447525.17
pmol/l
1.66
171
1512
29
250
1.16
0.29
3.5
2.9
7.89
7.90
kpa
0.01
29
244
11
85
1.30
0.28
2.7
4.0
—
—
—
0
0
11
85
1.30
0.28
1.5
1.6
26.27
39.26
ng/l
0.38
11
85
34
299
1.14
0.27
1.1
1.1
—
—
—
0
0
28
243
1.16
0.27
1.4
1.7
—
—
—
0
0
70
759
0.92
0.27
1.4
1.5
—
—
—
0
0
8
67
1.20
0.26
2.5
1.7
—
—
—
0
0
8
67
1.20
0.26
1.3
1.1
—
—
—
0
0
9
72
1.25
0.25
2.0
1.3
—
—
—
0
0
6
85
0.70
0.24
1.0
1.2
—
—
—
0
0
5
41
1.22
0.22
1.8
1.7
32.48
53.06
ug/l
—
5
41
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
1.95
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
13.43
—
0
7
14
117
1.20
0.20
1.1
1.1
—
21.87
—
0
30
10
80
1.25
0.20
1.0
1.1
—
—
—
0
0
25
221
1.13
0.20
1.6
2.5
41.94
98.88
ug/min
1.12
11
121
18
155
1.16
0.20
1.8
1.2
—
—
—
0
0
20
174
1.15
0.19
1.6
3.0
52.40
58.52
%
0.95
20
174
15
127
1.18
0.19
1.3
2.6
29.93
32.50
pg
1.38
15
127
307
3147
0.96
0.19
5.5
5.5
5.49
3.25
ug/l
0.52
274
2826
34
308
1.11
0.19
1.8
1.7
0.22
0.35
mg/l
1.34
16
145
11
91
1.21
0.17
1.9
2.6
—
—
—
0
0
35
320
1.10
0.17
1.8
1.5
—
—
—
0
0
13
110
1.18
0.17
1.3
1.6
—
—
—
0
0
13
110
1.18
0.17
1.3
1.6
—
—
—
0
0
13
110
1.18
0.17
1.3
1.6
—
—
—
0
0
13
110
1.18
0.17
1.3
1.6
—
—
—
0
0
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
8
73
1.10
0.15
2.1
2.1
—
—
—
0
0
10
84
1.19
0.14
1.2
1.6
—
—
—
0
0
216
2109
1.03
0.13
1.4
1.4
—
—
—
0
0
105
1012
1.04
0.13
3.2
3.3
3.75
5.59
e9/l
2.10
92
875
13
114
1.14
0.12
1.5
1.3
20060.33
96093.49
e6/l
—
6
61
11
96
1.15
0.10
1.3
1.1
—
—
—
0
0
45
427
1.06
0.10
1.3
1.4
—
—
—
0
0
5
44
1.14
0.10
1.2
1.1
—
—
—
0
0
6
54
1.11
0.09
1.3
1.0
—
—
—
0
0
6
54
1.11
0.09
2.3
2.8
—
—
—
0
0
181
1843
0.98
0.08
3.8
3.3
0.66
0.80
ug/l
2.19
127
1236
5
60
0.83
0.08
3.0
1.6
—
—
—
0
0
5
65
0.77
0.08
1.4
2.6
10.52
8.63
mmol/l
—
5
65
6
74
0.81
0.07
2.8
2.4
—
—
—
0
0
6
75
0.80
0.07
1.2
1.2
—
—
—
0
0
74
718
1.03
0.07
4.8
3.9
1.23
1.22
mmol/l
0.34
68
617
17
184
0.92
0.07
6.3
3.9
25.15
30.34
mg/l
0.26
11
133
63
651
0.97
0.07
3.5
2.9
6.14
6.06
ph
0.28
38
458
10
112
0.89
0.07
1.4
1.4
—
—
—
0
0
15
139
1.08
0.05
1.6
3.0
4.07
4.38
e9/l
0.25
15
139
12
110
1.09
0.05
1.8
1.4
277.29
276.56
mosm/kgh2o
—
7
79
23
220
1.05
0.03
1.3
1.1
—
—
—
0
0
318
3162
1.01
0.03
5.0
4.1
0.01
0.04
estimate
0.85
80
761
10
92
1.09
0.03
1.0
1.1
—
—
—
0
0
17
178
0.95
0.02
1.9
1.2
3.84
3.79
mmol/l
0.08
17
167
19
198
0.96
0.02
1.3
1.2
—
—
—
0
0
10
94
1.06
0.01
1.2
1.2
—
—
—
0
0
11
106
1.04
0.00
1.5
1.3
—
—
—
0
0
14
142
0.99
0.00
1.5
1.4
259.55
224.18
miu/ml
—
6
65
11
107
1.03
0.00
1.5
1.3
—
—
—
0
0
13
129
1.01
0.00
1.5
1.3
2138.71
1470.27
e6/l
—
7
84
22
215
1.02
0.00
5.5
4.0
—
—
—
0
0
20
205
0.98
0.00
2.0
1.2
483.30
506.15
mg/l
0.13
20
193
11
105
1.05
0.00
1.3
1.1
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
43.00
41.32
mg/l
—
5
48
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.2
—
0.16
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
284.98
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
2.1
1.8
11.00
10.08
%
—
8
85
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
5
54
0.93
-0.00
1.0
1.1
209.80
253.71
mg/l
—
5
48
0
8
0.00
-0.00
0.0
1.0
—
104.00
—
0
8
6
61
0.98
-0.00
2.0
2.7
16.27
16.25
%
—
6
61

Mortality – FinRegistry

Association

Association between endpoint L12_OTHACUSKINSUNNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_OTHACUSKINSUNNAS 0.923 [0.74, 1.15] 0.471
Birth year 0.993 [0.98, 1.0] 0.128

During the follow-up period (1.1.1998 — 31.12.2019), 134 out of 829 females with L12_OTHACUSKINSUNNAS died.

Males

Parameter HR [95% CI] p-value
L12_OTHACUSKINSUNNAS 1.121 [0.91, 1.38] 0.29
Birth year 0.983 [0.97, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 194 out of 643 males with L12_OTHACUSKINSUNNAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_OTHACUSKINSUNNAS.

N-year risk Females Males
1 0.089% 0.185%
5 0.486% 1.079%
10 1.204% 2.838%
15 2.335% 5.413%
20 4.209% 9.097%

Relationships between endpoints

Index endpoint: L12_OTHACUSKINSUNNAS – Other and unspecified acute skin changes due to ultraviolet radiation

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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