Sleepwalking [somnambulism]

F5_SLEEPWALKING

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F51.3
  • Cause of death: ICD-10 F51.3

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

None

129

6. Filter based on genotype QC (FinnGen only)

118

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 741 345 395
Only index persons 706 334 372
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 24.02 29.30 19.39
Only index persons 24.31 29.66 19.51

-FinnGen-

Key figures

All Female Male
Number of individuals 118 87 31
Unadjusted period prevalence (%) 0.03 0.03 0.01
Median age at first event (years) 33.40 35.04 28.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
122
Matched controls
1220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
174.0
122
*
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
171.5
26.8
27
*
G47.9
ICD-10 Finland
Sleep disorder, unspecified
20.2
21.2
32
21
IEY18
NOMESCO Finland
Psychiatric sleep coaching, individual
98.0
16.0
17
*
N03AE01
ATC
clonazepam; systemic
14.0
14.6
25
22
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
9.7
10.0
20
24
N05AH04
ATC
quetiapine; oral
3.5
9.8
46
178
F51.0
ICD-10 Finland
Nonorganic insomnia
3.3
9.2
50
211
N05AX08
ATC
risperidone; systemic
5.1
8.7
20
45
N06AX11
ATC
mirtazapine; oral
3.1
8.7
62
305
N03AX12
ATC
[U] gabapentin; oral
4.0
8.4
28
85
N06AX16
ATC
venlafaxine; oral
3.6
7.9
32
111
H02AB07
ATC
prednisone; oral
4.1
7.9
24
68
F51.5
ICD-10 Finland
Nightmares
48.1
7.8
9
*
G47.3
ICD-10 Finland
Sleep apnoea
3.4
7.8
34
124
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.8
7.8
19
32
F51.4
ICD-10 Finland
Sleep terrors [night terrors]
85.0
7.5
8
*
N05AA02
ATC
levomepromazine; systemic
12.0
7.5
13
12
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
6.4
7.4
19
34
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
5.0
7.4
17
38
N05BA04
ATC
oxazepam; oral
2.9
7.1
48
224
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.3
6.9
32
120
N05AH03
ATC
olanzapine; systemic
4.1
6.6
20
56
H02AB06
ATC
prednisolone; systemic
2.7
6.6
65
366
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.1
6.5
19
52
P06
ICPC
Sleep disturbance
3.1
6.2
31
121
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.6
6.1
51
263
N06AX26
ATC
vortioxetine; oral
3.8
6.0
20
60

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
74
379
3.42
10.07
2.2
1.9
94.40
97.56
pmol/l
0.24
42
207
24
79
3.54
6.34
1.8
1.5
0.12
0.36
mg/l
—
8
24
60
334
2.57
6.10
5.7
7.4
—
—
—
0
0
28
122
2.68
4.53
1.4
1.2
—
—
—
0
0
61
390
2.13
4.05
10.3
8.2
1.22
1.22
mmol/l
0.07
56
336
50
296
2.17
4.05
7.8
5.8
—
—
—
0
0
43
244
2.18
3.84
3.9
3.7
7.40
7.39
ph
0.24
26
173
17
62
3.02
3.77
1.3
1.2
—
—
—
0
0
79
567
2.12
3.77
7.9
6.9
0.17
0.19
e9/l
0.49
70
503
25
113
2.52
3.73
1.2
1.5
—
—
—
0
0
22
94
2.64
3.67
3.1
2.0
—
—
—
0
0
76
542
2.07
3.63
8.0
6.6
0.50
0.54
e9/l
0.87
67
475
76
542
2.07
3.63
7.9
6.6
0.04
0.04
e9/l
0.39
67
473
12
31
4.18
3.60
1.1
1.2
—
—
—
0
0
102
821
2.48
3.50
4.8
4.4
14.24
14.48
pmol/l
0.67
95
766
78
566
2.05
3.50
7.9
6.5
2.09
2.04
e9/l
0.15
70
509
43
253
2.08
3.45
4.1
2.8
1.02
1.02
kg/l
0.11
27
154
6
7
8.93
3.30
12.5
11.0
0.66
0.61
mmol/l
—
6
7
23
107
2.42
3.22
1.7
1.6
—
—
—
0
0
25
124
2.28
3.03
1.5
1.3
—
—
—
0
0
5
5
10.35
3.00
1.0
1.2
145.60
151.00
nmol/l
—
5
5
73
535
1.91
2.99
6.6
6.0
6.36
6.20
mmol/l
0.29
68
475
60
414
1.88
2.95
1.8
1.9
—
—
—
0
0
37
218
2.00
2.90
3.9
4.0
—
—
—
0
0
22
108
2.27
2.73
1.4
1.5
—
—
—
0
0
13
49
2.85
2.72
3.9
8.9
4.27
7.01
mmol/l
2.40
13
49
24
123
2.18
2.69
1.7
1.6
—
—
—
0
0
79
607
1.86
2.66
11.4
9.0
3.52
4.07
e9/l
2.62
70
532
25
131
2.14
2.65
1.6
1.5
—
—
—
0
0
25
131
2.14
2.65
1.8
1.6
—
—
—
0
0
47
309
1.85
2.63
1.5
1.4
2.17
2.16
g/l
0.02
27
188
67
491
1.81
2.62
9.6
9.8
0.00
0.00
e9/l
0.50
57
398
48
319
1.83
2.58
3.5
2.9
12.22
85.01
e6/l
1.86
37
231
51
347
1.81
2.54
1.5
1.4
1.14
1.02
u/ml
0.12
17
89
55
384
1.79
2.50
4.4
3.7
20.38
29.79
e6/l
0.29
41
246
14
59
2.55
2.39
1.8
1.9
—
—
—
0
0
43
282
1.81
2.39
2.2
2.9
11.07
52.10
ng/l
1.04
24
141
106
914
2.22
2.35
4.8
3.6
5.71
5.60
mmol/l
0.46
100
855
78
612
1.76
2.30
4.4
3.2
67.93
68.71
ug/l
0.02
73
591
24
131
2.04
2.29
1.7
1.5
—
—
—
0
0
24
131
2.04
2.29
1.8
2.9
3.69
4.14
e9/l
0.53
16
122
33
202
1.87
2.27
2.8
2.8
277.38
316.60
umol/l
1.99
26
186
24
132
2.02
2.24
1.7
1.6
—
—
—
0
0
116
1056
3.00
2.22
16.8
12.2
18.87
21.21
mg/l
0.40
98
829
28
164
1.92
2.19
2.6
2.6
5.45
3.31
e6/l
0.27
11
71
36
231
1.79
2.12
2.7
2.1
0.93
0.75
mg/l
0.22
22
166
45
309
1.72
2.10
2.6
7.9
1.01
1.10
inr
1.66
32
256
83
673
1.73
2.08
5.1
4.5
—
49.22
—
0
9
60
449
1.66
2.02
2.6
2.4
—
—
—
0
0
14
65
2.30
1.97
19.1
9.1
—
—
—
0
0
20
109
2.00
1.91
2.7
1.5
—
—
—
0
0
62
474
1.63
1.88
4.0
3.0
6.38
6.27
ph
0.25
34
260
12
53
2.40
1.87
4.2
4.9
24.49
24.40
mmol/l
0.06
12
53
21
118
1.94
1.85
4.0
2.8
3.24
7.53
umol/l
0.85
21
98
36
240
1.71
1.84
10.5
4.1
96.28
94.60
%
0.19
36
235
7
24
3.03
1.75
1.4
1.3
—
—
—
0
0
17
91
2.01
1.71
11.6
8.9
105.35
104.59
mmol/l
0.33
17
91
10
41
2.56
1.69
1.6
5.5
0.65
0.61
%
—
10
41
40
281
1.63
1.66
3.5
2.6
—
—
estimate
—
0
0
40
282
1.62
1.64
3.5
2.8
0.28
0.14
e6/l
0.44
29
195
45
327
1.60
1.63
2.8
3.0
—
0.00
—
0
5
13
64
2.15
1.61
3.9
2.9
52.54
73.39
ng/l
0.81
13
58
103
913
1.82
1.61
3.7
3.3
1.09
1.21
mmol/l
1.17
97
868
25
156
1.76
1.60
2.0
3.3
7.67
28.99
ng/l
1.58
15
82
7
27
2.69
1.54
1.6
2.3
—
—
—
0
0
15
81
1.97
1.48
3.7
4.1
1.11
1.88
mmol/l
0.46
15
66
108
978
1.91
1.47
4.3
3.9
4.52
4.64
mmol/l
0.62
102
937
25
161
1.70
1.43
1.4
1.5
432.00
492.90
titre
—
5
31
108
980
1.89
1.43
4.7
4.2
2.68
2.77
mmol/l
0.45
101
936
19
114
1.79
1.38
5.3
5.7
1.12
1.10
mmol/l
0.10
19
104
31
214
1.60
1.37
3.7
3.6
15.11
78.20
mg/l
1.47
21
143
107
972
1.82
1.35
4.2
3.8
1.47
1.46
mmol/l
0.15
101
929
15
84
1.90
1.34
3.7
4.5
7.39
7.39
ph
—
7
48
70
579
1.49
1.34
4.7
3.5
0.00
0.00
estimate
-0.00
13
123
69
570
1.48
1.32
4.5
3.4
0.00
0.00
estimate
-0.00
14
133
5
18
2.85
1.30
1.0
1.1
—
—
—
0
0
5
19
2.70
1.23
1.2
1.1
—
—
—
0
0
5
19
2.70
1.23
1.4
11.2
65.32
64.66
%
—
5
19
20
127
1.69
1.21
1.3
1.2
—
—
—
0
0
18
111
1.73
1.20
2.6
2.2
319.43
2553.62
u/l
—
7
46
6
26
2.37
1.20
1.8
2.9
37.00
36.91
°c
—
6
26
104
949
1.65
1.14
19.6
15.0
13.36
13.23
%
0.54
104
941
30
215
1.52
1.12
4.0
4.2
6.07
10.60
mg/mmol
0.39
22
143
12
68
1.85
1.05
1.3
1.2
—
—
—
0
0
12
68
1.85
1.05
1.1
1.1
—
—
—
0
0
68
577
1.40
1.04
4.6
3.4
0.00
12.49
estimate
0.50
14
130
13
76
1.80
1.03
1.8
3.6
1.53
1.89
%
—
8
70
15
92
1.72
1.03
2.5
2.0
6.55
6.27
ph
—
10
60
22
152
1.55
0.97
1.5
1.5
—
—
—
0
0
6
27
2.28
0.95
1.0
1.0
—
21.11
—
0
9
6
27
2.28
0.95
2.7
1.9
—
—
—
0
0
49
398
1.39
0.95
2.1
1.9
1.40
1.39
mmol/l
0.00
42
357
30
223
1.46
0.94
1.5
1.6
—
—
—
0
0
30
225
1.44
0.90
1.4
1.3
20.40
29.23
iu/ml
—
5
66
13
80
1.70
0.88
4.2
3.7
0.20
0.61
%
—
5
19
18
123
1.54
0.83
1.1
1.2
—
—
—
0
0
18
124
1.53
0.81
2.8
2.4
—
—
—
0
0
0
26
0.00
0.79
0.0
4.2
—
54.46
—
0
26
41
332
1.35
0.79
4.2
2.2
—
—
—
0
0
34
419
0.74
0.75
2.0
1.7
—
—
—
0
0
14
95
1.54
0.67
1.4
1.4
28.80
20.56
iu/l
—
8
85
5
29
1.75
0.64
1.0
1.2
—
—
—
0
0
15
106
1.47
0.61
1.5
2.0
387.27
404.48
nmol/l
0.19
15
101
0
22
0.00
0.60
0.0
4.1
—
21.32
—
0
14
0
22
0.00
0.60
0.0
4.7
—
3.89
—
0
22
6
35
1.75
0.58
36.3
14.8
0.63
0.69
%
—
6
35
6
35
1.75
0.58
36.3
14.9
1.43
1.37
%
—
6
35
19
143
1.39
0.57
1.3
1.7
3.16
3.42
mmol/l
0.49
14
102
36
300
1.28
0.56
2.6
2.5
—
—
—
0
0
39
329
1.27
0.55
1.9
2.0
—
—
—
0
0
36
302
1.27
0.53
5.1
3.3
0.00
0.00
estimate
-0.00
14
126
16
119
1.40
0.51
1.4
1.4
132.30
124.30
u/ml
—
6
54
7
47
1.52
0.48
1.1
1.3
—
—
—
0
0
45
511
0.81
0.48
4.6
2.9
—
—
estimate
—
0
0
20
157
1.33
0.47
3.5
2.0
2.42
2.41
mmol/l
0.17
20
140
33
278
1.26
0.47
6.6
4.3
—
—
—
0
0
10
69
1.49
0.46
1.7
1.7
—
—
—
0
0
25
204
1.28
0.45
1.4
1.4
40.38
9.61
u/ml
—
8
89
0
15
0.00
0.41
0.0
1.5
—
20.60
—
0
15
0
15
0.00
0.41
0.0
2.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.5
—
18.90
—
0
15
0
16
0.00
0.41
0.0
2.8
—
4.96
—
0
16
0
16
0.00
0.41
0.0
2.8
—
9.38
—
0
16
0
16
0.00
0.41
0.0
2.8
—
2.44
—
0
10
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
36
1.41
0.38
1.8
16.9
—
—
—
0
0
6
41
1.49
0.36
1.2
2.0
—
—
—
0
0
6
41
1.49
0.36
1.2
1.2
—
—
—
0
0
10
73
1.40
0.36
1.3
1.1
—
—
—
0
0
11
82
1.38
0.35
1.2
1.3
—
—
—
0
0
6
45
1.35
0.34
1.3
2.4
—
—
—
0
0
28
241
1.21
0.33
2.8
3.0
—
—
—
0
0
41
369
1.17
0.30
1.8
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
9.29
—
0
10
0
10
0.00
0.21
0.0
1.9
—
0.97
—
0
10
0
12
0.00
0.21
0.0
2.2
—
92.53
—
0
12
0
12
0.00
0.21
0.0
2.2
—
44.53
—
0
12
0
12
0.00
0.21
0.0
2.3
—
1.70
—
0
12
0
14
0.00
0.20
0.0
2.4
—
16.58
—
0
14
17
194
0.86
0.18
1.4
1.6
713.02
963.31
mu/l
0.67
12
166
29
264
1.13
0.17
1.5
1.7
—
—
—
0
0
10
83
1.22
0.16
3.8
1.4
498.30
267.74
mu/l
—
10
76
7
85
0.81
0.15
1.3
1.5
—
—
—
0
0
7
88
0.78
0.15
1.4
1.6
—
—
—
0
0
44
465
0.92
0.14
2.3
2.5
—
—
—
0
0
13
145
0.88
0.10
1.0
1.3
—
—
—
0
0
6
56
1.08
0.09
51.3
11.0
26.33
25.04
mmol/l
—
6
56
45
432
1.07
0.09
4.7
3.0
0.00
0.01
estimate
0.50
12
118
11
99
1.12
0.06
2.6
1.9
—
—
—
0
0
16
149
1.08
0.05
2.4
2.1
—
—
—
0
0
34
348
0.97
0.02
3.4
2.8
0.00
0.00
estimate
-0.00
13
111
8
85
0.94
0.00
1.8
4.1
4.54
4.75
pmol/l
—
8
79
0
9
0.00
-0.00
0.0
1.6
—
11.67
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
486.40
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
89.32
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
77
0.90
-0.00
1.6
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
97
0.92
-0.00
4.7
3.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
32.78
—
0
9
6
62
0.97
-0.00
1.7
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
173.43
—
0
7

Mortality – FinRegistry

Association

Association between endpoint F5_SLEEPWALKING and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPWALKING.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: F5_SLEEPWALKING – Sleepwalking [somnambulism]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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