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Intracranial and intraspinal abscess and granuloma

EFO MESH Endpoint Browser PheWeb

G6_CNSABSC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

480

4. Check minimum number of events

None

480

5. Include endpoints

None

480

6. Filter based on genotype QC (FinnGen only)

433

Control definitions (FinnGen only)

Control exclude
G6_NEUINFL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3266 1188 2050
Only index persons 2599 978 1621
Unadjusted period prevalence (%)
Whole population 0.05 0.03 0.06
Only index persons 0.05 0.04 0.06
Median age at first event (years)
Whole population 56.24 57.43 55.51
Only index persons 55.94 56.94 55.33

-FinnGen-

Key figures

All Female Male
Number of individuals 433 181 252
Unadjusted period prevalence (%) 0.09 0.06 0.12
Median age at first event (years) 61.01 59.15 62.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
444
Matched controls
4440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
241.4
209
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
43.4
193.7
121
38
G06.0
ICD-10 Finland
Intracranial abscess and granuloma
+∞
184.6
164
*
M46.4
ICD-10 Finland
Discitis, unspecified
61.3
96.0
54
10
J04AB02
ATC
rifampicin; systemic
41.5
94.4
58
16
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.4
84.5
107
132
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
19.7
70.8
57
33
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
12.2
70.5
76
74
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
22.7
62.7
47
23
G06.2
ICD-10 Finland
Extradural and subdural abscess, unspecified
+∞
61.9
58
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
60.8
176
495
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.9
60.3
137
312
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
98.9
55.4
60
7
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.7
53.5
175
536
ZXD05
NOMESCO Finland
Urgent procedure
4.3
51.1
228
875
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.1
50.4
53
49
N03AX14
ATC
levetiracetam; systemic
12.1
49.5
52
48
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.9
46.5
98
205
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.7
43.8
50
52
AA1AD
NOMESCO Finland
CT of head and brain
3.9
43.6
224
925
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
14.0
43.1
41
32
J01FF01
ATC
clindamycin; systemic
3.8
42.4
207
823
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.3
41.6
140
428
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
5.6
38.4
82
172
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
54.1
37.4
44
9
AAM00
NOMESCO Finland
Puncture and evacuation of intracerebral abscess
+∞
37.0
35
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
10.4
35.6
41
43
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
11.8
34.2
36
33
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.2
32.7
61
112
ZXD35
NOMESCO Finland
Usual procedure
8.0
31.1
44
60
JN4BD
NOMESCO Finland
Extensive body CT
4.0
28.8
95
280
A41.9
ICD-10 Finland
Sepsis, unspecified
6.7
28.6
48
79
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
28.5
173
752
R50.9
ICD-10 Finland
Fever, unspecified
3.5
27.3
117
411
N02AA05
ATC
oxycodone; systemic
3.2
25.9
141
571
JN4AD
NOMESCO Finland
Body CT examination
3.6
25.9
101
333
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.7
25.9
43
70
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
8.8
25.6
33
40
WX882
NOMESCO Finland
High dependency care
8.5
25.5
34
43
N03AX16
ATC
[U] pregabalin
3.0
24.8
150
643
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
24.1
282
1698
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
24.0
153
674
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
8.7
23.8
31
38
J01CF05
ATC
flucloxacillin; systemic
4.2
23.4
69
186
AAM30
NOMESCO Finland
Evacuation of epidural or subdural empyema
126.6
22.8
24
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.3
21.7
38
65
SPAT1255
SPAT
Intravenous administration of medicine
4.5
21.3
56
138
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.5
20.7
42
83
AAM10
NOMESCO Finland
Excision of intracerebral abscess
+∞
19.9
19
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
19.7
203
1115
B18.2
ICD-10 Finland
Chronic viral hepatitis C
15.6
19.7
32
22
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
19.6
96
360
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.4
19.4
79
265
R4110
NOMESCO Finland
Physiotherapy
2.6
19.4
169
858
TKC20
NOMESCO Finland
Catheterisation of bladder
3.9
19.4
62
177
WX872
NOMESCO Finland
Intensive care
4.4
19.1
51
127
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.9
18.9
61
175
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
104.5
18.7
20
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.3
18.5
32
54
R4120
NOMESCO Finland
Occupational therapy
4.0
18.4
56
154
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
14.5
18.0
30
22
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
7.7
17.6
25
34
N02AX02
ATC
tramadol; systemic, rectal
2.4
17.5
237
1449
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
25.3
17.5
24
10
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
17.1
74
257
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
26.8
17.1
23
9
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
17.0
120
545
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.6
16.8
42
99
WX892
NOMESCO Finland
Monitored bed care
3.6
16.8
60
184
J01MA12
ATC
levofloxacin; systemic
2.6
16.8
120
548
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
16.8
16
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.1
16.7
49
131
L28
ICPC
Limited function/disability (L)
2.6
16.6
116
523
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
16.6
82
308
A41.8
ICD-10 Finland
Other specified sepsis
6.6
16.5
27
43
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
16.2
16.4
26
17
ZXC95
NOMESCO Finland
Use of surgical navigator
17.6
16.3
25
15
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.5
16.0
32
62
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
15.9
91
370
Z3226
NOMESCO Finland
Physiotherapist
2.6
15.7
111
502
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.8
15.7
37
83
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
15.7
15
*
A46
ICD-10 Finland
Erysipelas
2.7
15.5
102
445
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.9
15.4
86
344
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
15.4
122
583
P19
ICPC
Drug abuse
29.8
15.3
20
7
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
14.7
14
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
14.7
75
286
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
14.4
211
1303
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
14.1
67
245
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
55.2
13.9
16
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.7
13.8
33
75
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
13.6
13
*
A40.8
ICD-10 Finland
Other streptococcal sepsis
12.0
13.5
24
21
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
13.4
85
362
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
13.4
55
184
Z3231
NOMESCO Finland
Registered nurse
2.2
13.3
150
828
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
13.1
72
285
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
13.1
337
2554
Z2446
NOMESCO Finland
Social worker
3.4
13.1
50
160
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
13.1
50
160
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.8
13.0
70
274
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.7
12.8
30
67
N18
ICPC
Paralysis/weakness
6.4
12.6
21
34
AAK00
NOMESCO Finland
Cranioplasty
+∞
12.6
12
*
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.4
12.5
32
77
XA800
NOMESCO Finland
Neuropsychological investigation
4.3
12.3
33
82
B01AB05
ATC
enoxaparin; parenteral
2.1
12.3
166
979
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.4
12.2
31
74
WX402
NOMESCO Finland
General anaesthesia
2.3
12.2
117
602
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
12.0
42
127
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
11.8
146
830
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
17.0
11.8
18
11
C03CA01
ATC
furosemide; systemic
2.1
11.6
161
954
ZXE00
NOMESCO Finland
One hour or less
2.0
11.5
184
1148
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
11.5
11
*
32200
ICD-8 Finland
Intracranial and intraspinal abscess, Intracerebralis
+∞
11.5
11
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
11.4
68
280
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.8
11.3
26
57
A28
ICPC
Limited function/disability NOS
2.3
11.3
102
510
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.7
11.2
37
107
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.7
11.2
37
107
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
13.2
11.2
19
15
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.5
11.1
40
123
S97
ICPC
Chronic ulcer skin
3.1
11.1
49
171
W19
ICD-10 Finland
Unspecified fall
2.8
11.1
61
241
Z72.2
ICD-10 Finland
Drug use
44.5
11.0
13
*
N03AF02
ATC
oxcarbazepine; oral
4.5
10.9
27
63
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.0
10.9
20
19
M54.5
ICD-10 Finland
Low back pain
2.0
10.8
174
1082
A06AD11
ATC
lactulose; oral
2.4
10.8
85
400
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
10.7
79
360
ZXA00
NOMESCO Finland
Right side
2.1
10.7
138
792
WX002
NOMESCO Finland
Sedation and analgesia
2.2
10.7
104
535
Z2221
NOMESCO Finland
Medical doctor
2.1
10.5
138
798
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
112.6
10.5
11
*
3240A
ICD-9 Finland
Intracranial and intraspinal abscess, Intracranial abscess
+∞
10.5
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
10.4
104
540
N03AX18
ATC
lacosamide; systemic
16.5
10.4
16
10
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
10.4
35
103
M48.0
ICD-10 Finland
Spinal stenosis
2.5
10.3
73
327
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
8.8
10.2
21
25
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.6
10.1
24
54
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.8
10.1
32
90
N02BF02
ATC
pregabalin; oral
3.1
10.1
45
158
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
41.1
10.0
12
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.4
9.9
36
111
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
17.2
9.9
15
9
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
56.3
9.7
11
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
9.6
64
278
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
9.6
49
186
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.5
190
1258
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
9.5
47
175
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
4.1
9.5
26
66
SPAT1254
SPAT
Administration of medicine
2.3
9.4
76
360
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
9.4
43
153
WX750
NOMESCO Finland
Hyperbaric oxygen therapy
+∞
9.4
9
*
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
22.3
9.4
13
6
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.7
9.4
30
85
WX730
NOMESCO Finland
Conventional respirator
9.8
9.3
18
19
N03AX12
ATC
[U] gabapentin; oral
2.2
9.3
89
453
J01XX08
ATC
linezolid; systemic
14.1
9.2
15
11
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
9.2
174
1129
A10AB05
ATC
insulin aspart; parenteral
2.7
9.2
52
208
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.9
9.1
20
42
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.8
9.1
28
77
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
9.1
48
185
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.0
9.1
26
68
N05BA01
ATC
diazepam; systemic, rectal
2.3
9.1
74
352
A02BC02
ATC
pantoprazole; systemic
1.9
9.1
317
2495
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
9.0
142
867
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
9.0
177
1162
L70
ICPC
Infection of musculoskeletal system
19.1
9.0
13
7
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
24.6
8.9
12
5
ZX120
NOMESCO Finland
Intravenous
2.6
8.9
55
230
N06AX21
ATC
duloxetine; oral
2.4
8.8
67
309
R5110, ,
SPAT
2.7
8.8
51
207
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
8.6
49
197
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
8.6
36
122
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
28.1
8.5
11
*
J01DB01
ATC
cefalexin; oral
2.2
8.5
370
3101
Z71.8
ICD-10 Finland
Other specified counselling
1.9
8.5
160
1033
EBA10
NOMESCO Finland
Operative extraction of tooth
2.4
8.4
63
288
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
8.4
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
8.2
151
965
R4190
NOMESCO Finland
Nutritional therapy
3.8
8.1
25
69
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
34.0
8.1
10
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
8.1
66
314
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
22.5
8.0
11
5
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
22.5
8.0
11
5
WX704
NOMESCO Finland
Intubation
2.7
8.0
44
173
S76
ICPC
Skin infection other
3.0
8.0
36
127
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
8.0
52
223
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
7.9
85
452
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.3
7.8
30
96
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
45.8
7.7
9
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
45.8
7.7
9
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.9
7.7
23
62
J01MA14
ATC
moxifloxacin; systemic
2.4
7.7
53
233
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
7.6
40
154
N03AE01
ATC
clonazepam; systemic
3.0
7.6
34
120
QDB10, ,
SPAT
4.0
7.5
21
54
N28
ICPC
Limited function/disability (N)
7.9
7.4
16
21
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.9
7.4
22
59
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
7.4
79
418
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
7.4
44
181
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.4
7.3
18
29
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
7.3
7
*
G992, G061,
ICD-10 Finland
+∞
7.3
7
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
7.3
36
134
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
16.1
7.3
11
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
7.2
126
788
N29
ICPC
Neurological sympt/complt other
6.8
7.2
17
26
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.2
7.1
19
47
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.1
7.1
30
102
K08.3
ICD-10 Finland
Retained dental root
2.5
7.1
46
197
J01CF02
ATC
cloxacillin; systemic
4.3
7.1
18
43
H02AB07
ATC
prednisone; oral
2.2
7.1
67
338
N05AH04
ATC
quetiapine; oral
2.0
7.0
91
517
R33
ICD-10 Finland
Retention of urine
2.4
6.9
49
219
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
8.5
6.9
14
17
RS221, ,
NOMESCO Finland
6.9
6.9
16
24
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.8
150
1001
K90
ICPC
Stroke/cerebrovascular accident
3.8
6.8
21
58
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.8
6.8
18
32
F10.24
ICD-10 Finland
Alcohol depence active use
5.8
6.8
18
32
N03AG01
ATC
valproic acid; systemic, rectal
2.8
6.8
35
133
P15
ICPC
Chronic alcohol abuse
3.5
6.8
23
68
G40.10
ICD-10 Finland
Simple partial seizures
17.0
6.8
10
6
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.8
131
843
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
7.4
6.8
15
21
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
6.7
75
402
S01.0
ICD-10 Finland
Open wound of scalp
2.4
6.7
47
208
ABC63
NOMESCO Finland
Decompression of thoracic spinal cord
22.9
6.7
9
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
22.9
6.7
9
*
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
8.0
6.7
14
18
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
12.5
6.6
11
9
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
12.5
6.6
11
9
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
12.5
6.6
11
9
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
6.6
29
101
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
6.5
45
198
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
6.5
24
75
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.4
6.5
23
70
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
6.5
27
91
N02BF01
ATC
gabapentin; oral
2.2
6.4
54
259
IFC01, ,
SPAT
70.8
6.4
7
*
NK3AT
NOMESCO Finland
Muscle puncture with ultrasound guidance
70.8
6.4
7
*
S18
ICPC
Laceration/cut
1.7
6.4
217
1623
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
6.4
21
61
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.9
6.3
18
47
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
18.3
6.3
9
5
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
18.3
6.3
9
5
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
7.2
6.3
14
20
N71
ICPC
Meningitis/encephalitis
+∞
6.3
6
*
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
+∞
6.3
6
*
G83.4
ICD-10 Finland
Cauda equina syndrome
27.1
6.2
8
*
J01DA01
ATC
[U] cefalexin
1.7
6.2
267
2112
ZXA05
NOMESCO Finland
Left side
1.8
6.1
114
722
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
12.8
6.1
10
8
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
6.8
6.1
14
21
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.3
6.1
17
33
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.1
52
252
N06AX11
ATC
mirtazapine; oral
1.7
6.1
152
1047
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.7
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
211
604
5.75
73.36
3.8
2.1
—
—
—
0
0
289
1147
5.35
66.00
11.8
4.5
—
—
—
0
0
40
36
12.11
38.52
3.2
1.1
—
—
—
0
0
146
552
3.45
30.73
7.8
6.0
1.06
1.03
mmol/l
0.49
135
516
253
1326
3.11
30.36
14.5
6.5
—
—
—
0
0
49
78
6.94
30.17
1.7
1.1
3.76
3.90
mmol/l
0.21
44
73
153
617
3.26
28.73
2.1
1.9
—
—
—
0
0
166
710
3.14
28.09
5.3
3.4
0.79
0.82
mmol/l
2.48
160
672
71
175
4.64
27.20
3.0
1.9
9.30
2.86
ug/l
0.55
66
156
110
373
3.59
27.11
10.4
7.2
9.91
10.17
mmol/l
0.13
104
353
44
70
6.87
27.05
3.0
1.3
—
—
—
0
0
46
79
6.38
26.27
2.7
1.2
569.60
13.05
e6/l
1.26
35
59
125
473
3.29
25.76
2.8
1.7
—
—
—
0
0
46
81
6.22
25.62
2.8
1.3
449.47
1468.03
e6/l
0.34
36
65
129
509
3.16
24.66
13.5
9.0
4.97
5.14
kpa
1.19
124
489
129
509
3.16
24.66
13.5
9.0
13.19
12.14
kpa
1.45
124
491
299
1856
2.87
24.08
17.0
6.8
2.81
2.89
%
0.26
291
1745
127
504
3.13
23.97
13.4
9.1
0.75
0.88
mmol/l
0.12
103
430
298
1850
2.86
23.93
17.1
6.9
0.64
0.68
%
0.67
290
1730
302
1893
2.86
23.71
16.7
6.9
24.58
27.18
%
4.09
292
1801
288
1762
2.81
23.70
10.0
5.3
32.14
35.63
g/l
13.17
275
1655
298
1859
2.83
23.54
17.0
7.0
9.37
9.01
%
0.97
290
1750
127
509
3.09
23.51
14.3
9.1
7.41
7.42
ph
0.20
71
294
297
1861
2.80
23.06
16.6
6.8
60.01
57.46
%
3.30
289
1776
230
1274
2.67
22.83
4.6
2.4
—
—
—
0
0
69
191
4.09
22.58
1.8
1.9
1.94
1.47
g/l
2.80
62
172
311
2015
2.81
22.25
15.9
6.7
0.65
0.59
e9/l
2.99
278
1743
311
2021
2.80
22.02
16.1
6.7
0.04
0.04
e9/l
0.10
277
1751
320
2111
2.85
21.97
12.9
7.3
10.86
11.92
umol/l
0.94
312
2022
313
2051
2.78
21.61
16.0
6.9
1.74
1.88
e9/l
1.39
285
1824
94
330
3.34
21.58
3.8
2.4
11.25
11.05
g/l
0.12
89
303
229
1304
2.56
20.93
4.8
3.3
44.88
87.64
e6/l
0.40
188
1018
104
396
3.12
20.81
3.0
2.6
0.18
0.21
g/l
2.09
97
369
206
1123
2.56
20.56
5.4
3.2
—
—
—
0
0
328
2249
2.75
19.83
20.4
10.6
4.48
4.12
e9/l
1.76
292
1978
311
2081
2.65
19.71
16.8
7.0
0.19
0.20
e9/l
0.03
281
1835
118
506
2.81
18.89
1.9
1.4
—
—
—
0
0
292
1919
2.52
18.84
17.1
13.9
1.23
1.26
inr
0.51
246
1591
181
965
2.48
18.50
4.5
2.4
—
—
—
0
0
299
1998
2.52
18.42
14.8
7.7
1.20
1.21
mmol/l
1.46
272
1730
184
1006
2.42
17.61
3.3
2.1
3.17
3.03
mg/l
0.27
165
869
275
1801
2.38
17.24
13.4
6.9
1.19
1.21
mmol/l
2.54
262
1670
237
1457
2.34
17.20
5.6
4.0
109.65
96.79
e6/l
0.13
189
1063
150
770
2.43
16.29
3.8
3.0
490.97
547.10
mosm/kgh2o
2.73
136
683
195
1124
2.31
16.21
4.9
3.2
0.59
0.52
e6/l
0.12
156
842
167
916
2.32
15.45
3.6
2.7
8.06
5.51
e6/l
0.72
154
842
91
381
2.75
14.97
2.8
2.9
61.96
70.77
e9/l
1.42
65
285
33
70
5.01
14.96
1.8
1.5
—
—
—
0
0
324
2353
2.39
14.96
11.9
5.5
6.79
6.74
mmol/l
0.17
313
2246
99
438
2.62
14.57
8.0
3.6
7.37
7.38
ph
0.61
54
265
90
380
2.72
14.53
17.1
8.7
—
—
—
0
0
123
606
2.42
14.39
3.3
2.4
19.09
23.54
%
2.43
118
572
36
85
4.52
14.36
8.0
2.2
—
—
—
0
0
95
416
2.63
14.25
8.2
3.6
0.91
1.98
mmol/l
1.81
86
361
23
36
6.68
14.23
1.5
1.3
—
—
—
0
0
106
496
2.49
13.82
3.0
2.8
1.63
1.83
%
1.62
99
444
264
1796
2.16
13.81
4.8
2.8
—
—
estimate
—
0
0
128
653
2.35
13.77
3.4
2.3
2.20
2.29
g/l
0.81
122
608
43
121
3.83
13.61
10.7
1.7
—
—
—
0
0
133
695
2.30
13.50
3.5
2.4
10.45
13.17
umol/l
3.52
128
654
28
57
5.18
13.28
13.9
2.0
—
—
—
0
0
43
124
3.73
13.14
10.5
1.7
—
—
—
0
0
43
124
3.73
13.14
10.9
1.7
—
—
—
0
0
41
118
3.73
12.56
11.0
1.7
—
—
—
0
0
37
99
3.99
12.55
11.1
1.7
—
—
—
0
0
251
1714
2.07
12.52
23.5
11.9
0.00
0.00
e9/l
0.58
207
1421
21
36
6.07
11.90
3.4
1.4
—
—
—
0
0
21
36
6.07
11.90
1.3
1.5
1994.60
2159.58
e6/l
0.08
15
24
82
364
2.54
11.83
4.4
2.6
198.46
32.26
u/l
0.50
70
307
109
552
2.29
11.73
1.9
1.6
—
—
—
0
0
121
647
2.20
11.37
4.2
3.1
2.02
2.18
e6/l
0.10
70
333
369
2973
2.43
11.37
22.0
8.9
92.30
78.90
u/l
5.62
361
2823
199
1289
1.99
11.09
4.8
2.7
59.38
64.18
u/l
0.35
189
1202
40
124
3.45
10.96
11.0
1.7
—
—
—
0
0
93
461
2.29
10.43
1.8
1.7
—
—
—
0
0
27
66
4.29
10.30
2.1
1.4
—
—
—
0
0
63
271
2.54
9.63
2.8
3.0
—
—
—
0
0
133
780
2.01
9.58
4.3
4.1
457.86
357.86
ng/l
0.16
107
634
93
479
2.19
9.44
5.2
3.1
10.71
9.04
umol/l
0.22
78
428
202
1372
1.87
9.31
6.1
3.7
36.85
34.69
u/l
0.30
193
1300
41
143
3.06
9.29
3.7
4.9
55.14
92.19
mg/l
0.41
36
125
41
143
3.06
9.29
3.7
4.9
34.33
43.48
mg/l
0.30
36
126
65
289
2.46
9.26
3.8
3.3
7.42
7.42
ph
0.14
59
239
39
133
3.12
9.18
3.7
4.5
3.67
2.70
ratio
0.20
24
80
182
1200
1.88
9.17
7.0
4.2
7.40
7.40
ph
0.04
137
873
120
692
2.01
8.99
1.8
1.7
1086.30
1180.75
nmol/l
0.51
94
530
26
69
3.94
8.91
1.7
1.4
68.00
59.85
mmol/l
0.37
20
62
40
143
2.98
8.68
1.4
1.3
—
—
—
0
0
242
1767
1.81
8.58
2.5
2.1
97.29
96.15
pmol/l
0.13
145
945
29
86
3.54
8.50
3.2
2.8
—
—
—
0
0
72
348
2.28
8.48
5.8
4.9
1.00
0.45
%
1.48
45
120
65
301
2.36
8.45
1.9
1.6
—
—
—
0
0
33
107
3.25
8.43
2.1
1.4
15824.95
14739.44
e6/l
0.06
21
82
22
55
4.16
8.16
1.6
3.0
—
—
—
0
0
177
1191
1.81
8.12
15.1
6.7
—
—
—
0
0
29
89
3.42
8.08
1.2
1.8
—
—
—
0
0
61
281
2.36
8.01
5.5
4.0
98.91
85.29
ng/l
0.39
52
252
16
20
8.25
7.66
1.3
1.2
630.50
171.98
iu/ml
0.98
16
20
15
17
9.09
7.60
4.8
1.8
—
—
—
0
0
27
84
3.36
7.37
1.4
1.2
—
—
—
0
0
230
1703
1.73
7.35
2.9
2.5
74.06
76.75
nmol/l
0.74
205
1534
18
42
4.42
7.28
1.2
1.3
—
—
—
0
0
34
124
2.89
7.14
1.6
2.4
13.92
12.37
mg/l
0.44
29
118
18
32
5.82
6.83
1.4
1.5
20376.83
34886.88
e6/l
0.37
12
16
31
111
2.93
6.73
1.3
1.3
—
—
—
0
0
60
302
2.14
6.36
2.6
3.1
247.01
230.40
ng/l
0.11
53
270
31
118
2.75
6.03
15.7
10.7
1.64
1.31
mmol/l
0.94
25
103
315
2615
1.70
6.00
8.0
4.7
—
2.79
—
0
7
19
54
3.63
5.94
1.4
1.3
8.45
5.17
u/ml
0.30
11
23
216
1635
1.63
5.90
5.2
3.5
6.22
6.21
ph
0.07
112
948
30
114
2.75
5.86
5.2
3.2
7.26
2.20
index
0.85
19
69
13
19
7.01
5.77
1.7
2.9
1128.00
975.79
u/ml
0.11
13
19
16
31
5.31
5.75
1.6
1.5
—
—
—
0
0
17
37
4.74
5.54
1.1
3.3
—
—
—
0
0
66
363
1.96
5.50
5.9
5.1
0.90
0.85
%
0.10
40
130
24
84
2.96
5.44
1.4
1.2
223.19
286.60
u/ml
0.47
16
40
173
1260
1.61
5.41
3.5
3.4
2279.94
1268.49
ng/l
0.60
156
1079
64
352
1.96
5.33
2.7
2.4
7.47
7.74
ug/l
0.04
59
313
118
784
1.69
5.28
2.0
1.4
2.92
2.60
g/l
0.71
88
492
62
341
1.95
5.16
6.2
5.2
0.08
0.17
%
0.69
36
107
16
36
4.57
5.10
1.4
1.6
—
—
—
0
0
16
45
3.65
5.09
5.9
3.4
—
—
—
0
0
103
1498
0.59
5.08
3.3
3.3
—
—
—
0
0
10
12
8.49
5.08
1.2
1.5
—
—
—
0
0
42
201
2.20
5.05
2.5
2.2
0.00
4.11
estimate
0.50
12
61
162
1177
1.59
5.04
2.2
1.7
18.28
20.25
nmol/l
1.04
148
994
224
1756
1.56
4.99
4.3
2.9
176.55
139.31
ug/l
0.94
209
1636
128
881
1.64
4.96
2.1
1.7
2.00
1.41
mg/l
0.88
111
692
21
73
2.97
4.83
4.2
2.9
2.20
2.25
mmol/l
0.04
16
46
187
1417
1.55
4.79
6.1
3.4
6.59
8.00
mmol/l
3.62
157
1194
33
146
2.36
4.76
3.6
3.8
202.00
201.17
mg/l
0.01
20
60
40
193
2.18
4.72
1.9
1.5
0.32
0.37
mg/l
0.21
22
87
15
35
4.40
4.67
2.0
3.4
811.27
1171.17
mg
0.44
15
35
22
82
2.77
4.48
1.5
1.4
—
—
—
0
0
14
32
4.48
4.47
1.8
1.8
11.47
10.78
%
0.23
14
32
41
205
2.10
4.44
4.0
3.5
—
—
—
0
0
61
351
1.86
4.44
6.3
5.4
2.41
0.12
%
0.47
34
99
193
1492
1.52
4.42
2.6
2.1
—
—
—
0
0
14
33
4.35
4.36
1.0
1.2
—
—
—
0
0
7
6
11.82
4.29
1.3
1.0
—
—
—
0
0
175
1334
1.51
4.23
4.7
3.5
2.34
2.35
mmol/l
0.63
158
1204
81
522
1.67
3.99
1.3
1.2
—
—
—
0
0
15
48
3.20
3.96
1.1
1.2
—
—
—
0
0
249
2058
1.48
3.96
6.0
3.9
24.69
3.87
estimate
0.39
55
420
110
775
1.56
3.76
4.0
2.9
2.45
2.45
mmol/l
0.12
91
693
13
354
0.35
3.75
1.4
1.4
—
—
—
0
0
12
29
4.22
3.73
5.6
2.6
0.58
0.83
index
0.73
12
29
15
50
3.07
3.72
1.1
1.1
—
—
u/ml
—
0
0
36
184
2.04
3.70
2.8
2.4
—
—
—
0
0
68
429
1.69
3.62
2.9
4.7
4.74
32.67
ug/l
0.89
57
361
32
158
2.10
3.60
4.0
3.9
25.18
25.06
mmol/l
0.09
32
147
6
6
10.11
3.50
2.0
1.5
—
—
—
0
0
244
2043
1.43
3.41
5.9
3.8
0.00
0.00
estimate
-0.00
50
414
58
358
1.71
3.35
7.1
4.5
7.38
7.35
ph
1.30
51
258
10
23
4.42
3.33
1.3
2.3
113.00
71.92
umol/l
—
5
13
247
2082
1.42
3.28
5.9
3.9
0.04
0.78
estimate
0.47
54
386
299
2610
1.45
3.26
7.4
3.5
77.90
52.94
u/l
2.35
284
2454
57
354
1.70
3.22
2.8
2.5
1.03
0.45
e6/l
0.35
57
339
18
74
2.49
3.08
1.2
1.1
—
—
—
0
0
8
16
5.07
3.06
1.1
1.1
—
—
—
0
0
59
376
1.66
3.03
2.8
2.1
0.00
0.04
estimate
0.49
14
75
19
82
2.38
2.95
1.3
1.1
—
—
—
0
0
78
537
1.55
2.92
1.4
1.3
440.00
469.62
titre
0.05
22
131
22
103
2.20
2.85
1.3
1.5
143.80
236.33
miu/ml
—
5
47
13
47
2.82
2.84
1.6
2.7
0.59
1.40
g/24h
—
8
32
194
1598
1.38
2.80
5.0
3.9
33.55
60.22
ng/l
0.65
155
1175
23
111
2.13
2.78
1.7
1.4
200.43
282.30
ug/g
1.32
18
64
29
153
1.96
2.77
1.6
2.1
6.10
5.64
iu/ml
—
6
43
13
48
2.76
2.74
1.0
1.1
—
—
—
0
0
12
40
3.05
2.71
2.3
2.4
—
—
—
0
0
10
29
3.50
2.70
1.0
1.1
105.80
97.93
pmol/l
—
10
29
7
15
4.72
2.60
1.0
2.4
—
—
—
0
0
6
11
5.51
2.55
1.7
2.6
—
—
—
0
0
44
273
1.68
2.52
1.7
1.8
—
—
—
0
0
138
1092
1.38
2.49
1.5
1.4
—
—
—
0
0
8
21
3.86
2.47
1.0
1.1
—
—
—
0
0
6
12
5.05
2.41
2.3
1.3
—
—
—
0
0
9
27
3.38
2.40
1.1
1.8
—
—
—
0
0
164
1345
1.35
2.34
4.3
3.6
83.03
53.79
mg/l
0.53
119
905
10
34
2.98
2.29
1.5
1.4
—
—
—
0
0
52
348
1.56
2.22
1.9
1.4
—
—
—
0
0
394
3716
1.54
2.17
51.4
16.7
33.28
23.99
mg/l
7.44
374
3075
24
408
0.56
2.02
1.2
1.6
—
—
—
0
0
113
894
1.35
2.00
7.7
5.5
—
—
—
0
0
131
1061
1.33
1.99
4.2
2.9
342.28
352.68
umol/l
0.54
116
927
5
11
4.58
1.94
5.8
1.8
—
—
—
0
0
6
16
3.79
1.94
4.3
2.9
0.64
0.58
mmol/l
—
6
16
164
1383
1.29
1.84
5.0
4.2
23.17
9.38
mg/mmol
0.83
118
897
7
23
3.08
1.80
1.7
4.5
15.17
16.45
%
—
7
23
20
109
1.87
1.80
1.6
1.3
6.12
8.74
u/l
0.82
15
89
13
60
2.20
1.79
1.5
1.6
—
—
—
0
0
13
60
2.20
1.79
1.5
1.6
—
—
—
0
0
13
60
2.20
1.79
1.5
1.6
—
—
—
0
0
13
60
2.20
1.79
1.5
1.6
—
—
—
0
0
10
41
2.47
1.65
1.4
1.2
—
—
—
0
0
5
14
3.60
1.62
1.2
2.1
0.60
2.43
%
—
5
14
5
14
3.60
1.62
1.2
1.6
—
—
—
0
0
64
480
1.39
1.58
3.4
2.6
269.12
123.22
ug/g
0.74
57
387
67
516
1.35
1.42
4.5
3.3
5.78
4.88
e9/l
0.45
56
450
10
46
2.20
1.41
1.9
1.6
82.09
89.98
%
—
10
46
9
40
2.28
1.41
1.7
1.3
16.37
34.84
ng/l
—
9
40
7
29
2.44
1.39
1.0
1.1
—
—
—
0
0
5
120
0.41
1.39
16.6
12.5
—
—
—
0
0
398
3823
1.40
1.34
54.0
20.2
3.99
3.99
mmol/l
0.03
393
3743
5
18
2.80
1.29
10.4
1.4
2.16
1.91
umol/l
—
5
12
5
118
0.42
1.26
1.0
1.1
1.46
1.51
g/l
—
5
118
5
19
2.65
1.22
1.0
1.1
119.00
145.81
nmol/l
—
5
19
5
19
2.65
1.22
1.2
1.0
2000.40
1369.63
miu/ml
—
5
19
5
19
2.65
1.22
1.0
1.8
1.26
1.07
nmol/l
—
5
12
8
38
2.13
1.19
1.3
2.0
—
—
—
0
0
62
486
1.32
1.18
1.4
1.3
—
—
—
0
0
23
338
0.66
1.12
1.0
1.4
—
—
—
0
0
107
906
1.24
1.11
6.0
4.0
1.02
1.02
kg/l
0.12
79
599
8
41
1.97
1.09
1.4
1.2
—
—
—
0
0
38
280
1.39
1.08
1.2
1.2
—
—
—
0
0
59
466
1.31
1.08
1.6
1.3
—
—
—
0
0
6
123
0.48
1.06
1.2
1.2
0.75
0.91
g/l
—
6
123
26
179
1.48
1.05
3.3
1.9
—
—
—
0
0
359
3430
1.24
1.03
5.5
5.1
1.82
1.96
mu/l
1.32
327
3149
97
820
1.23
1.03
2.0
1.8
519.15
25327945.45
pmol/l
0.74
86
687
12
201
0.59
1.03
1.1
1.1
—
—
—
0
0
5
107
0.46
1.02
1.0
1.6
—
—
—
0
0
12
68
1.79
1.01
3.1
3.3
0.77
0.93
nmol/l
—
7
56
5
110
0.45
1.01
1.0
1.1
—
0.70
—
0
20
56
444
1.30
1.00
2.5
2.5
13.49
13.72
nmol/l
0.06
51
403
9
49
1.85
0.99
1.4
1.2
—
—
—
0
0
9
50
1.82
0.97
2.4
1.6
—
—
—
0
0
359
3723
0.81
0.92
5.0
5.4
4.31
4.57
mmol/l
5.10
330
3465
6
28
2.16
0.92
1.8
3.9
9.93
8.34
mmol/l
—
6
28
6
28
2.16
0.92
1.2
1.2
3.70
0.42
u/ml
—
6
15
11
63
1.76
0.91
1.3
1.1
1.41
1.48
g/l
0.27
11
58
8
46
1.75
0.83
1.1
1.1
—
—
—
0
0
358
3704
0.83
0.82
4.9
5.3
1.36
1.42
mmol/l
1.91
322
3425
73
619
1.21
0.77
1.2
1.3
9.15
11.30
u/ml
0.13
26
241
0
28
0.00
0.76
0.0
1.0
—
323.28
—
0
18
9
53
1.71
0.76
1.1
1.2
—
—
—
0
0
11
67
1.66
0.75
4.8
3.1
5.03
4.49
e9/l
0.33
11
67
16
108
1.50
0.74
1.3
1.3
2.90
2.80
u/ml
—
5
15
23
168
1.39
0.73
2.4
2.9
—
—
—
0
0
5
25
2.01
0.73
1.2
1.2
12.20
29.41
%
—
5
17
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
128
1149
1.16
0.71
6.9
3.9
0.00
0.01
estimate
0.78
48
379
37
293
1.29
0.70
8.1
3.7
—
—
—
0
0
298
2841
1.15
0.68
4.4
4.1
15.04
14.82
pmol/l
0.79
275
2582
367
3774
0.84
0.67
5.8
6.1
2.45
2.68
mmol/l
5.54
336
3500
286
2723
1.14
0.66
5.1
4.3
—
0.17
—
0
6
10
62
1.63
0.65
2.1
2.5
—
—
—
0
0
7
44
1.60
0.65
1.7
1.2
—
—
—
0
0
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
152
1649
0.88
0.61
2.0
2.0
1.44
1.40
mmol/l
0.22
130
1379
15
105
1.44
0.61
1.3
1.2
—
—
—
0
0
8
54
1.49
0.57
2.0
2.2
32.63
32.94
pg
—
8
54
76
670
1.16
0.54
1.4
1.3
37.19
33.83
iu/ml
0.06
19
213
11
74
1.50
0.54
4.8
2.7
8.35
8.32
pmol/l
0.00
11
74
7
106
0.65
0.49
1.1
1.1
—
—
—
0
0
11
76
1.46
0.48
1.9
1.9
—
—
—
0
0
7
47
1.50
0.47
1.6
1.3
—
—
nmol/l
—
0
0
16
121
1.33
0.45
2.5
2.4
53.53
88.93
ug/min
0.56
11
69
13
95
1.38
0.44
4.9
2.9
67.00
58.41
%
1.40
13
95
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
5
34
1.48
0.40
1.0
1.4
—
—
—
0
0
5
36
1.39
0.38
2.2
1.8
—
—
—
0
0
24
198
1.22
0.37
1.3
1.2
—
—
—
0
0
349
3563
0.90
0.35
4.3
4.5
1.40
1.32
mmol/l
1.04
318
3280
172
1634
1.09
0.35
5.4
5.4
1.74
2.31
ug/l
1.43
149
1478
28
239
1.18
0.32
1.2
1.2
—
—
—
0
0
120
1131
1.08
0.29
5.5
3.3
0.00
0.08
estimate
0.55
37
320
7
57
1.23
0.29
1.9
1.2
—
—
—
0
0
13
103
1.27
0.28
1.3
1.2
—
—
—
0
0
14
113
1.25
0.27
1.5
1.2
—
—
—
0
0
15
180
0.83
0.24
1.3
1.2
—
—
—
0
0
358
3633
0.92
0.24
5.5
5.3
6.15
6.03
mmol/l
0.60
328
3339
388
3834
1.10
0.23
33.0
14.9
—
—
—
0
0
19
221
0.85
0.23
1.1
1.2
63.80
140.74
u/ml
—
5
82
0
10
0.00
0.21
0.0
6.2
—
9.30
—
0
10
0
10
0.00
0.21
0.0
3.1
—
40.40
—
0
10
0
12
0.00
0.21
0.0
1.1
—
47.56
—
0
12
6
48
1.25
0.20
1.7
1.2
—
—
—
0
0
90
853
1.07
0.20
1.4
1.3
1.17
1.41
u/ml
0.18
18
256
103
982
1.06
0.19
3.1
3.1
0.66
0.74
ug/l
0.51
67
614
14
118
1.19
0.19
1.0
1.1
—
—
—
0
0
396
3934
1.06
0.11
28.7
12.8
29.50
27.43
u/l
0.95
390
3830
43
407
1.06
0.11
1.8
1.5
—
—
—
0
0
10
110
0.91
0.05
9.7
4.7
—
—
—
0
0
156
1568
0.99
0.01
6.6
3.8
0.00
0.01
estimate
0.69
38
339
358
3573
1.01
0.01
8.0
6.7
40.16
39.75
mmol/mol
0.30
334
3358
31
315
0.98
0.00
3.4
2.2
5.83
6.02
ph
0.70
23
214
403
4028
1.01
0.00
64.6
25.7
262.52
244.54
e9/l
4.76
397
3957
403
4030
1.00
-0.00
64.4
25.6
4.24
4.53
e12/l
18.02
396
3948
0
5
0.00
-0.00
0.0
6.0
—
6.62
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
39.14
—
0
7
403
4030
1.00
-0.00
66.0
26.1
37.98
40.77
%
18.08
398
3983
0
7
0.00
-0.00
0.0
1.1
—
2.12
—
0
7
403
4030
1.00
-0.00
64.4
25.7
7.46
6.74
e9/l
5.67
396
3947
5
50
1.00
-0.00
2.0
3.3
86.20
32.78
u/ml
—
5
50

Mortality – FinRegistry

↥

Association

Association between endpoint G6_CNSABSC and mortality.

Females

Parameter HR [95% CI] p-value
G6_CNSABSC 2.858 [2.2, 3.71] < 0.001
Birth year 0.996 [0.99, 1.0] 0.345

During the follow-up period (1.1.1998 — 31.12.2019), 249 out of 827 females with G6_CNSABSC died.

Males

Parameter HR [95% CI] p-value
G6_CNSABSC 3.057 [2.48, 3.77] < 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 1360 males with G6_CNSABSC died.

Mortality risk

Mortality risk for people of age

years, who have G6_CNSABSC.

N-year risk Females Males
1 0.342% 0.607%
5 2.032% 3.043%
10 4.479% 7.957%
15 7.857% 15.197%
20 13.336% 24.356%

Relationships between endpoints

↥

Index endpoint: G6_CNSABSC – Intracranial and intraspinal abscess and granuloma

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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