Other mosquito-borne viral fevers, including avohilmo

AB1_OTHER_MOSQUITO_FEVER_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A92, A93
  • Hospital discharge: ICD-10 A92, A93
  • Hospital discharge: ICD-9 06[6]
  • Hospital discharge: ICD-8 06[7]
  • Cause of death: ICD-10 A92, A93
  • Cause of death: ICD-9 06[6]
  • Cause of death: ICD-8 06[7]

3 out of 7 registries used, show all original rules.

302

4. Check minimum number of events

None

302

5. Include endpoints

None

302

6. Filter based on genotype QC (FinnGen only)

277

Control definitions (FinnGen only)

Control exclude
AB1_ARTHROPOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 277 165 112
Unadjusted period prevalence (%) 0.06 0.06 0.05
Median age at first event (years) 53.85 52.51 55.84

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
283
Matched controls
2830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A92.8
ICD-10 Finland
Other specified mosquito-borne viral fevers
+∞
300.2
232
*
A92.9
ICD-10 Finland
Mosquito-borne viral fever, unspecified
+∞
13.6
13
*
M13.9
ICD-10 Finland
Arthritis, unspecified
3.8
11.4
37
107
A92.0
ICD-10 Finland
Chikungunya virus disease
+∞
9.4
9
*
A93.8
ICD-10 Finland
Other specified arthropod-borne viral fevers
+∞
8.4
8
*
L20
ICPC
Joint symptom/complaint NOS
4.2
7.8
21
53
A92
ICD-10 Finland
Other mosquito-borne viral fevers
+∞
7.3
7
*
M25.5
ICD-10 Finland
Pain in joint
2.0
7.1
117
740
ZYC01, ,
SPAT
2.6
7.0
42
175
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.6
6.4
38
158

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
119
683
2.28
10.09
3.8
3.3
0.00
0.01
estimate
0.80
36
246
100
620
1.95
6.32
1.9
2.7
308.60
332.51
umol/l
1.74
94
561
139
996
1.78
5.32
3.8
3.2
0.00
0.01
estimate
0.50
30
225
91
575
1.86
5.28
4.4
3.3
1.02
1.02
kg/l
0.18
47
377
10
14
7.36
4.69
1.1
1.1
—
—
—
0
0
169
1325
1.68
4.34
3.8
3.4
0.00
0.00
estimate
-0.00
35
246
166
1298
1.67
4.29
3.8
3.4
0.00
0.00
estimate
0.50
37
262
167
1308
1.68
4.28
3.8
3.4
0.00
0.00
estimate
-0.00
36
260
76
492
1.74
3.93
1.4
1.3
5.61
7.80
u/ml
0.19
44
186
79
529
1.68
3.59
1.5
1.3
22.15
26.02
iu/ml
0.13
19
174
83
569
1.65
3.43
4.3
3.3
—
0.00
—
0
5
267
2459
2.52
3.38
14.7
13.8
19.76
21.67
mg/l
0.56
234
1996
135
1050
1.55
3.23
3.5
3.1
6.34
6.18
ph
0.79
77
605
20
87
2.40
3.08
8.9
7.8
—
—
—
0
0
54
346
1.69
2.85
1.9
2.4
162.56
109.28
ug/g
0.39
44
274
9
23
4.01
2.80
1.1
1.1
—
—
—
0
0
219
1931
1.59
2.73
4.2
4.4
14.65
14.45
pmol/l
0.71
213
1811
114
879
1.50
2.72
3.1
3.3
15.40
112.34
ng/l
0.68
64
523
102
769
1.51
2.71
2.8
2.6
54.68
63.21
u/l
0.69
96
729
84
623
1.50
2.37
4.0
4.6
—
—
—
0
0
10
35
2.92
2.23
1.2
1.2
—
—
—
0
0
26
146
1.86
2.15
1.4
1.2
—
—
—
0
0
10
37
2.76
2.09
1.7
1.2
—
—
—
0
0
28
167
1.75
1.92
1.1
1.2
—
—
—
0
0
19
100
1.96
1.90
1.7
2.2
—
—
—
0
0
22
123
1.86
1.86
1.0
1.1
—
0.69
—
0
14
6
151
0.38
1.83
5.5
1.3
—
—
—
0
0
6
151
0.38
1.83
5.5
1.3
—
—
—
0
0
6
152
0.38
1.83
5.5
1.3
—
—
—
0
0
6
153
0.38
1.82
5.5
1.3
—
—
—
0
0
5
137
0.35
1.80
6.4
1.3
—
—
—
0
0
206
1855
1.41
1.77
6.8
8.2
73.53
77.91
u/l
1.01
200
1781
270
2580
2.01
1.71
12.0
11.9
—
—
—
0
0
22
127
1.79
1.70
1.0
1.1
1.52
1.56
g/l
0.27
22
127
33
214
1.61
1.69
1.6
1.9
0.00
0.06
estimate
—
5
51
19
105
1.87
1.67
1.1
1.3
—
—
—
0
0
5
14
3.62
1.62
1.0
1.1
—
—
—
0
0
47
338
1.47
1.53
1.6
2.0
—
—
—
0
0
22
132
1.72
1.51
1.0
1.1
0.90
0.90
g/l
0.03
22
132
5
16
3.16
1.44
1.0
4.3
—
—
—
0
0
6
22
2.76
1.44
1.3
1.6
4.13
4.46
mg/l
—
6
22
53
398
1.41
1.38
1.5
1.4
755.56
445.36
titre
—
9
97
39
277
1.47
1.36
1.8
1.8
—
—
—
0
0
162
1442
1.29
1.30
7.6
10.2
3.95
4.06
e9/l
0.27
150
1259
278
2714
2.38
1.28
21.1
21.3
55.39
40.90
%
0.51
278
2696
278
2714
2.38
1.28
20.9
20.8
30.15
30.30
pg
0.79
278
2699
278
2713
2.40
1.28
20.9
20.9
90.45
90.74
fl
0.56
278
2698
70
558
1.34
1.27
1.7
1.8
0.86
1.20
mg/l
0.87
53
440
18
109
1.70
1.22
1.3
1.2
—
—
—
0
0
0
33
0.00
1.17
0.0
1.1
—
—
—
0
0
243
2301
1.40
1.15
5.2
5.8
38.21
38.70
mmol/mol
0.51
235
2199
278
2717
2.31
1.15
21.1
21.0
137.72
137.06
g/l
0.34
278
2701
201
1857
1.28
1.11
2.5
3.3
37.81
45.76
u/l
1.55
194
1791
64
784
0.76
1.11
2.1
2.4
—
—
—
0
0
7
34
2.09
1.03
1.1
1.2
—
—
—
0
0
18
117
1.58
0.96
3.7
4.8
—
—
—
0
0
6
27
2.25
0.94
1.8
2.3
—
—
—
0
0
78
657
1.26
0.93
1.4
1.3
0.74
1.82
u/ml
1.10
34
205
26
185
1.45
0.93
2.2
2.9
—
—
—
0
0
48
380
1.32
0.92
1.3
1.5
—
—
—
0
0
39
300
1.35
0.91
1.5
1.5
—
—
—
0
0
19
128
1.52
0.88
1.5
2.3
1.32
1.29
%
0.05
19
128
269
2615
1.58
0.88
16.4
17.1
72.62
74.55
umol/l
0.99
269
2597
257
2478
1.40
0.87
4.8
4.8
4.70
4.74
mmol/l
0.23
248
2357
256
2468
1.39
0.86
14.4
15.0
139.87
139.78
mmol/l
0.31
256
2438
27
362
0.72
0.86
3.1
2.6
3.61
2.26
e6/l
0.30
12
159
167
1536
1.21
0.84
4.6
4.0
—
644.82
—
0
22
246
2362
1.32
0.81
4.5
4.5
5.69
5.82
mmol/l
1.41
235
2218
68
797
0.81
0.80
3.4
3.1
8.52
8.32
mmol/l
0.12
61
693
18
123
1.49
0.79
1.6
2.0
0.00
0.02
estimate
—
7
42
240
2299
1.29
0.79
5.1
5.3
1.75
1.83
mu/l
0.63
233
2174
0
26
0.00
0.79
0.0
1.5
—
1.47
—
0
19
86
747
1.22
0.77
4.1
6.2
—
—
—
0
0
41
504
0.78
0.73
1.6
1.7
—
—
—
0
0
38
302
1.30
0.73
1.2
1.5
—
—
—
0
0
5
26
1.94
0.71
1.0
1.2
—
—
—
0
0
7
42
1.68
0.69
7.1
5.8
10.14
10.76
mmol/l
—
7
37
18
128
1.43
0.67
5.7
7.9
24.37
24.63
mmol/l
0.16
18
121
86
757
1.20
0.67
2.6
2.9
0.00
0.02
estimate
0.99
31
210
7
43
1.64
0.67
7.1
5.7
107.71
105.16
mmol/l
—
7
38
11
166
0.65
0.66
2.6
3.8
53.81
84.65
ng/l
1.53
11
146
10
154
0.64
0.66
5.7
2.4
53.80
51.90
u/ml
—
10
148
255
2474
1.31
0.65
14.6
15.1
3.95
3.95
mmol/l
0.11
255
2437
6
101
0.59
0.63
5.5
1.6
—
—
—
0
0
6
103
0.57
0.63
1.0
2.9
—
—
—
0
0
73
830
0.84
0.62
6.8
6.2
—
—
—
0
0
244
2358
1.25
0.62
4.2
4.1
1.30
1.29
mmol/l
0.04
236
2218
51
430
1.23
0.61
1.6
1.7
431.48
447.31
pmol/l
0.20
42
382
5
30
1.68
0.61
1.8
1.6
99.30
20.23
ng/l
—
5
30
5
30
1.68
0.61
1.4
2.7
—
—
—
0
0
63
723
0.83
0.60
3.3
4.0
3.55
8.98
mg/mmol
1.43
42
458
0
22
0.00
0.59
0.0
12.6
—
1009.41
—
0
22
0
22
0.00
0.59
0.0
3.1
—
42.84
—
0
9
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
173.01
—
0
22
0
22
0.00
0.59
0.0
2.8
—
22.24
—
0
14
254
2470
1.28
0.57
4.8
4.7
1.45
1.46
mmol/l
0.17
246
2338
143
1328
1.16
0.56
5.5
6.3
1.92
1.89
e9/l
0.17
133
1178
18
133
1.38
0.56
1.6
2.1
—
—
—
0
0
13
182
0.70
0.56
1.7
8.1
7.88
8.43
mmol/l
0.11
13
177
17
125
1.38
0.55
1.6
2.3
0.65
0.60
%
0.30
17
125
257
2507
1.27
0.52
5.3
5.3
2.79
2.82
mmol/l
0.20
247
2379
41
346
1.22
0.50
1.4
1.4
—
—
—
0
0
25
200
1.27
0.48
2.6
2.4
6.68
14.63
au/ml
—
6
11
14
102
1.39
0.48
1.6
1.4
1.06
1.20
g/l
0.67
14
97
7
47
1.50
0.48
1.3
1.3
—
—
—
0
0
139
1301
1.13
0.47
5.5
6.2
0.55
0.56
e9/l
0.16
127
1125
5
82
0.60
0.46
1.6
1.5
—
—
—
0
0
139
1302
1.13
0.46
5.6
6.3
0.04
0.04
e9/l
0.15
127
1123
5
85
0.58
0.46
1.6
1.6
—
—
—
0
0
68
608
1.16
0.44
4.2
4.1
—
—
—
0
0
66
589
1.16
0.44
1.6
1.4
2.02
2.29
g/l
1.16
54
381
26
212
1.25
0.44
5.1
8.7
125.31
122.88
g/l
0.25
26
207
40
343
1.19
0.43
2.2
2.4
2.34
2.35
g/l
0.02
40
312
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
2.02
—
0
16
0
16
0.00
0.41
0.0
3.9
—
17.28
—
0
16
64
711
0.87
0.41
3.1
3.3
31.54
52.71
mg/l
0.61
42
466
15
193
0.76
0.40
4.4
8.1
—
—
—
0
0
8
60
1.34
0.40
1.1
2.9
7.44
7.42
ph
—
8
60
124
1161
1.12
0.40
2.6
2.9
—
—
—
0
0
38
327
1.19
0.40
1.4
1.6
1217.84
1189.46
nmol/l
0.07
31
254
25
206
1.23
0.39
4.9
4.7
0.00
0.19
%
—
6
53
78
711
1.13
0.39
2.7
3.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
71.37
—
0
19
27
321
0.82
0.38
1.4
1.2
—
—
—
0
0
5
36
1.40
0.38
1.0
1.1
—
—
—
0
0
6
41
1.47
0.36
2.3
3.1
3.99
4.88
e9/l
—
6
41
5
77
0.64
0.36
1.4
1.3
—
—
—
0
0
17
136
1.27
0.34
1.9
1.9
4.00
5.15
iu/ml
—
6
28
24
201
1.21
0.33
5.8
4.4
0.00
0.68
%
—
6
60
143
1361
1.10
0.33
5.5
6.6
0.19
0.19
e9/l
0.02
135
1196
32
367
0.86
0.32
1.3
1.7
—
—
—
0
0
26
221
1.19
0.32
5.0
8.5
97.17
95.32
%
1.92
26
214
120
1136
1.10
0.30
8.3
10.3
0.00
0.00
e9/l
0.27
104
916
15
184
0.80
0.29
1.0
1.1
—
—
—
0
0
69
640
1.10
0.26
2.9
2.6
—
—
—
0
0
81
758
1.10
0.26
3.2
2.9
30.16
145.64
e6/l
0.71
64
571
35
312
1.14
0.25
1.5
1.4
—
—
—
0
0
31
349
0.87
0.25
1.8
2.0
—
—
—
0
0
9
75
1.21
0.25
1.0
1.1
—
—
—
0
0
22
189
1.18
0.25
1.7
2.8
4.12
4.74
kpa
1.22
22
184
6
81
0.74
0.24
1.0
3.1
25.23
25.06
mmol/l
—
6
76
23
199
1.17
0.24
5.2
4.4
0.00
0.17
%
—
5
54
73
683
1.09
0.23
5.4
4.9
1.83
1.76
ug/l
0.12
68
619
0
11
0.00
0.21
0.0
2.1
—
2.07
—
0
11
0
11
0.00
0.21
0.0
2.1
—
4.69
—
0
11
0
11
0.00
0.21
0.0
2.3
—
0.91
—
0
11
0
11
0.00
0.21
0.0
1.1
—
177.88
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
105
0.76
0.21
1.8
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.17
0.21
1.0
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
28.38
—
0
13
0
13
0.00
0.21
0.0
1.1
—
72.53
—
0
13
0
14
0.00
0.20
0.0
1.3
—
100.75
—
0
8
118
1133
1.07
0.20
2.7
2.8
—
—
estimate
—
0
0
70
659
1.08
0.20
3.1
2.7
0.12
0.32
e6/l
3.02
53
469
24
213
1.14
0.19
5.1
4.3
0.00
0.88
%
—
5
70
7
63
1.11
0.17
9.9
5.7
1.17
1.17
mmol/l
—
7
55
12
101
1.20
0.17
1.3
1.7
—
—
—
0
0
8
68
1.18
0.16
2.3
2.6
—
—
—
0
0
26
235
1.12
0.16
5.3
8.3
1.85
0.85
mmol/l
1.30
18
200
8
71
1.13
0.16
1.1
1.2
—
—
—
0
0
25
230
1.10
0.12
1.1
1.2
—
—
—
0
0
11
95
1.16
0.12
1.3
1.8
1.66
1.51
g/l
0.25
11
85
44
416
1.07
0.11
3.1
2.9
0.71
0.72
ug/l
0.02
23
238
11
125
0.88
0.10
2.5
3.1
24.99
24.18
mmol/l
0.75
11
125
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
31
292
1.07
0.09
1.2
1.4
—
—
—
0
0
104
1016
1.04
0.08
2.0
2.0
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
92
897
1.04
0.08
3.4
3.5
10.02
103.14
e6/l
1.52
69
608
26
244
1.07
0.08
5.2
7.9
5.22
5.10
kpa
0.46
26
235
26
244
1.07
0.08
5.2
7.9
13.32
12.26
kpa
0.34
26
236
19
205
0.92
0.08
1.6
1.4
—
—
—
0
0
98
1003
0.96
0.08
2.0
2.0
91.40
95.73
pmol/l
0.57
58
544
9
87
1.04
0.07
5.8
4.9
1.01
0.86
%
—
9
80
17
183
0.92
0.06
1.2
1.8
—
—
—
0
0
110
1119
0.97
0.06
4.6
7.1
1.22
1.21
mmol/l
0.30
94
980
71
693
1.03
0.06
3.0
4.0
7.41
7.39
ph
1.28
47
490
76
744
1.03
0.05
1.5
1.5
—
—
—
0
0
81
794
1.03
0.05
2.8
3.4
2.33
2.35
mmol/l
1.09
76
724
101
995
1.02
0.04
24.4
9.8
1.35
1.15
inr
2.50
88
811
25
240
1.05
0.03
5.5
8.2
7.41
7.42
ph
0.56
17
126
16
151
1.06
0.03
1.1
1.1
—
—
—
0
0
138
1367
1.02
0.03
4.0
4.8
6.32
6.54
mmol/l
0.78
132
1293
21
219
0.96
0.03
1.0
1.3
65.92
112.55
u/ml
0.42
12
94
20
207
0.96
0.01
2.0
3.5
2.43
1.70
mmol/l
1.03
20
173
27
277
0.97
0.01
1.9
1.8
3.86
3.52
mmol/l
1.00
22
201
34
333
1.02
0.01
1.4
1.2
—
—
—
0
0
10
94
1.07
0.01
1.5
1.3
—
3.55
—
0
11
13
124
1.05
0.00
8.4
8.0
15.66
15.81
%
0.10
13
119
21
204
1.03
0.00
2.9
2.1
6.17
6.11
ph
0.14
15
123
22
218
1.01
0.00
1.8
2.5
12.75
14.56
nmol/l
0.74
22
208
23
231
1.00
0.00
1.2
1.6
—
—
—
0
0
45
449
1.00
0.00
3.6
3.6
730.68
278.24
ng/l
0.29
28
313
61
609
1.00
0.00
1.8
2.1
—
—
—
0
0
22
216
1.02
0.00
1.9
3.5
5.49
5.69
kpa
0.46
22
210
19
186
1.02
0.00
2.2
2.8
68.25
72.87
e9/l
0.19
12
127
21
214
0.98
0.00
2.4
3.5
7.42
7.39
ph
—
10
121
72
715
1.01
0.00
1.8
2.1
191.99
206.20
u/l
0.07
67
688
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
13.53
—
0
7
0
7
0.00
0.00
0.0
1.0
—
5.66
—
0
7
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
12.24
—
0
9
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.6
—
54.93
—
0
7
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
97
0.93
-0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
2.4
2.2
69.44
63.33
%
—
5
57
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
51
0.98
-0.00
1.6
5.3
—
—
—
0
0
6
59
1.02
-0.00
2.3
2.9
56.83
60.49
%
—
6
59
9
98
0.92
-0.00
5.9
4.6
1.72
1.57
%
—
9
91
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.42
—
0
6
0
5
0.00
-0.00
0.0
2.8
—
2.20
—
0
5
109
1090
1.00
-0.00
1.6
1.9
1.47
1.38
mmol/l
0.48
99
953
6
65
0.92
-0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
8
0.00
-0.00
0.0
4.1
—
8.20
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_OTHER_MOSQUITO_FEVER_WIDE – Other mosquito-borne viral fevers, including avohilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).