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Aspergillosis

EFO Endpoint Browser PheWeb

AB1_ASPERGILLOSIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B44
  • Hospital discharge: ICD-9 — 1173
  • Hospital discharge: ICD-8 — 1173
  • Cause of death: ICD-10 — B44
  • Cause of death: ICD-9 — 1173
  • Cause of death: ICD-8 — 1173

2 out of 7 registries used, show all original rules.

327

4. Check minimum number of events

None

327

5. Include endpoints

None

327

6. Filter based on genotype QC (FinnGen only)

312

Control definitions (FinnGen only)

Control exclude
AB1_MYCOSES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1897 694 1166
Only index persons 1320 508 812
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 62.18 61.22 62.71
Only index persons 62.61 60.94 63.65

-FinnGen-

Key figures

All Female Male
Number of individuals 312 120 192
Unadjusted period prevalence (%) 0.07 0.04 0.09
Median age at first event (years) 64.10 59.62 66.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
327
Matched controls
3270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
167.5
146
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
18.3
146.8
148
141
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
20.2
137.8
124
96
J02AC03
ATC
voriconazole; systemic
407.5
134.0
126
5
TGC00
NOMESCO Finland
Bronchial lavation
24.8
128.6
100
57
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
11.3
102.2
144
213
J01MA14
ATC
moxifloxacin; systemic
10.4
87.9
125
184
R03BB04
ATC
tiotropium bromide; inhalant
9.3
81.0
128
212
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
80.6
74
*
GD1AD
NOMESCO Finland
Thorax CT examination
11.3
80.2
100
123
J18.9
ICD-10 Finland
Pneumonia, unspecified
8.2
80.0
216
626
J47
ICD-10 Finland
Bronchiectasis
23.3
76.4
58
30
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.2
69.5
84
98
R04.2
ICD-10 Finland
Haemoptysis
16.8
69.2
62
45
B44.9
ICD-10 Finland
Aspergillosis, unspecified
+∞
67.0
62
*
B44.8
ICD-10 Finland
Other forms of aspergillosis
773.7
66.4
63
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
8.4
64.5
103
169
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
15.4
64.0
60
47
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
14.0
64.0
64
56
127
Kela drug reimbursment
Transplant complication
31.1
61.1
41
15
J45.0
ICD-10 Finland
Predominantly allergic asthma
7.7
52.6
88
150
J01MA12
ATC
levofloxacin; systemic
5.7
52.5
150
426
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
5.4
49.2
144
414
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.2
45.2
260
1262
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
+∞
43.7
41
*
H02AB06
ATC
prednisolone; systemic
5.4
42.5
247
1185
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
40.7
127
377
R03AK08
ATC
formoterol and beclometasone; inhalant
9.2
40.4
53
67
J45.9
ICD-10 Finland
Asthma, unspecified
4.8
40.3
128
385
J45.1
ICD-10 Finland
Nonallergic asthma
6.9
40.3
71
126
R03DC03
ATC
montelukast; oral
5.1
39.3
108
288
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.9
38.8
113
316
XG410
NOMESCO Finland
Flow-volume spirometry
8.6
36.7
51
69
L03AA02
ATC
filgrastim; parenteral
10.0
36.3
44
50
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.4
35.5
57
91
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.4
35.4
50
69
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.9
34.4
59
101
H02AB04
ATC
methylprednisolone; systemic
4.6
33.7
102
291
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.4
33.6
63
118
R81
ICPC
Pneumonia
8.6
32.2
44
58
R03AC12
ATC
salmeterol; inhalant
7.1
31.6
52
85
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.9
30.2
79
199
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.3
30.0
56
104
R50.9
ICD-10 Finland
Fever, unspecified
4.2
28.9
100
312
XW000
NOMESCO Finland
Bone marrow biopsy
7.1
28.7
47
76
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.4
28.0
35
41
J46
ICD-10 Finland
Status asthmaticus
12.1
27.9
29
26
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.8
27.7
231
1270
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
27.2
62
138
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.5
27.2
80
220
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
26.4
87
260
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6.1
26.3
50
94
H02AB07
ATC
prednisone; oral
4.2
26.2
84
246
J02AC05
ATC
isavuconazole; systemic
269.8
25.0
25
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
24.8
85
261
R03DA04
ATC
theophylline; systemic, rectal
5.6
24.1
50
102
R03AC13
ATC
formoterol; inhalant
6.1
23.6
44
81
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
8.3
23.4
32
42
R03BA01
ATC
beclometasone; inhalant
4.0
23.1
79
241
J02AC04
ATC
posaconazole; systemic
246.6
22.9
23
*
WW500
NOMESCO Finland
Blood transfusion
6.5
22.9
40
69
R03BA05
ATC
fluticasone; inhalant
3.5
22.3
98
354
J45.8
ICD-10 Finland
Mixed asthma
8.5
21.6
29
37
H02AB09
ATC
hydrocortisone; systemic
8.2
21.6
30
40
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
82.3
21.0
23
*
WW200
NOMESCO Finland
Immunization
9.3
20.9
26
30
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.3
20.3
31
46
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
6.8
20.1
33
53
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
20.1
154
761
J17.2*B44.1
ICD-10 Finland
Pneumonia in other aspergillosis
+∞
20.0
19
*
JN4BD
NOMESCO Finland
Extensive body CT
3.9
20.0
70
216
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
8.1
19.4
27
36
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.6
19.4
51
127
WX892
NOMESCO Finland
Monitored bed care
4.6
19.4
51
127
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
5.9
19.0
36
67
GDC00
NOMESCO Finland
Lobectomy of lung
74.4
18.9
21
*
J17.2*B44.0
ICD-10 Finland
Pneumonia in invasive aspergillosis
+∞
18.9
18
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.1
18.8
43
95
J01FA06
ATC
roxithromycin; oral
2.8
18.8
174
942
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.3
18.3
39
81
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
28.6
18.1
24
9
A07AA02
ATC
nystatin; oral
5.3
17.8
38
79
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.3
17.6
50
132
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.0
17.3
32
58
L04AA06
ATC
mycophenolic acid; systemic
14.3
17.3
29
22
R03AC02
ATC
salbutamol; inhalant
2.8
17.2
217
1354
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.6
17.1
34
66
L04AD02
ATC
tacrolimus; systemic
23.4
17.1
24
11
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.3
17.0
48
126
49300
ICD-8 Finland
Asthma, bronchiale
7.2
16.8
26
39
R03AK11
ATC
formoterol and fluticasone; inhalant
7.2
16.8
26
39
A04AA01
ATC
ondansetron; systemic, rectal
4.0
16.8
52
146
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.0
16.6
98
413
J01FF01
ATC
clindamycin; systemic
2.8
16.5
121
573
J45
ICD-10 Finland
Asthma
3.8
16.5
57
173
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
13.8
16.5
28
22
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
16.2
116
541
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
16.0
110
502
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.3
15.9
24
35
J01FA09
ATC
clarithromycin; systemic
2.6
15.4
129
649
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
6.7
15.2
25
40
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.3
15.0
26
44
JN4CD
NOMESCO Finland
Very extensive body CT
5.7
14.9
29
55
Z2446
NOMESCO Finland
Social worker
4.4
14.8
40
101
JN4AD
NOMESCO Finland
Body CT examination
3.2
14.6
69
255
R03AK07
ATC
formoterol and budesonide; inhalant
2.8
14.5
93
407
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.6
14.4
24
39
ZX120
NOMESCO Finland
Intravenous
3.4
14.4
57
189
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
14.3
94
417
J96.1
ICD-10 Finland
Chronic respiratory failure
7.1
14.2
22
33
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.7
14.1
98
446
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
25.1
13.9
19
8
J01FA15
ATC
telithromycin; oral
3.5
13.9
53
171
L04AD01
ATC
ciclosporin; systemic
12.9
13.8
24
20
J01FA10
ATC
azithromycin; systemic
2.5
13.8
205
1324
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
19.3
13.5
20
11
J02AC02
ATC
itraconazole; systemic
2.9
13.5
77
316
J01AA02
ATC
doxycycline; systemic
3.2
13.1
279
2115
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
6.5
13.1
22
36
R03BA08
ATC
ciclesonide; inhalant
3.6
12.9
47
147
A02BC02
ATC
pantoprazole; systemic
2.7
12.8
254
1844
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.3
12.8
35
89
XG474
NOMESCO Finland
Exhalation nntrogen oxide
6.0
12.6
23
41
J01GB01
ATC
tobramycin; inhalant, parenteral
135.0
12.5
13
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
12.4
161
965
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
12.3
124
666
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
16.7
12.3
19
12
R03BA02
ATC
budesonide; inhalant
2.6
12.1
84
379
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.9
12.1
38
107
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
12.1
85
386
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
12.1
60
227
ZXD05
NOMESCO Finland
Urgent procedure
2.4
11.8
118
630
R06.0
ICD-10 Finland
Dyspnoea
2.4
11.8
119
638
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
67.4
11.7
13
*
A05AA02
ATC
ursodeoxycholic acid; oral
10.6
11.2
21
21
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.7
11.0
21
39
Z94.2
ICD-10 Finland
Lung transplant status
44.9
11.0
13
*
M05BA04
ATC
alendronic acid; oral
3.5
11.0
41
130
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
10.9
75
336
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.3
10.9
44
147
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.5
10.8
27
64
ZX112
NOMESCO Finland
Subcutaneous
5.5
10.7
21
40
J02AC01
ATC
fluconazole; systemic
2.2
10.7
127
724
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
113.5
10.5
11
*
J05AB11
ATC
valaciclovir; oral
2.6
10.5
69
302
B44.7
ICD-10 Finland
Disseminated aspergillosis
+∞
10.5
10
*
C03CA01
ATC
furosemide; systemic
2.2
10.4
130
754
SPAT1255
SPAT
Intravenous administration of medicine
3.7
10.3
34
99
R4110
NOMESCO Finland
Physiotherapy
2.2
10.2
113
625
R03AC03
ATC
terbutaline; inhalant
2.8
10.1
58
236
ZX108
NOMESCO Finland
Inhalation
15.2
10.1
16
11
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
10.1
92
468
R4190
NOMESCO Finland
Nutritional therapy
4.6
10.0
24
55
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.4
9.9
37
117
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.7
9.9
33
97
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
9.8
72
331
L03AA13
ATC
pegfilgrastim; parenteral
4.1
9.6
27
70
B02AA02
ATC
tranexamic acid; systemic
2.8
9.5
53
213
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
9.4
9
*
R03BB01
ATC
ipratropium bromide; inhalant
4.1
9.3
26
67
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
14.2
9.3
15
11
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
5.2
9.2
19
38
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
11.9
9.2
16
14
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.3
9.1
24
59
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
9.1
23
55
Z3226
NOMESCO Finland
Physiotherapist
2.4
9.1
75
364
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
19.3
9.0
13
7
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
13.0
9.0
15
12
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.1
8.8
105
591
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
14.6
8.8
14
10
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.6
8.7
21
48
GDG10
NOMESCO Finland
Bilateral transplantation of lung
51.4
8.7
10
*
J85.2
ICD-10 Finland
Abscess of lung without pneumonia
51.4
8.7
10
*
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
5.0
8.7
19
40
UDM02
NOMESCO Finland
Sinoscopy
6.7
8.6
21
33
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
16.8
8.6
13
8
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
28.4
8.5
11
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
8.5
82
424
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
92.3
8.5
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
8.4
85
447
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
+∞
8.4
8
*
R01AD09
ATC
mometasone; nasal
2.0
8.4
155
1022
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.8
8.3
45
177
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
8.3
45
177
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.4
8.3
31
98
WX872
NOMESCO Finland
Intensive care
3.5
8.3
30
93
J01DB01
ATC
cefalexin; oral
2.5
8.3
280
2295
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
15.0
8.3
13
9
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.1
8.3
35
120
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.1
8.2
19
28
RS220, ,
NOMESCO Finland
17.7
8.1
12
7
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
34.3
8.1
10
*
N02AA05
ATC
oxycodone; systemic
2.2
8.1
81
424
J98.1
ICD-10 Finland
Pulmonary collapse
22.7
8.1
11
5
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.9
8.0
19
29
Z2221
NOMESCO Finland
Medical doctor
2.1
8.0
98
556
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.0
7.9
23
61
H60.8
ICD-10 Finland
Other otitis externa
4.2
7.9
21
52
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
7.9
52
226
R01AD08
ATC
fluticasone; nasal
2.1
7.9
102
590
A41.9
ICD-10 Finland
Sepsis, unspecified
4.1
7.8
22
57
M04AA01
ATC
allopurinol; systemic
2.4
7.8
62
294
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.3
7.8
31
102
J01CA04
ATC
amoxicillin; systemic
2.3
7.8
272
2220
L01BB05
ATC
fludarabine; systemic
46.1
7.7
9
*
5BA08, ,
NOMESCO Finland
46.1
7.7
9
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.6
7.7
26
77
R06.2
ICD-10 Finland
Wheezing
4.0
7.7
22
58
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
18.9
7.6
11
6
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
12.2
7.6
13
11
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
25.7
7.6
10
*
XX2RW, ,
NOMESCO Finland
10.4
7.6
14
14
R03DC01
ATC
zafirlukast; oral
7.4
7.6
17
24
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.5
158
1078
N03AX16
ATC
[U] pregabalin
2.1
7.4
87
483
A02BC01
ATC
omeprazole; systemic
2.0
7.4
98
570
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.3
7.4
19
46
R06AE07
ATC
cetirizine; oral
1.9
7.4
139
912
A10AC01
ATC
insulin (human); parenteral
2.9
7.4
37
140
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
20.6
7.2
10
5
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
9.1
7.1
14
16
J43.9
ICD-10 Finland
Emphysema, unspecified
6.1
7.0
18
31
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
7.8
7.0
15
20
AA1AD
NOMESCO Finland
CT of head and brain
1.9
7.0
111
686
WX600
NOMESCO Finland
Single shot through catheter
14.2
6.9
11
8
J32.4
ICD-10 Finland
Chronic pansinusitis
8.5
6.9
14
17
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
9.6
6.8
13
14
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
6.8
23
68
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
17.1
6.8
10
6
Z94.0
ICD-10 Finland
Kidney transplant status
17.1
6.8
10
6
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.7
6.7
16
25
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.6
6.6
11
9
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
7.1
6.6
15
22
J96.0
ICD-10 Finland
Acute respiratory failure
10.3
6.6
12
12
M05BA07
ATC
risedronic acid; oral
5.5
6.6
18
34
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
6.6
27
91
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
6.4
6.6
16
26
B03XA02
ATC
darbepoetin alfa; parenteral
6.4
6.6
16
26
A10AB05
ATC
insulin aspart; parenteral
2.7
6.5
36
143
H60
ICD-10 Finland
Otitis externa
3.2
6.5
26
86
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.6
6.5
14
19
E000003, ,
ATC
3.6
6.4
21
61
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
8.4
6.4
13
16
R02
ICPC
Shortness of breath/dyspnoea
2.3
6.4
53
256
WX002
NOMESCO Finland
Sedation and analgesia
2.1
6.3
73
401
1XC02, ,
NOMESCO Finland
18.4
6.3
9
5
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
18.4
6.3
9
5
D72.1
ICD-10 Finland
Eosinophilia
18.4
6.3
9
5
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
6.3
6
*
2AA01, ,
NOMESCO Finland
+∞
6.3
6
*
J17.2
ICD-10 Finland
Pneumonia in mycoses
+∞
6.3
6
*
H60.3
ICD-10 Finland
Other infective otitis externa
4.1
6.2
17
43
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
6.1
23
73
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
3.7
6.1
19
53
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.0
6.1
27
95
J01DA01
ATC
[U] cefalexin
1.8
6.1
202
1547
ZXE00
NOMESCO Finland
One hour or less
1.8
6.1
128
858
H66.9
ICD-10 Finland
Otitis media, unspecified
3.1
6.0
26
90
A03
ICPC
Fever
2.1
6.0
61
319

TimeCodeWAS

↥

TODO / Current known limitations:

  • Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
  • Legend / how to read the glyphs.
  • Proper column names.
  • Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
  • Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
  • Download CSV not working.
  • No filters and sorters.
  • Limited amount of endpoints with TimeCodeWAS data.
  • Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
Lung transplant status
Z94.2 (45609997)
voriconazole; oral, parenteral
J02AC03 (21603082)
Aspergillus sp Ab [Presence] in Serum
7808-9 (3008536)
Aspergillus fumigatus IgG Ab [Mass/volume] in Serum
26954-8 (3013803)
Legionella sp identified in Specimen by Organism specific culture
593-4 (3037692)
Pulmonary mycobacterial infection
A31.0 (45590805)
Toxoplasma gondii DNA [Presence] in Specimen by NAA with probe detection
29904-0 (3006695)
Invasive pulmonary aspergillosis
B44.0 (45547455)
Other pulmonary aspergillosis
B44.1 (45576269)
Aspergillosis, unspecified
B44.9 (45576271)
Other transplanted organ and tissue status
Z94.8 (45600381)
Other forms of aspergillosis
B44.8 (45605237)
isavuconazole; oral, parenteral
J02AC05 (1588651)
Otitis externa in aspergillosis
H62.2*B44.8 (2000502370)
Pneumonia in other aspergillosis
J17.2*B44.1 (2000502583)
Bronchial lavation
TGC00 (2001303585)
Thorax extensive CT-examination
GD1BD (2001303621)
Blood transfusion
WW500 (2001310603)
Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection
6521-9 (3009595)
Aspergillus fumigatus IgE Ab [Units/volume] in Serum
6025-1 (3011951)
Enterovirus RNA [Presence] in Specimen by NAA with probe detection
29591-5 (3016881)
Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
7993-9 (3025023)
Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection
34720-3 (3030558)
Pneumonia in invasive aspergillosis
J17.2*B44.0 (2000502582)
Paranasal sinuses X-ray examination without contrast
DM1AA (2001301740)
Flexible bronchoscopy
UGC12 (2001303610)
High resolution CT examination of lungs
GD1DD (2001303632)
Extensive high resolution CT examination of lungs
GD1ED (2001303637)
Thorax X-ray examination outside radiological department
GD1UA (2001303652)
Bone marrow biopsy
XW000 (2001310618)
ursodeoxycholic acid; oral
A05AA02 (21600513)
sulfadiazine and trimethoprim
J01EE02 (21602962)
posaconazole; oral, parenteral
J02AC04 (21603083)
Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
29257-3 (3002482)
Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
23826-1 (3012477)
Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
21363-7 (3020565)
Mycobacterium sp identified in Sputum by Organism specific culture
539-7 (3027544)
Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
34645-2 (3031478)
Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
40976-3 (3040853)
Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
38917-1 (3042194)
Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
41001-9 (3042596)
Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
43730-1 (3043849)
Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
62424-7 (40765161)
Body height measure
50373000 (4177340)
Body mass index
60621009 (4245997)
Parainfluenza type 1 nucleic acid detection
222341000000100 (44790047)
Parainfluenza type 2 nucleic acid detection
222351000000102 (44790048)
Parainfluenza type 3 nucleic acid detection
222361000000104 (44790049)
Parainfluenza type 4 nucleic acid detection
810871000000102 (44806118)
Bronchiectasis
J47 (45605889)
Panorama tomography of teeth and jaws or similar X-ray examination
EB1HA (2001301913)
Thorax X-ray examination
GD1AA (2001303617)
Thorax CT examination
GD1AD (2001303618)
Biopsy of the lung with CT guidance
GD1CT (2001303738)
Insertion of central venous catheter through external or internal jugular vein
TPH15 (2001309600)
Physiotherapy
R4110 (2001310233)
Extensive body CT
JN4BD (2001310899)
Urgent procedure
ZXD05 (2001311386)
Intravenous
ZX120 (2001311495)
Medical doctor
Z2221 (2001311556)
SMOKING - SMOKE2: no - SMOKE3: never - SMOKE5: Unspecified
SMOKING-2-3-0 (2002330113)
prednisolone
A07EA01 (21600653)
prednisolone; oral, parenteral
H02AB06 (21602734)
sulfamethoxazole and trimethoprim
J01EE01 (21602961)
levofloxacin; inhalant, oral, parenteral
J01MA12 (21603019)
moxifloxacin; oral, parenteral
J01MA14 (21603021)
itraconazole; oral, parenteral
J02AC02 (21603081)
Emergency Room and Inpatient Visit
ERIP (262)
Fungus identified in Specimen by Culture
580-1 (3000494)
Epithelial cells [#/volume] in Urine
30383-4 (3000850)
Erythrocytes [#/volume] in Urine
30391-7 (3002582)
Mycobacterium sp identified in Specimen by Organism specific culture
543-9 (3005702)
FEV1/FVC
19926-5 (3011505)
Magnesium [Moles/volume] in Serum or Plasma
2601-3 (3012095)
Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
13956-8 (3014162)
Chloride [Moles/volume] in Serum or Plasma
2075-0 (3014576)
Amylase [Enzymatic activity/volume] in Serum or Plasma
1798-8 (3016771)
Leukocytes [#/volume] in Urine
30405-5 (3018095)
Forced vital capacity [Volume] Respiratory system
19870-5 (3020158)
Urea [Moles/volume] in Serum or Plasma
22664-7 (3020779)
Bacteria identified in Blood by Culture
600-7 (3023368)
Albumin [Mass/volume] in Serum or Plasma
1751-7 (3024561)
FEV1
20150-9 (3024653)
Urinalysis microscopic panel [#/volume] - Urine by Automated count
50554-5 (3029287)
Casts [#/volume] in Urine by Automated count
51483-6 (3030467)
Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40982-1 (3038288)
Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
40987-0 (3043924)
Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
34487-9 (3044938)
Myeloperoxidase IgG Ab [Units/volume] in Serum
48404-8 (3049804)
Bacteria [Presence] in Urine
87829-8 (36304419)
Infectious Disease
44 (38004484)
Hematology
82 (38004501)
Emergency Medicine
93 (38004510)
Short blood count panel - Blood
55429-5 (40758558)
CBC W Ordered Manual Differential panel - Blood
57782-5 (40760892)
Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
66885-5 (40769539)
Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
72493-0 (43055120)
Abnormal findings on diagnostic imaging of lung
R91 (45548995)
Bacterial pneumonia, unspecified
J15.9 (45557621)
Predominantly allergic asthma
J45.0 (45557624)
Nonallergic asthma
J45.1 (45557625)
Asthma, unspecified
J45.9 (45562456)
Other otitis externa
H60.8 (45567109)
Haemoptysis
R04.2 (45577777)
Chronic maxillary sinusitis
J32.0 (45586667)
Other specified chronic obstructive pulmonary disease
J44.8 (45586673)
Chronic lymphocytic leukaemia of B-cell type
C91.1 (45600564)
Pneumonia, unspecified
J18.9 (45601123)
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
D38.1 (45605357)
Thoracic and Cardiac Surgery
OMOP4822009 (45756830)
Emergency Room Visit
ER (9203)
Pulmonary Disease
29 (38004472)
Outpatient Visit
OP (9202)
Differential panel, method unspecified - Blood
69738-3 (42870588)
salmeterol and fluticasone
R03AK06 (21603280)
Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
6768-6 (3035995)
tiotropium bromide; inhalant
R03BB04 (21603296)
C reactive protein [Mass/volume] in Serum or Plasma
1988-5 (3020460)
Eosinophils/Leukocytes in Blood
26450-7 (3006504)
Monocytes/Leukocytes in Blood
26485-3 (3019069)
Basophils [#/volume] in Blood
26444-0 (3006315)
Monocytes [#/volume] in Blood
26484-6 (3001604)
Basophils/Leukocytes in Blood
30180-4 (3022096)
Eosinophils [#/volume] in Blood
26449-9 (3013115)
Metamyelocytes/Leukocytes in Blood
28541-1 (3002179)
Lymphocytes [#/volume] in Blood
26474-7 (3019198)
Lymphocytes/Leukocytes in Blood
26478-8 (3002030)
aPTT in Platelet poor plasma by Coagulation assay
14979-9 (3018677)
Myelocytes/Leukocytes in Blood
26498-6 (3017181)
Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
14804-9 (3022250)
Promyelocytes/Leukocytes in Blood
26524-9 (3021440)
Supplier / Service Provider
OMOP5117446 (33004)
Neutrophils/Leukocytes in Blood
26511-6 (3018010)
Blood type and Crossmatch panel - Blood
34531-4 (3044640)
Normoblasts [#/volume] in Blood
715-3 (3021589)
formoterol and beclometasone
R03AK08 (43534839)
montelukast; oral
R03DC03 (21603356)
Prothrombin time (PT) actual/Normal
5894-1 (3033658)
Blasts/Leukocytes in Blood
26446-5 (3025159)
Reticulocytes/Erythrocytes in Blood
4679-7 (3027945)
Bilirubin.total [Moles/volume] in Serum or Plasma
14631-6 (3006140)
Outpatient Hospital
22 (8756)
Otolaryngology
4 (38004449)
Neutrophils [#/volume] in Blood by Automated count
751-8 (3013650)
Office Visit
OMOP4822458 (581477)
IgE [Units/volume] in Serum or Plasma
19113-0 (3005322)
Phosphate [Moles/volume] in Serum or Plasma
14879-1 (3003458)
amoxicillin and beta-lactamase inhibitor; oral, parenteral
J01CR02 (21602863)
Epithelial cells.squamous [#/volume] in Urine by Automated count
51486-9 (3029879)
Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)
Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)
salbutamol; inhalant
R03AC02 (21603256)
Inpatient Hospital
21 (8717)
doxycycline; oral, parenteral
J01AA02 (21602800)
IgM [Mass/volume] in Serum or Plasma
2472-9 (3028026)
Forced vital capacity [Volume] Respiratory system --post bronchodilation
19875-4 (3001668)
FEV1 --post bronchodilation
20155-8 (3023550)
FEV1/FVC --post bronchodilation
69970-2 (42868459)
FVC percent change Respiratory system
69982-7 (42868471)
FEV1 percent change
69983-5 (42868472)
IgG [Mass/volume] in Serum or Plasma
2465-3 (3005719)
Inpatient Visit
IP (9201)
methylprednisolone; oral, parenteral
H02AB04 (21602732)
Blood group antibody screen [Presence] in Serum or Plasma
890-4 (3001079)
Tissue Pathology biopsy report
66121-5 (40768804)
Epithelial cells.non-squamous [#/volume] in Urine by Automated count
51485-1 (3030306)
Calcium.ionized [Moles/volume] in Serum or Plasma
1995-0 (3021347)
Rhinopharyngoscopy
UDH02 (2001301680)
Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1920-8 (3013721)
filgrastim; parenteral
L03AA02 (21603851)
Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19072-8 (3016431)
Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)
Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method
4537-7 (3013707)
enoxaparin; parenteral
B01AB05 (21600976)
Internal Medicine
11 (38004456)
Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1742-6 (3006923)
Spirometry
127783003 (4133840)
Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)
Platelets [#/volume] in Blood
26515-7 (3007461)
MCH [Entitic mass]
28539-5 (3035941)
MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)
Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)
Erythrocytes [#/volume] in Blood
26453-1 (3026361)
Leukocytes [#/volume] in Blood
26464-8 (3010813)
Hemoglobin [Mass/volume] in Blood
718-7 (3000963)
pH of Serum or Plasma
2753-2 (3018418)
Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)
MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)
ABO and Rh group [Type] in Blood by Confirmatory method
77397-8 (46236098)
CBC panel - Blood by Automated count
58410-2 (40761511)
Spirometry for bronchospasm with prolonged evaluation after bronchodilator
113016006 (4010399)
calcium (different salts in combination); oral
A12AA20 (21600872)
Pharmacy visit
OMOP4822462 (581458)
Glucose [Moles/volume] in Serum or Plasma
14749-6 (3013826)
Calcium [Moles/volume] in Serum or Plasma
2000-8 (3015377)
Extensive CT examination of arteria pulmonalis
FB1BD (2001302407)
ondansetron; oral, parenteral, rectal
A04AA01 (21600493)
Urate [Moles/volume] in Serum or Plasma
14933-6 (3026493)
Nuclear Ab [Titer] in Serum
29953-7 (3037522)
Bacteria identified in Isolate by Culture
43409-2 (3042936)
fluticasone; inhalant
R03BA05 (21603288)
Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
30248-9 (3015399)
Bacterial infection, unspecified
A49.9 (45590816)
Measurement of bone density from two or more locations with X-ray
NK6QA (2001308500)
tramadol; oral, parenteral, rectal
N02AX02 (21604298)
HIV 1 and 2 tests - Meaningful Use set
75622-1 (46235355)
Gastroenterology
10 (38004455)
fluconazole; oral, parenteral
J02AC01 (21603080)
Clinical & Laboratory Dermatological Immunology Physician
207NI0002X (38003841)
fluticasone furoate
R03BA09 (45893496)
Laboratory Visit
OMOP4822461 (32036)
Bacteria [#/volume] in Urine by Automated count
51480-2 (3031040)
Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
2157-6 (3007220)
roxithromycin; oral
J01FA06 (21602974)
ciprofloxacin; oral, parenteral
J01MA02 (21603009)
More than one and less than three hours
ZXE10 (2001311401)
SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
94500-6 (706163)
INR in Blood by Coagulation assay
34714-6 (3032080)
amoxicillin; oral, parenteral
J01CA04 (21602823)
Ferritin [Mass/volume] in Serum or Plasma
2276-4 (3001122)
Cathetrisation of vein
TPH04 (2001309597)
Bacteria identified in Skin by Aerobe culture
620-5 (3007853)
EKG study
11524-6 (3013512)
Esophagoscopy, gastroscopy and duodenoscopy
UJD10 (2001304788)
Bacteria identified in Sputum by Culture
6460-0 (3023419)
Medical Oncology
90 (38004507)
Fever, unspecified
R50.9 (45582716)
valaciclovir; oral
J05AB11 (21603137)
erdosteine; oral
R05CB15 (21603394)
fluocinolone acetonide and antiinfectives
S02CA05 (21605177)
12 lead EKG panel
34534-8 (3044889)
Urinalysis macro (dipstick) panel - Urine
24357-6 (3037467)
fluticasone; nasal
R01AD08 (21605050)
fluticasone furoate; nasal
R01AD12 (21605053)
Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
2324-2 (3026910)
Bacteria identified in Urine by Culture
630-4 (3026008)
IgA [Mass/volume] in Serum or Plasma
2458-8 (3007164)
Epstein Barr virus Ab [Presence] in Serum
49178-7 (3048929)
budesonide; inhalant
R03BA02 (21603285)
cefalexin; oral
J01DB01 (21602870)
prednisone
A07EA03 (21600655)
prednisone; oral
H02AB07 (21602735)
Acute bronchitis, unspecified
J20.9 (45562445)
Spirometry study
18759-1 (3000492)
azithromycin; oral, parenteral
J01FA10 (21602978)
Other specified special examinations
Z01.8 (45581003)
clindamycin; oral, parenteral
J01FF01 (21602985)
Nitrite [Presence] in Urine by Test strip
5802-4 (3021601)
Glucose [Presence] in Urine by Test strip
25428-4 (3009261)
Case Management Agency
251B00000X (38004193)
Ketones [Presence] in Urine by Test strip
2514-8 (3035350)
One hour or less
ZXE00 (2001311394)
pantoprazole; oral, parenteral
A02BC02 (21600097)
mometasone; nasal
R01AD09 (21605051)
Standard cardiac ultrasound examination
FM1AE (2001303278)
telithromycin; oral
J01FA15 (21602983)

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
109
21
77.36
197.58
3.8
1.3
8.77
0.09
u/ml
5.73
93
13
106
53
29.11
144.82
6.2
2.4
—
—
—
0
0
203
370
12.83
124.87
5.7
1.4
—
—
—
0
0
114
9
193.13
114.82
3.0
1.7
—
—
—
0
0
127
178
11.03
93.24
4.9
1.3
1233.23
296.55
u/ml
2.19
121
165
124
248
7.44
64.69
5.4
2.3
9.53
10.94
g/l
2.47
113
228
55
50
13.02
53.38
6.0
2.8
—
—
—
0
0
151
442
5.49
50.78
3.6
2.0
—
—
—
0
0
154
506
4.86
43.87
13.1
3.4
0.80
0.83
mmol/l
2.25
149
483
40
30
15.05
43.28
1.4
1.3
2.69
2.71
g/l
0.02
23
25
40
30
15.05
43.28
1.4
1.3
0.39
0.41
g/l
0.06
24
25
123
351
5.01
41.49
2.9
1.6
—
—
—
0
0
219
974
4.78
41.14
23.8
6.5
—
—
—
0
0
39
32
13.70
39.99
1.4
1.3
—
—
—
0
0
46
52
10.13
38.12
1.5
1.9
0.80
1.03
g/l
0.33
30
44
85
199
5.42
35.79
2.8
1.6
1.20
1.34
g/l
0.20
78
180
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
192
896
3.77
30.85
11.0
4.6
—
—
—
0
0
68
153
5.35
29.63
1.8
2.2
1.79
1.46
g/l
1.44
56
137
123
438
3.90
29.53
1.8
1.8
—
—
—
0
0
257
1491
4.38
29.01
23.0
6.4
0.67
0.60
e9/l
4.74
241
1277
257
1496
4.35
28.74
22.9
6.4
0.05
0.04
e9/l
1.56
242
1282
32
32
10.98
28.72
1.4
1.3
—
—
—
0
0
257
1518
4.24
27.59
23.2
6.4
1.72
1.87
e9/l
1.25
244
1341
32
34
10.32
27.51
3.0
2.5
10.76
23.72
iu/ml
—
10
5
258
1544
4.18
26.78
25.5
6.6
0.23
0.20
e9/l
1.27
245
1351
57
121
5.49
26.38
1.6
1.4
—
—
—
0
0
108
401
3.53
23.65
14.2
6.3
1.05
1.04
mmol/l
0.21
102
380
260
1663
3.75
22.15
33.4
10.6
4.59
4.16
e9/l
2.05
249
1460
42
82
5.73
21.14
1.5
1.3
—
—
—
0
0
224
1348
3.10
20.36
14.0
6.5
1.21
1.21
mmol/l
0.42
218
1245
25
7
38.48
20.14
7.5
1.4
—
—
—
0
0
82
280
3.57
20.13
11.1
4.4
0.91
0.87
%
0.06
54
106
79
266
3.60
19.79
10.8
4.4
0.79
0.56
%
0.60
53
96
35
61
6.31
19.75
2.1
1.4
—
—
—
0
0
216
1292
2.98
19.51
11.4
5.3
32.71
35.44
g/l
7.86
211
1219
33
56
6.44
19.10
2.1
1.4
137.58
159.38
au/ml
0.39
12
13
29
43
7.30
19.01
11.3
3.7
—
—
—
0
0
235
1488
3.06
18.81
18.2
7.5
1.21
1.21
mmol/l
0.29
214
1291
91
365
3.07
16.91
9.8
7.3
1.57
0.71
mmol/l
1.15
78
305
91
367
3.05
16.73
9.8
7.3
7.42
7.41
ph
0.48
56
216
73
260
3.33
16.54
11.7
4.5
0.11
0.15
%
0.23
47
85
94
399
2.90
15.66
1.6
1.3
473.04
415.60
titre
0.15
23
100
162
906
2.56
15.53
9.1
4.6
7.40
7.40
ph
0.10
123
642
143
767
2.54
14.82
2.9
2.2
3.16
3.06
mg/l
0.17
128
663
42
111
4.19
14.66
5.1
2.0
22.52
21.45
s
0.15
42
105
20
9
23.56
14.40
1.1
1.0
—
—
—
0
0
70
271
3.01
13.60
12.6
4.9
0.14
0.19
%
0.16
44
84
19
9
22.31
13.49
1.3
1.2
—
—
—
0
0
68
262
3.01
13.31
11.9
8.6
—
—
—
0
0
20
12
17.65
13.15
1.7
1.2
—
—
—
0
0
55
189
3.30
13.04
4.2
4.1
—
—
—
0
0
115
589
2.47
12.81
2.3
1.4
2.24
2.53
g/l
1.01
92
360
33
81
4.42
12.63
1.7
2.4
119.11
126.66
g/l
0.62
18
62
60
225
3.04
12.26
8.0
3.7
7.43
7.42
ph
0.88
53
185
16
6
27.92
12.16
3.8
1.8
34.38
29.17
%
—
16
6
17
9
19.84
11.71
3.8
3.2
—
—
—
0
0
28
64
4.69
11.69
1.6
1.1
294.43
301.61
u/ml
0.03
14
31
23
26
9.43
11.46
1.2
1.2
—
—
—
0
0
96
476
2.44
11.28
6.1
3.3
1.06
1.69
e6/l
0.76
62
246
16
8
20.94
11.24
2.5
1.1
—
—
—
0
0
141
827
2.24
11.18
6.2
3.4
0.40
0.44
e6/l
0.06
119
608
50
178
3.14
11.13
5.1
3.9
24.74
24.22
mmol/l
0.42
50
178
144
857
2.22
10.96
22.1
6.5
—
—
—
0
0
212
1475
2.24
10.85
16.7
14.1
1.21
1.26
inr
0.83
185
1227
120
667
2.26
10.76
3.2
1.7
2.33
1.53
mg/l
0.49
107
536
70
305
2.65
10.74
6.5
3.8
2.54
1.79
mmol/l
0.69
62
257
193
1298
2.19
10.70
32.3
12.1
0.00
0.00
e9/l
0.08
165
1064
55
212
2.92
10.64
1.6
1.5
—
—
—
0
0
238
1761
2.29
10.12
11.9
4.9
6.55
6.74
mmol/l
0.83
230
1681
56
224
2.81
10.11
2.4
2.5
—
—
—
0
0
67
295
2.60
10.03
2.6
1.5
—
—
—
0
0
70
315
2.56
10.02
5.4
2.9
60.98
69.96
e9/l
1.32
51
234
21
26
8.55
9.99
1.6
1.2
—
—
—
0
0
132
781
2.16
9.99
5.9
3.3
—
0.00
estimate
—
0
6
14
7
20.81
9.88
5.4
3.3
—
—
—
0
0
99
524
2.28
9.86
4.1
2.7
10.31
13.08
umol/l
3.66
93
488
21
44
5.03
9.68
1.8
1.3
—
—
—
0
0
94
492
2.28
9.58
3.8
2.7
2.14
2.27
g/l
1.43
88
454
276
2202
2.62
9.51
30.7
9.1
86.70
80.69
u/l
1.30
271
2092
19
37
5.39
9.48
1.6
1.2
—
—
—
0
0
158
1018
2.07
9.40
7.0
3.6
2.31
2.35
mmol/l
2.73
150
914
69
318
2.48
9.35
6.6
3.8
7.37
7.38
ph
1.63
49
187
90
467
2.28
9.33
3.9
2.6
17.83
23.18
%
3.48
84
438
26
68
4.07
9.15
3.0
2.6
57.00
60.32
%
0.50
26
68
28
78
3.83
9.05
8.1
3.4
2.65
2.19
index
0.16
20
48
60
264
2.56
8.94
1.9
1.4
—
—
—
0
0
77
381
2.34
8.88
5.1
2.9
5.03
4.97
e9/l
0.03
63
332
20
29
7.27
8.69
1.7
2.8
45.50
40.60
%
—
8
15
241
1849
2.15
8.54
7.4
4.7
12.13
145.10
e6/l
—
8
41
178
1233
1.97
8.30
3.6
2.5
78.40
76.89
nmol/l
0.26
164
1098
151
992
1.97
8.19
6.6
3.4
54.05
121.77
e6/l
0.44
128
779
20
47
4.47
8.06
3.4
2.6
5.47
4.65
e9/l
0.48
20
47
31
103
3.22
7.69
1.9
3.7
1.79
2.61
ratio
0.42
18
63
147
972
1.93
7.69
8.9
2.6
—
—
—
0
0
64
312
2.31
7.56
11.3
7.8
117.97
121.53
g/l
0.77
64
306
66
327
2.28
7.51
2.0
1.6
—
—
—
0
0
40
158
2.75
7.34
10.2
3.9
—
—
—
0
0
43
177
2.65
7.29
14.1
8.4
15.56
15.85
%
0.30
43
170
161
1112
1.88
7.25
7.8
4.1
15.39
84.80
e6/l
3.52
132
810
100
593
1.99
7.10
4.2
2.9
552.99
547.66
mosm/kgh2o
0.09
94
522
32
114
3.00
7.07
1.9
4.2
53.56
57.05
mg/l
0.09
27
100
32
114
3.00
7.07
1.9
4.2
40.35
51.83
mg/l
0.28
26
101
11
8
14.17
6.94
1.9
1.6
—
—
—
0
0
25
78
3.39
6.85
1.6
1.6
—
—
—
0
0
13
14
9.62
6.85
2.8
1.3
41.85
60.75
ug/l
0.70
13
14
178
1286
1.84
6.80
4.8
3.0
375.24
146.35
ug/l
1.12
172
1192
10
6
17.14
6.78
1.1
1.0
—
—
—
0
0
11
9
12.59
6.63
1.1
1.0
—
—
—
0
0
18
46
4.08
6.53
1.4
1.2
1.91
3.79
u/ml
0.77
11
19
122
792
1.86
6.51
8.2
3.1
337.39
357.02
umol/l
1.30
112
701
184
1355
1.82
6.49
7.4
2.9
—
—
estimate
—
0
0
155
1084
1.82
6.49
2.7
2.2
—
—
—
0
0
56
276
2.24
6.41
3.1
2.7
32.65
37.04
u/l
0.37
49
231
18
36
5.23
6.28
1.2
1.3
—
—
—
0
0
41
179
2.48
6.16
1.7
1.7
—
—
—
0
0
70
384
2.05
6.08
2.0
1.6
—
—
—
0
0
12
15
8.26
5.89
2.0
2.2
2162.83
1077.07
u/ml
0.42
12
15
22
70
3.30
5.86
1.9
5.0
—
—
—
0
0
238
1943
1.83
5.49
7.4
4.5
—
2.43
—
0
6
83
503
1.87
5.35
1.7
1.7
989.50
1250.11
nmol/l
2.15
65
378
21
69
3.18
5.32
1.6
1.2
—
—
—
0
0
21
69
3.18
5.32
4.3
2.9
—
—
—
0
0
15
30
5.19
5.32
1.4
1.5
—
—
—
0
0
103
669
1.79
5.30
14.3
5.1
—
—
—
0
0
163
1219
1.67
4.96
5.2
4.0
29.83
38.91
ng/l
0.68
125
923
41
198
2.22
4.91
8.0
6.2
24.93
24.19
mmol/l
0.65
41
188
14
30
4.83
4.74
1.4
1.0
—
—
—
0
0
173
1326
1.65
4.69
2.7
2.1
96.11
96.11
pmol/l
0.00
117
697
16
48
3.45
4.67
2.3
1.5
—
—
—
0
0
120
843
1.67
4.55
3.5
3.1
—
—
—
0
0
14
32
4.52
4.49
1.0
1.2
—
—
—
0
0
93
612
1.73
4.48
4.9
3.9
432.36
391.50
ng/l
0.08
80
498
14
33
4.38
4.37
1.4
1.6
—
—
—
0
0
22
84
2.74
4.33
1.2
1.2
—
83.75
—
0
8
129
936
1.62
4.24
2.2
1.7
17.34
20.18
nmol/l
1.97
122
782
11
21
5.38
4.18
12.0
2.6
0.36
0.86
index
1.70
11
21
20
74
2.81
4.17
1.3
1.6
287.29
280.11
ug/g
0.05
14
48
8
10
8.17
4.08
11.6
4.5
45.13
50.10
%
—
8
10
22
87
2.64
4.06
7.7
6.0
1.17
1.32
mmol/l
0.37
22
78
244
2725
0.59
3.98
5.3
5.3
1.41
1.42
mmol/l
0.17
230
2511
98
674
1.65
3.94
4.6
3.8
—
0.25
—
0
8
48
268
1.93
3.92
2.4
2.4
14.32
9.07
ug/l
0.71
42
238
7
8
8.91
3.79
1.4
1.5
—
—
—
0
0
29
136
2.24
3.74
1.8
1.3
—
—
—
0
0
53
312
1.83
3.68
2.0
2.5
288.95
113.13
ug/g
0.95
41
246
252
2780
0.59
3.65
5.9
6.1
2.57
2.63
mmol/l
0.51
234
2568
25
112
2.33
3.58
1.9
2.3
3.05
5.31
iu/ml
—
6
33
13
37
3.62
3.44
2.1
2.2
—
—
—
0
0
11
27
4.18
3.42
1.6
3.6
1110.36
937.48
mg
0.13
11
27
155
1218
1.52
3.40
4.4
3.6
6.23
6.19
ph
0.17
87
706
248
2732
0.62
3.25
5.3
5.4
4.48
4.51
mmol/l
0.19
233
2529
185
1520
1.50
3.21
5.1
3.8
0.00
0.00
estimate
-0.00
36
306
123
929
1.52
3.21
4.3
2.2
156.12
296.12
u/l
0.86
116
883
12
35
3.52
3.14
1.7
1.9
—
—
—
0
0
33
176
1.97
3.09
2.2
2.6
—
12.95
—
0
17
9
21
4.38
3.01
2.3
1.3
—
—
—
0
0
185
1534
1.47
2.98
5.2
3.9
0.00
0.00
estimate
-0.00
36
314
43
255
1.79
2.93
3.1
2.2
0.00
0.00
estimate
—
6
54
231
2009
1.51
2.88
7.5
4.4
—
0.14
—
0
7
6
9
6.76
2.88
1.2
1.0
1036.00
1424.00
miu/ml
—
6
9
6
9
6.76
2.88
1.2
1.0
—
—
—
0
0
28
146
2.00
2.80
7.8
4.5
1.70
1.57
%
0.37
28
136
185
1548
1.45
2.76
5.3
3.9
0.00
0.01
estimate
0.50
34
295
7
14
5.08
2.74
1.0
1.1
—
—
—
0
0
26
133
2.04
2.74
8.0
4.7
0.93
0.86
%
0.56
26
123
27
141
2.00
2.69
2.7
2.4
—
—
—
0
0
81
1082
0.67
2.57
3.5
3.3
—
—
—
0
0
59
398
1.59
2.50
1.6
1.3
—
—
—
0
0
12
45
2.73
2.48
1.3
1.1
—
—
—
0
0
11
38
2.96
2.44
2.1
1.0
—
—
—
0
0
11
38
2.96
2.44
2.1
1.0
—
—
—
0
0
126
1002
1.42
2.39
5.0
3.3
1402.78
1315.32
ng/l
0.11
120
852
11
39
2.88
2.36
2.4
2.4
-0.64
0.80
mmol/l
0.83
11
39
214
1869
1.42
2.34
7.4
3.6
68.28
52.54
u/l
1.20
207
1757
51
338
1.60
2.33
4.1
4.6
3.92
49.22
ug/l
1.19
42
284
6
13
4.68
2.28
1.2
1.0
—
—
—
0
0
5
10
5.06
2.08
2.0
3.6
0.61
0.59
mmol/l
—
5
10
244
2644
0.70
2.07
6.5
6.8
40.31
39.62
mmol/mol
0.54
231
2479
11
45
2.49
1.95
4.5
2.4
30.64
32.93
pg
0.94
11
45
5
11
4.60
1.95
1.2
1.2
30.60
27.55
s
—
5
11
14
65
2.21
1.91
7.2
5.6
104.36
105.39
mmol/l
0.54
14
59
14
65
2.21
1.91
7.2
5.6
11.64
11.47
mmol/l
0.07
14
59
43
288
1.57
1.89
3.9
2.6
0.17
0.21
e6/l
0.16
43
278
9
34
2.69
1.88
1.7
1.2
—
—
—
0
0
8
28
2.90
1.87
1.6
1.9
7.74
10.84
%
—
8
28
99
785
1.37
1.84
1.8
1.4
—
—
—
0
0
8
30
2.71
1.73
2.6
1.6
—
—
—
0
0
5
13
3.89
1.72
1.4
1.1
—
—
—
0
0
10
42
2.42
1.63
1.1
1.1
—
12.54
—
0
12
14
70
2.04
1.61
1.4
1.2
—
—
—
0
0
243
2605
0.74
1.56
4.8
4.5
1.31
1.28
mmol/l
0.27
231
2390
8
33
2.46
1.54
1.9
3.1
—
—
—
0
0
289
2735
1.49
1.51
65.4
17.3
30.79
24.98
mg/l
2.47
274
2277
46
330
1.46
1.50
2.2
2.5
14.48
13.35
nmol/l
0.30
40
298
66
506
1.38
1.49
1.4
1.3
26.77
34.99
iu/ml
0.29
17
170
5
16
3.16
1.44
1.0
1.1
132.00
132.38
nmol/l
—
5
16
6
22
2.76
1.44
1.0
1.4
—
—
—
0
0
79
627
1.34
1.44
1.7
1.8
474.72
442.88
pmol/l
0.34
71
527
27
175
1.59
1.39
5.2
2.6
0.77
0.64
%
0.38
27
175
7
146
0.47
1.35
1.0
1.1
—
—
—
0
0
6
24
2.53
1.31
1.2
1.0
—
—
—
0
0
8
34
2.39
1.30
1.0
1.3
—
—
—
0
0
226
2077
1.29
1.29
4.2
4.0
14.93
14.89
pmol/l
0.08
214
1878
45
340
1.38
1.13
1.3
1.4
—
—
—
0
0
50
386
1.35
1.10
1.3
1.3
—
—
—
0
0
15
89
1.72
1.09
1.2
1.3
33.79
26.46
iu/l
—
9
77
5
21
2.40
1.09
4.8
2.3
—
—
—
0
0
10
53
1.91
1.02
1.3
1.4
—
—
—
0
0
80
668
1.26
1.00
4.6
4.1
1.02
1.02
kg/l
0.84
62
445
20
137
1.49
0.86
2.6
2.7
—
—
—
0
0
8
46
1.76
0.83
3.0
2.1
10.77
10.65
mmol/l
—
8
46
0
26
0.00
0.78
0.0
1.0
—
260.24
—
0
17
257
2674
0.82
0.74
5.8
5.4
5.91
6.03
mmol/l
0.70
246
2453
10
60
1.69
0.73
2.1
1.8
2.52
2.88
iu/l
—
5
25
5
28
1.80
0.66
2.4
4.0
7.70
8.67
mmol/l
—
5
28
29
226
1.31
0.64
4.2
3.6
—
—
—
0
0
109
1203
0.86
0.62
2.2
2.0
1.28
1.35
mmol/l
0.61
91
997
0
20
0.00
0.60
0.0
1.7
—
1.42
—
0
14
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
55
468
1.21
0.60
1.3
1.3
3.17
13.15
u/ml
1.78
20
187
0
23
0.00
0.58
0.0
1.9
—
—
—
0
0
95
851
1.16
0.58
5.3
4.0
0.00
0.01
estimate
0.50
34
287
5
88
0.56
0.57
1.0
1.2
—
—
—
0
0
6
37
1.63
0.56
1.7
1.9
88.13
90.22
%
—
6
37
6
39
1.55
0.53
1.0
1.3
—
—
—
0
0
7
46
1.53
0.48
2.4
7.1
6.47
7.28
mmol/l
—
7
37
127
1181
1.12
0.44
4.5
3.7
0.00
0.02
estimate
0.69
30
266
9
131
0.68
0.44
1.6
1.8
42.67
39.66
nmol/l
—
9
124
8
58
1.39
0.42
1.1
2.8
6.68
9.49
pmol/l
—
8
58
0
15
0.00
0.41
0.0
15.0
—
902.73
—
0
15
26
214
1.23
0.41
1.2
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
3.7
—
34.53
—
0
12
14
107
1.32
0.38
2.4
3.6
221.00
246.39
mg/l
—
8
41
5
37
1.36
0.37
8.8
3.4
5.80
3.24
nmol/l
—
5
37
70
636
1.13
0.36
1.3
1.2
0.88
1.38
u/ml
0.63
22
176
113
1061
1.10
0.32
4.6
3.4
7.05
8.07
mmol/l
1.75
104
882
111
1042
1.10
0.32
5.2
4.2
17.37
7.66
mg/mmol
1.20
79
667
5
72
0.69
0.26
1.8
1.5
—
—
—
0
0
9
77
1.17
0.24
1.2
1.4
—
270.91
—
0
35
6
82
0.73
0.24
2.0
1.5
—
—
—
0
0
15
124
1.22
0.24
3.8
1.9
—
—
—
0
0
108
1026
1.08
0.24
4.4
3.5
79.96
50.35
mg/l
0.66
77
690
7
93
0.75
0.22
1.3
1.1
1.84
1.54
g/l
—
7
93
5
42
1.19
0.21
4.8
3.2
110.20
105.21
mmol/l
—
5
42
5
42
1.19
0.21
4.8
3.2
4.06
4.03
mmol/l
—
5
42
5
42
1.19
0.21
4.8
3.2
1.23
1.18
mmol/l
—
5
42
0
14
0.00
0.20
0.0
10.9
—
0.66
—
0
14
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
20
175
1.15
0.19
1.1
1.3
—
—
—
0
0
91
869
1.07
0.17
4.3
3.2
0.00
0.00
estimate
0.50
31
247
6
78
0.76
0.15
1.0
1.6
—
—
—
0
0
6
79
0.76
0.15
2.0
1.5
—
—
—
0
0
6
80
0.75
0.15
2.2
1.5
—
—
—
0
0
6
80
0.75
0.15
2.0
1.5
—
—
—
0
0
8
96
0.83
0.14
1.5
1.2
0.83
0.90
g/l
—
8
96
254
2511
1.05
0.11
5.3
5.0
1.86
1.99
mu/l
1.13
238
2296
284
2816
1.06
0.11
41.1
15.4
—
—
—
0
0
9
87
1.04
0.07
1.1
1.1
—
—
—
0
0
10
89
1.13
0.07
1.2
1.2
14.24
8.08
u/l
—
5
69
8
91
0.88
0.07
13.3
13.5
—
—
—
0
0
14
129
1.09
0.05
1.1
1.3
—
—
—
0
0
14
134
1.05
0.00
1.0
1.5
0.18
0.35
mg/l
—
7
56
80
806
0.99
0.00
3.3
3.3
0.61
0.80
ug/l
2.07
58
533
22
218
1.01
0.00
1.2
1.4
—
—
—
0
0
10
95
1.05
0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
17.30
—
0
6
0
6
0.00
0.00
0.0
1.7
—
59.00
—
0
6
0
6
0.00
0.00
0.0
1.2
—
1.19
—
0
6
0
5
0.00
-0.00
0.0
6.4
—
6.33
—
0
5
6
68
0.88
-0.00
8.8
4.4
30.17
29.12
mg/l
—
6
51
6
64
0.94
-0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
0.00
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
2664.43
—
0
7
8
80
1.00
-0.00
7.4
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
20.20
—
0
5
134
1340
1.00
-0.00
5.2
5.7
1.86
2.52
ug/l
1.26
119
1205
0
7
0.00
-0.00
0.0
4.6
—
24.07
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_ASPERGILLOSIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ASPERGILLOSIS 4.089 [3.03, 5.52] < 0.001
Birth year 0.994 [0.99, 1.0] 0.199

During the follow-up period (1.1.1998 — 31.12.2019), 157 out of 432 females with AB1_ASPERGILLOSIS died.

Males

Parameter HR [95% CI] p-value
AB1_ASPERGILLOSIS 5.317 [4.05, 6.99] < 0.001
Birth year 0.988 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 377 out of 732 males with AB1_ASPERGILLOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ASPERGILLOSIS.

N-year risk Females Males
1 0.413% 0.945%
5 2.448% 6.264%
10 6.095% 14.861%
15 11.683% 27.194%
20 19.595% 41.719%

Relationships between endpoints

↥

Index endpoint: AB1_ASPERGILLOSIS – Aspergillosis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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