Other mosquito-borne viral fevers

AB1_OTHER_MOSQUITO_FEVER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A92, A93
  • Hospital discharge: ICD-9 06[6]
  • Hospital discharge: ICD-8 06[7]
  • Cause of death: ICD-10 A92, A93
  • Cause of death: ICD-9 06[6]
  • Cause of death: ICD-8 06[7]

2 out of 7 registries used, show all original rules.

87

4. Check minimum number of events

None

87

5. Include endpoints

None

87

6. Filter based on genotype QC (FinnGen only)

78

Control definitions (FinnGen only)

Control exclude
AB1_ARTHROPOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 699 362 335
Only index persons 635 339 296
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 46.07 48.04 43.79
Only index persons 45.47 47.71 42.91

-FinnGen-

Key figures

All Female Male
Number of individuals 78 42 36
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 50.72 49.82 51.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
81
Matched controls
810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A92.8
ICD-10 Finland
Other specified mosquito-borne viral fevers
+∞
65.9
54
*
M13.9
ICD-10 Finland
Arthritis, unspecified
7.1
7.5
18
31
A92.0
ICD-10 Finland
Chikungunya virus disease
+∞
7.4
7
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
9
10
9.95
4.92
1.8
1.3
—
—
—
0
0
26
134
2.38
3.05
1.5
1.3
1.55
9.04
u/ml
1.36
11
54
29
169
2.12
2.49
4.3
5.7
—
—
—
0
0
6
12
5.30
2.45
1.2
1.2
—
—
—
0
0
45
311
2.01
2.41
8.6
12.1
0.00
0.00
e9/l
0.50
40
250
34
217
1.98
2.25
2.9
3.7
0.00
0.00
estimate
-0.00
14
63
6
14
4.54
2.19
2.5
1.3
13859.00
14536.75
e6/l
—
6
8
53
400
1.94
2.08
3.4
3.6
0.00
0.00
estimate
-0.00
15
72
53
400
1.94
2.08
3.4
3.7
0.00
0.00
estimate
-0.00
15
68
8
26
3.30
2.07
1.3
1.3
—
—
—
0
0
11
45
2.67
2.03
1.4
1.2
—
16.30
—
0
5
19
101
2.15
2.02
1.5
1.6
1119.51
1210.48
nmol/l
0.15
14
80
5
11
4.76
1.97
1.4
1.2
—
—
—
0
0
25
150
1.96
1.93
1.5
1.3
8.55
44.98
iu/ml
—
6
50
53
406
1.88
1.92
3.4
3.7
0.00
0.00
estimate
-0.00
15
63
26
159
1.94
1.90
1.4
1.8
1.21
1.52
mg/l
0.24
21
131
60
486
1.90
1.74
3.7
4.0
—
—
—
0
0
42
306
1.77
1.73
3.3
3.7
0.00
0.00
estimate
-0.00
13
61
13
64
2.23
1.65
1.1
1.7
—
—
—
0
0
12
57
2.30
1.64
2.8
3.6
—
—
—
0
0
26
168
1.81
1.58
1.5
1.4
2.44
2.33
g/l
0.20
19
105
0
43
0.00
1.57
0.0
1.3
—
0.41
—
0
15
40
294
1.71
1.56
2.4
3.2
—
—
—
0
0
33
230
1.73
1.55
2.5
3.2
0.00
0.00
estimate
-0.00
13
53
29
197
1.74
1.48
2.2
2.8
0.05
0.27
e6/l
2.45
22
142
25
164
1.76
1.43
1.6
2.2
—
—
—
0
0
6
23
2.73
1.39
1.7
2.3
12.08
11.33
mg/l
—
6
23
10
48
2.24
1.34
1.7
3.3
—
—
—
0
0
36
267
1.63
1.30
2.5
4.2
21.19
257.29
ng/l
0.54
19
180
45
355
1.60
1.25
6.9
5.6
30.53
27.63
%
1.06
45
339
42
326
1.60
1.24
3.3
3.4
6.39
6.14
ph
0.68
23
185
28
197
1.64
1.23
3.1
4.5
—
—
—
0
0
31
224
1.62
1.23
3.0
3.8
—
—
—
0
0
12
65
1.99
1.21
2.3
1.8
9.33
10.27
g/l
0.36
12
59
8
40
2.11
1.16
2.0
2.5
—
—
—
0
0
31
227
1.59
1.15
7.9
5.8
—
—
—
0
0
26
183
1.62
1.13
1.5
1.3
0.72
2.53
u/ml
1.37
13
52
7
32
2.30
1.11
1.3
1.3
0.18
0.23
g/l
—
7
32
13
75
1.87
1.10
1.5
2.3
323.77
395.90
nmol/l
0.79
13
69
7
33
2.22
1.08
1.3
1.3
1.04
1.19
g/l
—
7
33
44
355
1.52
1.04
5.2
5.5
54.99
57.66
%
0.90
44
336
12
69
1.87
1.03
1.5
1.2
—
—
—
0
0
7
36
2.03
0.99
1.0
1.1
—
—
—
0
0
68
610
1.72
0.96
13.2
18.1
13.60
13.62
%
0.03
68
605
8
42
2.00
0.92
1.3
1.3
—
—
—
0
0
34
266
1.48
0.90
2.9
3.5
15.33
38.14
e6/l
0.71
26
186
18
122
1.61
0.90
2.8
3.7
122.08
312.79
ng/l
0.33
12
90
8
44
1.91
0.89
1.4
1.1
—
—
—
0
0
6
30
2.08
0.89
1.0
1.2
0.88
0.87
g/l
—
6
30
6
30
2.08
0.89
1.0
1.2
1.38
1.60
g/l
—
6
30
14
89
1.69
0.88
1.4
1.2
—
—
—
0
0
30
233
1.46
0.81
2.4
2.9
10.42
59.13
e6/l
1.50
24
181
53
458
1.45
0.81
3.3
4.1
—
21.71
—
0
7
16
108
1.60
0.81
1.1
1.7
—
—
—
0
0
42
348
1.43
0.81
6.9
5.7
3.04
2.79
%
0.34
42
328
6
33
1.88
0.81
1.0
1.2
—
—
—
0
0
41
346
1.37
0.68
7.1
5.7
0.67
0.62
%
0.30
41
323
14
96
1.55
0.67
1.1
1.4
—
—
—
0
0
16
216
0.68
0.65
3.1
3.4
26.03
61.54
mg/l
—
10
137
12
80
1.59
0.64
1.1
1.5
—
—
—
0
0
20
150
1.44
0.64
2.5
2.9
0.72
0.76
ug/l
0.11
12
93
36
300
1.36
0.63
2.2
2.0
—
—
—
0
0
0
20
0.00
0.61
0.0
1.4
—
—
—
0
0
17
220
0.71
0.54
3.4
4.2
2.77
10.94
mg/mmol
1.84
12
136
13
96
1.42
0.45
1.0
1.6
—
—
—
0
0
14
105
1.40
0.45
1.9
2.5
2.51
2.31
g/l
0.49
14
94
38
332
1.27
0.44
2.3
2.6
—
—
estimate
—
0
0
8
59
1.39
0.42
3.9
7.1
1.24
1.31
mmol/l
—
8
59
44
393
1.26
0.42
3.8
7.4
9.46
10.96
umol/l
0.77
44
375
8
60
1.37
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
59.53
—
0
15
0
15
0.00
0.41
0.0
3.8
—
13.14
—
0
15
0
15
0.00
0.41
0.0
1.9
—
36.67
—
0
15
0
17
0.00
0.41
0.0
2.9
—
4.76
—
0
8
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
73
699
1.45
0.40
16.2
15.7
23.87
25.11
mg/l
0.13
67
581
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
5
35
1.46
0.40
1.8
4.8
36.94
37.03
°c
—
5
35
0
19
0.00
0.39
0.0
3.0
—
62.57
—
0
19
9
68
1.36
0.39
1.9
1.9
—
0.00
estimate
—
0
11
10
73
1.42
0.36
1.2
1.8
—
—
—
0
0
27
232
1.25
0.35
4.9
6.2
—
—
—
0
0
6
45
1.36
0.34
1.0
1.0
—
—
—
0
0
74
714
1.42
0.33
14.4
17.1
139.86
139.77
mmol/l
0.14
74
708
74
714
1.42
0.33
14.6
17.1
4.00
3.96
mmol/l
0.78
74
705
35
312
1.21
0.32
17.9
9.7
1.26
1.16
inr
0.44
30
249
11
140
0.75
0.31
2.2
3.0
2.45
2.45
mmol/l
0.03
11
125
21
179
1.23
0.29
3.8
3.6
1.02
1.02
kg/l
0.33
14
110
5
74
0.65
0.27
2.0
1.5
—
—
—
0
0
11
87
1.31
0.26
1.6
2.0
—
—
—
0
0
10
78
1.32
0.25
2.3
3.0
1.90
1.87
%
—
10
68
12
97
1.28
0.24
2.0
1.2
—
—
—
0
0
17
144
1.23
0.24
1.5
1.7
—
—
—
0
0
5
39
1.30
0.23
2.2
2.0
—
—
—
0
0
76
769
0.81
0.22
24.0
23.0
29.91
30.36
pg
1.33
76
764
76
769
0.81
0.22
24.2
23.2
134.22
136.28
g/l
0.64
76
764
76
769
0.81
0.22
24.1
23.0
4.52
4.52
e12/l
0.03
76
753
76
769
0.81
0.22
24.0
23.0
90.09
91.08
fl
1.11
76
764
76
769
0.81
0.22
24.1
23.5
40.48
40.54
%
0.05
76
763
14
117
1.24
0.22
1.2
1.9
—
—
—
0
0
76
768
0.83
0.22
24.1
23.1
250.00
250.51
e9/l
0.02
76
757
0
10
0.00
0.21
0.0
2.2
—
10.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
182.10
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
23
204
1.18
0.21
1.6
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.81
—
0
8
0
13
0.00
0.21
0.0
1.1
—
1.78
—
0
7
6
49
1.24
0.20
1.7
2.7
1.42
1.46
%
—
6
49
28
306
0.87
0.18
4.9
6.4
1.21
1.21
mmol/l
0.09
28
286
65
671
0.84
0.18
4.9
6.4
37.46
39.33
mmol/mol
1.28
59
634
75
731
1.35
0.16
13.8
13.1
—
—
—
0
0
70
717
0.83
0.15
4.8
5.5
2.97
2.76
mmol/l
1.42
64
674
25
230
1.13
0.13
1.6
2.4
—
—
—
0
0
5
44
1.15
0.10
1.0
3.4
7.44
7.42
ph
—
5
38
10
87
1.17
0.10
1.3
1.5
—
—
—
0
0
5
46
1.09
0.10
1.0
1.9
—
—
—
0
0
5
46
1.09
0.10
1.0
3.3
5.10
5.14
kpa
—
5
46
5
47
1.07
0.09
1.8
2.7
0.74
0.65
%
—
5
47
5
64
0.77
0.08
2.6
2.2
4.34
3.59
mmol/l
—
5
47
5
64
0.77
0.08
5.2
7.8
—
—
—
0
0
8
76
1.06
0.07
1.5
1.4
—
—
—
0
0
32
308
1.06
0.05
1.7
2.0
89.44
92.22
pmol/l
0.15
16
169
36
349
1.06
0.04
4.6
7.5
1.22
1.21
mmol/l
0.47
30
308
21
201
1.06
0.03
2.1
2.9
—
—
—
0
0
69
682
1.08
0.03
3.7
4.1
1.20
1.28
mmol/l
0.61
64
631
71
703
1.08
0.02
4.2
4.9
4.80
4.68
mmol/l
0.49
65
661
22
213
1.05
0.01
3.0
4.1
7.41
7.40
ph
0.66
16
151
11
115
0.95
0.00
1.6
3.6
0.81
0.81
mmol/l
0.07
11
107
70
701
0.99
0.00
4.5
4.8
1.43
1.46
mmol/l
0.24
65
653
69
689
1.01
0.00
4.2
4.6
5.65
5.93
mmol/l
1.66
64
641
0
5
0.00
-0.00
0.0
10.6
—
0.69
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1779.00
—
0
5
0
6
0.00
-0.00
0.0
11.7
—
1066.50
—
0
6
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
10.34
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
8.94
—
0
5
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
72
0.97
-0.00
1.6
3.7
2.07
1.87
mmol/l
—
7
60
0
5
0.00
-0.00
0.0
4.4
—
51.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
1.69
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.7
—
6.97
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.1
—
3.57
—
0
7
0
6
0.00
-0.00
0.0
15.3
—
1792.00
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
42.00
—
0
7

Mortality – FinRegistry

Association

Association between endpoint AB1_OTHER_MOSQUITO_FEVER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_OTHER_MOSQUITO_FEVER.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_OTHER_MOSQUITO_FEVER – Other mosquito-borne viral fevers

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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