Hirsutism, drug-induced

L12_HIRSUTISM_ADVERSE

Excess hair growth or hair growth where hair is usually sparse.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ATC codes for adverse effects of Drugs — ANY Hospital discharge: ICD-10 — L68.0# 1 out of 7 registries used, show all original rules.	76
4. Check minimum number of events None	76
5. Include endpoints None	76
6. Filter based on genotype QC (FinnGen only)	62

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5
Parent code in ICD-10: L68
Name in latin: Hirsutismus

NAME	L12_HIRSUTISM_ADVERSE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC	ANY
HD_ICD_10	L680
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hirsutism, drug-induced based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	62	62	-
Unadjusted period prevalence (%)	0.02	0.02	-
Median age at first event (years)	32.95	32.95	-

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
67: Matched controls
670

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L68.0

ICD-10 Finland

Hirsutism

+∞

91.5

G03HB01

ATC

cyproterone and estrogen; oral

10.2

21.1

G03DB01

ATC

dydrogesterone; oral

5.5

11.1

105

C03DA01

ATC

spironolactone; oral

10.4

10.9

T90

ICPC

Diabetes non-insulin dependent

4.9

8.4

XLA10, ,

NOMESCO Finland

9.1

8.1

215

Kela drug reimbursment

Diabetes, non-insulin-treated

4.7

7.9

103

Kela drug reimbursment

Diabetes, insulin-treated

4.6

7.7

G03HA01

ATC

cyproterone; systemic

+∞

7.4

E28.2

ICD-10 Finland

Polycystic ovarian syndrome

16.1

7.2

A10BA02

ATC

metformin; oral

4.0

6.7

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3012516) Albumin [Mass/volume] in Urine

142

2.84

4.07

3.6

2.9

8.89

27.37

mg/l

0.98

(3020682) Albumin/Creatinine [Ratio] in Urine

142

2.84

4.07

4.2

3.3

1.43

5.03

mg/mmol

0.71

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

2.80

0.0

4.1

—

32.45

—

(4034850) Laboratory test

4.47

2.43

5.3

6.4

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

3.80

2.35

1.0

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

3.80

2.35

1.0

1.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

3.64

2.26

1.0

1.3

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.34

2.21

2.5

2.9

6.60

205.06

ng/l

—

(3018418) pH of Serum or Plasma

167

2.03

2.00

4.6

3.1

7.43

7.40

2.59

112

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

2.55

1.82

5.5

4.4

4.36

4.53

pmol/l

0.31

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

3.13

1.77

1.6

1.5

—

(3025941) Bacteria identified in Stool by Culture

2.69

1.73

1.3

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.69

1.73

1.1

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

181

1.82

1.51

5.6

2.7

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

284

1.78

1.47

1.9

1.8

1.79

1.35

mmol/l

1.74

250

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.29

1.46

2.2

1.4

60.20

93.25

ng/l

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

1.39

0.0

1.5

—

295.77

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

242

1.72

1.33

2.3

1.8

91.00

101.93

pmol/l

0.67

135

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

152

1.78

1.33

2.0

1.8

0.58

1.16

mg/l

0.70

125

(3015377) Calcium [Moles/volume] in Serum or Plasma

217

1.69

1.25

3.8

3.1

2.37

2.36

mmol/l

0.20

206

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

1.20

0.0

1.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.13

1.18

2.6

1.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

203

1.65

1.14

2.4

3.2

8.33

17.05

ng/l

2.31

103

(3019198) Lymphocytes [#/volume] in Blood

329

1.63

1.10

4.1

5.0

2.04

1.90

e9/l

0.48

293

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.25

1.09

1.3

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

171

1.63

1.03

2.2

3.3

—

(3045424) Erythrocytes [Presence] in Urine

0.00

1.00

0.0

1.6

—

0.00

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.96

0.98

2.6

1.3

—

(3013512) EKG study

175

0.56

0.96

1.9

2.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

165

1.60

0.95

1.5

1.4

8.63

27.86

iu/ml

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

176

1.57

0.90

1.5

1.3

2.54

1.85

u/ml

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.88

0.88

1.8

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

152

1.56

0.83

1.5

23.81

20.65

nmol/l

0.48

136

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

469

1.62

0.81

7.8

7.5

75.38

76.72

u/l

0.15

438

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

154

1.53

0.78

1.4

1.11

10.24

u/ml

1.37

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.17

0.76

1.4

2.3

—

(3031040) Bacteria [#/volume] in Urine by Automated count

387

1.50

0.76

5.6

4.3

—

677.00

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.89

0.75

1.7

1.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.08

0.74

1.4

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

129

0.57

0.73

1.1

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.63

0.68

2.3

1.5

—

(3003694) ABO and Rh group [Type] in Blood

183

0.64

0.68

1.6

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

189

1.42

0.62

1.9

2.8

0.00

estimate

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.61

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.61

0.0

1.1

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

0.61

0.0

2.2

—

3.33

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

146

0.63

0.61

2.8

2.2

—

(3035350) Ketones [Presence] in Urine by Test strip

325

1.39

0.60

3.0

3.6

0.00

estimate

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.59

0.57

1.3

1.5

—

(3002256) Pathology report gross observation

0.57

1.0

1.2

—

(40768797) Stomach Pathology biopsy report

1.54

0.56

1.7

1.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

292

0.72

0.56

3.2

2.7

—

estimate

—

(42870588) Differential panel, method unspecified - Blood

192

1.39

0.56

4.5

4.6

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

119

1.45

0.55

2.4

2.44

2.43

mmol/l

0.02

109

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

467

1.39

0.47

4.3

3.2

41.86

37.18

u/l

0.33

453

(3021601) Nitrite [Presence] in Urine by Test strip

324

1.32

0.46

3.1

3.5

0.00

estimate

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.63

0.46

1.0

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

191

0.72

0.45

2.5

2.3

—

(3021589) Normoblasts [#/volume] in Blood

286

1.30

0.44

7.2

8.8

0.00

e9/l

0.86

227

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

1.56

0.42

1.8

1.1

0.78

0.85

g/l

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

317

1.29

0.42

5.4

4.2

7.03

6.22

mmol/l

1.63

293

(3035933) Granulocytes/Leukocytes in Blood

0.00

0.42

0.0

1.9

—

63.10

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.41

0.0

1.5

—

(40758558) Short blood count panel - Blood

172

1.32

0.41

8.0

6.2

—

(3022313) Gas panel - Capillary blood

0.00

0.41

0.0

3.2

—

(3026008) Bacteria identified in Urine by Culture

173

1.31

0.39

2.5

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.33

0.39

2.7

2.3

22.56

24.51

—

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

1.43

0.37

2.1

1.9

3.48

3.65

mmol/l

—

(40768804) Tissue Pathology biopsy report

268

0.78

0.36

2.4

2.0

—

(3008898) HLA-B27 [Presence]

1.40

0.35

1.0

1.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.28

0.30

9.1

7.2

105.57

104.25

mmol/l

—

(3000494) Fungus identified in Specimen by Culture

0.66

0.27

1.0

1.3

—

(3000492) Spirometry study

1.21

0.26

2.1

1.4

—

(21494755) Public health laboratory ask at order entry panel

1.33

0.26

1.1

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

103

0.75

0.23

1.9

1.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

154

0.81

0.22

2.0

1.4

2.27

2.48

g/l

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.0

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.21

0.0

1.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.21

0.0

1.3

—

46.00

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3010421) pH of Blood

0.00

0.21

0.0

2.1

—

7.43

—

(3026361) Erythrocytes [#/volume] in Blood

658

+∞

0.21

23.1

19.8

4.65

4.46

e12/l

4.31

652

(3010813) Leukocytes [#/volume] in Blood

658

+∞

0.21

23.1

19.9

7.32

6.50

e9/l

2.75

652

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.27

0.21

1.5

—

(3007461) Platelets [#/volume] in Blood

657

+∞

0.21

23.1

19.9

276.54

268.15

e9/l

0.55

652

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

1.3

—

48.59

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.21

0.0

3.5

—

25.09

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3015736) pH of Urine

254

1.18

0.21

2.9

3.3

6.23

6.21

0.03

143

(44806420) Estimation of glomerular filtration rate

0.00

0.20

0.0

2.6

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.6

—

59.18

—

(3019150) Specific gravity of Urine by Refractometry

138

1.21

0.20

3.9

3.7

1.01

1.02

kg/l

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

345

1.16

0.19

4.1

3.3

89.76

68.24

ug/l

0.53

327

(36660697) Celiac disease serology panel - Serum

1.23

0.19

1.6

1.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.14

0.18

2.0

1.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.75

0.18

1.0

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

159

1.18

0.17

1.9

1.7

—

(3017732) Neutrophils [#/volume] in Blood

0.74

0.16

3.2

3.37

4.64

e9/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

408

1.15

0.16

4.2

4.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

138

0.84

0.14

1.8

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

172

1.15

0.13

1.4

1.5

—

(3023368) Bacteria identified in Blood by Culture

125

1.15

0.11

4.2

3.8

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.18

0.10

1.0

—

(1002224) Polysomnography panel

1.12

0.10

1.2

1.1

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

334

1.10

0.09

7.1

6.1

8.44

9.14

umol/l

0.45

317

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

107

1.15

0.09

2.3

2.0

3.43

3.31

ratio

0.15

(3019832) Treponema pallidum Ab [Presence] in Serum

0.79

0.08

2.2

1.8

—

(3042936) Bacteria identified in Isolate by Culture

1.11

0.08

1.5

2.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.83

0.07

2.0

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.85

0.07

1.9

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

174

1.05

0.00

3.9

0.00

estimate

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

474

1.04

0.00

3.2

3.6

—

(1761868) Lipid panel - Serum or Plasma

305

1.03

0.00

3.3

2.7

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.5

—

2.16

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.1

—

0.89

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

5.72

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

-0.00

0.0

2.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

92.43

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

17.66

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.1

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

7.0

—

18.00

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.2

—

55.20

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3035715) Granulocytes [#/volume] in Blood

0.00

-0.00

0.0

1.9

—

6.82

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

6.99

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.8

—

6.95

—

(3023419) Bacteria identified in Sputum by Culture

0.00

-0.00

0.0

2.2

—

(3034426) Prothrombin time (PT)

0.00

-0.00

0.0

1.2

—

29.40

—

(3022145) Colonoscopy Study observation

0.91

-0.00

1.4

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3015183) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells

0.00

-0.00

0.0

1.0

—

8.29

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

1.2

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

2.0

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

2.3

—

4.84

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.6

—

8.52

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.6

—

360.00

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

1.4

—

7.86

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

601

1.17

-0.00

14.4

13.0

14.02

18.36

mg/l

0.92

473

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

2.3

—

9.88

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

466.60

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

221.20

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

31.20

—

(40761536) Microorganisms panel - Urine sediment

0.96

-0.00

3.0

2.8

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

2.26

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.3

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

↥

Index endpoint: L12_HIRSUTISM_ADVERSE – Hirsutism, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Hirsutism, drug-induced

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Hirsutism, drug-induced (L12_HIRSUTISM_ADVERSE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints