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R14

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Other parasitologically confirmed or unspecified malaria, including avohilmo

Endpoint Browser PheWeb

AB1_MALARIA_NOS_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — B53, B54
  • Hospital discharge: ICD-10 — B53, B54
  • Hospital discharge: ICD-9 — 08[4]
  • Hospital discharge: ICD-8 — 08[4]
  • Hospital discharge: excluded ICD-9 — 084[0-1]
  • Hospital discharge: excluded ICD-8 — 084[0-1]
  • Cause of death: ICD-10 — B53, B54
  • Cause of death: ICD-9 — 08[4]
  • Cause of death: ICD-8 — 08[4]
  • Cause of death: excluded ICD-9 — 084[0-1]
  • Cause of death: excluded ICD-8 — 084[0-1]

3 out of 7 registries used, show all original rules.

124

4. Check minimum number of events

None

124

5. Include endpoints

None

124

6. Filter based on genotype QC (FinnGen only)

102

Control definitions (FinnGen only)

Control exclude
AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF13

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 102 54 48
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 38.85 35.91 42.15

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
117
Matched controls
1170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B54
ICD-10 Finland
Unspecified malaria
+∞
98.2
80
*
B50.9
ICD-10 Finland
Plasmodium falciparum malaria, unspecified
+∞
10.6
10
*
0846X
ICD-9 Finland
Malaria, unspecified
+∞
7.4
7
*
R50.9
ICD-10 Finland
Fever, unspecified
3.3
7.1
33
125
J01MA02
ATC
ciprofloxacin; systemic
2.8
6.9
56
289
08499
ICD-8 Finland
Malaria, Unspecified forms
+∞
6.3
6
*
B53.0
ICD-10 Finland
Plasmodium ovale malaria
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
275
2.70
6.35
2.9
3.2
0.21
0.33
e6/l
0.48
38
202
58
324
2.57
5.87
3.1
3.4
7.45
35.82
e6/l
2.29
44
250
62
375
2.39
5.08
4.3
4.3
15.56
72.04
e6/l
0.88
44
262
31
163
2.23
3.31
2.8
3.2
2.33
2.17
e6/l
0.04
13
79
6
12
5.20
2.43
2.8
1.2
—
—
—
0
0
6
12
5.20
2.43
2.8
1.2
—
—
—
0
0
6
12
5.20
2.43
2.8
1.2
—
—
—
0
0
6
12
5.20
2.43
2.8
1.2
—
—
—
0
0
63
463
1.78
2.42
11.5
11.4
0.00
0.00
e9/l
-0.00
48
373
5
8
6.47
2.39
1.8
1.3
—
—
—
0
0
40
260
1.82
2.30
3.8
4.9
—
—
—
0
0
52
376
1.69
2.02
2.7
2.0
—
—
—
0
0
20
107
2.05
2.01
1.8
2.4
31.20
28.42
u/l
0.27
15
89
47
335
1.67
1.90
8.9
6.2
—
—
—
0
0
25
149
1.86
1.86
2.2
2.4
—
—
—
0
0
5
12
4.30
1.84
1.6
3.3
—
—
—
0
0
41
284
1.68
1.84
1.8
2.3
—
—
—
0
0
6
18
3.45
1.77
1.8
3.1
7.37
7.43
ph
—
6
18
16
85
2.02
1.64
1.4
1.3
—
—
—
0
0
19
111
1.85
1.50
1.5
1.2
—
—
—
0
0
7
28
2.59
1.47
1.3
1.4
—
—
—
0
0
14
75
1.98
1.41
19.3
10.7
1.72
1.56
mmol/l
0.10
14
75
5
18
2.85
1.30
12.8
3.7
43.82
16.81
u/ml
—
5
18
41
312
1.48
1.17
1.8
1.5
—
—
—
0
0
18
113
1.70
1.14
2.5
1.8
—
—
—
0
0
24
163
1.59
1.13
1.9
2.1
—
—
—
0
0
42
325
1.46
1.09
2.9
2.4
—
—
—
0
0
53
431
1.42
1.05
1.8
1.9
1.31
1.40
mmol/l
0.26
46
368
7
34
2.12
1.05
1.1
1.1
—
—
—
0
0
38
292
1.45
1.02
5.1
4.5
7.40
7.39
ph
0.22
27
207
13
78
1.75
0.96
21.2
11.7
—
—
—
0
0
69
595
1.39
0.94
11.7
9.9
3.67
4.03
e9/l
0.81
61
516
12
71
1.77
0.93
9.3
10.2
6.55
8.79
mmol/l
1.27
12
71
8
43
1.92
0.89
2.0
1.7
—
—
—
0
0
58
491
1.36
0.86
8.3
6.3
0.74
0.67
%
0.44
53
460
8
45
1.83
0.86
1.4
1.6
—
—
—
0
0
14
89
1.65
0.86
3.3
2.7
0.21
0.22
g/l
0.29
14
82
51
424
1.36
0.85
7.8
5.2
35.10
36.51
g/l
0.96
46
405
58
492
1.35
0.85
8.3
6.2
2.63
2.76
%
0.20
53
466
18
123
1.55
0.84
1.4
1.6
—
—
—
0
0
58
493
1.35
0.83
8.4
6.3
9.12
8.58
%
0.62
53
468
26
194
1.44
0.81
3.0
3.2
1133.94
260.98
ng/l
0.51
16
139
54
459
1.33
0.76
10.5
9.5
1.21
1.22
mmol/l
0.38
49
402
9
55
1.69
0.75
27.4
9.4
25.84
24.76
mmol/l
—
9
55
5
24
2.13
0.75
3.4
3.4
54.80
62.37
%
—
5
24
10
60
1.73
0.74
1.9
1.2
—
—
—
0
0
9
56
1.66
0.74
31.9
14.4
95.06
93.99
%
—
9
56
7
39
1.84
0.74
3.4
2.2
—
—
—
0
0
39
318
1.34
0.72
8.5
5.9
—
—
—
0
0
61
531
1.31
0.71
7.9
6.3
0.53
0.56
e9/l
0.58
50
462
62
543
1.30
0.68
7.9
6.4
1.81
1.82
e9/l
0.07
51
490
61
534
1.30
0.67
8.0
6.3
0.04
0.04
e9/l
0.15
50
465
20
148
1.42
0.65
2.8
2.2
96.93
108.72
ug/g
0.15
15
120
5
30
1.70
0.62
1.6
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.0
—
1.35
—
0
8
8
52
1.58
0.61
2.6
4.3
25.30
24.36
mmol/l
—
8
52
10
64
1.62
0.61
1.2
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
1.07
—
0
8
0
21
0.00
0.60
0.0
1.0
—
12.78
—
0
14
0
21
0.00
0.60
0.0
2.0
—
5.36
—
0
16
24
302
0.74
0.60
4.8
3.4
215.98
69.57
mg/l
0.54
15
200
8
54
1.52
0.58
1.4
1.4
—
—
—
0
0
62
552
1.26
0.57
8.4
6.5
0.17
0.19
e9/l
0.30
54
491
25
309
0.76
0.55
6.6
3.9
34.99
10.80
mg/mmol
0.42
14
199
15
109
1.43
0.54
1.6
1.7
—
—
—
0
0
53
466
1.25
0.53
4.0
2.9
—
—
estimate
—
0
0
17
127
1.40
0.53
8.2
7.9
1.02
1.02
mmol/l
0.03
17
119
22
172
1.34
0.53
5.8
3.6
0.84
0.81
mmol/l
0.61
22
164
104
995
1.41
0.49
4.1
4.8
4.74
4.64
mmol/l
0.47
98
940
10
141
0.68
0.48
1.7
1.4
—
—
—
0
0
36
307
1.25
0.46
3.2
3.3
—
0.29
—
0
7
16
123
1.35
0.43
2.1
1.8
—
—
—
0
0
5
32
1.59
0.43
1.0
1.3
—
—
—
0
0
12
159
0.73
0.42
1.3
1.5
—
—
—
0
0
21
256
0.78
0.41
1.6
1.4
3.22
2.46
g/l
0.54
15
160
0
15
0.00
0.41
0.0
1.5
—
1.75
—
0
15
0
15
0.00
0.41
0.0
2.2
—
10.47
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
5.96
—
0
7
104
1001
1.35
0.40
4.6
5.4
2.88
2.73
mmol/l
0.96
99
942
0
18
0.00
0.40
0.0
1.0
—
1.59
—
0
10
28
236
1.25
0.40
2.4
2.0
3.45
2.67
mg/l
0.57
23
207
12
89
1.39
0.39
2.3
1.9
12.24
10.06
g/l
0.51
12
84
16
125
1.32
0.39
22.4
8.5
105.06
104.06
mmol/l
0.51
16
125
34
294
1.22
0.38
3.3
3.5
0.00
0.03
estimate
0.74
11
99
9
69
1.33
0.38
1.3
1.3
—
—
—
0
0
27
228
1.24
0.38
1.4
1.8
—
—
—
0
0
108
1046
1.42
0.37
13.4
12.6
—
—
—
0
0
47
423
1.19
0.35
12.1
10.2
1.14
1.16
inr
0.11
42
353
6
44
1.38
0.35
3.8
2.0
0.68
0.63
%
—
6
44
6
44
1.38
0.35
3.8
2.1
1.67
1.13
%
—
6
44
104
1005
1.31
0.35
19.2
15.0
32.04
22.97
mg/l
1.36
86
816
103
995
1.29
0.33
4.0
4.7
1.43
1.43
mmol/l
0.02
96
933
32
362
0.84
0.31
3.4
3.4
21.14
36.23
ng/l
0.96
22
238
20
167
1.24
0.31
2.0
1.8
—
—
—
0
0
8
63
1.29
0.28
1.4
1.3
—
—
—
0
0
59
549
1.15
0.28
3.9
3.8
0.00
0.00
estimate
-0.00
11
106
9
72
1.27
0.26
1.3
1.3
—
—
—
0
0
9
73
1.25
0.26
1.3
1.3
—
—
—
0
0
9
73
1.25
0.26
1.1
1.3
—
—
—
0
0
28
315
0.85
0.25
3.9
3.0
0.00
0.00
estimate
-0.00
12
87
20
231
0.84
0.24
2.0
1.7
0.61
1.35
mg/l
1.64
13
180
5
40
1.26
0.22
1.4
1.5
—
—
—
0
0
5
40
1.26
0.22
1.4
1.5
1.30
1.39
mm
—
5
29
34
308
1.15
0.22
5.5
4.7
2.36
1.71
ug/l
1.19
29
281
78
746
1.14
0.22
3.8
4.4
14.15
14.72
pmol/l
1.28
73
689
31
342
0.87
0.22
3.9
3.2
7.45
8.41
mmol/l
0.70
25
300
5
42
1.20
0.22
1.8
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
90.33
—
0
12
0
12
0.00
0.21
0.0
2.3
—
10.53
—
0
12
47
437
1.13
0.21
3.8
3.4
6.17
6.19
ph
0.03
20
247
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
10
122
0.80
0.20
1.4
1.4
—
—
—
0
0
57
538
1.12
0.19
4.0
3.7
0.00
0.00
estimate
-0.00
12
109
13
109
1.22
0.19
1.5
1.4
—
—
—
0
0
28
253
1.14
0.19
4.4
4.7
—
—
—
0
0
12
142
0.83
0.18
1.2
1.3
—
—
—
0
0
38
408
0.90
0.17
3.7
3.5
0.00
0.03
estimate
0.49
12
91
8
69
1.17
0.17
1.0
1.1
—
—
—
0
0
11
93
1.20
0.15
4.6
4.6
0.80
0.69
%
—
5
29
57
544
1.09
0.14
4.0
3.7
0.00
0.00
estimate
-0.00
12
111
9
105
0.85
0.13
1.3
1.2
—
—
—
0
0
41
391
1.07
0.10
1.9
2.1
89.82
97.46
pmol/l
0.74
19
199
5
47
1.07
0.09
9.0
15.4
—
—
—
0
0
29
273
1.08
0.09
2.9
3.1
—
—
—
0
0
10
88
1.15
0.08
4.5
4.5
7.37
7.38
ph
—
5
53
8
74
1.09
0.07
6.8
3.4
—
—
—
0
0
25
238
1.06
0.05
2.4
3.6
1.02
1.02
kg/l
0.27
16
163
48
467
1.05
0.05
2.7
2.8
—
—
—
0
0
11
102
1.09
0.03
26.4
14.6
5.32
5.05
kpa
0.48
11
97
11
102
1.09
0.03
26.4
14.7
7.43
7.41
ph
—
5
57
11
102
1.09
0.03
26.4
14.6
12.13
13.27
kpa
0.49
11
97
95
947
1.02
0.00
3.3
4.1
1.24
1.32
mmol/l
0.53
88
883
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
12.22
—
0
5
0
9
0.00
0.00
0.0
1.1
—
230.11
—
0
9
0
5
0.00
0.00
0.0
2.2
—
16.60
—
0
5
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
1980.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
2090.29
—
0
7
5
53
0.94
-0.00
1.6
3.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.2
—
896.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
4.4
4.6
122.86
80.92
ng/l
—
7
68
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
11.7
—
1377.17
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
7.18
—
0
6
0
8
0.00
-0.00
0.0
6.4
—
0.60
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
0.67
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: AB1_MALARIA_NOS_WIDE – Other parasitologically confirmed or unspecified malaria, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).