external ear disease: A disease involving the external ear. [database_cross_reference: MONDO:DesignPattern]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1563 |
4. Check minimum number of eventsNone |
1563 |
5. Include endpointsNone |
1563 |
6. Filter based on genotype QC (FinnGen only) |
1424 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified disorders of external ear
based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8281 | 2364 | 5883 |
| Only index persons | 7659 | 2206 | 5453 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.07 | 0.16 |
| Only index persons | 0.17 | 0.08 | 0.21 |
| Median age at first event (years) | |||
| Whole population | 54.74 | 53.01 | 55.43 |
| Only index persons | 55.12 | 53.64 | 55.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1424 | 395 | 1029 |
| Unadjusted period prevalence (%) | 0.38 | 0.14 | 0.47 |
| Median age at first event (years) | 60.73 | 59.50 | 61.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1465
- Matched controls
- 14650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H61.9
ICD-10 Finland
Disorder of external ear, unspecified
107.0
314.7
162
17
H61.8
ICD-10 Finland
Other specified disorders of external ear
6475.4
307.7
1248
13
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
660.6
233.6
225
*
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
1102.0
200.9
192
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
8.3
191.5
281
406
UDC00
NOMESCO Finland
Ear microscopy
6.5
159.3
297
550
H60.3
ICD-10 Finland
Other infective otitis externa
20.6
158.6
123
65
H60.8
ICD-10 Finland
Other otitis externa
15.2
151.1
137
99
DFF00
NOMESCO Finland
Pure tone audiometry
4.6
121.2
347
924
DC1AD
NOMESCO Finland
Temporalbone CT
25.1
117.0
83
35
H61.2
ICD-10 Finland
Impacted cerumen
5.9
112.8
222
427
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.0
109.1
400
1270
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
166.4
103.7
108
7
3808A
ICD-9 Finland
Disorders of external ear, Other disorders of external ear[EXOSTOSIS MEATUS ACUSTICI EXTERNI]
+∞
100.2
95
*
4112
FHL
Removal of ear canal tumor (eg exostosis)
810.5
79.1
77
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
57.1
416
1898
H60
ICD-10 Finland
Otitis externa
4.9
56.0
129
281
H29
ICPC
Ear symptom/complaint other
2.9
49.5
266
1028
H71
ICD-10 Finland
Cholesteatoma of middle ear
11.5
48.6
51
46
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
10.0
46.8
54
56
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.4
44.8
179
580
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.6
42.6
61
83
H70
ICPC
Otitis externa
6.8
42.3
67
102
H01
ICPC
Ear pain/earache
2.9
37.7
199
756
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
5.3
37.1
76
149
H60.4
ICD-10 Finland
Cholesteatoma of external ear
84.4
37.0
41
5
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.6
36.7
129
384
H13
ICPC
Plugged feeling ear
2.2
36.1
393
2087
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.3
33.7
132
421
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.2
33.6
140
463
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.9
32.8
51
76
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.2
32.6
367
1965
S02CA02
ATC
flumetasone and antiinfectives; otic
3.3
28.9
113
359
DAX08
NOMESCO Finland
Fitting of hearing aid
2.8
27.1
142
534
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.4
26.9
99
303
H81
ICPC
Excessive ear wax
2.0
26.5
341
1902
DBW99
NOMESCO Finland
Other operation on external auditory canal
+∞
26.1
25
*
H66.9
ICD-10 Finland
Otitis media, unspecified
3.3
26.1
102
324
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
9.3
25.7
31
34
H60.1
ICD-10 Finland
Cellulitis of external ear
8.8
25.5
32
37
DCD00
NOMESCO Finland
Myringoplasty
10.6
25.4
28
27
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
4.8
24.7
56
120
TDA90
NOMESCO Finland
Removal wax from ear
6.0
23.6
42
72
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
23.5
239
1216
DAB00
NOMESCO Finland
Excision of lesion of auricle
6.1
23.5
41
69
H04
ICPC
Ear discharge
3.6
23.4
80
233
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
23.3
421
2616
J01DB01
ATC
cefalexin; oral
2.0
22.6
1213
10325
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
6.0
22.2
39
66
S18
ICPC
Laceration/cut
1.7
21.9
762
5688
Z01.2
ICD-10 Finland
Dental examination
1.7
20.9
643
4624
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
20.5
653
4733
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.1
20.0
42
84
H02
ICPC
Hearing complaint
1.9
19.5
273
1553
A98
ICPC
Health maint/preventive medicine
3.4
18.4
1413
13029
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.2
17.9
37
73
E0000UV, ,
ATC
1.6
17.9
575
4138
L17
ICPC
Foot/toe symptom/complaint
1.7
17.5
451
3060
N02BE01
ATC
paracetamol; systemic, rectal
2.1
17.4
1308
11698
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
17.4
740
5688
H65.2
ICD-10 Finland
Chronic serous otitis media
5.5
17.2
33
61
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
17.0
285
1712
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
16.9
300
1831
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.1
16.9
71
236
DFF15
NOMESCO Finland
Speech audiometry
2.5
16.6
103
422
M01AH05
ATC
etoricoxib; oral
1.6
16.5
876
7059
J01CA04
ATC
amoxicillin; systemic
1.7
16.4
1150
9930
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
15.9
482
3395
H61.0
ICD-10 Finland
Perichondritis of external ear
60.7
15.8
18
*
M79.6
ICD-10 Finland
Pain in limb
1.6
15.8
611
4560
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.4
15.5
39
91
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.6
15.4
419
2867
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
15.3
208
1165
H92.0
ICD-10 Finland
Otalgia
2.6
15.1
86
337
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
14.7
70
250
D82
ICPC
Teeth/gum disease
1.6
14.7
496
3571
K02.1
ICD-10 Finland
Caries of dentine
1.5
14.6
802
6432
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
14.6
1006
8492
L08
ICPC
Shoulder symptom/complaint
1.7
14.4
349
2313
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
14.4
634
4843
H65.0
ICD-10 Finland
Acute serous otitis media
4.7
14.3
33
72
R01AD12
ATC
fluticasone furoate; nasal
1.6
14.2
390
2666
R01AD08
ATC
fluticasone; nasal
1.6
14.1
371
2508
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
14.0
579
4355
4111
FHL
Ear canal extension
75.9
13.6
15
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
13.6
322
2119
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
4.6
13.6
32
71
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
13.2
186
1052
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.6
13.2
383
2648
ZXA05
NOMESCO Finland
Left side
1.6
13.2
362
2470
ZXA00
NOMESCO Finland
Right side
1.6
12.9
386
2686
Z71.8
ICD-10 Finland
Other specified counselling
1.6
12.9
449
3237
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.8
639
4974
M54.5
ICD-10 Finland
Low back pain
1.5
12.8
492
3624
J02AC01
ATC
fluconazole; systemic
1.6
12.7
409
2892
SFA20
NOMESCO Finland
Two-surface restoration
1.5
12.5
780
6340
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
12.5
578
4421
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
5.7
12.4
23
41
SPAT1043
SPAT
Audiometry
1.9
12.3
169
948
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
12.3
522
3920
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
12.3
745
6016
J01MA02
ATC
ciprofloxacin; systemic
1.5
12.2
578
4436
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
12.1
399
2832
M01AE02
ATC
naproxen; oral, rectal
1.5
12.1
740
5977
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
12.1
306
2042
H02AB06
ATC
prednisolone; systemic
1.5
12.0
672
5330
H60.0
ICD-10 Finland
Abscess of external ear
13.5
11.9
20
15
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
11.9
383
2704
D01BA02
ATC
terbinafine; oral
1.6
11.9
400
2853
J01DA01
ATC
[U] cefalexin
1.5
11.8
828
6857
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
11.8
422
3049
S29
ICPC
Skin symptom/complaint other
1.6
11.8
290
1920
J01AA02
ATC
doxycycline; systemic
1.5
11.5
1079
9452
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
11.5
391
2790
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
11.4
191
1137
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
11.2
503
3801
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
11.2
1254
11401
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
11.1
955
8184
M01AB05
ATC
diclofenac; systemic, rectal
1.5
11.0
910
7729
J01FA10
ATC
azithromycin; systemic
1.5
11.0
700
5658
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
10.9
538
4138
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
10.8
731
5969
L03
ICPC
Low back symptom/complaint
1.5
10.7
374
2679
X58
ICD-10 Finland
Exposure to other specified factors
1.7
10.6
217
1367
D07AC13
ATC
mometasone; topical
1.5
10.5
389
2818
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
10.5
277
1859
L57.0
ICD-10 Finland
Actinic keratosis
1.8
10.5
177
1055
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
10.5
149
843
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.2
10.5
91
433
R74
ICPC
Upper respiratory infection acute
1.5
10.4
363
2596
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
10.4
260
1724
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
10.4
859
7260
J02AC02
ATC
itraconazole; systemic
1.7
10.3
221
1408
F29
ICPC
Eye symptom/complaint other
1.8
10.2
146
829
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
10.2
182
1104
N02BF02
ATC
pregabalin; oral
2.1
10.1
96
472
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
9.9
377
2743
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.9
9.8
44
153
R01AD09
ATC
mometasone; nasal
1.4
9.7
555
4366
N03AX16
ATC
[U] pregabalin
1.5
9.7
311
2183
WX002
NOMESCO Finland
Sedation and analgesia
1.6
9.7
278
1903
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
9.7
561
4427
R06AX27
ATC
desloratadine; oral
1.5
9.6
316
2229
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
9.5
313
2205
M03BX02
ATC
tizanidine; oral
1.4
9.5
801
6744
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.5
368
2685
A02BC02
ATC
pantoprazole; systemic
1.4
9.5
961
8358
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
9.5
141
810
D07AC01
ATC
betamethasone; topical
1.4
9.5
496
3837
H27
ICPC
Fear of ear disease
4.2
9.5
25
61
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.4
562
4453
DBD10
NOMESCO Finland
Reconstruction of external auditory canal
+∞
9.4
9
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
9.4
279
1923
L15
ICPC
Knee symptom/complaint
1.5
9.3
328
2344
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
9.3
342
2466
TDA10
NOMESCO Finland
Needle biopsy of auricle or external auditory canal
9.6
9.3
18
19
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
9.1
185
1162
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
9.1
9.0
18
20
J05AB01
ATC
aciclovir; systemic
1.6
9.0
269
1856
J01FF01
ATC
clindamycin; systemic
1.5
8.9
371
2741
H93.1
ICD-10 Finland
Tinnitus
2.0
8.9
101
531
A02BC05
ATC
esomeprazole; systemic
1.4
8.9
534
4223
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
12.6
8.9
15
12
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.8
8.9
148
880
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
6.9
8.8
21
31
J01FA09
ATC
clarithromycin; systemic
1.5
8.8
380
2825
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.8
199
1284
L29
ICPC
Musculoskeletal sympt/complt other
1.8
8.8
122
686
SPAT1312
SPAT
General health counselling
1.5
8.8
400
3007
R05
ICD-10 Finland
Cough
1.5
8.8
281
1967
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.7
311
2225
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.9
8.7
105
564
AA1AD
NOMESCO Finland
CT of head and brain
1.4
8.7
440
3372
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.6
713
5949
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
8.5
243
1656
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.1
8.5
83
413
L13
ICPC
Hip symptom/complaint
1.5
8.5
256
1767
G44.2
ICD-10 Finland
Tension-type headache
1.7
8.4
154
939
ZXE00
NOMESCO Finland
One hour or less
1.4
8.4
502
3960
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.8
8.3
120
683
WX320
NOMESCO Finland
Spinalanesthesy
1.5
8.1
348
2581
UJF32
NOMESCO Finland
Coloscopy
1.4
8.1
371
2787
M75.2
ICD-10 Finland
Bicipital tendinitis
2.8
8.1
40
147
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
9.0
8.0
16
18
S83.2
ICD-10 Finland
Tear of meniscus, current
1.9
7.9
101
554
SDA03
NOMESCO Finland
Periodontal treatment
1.4
7.9
501
3983
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.2
7.8
61
278
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
7.8
147
903
S82
ICPC
Naevus/mole
1.6
7.8
181
1175
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
7.8
116
668
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.7
426
3302
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.7
139
844
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
2.3
7.7
56
248
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
4.5
7.7
18
40
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
7.6
56
249
K08.80
ICD-10 Finland
Toothache NOS
1.8
7.6
104
582
J01DA09
ATC
[U] cefadroxil
1.4
7.6
325
2408
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
7.5
487
3875
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.2
7.5
63
296
R06.5
ICD-10 Finland
Mouth breathing
1.7
7.5
139
851
R42
ICD-10 Finland
Dizziness and giddiness
1.5
7.4
304
2230
DBB02
NOMESCO Finland
Excision of a neoplasm from external auditory canal
80.5
7.4
8
*
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.4
311
2293
M48.0
ICD-10 Finland
Spinal stenosis
1.6
7.4
183
1206
D07AB08
ATC
desonide; topical
1.7
7.4
134
816
ZXD20
NOMESCO Finland
Day surgery
1.6
7.4
157
997
J37.0
ICD-10 Finland
Chronic laryngitis
2.4
7.4
51
221
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
7.4
296
2164
T78.4
ICD-10 Finland
Allergy, unspecified
2.4
7.4
50
215
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
4.0
7.4
20
50
SPAT1153
SPAT
Removal of sutures
1.4
7.4
446
3509
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
+∞
7.3
7
*
G04CA01
ATC
alfuzosin; oral
1.5
7.2
263
1884
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.9
7.2
88
475
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.2
7.2
28
90
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.6
7.1
172
1126
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.9
7.1
83
441
D07AD01
ATC
clobetasol; topical
1.5
7.1
203
1381
S06
ICPC
Rash localized
2.0
7.0
78
408
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
7.0
254
1818
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
7.0
369
2831
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.0
7.0
69
346
EB1VA, ,
NOMESCO Finland
1.5
7.0
225
1572
XF402
NOMESCO Finland
ECG with work load test
1.6
7.0
160
1036
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
7.0
131
806
L14
ICPC
Leg/thigh symptom/complaint
1.8
6.9
111
653
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
6.9
57
267
D02
ICPC
Abdominal pain epigastric
1.9
6.8
79
419
J34.2
ICD-10 Finland
Deviated nasal septum
1.9
6.8
87
477
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
6.8
192
1303
ECA30
NOMESCO Finland
Excision of lesion of gingiva
3.8
6.8
20
53
L28
ICPC
Limited function/disability (L)
1.5
6.8
256
1845
SFA30
NOMESCO Finland
Three-surface restoration
1.3
6.8
564
4649
M25.5
ICD-10 Finland
Pain in joint
1.4
6.8
402
3142
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
6.8
151
970
B37.0
ICD-10 Finland
Candidal stomatitis
4.3
6.8
17
40
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
3.1
6.8
27
88
DCD10
NOMESCO Finland
Tympanoplasty
16.8
6.7
10
6
TDA90, ,
SPAT
1.8
6.7
106
621
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.9
6.7
80
430
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.7
179
1202
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.6
254
1837
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.6
467
3753
SPAT1325
SPAT
Vaccination
1.4
6.6
440
3504
R06AE07
ATC
cetirizine; oral
1.4
6.6
491
3978
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
6.6
128
794
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.6
177
1190
PD5AD
NOMESCO Finland
CT of aorta
2.3
6.5
48
214
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.8
6.5
97
558
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
6.5
140
891
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
6.5
93
529
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
3.1
6.5
26
85
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
6.5
880
7773
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.4
481
3898
WX290
NOMESCO Finland
Other blockage of nerve
1.3
6.4
573
4767
SPAT1172
SPAT
Guidance concerning hydration
2.9
6.4
29
102
M79.1
ICD-10 Finland
Myalgia
1.6
6.3
171
1149
H57.1
ICD-10 Finland
Ocular pain
2.3
6.3
48
217
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.6
6.3
20
56
R51.80
ICD-10 Finland
Headache
1.5
6.3
173
1167
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.6
6.3
157
1036
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
+∞
6.3
6
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.2
346
2671
R03AC02
ATC
salbutamol; inhalant
1.3
6.2
679
5801
J33.8
ICD-10 Finland
Other polyp of sinus
2.4
6.2
39
162
R06AX13
ATC
loratadine; oral
1.6
6.2
151
991
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.8
6.2
99
582
N01
ICPC
Headache
1.7
6.2
115
705
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.2
320
2441
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
1.8
6.2
91
522
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
5.0
6.2
18
36
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.1
6.2
59
293
N06AX21
ATC
duloxetine; oral
1.6
6.2
133
848
H91.1
ICD-10 Finland
Presbycusis
1.7
6.1
99
584
ZXA10
NOMESCO Finland
Bilateral
1.5
6.1
229
1647
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.1
397
3147
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.1
213
1514
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.8
6.1
95
556
L90
ICPC
Osteoarthrosis of knee
1.8
6.0
92
534
W19
ICD-10 Finland
Unspecified fall
1.6
6.0
135
869
L01
ICPC
Neck symptom/complaint
1.5
6.0
183
1263
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.5
6.0
193
1347
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
303
1623
2.09
26.29
5.6
5.1
32.58
31.99
%
0.37
205
1084
875
6901
1.67
19.41
2.8
2.7
—
—
—
0
0
1332
11953
2.26
18.31
21.1
17.8
78.21
78.35
ml/min/173m2
0.10
1252
11176
1409
12982
3.23
18.20
14.5
12.9
27.26
27.43
u/l
0.12
1367
12617
989
8121
1.67
18.10
5.3
5.7
6.75
6.84
mmol/l
0.72
951
7789
1431
13330
4.17
17.67
32.1
27.7
136.29
136.29
g/l
0.00
1421
13182
1430
13323
4.07
17.48
32.0
27.6
234.97
240.01
e9/l
2.46
1411
13063
1430
13325
4.06
17.43
31.8
27.4
91.54
91.50
fl
0.13
1419
13180
1430
13327
4.06
17.39
32.4
28.2
40.69
40.94
%
0.30
1420
13172
1430
13327
4.06
17.39
32.0
27.6
6.77
6.87
e9/l
0.89
1404
13018
1430
13327
4.06
17.39
31.9
27.5
4.49
4.50
e12/l
0.28
1404
13019
784
6117
1.61
17.27
2.2
2.2
94.37
93.24
pmol/l
0.27
417
3492
1323
11892
2.16
17.25
7.7
6.9
39.94
39.98
mmol/mol
0.04
1212
11132
1387
12748
2.65
16.62
25.2
22.2
139.74
139.69
mmol/l
0.33
1369
12522
1413
13119
3.17
16.41
27.8
24.2
85.34
84.32
umol/l
0.41
1401
12979
1350
12277
2.27
16.33
21.3
18.4
25.98
27.27
mg/l
0.67
1169
10301
1268
11281
1.92
16.21
5.5
4.9
2.28
1.98
mu/l
0.48
1125
10371
1387
12771
2.62
16.13
25.4
22.4
4.01
4.01
mmol/l
0.22
1366
12536
1363
12477
2.33
15.65
6.7
6.1
2.58
2.58
mmol/l
0.11
1240
11599
1329
12069
2.09
15.21
6.0
5.5
6.05
6.07
mmol/l
0.16
1200
11083
1104
9497
1.66
15.16
4.7
4.3
12.70
12.63
mm/h
0.04
1009
8861
1005
8458
1.60
15.00
5.4
4.6
929.89
1060.52
e6/l
—
9
149
1337
12198
2.10
14.64
6.0
5.3
1.40
1.38
mmol/l
0.62
1220
11311
1342
12265
2.12
14.55
6.0
5.4
4.43
4.44
mmol/l
0.06
1228
11464
1294
11684
1.92
14.44
5.0
4.5
1.31
1.31
mmol/l
0.04
1170
10746
841
6831
1.54
14.38
19.3
17.4
1.32
1.31
inr
0.17
709
5740
692
5405
1.53
14.05
4.5
4.1
37.13
83.90
ng/l
1.88
532
4127
1146
10051
1.64
13.50
9.7
8.9
77.26
81.28
u/l
2.99
1091
9593
465
3397
1.54
12.48
2.4
2.7
—
—
—
0
0
858
7202
1.46
11.10
7.3
7.2
11.94
12.56
umol/l
0.53
811
6900
1053
9211
1.51
10.99
4.3
3.9
14.74
14.89
pmol/l
1.08
932
8403
823
6881
1.45
10.68
7.7
8.3
1.21
1.20
mmol/l
2.15
704
5942
583
4575
1.46
10.60
3.2
3.4
1616.15
1507.01
ng/l
0.23
480
4021
251
1643
1.64
10.57
2.7
2.4
13.15
13.36
nmol/l
0.14
216
1477
392
2845
1.52
10.53
1.7
1.7
1.03
1.44
mg/l
2.18
306
2249
971
8415
1.46
10.13
4.0
3.5
49.25
55.58
u/l
1.78
890
7909
557
4379
1.44
9.83
2.4
2.3
207.55
255.08
u/l
0.74
520
4162
181
1108
1.72
9.80
3.8
3.9
5.11
5.13
kpa
0.15
165
1074
753
6265
1.42
9.60
2.9
3.0
—
—
estimate
—
0
0
109
586
1.93
9.01
4.0
4.1
24.79
24.88
mmol/l
0.12
95
554
743
6210
1.40
9.00
7.0
7.5
1.21
1.20
mmol/l
1.17
674
5756
520
4106
1.41
8.69
1.8
1.8
19.14
19.49
nmol/l
0.22
410
3524
669
5526
1.39
8.53
2.5
2.4
77.62
76.78
nmol/l
0.31
569
4973
728
6114
1.38
8.30
5.0
5.7
35.52
35.11
g/l
1.09
673
5753
539
4315
1.39
8.20
2.7
2.8
56.88
60.25
u/l
0.82
490
4031
868
7552
1.37
7.66
9.4
9.9
4.30
4.29
e9/l
0.02
753
6555
136
836
1.69
7.24
2.4
2.5
20.05
15.94
au/ml
0.32
14
70
30
102
2.98
6.98
2.2
1.4
273.92
291.66
mu/l
0.19
24
80
149
947
1.64
6.98
3.9
3.8
1.33
1.88
mmol/l
1.15
111
707
417
3276
1.38
6.86
2.9
2.7
3.98
4.21
e6/l
0.16
388
2997
569
4721
1.34
6.49
4.1
3.5
32.89
97.64
e6/l
2.48
460
3679
829
7288
1.32
6.16
7.0
5.8
3.00
3.03
ug/l
0.02
740
6604
338
2607
1.39
6.12
1.3
1.3
0.84
1.60
u/ml
2.38
81
733
122
764
1.65
6.07
1.3
1.3
59.74
58.27
au/ml
0.03
12
57
494
4050
1.33
6.01
3.9
3.4
0.41
0.46
e6/l
0.23
385
3033
67
355
1.93
5.86
1.9
1.4
8.03
8.64
u/l
0.15
48
283
541
4532
1.31
5.54
3.7
3.7
2.35
2.34
mmol/l
1.32
471
4115
466
3829
1.32
5.48
3.2
3.1
357.09
361.61
umol/l
0.43
396
3378
88
520
1.74
5.45
2.0
1.9
—
—
—
0
0
327
2554
1.36
5.41
2.1
2.0
—
—
—
0
0
250
1868
1.41
5.41
5.4
4.3
231.82
249.42
u/l
1.76
238
1777
94
567
1.70
5.41
2.1
2.0
—
—
—
0
0
522
4367
1.30
5.36
3.8
3.4
0.80
0.77
ug/l
0.18
351
2952
592
5042
1.29
5.29
3.7
3.5
8.04
8.01
mmol/l
0.05
481
4281
215
1572
1.43
5.25
7.5
7.7
—
—
—
0
0
142
958
1.53
5.19
2.0
1.7
—
—
—
0
0
312
2438
1.36
5.13
1.9
1.8
1059.56
1145.72
nmol/l
0.62
213
1892
117
771
1.56
4.76
1.5
1.5
—
—
—
0
0
781
6945
1.27
4.74
4.4
3.9
0.00
0.24
estimate
0.55
166
1361
661
5764
1.27
4.72
3.2
3.1
157.02
162.29
ug/l
0.19
606
5372
195
1430
1.42
4.68
2.0
2.4
129.84
154.20
ug/g
0.52
151
1164
28
115
2.46
4.64
1.5
1.3
16.90
24.75
u/l
0.54
19
96
768
6832
1.26
4.58
4.3
3.8
0.00
0.00
estimate
-0.00
174
1468
775
6917
1.26
4.43
4.4
3.9
0.00
2.36
estimate
0.80
176
1485
38
184
2.09
4.33
1.1
1.1
4.02
1.69
u/ml
0.46
22
108
313
2511
1.31
4.23
2.7
2.8
12.36
12.80
umol/l
0.50
286
2347
67
397
1.72
4.17
1.5
1.6
9.34
19.50
u/ml
1.41
14
94
295
2367
1.31
3.97
1.7
1.5
2.61
2.72
g/l
0.45
179
1492
413
3467
1.27
3.89
4.2
4.5
85.66
85.06
%
0.19
407
3407
35
172
2.06
3.87
1.8
2.2
12.25
17.30
mg/l
—
8
67
277
2212
1.31
3.85
2.8
2.9
21.50
22.85
%
1.01
253
2073
64
385
1.69
3.80
1.4
1.6
—
—
—
0
0
294
2373
1.30
3.78
1.8
2.1
30.50
30.02
s
0.53
285
2313
31
147
2.13
3.76
1.0
1.1
4.36
1.24
u/ml
0.62
18
78
257
2043
1.31
3.69
1.4
1.3
9.54
11.34
u/ml
0.16
89
773
85
554
1.57
3.68
1.8
1.9
42.25
40.78
nmol/l
0.23
80
537
515
4459
1.24
3.66
3.0
3.4
32.53
39.28
u/l
0.73
477
4210
565
4946
1.23
3.61
4.6
4.3
12.11
9.33
mg/mmol
0.32
348
3265
434
3700
1.25
3.53
2.4
2.3
2.74
2.87
mg/l
0.65
365
3210
70
446
1.60
3.36
2.0
1.9
204.48
208.91
pmol/l
0.11
65
422
327
2716
1.26
3.32
3.2
3.2
2.45
2.45
mmol/l
0.27
295
2450
289
2365
1.28
3.31
2.7
2.8
2.27
2.25
g/l
0.22
262
2196
173
1321
1.35
3.28
3.1
2.9
65.63
66.42
g/l
0.70
155
1239
61
383
1.62
3.13
1.3
1.4
—
—
—
0
0
451
3909
1.22
3.08
4.6
4.0
0.02
0.00
estimate
0.34
158
1321
266
2177
1.27
3.04
1.4
1.3
32.54
35.25
iu/ml
0.12
88
650
285
2370
1.25
2.84
4.0
3.3
1.46
1.24
e6/l
0.20
160
1241
100
715
1.43
2.83
2.2
2.0
1.61
2.56
ug/l
0.57
84
650
236
1923
1.27
2.80
2.0
1.8
—
—
—
0
0
21
97
2.18
2.77
1.6
1.5
93.43
86.46
umol/l
0.59
21
97
207
1662
1.29
2.76
1.4
1.4
—
—
—
0
0
649
5881
1.19
2.66
4.7
4.8
21.88
21.66
%
0.14
333
2997
29
156
1.88
2.58
1.4
1.5
51.69
63.78
%
0.75
16
101
6
11
5.47
2.54
1.0
1.1
—
—
—
0
0
303
2568
1.23
2.53
3.8
3.1
0.72
0.88
e6/l
0.73
178
1442
157
1233
1.31
2.49
2.3
2.2
367.57
380.01
nmol/l
0.30
147
1162
107
795
1.37
2.46
2.4
1.8
—
—
—
0
0
136
1050
1.33
2.44
1.7
1.4
—
—
—
0
0
82
583
1.43
2.43
2.0
2.7
2.96
2.96
g/l
0.00
74
540
24
125
1.94
2.36
1.1
1.3
—
—
—
0
0
83
599
1.41
2.28
2.9
3.2
24.68
24.70
mmol/l
0.01
83
592
12
47
2.57
2.27
1.3
1.3
—
—
—
0
0
76
541
1.43
2.25
2.2
2.9
0.97
1.26
g/l
0.26
63
472
67
466
1.46
2.24
1.7
2.7
0.00
0.03
g/l
1.32
58
423
9
29
3.12
2.22
1.7
1.1
1.18
1.17
mmol/l
—
9
29
16
73
2.20
2.21
1.1
1.2
144.77
89.81
u/l
0.38
16
68
16
73
2.20
2.21
1.1
1.2
63.15
28.89
u/l
0.43
16
68
33
195
1.71
2.20
6.1
5.7
352.12
354.20
umol/l
0.03
26
177
35
211
1.67
2.18
1.3
1.5
—
—
—
0
0
324
2805
1.20
2.17
4.8
4.2
312.82
741.09
ng/l
0.69
271
2346
18
88
2.06
2.11
1.1
1.2
—
—
—
0
0
28
160
1.76
2.10
1.1
1.5
—
—
—
0
0
28
161
1.75
2.06
1.1
1.5
—
—
—
0
0
28
161
1.75
2.06
1.1
1.5
—
—
—
0
0
193
1594
1.24
2.06
1.8
1.8
1.55
1.57
%
0.09
154
1367
63
442
1.44
2.04
2.1
1.8
—
—
—
0
0
71
511
1.41
2.01
1.0
1.1
—
—
—
0
0
587
5364
1.16
2.01
2.0
1.9
1.40
1.35
mmol/l
0.61
488
4465
143
1145
1.28
1.99
2.8
3.0
62.94
63.37
ml/min/173m2
0.06
68
490
179
1473
1.25
1.98
3.5
2.8
68.28
69.41
e9/l
0.16
130
1096
190
1577
1.24
1.94
2.5
2.9
6.61
9.42
umol/l
2.59
161
1427
128
1014
1.29
1.94
3.9
4.6
89.51
101.48
ng/l
1.02
112
902
43
283
1.54
1.91
1.1
1.2
1.48
6.59
u/ml
—
5
17
163
1336
1.25
1.87
2.6
2.5
6.94
7.34
ug/l
0.14
130
1222
16
304
0.52
1.87
3.4
3.7
38.54
28.60
mg/l
—
10
208
41
269
1.54
1.85
1.0
1.1
4.70
8.01
eliau/ml
—
5
25
83
623
1.35
1.85
2.0
2.6
7.36
7.33
g/l
0.05
74
579
45
303
1.50
1.82
1.9
1.5
27.11
26.18
iu/l
0.07
36
253
27
162
1.68
1.75
1.4
1.4
0.61
11.68
nmol/l
0.50
27
154
20
110
1.83
1.73
1.1
1.0
0.05
0.23
u/ml
—
7
46
53
373
1.44
1.73
1.6
1.6
8597.41
16703.75
e6/l
1.33
39
262
82
622
1.34
1.72
2.7
3.9
4.44
4.48
pmol/l
0.12
70
560
82
623
1.33
1.71
2.0
2.6
3.98
3.80
g/l
0.48
74
579
82
623
1.33
1.71
2.0
2.6
4.06
4.18
g/l
0.74
74
580
19
104
1.84
1.67
1.1
1.1
—
—
—
0
0
98
767
1.30
1.66
1.5
1.3
327.60
250.86
u/ml
0.16
92
717
8
31
2.59
1.66
1.4
1.5
—
—
—
0
0
62
454
1.38
1.64
1.7
2.7
0.00
0.00
g/l
-0.00
54
400
23
135
1.71
1.63
1.1
1.1
—
52.00
—
0
8
5
131
0.38
1.62
1.0
1.1
334.80
288.86
mg/l
—
5
122
170
1424
1.22
1.62
2.2
2.3
0.20
0.21
g/l
0.84
159
1329
18
98
1.85
1.62
1.3
1.5
18.20
21.29
u/ml
—
5
14
286
2513
1.17
1.61
3.7
3.6
0.82
0.82
mmol/l
0.09
265
2395
40
272
1.48
1.57
1.1
1.2
—
460.00
—
0
6
25
152
1.66
1.57
2.3
2.9
—
—
—
0
0
52
373
1.41
1.56
1.2
1.4
—
—
—
0
0
48
340
1.43
1.54
1.2
1.2
2.07
3.75
u/ml
—
7
28
22
130
1.70
1.53
1.0
1.1
2.35
1.68
u/ml
0.22
12
69
21
124
1.70
1.47
1.7
1.4
29.67
25.09
%
0.20
12
80
17
94
1.82
1.47
1.5
1.6
—
—
—
0
0
16
87
1.85
1.46
1.1
1.1
—
—
—
0
0
16
87
1.85
1.46
1.1
1.1
—
—
—
0
0
42
294
1.44
1.45
1.4
1.4
—
—
—
0
0
155
1303
1.21
1.44
2.8
2.5
29.55
76.00
u/l
0.67
131
1095
30
196
1.54
1.43
1.4
1.6
—
—
—
0
0
17
95
1.80
1.43
1.1
1.1
—
—
—
0
0
16
88
1.83
1.41
1.3
1.4
—
52.50
—
0
8
12
60
2.01
1.38
1.1
1.4
177.00
184.74
mmol/24h
0.19
12
60
107
870
1.25
1.37
2.5
1.9
—
—
—
0
0
42
298
1.42
1.36
1.3
1.5
—
—
—
0
0
15
82
1.84
1.36
1.1
1.2
—
—
—
0
0
14
75
1.88
1.34
1.4
1.6
80.66
120.78
ng/l
1.48
14
75
75
586
1.29
1.33
1.4
2.0
36.25
38.67
u/l
0.64
68
510
16
90
1.79
1.33
1.6
1.7
—
—
—
0
0
175
1501
1.19
1.33
4.3
3.6
—
—
—
0
0
47
343
1.38
1.31
1.3
1.4
—
—
—
0
0
24
154
1.57
1.26
1.1
1.5
—
—
—
0
0
24
154
1.57
1.26
1.1
1.5
—
—
—
0
0
24
155
1.56
1.23
1.1
1.5
—
—
—
0
0
51
382
1.35
1.23
1.5
1.6
—
—
—
0
0
46
340
1.36
1.21
1.2
1.2
11.88
5.09
u/ml
—
8
45
128
1078
1.21
1.20
2.6
2.8
10.57
10.86
g/l
0.22
114
1008
69
542
1.29
1.20
1.1
1.1
—
2.20
—
0
5
143
1218
1.19
1.19
3.2
3.1
285.13
213.21
ng/l
0.54
132
1119
552
5163
1.11
1.17
4.4
3.8
0.02
0.02
estimate
0.08
132
1232
35
248
1.42
1.17
5.1
4.1
1.10
1.51
%
0.39
29
228
22
141
1.57
1.17
1.0
1.1
—
1.91
—
0
24
206
1812
1.16
1.17
2.0
1.9
—
—
—
0
0
15
87
1.73
1.15
1.7
1.4
1.09
1.13
nmol/l
—
9
65
17
103
1.66
1.13
1.5
1.6
—
—
—
0
0
48
363
1.33
1.11
1.5
2.1
17.17
11.99
mg/l
0.54
43
332
58
451
1.30
1.10
3.7
3.1
1.68
1.64
mg/l
0.10
52
410
14
81
1.74
1.09
1.4
1.8
—
—
—
0
0
68
542
1.27
1.08
2.0
2.7
10.28
10.63
g/l
0.27
59
495
18
113
1.60
1.06
4.6
3.0
13.11
13.20
%
0.15
18
113
14
82
1.71
1.05
1.1
1.1
—
—
—
0
0
392
3621
1.11
1.04
3.9
3.4
0.00
0.04
estimate
1.11
138
1139
9
47
1.92
1.02
1.0
1.1
—
—
—
0
0
85
1020
0.82
0.98
7.1
7.6
25.08
24.40
mmol/l
0.93
79
973
44
337
1.32
0.96
1.6
1.5
—
—
—
0
0
14
85
1.65
0.94
1.4
2.4
—
—
—
0
0
45
347
1.31
0.94
1.2
1.2
—
—
—
0
0
52
409
1.28
0.94
1.4
1.6
—
—
—
0
0
32
234
1.38
0.94
4.6
3.7
10.75
9.41
pmol/l
0.22
32
234
63
510
1.25
0.91
3.3
3.5
4.54
3.17
ratio
0.18
30
304
34
253
1.35
0.90
1.3
1.5
—
—
—
0
0
39
297
1.32
0.90
1.2
1.6
0.81
0.87
nmol/l
0.24
32
250
175
1555
1.14
0.90
4.0
4.5
15.04
25.64
ug/l
0.41
137
1303
20
135
1.49
0.89
1.2
1.3
—
—
—
0
0
69
566
1.23
0.89
3.4
3.7
39.43
86.83
mg/l
0.99
57
484
69
567
1.23
0.88
3.4
3.7
49.59
63.29
mg/l
0.54
57
484
81
677
1.21
0.87
3.8
3.6
1.02
1.02
ratio
0.62
76
631
33
248
1.34
0.84
1.6
1.5
152.81
156.80
au/ml
0.08
16
76
44
346
1.28
0.82
1.3
1.2
—
—
—
0
0
33
250
1.33
0.80
2.5
2.0
1.37
1.73
mmol/l
3.35
33
242
11
66
1.67
0.78
2.0
1.3
1.55
2.78
u/field
0.50
11
46
10
163
0.61
0.78
2.3
2.6
1931.10
961.41
mg
—
10
163
14
90
1.56
0.78
1.1
1.2
—
—
—
0
0
14
90
1.56
0.78
4.4
6.1
50.96
30.36
u/ml
—
5
30
14
90
1.56
0.78
1.1
1.2
—
—
—
0
0
13
82
1.59
0.78
1.3
2.0
—
—
—
0
0
13
82
1.59
0.78
1.3
2.0
—
—
—
0
0
13
82
1.59
0.78
1.3
2.0
—
—
—
0
0
13
82
1.59
0.78
1.3
2.0
—
—
—
0
0
23
165
1.40
0.78
6.5
4.1
54.76
56.48
%
0.10
17
147
33
252
1.32
0.77
1.4
1.3
222.69
279.76
u/ml
0.59
21
141
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
76
644
1.19
0.74
1.3
1.2
87.49
140.98
u/ml
1.67
28
240
28
210
1.34
0.74
1.3
1.3
—
—
—
0
0
13
84
1.55
0.72
1.2
2.1
700.13
604.35
e6/l
—
8
71
17
117
1.46
0.72
1.8
1.8
0.90
1.69
u/field
—
10
61
9
57
1.58
0.71
1.1
1.0
—
—
—
0
0
29
221
1.32
0.70
1.6
1.5
2196.29
5569.31
e6/l
0.39
24
152
38
301
1.27
0.69
1.9
1.9
—
—
—
0
0
62
736
0.84
0.69
6.1
5.9
1.62
1.60
%
0.07
57
695
5
27
1.85
0.68
1.2
1.1
—
—
—
0
0
11
69
1.60
0.68
2.4
1.3
8.43
8.59
ug/l
0.02
11
59
18
127
1.42
0.68
1.5
1.7
—
—
—
0
0
55
457
1.21
0.67
1.2
1.3
—
—
—
0
0
117
1038
1.14
0.65
1.6
1.7
—
—
—
0
0
308
2880
1.09
0.65
1.9
1.8
439.06
24928194.20
pmol/l
2.13
234
2423
62
524
1.19
0.64
1.5
1.3
—
—
—
0
0
34
269
1.27
0.64
1.6
1.8
—
—
—
0
0
17
121
1.41
0.62
1.1
1.2
—
—
titre
—
0
0
19
139
1.37
0.60
1.3
1.7
—
—
—
0
0
19
139
1.37
0.60
1.3
1.7
—
—
—
0
0
19
139
1.37
0.60
1.3
1.7
—
—
—
0
0
48
399
1.21
0.60
1.3
1.5
344.84
268.25
ug/g
1.89
31
252
68
584
1.17
0.60
1.8
1.7
0.26
0.35
mg/l
1.00
31
297
12
174
0.69
0.59
1.1
1.1
117.92
113.97
%
0.28
12
160
10
64
1.57
0.58
1.1
1.2
97.20
216.50
iu/ml
—
10
64
19
140
1.36
0.58
1.3
1.3
342359.00
66234.87
e6/l
0.42
13
95
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
37
449
0.82
0.55
4.8
4.3
3.85
3.97
mmol/l
0.96
37
442
6
38
1.58
0.54
1.0
1.2
102.67
105.56
%
—
6
32
26
204
1.28
0.54
1.5
1.4
—
—
—
0
0
44
369
1.20
0.52
1.9
2.0
—
—
—
0
0
37
305
1.22
0.52
1.2
1.2
—
—
—
0
0
21
161
1.31
0.52
4.9
4.3
—
—
—
0
0
23
179
1.29
0.51
1.0
1.1
—
—
—
0
0
26
206
1.27
0.51
1.4
1.6
—
—
—
0
0
37
306
1.21
0.50
1.6
1.3
—
—
—
0
0
67
585
1.15
0.50
3.1
2.8
—
—
—
0
0
34
281
1.21
0.47
1.6
1.5
—
16.71
—
0
7
7
49
1.43
0.46
1.3
1.7
—
—
—
0
0
50
431
1.17
0.45
3.1
3.6
8.07
7.97
kpa
0.20
50
422
37
311
1.19
0.44
3.0
3.3
0.74
0.83
nmol/l
0.67
27
248
22
275
0.80
0.44
1.1
1.3
384.01
221.94
miu/ml
—
7
108
19
148
1.29
0.43
1.3
1.2
1.23
1.57
nmol/l
1.08
19
136
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
8
59
1.36
0.41
1.5
2.1
—
—
—
0
0
8
59
1.36
0.41
1.5
2.1
—
—
—
0
0
8
59
1.36
0.41
1.6
1.0
1440.88
1421.25
miu/ml
—
8
59
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
8
60
1.34
0.40
1.6
2.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.9
—
68.10
—
0
18
0
18
0.00
0.40
0.0
1.7
—
2.00
—
0
9
9
68
1.33
0.37
1.3
1.5
49.85
49.97
ug/l
—
9
68
21
170
1.24
0.37
1.2
1.3
265.00
319.82
pmol/l
0.48
21
145
10
72
1.39
0.37
4.8
3.4
2.80
0.99
%
—
10
72
6
43
1.40
0.35
4.7
2.0
131.83
131.19
nmol/l
—
6
37
34
292
1.17
0.34
1.4
1.3
—
—
—
0
0
34
292
1.17
0.34
1.4
1.3
—
—
—
0
0
6
45
1.33
0.33
1.2
1.3
—
—
—
0
0
159
1496
1.07
0.33
8.2
7.9
10.71
10.68
mmol/l
0.02
146
1439
6
88
0.68
0.33
1.0
1.4
—
—
—
0
0
6
89
0.67
0.33
1.0
1.4
—
—
—
0
0
23
192
1.20
0.32
1.6
1.5
114510.21
79818.30
e6/l
0.16
14
109
31
267
1.16
0.31
1.8
1.9
18.60
4.30
iu/l
—
7
97
7
52
1.35
0.31
1.1
1.1
—
—
—
0
0
7
53
1.32
0.31
1.1
1.2
12.71
9.68
mm/h
—
7
53
37
324
1.15
0.31
4.7
5.5
2063.67
820.70
iu/ml
—
6
46
116
1084
1.08
0.30
5.3
4.2
1.21
1.22
mmol/l
1.21
100
945
39
344
1.14
0.29
1.6
1.5
—
—
—
0
0
7
56
1.25
0.29
3.9
1.9
1.76
11.54
nmol/l
—
7
50
28
324
0.86
0.29
5.3
3.6
7.31
7.62
mmol/l
0.28
28
315
46
411
1.12
0.29
1.7
1.6
—
—
—
0
0
17
206
0.82
0.29
1.2
1.4
—
—
—
0
0
170
1613
1.06
0.29
5.1
3.9
1.64
1.81
mmol/l
0.26
151
1379
23
195
1.18
0.28
2.1
2.2
2529.77
4223.47
u/l
—
10
75
14
113
1.24
0.26
1.0
1.0
—
—
—
0
0
10
77
1.30
0.26
2.9
2.4
—
—
—
0
0
28
244
1.15
0.26
4.1
6.7
10.99
11.84
mg/l
0.55
28
230
13
159
0.82
0.24
1.8
1.8
—
—
—
0
0
9
76
1.19
0.24
1.1
1.0
—
—
—
0
0
153
1606
0.95
0.24
7.7
9.4
121.87
121.84
g/l
0.01
146
1569
15
179
0.84
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
3.2
1.6
129.80
239.87
nmol/24h
—
5
39
16
189
0.84
0.22
1.1
1.3
1.33
4.53
u/ml
—
6
75
198
1904
1.05
0.22
6.5
8.8
5.08
5.10
kpa
0.13
187
1832
10
79
1.27
0.22
1.2
1.4
—
—
—
0
0
10
79
1.27
0.22
1.2
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
62
574
1.08
0.22
2.5
2.8
0.43
0.34
iu/ml
1.04
38
317
198
1905
1.05
0.22
6.5
8.7
12.52
12.03
kpa
0.54
187
1836
37
334
1.11
0.21
3.6
2.8
14.92
16.29
%
1.74
37
326
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
103
0.78
0.21
1.3
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
40
365
1.10
0.19
4.7
3.5
1.82
1.61
index
0.12
24
201
11
133
0.83
0.19
1.1
1.1
105.18
96.31
%
0.56
11
125
10
81
1.24
0.18
2.9
3.7
—
—
—
0
0
10
81
1.24
0.18
1.3
2.1
—
—
—
0
0
33
299
1.11
0.18
1.5
1.3
8.04
42.67
e6/l
0.97
24
226
83
784
1.06
0.18
1.7
1.8
1.56
1.53
g/l
0.12
71
682
43
396
1.09
0.18
1.7
1.5
0.19
19.15
iu/ml
—
8
63
11
91
1.21
0.17
1.6
1.1
73.18
97.59
pmol/l
0.71
11
91
31
341
0.91
0.17
1.3
1.1
0.67
0.68
ratio
—
7
53
34
372
0.91
0.17
1.2
1.4
—
—
—
0
0
172
1662
1.04
0.17
5.2
3.9
5.90
5.82
kpa
0.47
167
1614
5
68
0.73
0.17
1.6
1.2
1.11
1.08
ratio
—
5
58
8
69
1.16
0.16
1.0
1.0
—
—
—
0
0
195
1891
1.04
0.16
6.5
8.7
0.66
0.85
mmol/l
0.29
161
1546
16
139
1.15
0.16
1.0
1.1
1.88
2.21
eliau/ml
—
6
53
18
158
1.14
0.16
1.3
2.0
—
1908.57
—
0
7
209
2030
1.03
0.16
6.9
6.9
1.08
1.04
mmol/l
0.93
191
1915
1021
10137
1.02
0.15
25.4
22.5
13.68
13.74
%
0.86
1013
10023
15
131
1.15
0.14
1.7
1.5
—
—
—
0
0
44
411
1.07
0.14
1.5
1.8
2.76
3.67
mg/l
0.33
31
311
33
305
1.08
0.13
1.6
1.4
505.96
505.85
e6/l
0.00
25
241
33
305
1.08
0.13
2.7
1.3
31.38
44.90
u/l
0.35
27
267
15
132
1.14
0.13
1.6
1.5
—
—
—
0
0
14
123
1.14
0.12
1.0
1.1
—
—
—
0
0
10
85
1.18
0.12
1.1
1.1
209.40
303.95
mg/l
—
10
76
17
188
0.90
0.11
1.2
1.2
4.63
6.39
u/ml
—
8
93
16
144
1.11
0.10
1.8
1.3
—
—
—
0
0
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
109
1122
0.97
0.09
1.9
2.1
3.51
3.59
ratio
0.24
84
911
5
46
1.09
0.09
7.2
7.0
53.40
71.97
%
—
5
36
13
145
0.90
0.09
1.7
1.9
—
—
—
0
0
6
55
1.09
0.09
1.0
1.3
—
—
—
0
0
169
1724
0.98
0.08
7.2
8.9
95.15
95.48
%
0.23
158
1668
12
107
1.12
0.08
1.4
1.4
133.37
250.90
pmol/l
0.69
12
107
5
62
0.81
0.08
1.0
1.5
—
—
—
0
0
5
62
0.81
0.08
1.0
1.5
—
—
—
0
0
79
815
0.97
0.08
1.7
1.8
3.29
3.42
mmol/l
0.39
55
599
7
67
1.05
0.08
1.6
4.1
14.69
64.09
u/ml
—
7
67
7
67
1.05
0.08
1.0
1.2
—
—
—
0
0
8
74
1.08
0.07
1.1
2.6
1222.88
1096.84
u/ml
—
8
74
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
80
0.87
0.07
1.1
1.2
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
35
367
0.95
0.07
1.4
1.2
1.49
1.51
g/l
0.20
35
367
9
87
1.03
0.07
1.4
1.7
—
—
—
0
0
11
99
1.11
0.06
1.4
1.6
11.99
14.56
umol/l
1.03
11
94
11
121
0.91
0.06
1.6
1.4
—
—
—
0
0
19
179
1.06
0.05
1.1
1.1
47.54
20.25
au/ml
—
5
41
10
93
1.08
0.02
1.6
1.6
—
—
—
0
0
95
941
1.01
0.01
1.7
1.5
—
—
—
0
0
21
217
0.97
0.01
1.1
1.1
—
—
—
0
0
30
307
0.98
0.01
1.3
1.2
3.72
3.82
mmol/l
0.36
30
289
10
106
0.94
0.01
1.8
1.2
1.83
2.19
mmol/l
—
10
99
12
114
1.05
0.00
2.8
2.2
7.63
7.87
mmol/l
0.10
12
114
52
514
1.01
0.00
1.6
1.6
5.66
6.64
iu/ml
0.13
14
118
19
189
1.01
0.00
1.3
1.6
991.18
965.03
mu/l
0.04
14
161
39
389
1.00
0.00
1.4
2.4
191.15
202.89
%
0.36
39
368
94
941
1.00
0.00
8.3
11.7
16.25
15.93
%
0.52
88
903
15
147
1.02
0.00
1.0
1.1
—
—
—
0
0
37
373
0.99
0.00
2.0
2.4
51.88
114.35
ug/min
1.13
17
227
43
433
0.99
0.00
1.5
2.2
84.91
90.86
%
0.95
43
425
308
3075
1.00
0.00
4.4
4.0
1.02
1.02
kg/l
0.15
200
2088
6
66
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.52
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
384.00
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
3.6
2.5
0.62
0.60
mmol/l
—
5
57
0
8
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
289.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
68
0.88
-0.00
1.3
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
26.39
—
0
9
7
78
0.90
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXTDISNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISNAS | 1.237 [1.0, 1.53] | 0.05 |
| Birth year | 0.992 [0.98, 1.0] | 0.063 |
During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 1882 females with H8_EXTDISNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISNAS | 0.863 [0.76, 0.98] | 0.02 |
| Birth year | 0.988 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 652 out of 4632 males with H8_EXTDISNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXTDISNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.141% |
| 5 | 0.707% | 1.015% |
| 10 | 1.709% | 2.44% |
| 15 | 3.23% | 4.766% |
| 20 | 5.448% | 8.588% |
Relationships between endpoints
↥Index endpoint: H8_EXTDISNAS – Other specified disorders of external ear
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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