Frontotemporal dementia

FTD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F020&G310
  • Cause of death: ICD-10 F020&G310

2 out of 7 registries used, show all original rules.

231

4. Check minimum number of events

None

231

5. Include endpoints

None

231

6. Filter based on genotype QC (FinnGen only)

202

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 202 90 112
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 69.31 69.41 69.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
208
Matched controls
2080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
211.1
165
*
G31.0
ICD-10 Finland
Circumscribed brain atrophy
2384.2
129.6
112
*
F03
ICD-10 Finland
Unspecified dementia
89.4
124.6
67
11
N05AX08
ATC
risperidone; systemic
21.4
91.4
80
59
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
15.5
83.2
93
103
N05AH03
ATC
olanzapine; systemic
21.5
78.7
66
44
XA800
NOMESCO Finland
Neuropsychological investigation
24.8
70.7
54
29
TAB00
NOMESCO Finland
Lumbar puncture
18.3
67.7
61
46
N03AG01
ATC
valproic acid; systemic, rectal
18.3
64.9
58
43
Z2445
NOMESCO Finland
Psychologist
26.8
59.3
43
20
N05AH04
ATC
quetiapine; oral
9.5
56.1
92
161
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
13.2
50.0
54
54
P20
ICPC
Memory disturbance
8.1
45.7
82
155
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
9.0
45.1
69
109
P70
ICPC
Dementia
190.1
44.8
45
*
N06DX01
ATC
memantine; oral
111.9
35.0
37
*
ZY010
NOMESCO Finland
Hospital outpatient
13.4
34.5
35
31
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
9.5
33.2
44
57
N05BA06
ATC
lorazepam; systemic, sublingual
9.6
31.4
41
52
N06DA02
ATC
donepezil; oral
67.3
30.2
34
6
F02.09
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
29.9
28
*
F06.7
ICD-10 Finland
Mild cognitive disorder
11.3
29.3
33
34
A28
ICPC
Limited function/disability NOS
5.0
28.4
91
280
N06DA03
ATC
rivastigmine; oral, transdermal
295.5
26.3
26
*
N05BA04
ATC
oxazepam; oral
4.1
22.1
91
329
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
8.5
20.9
29
39
R41.3
ICD-10 Finland
Other amnesia
9.4
20.6
26
31
F0203, G310,
ICD-10 Finland
+∞
20.1
19
*
F0200, G310,
ICD-10 Finland
+∞
19.0
18
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
7.5
18.4
28
42
F0204, G310,
ICD-10 Finland
+∞
18.0
17
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
18.0
17
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
6.0
17.4
34
66
N06AX11
ATC
mirtazapine; oral
3.4
17.2
101
447
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
23.3
16.4
23
11
G30.1
ICD-10 Finland
Alzheimer disease with late onset
52.0
16.3
19
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
14.7
15.7
26
20
SPAT1245
SPAT
Provision of support and information to patient’s family members
7.7
15.6
23
33
IGY02
NOMESCO Finland
Psychiatric monitoring contact
18.3
15.2
23
14
N06AB10
ATC
escitalopram; oral
3.8
14.8
57
190
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
+∞
14.8
14
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
+∞
14.8
14
*
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
39.2
14.7
18
5
AA1AD
NOMESCO Finland
CT of head and brain
3.1
14.7
102
489
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.3
14.6
32
69
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.7
14.2
24
40
SPAT1234
SPAT
Support of social functional capacity
6.3
14.0
25
44
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
149.3
13.6
14
*
R41.0
ICD-10 Finland
Disorientation, unspecified
6.9
13.6
22
35
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.8
13.3
26
50
SPAT1216
SPAT
Assessment of functional ability
3.4
12.8
56
202
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
138.0
12.6
13
*
Z2446
NOMESCO Finland
Social worker
4.9
12.4
29
66
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.8
12.3
24
46
ZY000
NOMESCO Finland
Hospital inpatient
28.7
12.2
16
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
11.8
68
287
IGY99
NOMESCO Finland
Other psychiatric treatment contact
69.0
11.7
13
*
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.2
11.7
34
92
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
126.7
11.5
12
*
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
126.7
11.5
12
*
A04
ICPC
Weakness/tiredness general
3.3
11.1
50
182
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
16.7
11.0
17
11
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.0
10.7
33
93
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
15.3
10.7
17
12
N05AX12
ATC
aripiprazole; systemic
13.0
10.6
18
15
F29
ICD-10 Finland
Unspecified nonorganic psychosis
11.5
10.5
19
18
F0201, G310,
ICD-10 Finland
+∞
10.5
10
*
F02.00
ICD-10 Finland
Dementia in Pick's disease without additional symptoms
+∞
10.5
10
*
RT250, ,
NOMESCO Finland
+∞
10.5
10
*
G30.8
ICD-10 Finland
Other Alzheimer disease
+∞
10.5
10
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
10.5
10
*
F0202, G310,
ICD-10 Finland
+∞
10.5
10
*
F05.9
ICD-10 Finland
Delirium, unspecified
12.2
10.3
18
16
N99
ICPC
Neurological disease other
27.6
9.9
13
5
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
57.8
9.7
11
*
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
9.4
9.5
19
22
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
31.7
9.5
12
*
F22.0
ICD-10 Finland
Delusional disorder
23.0
9.5
13
6
F06.4
ICD-10 Finland
Organic anxiety disorder
+∞
9.4
9
*
RT150, ,
NOMESCO Finland
+∞
9.4
9
*
N05AD01
ATC
haloperidol; systemic
8.4
9.4
20
26
Z2221
NOMESCO Finland
Medical doctor
2.6
9.3
74
364
N06AX26
ATC
vortioxetine; oral
5.0
9.0
20
43
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.3
8.7
15
13
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
13.5
8.5
14
11
N05CD07
ATC
temazepam; oral
3.0
8.4
42
161
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
8.4
8
*
N06AB04
ATC
citalopram; systemic
2.6
8.2
58
267
N06AX16
ATC
venlafaxine; oral
3.0
7.9
39
148
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
7.7
94
552
SPAT1053
SPAT
Memory test
2.8
7.6
45
189
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
82.9
7.5
8
*
-, ,
ICD-10 Finland
8.9
7.5
15
18
SPAT1101
SPAT
Orthostatic test
4.4
7.4
19
46
P99
ICPC
Psychological disorders other
9.9
7.4
14
15
N05AN01
ATC
lithium; oral
11.5
7.4
13
12
S01.0
ICD-10 Finland
Open wound of scalp
3.3
7.4
29
96
F064, G310,
ICD-10 Finland
+∞
7.3
7
*
L28
ICPC
Limited function/disability (L)
2.5
7.3
57
274
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
31.2
7.2
9
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.1
7.2
20
52
P29
ICPC
Psychological sympt/compl other
4.7
7.1
17
39
N03AX09
ATC
lamotrigine; oral
6.5
6.9
17
28
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.2
6.9
11
432
N05BA01
ATC
diazepam; systemic, rectal
2.7
6.8
41
173
Z3226
NOMESCO Finland
Physiotherapist
2.5
6.8
52
247
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
41.4
6.8
8
*
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
41.4
6.8
8
*
P28
ICPC
Limited function/disability (P)
41.4
6.8
8
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.9
6.8
18
33
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
8.3
6.7
14
18
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
23.4
6.7
9
*
Z3231
NOMESCO Finland
Registered nurse
2.2
6.5
74
417
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
6.5
84
498
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
14.9
6.5
10
7
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
72.0
6.5
7
*
N06DA04
ATC
galantamine; oral
72.0
6.5
7
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
11.5
6.4
11
10
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
11.5
6.4
11
10
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
5.4
6.4
18
36
F02.01
ICD-10 Finland
Dementia in Pick's disease has other additional symptoms, mainly paranoidism
+∞
6.3
6
*
F060, G310,
ICD-10 Finland
+∞
6.3
6
*
F01.9
ICD-10 Finland
Vascular dementia, unspecified
+∞
6.3
6
*
F020, G310,
ICD-10 Finland
+∞
6.3
6
*
F02.04
ICD-10 Finland
Dementia in Pick's disease other additional symptoms of mixed type
+∞
6.3
6
*
IGV01
NOMESCO Finland
Psychiatric network contact
27.6
6.3
8
*
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
8.1
6.2
13
17
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.7
6.2
20
58
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
9.0
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
37
14.39
43.48
1.1
1.2
2.07
21.86
e6/l
0.53
30
28
42
39
13.24
40.42
1.1
1.3
143.57
97.77
e6/l
0.20
30
30
27
34
8.98
20.51
1.1
1.3
—
—
—
0
0
86
328
3.77
18.81
2.0
1.7
1304.66
1177.80
nmol/l
0.63
67
248
21
16
14.45
12.74
1.3
1.1
—
—
—
0
0
44
176
2.90
8.17
2.7
2.6
36.95
35.17
u/l
0.09
39
141
128
854
2.30
7.71
3.0
2.1
92.10
97.17
pmol/l
0.71
71
438
107
664
2.26
7.67
2.6
3.6
2.36
2.35
mmol/l
0.18
90
601
15
18
8.89
7.46
1.0
1.1
—
—
—
0
0
76
414
2.32
7.39
3.3
3.3
2.46
2.46
mmol/l
0.20
61
370
22
577
0.31
6.90
3.0
3.8
—
—
—
0
0
77
437
2.21
6.67
4.4
4.0
—
0.33
—
0
6
81
478
2.14
6.29
4.1
4.1
84.12
86.57
%
0.34
76
473
17
44
4.12
6.12
1.0
1.3
—
—
—
0
0
97
626
2.03
5.83
4.0
4.3
7.40
7.39
ph
1.68
69
454
60
331
2.14
5.43
3.2
3.4
6.42
2.65
e6/l
0.60
24
171
89
578
1.94
5.08
2.0
1.7
18.38
21.54
nmol/l
1.36
81
479
122
905
1.84
4.41
7.8
6.4
1.20
1.21
mmol/l
0.31
109
829
26
524
0.42
4.20
4.3
3.9
0.00
0.01
estimate
0.50
12
178
0
102
0.00
4.16
0.0
4.2
—
1.60
—
0
96
86
584
1.81
4.07
4.0
3.6
0.23
0.57
e6/l
1.60
64
432
115
856
1.77
3.94
4.5
5.1
35.33
35.07
g/l
0.20
100
807
84
581
1.75
3.65
4.1
3.4
—
—
—
0
0
0
90
0.00
3.59
0.0
4.5
—
0.86
—
0
83
46
719
0.54
3.42
3.4
4.3
6.16
9.67
mg/mmol
0.82
33
461
8
14
5.89
3.37
1.4
1.1
—
—
—
0
0
8
14
5.89
3.37
1.4
1.1
—
—
—
0
0
49
745
0.55
3.28
1.8
2.0
1.64
1.31
mmol/l
1.89
43
596
8
15
5.50
3.22
1.4
1.1
—
—
—
0
0
8
15
5.50
3.22
1.4
1.1
—
—
—
0
0
8
15
5.50
3.22
1.4
1.1
—
—
—
0
0
86
618
1.67
3.15
2.6
2.1
477.16
222.28
u/l
0.94
77
581
15
56
2.81
3.13
4.2
3.8
2.00
2.11
index
—
8
36
80
565
1.68
3.13
7.6
6.5
—
—
—
0
0
6
8
7.68
3.07
1.2
1.1
—
—
—
0
0
7
12
5.99
3.04
1.1
1.1
—
—
—
0
0
92
679
1.64
3.01
3.9
3.6
27.13
147.77
e6/l
0.68
70
520
47
704
0.57
2.89
3.0
3.6
37.26
53.26
mg/l
0.67
34
474
18
80
2.37
2.69
2.1
3.4
3.98
4.32
pmol/l
0.39
12
73
35
203
1.87
2.66
7.0
8.1
—
—
—
0
0
11
36
3.17
2.61
1.1
1.3
—
—
—
0
0
6
11
5.58
2.56
1.8
1.2
—
—
—
0
0
79
580
1.58
2.55
4.9
4.5
—
—
—
0
0
96
741
1.55
2.47
4.8
4.3
91.63
108.57
e6/l
0.13
69
543
58
398
1.63
2.46
5.1
4.6
1.02
1.02
kg/l
0.04
29
281
97
754
1.54
2.40
4.0
3.9
6.53
6.25
ph
1.13
38
418
122
997
1.54
2.40
8.1
7.2
1.21
1.21
mmol/l
0.36
101
861
0
62
0.00
2.26
0.0
4.3
—
—
—
0
0
148
1652
0.64
2.14
6.6
7.5
39.78
40.41
mmol/mol
0.31
137
1535
41
267
1.67
2.11
10.5
7.3
0.76
0.75
mmol/l
0.00
34
223
11
235
0.44
1.97
1.1
1.3
—
—
—
0
0
41
273
1.63
1.94
10.5
7.2
7.42
7.41
ph
0.07
22
159
17
308
0.51
1.92
1.4
1.3
20.88
41.01
iu/ml
—
5
116
51
359
1.56
1.92
2.8
3.1
0.81
0.82
mmol/l
0.07
44
343
55
732
0.66
1.85
1.9
2.3
—
—
—
0
0
30
453
0.61
1.77
1.3
1.3
—
—
—
0
0
32
205
1.66
1.76
1.6
1.7
—
—
—
0
0
55
401
1.51
1.76
3.0
3.2
537.60
525.82
mosm/kgh2o
0.16
50
349
151
1660
0.67
1.73
4.1
5.7
1.41
1.46
mmol/l
0.70
132
1505
24
144
1.75
1.66
4.0
3.4
—
—
—
0
0
64
489
1.45
1.61
2.9
2.2
2.99
3.02
mg/l
0.02
57
427
19
107
1.85
1.61
14.2
3.8
36.93
36.91
°c
0.05
19
107
22
132
1.75
1.53
7.5
7.2
26.13
24.79
mmol/l
0.76
22
132
0
44
0.00
1.53
0.0
2.5
—
60.61
—
0
44
29
189
1.62
1.50
3.0
2.5
7.82
8.81
ug/l
0.09
21
168
25
157
1.67
1.49
3.2
3.6
83.18
87.00
ng/l
0.12
17
137
54
410
1.43
1.39
1.6
1.9
434.11
439.94
pmol/l
0.05
44
339
17
276
0.58
1.33
1.5
1.4
1.88
13.15
u/ml
—
6
103
69
837
0.74
1.25
2.3
2.9
—
—
estimate
—
0
0
143
1289
1.35
1.19
5.7
4.3
14.13
15.08
pmol/l
4.28
131
1150
0
33
0.00
1.17
0.0
2.6
—
1.18
—
0
33
0
34
0.00
1.17
0.0
2.6
—
106.06
—
0
34
0
34
0.00
1.17
0.0
2.6
—
4.03
—
0
34
0
36
0.00
1.15
0.0
2.3
—
10.47
—
0
36
9
164
0.53
1.14
1.4
1.4
—
—
—
0
0
21
136
1.61
1.14
11.0
4.0
—
—
—
0
0
154
1411
1.35
1.10
7.2
9.0
79.52
82.13
u/l
0.28
136
1334
17
260
0.62
1.06
1.4
1.3
—
—
—
0
0
156
1669
0.74
1.05
5.2
5.9
6.20
6.11
mmol/l
0.30
143
1522
148
1595
0.75
1.05
3.6
4.8
1.36
1.27
mmol/l
0.86
127
1441
159
1696
0.73
1.05
5.3
6.8
2.60
2.57
mmol/l
0.18
141
1550
5
22
2.30
1.04
1.6
1.6
159.60
399.73
mu/l
—
5
22
13
76
1.76
1.01
2.8
1.3
0.31
0.27
mg/l
—
5
28
156
1666
0.75
1.00
4.3
5.8
4.54
4.48
mmol/l
0.30
136
1525
117
1041
1.28
0.99
10.0
10.2
4.49
4.20
e9/l
0.55
100
892
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
2.7
—
5.08
—
0
31
167
1560
1.36
0.97
7.0
5.4
2.62
2.01
mu/l
0.57
148
1401
21
297
0.67
0.92
1.9
1.9
—
—
—
0
0
42
328
1.35
0.92
11.8
6.5
106.33
104.01
mmol/l
2.37
42
328
12
74
1.66
0.80
2.8
3.1
1.01
2.92
ratio
—
5
39
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
2.7
—
—
—
0
0
12
184
0.63
0.78
3.7
4.8
—
0.14
—
0
49
0
28
0.00
0.76
0.0
3.8
—
—
—
0
0
5
24
2.11
0.75
1.4
1.7
9.52
10.65
%
—
5
24
14
92
1.56
0.74
2.4
2.5
—
—
—
0
0
6
110
0.53
0.74
1.2
1.3
—
—
—
0
0
6
110
0.53
0.74
1.2
1.4
—
—
—
0
0
12
177
0.66
0.67
3.3
4.3
—
0.43
—
0
54
46
382
1.26
0.66
4.4
4.0
72.12
207.52
ng/l
1.11
41
327
11
164
0.65
0.64
1.5
1.5
—
—
—
0
0
5
29
1.74
0.64
1.6
1.4
—
—
—
0
0
5
29
1.74
0.64
1.6
1.4
—
—
—
0
0
5
29
1.74
0.64
1.6
1.4
—
—
—
0
0
5
29
1.74
0.64
1.6
1.4
—
—
—
0
0
70
793
0.82
0.63
5.4
5.9
2.30
2.73
ug/l
0.28
63
697
12
174
0.67
0.62
1.4
2.2
—
0.00
estimate
—
0
39
0
20
0.00
0.60
0.0
1.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
13
184
0.69
0.60
1.4
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
193.31
—
0
7
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
0.97
—
0
22
64
558
1.21
0.59
5.3
4.2
0.00
0.01
estimate
0.50
12
201
0
23
0.00
0.58
0.0
1.7
—
—
—
0
0
14
98
1.46
0.58
1.1
1.3
—
37.56
—
0
8
30
240
1.29
0.58
2.7
3.4
7.38
7.39
ph
0.52
18
145
8
54
1.50
0.58
1.1
1.1
—
—
—
0
0
174
1669
1.26
0.56
22.7
18.6
33.40
25.95
mg/l
1.66
142
1408
44
516
0.81
0.56
2.5
3.2
346.94
367.46
umol/l
0.58
31
437
19
248
0.74
0.55
1.2
1.3
—
—
—
0
0
20
155
1.32
0.49
2.3
2.3
—
—
—
0
0
32
381
0.81
0.47
3.0
5.7
—
—
—
0
0
5
83
0.59
0.46
5.2
1.9
—
—
—
0
0
102
944
1.16
0.46
6.0
6.2
1.68
1.93
e9/l
1.14
88
825
15
195
0.75
0.44
1.7
3.1
64.18
69.12
e9/l
—
9
140
17
132
1.31
0.42
3.4
2.3
0.58
0.65
%
0.46
17
132
0
15
0.00
0.41
0.0
1.4
—
55682.80
—
0
10
0
15
0.00
0.41
0.0
1.4
—
0.75
—
0
6
0
16
0.00
0.41
0.0
1.4
—
1.51
—
0
16
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
100
930
1.14
0.41
6.0
6.1
0.59
0.60
e9/l
0.11
84
782
103
960
1.14
0.41
7.5
6.2
0.19
0.19
e9/l
0.08
89
824
0
17
0.00
0.41
0.0
1.4
—
33.66
—
0
12
0
17
0.00
0.41
0.0
1.1
—
40126.00
—
0
10
8
60
1.35
0.41
13.1
11.5
—
—
—
0
0
5
34
1.48
0.40
1.2
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
0.95
—
0
18
0
18
0.00
0.40
0.0
3.8
—
—
—
0
0
102
951
1.14
0.40
4.7
4.3
0.00
0.00
estimate
-0.00
13
222
104
971
1.14
0.40
4.6
4.4
0.00
0.02
estimate
0.50
12
207
5
35
1.44
0.39
1.2
1.1
—
—
—
0
0
120
1132
1.14
0.39
7.8
5.1
7.19
6.85
mmol/l
0.85
110
1085
17
134
1.29
0.38
3.4
2.3
1.26
1.11
%
0.53
17
134
23
190
1.24
0.36
1.0
1.4
—
—
—
0
0
100
936
1.13
0.36
6.0
6.1
0.04
0.04
e9/l
0.12
86
787
102
960
1.12
0.33
4.7
4.3
0.00
7.22
estimate
0.50
13
225
68
627
1.13
0.31
5.6
5.7
—
—
—
0
0
12
152
0.78
0.30
1.3
1.6
—
—
—
0
0
8
107
0.74
0.30
2.5
3.0
—
—
—
0
0
7
56
1.26
0.29
1.4
1.5
—
11.34
—
0
5
22
186
1.20
0.29
2.4
2.8
65.53
66.53
g/l
0.24
15
170
89
839
1.11
0.27
9.6
13.3
0.00
0.00
e9/l
0.10
72
680
79
742
1.10
0.25
3.2
3.0
107.26
148.95
ug/l
1.66
70
687
20
233
0.84
0.25
1.4
1.4
—
—
—
0
0
30
337
0.87
0.24
1.8
1.4
2.07
2.46
g/l
0.67
16
195
13
157
0.82
0.23
6.0
4.0
—
—
—
0
0
173
1764
0.89
0.22
13.1
13.7
23.94
25.27
u/l
0.62
163
1708
110
1056
1.09
0.21
4.7
7.2
10.31
12.05
umol/l
1.49
101
1001
5
42
1.20
0.21
4.8
3.2
0.56
1.01
nmol/l
—
5
37
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
178.72
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
86.10
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
94.83
—
0
12
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
56
599
0.91
0.20
2.8
2.7
44.78
71.93
u/l
1.87
49
552
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
4.6
—
21.85
—
0
6
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
10
81
1.25
0.19
1.2
1.3
—
—
—
0
0
179
1760
1.12
0.19
30.6
22.7
139.85
139.66
mmol/l
0.38
173
1732
179
1760
1.12
0.19
29.6
23.0
3.96
4.01
mmol/l
1.59
173
1730
7
62
1.13
0.17
1.3
1.2
—
—
—
0
0
10
116
0.86
0.12
1.2
1.2
—
—
—
0
0
83
857
0.95
0.11
5.9
6.2
0.71
0.65
%
0.49
77
799
58
602
0.95
0.09
2.3
2.6
—
—
—
0
0
70
721
0.96
0.08
5.1
4.3
0.00
0.03
estimate
0.78
12
190
7
66
1.06
0.08
1.0
1.1
—
—
—
0
0
84
859
0.96
0.07
5.9
6.3
8.88
9.03
%
0.21
76
806
85
869
0.96
0.07
5.9
6.3
25.08
26.16
%
0.39
80
819
172
1704
1.05
0.07
17.4
16.3
—
—
—
0
0
8
91
0.87
0.07
1.3
1.3
—
—
—
0
0
179
1775
1.06
0.07
29.9
25.5
76.39
83.42
umol/l
3.22
173
1761
36
346
1.05
0.06
1.7
2.4
2.20
2.26
g/l
0.25
27
321
14
151
0.92
0.05
3.4
2.8
131.64
127.97
g/l
0.32
14
145
81
795
1.03
0.05
4.2
4.4
26.78
42.75
ng/l
1.65
65
645
84
855
0.97
0.05
5.8
6.2
2.85
2.82
%
0.05
77
799
38
368
1.04
0.04
1.8
2.5
11.80
13.22
umol/l
0.67
32
341
47
481
0.97
0.03
2.6
3.5
—
0.13
—
0
15
11
102
1.08
0.03
1.4
2.1
1.76
1.57
g/l
0.22
11
95
44
432
1.02
0.01
1.8
1.7
1.30
1.60
mg/l
0.37
33
353
178
1787
0.97
0.01
35.0
28.2
243.69
240.38
e9/l
0.27
173
1749
178
1787
0.97
0.01
35.0
28.1
4.35
4.45
e12/l
1.79
173
1740
178
1787
0.97
0.01
35.1
28.2
6.97
6.81
e9/l
0.42
173
1739
46
467
0.98
0.01
3.0
3.3
1.04
0.84
ug/l
0.26
40
317
100
993
1.01
0.01
14.4
15.3
1.32
1.31
inr
0.12
91
829
15
151
0.99
0.00
1.6
3.1
152.13
240.61
ng/l
0.72
15
136
37
367
1.01
0.00
1.4
1.2
0.59
1.31
u/ml
—
7
96
0
8
0.00
0.00
0.0
1.4
—
78.63
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
3717.80
—
0
5
0
6
0.00
-0.00
0.0
4.7
—
45.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
7.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
14.76
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
6.76
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
0.00
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
41.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
2.2
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: FTD – Frontotemporal dementia

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).