Mandibular prognathia AND surgery (LeFortI or BSSO)

K11_MN_PROGN_AND_SURGRT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • OPER_LEFORT1_BSSRO
1838

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K07.11
  • Cause of death: ICD-10 K07.11

2 out of 7 registries used, show all original rules.

205

4. Check minimum number of events

None

205

5. Include endpoints

None

205

6. Filter based on genotype QC (FinnGen only)

179

Control definitions (FinnGen only)

Control exclude
K11_MN_PROGN_AND_SURGRT_INCLAVO

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1251 708 535
Only index persons 1235 701 534
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 28.06 27.97 28.18
Only index persons 28.04 27.92 28.20

-FinnGen-

Key figures

All Female Male
Number of individuals 179 114 65
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 34.11 35.14 32.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
193
Matched controls
1930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
+∞
279.4
193
*
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
169.0
235.0
121
19
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
183.5
213.7
107
13
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
149.1
212.7
110
17
SJC10
NOMESCO Finland
Orthodontic band in one tooth
195.5
206.0
102
11
SBB10
NOMESCO Finland
Dental impressions
58.1
187.7
140
84
EEC05
NOMESCO Finland
Le Fort I osteotomy
6244.0
186.8
149
*
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
116.1
184.6
98
17
EB1MA
NOMESCO Finland
Cephalometry with X-ray
103.8
180.9
98
19
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
127.3
178.7
93
14
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
68.6
173.7
105
33
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
62.8
169.3
105
36
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
113.2
152.6
80
12
K07.14
ICD-10 Finland
Retrognaty, maxillary
1226.2
126.7
110
*
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
85.0
123.0
67
12
K07.13
ICD-10 Finland
Retrognaty, mandibular
93.0
117.8
63
10
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
530.6
113.0
102
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
60.4
106.6
62
15
SAA04
NOMESCO Finland
Special examination of mouth
24.5
93.3
77
51
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
203.9
91.5
89
8
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
170.3
86.8
86
9
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
37.1
79.1
52
19
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
31.1
73.1
51
22
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
20.3
72.5
63
45
SXC05
NOMESCO Finland
Other oral or dental procedure
15.4
65.4
68
66
K07.10
ICD-10 Finland
Asymmetry of jaw
381.6
57.5
55
*
K07.24
ICD-10 Finland
Open bite
86.8
51.6
56
9
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
23.9
48.8
37
19
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
511.5
42.9
41
*
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
+∞
41.1
38
*
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
7.1
39.0
84
190
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
54.7
36.8
43
10
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
59.1
36.5
42
9
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
7.7
33.2
56
97
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
+∞
31.1
29
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
183.5
30.6
31
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
+∞
30.0
28
*
WZC00
NOMESCO Finland
Treatment plan or consultation
5.3
28.5
124
492
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
32.4
28.3
37
14
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
298.6
26.4
26
*
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
+∞
25.6
24
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
8.1
25.2
38
57
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
9.3
25.1
33
42
SAA03
NOMESCO Finland
Extended examination of mouth
4.9
24.0
138
652
K07.60
ICD-10 Finland
Snapping jaw
6.4
22.2
42
80
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
86.2
21.2
23
*
Z3229
NOMESCO Finland
Other healthcare associate professional
6.8
20.1
35
61
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
9.4
19.7
25
30
EBB10
NOMESCO Finland
Insertion of dental implant
38.8
19.4
24
7
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
78.0
19.1
21
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
111.0
18.9
20
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.0
18.0
45
110
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
27.2
17.8
24
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.8
17.4
127
654
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
+∞
16.9
16
*
SXC03
NOMESCO Finland
Other oral or dental procedure
65.7
16.1
18
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
+∞
15.8
15
*
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
+∞
15.8
15
*
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.6
15.6
33
69
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.7
14.6
38
95
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
29.9
14.6
19
7
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
28.1
13.6
18
7
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
28.1
13.6
18
7
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
12.2
66
271
ZXA10
NOMESCO Finland
Bilateral
3.5
11.8
48
165
ZXE30
NOMESCO Finland
More than five and less than seven hours
9.0
11.5
24
30
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
18.5
11.4
17
10
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
13.9
11.4
19
15
K07.4
ICD-10 Finland
Malocclusion, unspecified
15.1
11.2
18
13
K00.00
ICD-10 Finland
Hypodontia
16.8
11.1
17
11
EB1WA, ,
NOMESCO Finland
30.0
10.9
14
5
EBB15
NOMESCO Finland
Insertion of dental implant abutment
34.6
10.5
13
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
42.4
10.1
12
*
SPC20
NOMESCO Finland
Implant borne crown
42.4
10.1
12
*
K07.23
ICD-10 Finland
Deep bite
10.4
10.0
19
20
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
18.7
9.6
14
8
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
11.5
9.5
17
16
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
11.5
9.5
17
16
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
11.5
9.5
17
16
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
+∞
9.4
9
*
EBA10
NOMESCO Finland
Operative extraction of tooth
2.7
8.2
55
248
J01CE02
ATC
phenoxymethylpenicillin; oral
2.9
8.1
157
1157
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.3
7.5
17
25
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
83.2
7.5
8
*
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
11.5
7.4
13
12
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.6
7.4
18
42
EEC02
NOMESCO Finland
Rapid expansion of maxilla
+∞
7.3
7
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.4
7.1
64
330
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
4.3
7.1
19
48
SPC10
NOMESCO Finland
Standard dental crown
11.5
6.9
12
11
M01AE03
ATC
ketoprofen; systemic, rectal
2.3
6.8
71
390
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
23.5
6.7
9
*
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
10.6
6.6
12
12
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
6.5
37
152
WX720
NOMESCO Finland
Own respiration
4.3
6.5
17
42
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
72.1
6.5
7
*
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
+∞
6.3
6
*
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
6.3
6
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
332
1.82
3.22
1.7
1.6
—
—
—
0
0
73
505
1.72
3.15
3.1
2.7
0.00
0.00
estimate
-0.00
13
140
7
14
5.14
2.75
1.0
1.0
—
—
—
0
0
151
1325
1.64
2.13
4.5
4.5
14.57
14.56
pmol/l
0.00
141
1243
7
20
3.59
2.07
3.0
2.2
7.01
6.69
mmol/l
—
7
20
70
886
0.67
1.89
4.5
6.1
0.04
0.04
e9/l
0.02
63
764
83
658
1.46
1.78
3.5
3.1
0.00
0.01
estimate
0.50
13
142
186
1769
2.42
1.77
11.7
10.4
—
—
—
0
0
0
48
0.00
1.72
0.0
1.3
—
—
—
0
0
26
402
0.59
1.71
2.5
2.8
—
—
estimate
—
0
0
71
884
0.69
1.70
4.5
6.1
0.49
0.52
e9/l
1.17
65
764
37
249
1.60
1.69
1.6
1.6
475.70
52000473.08
pmol/l
0.50
30
225
185
1758
2.26
1.68
11.9
14.4
72.76
71.49
umol/l
0.39
185
1734
7
26
2.75
1.59
3.1
2.2
1.26
1.25
mmol/l
—
7
26
107
903
1.42
1.58
3.5
3.4
0.00
0.00
estimate
-0.00
17
163
168
1548
1.66
1.56
5.2
5.3
1.68
1.76
mu/l
0.68
158
1471
106
896
1.41
1.53
3.5
3.3
88.05
0.00
estimate
0.48
19
173
75
910
0.71
1.48
4.4
6.1
1.80
2.02
e9/l
0.98
70
810
34
476
0.65
1.44
2.9
2.9
28.84
37.60
e6/l
0.23
28
353
54
409
1.44
1.43
3.5
3.1
1.02
1.02
kg/l
0.17
36
261
7
29
2.47
1.40
3.3
2.3
7.41
7.41
ph
—
7
29
28
406
0.64
1.39
3.2
2.8
0.90
0.26
e6/l
0.39
21
289
92
768
1.38
1.39
3.2
2.6
—
—
—
0
0
9
41
2.25
1.39
2.2
1.5
10.32
20.57
u/l
—
9
35
15
83
1.88
1.35
1.3
1.3
—
—
—
0
0
6
24
2.55
1.31
6.8
2.9
—
—
—
0
0
65
518
1.38
1.29
1.8
2.3
—
—
—
0
0
94
798
1.35
1.24
2.6
2.8
—
—
estimate
—
0
0
45
578
0.71
1.19
3.0
3.6
56.78
60.99
e6/l
0.04
28
369
60
478
1.37
1.18
2.3
2.6
54.33
63.98
u/l
0.53
60
452
63
766
0.74
1.18
10.8
8.9
0.00
0.00
e9/l
-0.00
53
611
80
668
1.34
1.16
4.7
7.4
1.23
1.21
mmol/l
1.18
73
592
165
1541
1.49
1.13
4.2
4.1
5.65
5.75
mmol/l
0.51
154
1448
28
195
1.51
1.12
1.1
1.2
—
—
—
0
0
28
195
1.51
1.12
1.2
1.8
—
—
—
0
0
161
1499
1.45
1.10
5.4
5.0
37.64
37.93
mmol/mol
0.20
155
1440
5
109
0.44
1.04
2.2
1.3
—
—
—
0
0
7
133
0.51
1.03
3.1
2.9
0.19
0.23
g/l
—
7
124
61
497
1.33
1.03
2.3
2.7
77.59
31.08
ng/l
0.38
28
265
9
48
1.92
1.02
8.0
8.7
—
—
—
0
0
101
885
1.30
1.00
3.5
3.3
0.00
0.00
estimate
-0.00
18
172
15
230
0.62
0.96
3.2
2.8
3.58
3.38
e6/l
—
6
106
85
969
0.78
0.92
6.1
9.7
3.77
3.90
e9/l
0.23
78
835
10
56
1.83
0.89
1.0
1.1
—
—
—
0
0
10
56
1.83
0.89
1.0
1.1
—
—
—
0
0
19
129
1.52
0.87
2.2
2.0
6.12
6.18
ph
0.08
13
85
100
886
1.27
0.87
3.2
3.1
80.89
93.28
ug/l
0.49
93
845
173
1652
1.46
0.82
4.4
4.3
1.47
1.46
mmol/l
0.07
166
1578
100
891
1.25
0.81
3.6
5.2
6.43
6.42
mmol/l
0.02
90
809
84
735
1.25
0.79
3.6
3.1
6.08
6.20
ph
0.52
50
404
174
1669
1.43
0.74
4.8
4.7
2.77
2.82
mmol/l
0.31
168
1592
31
241
1.34
0.72
2.2
2.0
—
—
—
0
0
173
1660
1.41
0.70
4.5
4.3
4.71
4.73
mmol/l
0.08
165
1591
5
28
1.81
0.66
3.2
1.6
10.88
4.96
pmol/l
—
5
28
65
564
1.23
0.65
6.6
7.3
1.09
1.10
inr
0.14
52
461
13
186
0.68
0.63
2.7
2.4
0.52
0.68
ug/l
—
6
92
5
30
1.68
0.62
1.2
1.4
—
—
—
0
0
25
193
1.34
0.61
1.3
1.5
—
—
—
0
0
16
114
1.44
0.61
1.3
1.4
160.28
296.63
miu/ml
—
10
63
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
47
551
0.81
0.60
4.6
5.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
25
315
0.76
0.58
1.9
2.4
10.07
7.38
e6/l
0.26
25
282
69
611
1.20
0.55
1.8
1.6
—
—
—
0
0
9
61
1.50
0.54
3.9
12.4
1.47
1.62
%
—
9
56
162
1555
1.26
0.52
3.8
3.7
1.27
1.27
mmol/l
0.02
157
1471
11
156
0.69
0.52
1.3
1.3
148.26
135.65
u/ml
—
5
67
37
438
0.81
0.52
3.8
2.4
—
—
—
0
0
17
127
1.37
0.51
3.2
1.5
—
—
—
0
0
7
109
0.63
0.50
3.0
10.5
—
—
—
0
0
43
369
1.21
0.47
1.5
1.7
0.67
0.96
mg/l
0.70
34
275
17
129
1.35
0.47
3.4
3.4
—
—
—
0
0
15
112
1.37
0.46
1.1
1.2
—
—
—
0
0
42
484
0.83
0.45
2.3
5.7
—
—
—
0
0
9
126
0.70
0.45
1.2
1.1
—
—
—
0
0
38
324
1.22
0.45
1.3
1.3
1.87
5.31
u/ml
1.33
19
138
19
149
1.31
0.44
2.7
1.6
—
—
—
0
0
26
213
1.26
0.43
1.5
1.8
3.45
3.48
mmol/l
0.04
15
161
11
79
1.42
0.41
1.6
1.3
6.90
9.62
u/l
0.87
11
67
0
15
0.00
0.41
0.0
1.7
—
617.56
—
0
9
0
17
0.00
0.41
0.0
1.9
—
0.58
—
0
17
0
18
0.00
0.40
0.0
16.1
—
811.28
—
0
18
10
71
1.43
0.40
1.0
1.1
—
—
—
0
0
57
632
0.86
0.39
1.9
1.8
110.68
97.82
pmol/l
0.98
36
325
0
19
0.00
0.39
0.0
20.4
—
1605.79
—
0
19
5
36
1.40
0.38
1.6
1.4
217.60
306.20
mu/l
—
5
30
20
162
1.26
0.37
3.0
1.6
—
—
—
0
0
173
1687
1.25
0.36
10.7
12.2
19.01
20.45
mg/l
0.32
141
1320
59
649
0.87
0.36
2.1
1.8
—
—
—
0
0
20
163
1.25
0.36
3.0
1.6
—
—
—
0
0
20
164
1.24
0.34
2.7
1.6
—
—
—
0
0
37
420
0.85
0.34
4.7
4.2
1.25
11.19
mg/mmol
3.29
24
268
6
45
1.34
0.34
1.0
1.3
3.82
3.48
mmol/l
—
6
45
37
419
0.86
0.33
3.6
3.6
11.99
73.03
mg/l
3.22
25
273
30
345
0.85
0.32
5.0
4.2
—
—
—
0
0
22
184
1.22
0.32
1.2
1.5
—
—
—
0
0
7
99
0.70
0.31
1.0
1.1
—
—
—
0
0
20
166
1.23
0.31
2.8
1.5
—
—
—
0
0
17
139
1.24
0.30
2.5
2.4
465.66
9211.48
u/l
—
5
65
7
57
1.24
0.29
2.0
1.2
—
—
—
0
0
8
63
1.28
0.28
2.1
2.0
—
—
—
0
0
40
443
0.88
0.27
3.8
4.6
—
—
—
0
0
56
606
0.89
0.26
3.0
2.2
—
—
—
0
0
75
706
1.10
0.23
2.0
1.9
1.29
1.38
mmol/l
0.45
65
629
5
38
1.32
0.23
2.6
1.7
26.12
23.73
mmol/l
—
5
38
24
211
1.16
0.22
1.6
1.6
—
—
—
0
0
17
198
0.84
0.22
1.1
1.2
—
—
—
0
0
35
317
1.13
0.21
1.7
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
1.00
—
0
11
0
10
0.00
0.21
0.0
1.2
—
7.74
—
0
10
0
10
0.00
0.21
0.0
1.0
—
112.21
—
0
10
0
12
0.00
0.21
0.0
1.0
—
1575.17
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
29
260
1.14
0.20
1.9
3.5
9.44
631.15
ng/l
0.87
16
167
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
30
272
1.12
0.18
1.4
1.3
—
—
—
0
0
5
67
0.74
0.17
7.8
1.8
—
—
—
0
0
43
460
0.92
0.16
1.5
1.4
1.96
2.24
g/l
0.47
30
294
19
213
0.88
0.15
1.3
3.0
4.09
4.15
e9/l
0.04
19
195
9
78
1.16
0.15
1.7
1.3
—
—
—
0
0
44
412
1.09
0.15
3.2
2.8
—
—
—
0
0
7
86
0.81
0.15
1.1
2.0
2.80
10.25
ug/l
—
7
81
8
99
0.80
0.14
1.9
2.0
—
—
—
0
0
9
107
0.83
0.13
3.1
2.2
0.13
0.14
e6/l
—
9
100
9
109
0.82
0.13
1.4
1.6
—
—
—
0
0
62
593
1.07
0.13
3.3
6.7
1.23
1.21
mmol/l
0.65
57
553
54
516
1.06
0.11
1.3
1.4
0.71
1.97
u/ml
1.12
16
143
39
412
0.93
0.11
3.6
3.7
7.40
7.40
ph
0.43
29
282
20
183
1.10
0.10
1.9
1.6
—
—
—
0
0
17
187
0.90
0.10
1.1
1.2
—
—
—
0
0
5
45
1.11
0.10
1.0
1.5
49.80
230.49
e6/l
—
5
35
5
48
1.04
0.09
1.6
2.1
—
—
—
0
0
11
97
1.14
0.09
1.0
1.0
—
0.64
—
0
7
6
56
1.07
0.09
2.3
2.1
—
—
—
0
0
12
107
1.13
0.08
4.9
2.1
—
—
—
0
0
6
71
0.84
0.08
3.3
11.0
—
—
—
0
0
8
73
1.10
0.07
2.4
1.5
—
—
—
0
0
10
111
0.90
0.06
1.7
1.6
—
—
—
0
0
37
358
1.04
0.04
1.5
1.4
10.18
25.84
iu/ml
2.04
14
97
11
101
1.09
0.04
1.0
1.0
1.45
1.55
g/l
0.88
11
101
12
111
1.09
0.04
3.9
5.6
0.00
0.11
%
—
5
27
50
488
1.03
0.04
2.1
1.8
—
—
—
0
0
11
119
0.92
0.04
1.3
1.2
—
—
—
0
0
13
121
1.08
0.04
1.8
4.1
4.50
4.77
pmol/l
0.31
13
107
13
121
1.08
0.04
3.8
5.5
0.00
1.14
%
—
6
37
42
410
1.03
0.03
2.5
1.8
—
—
—
0
0
11
103
1.07
0.02
1.0
1.0
0.75
0.90
g/l
2.21
11
103
22
213
1.04
0.01
1.8
2.3
—
—
—
0
0
47
463
1.02
0.01
3.1
3.3
0.00
0.01
estimate
0.50
16
166
16
166
0.96
0.00
2.8
8.2
105.44
104.93
mmol/l
0.32
16
166
9
96
0.93
0.00
2.2
3.9
68.11
69.82
ng/l
—
9
87
6
60
1.00
0.00
1.5
2.1
0.58
0.61
%
—
6
60
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.0
—
6.89
—
0
7
5
58
0.86
-0.00
1.8
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
0.61
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
62
0.97
-0.00
1.5
2.1
0.75
1.65
%
—
6
62
0
5
0.00
-0.00
0.0
1.0
—
8.80
—
0
5
7
76
0.92
-0.00
3.4
8.8
24.87
24.97
mmol/l
—
7
76
6
59
1.02
-0.00
2.7
2.6
3.85
4.43
umol/l
—
6
40
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
0.00
—
0
9
12
120
1.00
-0.00
1.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
17.42
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.7
—
18.25
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
5.84
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
48
480
1.00
-0.00
1.5
2.9
2.36
2.35
mmol/l
0.07
42
447
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_MN_PROGN_AND_SURGRT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MN_PROGN_AND_SURGRT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_MN_PROGN_AND_SURGRT – Mandibular prognathia AND surgery (LeFortI or BSSO)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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