Aspergillosis

AB1_ASPERGILLOSIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B44
  • Hospital discharge: ICD-9 1173
  • Hospital discharge: ICD-8 1173
  • Cause of death: ICD-10 B44
  • Cause of death: ICD-9 1173
  • Cause of death: ICD-8 1173

2 out of 7 registries used, show all original rules.

413

4. Check minimum number of events

None

413

5. Include endpoints

None

413

6. Filter based on genotype QC (FinnGen only)

312

Control definitions (FinnGen only)

Control exclude
AB1_MYCOSES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1897 694 1166
Only index persons 1320 508 812
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 62.18 61.22 62.71
Only index persons 62.61 60.94 63.65

-FinnGen-

Key figures

All Female Male
Number of individuals 312 120 192
Unadjusted period prevalence (%) 0.07 0.04 0.09
Median age at first event (years) 64.10 59.62 66.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
327
Matched controls
3270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
167.5
146
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
18.3
146.8
148
141
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
20.2
137.8
124
96
J02AC03
ATC
voriconazole; systemic
407.5
134.0
126
5
TGC00
NOMESCO Finland
Bronchial lavation
24.8
128.6
100
57
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
11.3
102.2
144
213
J01MA14
ATC
moxifloxacin; systemic
10.4
87.9
125
184
R03BB04
ATC
tiotropium bromide; inhalant
9.3
81.0
128
212
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
80.6
74
*
GD1AD
NOMESCO Finland
Thorax CT examination
11.3
80.2
100
123
J18.9
ICD-10 Finland
Pneumonia, unspecified
8.2
80.0
216
626
J47
ICD-10 Finland
Bronchiectasis
23.3
76.4
58
30
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.2
69.5
84
98
R04.2
ICD-10 Finland
Haemoptysis
16.8
69.2
62
45
B44.9
ICD-10 Finland
Aspergillosis, unspecified
+∞
67.0
62
*
B44.8
ICD-10 Finland
Other forms of aspergillosis
773.7
66.4
63
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
8.4
64.5
103
169
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
15.4
64.0
60
47
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
14.0
64.0
64
56
127
Kela drug reimbursment
Transplant complication
31.1
61.1
41
15
J45.0
ICD-10 Finland
Predominantly allergic asthma
7.7
52.6
88
150
J01MA12
ATC
levofloxacin; systemic
5.7
52.5
150
426
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
5.4
49.2
144
414
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.2
45.2
260
1262
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
+∞
43.7
41
*
H02AB06
ATC
prednisolone; systemic
5.4
42.5
247
1185
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
40.7
127
377
R03AK08
ATC
formoterol and beclometasone; inhalant
9.2
40.4
53
67
J45.9
ICD-10 Finland
Asthma, unspecified
4.8
40.3
128
385
J45.1
ICD-10 Finland
Nonallergic asthma
6.9
40.3
71
126
R03DC03
ATC
montelukast; oral
5.1
39.3
108
288
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.9
38.8
113
316
XG410
NOMESCO Finland
Flow-volume spirometry
8.6
36.7
51
69
L03AA02
ATC
filgrastim; parenteral
10.0
36.3
44
50
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.4
35.5
57
91
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.4
35.4
50
69
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.9
34.4
59
101
H02AB04
ATC
methylprednisolone; systemic
4.6
33.7
102
291
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.4
33.6
63
118
R81
ICPC
Pneumonia
8.6
32.2
44
58
R03AC12
ATC
salmeterol; inhalant
7.1
31.6
52
85
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.9
30.2
79
199
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.3
30.0
56
104
R50.9
ICD-10 Finland
Fever, unspecified
4.2
28.9
100
312
XW000
NOMESCO Finland
Bone marrow biopsy
7.1
28.7
47
76
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.4
28.0
35
41
J46
ICD-10 Finland
Status asthmaticus
12.1
27.9
29
26
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.8
27.7
231
1270
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
27.2
62
138
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.5
27.2
80
220
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
26.4
87
260
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6.1
26.3
50
94
H02AB07
ATC
prednisone; oral
4.2
26.2
84
246
J02AC05
ATC
isavuconazole; systemic
269.8
25.0
25
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
24.8
85
261
R03DA04
ATC
theophylline; systemic, rectal
5.6
24.1
50
102
R03AC13
ATC
formoterol; inhalant
6.1
23.6
44
81
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
8.3
23.4
32
42
R03BA01
ATC
beclometasone; inhalant
4.0
23.1
79
241
J02AC04
ATC
posaconazole; systemic
246.6
22.9
23
*
WW500
NOMESCO Finland
Blood transfusion
6.5
22.9
40
69
R03BA05
ATC
fluticasone; inhalant
3.5
22.3
98
354
J45.8
ICD-10 Finland
Mixed asthma
8.5
21.6
29
37
H02AB09
ATC
hydrocortisone; systemic
8.2
21.6
30
40
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
82.3
21.0
23
*
WW200
NOMESCO Finland
Immunization
9.3
20.9
26
30
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.3
20.3
31
46
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
6.8
20.1
33
53
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
20.1
154
761
J17.2*B44.1
ICD-10 Finland
Pneumonia in other aspergillosis
+∞
20.0
19
*
JN4BD
NOMESCO Finland
Extensive body CT
3.9
20.0
70
216
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
8.1
19.4
27
36
WX892
NOMESCO Finland
Monitored bed care
4.6
19.4
51
127
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.6
19.4
51
127
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
5.9
19.0
36
67
GDC00
NOMESCO Finland
Lobectomy of lung
74.4
18.9
21
*
J17.2*B44.0
ICD-10 Finland
Pneumonia in invasive aspergillosis
+∞
18.9
18
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.1
18.8
43
95
J01FA06
ATC
roxithromycin; oral
2.8
18.8
174
942
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.3
18.3
39
81
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
28.6
18.1
24
9
A07AA02
ATC
nystatin; oral
5.3
17.8
38
79
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.3
17.6
50
132
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.0
17.3
32
58
L04AA06
ATC
mycophenolic acid; systemic
14.3
17.3
29
22
R03AC02
ATC
salbutamol; inhalant
2.8
17.2
217
1354
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.6
17.1
34
66
L04AD02
ATC
tacrolimus; systemic
23.4
17.1
24
11
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.3
17.0
48
126
R03AK11
ATC
formoterol and fluticasone; inhalant
7.2
16.8
26
39
49300
ICD-8 Finland
Asthma, bronchiale
7.2
16.8
26
39
A04AA01
ATC
ondansetron; systemic, rectal
4.0
16.8
52
146
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.0
16.6
98
413
J01FF01
ATC
clindamycin; systemic
2.8
16.5
121
573
J45
ICD-10 Finland
Asthma
3.8
16.5
57
173
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
13.8
16.5
28
22
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
16.2
116
541
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
16.0
110
502
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.3
15.9
24
35
J01FA09
ATC
clarithromycin; systemic
2.6
15.4
129
649
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
6.7
15.2
25
40
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.3
15.0
26
44
JN4CD
NOMESCO Finland
Very extensive body CT
5.7
14.9
29
55
Z2446
NOMESCO Finland
Social worker
4.4
14.8
40
101
JN4AD
NOMESCO Finland
Body CT examination
3.2
14.6
69
255
R03AK07
ATC
formoterol and budesonide; inhalant
2.8
14.5
93
407
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.6
14.4
24
39
ZX120
NOMESCO Finland
Intravenous
3.4
14.4
57
189
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
14.3
94
417
J96.1
ICD-10 Finland
Chronic respiratory failure
7.1
14.2
22
33
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.7
14.1
98
446
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
25.1
13.9
19
8
J01FA15
ATC
telithromycin; oral
3.5
13.9
53
171
L04AD01
ATC
ciclosporin; systemic
12.9
13.8
24
20
J01FA10
ATC
azithromycin; systemic
2.5
13.8
205
1324
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
19.3
13.5
20
11
J02AC02
ATC
itraconazole; systemic
2.9
13.5
77
316
J01AA02
ATC
doxycycline; systemic
3.2
13.1
279
2115
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
6.5
13.1
22
36
R03BA08
ATC
ciclesonide; inhalant
3.6
12.9
47
147
A02BC02
ATC
pantoprazole; systemic
2.7
12.8
254
1844
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.3
12.8
35
89
XG474
NOMESCO Finland
Exhalation nntrogen oxide
6.0
12.6
23
41
J01GB01
ATC
tobramycin; inhalant, parenteral
135.0
12.5
13
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
12.4
161
965
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
12.3
124
666
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
16.7
12.3
19
12
R03BA02
ATC
budesonide; inhalant
2.6
12.1
84
379
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.9
12.1
38
107
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
12.1
85
386
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
12.1
60
227
ZXD05
NOMESCO Finland
Urgent procedure
2.4
11.8
118
630
R06.0
ICD-10 Finland
Dyspnoea
2.4
11.8
119
638
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
67.4
11.7
13
*
A05AA02
ATC
ursodeoxycholic acid; oral
10.6
11.2
21
21
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.7
11.0
21
39
Z94.2
ICD-10 Finland
Lung transplant status
44.9
11.0
13
*
M05BA04
ATC
alendronic acid; oral
3.5
11.0
41
130
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
10.9
75
336
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.3
10.9
44
147
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.5
10.8
27
64
ZX112
NOMESCO Finland
Subcutaneous
5.5
10.7
21
40
J02AC01
ATC
fluconazole; systemic
2.2
10.7
127
724
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
113.5
10.5
11
*
J05AB11
ATC
valaciclovir; oral
2.6
10.5
69
302
B44.7
ICD-10 Finland
Disseminated aspergillosis
+∞
10.5
10
*
C03CA01
ATC
furosemide; systemic
2.2
10.4
130
754
SPAT1255
SPAT
Intravenous administration of medicine
3.7
10.3
34
99
R4110
NOMESCO Finland
Physiotherapy
2.2
10.2
113
625
R03AC03
ATC
terbutaline; inhalant
2.8
10.1
58
236
ZX108
NOMESCO Finland
Inhalation
15.2
10.1
16
11
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
10.1
92
468
R4190
NOMESCO Finland
Nutritional therapy
4.6
10.0
24
55
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.4
9.9
37
117
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.7
9.9
33
97
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
9.8
72
331
L03AA13
ATC
pegfilgrastim; parenteral
4.1
9.6
27
70
B02AA02
ATC
tranexamic acid; systemic
2.8
9.5
53
213
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
9.4
9
*
R03BB01
ATC
ipratropium bromide; inhalant
4.1
9.3
26
67
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
14.2
9.3
15
11
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
5.2
9.2
19
38
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
11.9
9.2
16
14
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.3
9.1
24
59
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
9.1
23
55
Z3226
NOMESCO Finland
Physiotherapist
2.4
9.1
75
364
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
19.3
9.0
13
7
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
13.0
9.0
15
12
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.1
8.8
105
591
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
14.6
8.8
14
10
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.6
8.7
21
48
J85.2
ICD-10 Finland
Abscess of lung without pneumonia
51.4
8.7
10
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
51.4
8.7
10
*
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
5.0
8.7
19
40
UDM02
NOMESCO Finland
Sinoscopy
6.7
8.6
21
33
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
16.8
8.6
13
8
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
28.4
8.5
11
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
8.5
82
424
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
92.3
8.5
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
8.4
85
447
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
+∞
8.4
8
*
R01AD09
ATC
mometasone; nasal
2.0
8.4
155
1022
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
8.3
45
177
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.8
8.3
45
177
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.4
8.3
31
98
WX872
NOMESCO Finland
Intensive care
3.5
8.3
30
93
J01DB01
ATC
cefalexin; oral
2.5
8.3
280
2295
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
15.0
8.3
13
9
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.1
8.3
35
120
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.1
8.2
19
28
RS220, ,
NOMESCO Finland
17.7
8.1
12
7
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
34.3
8.1
10
*
N02AA05
ATC
oxycodone; systemic
2.2
8.1
81
424
J98.1
ICD-10 Finland
Pulmonary collapse
22.7
8.1
11
5
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.9
8.0
19
29
Z2221
NOMESCO Finland
Medical doctor
2.1
8.0
98
556
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.0
7.9
23
61
H60.8
ICD-10 Finland
Other otitis externa
4.2
7.9
21
52
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
7.9
52
226
R01AD08
ATC
fluticasone; nasal
2.1
7.9
102
590
A41.9
ICD-10 Finland
Sepsis, unspecified
4.1
7.8
22
57
M04AA01
ATC
allopurinol; systemic
2.4
7.8
62
294
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.3
7.8
31
102
J01CA04
ATC
amoxicillin; systemic
2.3
7.8
272
2220
5BA08, ,
NOMESCO Finland
46.1
7.7
9
*
L01BB05
ATC
fludarabine; systemic
46.1
7.7
9
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.6
7.7
26
77
R06.2
ICD-10 Finland
Wheezing
4.0
7.7
22
58
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
18.9
7.6
11
6
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
12.2
7.6
13
11
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
25.7
7.6
10
*
XX2RW, ,
NOMESCO Finland
10.4
7.6
14
14
R03DC01
ATC
zafirlukast; oral
7.4
7.6
17
24
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.5
158
1078
N03AX16
ATC
[U] pregabalin
2.1
7.4
87
483
A02BC01
ATC
omeprazole; systemic
2.0
7.4
98
570
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.3
7.4
19
46
R06AE07
ATC
cetirizine; oral
1.9
7.4
139
912
A10AC01
ATC
insulin (human); parenteral
2.9
7.4
37
140
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
20.6
7.2
10
5
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
9.1
7.1
14
16
J43.9
ICD-10 Finland
Emphysema, unspecified
6.1
7.0
18
31
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
7.8
7.0
15
20
AA1AD
NOMESCO Finland
CT of head and brain
1.9
7.0
111
686
WX600
NOMESCO Finland
Single shot through catheter
14.2
6.9
11
8
J32.4
ICD-10 Finland
Chronic pansinusitis
8.5
6.9
14
17
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
9.6
6.8
13
14
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
6.8
23
68
Z94.0
ICD-10 Finland
Kidney transplant status
17.1
6.8
10
6
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
17.1
6.8
10
6
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.7
6.7
16
25
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.6
6.6
11
9
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
7.1
6.6
15
22
J96.0
ICD-10 Finland
Acute respiratory failure
10.3
6.6
12
12
M05BA07
ATC
risedronic acid; oral
5.5
6.6
18
34
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
6.6
27
91
B03XA02
ATC
darbepoetin alfa; parenteral
6.4
6.6
16
26
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
6.4
6.6
16
26
A10AB05
ATC
insulin aspart; parenteral
2.7
6.5
36
143
H60
ICD-10 Finland
Otitis externa
3.2
6.5
26
86
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.6
6.5
14
19
E000003, ,
ATC
3.6
6.4
21
61
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
8.4
6.4
13
16
R02
ICPC
Shortness of breath/dyspnoea
2.3
6.4
53
256
WX002
NOMESCO Finland
Sedation and analgesia
2.1
6.3
73
401
D72.1
ICD-10 Finland
Eosinophilia
18.4
6.3
9
5
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
18.4
6.3
9
5
1XC02, ,
NOMESCO Finland
18.4
6.3
9
5
J17.2
ICD-10 Finland
Pneumonia in mycoses
+∞
6.3
6
*
2AA01, ,
NOMESCO Finland
+∞
6.3
6
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
6.3
6
*
H60.3
ICD-10 Finland
Other infective otitis externa
4.1
6.2
17
43
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
6.1
23
73
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
3.7
6.1
19
53
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.0
6.1
27
95
J01DA01
ATC
[U] cefalexin
1.8
6.1
202
1547
ZXE00
NOMESCO Finland
One hour or less
1.8
6.1
128
858
H66.9
ICD-10 Finland
Otitis media, unspecified
3.1
6.0
26
90
A03
ICPC
Fever
2.1
6.0
61
319

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
109
21
77.36
197.58
3.8
1.3
8.77
0.09
u/ml
5.73
93
13
106
53
29.11
144.82
6.2
2.4
—
—
—
0
0
203
370
12.83
124.87
5.7
1.4
—
—
—
0
0
114
9
193.13
114.82
3.0
1.7
—
—
—
0
0
127
178
11.03
93.24
4.9
1.3
1233.23
296.55
u/ml
2.19
121
165
124
248
7.44
64.69
5.4
2.3
9.53
10.94
g/l
2.47
113
228
55
50
13.02
53.38
6.0
2.8
—
—
—
0
0
151
442
5.49
50.78
3.6
2.0
—
—
—
0
0
154
506
4.86
43.87
13.1
3.4
0.80
0.83
mmol/l
2.25
149
483
40
30
15.05
43.28
1.4
1.3
0.39
0.41
g/l
0.06
24
25
40
30
15.05
43.28
1.4
1.3
2.69
2.71
g/l
0.02
23
25
123
351
5.01
41.49
2.9
1.6
—
—
—
0
0
219
974
4.78
41.14
23.8
6.5
—
—
—
0
0
39
32
13.70
39.99
1.4
1.3
—
—
—
0
0
46
52
10.13
38.12
1.5
1.9
0.80
1.03
g/l
0.33
30
44
85
199
5.42
35.79
2.8
1.6
1.20
1.34
g/l
0.20
78
180
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
43
49
9.95
35.35
3.6
1.7
—
—
—
0
0
192
896
3.77
30.85
11.0
4.6
—
—
—
0
0
68
153
5.35
29.63
1.8
2.2
1.79
1.46
g/l
1.44
56
137
123
438
3.90
29.53
1.8
1.8
—
—
—
0
0
257
1491
4.38
29.01
23.0
6.4
0.67
0.60
e9/l
4.74
241
1277
257
1496
4.35
28.74
22.9
6.4
0.05
0.04
e9/l
1.56
242
1282
32
32
10.98
28.72
1.4
1.3
—
—
—
0
0
257
1518
4.24
27.59
23.2
6.4
1.72
1.87
e9/l
1.25
244
1341
32
34
10.32
27.51
3.0
2.5
10.76
23.72
iu/ml
—
10
5
258
1544
4.18
26.78
25.5
6.6
0.23
0.20
e9/l
1.27
245
1351
57
121
5.49
26.38
1.6
1.4
—
—
—
0
0
108
401
3.53
23.65
14.2
6.3
1.05
1.04
mmol/l
0.21
102
380
260
1663
3.75
22.15
33.4
10.6
4.59
4.16
e9/l
2.05
249
1460
42
82
5.73
21.14
1.5
1.3
—
—
—
0
0
224
1348
3.10
20.36
14.0
6.5
1.21
1.21
mmol/l
0.42
218
1245
25
7
38.48
20.14
7.5
1.4
—
—
—
0
0
82
280
3.57
20.13
11.1
4.4
0.91
0.87
%
0.06
54
106
79
266
3.60
19.79
10.8
4.4
0.79
0.56
%
0.60
53
96
35
61
6.31
19.75
2.1
1.4
—
—
—
0
0
216
1292
2.98
19.51
11.4
5.3
32.71
35.44
g/l
7.86
211
1219
33
56
6.44
19.10
2.1
1.4
137.58
159.38
au/ml
0.39
12
13
29
43
7.30
19.01
11.3
3.7
—
—
—
0
0
235
1488
3.06
18.81
18.2
7.5
1.21
1.21
mmol/l
0.29
214
1291
91
365
3.07
16.91
9.8
7.3
1.57
0.71
mmol/l
1.15
78
305
91
367
3.05
16.73
9.8
7.3
7.42
7.41
ph
0.48
56
216
73
260
3.33
16.54
11.7
4.5
0.11
0.15
%
0.23
47
85
94
399
2.90
15.66
1.6
1.3
473.04
415.60
titre
0.15
23
100
162
906
2.56
15.53
9.1
4.6
7.40
7.40
ph
0.10
123
642
143
767
2.54
14.82
2.9
2.2
3.16
3.06
mg/l
0.17
128
663
42
111
4.19
14.66
5.1
2.0
22.52
21.45
s
0.15
42
105
20
9
23.56
14.40
1.1
1.0
—
—
—
0
0
70
271
3.01
13.60
12.6
4.9
0.14
0.19
%
0.16
44
84
19
9
22.31
13.49
1.3
1.2
—
—
—
0
0
68
262
3.01
13.31
11.9
8.6
—
—
—
0
0
20
12
17.65
13.15
1.7
1.2
—
—
—
0
0
55
189
3.30
13.04
4.2
4.1
—
—
—
0
0
115
589
2.47
12.81
2.3
1.4
2.24
2.53
g/l
1.01
92
360
33
81
4.42
12.63
1.7
2.4
119.11
126.66
g/l
0.62
18
62
60
225
3.04
12.26
8.0
3.7
7.43
7.42
ph
0.88
53
185
16
6
27.92
12.16
3.8
1.8
34.38
29.17
%
—
16
6
17
9
19.84
11.71
3.8
3.2
—
—
—
0
0
28
64
4.69
11.69
1.6
1.1
294.43
301.61
u/ml
0.03
14
31
23
26
9.43
11.46
1.2
1.2
—
—
—
0
0
96
476
2.44
11.28
6.1
3.3
1.06
1.69
e6/l
0.76
62
246
16
8
20.94
11.24
2.5
1.1
—
—
—
0
0
141
827
2.24
11.18
6.2
3.4
0.40
0.44
e6/l
0.06
119
608
127
714
2.27
11.16
7.3
2.6
—
—
—
0
0
50
178
3.14
11.13
5.1
3.9
24.74
24.22
mmol/l
0.42
50
178
144
857
2.22
10.96
22.1
6.5
—
—
—
0
0
212
1475
2.24
10.85
16.7
14.1
1.21
1.26
inr
0.83
185
1227
120
667
2.26
10.76
3.2
1.7
2.33
1.53
mg/l
0.49
107
536
70
305
2.65
10.74
6.5
3.8
2.54
1.79
mmol/l
0.69
62
257
193
1298
2.19
10.70
32.3
12.1
0.00
0.00
e9/l
0.08
165
1064
55
212
2.92
10.64
1.6
1.5
—
—
—
0
0
238
1761
2.29
10.12
11.9
4.9
6.55
6.74
mmol/l
0.83
230
1681
56
224
2.81
10.11
2.4
2.5
—
—
—
0
0
67
295
2.60
10.03
2.6
1.5
—
—
—
0
0
70
315
2.56
10.02
5.4
2.9
60.98
69.96
e9/l
1.32
51
234
21
26
8.55
9.99
1.6
1.2
—
—
—
0
0
132
781
2.16
9.99
5.9
3.3
—
0.00
estimate
—
0
6
14
7
20.81
9.88
5.4
3.3
—
—
—
0
0
99
524
2.28
9.86
4.1
2.7
10.31
13.08
umol/l
3.66
93
488
21
44
5.03
9.68
1.8
1.3
—
—
—
0
0
94
492
2.28
9.58
3.8
2.7
2.14
2.27
g/l
1.43
88
454
276
2202
2.62
9.51
30.7
9.1
86.70
80.69
u/l
1.30
271
2092
19
37
5.39
9.48
1.6
1.2
—
—
—
0
0
158
1018
2.07
9.40
7.0
3.6
2.31
2.35
mmol/l
2.73
150
914
69
318
2.48
9.35
6.6
3.8
7.37
7.38
ph
1.63
49
187
90
467
2.28
9.33
3.9
2.6
17.83
23.18
%
3.48
84
438
26
68
4.07
9.15
3.0
2.6
57.00
60.32
%
0.50
26
68
28
78
3.83
9.05
8.1
3.4
2.65
2.19
index
0.16
20
48
60
264
2.56
8.94
1.9
1.4
—
—
—
0
0
77
381
2.34
8.88
5.1
2.9
5.03
4.97
e9/l
0.03
63
332
20
29
7.27
8.69
1.7
2.8
45.50
40.60
%
—
8
15
241
1849
2.15
8.54
7.4
4.7
12.13
145.10
e6/l
—
8
41
178
1233
1.97
8.30
3.6
2.5
78.40
76.89
nmol/l
0.26
164
1098
151
992
1.97
8.19
6.6
3.4
54.05
121.77
e6/l
0.44
128
779
20
47
4.47
8.06
3.4
2.6
5.47
4.65
e9/l
0.48
20
47
31
103
3.22
7.69
1.9
3.7
1.79
2.61
ratio
0.42
18
63
147
972
1.93
7.69
8.9
2.6
—
—
—
0
0
64
312
2.31
7.56
11.3
7.8
117.97
121.53
g/l
0.77
64
306
66
327
2.28
7.51
2.0
1.6
—
—
—
0
0
40
158
2.75
7.34
10.2
3.9
—
—
—
0
0
43
177
2.65
7.29
14.1
8.4
15.56
15.85
%
0.30
43
170
161
1112
1.88
7.25
7.8
4.1
15.39
84.80
e6/l
3.52
132
810
100
593
1.99
7.10
4.2
2.9
552.99
547.66
mosm/kgh2o
0.09
94
522
32
114
3.00
7.07
1.9
4.2
40.35
51.83
mg/l
0.28
26
101
32
114
3.00
7.07
1.9
4.2
53.56
57.05
mg/l
0.09
27
100
11
8
14.17
6.94
1.9
1.6
—
—
—
0
0
25
78
3.39
6.85
1.6
1.6
—
—
—
0
0
13
14
9.62
6.85
2.8
1.3
41.85
60.75
ug/l
0.70
13
14
178
1286
1.84
6.80
4.8
3.0
375.24
146.35
ug/l
1.12
172
1192
10
6
17.14
6.78
1.1
1.0
—
—
—
0
0
11
9
12.59
6.63
1.1
1.0
—
—
—
0
0
18
46
4.08
6.53
1.4
1.2
1.91
3.79
u/ml
0.77
11
19
122
792
1.86
6.51
8.2
3.1
337.39
357.02
umol/l
1.30
112
701
184
1355
1.82
6.49
7.4
2.9
—
—
estimate
—
0
0
155
1084
1.82
6.49
2.7
2.2
—
—
—
0
0
56
276
2.24
6.41
3.1
2.7
32.65
37.04
u/l
0.37
49
231
18
36
5.23
6.28
1.2
1.3
—
—
—
0
0
6
0
+∞
6.27
2.7
0.0
—
—
—
0
0
41
179
2.48
6.16
1.7
1.7
—
—
—
0
0
70
384
2.05
6.08
2.0
1.6
—
—
—
0
0
12
15
8.26
5.89
2.0
2.2
2162.83
1077.07
u/ml
0.42
12
15
22
70
3.30
5.86
1.9
5.0
—
—
—
0
0
238
1943
1.83
5.49
7.4
4.5
—
2.43
—
0
6
83
503
1.87
5.35
1.7
1.7
989.50
1250.11
nmol/l
2.15
65
378
21
69
3.18
5.32
4.3
2.9
—
—
—
0
0
21
69
3.18
5.32
1.6
1.2
—
—
—
0
0
15
30
5.19
5.32
1.4
1.5
—
—
—
0
0
103
669
1.79
5.30
14.3
5.1
—
—
—
0
0
163
1219
1.67
4.96
5.2
4.0
29.83
38.91
ng/l
0.68
125
923
41
198
2.22
4.91
8.0
6.2
24.93
24.19
mmol/l
0.65
41
188
14
30
4.83
4.74
1.4
1.0
—
—
—
0
0
173
1326
1.65
4.69
2.7
2.1
96.11
96.11
pmol/l
0.00
117
697
20
69
3.02
4.69
4.2
2.0
—
—
—
0
0
16
48
3.45
4.67
2.3
1.5
—
—
—
0
0
120
843
1.67
4.55
3.5
3.1
—
—
—
0
0
14
32
4.52
4.49
1.0
1.2
—
—
—
0
0
93
612
1.73
4.48
4.9
3.9
432.36
391.50
ng/l
0.08
80
498
14
33
4.38
4.37
1.4
1.6
—
—
—
0
0
22
84
2.74
4.33
1.2
1.2
—
83.75
—
0
8
129
936
1.62
4.24
2.2
1.7
17.34
20.18
nmol/l
1.97
122
782
11
21
5.38
4.18
12.0
2.6
0.36
0.86
index
1.70
11
21
20
74
2.81
4.17
1.3
1.6
287.29
280.11
ug/g
0.05
14
48
8
10
8.17
4.08
11.6
4.5
45.13
50.10
%
—
8
10
22
87
2.64
4.06
7.7
6.0
1.17
1.32
mmol/l
0.37
22
78
244
2725
0.59
3.98
5.3
5.3
1.41
1.42
mmol/l
0.17
230
2511
98
674
1.65
3.94
4.6
3.8
—
0.25
—
0
8
48
268
1.93
3.92
2.4
2.4
14.32
9.07
ug/l
0.71
42
238
7
8
8.91
3.79
1.4
1.5
—
—
—
0
0
29
136
2.24
3.74
1.8
1.3
—
—
—
0
0
53
312
1.83
3.68
2.0
2.5
288.95
113.13
ug/g
0.95
41
246
252
2780
0.59
3.65
5.9
6.1
2.57
2.63
mmol/l
0.51
234
2568
25
112
2.33
3.58
1.9
2.3
3.05
5.31
iu/ml
—
6
33
13
37
3.62
3.44
2.1
2.2
—
—
—
0
0
11
27
4.18
3.42
1.6
3.6
1110.36
937.48
mg
0.13
11
27
155
1218
1.52
3.40
4.4
3.6
6.23
6.19
ph
0.17
87
706
248
2732
0.62
3.25
5.3
5.4
4.48
4.51
mmol/l
0.19
233
2529
185
1520
1.50
3.21
5.1
3.8
0.00
0.00
estimate
-0.00
36
306
123
929
1.52
3.21
4.3
2.2
156.12
296.12
u/l
0.86
116
883
12
35
3.52
3.14
1.7
1.9
—
—
—
0
0
33
176
1.97
3.09
2.2
2.6
—
12.95
—
0
17
9
21
4.38
3.01
2.3
1.3
—
—
—
0
0
185
1534
1.47
2.98
5.2
3.9
0.00
0.00
estimate
-0.00
36
314
43
255
1.79
2.93
3.1
2.2
0.00
0.00
estimate
—
6
54
231
2009
1.51
2.88
7.5
4.4
—
0.14
—
0
7
6
9
6.76
2.88
1.2
1.0
—
—
—
0
0
6
9
6.76
2.88
1.2
1.0
1036.00
1424.00
miu/ml
—
6
9
28
146
2.00
2.80
7.8
4.5
1.70
1.57
%
0.37
28
136
185
1548
1.45
2.76
5.3
3.9
0.00
0.01
estimate
0.50
34
295
7
14
5.08
2.74
1.0
1.1
—
—
—
0
0
26
133
2.04
2.74
8.0
4.7
0.93
0.86
%
0.56
26
123
27
141
2.00
2.69
2.7
2.4
—
—
—
0
0
81
1082
0.67
2.57
3.5
3.3
—
—
—
0
0
59
398
1.59
2.50
1.6
1.3
—
—
—
0
0
12
45
2.73
2.48
1.3
1.1
—
—
—
0
0
11
38
2.96
2.44
2.1
1.0
—
—
—
0
0
11
38
2.96
2.44
2.1
1.0
—
—
—
0
0
126
1002
1.42
2.39
5.0
3.3
1402.78
1315.32
ng/l
0.11
120
852
11
39
2.88
2.36
2.4
2.4
-0.64
0.80
mmol/l
0.83
11
39
214
1869
1.42
2.34
7.4
3.6
68.28
52.54
u/l
1.20
207
1757
51
338
1.60
2.33
4.1
4.6
3.92
49.22
ug/l
1.19
42
284
6
13
4.68
2.28
1.2
1.0
—
—
—
0
0
5
10
5.06
2.08
2.0
3.6
0.61
0.59
mmol/l
—
5
10
244
2644
0.70
2.07
6.5
6.8
40.31
39.62
mmol/mol
0.54
231
2479
11
45
2.49
1.95
4.5
2.4
30.64
32.93
pg
0.94
11
45
5
11
4.60
1.95
1.2
1.2
30.60
27.55
s
—
5
11
14
65
2.21
1.91
7.2
5.6
11.64
11.47
mmol/l
0.07
14
59
14
65
2.21
1.91
7.2
5.6
104.36
105.39
mmol/l
0.54
14
59
43
288
1.57
1.89
3.9
2.6
0.17
0.21
e6/l
0.16
43
278
9
34
2.69
1.88
1.7
1.2
—
—
—
0
0
8
28
2.90
1.87
1.6
1.9
7.74
10.84
%
—
8
28
99
785
1.37
1.84
1.8
1.4
—
—
—
0
0
8
30
2.71
1.73
2.6
1.6
—
—
—
0
0
5
13
3.89
1.72
1.4
1.1
—
—
—
0
0
10
42
2.42
1.63
1.1
1.1
—
12.54
—
0
12
14
70
2.04
1.61
1.4
1.2
—
—
—
0
0
243
2605
0.74
1.56
4.8
4.5
1.31
1.28
mmol/l
0.27
231
2390
8
33
2.46
1.54
1.9
3.1
—
—
—
0
0
289
2735
1.49
1.51
65.4
17.3
30.79
24.98
mg/l
2.47
274
2277
46
330
1.46
1.50
2.2
2.5
14.48
13.35
nmol/l
0.30
40
298
66
506
1.38
1.49
1.4
1.3
26.77
34.99
iu/ml
0.29
17
170
5
16
3.16
1.44
1.0
1.1
132.00
132.38
nmol/l
—
5
16
6
22
2.76
1.44
1.0
1.4
—
—
—
0
0
79
627
1.34
1.44
1.7
1.8
474.72
442.88
pmol/l
0.34
71
527
27
175
1.59
1.39
5.2
2.6
0.77
0.64
%
0.38
27
175
7
146
0.47
1.35
1.0
1.1
—
—
—
0
0
6
24
2.53
1.31
1.2
1.0
—
—
—
0
0
8
34
2.39
1.30
1.0
1.3
—
—
—
0
0
226
2077
1.29
1.29
4.2
4.0
14.93
14.89
pmol/l
0.08
214
1878
45
340
1.38
1.13
1.3
1.4
—
—
—
0
0
50
386
1.35
1.10
1.3
1.3
—
—
—
0
0
15
89
1.72
1.09
1.2
1.3
33.79
26.46
iu/l
—
9
77
5
21
2.40
1.09
4.8
2.3
—
—
—
0
0
10
53
1.91
1.02
1.2
1.3
—
—
—
0
0
10
53
1.91
1.02
1.3
1.4
—
—
—
0
0
80
668
1.26
1.00
4.6
4.1
1.02
1.02
kg/l
0.84
62
445
20
137
1.49
0.86
2.6
2.7
—
—
—
0
0
8
46
1.76
0.83
3.0
2.1
10.77
10.65
mmol/l
—
8
46
6
33
1.83
0.79
1.3
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
260.24
—
0
17
257
2674
0.82
0.74
5.8
5.4
5.91
6.03
mmol/l
0.70
246
2453
10
60
1.69
0.73
2.1
1.8
2.52
2.88
iu/l
—
5
25
5
28
1.80
0.66
2.4
4.0
7.70
8.67
mmol/l
—
5
28
29
226
1.31
0.64
4.2
3.6
—
—
—
0
0
109
1203
0.86
0.62
2.2
2.0
1.28
1.35
mmol/l
0.61
91
997
0
20
0.00
0.60
0.0
1.7
—
1.42
—
0
14
0
21
0.00
0.60
0.0
4.2
—
21.71
—
0
7
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
55
468
1.21
0.60
1.3
1.3
3.17
13.15
u/ml
1.78
20
187
0
23
0.00
0.58
0.0
1.9
—
—
—
0
0
95
851
1.16
0.58
5.3
4.0
0.00
0.01
estimate
0.50
34
287
5
88
0.56
0.57
1.0
1.2
—
—
—
0
0
6
37
1.63
0.56
1.7
1.9
88.13
90.22
%
—
6
37
6
39
1.55
0.53
1.0
1.3
—
—
—
0
0
7
46
1.53
0.48
2.4
7.1
6.47
7.28
mmol/l
—
7
37
7
50
1.41
0.45
2.1
2.0
—
—
—
0
0
127
1181
1.12
0.44
4.5
3.7
0.00
0.02
estimate
0.69
30
266
9
131
0.68
0.44
1.6
1.8
42.67
39.66
nmol/l
—
9
124
8
58
1.39
0.42
1.1
2.8
6.68
9.49
pmol/l
—
8
58
0
15
0.00
0.41
0.0
15.0
—
902.73
—
0
15
26
214
1.23
0.41
1.2
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
3.7
—
34.53
—
0
12
14
107
1.32
0.38
2.4
3.6
221.00
246.39
mg/l
—
8
41
5
37
1.36
0.37
8.8
3.4
5.80
3.24
nmol/l
—
5
37
70
636
1.13
0.36
1.3
1.2
0.88
1.38
u/ml
0.63
22
176
113
1061
1.10
0.32
4.6
3.4
7.05
8.07
mmol/l
1.75
104
882
111
1042
1.10
0.32
5.2
4.2
17.37
7.66
mg/mmol
1.20
79
667
26
299
0.86
0.27
2.2
1.5
—
—
—
0
0
5
72
0.69
0.26
1.8
1.5
—
—
—
0
0
9
77
1.17
0.24
1.2
1.4
—
270.91
—
0
35
6
82
0.73
0.24
2.0
1.5
—
—
—
0
0
15
124
1.22
0.24
3.8
1.9
—
—
—
0
0
108
1026
1.08
0.24
4.4
3.5
79.96
50.35
mg/l
0.66
77
690
7
93
0.75
0.22
1.3
1.1
1.84
1.54
g/l
—
7
93
5
42
1.19
0.21
4.8
3.2
1.23
1.18
mmol/l
—
5
42
5
42
1.19
0.21
4.8
3.2
4.06
4.03
mmol/l
—
5
42
5
42
1.19
0.21
4.8
3.2
110.20
105.21
mmol/l
—
5
42
0
14
0.00
0.20
0.0
10.9
—
0.66
—
0
14
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
20
175
1.15
0.19
1.1
1.3
—
—
—
0
0
91
869
1.07
0.17
4.3
3.2
0.00
0.00
estimate
0.50
31
247
6
78
0.76
0.15
1.0
1.6
—
—
—
0
0
6
79
0.76
0.15
2.0
1.5
—
—
—
0
0
6
80
0.75
0.15
2.0
1.5
—
—
—
0
0
6
80
0.75
0.15
2.2
1.5
—
—
—
0
0
8
96
0.83
0.14
1.5
1.2
0.83
0.90
g/l
—
8
96
254
2511
1.05
0.11
5.3
5.0
1.86
1.99
mu/l
1.13
238
2296
284
2816
1.06
0.11
41.1
15.4
—
—
—
0
0
21
227
0.92
0.09
1.4
1.4
—
—
—
0
0
6
58
1.04
0.08
2.0
1.6
—
—
—
0
0
9
87
1.04
0.07
1.1
1.1
—
—
—
0
0
10
89
1.13
0.07
1.2
1.2
14.24
8.08
u/l
—
5
69
8
91
0.88
0.07
13.3
13.5
—
—
—
0
0
14
129
1.09
0.05
1.1
1.3
—
—
—
0
0
14
134
1.05
0.00
1.0
1.5
0.18
0.35
mg/l
—
7
56
80
806
0.99
0.00
3.3
3.3
0.61
0.80
ug/l
2.07
58
533
22
218
1.01
0.00
1.2
1.4
—
—
—
0
0
13
133
0.98
0.00
1.2
1.1
—
—
—
0
0
10
95
1.05
0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
1.19
—
0
6
0
6
0.00
0.00
0.0
1.7
—
59.00
—
0
6
0
6
0.00
0.00
0.0
2.0
—
17.30
—
0
6
0
7
0.00
-0.00
0.0
4.6
—
24.07
—
0
7
134
1340
1.00
-0.00
5.2
5.7
1.86
2.52
ug/l
1.26
119
1205
0
5
0.00
-0.00
0.0
1.0
—
20.20
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
47.09
—
0
8
8
80
1.00
-0.00
7.4
4.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
2664.43
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
0.00
—
0
9
6
64
0.94
-0.00
1.2
1.4
—
—
—
0
0
6
68
0.88
-0.00
8.8
4.4
30.17
29.12
mg/l
—
6
51
0
5
0.00
-0.00
0.0
6.4
—
6.33
—
0
5

Mortality – FinRegistry

Association

Association between endpoint AB1_ASPERGILLOSIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ASPERGILLOSIS 4.089 [3.03, 5.52] < 0.001
Birth year 0.994 [0.99, 1.0] 0.199

During the follow-up period (1.1.1998 — 31.12.2019), 157 out of 432 females with AB1_ASPERGILLOSIS died.

Males

Parameter HR [95% CI] p-value
AB1_ASPERGILLOSIS 5.317 [4.05, 6.99] < 0.001
Birth year 0.988 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 377 out of 732 males with AB1_ASPERGILLOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ASPERGILLOSIS.

N-year risk Females Males
1 0.413% 0.945%
5 2.448% 6.264%
10 6.095% 14.861%
15 11.683% 27.194%
20 19.595% 41.719%

Relationships between endpoints

Index endpoint: AB1_ASPERGILLOSIS – Aspergillosis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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