alcoholic cardiomyopathy: Disease of CARDIAC MUSCLE resulting from chronic excessive alcohol consumption. Myocardial damage can be caused by: (1) a toxic effect of alcohol; (2) malnutrition in alcoholics such as THIAMINE DEFICIENCY; or (3) toxic effect of additives in alcoholic beverages such as COBALT. This disease is usually manifested by DYSPNEA and palpitations with CARDIOMEGALY and congestive heart failure (HEART FAILURE).
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
231 |
4. Check minimum number of eventsNone |
231 |
5. Include endpointsNone |
231 |
6. Filter based on genotype QC (FinnGen only) |
204 |
Control definitions (FinnGen only)
- Control exclude
- I9_CARDMYO
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I42
- Name in latin
- Cardiomyopathia alcoholica
Similar endpoints
↥List of similar endpoints to
Alcoholic cardiomyopathy
based on the number of shared cases.
Similar with more cases:
- Cardiomyopathy
- Alcohol use disorder, Swedish definition
- Alcohol related diseases, tilastokeskus definition
- Alcohol related diseases and deaths, all endpoints
- Other heart diseases, wide
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5527 | 579 | 4785 |
| Only index persons | 1818 | 218 | 1600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.02 | 0.13 |
| Only index persons | 0.05 | 0.01 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 54.66 | 56.03 | 54.42 |
| Only index persons | 58.18 | 59.42 | 58.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 204 | 19 | 185 |
| Unadjusted period prevalence (%) | 0.08 | 0.01 | 0.08 |
| Median age at first event (years) | 60.83 | 54.85 | 61.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 209
- Matched controls
- 2090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I42.6
ICD-10 Finland
Alcoholic cardiomyopathy
+∞
246.7
185
*
I42.0
ICD-10 Finland
Dilated cardiomyopathy
+∞
75.7
68
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
15.7
69.1
70
65
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
10.0
52.8
76
113
C01AA05
ATC
digoxin; systemic
8.1
38.3
62
103
C03DA01
ATC
spironolactone; oral
6.5
32.9
68
144
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
+∞
31.0
29
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
11.2
30.6
35
37
P15
ICPC
Chronic alcohol abuse
9.5
27.8
36
45
4255A
ICD-9 Finland
Cardiomyopathy, Alcoholic cardiomyopathy
+∞
27.7
26
*
N07BB01
ATC
disulfiram; oral
7.9
25.6
39
59
K70.0
ICD-10 Finland
Alcoholic fatty liver
47.8
24.3
29
7
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
24.1
76
227
F10.25
ICD-10 Finland
Alcohol dependence continuous use
19.3
21.8
33
20
I50.1
ICD-10 Finland
Left ventricular failure
6.5
20.4
37
67
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
24.5
17.3
24
11
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
17.3
16.7
26
17
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
15.6
15.5
25
18
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
22.1
15.5
22
11
C03CA01
ATC
furosemide; systemic
3.2
15.5
105
500
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
18.3
15.2
23
14
N05AA02
ATC
levomepromazine; systemic
6.8
14.5
24
39
A98
ICPC
Health maint/preventive medicine
0.3
14.4
124
1720
I50.0
ICD-10 Finland
Congestive heart failure
4.5
14.3
39
101
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
14.3
13.3
22
17
F10.20
ICD-10 Finland
Alcohol dependence currently independent
11.6
13.1
24
23
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
40.1
12.4
15
*
F10.24
ICD-10 Finland
Alcohol depence active use
12.1
12.4
22
20
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
12.1
12.4
22
20
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
17.8
11.9
18
11
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.2
11.8
26
56
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
14.8
11.7
19
14
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
37.3
11.4
14
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
8.8
10.9
23
29
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
13.9
10.9
18
14
N05BA02
ATC
chlordiazepoxide; systemic
10.4
10.5
20
21
C09DX04
ATC
valsartan and sacubitril; oral
34.5
10.5
13
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
12.2
10.3
18
16
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
9.9
55
225
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.6
9.7
75
365
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
9.7
60
261
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
5.3
9.5
20
41
N05BA01
ATC
diazepam; systemic, rectal
3.2
9.3
42
152
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.7
9.3
21
30
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.2
9.1
8
391
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
10.2
9.0
17
18
N05CD07
ATC
temazepam; oral
3.2
8.9
41
150
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
8.9
60
271
K70.4
ICD-10 Finland
Alcoholic hepatic failure
52.2
8.8
10
*
S82.6
ICD-10 Finland
Fracture of lateral malleolus
4.7
8.3
20
46
K70.1
ICD-10 Finland
Alcoholic hepatitis
23.1
8.1
11
5
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
19.2
7.7
11
6
1CX08, ,
NOMESCO Finland
82.9
7.5
8
*
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
7.3
7
*
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
+∞
7.3
7
*
207
Kela drug reimbursment
Chronic arrhythmias
2.6
7.0
49
223
B01AA03
ATC
warfarin; systemic
2.4
7.0
59
293
N05BA04
ATC
oxazepam; oral
2.4
7.0
59
294
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.8
6.9
13
14
N40
ICD-10 Finland
Hyperplasia of prostate
0.4
6.7
29
656
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
6.1
6.6
17
30
K78
ICPC
Atrial fibrillation/flutter
3.2
6.5
27
92
Z72.1
ICD-10 Finland
Alcohol use
9.7
6.4
12
13
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
9.7
6.4
12
13
4259X
ICD-9 Finland
Cardiomyopathy, Secondary cardiomyopathy, unspecified
+∞
6.3
6
*
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
6.3
6
*
4254A
ICD-9 Finland
Cardiomyopathy, Other primary cardiomyopathies
+∞
6.3
6
*
M01AH05
ATC
etoricoxib; oral
0.5
6.2
57
949
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.1
6.1
17
44
P16
ICPC
Acute alcohol abuse
7.6
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
125
1765
0.27
17.81
50.9
26.4
217.28
233.38
e9/l
1.61
120
1733
125
1765
0.27
17.81
50.6
26.3
4.30
4.56
e12/l
5.43
120
1728
111
1659
0.29
16.78
5.6
6.2
2.45
2.61
mmol/l
1.08
100
1545
106
1621
0.30
16.63
4.9
5.4
1.27
1.33
mmol/l
0.77
95
1504
107
1623
0.30
16.23
5.0
5.5
4.33
4.42
mmol/l
0.36
96
1515
63
218
3.71
15.56
3.7
2.2
2.17
1.67
%
1.50
55
187
124
1726
0.31
14.88
19.9
12.8
36.62
28.91
u/l
2.84
119
1683
67
1231
0.33
12.83
4.0
5.2
2.19
2.55
ug/l
0.34
58
1121
111
1602
0.35
12.74
5.4
5.4
6.44
6.15
mmol/l
0.88
97
1482
108
1576
0.35
12.57
4.5
4.6
1.62
1.35
mmol/l
2.41
95
1453
112
1587
0.37
11.38
38.5
17.2
83.52
79.04
ml/min/173m2
1.12
106
1479
112
1582
0.37
11.09
6.5
7.0
41.05
40.37
mmol/mol
0.23
98
1500
36
113
3.64
10.01
5.5
3.5
24.11
23.97
mmol/l
0.09
36
113
120
1624
0.39
9.95
39.4
17.9
31.73
27.98
mg/l
0.67
113
1371
50
992
0.35
9.94
3.8
4.4
18.89
21.45
%
0.91
23
481
49
202
2.86
8.64
5.3
3.9
2.53
1.62
mmol/l
0.78
44
171
50
209
2.83
8.59
5.3
4.0
5.82
5.73
kpa
0.22
50
203
39
144
3.10
8.33
3.2
2.9
27.15
36.11
u/l
0.85
34
123
42
165
2.93
8.05
2.4
2.6
0.21
0.21
g/l
0.03
37
151
108
1460
0.46
6.95
4.6
4.3
1.91
2.01
mu/l
0.46
97
1315
39
176
2.49
5.63
5.1
3.1
4.46
4.49
kpa
0.03
39
169
54
890
0.47
5.41
3.4
2.6
—
—
—
0
0
78
1135
0.50
5.41
3.8
3.4
15.32
14.80
pmol/l
0.89
71
1019
41
728
0.46
4.90
2.3
3.3
0.61
0.79
ug/l
0.92
33
474
39
702
0.45
4.82
5.6
3.8
0.00
0.03
estimate
0.78
12
168
38
676
0.46
4.46
1.7
2.1
1.88
1.41
mmol/l
1.34
32
563
39
196
2.22
4.39
3.0
4.0
17.91
10.27
umol/l
0.58
33
177
93
1230
0.56
4.07
3.6
4.2
16.91
12.17
mm/h
1.61
86
1145
27
505
0.47
3.48
5.0
3.4
0.00
0.01
estimate
0.50
12
155
63
900
0.57
3.39
4.3
3.9
0.00
0.00
estimate
-0.00
11
174
12
34
3.68
3.25
1.4
1.5
—
—
—
0
0
12
34
3.68
3.25
1.4
1.5
—
—
—
0
0
6
194
0.29
3.14
3.0
4.3
2.83
74.01
ug/l
—
6
169
62
876
0.58
3.11
3.8
3.9
0.00
0.00
estimate
-0.00
12
192
63
885
0.59
3.08
4.3
3.9
0.00
8.33
estimate
0.50
12
195
42
247
1.88
3.06
24.5
9.0
1.29
0.72
mmol/l
0.22
37
204
12
275
0.40
2.54
3.3
2.4
10.93
13.91
nmol/l
0.48
12
250
22
110
2.12
2.52
1.6
1.5
—
—
—
0
0
31
505
0.55
2.51
5.7
3.8
0.00
0.01
estimate
0.50
12
168
6
13
4.72
2.29
1.0
2.2
95.17
91.92
%
—
6
13
78
584
1.54
2.26
3.7
3.8
51.85
35.97
u/l
1.75
73
555
38
248
1.65
1.94
2.3
2.0
—
—
—
0
0
20
108
1.94
1.89
1.7
1.7
—
—
—
0
0
8
29
2.83
1.81
5.6
3.6
—
—
—
0
0
8
177
0.43
1.80
3.8
2.9
0.29
0.19
e6/l
—
8
171
5
13
3.91
1.72
2.2
1.7
—
—
—
0
0
9
189
0.45
1.72
2.3
1.4
—
—
—
0
0
38
256
1.59
1.72
2.2
1.9
—
—
—
0
0
10
202
0.47
1.56
29.8
8.7
—
—
—
0
0
115
1309
0.73
1.43
13.4
9.0
89.27
80.99
u/l
1.05
110
1246
61
767
0.71
1.43
7.5
4.0
31.09
45.46
ng/l
1.12
50
594
0
40
0.00
1.34
0.0
1.3
—
—
—
0
0
8
34
2.41
1.30
1.0
1.2
—
—
—
0
0
57
447
1.38
1.21
3.1
2.0
2.53
2.96
mg/l
0.87
52
394
5
20
2.54
1.16
1.2
1.3
187.20
312.00
u/l
—
5
20
53
661
0.73
1.13
3.7
4.1
19.24
10.13
mg/mmol
0.46
41
438
55
682
0.74
1.13
2.0
2.4
64.61
73.32
nmol/l
1.01
50
605
26
366
0.67
1.11
2.3
1.8
448.56
37864509.22
pmol/l
0.50
18
309
28
388
0.68
1.10
5.9
4.2
1.02
1.02
kg/l
0.10
22
261
10
52
1.97
1.08
1.5
1.3
—
—
—
0
0
7
34
2.09
1.04
1.0
1.2
348.86
274.75
u/ml
—
7
16
43
331
1.38
1.02
2.4
2.0
—
—
—
0
0
10
54
1.89
0.98
1.2
1.4
—
—
—
0
0
0
30
0.00
0.98
0.0
4.1
—
1147.83
—
0
6
25
176
1.48
0.96
4.6
2.7
7.97
8.41
ug/l
0.04
25
159
42
328
1.35
0.92
3.1
3.0
1.87
1.02
e6/l
0.35
28
192
63
532
1.26
0.79
3.3
3.2
1.33
0.45
e6/l
0.84
51
397
7
38
1.87
0.74
2.0
1.3
—
—
—
0
0
7
38
1.87
0.74
2.0
1.3
—
—
—
0
0
5
92
0.53
0.68
3.2
1.8
198.60
213.84
pmol/l
—
5
82
5
94
0.52
0.68
1.8
2.1
—
—
—
0
0
46
381
1.27
0.67
9.2
1.7
1.51
1.63
mg/l
0.14
36
309
11
70
1.60
0.66
1.0
3.2
1.42
2.80
ratio
—
5
37
38
308
1.29
0.66
3.2
3.2
1.40
0.60
e6/l
0.35
24
173
68
774
0.82
0.65
3.7
3.0
—
—
estimate
—
0
0
6
103
0.57
0.64
1.8
2.3
—
17.22
—
0
10
18
131
1.41
0.61
2.1
1.6
—
—
—
0
0
88
973
0.83
0.61
7.3
10.2
4.73
4.31
e9/l
0.86
76
845
102
928
1.19
0.60
12.2
7.6
15.34
12.70
umol/l
1.44
97
892
7
114
0.60
0.60
3.0
1.8
37.14
41.79
nmol/l
—
7
108
8
55
1.47
0.56
2.0
1.3
—
—
—
0
0
10
147
0.66
0.56
6.1
2.9
5.17
5.07
kpa
—
10
142
11
74
1.51
0.54
1.9
3.4
—
—
—
0
0
11
75
1.49
0.52
1.4
2.3
49.00
44.95
u/l
—
6
69
20
255
0.76
0.50
1.2
1.3
27.84
31.88
iu/ml
—
7
74
10
68
1.49
0.48
1.3
2.9
11.72
11.46
g/l
—
10
60
49
557
0.84
0.45
2.6
3.3
2.34
2.33
mmol/l
0.18
42
499
5
32
1.58
0.42
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
9.1
—
120.50
—
0
6
0
16
0.00
0.41
0.0
1.7
—
3.00
—
0
9
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
70
767
0.87
0.40
2.1
2.1
81.72
93.78
pmol/l
1.56
45
425
13
170
0.75
0.40
2.0
2.1
430.69
375.14
nmol/l
0.88
13
156
13
98
1.35
0.38
1.9
2.0
5.48
2.15
ug/l
0.42
13
90
12
92
1.32
0.32
1.5
1.5
1.35
1.45
g/l
0.22
12
86
90
844
1.12
0.30
16.3
8.2
1.16
1.20
mmol/l
3.42
78
732
28
242
1.18
0.30
16.5
4.7
235.00
234.39
u/l
0.01
28
230
23
195
1.20
0.30
5.3
3.5
—
—
—
0
0
19
222
0.84
0.25
1.1
1.3
14.18
7.37
u/ml
—
6
82
10
78
1.30
0.24
1.3
2.7
3.00
3.01
g/l
—
10
70
16
134
1.21
0.23
14.0
7.8
24.93
24.50
mmol/l
0.12
16
128
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
13.40
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
516.00
—
0
7
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
34.88
—
0
6
5
43
1.17
0.21
1.2
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.26
0.20
1.2
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
51
1.18
0.19
1.3
1.2
—
—
—
0
0
6
52
1.16
0.19
1.3
1.5
—
—
—
0
0
7
61
1.15
0.17
1.3
1.5
—
—
—
0
0
31
339
0.90
0.17
2.7
3.0
2.50
2.44
mmol/l
1.59
26
299
10
82
1.23
0.17
1.3
2.7
6.89
7.34
g/l
—
10
74
10
82
1.23
0.17
1.3
2.7
4.38
4.26
g/l
—
10
74
10
82
1.23
0.17
1.3
2.7
3.85
3.64
g/l
—
10
74
5
68
0.73
0.17
5.8
4.2
4.74
4.61
pmol/l
—
5
62
33
309
1.08
0.11
2.1
1.7
1286.58
1209.04
nmol/l
0.13
27
240
48
503
0.94
0.10
1.9
1.8
17.68
19.65
nmol/l
0.52
43
421
42
401
1.06
0.09
4.0
2.6
—
—
—
0
0
59
570
1.05
0.08
5.0
3.0
57.13
64.30
u/l
0.33
54
539
15
144
1.04
0.00
1.6
1.4
—
—
—
0
0
13
134
0.97
0.00
2.8
4.1
1.18
1.22
mmol/l
1.40
13
116
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
53.92
—
0
9
0
9
0.00
0.00
0.0
4.9
—
90.33
—
0
9
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
116.14
—
0
8
5
50
1.00
-0.00
1.4
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.7
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.4
—
4.66
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.11
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
33.09
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
41.69
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
100.00
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
7.24
—
0
5
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.4
—
10.18
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.2
—
65.10
—
0
5
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1481.13
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
12.67
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
68
0.88
-0.00
1.7
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.17
—
0
5
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
1.56
—
0
5
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
95.34
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.0
—
169.28
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
8.25
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint I9_CARDMYOALC and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_CARDMYOALC | 8.396 [6.95, 10.14] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 408 out of 630 males with I9_CARDMYOALC died.
Mortality risk
Mortality risk for people of age
years, who have I9_CARDMYOALC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.353% |
| 5 | No data | 8.938% |
| 10 | No data | 20.736% |
| 15 | No data | 36.196% |
| 20 | No data | 53.948% |
Relationships between endpoints
↥Index endpoint: I9_CARDMYOALC – Alcoholic cardiomyopathy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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