phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.
Other acute skin changes due to ultraviolet radiation
DOID EFO Endpoint Browser PheWeb
L12_OTHACUSKINSUN
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
763 |
4. Check minimum number of eventsNone |
763 |
5. Include endpoints |
1477 |
6. Filter based on genotype QC (FinnGen only) |
1342 |
Control definitions (FinnGen only)
- Control exclude
- L12_RADIATIONRELATEDSKIN
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L55-L59
- Name in latin
- Aliae commutationes acutae cutis e radiatione ultraviolacea
Similar endpoints
↥List of similar endpoints to
Other acute skin changes due to ultraviolet radiation
based on the number of shared cases.
Similar with more cases:
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12305 | 6288 | 5855 |
| Only index persons | 8709 | 4853 | 3856 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.18 | 0.16 |
| Only index persons | 0.16 | 0.18 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 44.15 | 46.17 | 41.73 |
| Only index persons | 37.54 | 41.00 | 33.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1342 | 729 | 613 |
| Unadjusted period prevalence (%) | 0.27 | 0.26 | 0.28 |
| Median age at first event (years) | 41.73 | 42.20 | 41.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1381
- Matched controls
- 13810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
307.7
486
*
L56.4
ICD-10 Finland
Polymorphous light eruption
282.1
307.7
290
13
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
+∞
252.0
234
*
L57.0
ICD-10 Finland
Actinic keratosis
9.2
168.8
224
286
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.9
167.2
299
534
D07AB08
ATC
desonide; topical
5.0
124.5
324
803
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
17.3
105.4
88
54
TQW99
NOMESCO Finland
Other minor procedure on skin
7.6
103.5
156
228
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
21.7
98.4
74
36
69288
ICD-8 Finland
Other eczema and dermatitis, E causis alii definitis
+∞
92.8
88
*
L56.9
ICD-10 Finland
Acute skin change due to ultraviolet radiation, unspecified
196.9
89.4
92
5
ZXC20
NOMESCO Finland
Use of chemical agents
12.6
88.2
88
74
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.2
81.8
429
1687
E0000UV, ,
ATC
2.9
81.0
739
3939
D07AC01
ATC
betamethasone; topical
2.8
78.2
678
3500
E000001, ,
ATC
3.2
75.7
407
1615
D07AB02
ATC
hydrocortisone butyrate; topical
2.8
71.6
560
2713
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.0
69.3
223
634
XQ802
NOMESCO Finland
Epicutan test
6.0
68.0
127
230
D07AC13
ATC
mometasone; topical
2.7
64.6
540
2676
L56.3
ICD-10 Finland
Solar urticaria
219.8
61.6
63
*
69283
ICD-8 Finland
Other eczema and dermatitis, Dysidroticum (pompholyx)
+∞
57.7
55
*
L56.2
ICD-10 Finland
Photocontact dermatitis [berloque dermatitis]
125.4
56.3
60
5
D07AA02
ATC
hydrocortisone; topical
3.1
54.4
278
1052
R06AE07
ATC
cetirizine; oral
2.3
48.3
685
4169
E000002, ,
ATC
3.2
48.1
216
755
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
13.2
47.9
46
36
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.2
45.5
198
678
H02AB06
ATC
prednisolone; systemic
2.2
44.2
770
5030
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
10.5
44.2
49
48
L20.0
ICD-10 Finland
Besnier prurigo
3.8
43.1
142
406
ZXC50
NOMESCO Finland
Cryotherapy
10.1
40.2
46
47
P01BA02
ATC
hydroxychloroquine; oral
3.2
40.1
174
593
L57.8
ICD-10 Finland
Other skin changes due to chronic exposure to nonionizing radiation
200.5
38.0
39
*
69280
ICD-8 Finland
Other eczema and dermatitis, E radiatione solari
+∞
36.6
35
*
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
8.2
36.4
49
62
D07AD01
ATC
clobetasol; topical
2.4
36.0
290
1360
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
9.4
35.8
43
47
EAA10
NOMESCO Finland
Excision of lesion of lip
8.6
35.7
46
55
L30.3
ICD-10 Finland
Infective dermatitis
4.4
34.5
89
212
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.6
34.4
235
1019
D07BC01
ATC
betamethasone and antiseptics; topical
2.6
33.5
220
935
N05BB01
ATC
hydroxyzine; systemic
3.3
33.3
135
440
L56.0
ICD-10 Finland
Drug phototoxic response
334.8
33.0
33
*
TQW80
NOMESCO Finland
Local dermatologic skincare
5.8
32.4
60
107
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
8.6
31.9
41
49
ZXC10
NOMESCO Finland
Use of laser
5.4
31.0
62
119
XQ800
NOMESCO Finland
Prick test
3.1
30.8
138
477
D11AH01
ATC
tacrolimus; topical
10.2
28.3
32
32
E000003, ,
ATC
3.6
26.7
90
260
R06AX27
ATC
desloratadine; oral
1.9
25.5
400
2395
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.8
25.3
80
221
D02AX
ATC
Other emollients and protectives
4.4
24.6
63
149
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
24.3
94
297
D07XC01
ATC
betamethasone; topical
2.3
23.9
202
955
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
31.7
23.8
31
10
E000007, ,
ATC
3.2
23.5
97
319
XQ848
NOMESCO Finland
Dermatological photography
4.5
23.1
57
131
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
6.9
20.9
32
47
69200
ICD-8 Finland
Other eczema and dermatitis, Due to detergents
78.0
20.7
23
*
E000006, ,
ATC
2.7
20.6
117
459
D07CC01
ATC
betamethasone and antibiotics; topical
2.2
20.4
199
995
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
27.5
20.1
27
10
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
6.4
19.8
33
53
R06AE09
ATC
levocetirizine; oral
2.1
19.3
204
1051
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.1
19.1
40
80
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
18.9
329
2009
D07XB05
ATC
dexamethasone; topical
3.9
18.9
56
148
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.2
18.7
74
237
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
192.5
18.6
19
*
H02AB07
ATC
prednisone; oral
2.0
18.4
217
1163
XQ806
NOMESCO Finland
Minimal Erythema Dose (MED) test
182.2
17.5
18
*
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
7.9
17.5
24
31
D05BB02
ATC
acitretin; oral
4.2
17.4
47
116
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
17.3
284
1699
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
17.0
64
199
S29
ICPC
Skin symptom/complaint other
1.8
17.0
283
1700
6927F
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERUPTIO POLYMORPHICA SOLARIS]
+∞
16.7
16
*
J01FF01
ATC
clindamycin; systemic
1.7
16.6
382
2516
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
7.4
16.6
24
33
R06AX22
ATC
ebastine; oral
1.9
16.5
244
1411
L93.0
ICD-10 Finland
Discoid lupus erythematosus
13.0
16.2
28
22
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
18.8
16.0
24
13
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
26.6
15.6
21
8
L04AX03
ATC
methotrexate; systemic
2.2
15.6
147
723
D09AB01
ATC
zinc bandage without supplements; topical
4.3
15.3
39
92
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
45.5
15.1
18
*
D06BX01
ATC
metronidazole; topical
2.1
15.1
159
816
N02AX02
ATC
tramadol; systemic, rectal
1.6
14.9
597
4493
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
14.6
287
1801
L71.8
ICD-10 Finland
Other rosacea
4.6
14.5
34
75
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
14.3
259
1587
ZQZ00
NOMESCO Finland
Treatment of several skin areas
27.5
14.3
19
7
EAA30
NOMESCO Finland
Partial excision of lower lip
27.5
14.3
19
7
R03DC03
ATC
montelukast; oral
1.8
14.2
225
1324
D02AE01
ATC
carbamide; topical
2.4
14.2
96
410
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.2
13.7
119
565
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
6.4
13.3
22
35
S21
ICPC
Skin texture symptom/complaint
1.8
13.2
204
1191
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.1
408
2874
L04AX01
ATC
azathioprine; systemic
2.9
13.0
63
227
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
13.0
125
618
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.9
468
3414
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
22.8
12.9
18
8
L01BC02
ATC
fluorouracil; systemic, topical
22.8
12.9
18
8
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.4
12.9
88
377
J01DB01
ATC
cefalexin; oral
1.7
12.9
1083
9497
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
50.5
12.9
15
*
L30.0
ICD-10 Finland
Nummular dermatitis
2.8
12.7
65
242
Z3231
NOMESCO Finland
Registered nurse
1.6
12.6
367
2543
L56.1
ICD-10 Finland
Drug photoallergic response
131.2
12.5
13
*
J01AA04
ATC
lymecycline; systemic
1.9
12.4
170
955
T78.4
ICD-10 Finland
Allergy, unspecified
2.7
12.2
66
253
R06AX13
ATC
loratadine; oral
1.8
12.0
193
1138
L50.3
ICD-10 Finland
Dermatographic urticaria
3.8
11.8
35
93
R03AC02
ATC
salbutamol; inhalant
1.5
11.3
715
5812
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
10.6
11.3
21
20
R03AC03
ATC
terbutaline; inhalant
1.8
11.2
185
1100
D05AX52
ATC
calcipotriol, combinations; topical
2.4
11.2
74
313
L71.9
ICD-10 Finland
Rosacea, unspecified
3.2
11.2
43
136
Z01.2
ICD-10 Finland
Dental examination
1.5
11.1
562
4369
ZXC15
NOMESCO Finland
Use of photodynamic technique
11.3
11.1
20
18
M54.5
ICD-10 Finland
Low back pain
1.5
11.0
472
3542
D07AC14
ATC
methylprednisolone aceponate; topical
2.4
10.9
74
316
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
3.0
10.8
47
160
D05AX02
ATC
calcipotriol; topical
2.7
10.8
57
216
S18
ICPC
Laceration/cut
1.5
10.8
602
4761
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
28.3
10.7
14
5
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
10.6
162
939
R03BB04
ATC
tiotropium bromide; inhalant
1.8
10.6
161
933
Z71.8
ICD-10 Finland
Other specified counselling
1.5
10.6
424
3135
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.5
10.5
25
56
XQ815
NOMESCO Finland
Photoprovocation test
+∞
10.4
10
*
M25.5
ICD-10 Finland
Pain in joint
1.5
10.4
422
3125
A46
ICD-10 Finland
Erysipelas
1.7
10.4
207
1296
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
10.4
91
435
L57.9
ICD-10 Finland
Skin changes due to chronic exposure to nonionizing radiation, unspecified
32.8
10.3
13
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.2
10.3
84
389
L50.8
ICD-10 Finland
Other urticaria
3.5
10.2
34
98
S76
ICPC
Skin infection other
2.3
10.2
81
372
J01DA01
ATC
[U] cefalexin
1.5
10.2
812
6844
J01AA07
ATC
tetracycline; systemic
1.7
10.1
185
1131
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
11.4
10.1
18
16
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.1
457
3459
69230
ICD-8 Finland
Other eczema and dermatitis, Due to drugs
40.4
10.0
12
*
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
26.2
9.8
13
5
11006
ICD-8 Finland
Dermatophytosis, Pedis
26.2
9.8
13
5
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.4
9.7
68
295
D07AB01
ATC
clobetasone; topical
2.6
9.7
54
210
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
9.7
148
859
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
9.6
197
1243
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
4.6
9.5
22
48
L17
ICPC
Foot/toe symptom/complaint
1.5
9.5
393
2913
M79.6
ICD-10 Finland
Pain in limb
1.4
9.4
561
4460
J01MA12
ATC
levofloxacin; systemic
1.6
9.4
251
1692
L26
ICD-10 Finland
Exfoliative dermatitis
21.9
9.4
13
6
ZZR00
NOMESCO Finland
Flap of skin
3.3
9.3
34
104
R03BA05
ATC
fluticasone; inhalant
1.6
9.3
230
1520
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.2
372
2741
J01FA06
ATC
roxithromycin; oral
1.4
9.2
508
3978
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
4.5
9.1
22
50
R03AK08
ATC
formoterol and beclometasone; inhalant
2.3
9.0
67
299
J01DA09
ATC
[U] cefadroxil
1.5
8.9
333
2412
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
8.8
262
1808
R03BA01
ATC
beclometasone; inhalant
1.7
8.8
186
1182
J01AA02
ATC
doxycycline; systemic
1.5
8.7
1020
9092
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
14.1
8.7
14
10
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
8.7
58
247
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
8.6
254
1747
A01AC01
ATC
triamcinolone; local oral
3.8
8.6
26
70
C03CA01
ATC
furosemide; systemic
1.4
8.6
430
3295
N06AX11
ATC
mirtazapine; oral
1.4
8.5
437
3362
M79.7
ICD-10 Finland
Fibromyalgia
2.5
8.5
51
206
D06BB10
ATC
imiquimod; topical
2.4
8.5
57
243
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.5
348
2566
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
20.2
8.5
12
6
F29
ICPC
Eye symptom/complaint other
1.8
8.5
137
808
A02BC03
ATC
lansoprazole; oral
1.5
8.4
376
2817
A01AB09
ATC
miconazole; local oral
1.9
8.4
114
637
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
8.4
618
5065
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
4.9
8.4
18
37
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
8.4
166
1037
D11AX14
ATC
[U] tacrolimus
9.5
8.3
16
17
R96
ICPC
Asthma
1.8
8.3
131
768
J02AC01
ATC
fluconazole; systemic
1.4
8.2
464
3631
R42
ICD-10 Finland
Dizziness and giddiness
1.5
8.2
301
2171
J01FA01
ATC
erythromycin; systemic
1.7
8.1
157
974
N05CF01
ATC
zopiclone; oral
1.4
8.1
426
3289
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
8.0
369
2777
N03AX16
ATC
[U] pregabalin
1.5
8.0
294
2119
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.0
447
3488
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.7
8.0
164
1034
N03AX12
ATC
[U] gabapentin; oral
1.6
7.9
210
1408
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
7.9
124
724
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.9
550
4453
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
7.8
7.9
17
22
L20
ICD-10 Finland
Atopic dermatitis
2.9
7.8
36
127
R03BA02
ATC
budesonide; inhalant
1.6
7.8
227
1555
S87
ICPC
Dermatitis/atopic eczema
2.9
7.8
35
122
R04.0
ICD-10 Finland
Epistaxis
1.9
7.8
104
579
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
7.7
222
1518
R01AD08
ATC
fluticasone; nasal
1.5
7.7
337
2511
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
4.4
7.7
19
44
70908
ICD-8 Finland
Other diseases of skin, Alii definiti
25.2
7.6
10
*
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
7.5
96
526
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.1
7.5
30
98
L08
ICPC
Shoulder symptom/complaint
1.5
7.4
288
2094
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
7.4
89
478
L43.9
ICD-10 Finland
Lichen planus, unspecified
3.0
7.4
31
104
J01MA14
ATC
moxifloxacin; systemic
1.8
7.3
120
710
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
2.4
7.3
48
203
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
3.0
7.3
32
110
L56
ICD-10 Finland
Other acute skin changes due to ultraviolet radiation
+∞
7.3
7
*
6929A
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA NUMMULARE]
+∞
7.3
7
*
6927X
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[DERMATITIS PHOTOTOXICA NUD]
+∞
7.3
7
*
Z2221
NOMESCO Finland
Medical doctor
1.4
7.2
335
2518
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.1
7.2
69
342
L16
ICPC
Ankle symptom/complaint
1.7
7.2
149
940
R01AD09
ATC
mometasone; nasal
1.4
7.2
533
4343
E000004, ,
ATC
3.2
7.2
28
90
D11AX15
ATC
[U] pimecrolimus
30.2
7.2
9
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.1
537
4382
69009
ICD-8 Finland
Seborrhoeic dermatitis, Unspecified
20.1
7.1
10
5
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.1
338
2552
XQ845
NOMESCO Finland
Dermatoscopy
3.8
7.1
21
56
D02BB01
ATC
betacarotene; oral
12.1
7.1
12
10
L50.9
ICD-10 Finland
Urticaria, unspecified
2.3
7.1
49
213
C07AB07
ATC
bisoprolol; oral
1.4
7.1
640
5375
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.0
281
2055
L04AB04
ATC
adalimumab; parenteral
3.0
7.0
30
102
A02BC05
ATC
esomeprazole; systemic
1.4
7.0
503
4074
UJF32
NOMESCO Finland
Coloscopy
1.4
6.9
332
2513
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.9
866
7635
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
6.9
67
335
C08CA05
ATC
nifedipine; systemic
1.9
6.8
84
455
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
6.8
204
1404
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.7
213
1484
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.7
113
674
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.7
275
2017
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
6.7
47
205
L43.8
ICD-10 Finland
Other lichen planus
3.1
6.6
27
89
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.6
318
2403
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
6.6
243
1746
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.5
203
1409
WYA10
NOMESCO Finland
Emergency care or similar visit
1.9
6.5
86
477
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.5
166
1102
D06AX01
ATC
fusidic acid; topical
1.7
6.5
114
688
R83
ICPC
Respiratory infection other
1.4
6.5
270
1986
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.5
192
1319
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.5
798
6981
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.4
165
1097
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
70.2
6.4
7
*
6924B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS ALLERGICA]
70.2
6.4
7
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
6.4
93
532
L50.0
ICD-10 Finland
Allergic urticaria
2.6
6.4
36
142
J45
ICD-10 Finland
Asthma
1.7
6.4
126
786
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.6
6.3
20
56
M01AH05
ATC
etoricoxib; oral
1.3
6.3
758
6594
-59
ICPC
Other therap proced/minor surg NEC
2.6
6.3
36
143
Z3226
NOMESCO Finland
Physiotherapist
1.5
6.3
223
1590
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
9.3
6.3
12
13
M79.1
ICD-10 Finland
Myalgia
1.5
6.3
178
1211
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.3
274
2033
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
6.3
82
454
K13.09
ICD-10 Finland
Disease of the lips UNS
18.1
6.3
9
5
Y1203, ,
ICD-8 Finland
+∞
6.3
6
*
6927A
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERYTHEMA SOLARE]
+∞
6.3
6
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.2
163
1089
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.2
482
3931
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
6.1
55
267
M03BX02
ATC
tizanidine; oral
1.3
6.1
743
6464
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
6.1
43
189
K13.78
ICD-10 Finland
Other change in the oral mucosa
2.6
6.1
34
134
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
8.6
6.1
12
14
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.0
6.1
64
330
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
6.0
105
633
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
129
468
2.94
26.38
2.2
2.0
14.16
8.32
iu/ml
0.44
40
118
99
354
2.94
20.72
1.4
1.2
21.51
27.11
u/ml
—
9
16
83
276
3.14
19.71
1.3
1.2
5.22
6.19
u/ml
0.07
11
18
114
453
2.65
19.54
1.3
1.2
0.74
0.98
u/ml
—
7
34
95
343
2.90
19.54
2.2
1.6
0.23
0.24
g/l
0.78
90
332
92
337
2.85
18.43
1.4
1.2
2.23
2.63
u/ml
0.28
19
34
92
338
2.84
18.33
1.4
1.2
2.25
7.62
u/ml
0.94
19
56
52
142
3.77
16.77
1.3
1.3
39.65
76.60
u/ml
—
6
8
75
260
2.99
16.59
1.3
1.2
47.54
53.20
u/ml
0.10
18
28
826
6719
1.57
14.48
12.5
9.5
4.12
4.17
e9/l
0.27
741
5846
452
3253
1.58
13.32
2.8
2.3
2.78
2.89
mg/l
0.39
395
2777
307
2074
1.62
11.56
3.1
3.3
0.82
0.82
mmol/l
0.12
286
1960
291
1947
1.63
11.38
2.9
2.5
2.33
2.30
g/l
0.42
276
1806
682
5505
1.47
11.10
7.3
6.5
1.21
1.21
mmol/l
0.58
644
5095
682
5521
1.46
10.84
3.8
3.1
136.37
130.80
ug/l
0.23
639
5121
140
771
1.91
10.79
1.5
1.2
574.93
187.29
u/ml
1.50
132
713
223
1411
1.69
10.79
2.7
2.4
147.41
122.77
ug/g
0.70
180
1136
981
8554
1.51
10.49
5.7
4.4
14.23
12.95
mm/h
1.68
933
7956
265
1794
1.59
9.74
3.1
2.5
21.30
22.33
%
0.64
253
1673
410
3059
1.48
9.61
3.2
2.7
347.06
344.71
umol/l
0.17
360
2676
755
6326
1.43
9.43
7.6
6.6
10.68
11.69
umol/l
1.32
722
6060
654
5355
1.42
9.22
2.9
2.5
78.93
77.97
nmol/l
0.38
599
4811
1010
8958
1.47
9.08
10.9
8.3
79.44
80.09
u/l
0.19
977
8498
297
2106
1.52
8.80
2.9
2.5
12.69
12.72
umol/l
0.03
283
1957
730
6130
1.40
8.71
7.7
7.2
1.21
1.21
mmol/l
0.22
647
5296
150
924
1.70
7.95
1.9
1.7
—
—
—
0
0
282
2017
1.50
7.95
1.4
1.3
14.72
13.16
u/ml
0.10
102
766
313
2291
1.47
7.86
1.5
1.5
2.61
2.50
g/l
0.35
175
1413
179
1165
1.62
7.66
3.0
2.4
37.48
36.97
u/l
0.04
147
969
878
7699
1.39
7.58
6.0
4.8
157.89
2234.88
e6/l
—
9
120
342
2581
1.43
7.24
1.4
1.3
1.59
1.57
u/ml
0.01
84
708
229
1605
1.51
7.06
2.1
1.8
—
—
—
0
0
711
6074
1.35
6.98
4.6
3.9
0.00
0.00
estimate
0.50
141
1297
718
6163
1.34
6.73
4.7
3.9
0.03
3.69
estimate
1.06
144
1333
722
6204
1.34
6.71
4.7
3.9
0.17
0.25
estimate
0.11
136
1256
505
4119
1.36
6.61
3.5
3.3
7.53
7.46
mmol/l
0.14
438
3488
217
1526
1.50
6.56
2.1
1.8
—
—
—
0
0
66
334
2.03
6.55
1.7
1.4
—
—
—
0
0
287
2135
1.43
6.50
2.3
1.9
—
—
—
0
0
637
5398
1.33
6.39
6.3
5.0
35.22
35.35
g/l
0.22
604
5066
472
3827
1.35
6.37
2.9
2.6
53.39
81.66
u/l
0.75
438
3554
467
3781
1.36
6.36
2.3
2.2
183.53
216.96
u/l
0.55
444
3590
285
2126
1.43
6.34
3.4
3.0
0.86
1.09
e6/l
0.91
149
1124
134
852
1.63
6.30
1.6
1.8
—
—
—
0
0
375
2947
1.37
6.13
2.7
2.4
—
—
—
0
0
288
2172
1.41
6.00
1.4
1.3
36.84
32.88
iu/ml
0.21
96
671
35
141
2.52
5.97
1.9
1.7
56.47
61.68
%
0.27
17
94
69
367
1.93
5.97
1.7
1.6
0.09
21.54
iu/ml
0.49
12
56
142
934
1.58
5.81
1.7
1.9
—
—
—
0
0
173
1190
1.52
5.80
2.2
2.3
0.21
0.21
g/l
0.05
157
1100
800
7066
1.31
5.73
5.5
5.2
6.74
6.72
mmol/l
0.05
768
6725
286
2172
1.40
5.70
1.9
1.8
1096.45
1180.94
nmol/l
0.92
226
1632
487
4022
1.33
5.65
4.2
4.0
10.08
8.28
mg/mmol
0.29
313
2508
164
1128
1.52
5.50
2.6
2.1
381.21
382.02
nmol/l
0.02
155
1043
25
89
2.84
5.42
1.2
1.1
—
—
—
0
0
76
433
1.80
5.34
2.3
2.9
—
—
—
0
0
60
318
1.93
5.28
2.0
1.7
6416.57
13234.59
e6/l
1.55
44
226
20
64
3.16
5.20
1.2
1.6
7.52
7.18
ug/l
0.09
20
53
628
5425
1.29
5.07
2.5
2.2
94.67
94.93
pmol/l
0.05
338
2841
201
1466
1.43
5.01
6.4
8.2
5.09
5.11
kpa
0.09
191
1415
201
1467
1.43
4.99
6.4
8.2
12.02
12.05
kpa
0.02
192
1418
74
429
1.77
4.93
2.9
3.7
41.68
50.47
mg/l
0.35
62
372
74
429
1.77
4.93
2.9
3.6
40.43
63.09
mg/l
0.91
62
372
27
106
2.58
4.90
1.2
1.2
—
—
—
0
0
418
3435
1.31
4.89
4.1
3.3
0.53
0.50
e6/l
0.07
309
2541
119
783
1.57
4.88
2.1
1.7
—
—
—
0
0
24
89
2.73
4.86
1.2
1.1
—
—
—
0
0
131
883
1.53
4.83
1.5
1.5
—
—
—
0
0
651
5678
1.28
4.77
16.1
15.4
1.29
1.27
inr
0.23
526
4752
25
96
2.63
4.74
1.2
1.1
—
—
—
0
0
198
1457
1.42
4.69
6.5
8.1
0.74
1.01
mmol/l
0.37
162
1199
23
86
2.70
4.59
1.2
1.1
—
—
—
0
0
499
4231
1.28
4.53
3.6
3.5
2.35
2.35
mmol/l
0.19
451
3830
525
4496
1.27
4.35
4.9
4.0
184.56
124.47
e6/l
0.19
378
3202
64
370
1.77
4.33
1.7
1.7
—
—
—
0
0
149
1056
1.46
4.32
2.1
2.9
66.43
66.77
g/l
0.18
135
970
301
2401
1.32
4.29
4.3
4.0
633.61
346.89
ng/l
0.29
230
1910
121
824
1.51
4.28
7.7
9.7
93.59
93.92
%
0.18
121
819
66
388
1.74
4.23
2.9
3.5
1.37
3.35
ratio
1.37
37
231
191
1426
1.39
4.16
4.3
4.2
240.54
248.55
u/l
0.35
178
1355
427
3581
1.28
4.16
1.8
1.7
20.21
20.41
nmol/l
0.10
367
3029
117
796
1.51
4.16
7.8
9.8
0.60
0.64
%
0.43
117
790
135
948
1.47
4.11
3.9
3.6
99.02
88.94
ng/l
0.56
115
822
53
296
1.82
4.04
1.1
1.2
—
—
—
0
0
74
455
1.66
4.04
2.2
2.1
217.55
444.21
ug/l
1.19
66
431
89
574
1.59
4.02
1.7
1.8
1.61
1.56
g/l
0.19
71
515
22
87
2.55
3.97
1.2
1.1
—
—
—
0
0
53
298
1.81
3.96
1.1
1.2
—
—
—
0
0
469
4002
1.26
3.91
4.2
3.4
22.24
89.75
e6/l
3.15
361
3075
17
59
2.90
3.90
1.4
3.1
471.35
1314.61
u/ml
1.20
17
59
231
1805
1.34
3.77
1.6
1.5
—
—
—
0
0
119
830
1.47
3.77
7.4
9.5
1.34
1.29
%
0.24
119
823
30
141
2.15
3.72
1.1
1.0
3.04
3.00
u/ml
0.01
17
65
38
196
1.97
3.70
1.2
1.1
1.92
2.02
u/ml
0.03
24
106
58
344
1.72
3.64
1.4
1.3
—
—
—
0
0
248
1971
1.31
3.59
3.6
3.1
2.51
2.38
e6/l
0.08
117
967
215
1676
1.33
3.57
6.5
5.4
1.02
1.03
mmol/l
0.21
205
1552
335
2781
1.27
3.46
3.0
2.7
5.75
5.73
e6/l
0.01
307
2542
130
945
1.41
3.33
3.1
2.8
11.09
10.82
g/l
0.25
124
876
185
1426
1.34
3.31
3.4
2.7
8.96
8.29
umol/l
0.12
161
1273
1099
10402
1.28
3.31
6.2
5.4
1.88
1.93
mu/l
0.64
1030
9590
303
2498
1.27
3.31
3.6
2.9
2.46
2.46
mmol/l
0.54
264
2239
445
3835
1.24
3.29
3.4
3.2
1669.14
1478.88
ng/l
0.38
388
3304
27
129
2.11
3.25
1.4
1.3
19878.24
118661.16
e6/l
1.06
17
89
167
1272
1.36
3.23
4.0
3.3
1.92
1.96
mmol/l
0.05
150
1078
398
3401
1.24
3.17
4.9
4.0
0.00
0.01
estimate
1.15
131
1195
101
708
1.46
3.15
3.8
3.5
1.14
1.98
mmol/l
1.31
81
521
62
392
1.61
3.10
2.0
2.3
0.00
0.00
g/l
-0.00
53
341
67
432
1.58
3.09
3.8
3.9
24.54
24.92
mmol/l
0.45
62
401
533
4705
1.22
3.08
4.3
4.0
34.51
76.44
ng/l
1.28
374
3432
63
401
1.60
3.06
2.0
2.3
0.00
0.01
g/l
0.50
56
359
137
1021
1.38
3.05
2.2
2.4
6.62
6.79
ug/l
0.05
114
905
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
63
402
1.59
3.04
2.6
2.7
0.30
0.36
iu/ml
0.91
43
216
70
458
1.56
3.03
1.9
2.3
10.74
10.61
g/l
0.07
61
411
70
462
1.54
2.93
2.1
2.5
0.64
1.19
g/l
0.71
60
402
75
503
1.52
2.92
2.0
2.3
2.94
3.00
g/l
0.25
66
458
29
149
1.97
2.91
1.5
1.4
—
—
—
0
0
58
367
1.61
2.90
2.1
2.4
0.00
0.00
g/l
-0.00
52
341
94
662
1.45
2.88
1.5
1.5
—
—
—
0
0
109
790
1.41
2.87
2.4
2.5
19.89
20.29
au/ml
—
8
70
28
143
1.98
2.86
1.5
1.4
—
—
—
0
0
29
150
1.95
2.86
1.5
1.4
—
—
—
0
0
29
150
1.95
2.86
1.5
1.4
—
—
—
0
0
28
144
1.96
2.81
1.5
1.4
—
—
—
0
0
28
144
1.96
2.81
1.5
1.4
—
—
—
0
0
315
2656
1.24
2.80
1.8
1.7
1.31
1.22
mg/l
0.21
250
2074
30
159
1.91
2.77
1.2
1.0
0.41
1.24
u/ml
1.17
18
78
35
196
1.81
2.73
1.3
1.4
160.56
156.95
au/ml
—
9
55
1156
11083
1.26
2.65
24.2
16.9
24.10
25.20
mg/l
0.54
1024
9245
36
206
1.77
2.63
1.3
2.1
4.31
5.04
mmol/24h
1.12
31
186
611
5524
1.19
2.62
3.1
2.8
—
—
estimate
—
0
0
12
41
2.94
2.62
1.8
3.0
0.61
0.61
mmol/l
0.01
12
41
25
127
1.99
2.61
3.5
4.3
—
—
—
0
0
26
134
1.96
2.61
1.1
1.1
1.51
3.67
u/ml
0.98
15
56
815
7560
1.19
2.59
3.9
3.4
55.68
51.42
u/l
0.51
768
7097
6
11
5.47
2.54
1.8
1.1
—
—
—
0
0
144
1115
1.33
2.53
7.6
6.9
11.17
10.26
mmol/l
0.75
139
1065
7
16
4.39
2.47
1.4
1.1
99.14
104.38
%
—
7
16
23
116
2.00
2.46
1.1
1.0
0.16
0.22
u/ml
0.12
12
38
14
57
2.47
2.45
1.3
1.1
—
—
—
0
0
47
296
1.61
2.44
1.4
1.3
—
—
—
0
0
935
8801
1.19
2.44
5.2
4.4
14.86
14.83
pmol/l
0.19
875
8060
528
4737
1.19
2.43
2.0
1.9
1.38
1.35
mmol/l
0.34
455
3985
52
338
1.56
2.38
3.7
3.4
10.16
1.73
index
0.56
26
176
143
1117
1.31
2.37
2.2
2.8
68.57
70.33
e9/l
0.26
102
829
75
531
1.44
2.29
2.0
2.3
3.82
3.74
g/l
0.21
66
487
75
532
1.43
2.27
2.0
2.3
7.11
7.47
g/l
1.36
66
487
75
532
1.43
2.27
2.0
2.3
4.36
4.24
g/l
0.26
66
487
26
143
1.83
2.20
1.4
1.4
—
—
—
0
0
1101
10571
1.20
2.08
7.5
6.5
40.24
39.57
mmol/mol
1.66
1036
9866
26
146
1.80
2.07
1.4
1.3
0.17
0.31
nmol/l
0.57
21
116
19
96
1.99
2.06
1.1
1.1
122.74
102.92
pmol/l
0.52
19
96
36
223
1.63
2.04
1.1
1.2
14.87
36.27
u/l
1.93
30
195
43
279
1.56
2.02
2.2
1.5
—
—
—
0
0
93
705
1.34
1.94
3.2
3.7
4.38
4.53
pmol/l
0.68
77
628
6
16
3.76
1.93
1.3
1.6
—
—
—
0
0
7
22
3.19
1.88
1.3
1.2
—
—
—
0
0
90
683
1.34
1.87
3.2
2.4
1.43
1.21
%
1.32
90
678
53
368
1.46
1.84
1.5
1.5
287.61
278.96
ug/g
0.10
33
222
55
386
1.44
1.81
1.4
1.3
—
—
—
0
0
7
23
3.05
1.80
1.1
1.3
—
—
—
0
0
27
161
1.69
1.79
1.9
1.6
—
—
—
0
0
49
338
1.47
1.77
3.7
4.0
3.88
3.90
mmol/l
0.13
49
332
123
983
1.28
1.77
4.0
3.1
179.10
213.11
ng/l
0.63
116
908
1199
11652
1.22
1.74
16.8
12.3
26.12
25.85
u/l
0.17
1172
11311
441
3987
1.16
1.73
4.6
3.3
33.10
33.50
u/l
0.05
420
3777
19
103
1.86
1.72
1.2
1.0
—
—
—
0
0
1180
11453
1.21
1.72
27.1
20.1
3.98
3.98
mmol/l
0.02
1158
11207
34
219
1.57
1.69
2.2
1.7
—
—
—
0
0
69
513
1.36
1.66
1.8
2.1
45.26
38.59
u/l
1.36
61
455
6
19
3.17
1.66
1.0
1.2
—
—
—
0
0
1124
10872
1.18
1.65
5.5
5.1
1.45
1.47
mmol/l
0.97
1044
10038
14
69
2.04
1.65
1.4
1.3
—
—
—
0
0
14
69
2.04
1.65
1.4
1.3
—
—
—
0
0
23
135
1.72
1.63
2.0
2.2
43.67
23.89
mg/l
—
9
53
20
113
1.78
1.61
1.1
1.1
—
—
—
0
0
46
321
1.45
1.59
1.9
1.6
—
—
—
0
0
45
313
1.45
1.58
1.4
1.3
—
—
—
0
0
1129
10934
1.18
1.58
5.6
5.2
4.53
4.61
mmol/l
1.99
1058
10173
6
20
3.01
1.58
1.3
1.0
—
—
—
0
0
18
99
1.83
1.57
1.1
1.2
1.49
0.66
u/ml
0.29
13
52
1146
11115
1.18
1.56
6.5
5.9
2.63
2.68
mmol/l
1.25
1070
10293
14
71
1.98
1.54
2.3
2.2
—
—
—
0
0
1176
11435
1.19
1.54
26.8
19.9
139.43
139.65
mmol/l
2.05
1156
11211
21
123
1.72
1.51
1.0
1.2
—
—
—
0
0
6
21
2.86
1.50
1.8
1.3
—
—
—
0
0
32
210
1.54
1.49
1.3
1.3
275.33
277.12
u/ml
0.01
24
118
14
72
1.95
1.49
1.7
1.5
—
—
—
0
0
61
805
0.75
1.44
1.9
1.8
3.31
3.50
mmol/l
0.72
36
593
46
328
1.42
1.44
1.9
1.6
—
—
—
0
0
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
13
66
1.98
1.43
1.6
1.9
13.63
19.41
nmol/l
2.36
13
60
13
66
1.98
1.43
3.5
3.5
0.77
0.88
index
0.33
13
66
98
787
1.26
1.40
7.9
8.2
24.53
24.99
mmol/l
0.81
98
781
38
264
1.45
1.37
1.6
1.5
—
—
—
0
0
18
104
1.74
1.37
1.6
1.6
—
—
—
0
0
85
673
1.28
1.36
3.2
2.4
0.64
0.62
%
0.31
85
668
88
1096
0.79
1.36
2.1
2.1
3.43
3.47
ratio
0.09
63
889
12
222
0.54
1.35
1.3
1.5
—
—
—
0
0
49
358
1.38
1.35
1.6
1.6
—
—
—
0
0
1074
10398
1.15
1.35
4.7
4.3
1.35
1.29
mmol/l
1.50
997
9524
25
159
1.58
1.35
1.7
1.6
—
—
—
0
0
14
75
1.88
1.34
1.7
1.5
—
—
—
0
0
10
47
2.14
1.34
1.1
1.1
—
—
—
0
0
155
1315
1.20
1.33
1.9
1.8
1.64
1.53
%
0.77
128
1126
11
54
2.05
1.33
1.0
1.0
—
—
—
0
0
43
310
1.40
1.29
2.2
2.1
124.39
129.07
g/l
0.62
28
246
69
536
1.30
1.29
1.0
1.1
—
—
—
0
0
19
114
1.68
1.28
2.7
2.6
—
—
—
0
0
19
114
1.68
1.28
2.3
1.6
—
—
—
0
0
115
952
1.23
1.27
3.9
2.7
60.62
65.93
ml/min/173m2
0.99
58
415
17
99
1.73
1.27
1.5
1.3
—
—
—
0
0
8
35
2.29
1.27
1.6
1.2
11.50
8.64
ug/l
—
8
35
35
244
1.45
1.26
1.4
1.4
—
—
—
0
0
301
2709
1.14
1.24
5.2
4.0
1.02
1.57
kg/l
0.50
200
1828
26
171
1.53
1.23
1.2
1.2
2.00
6.19
u/ml
1.37
11
69
154
1318
1.19
1.22
3.3
4.3
3.49
21.25
ug/l
2.04
125
1088
1103
10723
1.14
1.20
22.5
16.3
78.78
79.02
ml/min/173m2
0.14
1036
9987
35
248
1.42
1.17
1.9
1.3
—
—
—
0
0
35
248
1.42
1.17
1.9
1.3
—
—
—
0
0
39
282
1.39
1.17
1.8
3.1
31.45
34.13
umol/l
0.40
33
254
953
9191
1.12
1.16
29.7
20.9
13.88
13.72
%
2.86
945
9055
0
35
0.00
1.15
0.0
4.5
—
74.36
—
0
28
155
1337
1.18
1.13
8.3
7.0
—
—
—
0
0
66
521
1.28
1.12
1.3
1.3
—
—
—
0
0
53
407
1.31
1.10
1.7
1.6
11.69
12.73
u/ml
—
9
94
26
176
1.49
1.10
1.2
1.2
2.23
2.67
u/ml
0.20
13
51
1107
10785
1.13
1.09
5.8
5.2
6.05
5.98
mmol/l
0.99
1026
9847
1204
11801
1.16
1.06
30.0
22.0
80.54
78.21
umol/l
0.96
1189
11660
18
113
1.60
1.06
3.4
3.4
72.54
12.05
index
0.47
13
66
11
60
1.84
1.03
2.5
1.5
—
—
—
0
0
11
60
1.84
1.03
2.5
1.5
—
—
—
0
0
11
60
1.84
1.03
2.5
1.5
—
—
—
0
0
11
60
1.84
1.03
2.5
1.5
—
—
—
0
0
60
477
1.27
0.99
4.6
3.5
108.19
8344.39
u/ml
0.82
52
410
19
124
1.54
0.97
2.3
1.6
—
—
—
0
0
9
50
1.81
0.96
7.1
3.9
—
—
—
0
0
94
791
1.20
0.94
1.3
1.2
70.72
135.80
u/ml
1.82
31
311
6
27
2.23
0.93
1.0
1.2
—
—
—
0
0
39
295
1.33
0.93
1.5
1.6
—
—
—
0
0
28
201
1.40
0.91
1.5
1.5
—
—
—
0
0
37
279
1.34
0.91
1.4
1.4
—
—
—
0
0
21
143
1.48
0.90
1.1
1.4
42.26
26.71
u/l
0.85
15
118
14
87
1.62
0.87
1.7
1.5
—
—
—
0
0
12
192
0.62
0.86
1.4
1.5
0.96
0.96
ratio
—
5
122
12
192
0.62
0.86
1.4
1.5
0.83
1.21
ratio
—
5
122
12
192
0.62
0.86
1.4
1.5
0.97
1.14
ratio
—
5
122
279
2562
1.11
0.84
2.0
1.7
33603659.11
31906315.92
pmol/l
0.02
247
2125
8
45
1.78
0.84
1.0
1.2
2.86
5.17
umol/l
—
8
36
26
188
1.39
0.83
2.2
1.9
1.90
1.69
mmol/l
0.54
26
183
113
979
1.17
0.83
4.0
3.8
1.23
1.23
mmol/l
0.64
101
846
12
190
0.63
0.83
1.3
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
12
73
1.65
0.81
1.0
1.2
—
—
—
0
0
19
130
1.47
0.81
1.0
1.1
—
—
u/ml
—
0
0
8
47
1.71
0.80
1.3
1.0
—
—
—
0
0
488
4614
1.09
0.80
4.9
3.9
0.02
0.13
estimate
0.65
119
1081
21
147
1.44
0.80
1.6
1.4
280.85
278.68
mosm/kgh2o
0.17
13
108
78
658
1.20
0.79
3.6
3.7
51.21
47.65
%
0.63
78
645
12
74
1.63
0.78
1.0
1.2
—
—
—
0
0
7
124
0.56
0.78
4.3
2.1
13.00
13.23
%
—
7
124
7
38
1.85
0.73
1.1
1.2
123.57
106.06
%
—
7
32
7
38
1.85
0.73
1.0
1.2
—
—
—
0
0
5
25
2.00
0.72
2.2
1.7
1.16
1.21
mmol/l
—
5
25
5
25
2.00
0.72
1.0
1.2
—
—
—
0
0
36
282
1.28
0.71
1.9
2.0
3142.65
3856.39
u/l
0.13
14
109
32
247
1.30
0.71
1.5
1.4
—
—
—
0
0
10
61
1.64
0.68
1.1
1.1
—
—
—
0
0
54
451
1.21
0.63
3.1
2.9
24.99
24.88
mmol/l
0.10
54
445
59
499
1.19
0.61
1.4
1.3
21.42
29.47
iu/l
1.40
51
431
26
333
0.78
0.59
1.3
1.6
1265.64
975.39
mu/l
0.50
21
274
8
52
1.54
0.59
1.8
2.2
—
—
—
0
0
51
428
1.20
0.58
2.2
1.8
—
—
—
0
0
15
106
1.42
0.57
2.1
1.4
—
—
—
0
0
15
106
1.42
0.57
2.1
1.4
—
—
—
0
0
15
106
1.42
0.57
2.1
1.4
—
—
—
0
0
6
36
1.67
0.56
2.3
3.1
28.68
19.68
ug/l
—
6
30
5
89
0.56
0.56
1.0
1.5
82.20
83.89
umol/l
—
5
89
32
257
1.25
0.55
1.4
1.2
11.71
10.41
u/l
0.17
27
211
6
38
1.58
0.54
1.3
1.5
—
—
—
0
0
32
258
1.25
0.54
2.8
2.6
16.09
16.05
%
0.02
32
252
11
74
1.49
0.53
1.7
1.2
—
—
—
0
0
15
108
1.39
0.53
1.7
1.5
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
24
187
1.29
0.53
1.9
1.5
—
—
—
0
0
112
1014
1.11
0.49
1.8
2.3
0.41
0.46
e6/l
0.12
106
966
7
47
1.49
0.47
1.4
1.3
—
—
—
0
0
1214
12011
1.09
0.46
35.3
25.6
252.81
249.56
e9/l
0.94
1193
11782
153
1414
1.09
0.45
4.9
5.0
32.07
32.49
%
0.19
115
928
1214
12013
1.09
0.45
35.2
25.5
91.62
91.32
fl
1.43
1202
11881
1214
12016
1.09
0.44
35.3
25.5
4.42
4.45
e12/l
1.14
1194
11746
1214
12016
1.09
0.44
35.9
26.0
40.01
39.98
%
0.08
1203
11874
1214
12019
1.08
0.42
35.5
25.7
133.16
133.94
g/l
1.09
1203
11884
1214
12019
1.08
0.42
35.3
25.6
6.94
6.79
e9/l
1.23
1195
11742
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
0.53
—
0
15
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.6
1.4
—
—
—
0
0
29
242
1.20
0.39
1.3
1.7
0.89
0.87
nmol/l
0.04
23
203
53
468
1.14
0.37
2.6
1.9
—
—
—
0
0
49
431
1.14
0.36
2.1
1.8
—
—
—
0
0
32
272
1.18
0.36
1.6
1.2
3.84
3.74
mmol/l
0.22
32
256
6
43
1.40
0.35
1.3
1.7
—
—
—
0
0
11
82
1.34
0.34
2.3
1.7
—
—
—
0
0
21
173
1.22
0.33
1.1
1.1
—
1.04
—
0
7
16
128
1.25
0.32
1.4
1.6
23.03
33.79
ng/l
0.49
16
128
36
314
1.15
0.31
1.4
1.3
279.93
227.86
miu/ml
0.30
17
144
35
305
1.15
0.31
1.8
1.3
438.11
533.69
mg/l
1.18
35
290
21
175
1.20
0.30
5.4
5.9
366.63
356.26
umol/l
0.11
16
159
52
469
1.11
0.28
1.6
1.7
0.28
0.36
mg/l
0.50
24
221
36
317
1.14
0.28
2.5
2.0
2.73
4.10
iu/l
1.49
15
131
11
85
1.30
0.28
1.5
1.5
11.65
13.65
umol/l
0.48
11
78
9
72
1.25
0.25
2.6
2.2
—
—
—
0
0
42
378
1.11
0.25
1.5
1.4
—
—
—
0
0
133
1261
1.06
0.24
3.2
3.5
—
—
—
0
0
14
115
1.22
0.23
2.4
1.7
—
—
—
0
0
31
276
1.13
0.22
1.9
2.5
34.88
96.18
ug/min
1.48
14
155
22
252
0.87
0.22
5.4
3.9
25.28
28.78
mg/l
0.19
13
187
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
1952.33
1667.48
miu/ml
—
6
50
6
50
1.20
0.19
1.7
1.7
29.07
54.47
ug/l
—
6
50
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
58
622
0.93
0.19
4.0
3.4
1.02
1.02
ratio
0.24
48
579
39
357
1.10
0.18
1.1
1.1
1.51
1.57
g/l
0.67
39
357
28
252
1.11
0.18
2.9
3.6
10.30
1511.53
u/ml
0.88
23
239
80
845
0.94
0.17
2.3
2.3
12.65
12.77
nmol/l
0.05
73
754
7
63
1.11
0.17
1.4
1.4
—
—
—
0
0
8
69
1.16
0.16
1.5
1.4
—
—
—
0
0
8
69
1.16
0.16
1.5
1.4
—
—
—
0
0
8
70
1.14
0.16
1.0
1.1
—
—
—
0
0
28
254
1.10
0.16
5.7
4.9
5.05
5.05
kpa
0.00
28
249
9
82
1.10
0.15
1.2
1.5
1.94
2.99
ug/l
—
9
68
18
160
1.13
0.14
1.1
1.1
—
—
—
0
0
10
84
1.19
0.14
2.1
1.8
135.70
105.46
ng/l
—
10
84
15
132
1.14
0.13
1.6
1.6
—
—
—
0
0
9
110
0.82
0.13
2.1
1.6
—
—
—
0
0
289
2943
0.98
0.12
4.8
4.5
22.07
21.67
%
0.16
131
1440
55
523
1.05
0.11
2.1
1.8
—
—
—
0
0
5
44
1.14
0.10
1.0
1.3
—
—
—
0
0
5
45
1.11
0.09
1.0
1.0
108.80
95.92
%
—
5
37
5
47
1.06
0.09
1.2
1.2
6.60
8.06
mm/h
—
5
47
6
54
1.11
0.09
1.3
1.3
116.52
164.99
pmol/l
—
6
54
35
332
1.06
0.08
3.8
3.0
7.99
7.99
kpa
0.00
35
324
11
98
1.12
0.07
1.2
2.3
5.32
6.04
umol/l
—
5
72
364
3679
0.99
0.07
5.4
5.4
4.86
3.11
ug/l
0.46
323
3313
15
137
1.10
0.07
1.4
1.3
20060.33
82802.28
e6/l
—
6
76
9
84
1.07
0.07
1.2
1.1
187.67
242.42
mg/l
—
9
73
219
2162
1.02
0.06
3.6
3.2
0.63
0.79
ug/l
2.98
144
1423
17
159
1.07
0.05
1.1
1.0
—
—
—
0
0
10
110
0.91
0.05
1.0
1.1
—
—
—
0
0
26
272
0.96
0.04
2.1
1.5
262.19
847.56
e6/l
0.53
16
214
16
168
0.95
0.02
1.1
1.1
—
—
—
0
0
33
339
0.97
0.02
1.7
1.5
—
—
—
0
0
331
3296
1.01
0.02
4.1
3.4
2.16
0.29
estimate
0.41
116
1024
26
267
0.97
0.01
2.1
1.4
7.44
47.77
e6/l
0.94
16
203
171
1701
1.01
0.01
1.6
1.5
—
—
—
0
0
41
403
1.02
0.01
1.7
1.9
6.98
5.02
mg/l
0.18
32
304
14
146
0.96
0.00
1.0
1.1
2.52
2.01
eliau/ml
—
5
59
10
96
1.04
0.00
1.4
1.2
—
—
—
0
0
11
114
0.96
0.00
1.2
1.5
55.20
53.03
ug/l
0.13
11
114
16
156
1.03
0.00
1.4
1.4
2007.63
1602.09
e6/l
—
8
103
31
315
0.98
0.00
1.3
1.2
—
—
—
0
0
15
155
0.97
0.00
1.5
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.01
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
55.40
—
0
5
5
51
0.98
-0.00
1.8
1.4
—
—
—
0
0
5
49
1.02
-0.00
2.4
1.6
40.74
39.86
g/l
—
5
49
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
61
0.98
-0.00
1.2
1.2
—
—
—
0
0
6
64
0.94
-0.00
1.7
2.3
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.1
177.30
222.37
iu/ml
—
5
55
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.8
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.57
—
0
7
8
82
0.98
-0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_OTHACUSKINSUN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHACUSKINSUN | 0.926 [0.79, 1.09] | 0.361 |
| Birth year | 0.998 [0.99, 1.01] | 0.614 |
During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 2255 females with L12_OTHACUSKINSUN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHACUSKINSUN | 1.147 [0.96, 1.37] | 0.129 |
| Birth year | 0.99 [0.98, 1.0] | 0.046 |
During the follow-up period (1.1.1998 — 31.12.2019), 282 out of 1251 males with L12_OTHACUSKINSUN died.
Mortality risk
Mortality risk for people of age
years, who have L12_OTHACUSKINSUN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.216% |
| 5 | 0.486% | 1.37% |
| 10 | 1.451% | 3.59% |
| 15 | 2.824% | 6.989% |
| 20 | 5.077% | 12.099% |
Relationships between endpoints
↥Index endpoint: L12_OTHACUSKINSUN – Other acute skin changes due to ultraviolet radiation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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