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This is a non-core endpoint: only basic statistics are computed.

Need for immunization against certain single viral diseases

Z21_NEED_IMMUNI_CERTA_SINGLE_VIRAL_DISEA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z24
  • Cause of death: ICD-10 Z24

2 out of 7 registries used, show all original rules.

76

4. Check minimum number of events

None

76

5. Include endpoints

None

76

6. Filter based on genotype QC (FinnGen only)

67

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_COMMUNICAB_DISEA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 67 52 15
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 39.05 39.12 38.82

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
72
Matched controls
720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z24.2
ICD-10 Finland
Need for immunization against rabies
+∞
39.2
34
*
Z24.4
ICD-10 Finland
Need for immunization against measles alone
+∞
11.8
11
*
Z24.0
ICD-10 Finland
Need for immunization against poliomyelitis
+∞
8.5
8
*
Z20.3
ICD-10 Finland
Contact with and exposure to rabies
+∞
7.4
7
*
Z24.6
ICD-10 Finland
Need for immunization against viral hepatitis
22.8
7.4
10
5

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
12
5.34
2.45
1.5
2.3
—
—
—
0
0
27
158
2.13
2.33
3.1
2.6
—
—
estimate
—
0
0
12
51
2.62
2.08
7.8
10.6
1.09
1.06
mmol/l
0.13
12
45
6
16
3.99
1.98
1.5
2.2
472.00
313.44
mg/l
—
6
16
6
16
3.99
1.98
1.3
1.3
—
—
—
0
0
26
159
1.99
1.95
3.3
2.7
0.26
0.37
e6/l
0.22
20
107
33
220
1.92
1.93
4.2
3.4
26.97
22.25
e6/l
0.10
25
138
28
178
1.94
1.87
3.1
2.9
15.60
26.96
e6/l
0.58
20
129
28
181
1.90
1.77
6.1
6.9
—
—
—
0
0
30
199
1.87
1.75
1.5
1.4
0.69
0.69
u/ml
0.00
12
43
6
19
3.35
1.70
2.0
5.7
24.17
24.73
mmol/l
—
6
19
30
201
1.84
1.68
1.8
2.3
—
—
—
0
0
28
189
1.79
1.51
3.1
2.8
0.00
0.02
estimate
—
8
50
6
22
2.88
1.46
2.2
4.8
—
—
—
0
0
17
100
1.92
1.39
1.7
1.5
—
—
—
0
0
9
43
2.25
1.36
1.0
1.1
—
—
—
0
0
35
259
1.68
1.33
2.9
2.9
6.53
6.25
ph
0.51
17
150
24
160
1.75
1.32
2.4
3.2
7.41
7.39
ph
0.80
17
114
9
44
2.19
1.32
2.1
1.2
—
—
—
0
0
43
337
1.69
1.31
10.4
7.3
2.28
1.91
e9/l
1.51
38
310
29
206
1.68
1.27
13.1
6.8
—
—
—
0
0
67
608
2.47
1.26
16.1
13.9
139.69
139.74
mmol/l
0.07
67
597
67
607
2.49
1.26
16.3
13.9
3.87
3.92
mmol/l
0.64
67
594
8
38
2.24
1.23
1.4
1.4
—
—
—
0
0
5
20
2.61
1.17
1.2
1.6
0.33
0.50
nmol/l
—
5
14
5
21
2.48
1.11
1.6
1.7
—
—
—
0
0
25
177
1.63
1.09
1.3
1.4
2.06
2.29
g/l
0.32
12
102
7
34
2.17
1.06
2.0
1.6
—
—
—
0
0
41
329
1.57
1.05
3.8
3.4
0.00
0.00
estimate
—
9
71
10
54
1.99
1.02
1.8
1.5
—
—
—
0
0
41
331
1.55
1.01
4.0
3.5
0.00
0.00
estimate
—
8
68
33
256
1.53
0.96
2.6
1.9
—
—
—
0
0
12
71
1.83
0.96
1.5
1.2
—
—
—
0
0
40
325
1.52
0.93
3.9
3.4
0.00
0.00
estimate
—
9
71
26
193
1.54
0.91
10.0
9.7
1.25
1.11
inr
0.55
19
166
45
376
1.52
0.91
12.5
10.0
4.23
3.81
e9/l
0.52
39
326
8
43
1.97
0.91
4.3
3.2
—
—
—
0
0
18
123
1.62
0.88
4.6
4.1
—
—
—
0
0
13
83
1.69
0.82
1.2
2.8
—
—
—
0
0
22
161
1.53
0.81
1.7
1.7
—
—
—
0
0
34
273
1.47
0.81
15.3
10.9
0.00
0.00
e9/l
-0.00
27
212
11
67
1.76
0.80
1.2
1.4
—
—
—
0
0
29
227
1.46
0.78
2.9
1.9
96.06
96.32
pmol/l
0.01
17
110
7
38
1.93
0.76
2.3
1.9
—
—
—
0
0
14
94
1.61
0.73
4.2
2.2
2.43
2.44
mmol/l
0.26
14
84
23
174
1.47
0.72
3.4
3.5
0.00
0.00
estimate
—
8
66
5
26
1.99
0.72
2.2
1.3
—
—
—
0
0
17
124
1.49
0.63
1.9
1.7
—
—
—
0
0
10
64
1.65
0.62
2.2
2.1
—
—
—
0
0
72
699
+∞
0.61
25.3
19.3
263.40
263.37
e9/l
0.00
72
688
35
294
1.37
0.60
2.5
3.1
—
—
estimate
—
0
0
11
73
1.60
0.60
1.2
1.6
—
—
—
0
0
20
153
1.43
0.59
1.7
1.9
1.27
1.17
mg/l
0.06
15
111
22
174
1.38
0.54
2.5
2.3
—
—
—
0
0
30
251
1.33
0.51
3.4
3.2
0.00
0.00
estimate
—
7
56
7
46
1.58
0.50
1.9
1.4
—
—
—
0
0
26
214
1.34
0.49
1.7
1.6
—
—
—
0
0
38
331
1.31
0.49
11.4
7.3
0.05
0.04
e9/l
1.59
32
296
38
331
1.31
0.49
11.5
7.3
0.60
0.55
e9/l
0.48
32
296
5
31
1.66
0.44
1.8
1.3
4.24
14.29
u/l
—
5
23
0
16
0.00
0.41
0.0
5.8
—
—
—
0
0
72
702
+∞
0.40
25.3
19.3
134.07
135.35
g/l
0.44
72
694
9
67
1.39
0.40
2.4
1.3
—
—
—
0
0
72
701
+∞
0.39
25.0
19.2
89.81
90.16
fl
0.28
72
694
72
701
+∞
0.39
25.1
19.1
29.98
30.10
pg
0.22
72
693
0
19
0.00
0.39
0.0
2.8
—
36.86
—
0
19
6
41
1.50
0.37
17.0
21.0
4.72
5.02
kpa
—
6
41
6
41
1.50
0.37
17.0
21.1
11.07
13.54
kpa
—
6
41
22
187
1.25
0.32
5.4
2.8
12.84
31.98
ng/l
0.71
12
102
7
54
1.33
0.31
1.9
1.5
—
—
—
0
0
13
103
1.32
0.31
3.2
2.7
5.88
96.17
ng/l
—
8
58
7
56
1.28
0.30
1.9
1.4
—
—
—
0
0
10
77
1.35
0.28
1.4
1.4
—
—
—
0
0
19
162
1.23
0.26
2.9
2.0
134.58
116.45
u/l
0.26
19
157
5
37
1.38
0.24
17.8
8.0
0.94
1.15
mmol/l
—
5
37
5
37
1.38
0.24
20.2
23.1
96.44
96.02
%
—
5
37
5
38
1.34
0.24
14.8
10.1
—
—
—
0
0
5
38
1.34
0.24
1.4
1.6
—
—
—
0
0
19
165
1.21
0.22
4.7
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
308.91
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
0.47
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
9.05
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
25.19
—
0
12
6
51
1.19
0.20
1.3
1.4
—
—
—
0
0
7
57
1.25
0.19
1.9
1.4
—
—
—
0
0
7
57
1.25
0.19
1.9
1.4
—
—
—
0
0
7
57
1.25
0.19
1.9
1.4
—
—
—
0
0
29
266
1.15
0.18
2.8
2.9
—
—
—
0
0
46
436
1.15
0.17
5.7
4.0
—
—
—
0
0
10
84
1.22
0.15
1.2
1.2
—
—
—
0
0
8
96
0.81
0.15
1.3
1.3
—
—
—
0
0
20
185
1.11
0.09
2.3
2.1
—
—
—
0
0
16
146
1.12
0.09
2.0
3.1
1.01
1.02
kg/l
0.51
11
93
6
73
0.81
0.08
1.2
1.2
—
—
—
0
0
12
132
0.89
0.07
1.5
1.6
—
—
—
0
0
14
151
0.91
0.06
3.9
3.5
106.39
55.78
mg/l
—
8
98
61
620
0.89
0.05
17.7
12.8
14.00
19.45
mg/l
2.05
53
478
15
153
0.98
0.00
5.1
4.1
6.49
7.85
mg/mmol
—
9
96
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
85.63
—
0
9
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
2.6
—
3.82
—
0
9
6
65
0.92
0.00
2.5
1.6
—
0.00
estimate
—
0
12
0
9
0.00
0.00
0.0
3.7
—
11.57
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
4.05
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
10.20
—
0
5
17
170
1.00
-0.00
6.8
5.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
24.3
—
1406.29
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
1.20
—
0
8
0
8
0.00
-0.00
0.0
2.9
—
103.50
—
0
8
0
7
0.00
-0.00
0.0
23.1
—
840.57
—
0
7
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_NEED_IMMUNI_CERTA_SINGLE_VIRAL_DISEA – Need for immunization against certain single viral diseases

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).