No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
818 |
4. Check minimum number of eventsNone |
818 |
5. Include endpointsNone |
818 |
6. Filter based on genotype QC (FinnGen only) |
695 |
Control definitions (FinnGen only)
- Control exclude
- G6_HYDROCEPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified hydrocephalus
based on the number of shared cases.
Similar with more cases:
- Hydrocephalus
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6159 | 3013 | 3080 |
| Only index persons | 4640 | 2370 | 2270 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.09 | 0.09 |
| Only index persons | 0.09 | 0.09 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 56.12 | 58.51 | 53.59 |
| Only index persons | 54.55 | 57.40 | 51.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 695 | 385 | 310 |
| Unadjusted period prevalence (%) | 0.14 | 0.14 | 0.14 |
| Median age at first event (years) | 60.92 | 59.32 | 62.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 718
- Matched controls
- 7180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
307.7
288
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
307.7
574
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
6268.7
307.7
354
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
2765.6
207.7
191
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
200.7
183
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
200.7
183
*
AA1AA
NOMESCO Finland
Head X-ray examination
64.8
197.7
110
20
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
18.4
193.3
168
117
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
181.1
166
*
AA1AD
NOMESCO Finland
CT of head and brain
7.1
149.2
475
1546
AAF00
NOMESCO Finland
Ventriculostomy
538.3
138.2
133
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
133.6
124
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.3
109.4
191
338
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
104.8
98
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
100.4
94
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
30.5
95.8
64
23
N03AX14
ATC
levetiracetam; systemic
13.2
87.4
87
74
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.4
75.1
177
408
AAF15
NOMESCO Finland
Ventriculoatrial shunt
+∞
74.3
70
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
16.6
70.8
61
40
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
7.5
69.5
108
165
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
735.6
69.2
67
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.4
67.2
78
83
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
11.5
63.9
69
66
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.3
62.2
145
328
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.0
61.4
80
99
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
11.2
55.1
60
58
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
53.8
51
*
R51.80
ICD-10 Finland
Headache
3.8
52.7
206
686
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
10.5
45.9
52
53
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
7.0
45.6
73
114
N03AG01
ATC
valproic acid; systemic, rectal
5.2
45.1
102
222
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
43.8
238
962
N29
ICPC
Neurological sympt/complt other
10.4
41.4
47
48
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
13.7
41.1
39
30
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
408.8
39.5
39
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
13.3
39.5
38
30
ZXD05
NOMESCO Finland
Urgent procedure
2.8
39.1
299
1445
XA800
NOMESCO Finland
Neuropsychological investigation
5.6
36.6
74
145
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
10.5
35.7
40
40
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
13.9
34.1
32
24
34793
ICD-8 Finland
Other disease of brain, Hydrocephalus acquisitus NUD
+∞
33.6
32
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
33.5
105
294
N03AF02
ATC
oxcarbazepine; oral
6.5
33.2
56
92
TAB00
NOMESCO Finland
Lumbar puncture
5.0
32.0
73
159
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
31.9
192
805
N18
ICPC
Paralysis/weakness
8.3
31.8
43
55
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.3
31.8
43
55
N28
ICPC
Limited function/disability (N)
8.8
31.1
40
48
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
326.4
31.1
31
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
29.1
172
710
N99
ICPC
Neurological disease other
10.8
29.1
32
31
L28
ICPC
Limited function/disability (L)
2.7
28.7
209
961
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
27.3
26
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
25.0
27.3
38
16
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.4
27.1
36
45
G04BD07
ATC
tolterodine; oral
4.2
26.4
74
190
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
25.2
69
174
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
24.3
318
1874
2132
FHL
Ventricular operators sunt
+∞
24.1
23
*
F03
ICD-10 Finland
Unspecified dementia
4.1
23.9
69
181
A28
ICPC
Limited function/disability NOS
2.4
23.1
202
999
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
+∞
23.0
22
*
R42
ICD-10 Finland
Dizziness and giddiness
2.3
23.0
225
1169
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
22.9
77
225
SPAT1229
SPAT
Assessment of need for aid
3.3
22.3
91
301
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
22.3
22.3
32
15
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
7.3
22.2
33
47
K90
ICPC
Stroke/cerebrovascular accident
5.1
22.1
48
100
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
22.0
21
*
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
+∞
20.9
20
*
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
+∞
20.9
20
*
SPAT1216
SPAT
Assessment of functional ability
2.5
20.9
161
748
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.7
20.6
33
51
N03AB02
ATC
phenytoin; systemic
7.7
20.5
29
39
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
20.3
113
446
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
20.2
224
1217
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.0
20.1
31
46
G93.0
ICD-10 Finland
Cerebral cysts
36.9
19.9
25
7
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
15.9
19.9
32
21
2133
FHL
Suntin revisio
+∞
19.9
19
*
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.4
19.8
40
78
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
19.8
87
301
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
6.1
19.3
34
58
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
194.9
18.6
19
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.9
18.2
33
58
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
15.1
17.7
29
20
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
17.7
152
737
G93.2
ICD-10 Finland
Benign intracranial hypertension
97.5
17.6
19
*
H47.2
ICD-10 Finland
Optic atrophy
32.4
17.1
22
7
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
17.1
280
1741
R53
ICD-10 Finland
Malaise and fatigue
2.1
16.9
225
1298
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
64.9
16.8
19
*
G91
ICD-10 Finland
Hydrocephalus
+∞
16.7
16
*
PA2AD
NOMESCO Finland
CT angiography of brain
16.8
16.7
26
16
G04BD08
ATC
solifenacin; oral
3.0
16.6
78
280
H53.4
ICD-10 Finland
Visual field defects
5.2
15.9
33
66
R41.0
ICD-10 Finland
Disorientation, unspecified
4.1
15.6
44
113
N05BA09
ATC
clobazam; oral
15.2
15.4
25
17
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
15.2
15.4
25
17
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
15.3
87
346
U04
ICPC
Incontinence urine
3.0
15.3
71
253
P20
ICPC
Memory disturbance
2.2
15.0
144
727
WX730
NOMESCO Finland
Conventional respirator
6.7
15.0
24
37
N03AX18
ATC
lacosamide; systemic
15.5
15.0
24
16
N05CD08
ATC
midazolam; nasal, systemic
4.6
14.9
36
82
N05AH03
ATC
olanzapine; systemic
3.1
14.9
66
229
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
57.9
14.8
17
*
N06AB04
ATC
citalopram; systemic
2.1
14.8
174
951
Q03.0
ICD-10 Finland
Malformations of aqueduct of Sylvius
+∞
14.6
14
*
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
27.8
14.3
19
7
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
14.3
108
492
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
14.3
128
628
R32
ICD-10 Finland
Unspecified urinary incontinence
4.4
14.2
36
85
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
14.2
26
46
M03BX01
ATC
baclofen; systemic
5.1
14.2
30
61
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.7
14.1
46
131
N30.0
ICD-10 Finland
Acute cystitis
2.1
14.1
149
781
N05AH04
ATC
quetiapine; oral
2.1
14.0
150
791
N05BA01
ATC
diazepam; systemic, rectal
2.3
13.9
119
573
N03AX09
ATC
lamotrigine; oral
3.5
13.8
48
143
A06AD11
ATC
lactulose; oral
2.1
13.7
143
746
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
13.6
80
323
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
13.6
13
*
S06.0
ICD-10 Finland
Concussion
2.4
13.5
107
497
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
142.6
13.5
14
*
SPAT1301
SPAT
No procedures
1.9
13.2
252
1617
N05AX08
ATC
risperidone; systemic
2.4
13.2
95
423
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
13.2
100
456
183
Kela drug reimbursment
Lamotrigin and topiramate
11.2
13.1
24
22
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
13.1
108
511
R11
ICD-10 Finland
Nausea and vomiting
2.5
13.0
90
393
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
13.0
42
119
ZXC86
NOMESCO Finland
Use of endoscopic device
23.0
12.9
18
8
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
12.9
137
717
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.4
12.9
92
408
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
10.8
12.8
24
23
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
12.8
145
778
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.3
12.8
105
495
WX882
NOMESCO Finland
High dependency care
3.9
12.7
38
102
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
15.8
12.7
20
13
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
12.5
12
*
2130
FHL
Ventricular atrial shunt
+∞
12.5
12
*
H47.1
ICD-10 Finland
Papilloedema, unspecified
13.5
12.5
21
16
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
12.5
163
921
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.4
12.4
45
138
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
16.2
12.2
19
12
SPAT1254
SPAT
Administration of medicine
2.1
12.1
131
690
XCK00
NOMESCO Finland
Perimetry
2.9
12.0
60
222
R50.9
ICD-10 Finland
Fever, unspecified
2.1
12.0
132
700
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.5
12.0
41
121
N03AF01
ATC
carbamazepine; oral, rectal
3.0
11.9
55
195
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
6.0
11.9
21
36
WX402
NOMESCO Finland
General anaesthesia
1.9
11.8
169
984
SPAT1262
SPAT
Handing over of treatment supplies
2.0
11.7
139
758
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
23.3
11.6
16
7
N05AB03
ATC
perphenazine; systemic, rectal
3.7
11.6
37
104
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
11.5
82
363
G81.1
ICD-10 Finland
Spastic hemiplegia
121.9
11.5
12
*
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
121.9
11.5
12
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.2
11.4
30
73
H53.2
ICD-10 Finland
Diplopia
3.6
11.4
38
110
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.7
11.3
62
241
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.3
11.3
44
141
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.5
11.3
73
309
XKC03
NOMESCO Finland
Water cystometry
3.7
11.2
35
97
SPAT1167
SPAT
Insertion of urinary catheter
3.7
11.2
35
97
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.8
11.1
20
35
N06DA02
ATC
donepezil; oral
2.5
11.0
72
306
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.6
10.9
63
252
T90.5
ICD-10 Finland
Sequelae of intracranial injury
8.2
10.7
23
29
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
60.9
10.6
12
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
10.6
67
1407
SPAT1053
SPAT
Memory test
2.0
10.5
126
687
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
10.4
10
*
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
10.4
10
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.7
10.3
24
53
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.2
220
1445
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
4.3
10.2
26
62
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
10.1
151
888
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
3.0
9.9
45
158
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.8
9.9
52
198
G04BD12
ATC
mirabegron; oral
2.0
9.8
109
577
GBB00
NOMESCO Finland
Tracheostomy
8.0
9.7
21
27
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
55.8
9.7
11
*
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
4.7
9.6
22
48
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
15.3
9.5
15
10
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
101.3
9.4
10
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
101.3
9.4
10
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
101.3
9.4
10
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
30.5
9.4
12
*
K91
ICPC
Cerebrovascular disease
5.2
9.4
19
37
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.2
9.4
19
37
AAK80
NOMESCO Finland
Partial excision of skull cap
+∞
9.4
9
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
12.6
9.4
16
13
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.0
9.4
26
66
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
22.0
9.4
13
6
N02AA05
ATC
oxycodone; systemic
1.8
9.2
154
935
WX704
NOMESCO Finland
Intubation
2.4
9.2
65
287
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.1
9.1
19
38
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
8.5
9.1
19
23
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
7.2
9.1
21
30
G40.10
ICD-10 Finland
Simple partial seizures
10.2
9.1
17
17
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.6
9.0
20
27
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
4.8
8.9
20
43
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
10.9
8.8
16
15
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
9.6
8.8
17
18
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.3
8.7
22
52
ZXD00
NOMESCO Finland
Emergency procedure
3.7
8.6
27
75
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
8.6
53
219
R60.0
ICD-10 Finland
Localized oedema
2.0
8.6
106
583
Z2445
NOMESCO Finland
Psychologist
2.9
8.5
39
138
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
27.9
8.5
11
*
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.4
8.4
21
49
AAF45
NOMESCO Finland
Fenestration of intracranial cyst
+∞
8.3
8
*
J01EA01
ATC
trimethoprim; systemic
1.7
8.3
194
1291
WYA20
NOMESCO Finland
Home visit
3.8
8.2
25
68
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.6
8.2
27
78
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
10.2
8.1
15
15
N06AX11
ATC
mirtazapine; oral
1.6
8.0
246
1754
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
7.4
8.0
18
25
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
7.1
7.8
18
26
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
7.1
7.8
18
26
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.7
7.8
24
66
N06AB10
ATC
escitalopram; oral
1.8
7.8
138
850
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.6
7.8
25
71
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
45.5
7.7
9
*
ABE50
NOMESCO Finland
Occipitocervical decompression
45.5
7.7
9
*
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
45.5
7.7
9
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
7.7
104
588
G04BD04
ATC
oxybutynin; oral, transdermal
2.3
7.7
57
257
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
7.6
207
1428
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
18.6
7.6
11
6
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
7.6
103
583
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
25.3
7.6
10
*
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
25.3
7.6
10
*
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
25.3
7.6
10
*
R5110, ,
SPAT
2.1
7.6
76
387
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
10.2
7.6
14
14
L29
ICPC
Musculoskeletal sympt/complt other
2.1
7.5
74
375
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.0
7.5
21
54
S01EC01
ATC
acetazolamide; systemic
3.4
7.4
26
78
G20
ICD-10 Finland
Parkinson disease
3.1
7.4
31
104
D33.30
ICD-10 Finland
Acoustic neuroma
13.5
7.4
12
9
R33
ICD-10 Finland
Retention of urine
2.1
7.4
71
356
N06AX16
ATC
venlafaxine; oral
1.9
7.4
101
574
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
9.5
7.3
14
15
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
7.3
105
606
G94.1
ICD-10 Finland
Hydrocephalus in neoplastic disease
+∞
7.3
7
*
AAW99
NOMESCO Finland
Other intracranial operation
+∞
7.3
7
*
2139
FHL
Other measure in this category
+∞
7.3
7
*
XKD00
NOMESCO Finland
Uroflowmetry
1.8
7.3
109
637
G03.9
ICD-10 Finland
Meningitis, unspecified
15.9
7.2
11
7
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.5
7.2
24
70
G04BD09
ATC
trospium; oral
3.3
7.2
26
80
N03AE01
ATC
clonazepam; systemic
2.5
7.2
45
188
R26.0
ICD-10 Finland
Ataxic gait
20.3
7.1
10
5
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
6.7
7.1
17
26
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
7.1
61
292
R27.0
ICD-10 Finland
Ataxia, unspecified
12.2
7.1
12
10
F06.7
ICD-10 Finland
Mild cognitive disorder
2.9
7.1
33
118
N04AA02
ATC
biperiden; systemic
3.9
7.0
20
52
N80
ICPC
Head injury other
3.3
6.9
25
77
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.5
6.9
41
167
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.9
119
727
SPAT1234
SPAT
Support of social functional capacity
2.4
6.8
47
205
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
9.4
6.8
13
14
F22.0
ICD-10 Finland
Delusional disorder
5.7
6.8
18
32
R55
ICD-10 Finland
Syncope and collapse
1.9
6.6
93
532
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
12.4
6.6
11
9
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.8
6.5
32
118
N30.9
ICD-10 Finland
Cystitis, unspecified
2.2
6.5
56
269
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.0
6.5
18
46
Q04.6
ICD-10 Finland
Congenital cerebral cysts
70.5
6.4
7
*
SPAT1240
SPAT
Therapeutic discussion
2.0
6.4
67
347
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.7
6.4
34
131
ZXA00
NOMESCO Finland
Right side
1.6
6.3
192
1352
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.7
6.3
33
126
SPAT1260
SPAT
Consultation of another employee
1.7
6.3
123
776
ZXD35
NOMESCO Finland
Usual procedure
2.9
6.3
28
98
AAK85
NOMESCO Finland
Replantation of previously excised part of skull cap
+∞
6.3
6
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
6.3
6
*
74209
ICD-8 Finland
Congenital hydrocephalus, Unspecified
+∞
6.3
6
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
6.3
6
*
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
+∞
6.3
6
*
G41.2
ICD-10 Finland
Complex partial status epilepticus
26.9
6.2
8
*
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
3.0
6.2
27
93
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
6.2
114
707
S72.0
ICD-10 Finland
Fracture of neck of femur
2.4
6.2
40
170
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
7.8
6.1
13
17
OAB43, ,
SPAT
0.5
6.1
58
1073
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
6.1
28
100
G40.89
ICD-10 Finland
Other epilepsy
10.1
6.0
11
11
JDB10
NOMESCO Finland
Percutaneous gastrostomy
5.3
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
184
50
49.14
306.20
3.1
1.1
—
—
—
0
0
227
129
25.27
292.96
3.0
1.3
24.03
12.98
e6/l
0.59
183
86
227
131
24.88
290.86
3.0
1.3
1188.05
1086.19
e6/l
0.04
192
91
230
147
22.55
280.60
2.5
1.3
494.50
515.75
mg/l
0.16
225
140
76
22
38.52
121.85
2.7
1.2
—
—
—
0
0
56
42
14.38
60.25
1.1
1.0
231.42
320.50
ng/l
1.29
24
30
56
42
14.38
60.25
1.1
1.0
553.00
600.60
ng/l
0.20
28
30
56
42
14.38
60.25
1.1
1.0
36.31
42.84
ng/l
0.24
23
28
59
94
6.75
36.02
5.4
5.5
11.18
11.70
mg/l
0.31
54
87
31
26
12.42
30.93
1.6
1.1
—
—
—
0
0
67
179
4.03
22.58
3.0
1.5
—
—
—
0
0
323
1987
2.14
21.44
3.0
2.2
157.33
287.52
u/l
1.76
308
1885
162
759
2.46
20.61
10.5
8.3
1.70
1.08
mmol/l
1.66
137
628
494
3708
2.06
17.66
9.3
5.4
6.63
6.65
mmol/l
0.12
486
3530
418
3016
1.92
16.04
13.4
15.8
1.17
1.28
inr
5.47
379
2529
410
2971
1.89
15.19
10.3
6.9
1.20
1.21
mmol/l
3.48
387
2741
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
23
36
6.57
14.17
1.2
1.2
—
—
—
0
0
350
2457
1.83
13.91
4.5
4.0
63.41
76.31
ng/l
0.13
276
1815
46
133
3.63
13.82
1.7
1.5
—
—
—
0
0
196
1145
1.98
13.77
2.3
2.0
—
—
—
0
0
432
3285
1.79
12.67
10.2
7.3
1.21
1.21
mmol/l
0.50
368
2841
182
1064
1.95
12.63
3.7
3.5
0.83
0.81
mmol/l
1.77
169
999
277
1852
1.81
12.60
6.8
4.1
0.00
0.00
estimate
0.74
100
644
150
826
2.03
12.31
2.4
1.9
—
—
—
0
0
26
53
5.05
12.24
1.1
1.1
—
—
—
0
0
32
79
4.19
11.96
2.0
1.4
289.59
275.02
mosm/kgh2o
2.65
27
58
154
876
1.96
11.46
2.3
1.9
—
—
—
0
0
154
900
1.91
10.50
8.7
6.8
105.42
104.27
mmol/l
2.35
154
900
127
701
1.99
10.23
8.3
7.3
—
—
—
0
0
87
422
2.21
9.84
10.7
9.6
95.22
93.93
%
1.80
87
417
20
40
5.11
9.61
1.7
1.9
—
—
—
0
0
114
622
1.99
9.45
5.0
3.6
—
—
—
0
0
14
8
17.82
9.43
1.6
1.0
—
—
—
0
0
220
1479
1.70
9.24
3.9
2.8
6.65
5.66
e6/l
0.50
210
1354
494
4084
1.67
9.06
8.0
5.0
4602.08
2046.50
e6/l
0.49
12
76
230
1574
1.68
8.99
4.9
4.1
90.50
88.58
%
0.60
223
1543
54
223
2.54
8.77
9.6
3.9
1.46
1.36
mmol/l
0.20
54
217
328
2478
1.60
8.50
6.8
4.1
0.02
0.03
estimate
0.12
81
571
146
901
1.78
8.20
5.8
5.7
1.00
1.07
mmol/l
2.53
136
830
73
359
2.15
7.97
2.1
1.5
—
—
—
0
0
287
2126
1.58
7.93
4.6
3.6
66.12
88.43
e6/l
0.24
245
1642
123
731
1.82
7.81
4.9
4.3
5.93
5.76
kpa
0.77
118
709
216
1503
1.63
7.71
6.6
4.3
1.02
1.02
kg/l
0.13
162
1020
173
1141
1.68
7.61
1.9
1.8
1348.91
1175.66
nmol/l
2.03
144
851
117
703
1.79
7.14
5.1
4.4
1.71
1.71
mmol/l
0.00
105
589
91
508
1.91
7.01
6.4
4.0
1.22
1.22
mmol/l
0.49
82
438
19
35
5.55
6.95
1.2
1.0
1.69
1.10
u/l
—
10
20
402
3294
1.50
6.56
6.5
4.2
11.54
4.94
estimate
0.23
116
709
18
35
5.25
6.35
1.1
1.1
—
—
—
0
0
58
287
2.11
6.25
3.0
1.8
0.82
2.17
ug/l
0.73
50
254
351
2818
1.48
6.20
3.6
2.8
—
—
estimate
—
0
0
189
1335
1.56
6.14
1.8
1.8
478.70
10598265.57
pmol/l
0.50
157
1104
16
30
5.43
5.87
3.2
2.4
64.50
44.25
umol/l
1.59
16
25
261
1995
1.48
5.80
2.8
2.6
52.14
62.31
u/l
1.92
242
1855
394
3266
1.46
5.74
6.5
4.1
0.00
0.00
estimate
-0.00
110
686
522
5765
0.65
5.72
5.4
5.9
2.65
2.65
mmol/l
0.00
484
5321
349
2830
1.45
5.69
6.3
5.0
34.56
35.56
g/l
2.71
319
2642
18
52
3.52
5.48
1.4
1.4
0.64
0.98
promille
0.49
12
41
397
3322
1.44
5.33
6.6
4.2
0.00
0.46
estimate
0.51
106
663
300
2386
1.44
5.31
5.5
4.3
129.99
130.19
e6/l
0.00
244
1709
39
177
2.27
5.22
1.8
1.6
—
—
—
0
0
510
5634
0.67
5.22
4.7
5.1
1.39
1.47
mmol/l
3.76
469
5191
21
540
0.37
5.16
1.8
2.0
3.66
3.46
ratio
0.25
16
429
40
185
2.23
5.13
1.8
1.7
—
—
—
0
0
395
3333
1.41
4.88
6.4
6.5
10.04
12.12
umol/l
2.85
375
3173
515
5661
0.68
4.88
4.8
5.2
4.51
4.58
mmol/l
0.77
473
5251
201
1507
1.46
4.77
3.0
2.5
—
—
—
0
0
7
5
14.12
4.58
1.7
1.0
—
—
—
0
0
12
24
5.07
4.33
1.1
1.0
—
—
—
0
0
277
2236
1.39
4.27
3.6
3.3
2.35
2.36
mmol/l
0.17
252
2022
233
1832
1.40
4.18
4.5
3.5
0.52
0.43
e6/l
0.22
196
1360
195
2475
0.71
4.03
1.9
2.0
1.68
1.34
mmol/l
1.01
160
2062
22
87
2.58
4.00
2.0
1.5
—
—
—
0
0
12
28
4.34
3.83
1.1
1.0
1667.33
1396.18
miu/ml
0.30
12
28
76
483
1.64
3.78
2.8
2.7
59.32
64.27
ml/min/173m2
0.54
31
211
492
5386
0.73
3.76
4.1
4.3
1.38
1.27
mmol/l
1.82
448
4922
95
640
1.56
3.72
2.6
2.1
373.84
389.10
nmol/l
0.30
87
600
13
34
3.87
3.70
10.7
12.9
648.77
839.00
nmol/l
0.79
13
34
76
491
1.61
3.55
2.3
1.6
—
—
—
0
0
17
402
0.41
3.49
1.6
1.8
3.31
3.45
mmol/l
0.18
11
290
9
19
4.78
3.24
1.1
1.2
—
—
—
0
0
31
157
2.02
3.24
1.4
1.5
—
—
—
0
0
521
5612
0.74
3.15
5.0
5.3
5.96
5.96
mmol/l
0.02
474
5119
6
8
7.55
3.06
1.2
1.5
—
—
—
0
0
508
5483
0.75
3.02
6.5
6.6
39.39
39.44
mmol/mol
0.04
474
5107
47
753
0.60
2.97
4.3
4.9
29.69
32.19
%
1.13
36
483
39
223
1.79
2.88
1.4
1.3
—
—
—
0
0
6
9
6.71
2.87
1.0
1.3
—
—
—
0
0
6
10
6.04
2.70
1.3
2.1
19.02
14.69
umol/l
—
6
10
8
19
4.25
2.68
1.0
1.1
—
—
—
0
0
8
19
4.25
2.68
1.0
1.2
—
—
—
0
0
78
543
1.49
2.66
2.2
2.5
5.83
7.12
ug/l
0.17
64
480
19
86
2.24
2.66
2.1
1.5
—
—
—
0
0
42
254
1.69
2.58
10.8
4.3
8.72
8.46
kpa
0.48
42
247
5
7
7.18
2.55
1.2
1.4
—
—
—
0
0
9
26
3.49
2.49
1.1
1.3
—
—
—
0
0
17
76
2.27
2.45
1.3
1.4
—
—
—
0
0
5
8
6.28
2.37
1.6
1.9
—
—
—
0
0
13
52
2.53
2.37
1.8
2.3
1.88
2.50
u/field
—
8
26
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
17
4.15
2.36
2.1
2.9
97.71
132.65
%
—
7
17
7
17
4.15
2.36
1.0
1.2
—
—
—
0
0
213
1777
1.28
2.36
6.6
3.6
0.01
0.06
estimate
0.44
87
544
228
1921
1.27
2.33
1.9
1.7
19.65
20.55
nmol/l
0.32
204
1604
22
114
1.96
2.22
7.1
2.7
9.00
8.32
pmol/l
0.15
22
114
37
226
1.67
2.22
1.6
1.5
31.02
25.33
iu/l
0.39
31
186
79
1067
0.71
2.22
2.5
3.1
0.78
0.80
ug/l
0.05
55
698
11
41
2.71
2.21
1.1
1.0
—
—
—
0
0
164
1333
1.30
2.21
3.1
2.9
2.47
2.46
mmol/l
0.67
150
1191
11
42
2.64
2.15
1.0
1.2
—
—
—
0
0
63
443
1.46
2.08
8.4
4.7
2.19
1.88
mmol/l
0.32
49
333
5
11
4.57
1.94
2.0
3.5
101.20
169.36
%
—
5
11
59
416
1.46
1.93
1.8
1.7
—
—
—
0
0
15
71
2.14
1.93
1.7
1.5
0.28
0.37
nmol/l
—
10
53
158
1303
1.27
1.89
4.2
4.3
331.98
406.71
ng/l
0.15
120
1050
25
144
1.76
1.87
1.4
1.4
—
—
—
0
0
7
165
0.42
1.81
1.3
1.1
1.54
1.54
g/l
—
7
165
23
132
1.77
1.75
1.6
1.5
—
—
—
0
0
7
164
0.42
1.68
1.4
1.5
1333.84
941.69
mu/l
—
7
138
495
4644
1.21
1.60
8.5
8.2
83.41
81.10
u/l
0.40
473
4385
10
43
2.34
1.59
3.1
2.6
—
—
—
0
0
13
64
2.05
1.55
2.8
2.9
12.13
12.12
index
—
8
43
8
33
2.44
1.54
2.1
1.5
—
—
—
0
0
81
1028
0.76
1.53
1.3
1.3
7.17
11.42
u/ml
0.56
39
366
5
15
3.35
1.52
1.2
1.3
—
—
—
0
0
34
226
1.53
1.52
1.8
2.1
200.82
508.99
ug/l
0.89
28
211
34
495
0.67
1.48
1.3
1.5
—
—
—
0
0
8
170
0.46
1.48
1.4
1.1
0.85
0.90
g/l
—
8
170
14
73
1.94
1.44
1.3
1.8
—
—
—
0
0
14
73
1.94
1.44
1.1
1.2
—
—
—
0
0
21
126
1.69
1.41
1.4
1.4
—
—
—
0
0
17
287
0.58
1.41
2.4
2.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
184
1.54
1.33
3.0
3.0
0.42
0.39
iu/ml
0.16
14
98
34
482
0.69
1.31
2.3
2.5
13.99
13.27
nmol/l
0.21
28
436
593
6129
0.81
1.27
13.1
12.3
27.72
25.56
u/l
0.95
574
5959
8
36
2.24
1.24
2.1
1.5
—
—
—
0
0
19
116
1.66
1.22
2.4
1.7
—
—
—
0
0
5
19
2.64
1.22
1.0
1.1
—
—
—
0
0
5
19
2.64
1.22
1.0
1.1
—
—
—
0
0
22
140
1.59
1.21
1.5
1.3
—
—
—
0
0
22
140
1.59
1.21
1.5
1.3
—
—
—
0
0
608
5874
1.23
1.20
28.6
16.8
25.09
24.78
mg/l
0.09
548
4851
194
1711
1.18
1.20
2.7
2.3
3.43
2.98
mg/l
1.22
170
1465
17
102
1.68
1.17
1.7
1.6
—
—
—
0
0
14
235
0.59
1.17
2.1
1.9
—
—
—
0
0
0
33
0.00
1.16
0.0
1.6
—
—
—
0
0
0
33
0.00
1.16
0.0
1.6
—
—
—
0
0
23
151
1.54
1.13
2.2
2.0
3925.52
7179.41
u/l
—
6
53
8
40
2.01
1.12
1.3
1.8
—
—
—
0
0
94
1124
0.81
1.10
1.3
1.3
31.85
34.40
iu/ml
0.08
33
353
5
21
2.39
1.09
1.0
1.2
0.32
0.31
g/l
—
5
16
8
41
1.96
1.09
2.1
1.5
—
—
—
0
0
619
6007
1.22
1.07
31.9
20.4
3.95
3.99
mmol/l
3.03
607
5881
10
52
1.94
1.06
2.4
1.5
—
—
—
0
0
618
6000
1.22
1.04
32.9
20.3
139.63
139.65
mmol/l
0.05
607
5885
69
560
1.26
0.99
3.4
3.1
66.29
66.37
g/l
0.03
63
515
13
76
1.72
0.99
1.2
1.1
—
—
—
0
0
15
93
1.63
0.94
1.7
1.7
—
—
—
0
0
6
120
0.50
0.94
1.2
1.3
—
240.00
—
0
7
10
170
0.58
0.91
1.6
1.2
—
—
—
0
0
40
515
0.76
0.89
2.0
2.0
—
—
—
0
0
8
42
1.91
0.88
1.6
1.2
—
—
—
0
0
8
43
1.87
0.87
2.6
2.6
0.50
0.81
index
—
8
43
6
30
2.01
0.87
2.5
2.2
132.82
69.20
ug/l
—
6
30
50
400
1.27
0.83
1.2
1.2
121.15
161.46
u/ml
0.37
25
157
14
213
0.65
0.82
1.7
1.6
—
—
—
0
0
6
32
1.88
0.82
1.5
3.6
1545.17
892.06
u/ml
—
6
32
129
1455
0.86
0.81
3.5
4.5
20.18
21.79
%
0.57
60
706
485
4656
1.13
0.80
4.6
4.3
15.19
14.84
pmol/l
2.26
447
4236
10
58
1.73
0.80
2.5
1.5
516.60
287.22
mu/l
—
10
46
45
560
0.79
0.79
2.1
2.1
—
—
—
0
0
27
199
1.37
0.79
2.3
3.1
94.63
90.78
%
0.33
27
194
623
6361
0.84
0.79
39.6
25.6
130.06
134.14
g/l
9.69
614
6287
128
1131
1.16
0.79
3.8
3.2
1.33
0.99
e6/l
0.48
86
607
11
66
1.68
0.79
1.4
1.9
—
—
—
0
0
226
2080
1.13
0.76
2.9
3.3
1045.87
1439.95
ng/l
1.04
193
1795
623
6358
0.85
0.76
39.2
25.4
4.35
4.46
e12/l
6.33
610
6211
623
6358
0.85
0.76
39.6
25.9
39.10
40.06
%
5.68
612
6280
64
534
1.22
0.75
3.3
3.9
85.00
83.95
ng/l
0.03
55
473
42
334
1.27
0.75
2.9
3.3
4.56
4.48
pmol/l
0.20
37
294
5
24
2.09
0.74
2.2
5.0
—
—
—
0
0
623
6356
0.85
0.74
39.2
25.4
259.41
248.19
e9/l
3.54
610
6231
623
6356
0.85
0.74
39.1
25.3
90.72
91.12
fl
1.22
612
6284
56
674
0.82
0.74
4.1
4.1
5.51
26.56
ug/l
1.10
48
564
13
85
1.54
0.69
2.3
1.9
32.31
32.54
pg
0.07
13
85
5
92
0.54
0.67
1.0
1.1
—
2.14
—
0
15
72
616
1.19
0.67
1.9
2.4
0.21
0.21
g/l
0.14
64
576
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
12
78
1.55
0.66
1.5
1.2
1.17
2.17
u/ml
—
6
29
12
178
0.67
0.65
1.8
1.9
37.58
41.51
nmol/l
0.23
12
169
155
1410
1.13
0.64
2.0
1.8
2.01
1.36
mg/l
0.51
125
1113
191
2066
0.90
0.63
4.3
4.1
11.41
9.06
mg/mmol
0.21
124
1293
6
104
0.57
0.62
1.0
1.1
—
19.20
—
0
25
131
1447
0.88
0.62
1.3
1.3
1.00
1.87
u/ml
0.98
46
355
29
227
1.29
0.61
2.7
2.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
16.97
—
0
12
298
2821
1.10
0.58
2.7
2.5
75.32
78.01
nmol/l
0.93
275
2527
26
202
1.30
0.58
4.8
4.3
15.97
2.80
ratio
0.42
17
114
23
295
0.77
0.55
1.3
1.3
—
—
—
0
0
67
768
0.86
0.55
2.6
3.0
6.91
7.57
umol/l
0.15
53
685
30
240
1.26
0.54
2.0
1.9
—
—
—
0
0
539
5522
0.90
0.54
22.4
16.4
81.95
78.89
ml/min/173m2
2.40
503
5119
6
38
1.58
0.54
1.5
1.1
—
—
—
0
0
9
62
1.46
0.53
2.1
1.5
—
—
—
0
0
28
223
1.27
0.53
2.0
1.8
—
—
—
0
0
6
39
1.54
0.53
1.3
1.3
—
—
—
0
0
6
39
1.54
0.53
1.3
1.3
—
—
—
0
0
19
248
0.76
0.52
1.1
1.6
0.54
0.34
mg/l
—
6
111
51
595
0.85
0.52
2.8
2.4
28.87
32.70
u/l
0.64
40
487
168
1809
0.91
0.51
4.3
5.5
3.39
2.61
ug/l
0.31
146
1616
112
1018
1.12
0.49
2.8
2.5
2.26
2.29
g/l
0.15
103
948
10
68
1.48
0.47
3.3
1.3
8.59
29.74
u/l
—
10
57
119
1089
1.11
0.46
2.8
2.5
10.94
12.74
umol/l
1.89
109
1016
12
163
0.73
0.44
1.4
1.2
—
—
—
0
0
295
2826
1.07
0.41
2.3
2.2
94.63
95.27
pmol/l
0.09
169
1455
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
25.18
—
0
18
5
35
1.43
0.39
1.0
1.6
—
—
—
0
0
59
526
1.13
0.37
3.1
3.3
168.61
209.68
ng/l
0.43
51
480
5
37
1.35
0.37
1.2
1.6
—
—
—
0
0
5
77
0.65
0.36
1.4
1.3
—
—
—
0
0
5
78
0.64
0.35
1.0
1.1
1.29
1.47
g/l
—
5
69
6
42
1.43
0.35
1.3
1.9
11.87
12.63
umol/l
—
6
37
15
189
0.79
0.34
1.3
1.1
—
—
—
0
0
15
189
0.79
0.34
1.3
1.1
—
—
—
0
0
114
1060
1.09
0.34
4.2
3.3
3.01
2.09
e6/l
0.42
71
532
20
163
1.23
0.34
1.3
1.6
—
—
—
0
0
19
154
1.24
0.34
1.3
1.9
4.47
5.51
iu/l
—
8
58
6
45
1.34
0.34
2.2
2.1
549.17
542.06
e6/l
—
6
31
6
46
1.31
0.33
2.2
2.3
138.00
225.26
e6/l
—
6
35
20
164
1.23
0.33
1.3
1.3
164.57
234.29
miu/ml
—
7
77
75
819
0.91
0.32
1.3
1.4
—
—
—
0
0
146
1547
0.93
0.32
2.8
2.9
332.26
346.61
umol/l
0.92
130
1343
15
186
0.80
0.31
1.2
1.2
—
—
—
0
0
25
212
1.19
0.30
12.5
5.8
1.84
1.47
mg/l
1.02
25
188
7
57
1.23
0.29
2.6
2.4
—
—
—
0
0
208
2167
0.94
0.28
3.6
3.4
7.08
7.48
mmol/l
0.67
182
1833
18
150
1.21
0.26
1.7
1.4
—
—
—
0
0
19
160
1.19
0.25
1.6
1.4
—
—
—
0
0
6
81
0.74
0.24
1.2
1.3
—
—
—
0
0
6
82
0.73
0.24
1.2
1.3
—
—
—
0
0
6
84
0.71
0.24
1.2
1.3
—
—
—
0
0
540
5471
0.95
0.23
5.7
5.4
1.98
1.96
mu/l
0.13
500
5024
27
237
1.14
0.23
3.4
2.6
0.64
0.72
g/l
0.07
21
204
479
4865
0.95
0.22
35.4
22.0
331.67
332.10
g/l
0.44
471
4836
362
3541
1.04
0.22
3.1
3.0
—
—
—
0
0
41
372
1.11
0.22
1.3
1.4
—
36.67
—
0
25
14
116
1.21
0.22
1.4
1.4
175.13
255.46
u/ml
—
8
54
5
41
1.22
0.22
1.4
3.5
1.00
1.05
%
—
5
41
99
936
1.07
0.22
3.0
2.5
19.13
22.52
%
1.73
91
878
378
3857
0.96
0.21
3.5
3.4
52.42
47.71
u/l
0.47
356
3622
5
43
1.16
0.21
1.8
1.6
79.60
80.28
umol/l
—
5
43
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
32.29
—
0
6
0
13
0.00
0.21
0.0
1.0
—
1.73
—
0
6
21
183
1.15
0.20
4.2
3.1
2.70
2.34
index
—
10
96
13
155
0.84
0.20
1.2
1.3
—
—
—
0
0
6
50
1.20
0.19
2.2
3.0
2538.33
1010.56
mg
—
6
50
6
50
1.20
0.19
1.0
1.2
96.17
104.92
pmol/l
—
6
50
7
60
1.17
0.18
1.1
1.4
—
—
—
0
0
7
61
1.15
0.17
1.3
1.2
1.66
1.51
nmol/l
—
7
55
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
8
71
1.13
0.16
1.3
1.3
—
—
—
0
0
6
80
0.75
0.15
1.2
1.3
—
—
—
0
0
6
80
0.75
0.15
1.2
1.3
—
—
—
0
0
69
654
1.06
0.15
1.6
1.8
1.55
1.50
%
0.36
61
575
25
275
0.91
0.14
3.8
1.9
13.08
7.72
iu/ml
—
9
63
98
1017
0.96
0.13
1.6
1.6
—
—
—
0
0
11
127
0.86
0.12
2.1
3.7
28.74
2233.75
u/ml
0.61
11
121
19
208
0.91
0.10
1.1
1.4
349.08
291.54
ug/g
0.92
13
122
5
45
1.11
0.10
1.8
2.4
800.40
555.00
ml
—
5
26
16
176
0.91
0.09
2.1
1.3
—
—
—
0
0
210
2067
1.02
0.08
3.8
3.3
53.91
33.48
u/l
0.45
199
1953
282
2855
0.98
0.08
3.2
3.0
118.59
124.18
ug/l
0.17
250
2642
5
60
0.83
0.08
1.2
1.2
—
—
—
0
0
5
65
0.77
0.08
1.4
1.2
—
79.00
—
0
6
6
71
0.84
0.07
1.0
1.6
—
—
—
0
0
13
143
0.91
0.07
2.1
2.5
112.04
87.51
ug/min
—
8
88
7
84
0.83
0.07
1.4
1.3
—
—
—
0
0
30
316
0.95
0.07
1.0
1.0
—
—
—
0
0
22
206
1.07
0.07
1.5
1.5
0.00
0.04
iu/ml
—
6
34
13
142
0.91
0.06
3.5
3.4
0.85
0.85
nmol/l
0.02
13
116
22
207
1.06
0.06
1.5
2.4
0.00
0.00
g/l
-0.00
17
180
620
6184
1.02
0.04
31.9
22.1
74.64
77.98
umol/l
1.77
610
6108
15
159
0.94
0.03
1.1
1.1
—
13.19
—
0
16
450
4514
0.99
0.02
4.3
4.5
14.59
12.56
mm/h
1.80
419
4183
25
242
1.03
0.02
1.6
2.3
9.46
10.18
g/l
0.56
20
216
25
242
1.03
0.02
1.3
1.2
0.30
1.94
u/ml
—
6
15
356
3572
0.99
0.02
13.1
9.5
4.42
4.16
e9/l
1.03
325
3105
20
196
1.02
0.00
1.3
1.2
—
—
—
0
0
10
102
0.98
0.00
1.3
1.3
—
—
—
0
0
31
313
0.99
0.00
3.6
2.9
43.44
100.43
u/ml
0.77
31
301
15
152
0.99
0.00
1.1
1.1
—
4.36
—
0
19
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
0.03
—
0
9
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
5.97
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.9
—
55.34
—
0
7
6
63
0.95
-0.00
1.2
1.6
—
—
—
0
0
6
68
0.88
-0.00
1.7
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.6
1.1
—
—
—
0
0
6
60
1.00
-0.00
2.0
1.2
3650.67
147006.14
e6/l
—
6
42
5
54
0.93
-0.00
1.2
1.5
61.65
53.56
ug/l
—
5
54
6
63
0.95
-0.00
1.2
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.6
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
5
54
0.93
-0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_HCOTHUNS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCOTHUNS | 3.018 [2.63, 3.46] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.569 |
During the follow-up period (1.1.1998 — 31.12.2019), 789 out of 2228 females with G6_HCOTHUNS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCOTHUNS | 3.131 [2.67, 3.68] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 826 out of 2254 males with G6_HCOTHUNS died.
Mortality risk
Mortality risk for people of age
years, who have G6_HCOTHUNS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.299% | 0.595% |
| 5 | 2.223% | 3.345% |
| 10 | 5.219% | 8.599% |
| 15 | 10.012% | 15.221% |
| 20 | 16.312% | 24.269% |
Relationships between endpoints
↥Index endpoint: G6_HCOTHUNS – Other and unspecified hydrocephalus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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