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Atypical virus infections of central nervous system

EFO Endpoint Browser PheWeb

AB1_ATYPICAL_CNS_VIRUS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A81
  • Hospital discharge: ICD-8 — 04[5-]
  • Cause of death: ICD-10 — A81
  • Cause of death: ICD-8 — 04[5-]

2 out of 7 registries used, show all original rules.

372

4. Check minimum number of events

None

372

5. Include endpoints

None

372

6. Filter based on genotype QC (FinnGen only)

340

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2894 1340 1530
Only index persons 2514 1171 1343
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.05 0.04 0.05
Median age at first event (years)
Whole population 23.36 28.47 18.42
Only index persons 20.77 26.75 15.55

-FinnGen-

Key figures

All Female Male
Number of individuals 340 202 138
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 26.32 26.57 25.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
353
Matched controls
3530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
249.7
209
*
04597
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Suspecta
+∞
53.5
50
*
A81.0
ICD-10 Finland
Creutzfeldt-Jakob disease
+∞
32.8
31
*
A81.2
ICD-10 Finland
Progressive multifocal leukoencephalopathy
+∞
27.4
26
*
04500
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Coxsackie virus
+∞
15.7
15
*
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
33.6
10.4
13
*
A81.9
ICD-10 Finland
Atypical virus infection of central nervous system, unspecified
+∞
8.4
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
7.8
95
534
A81.8
ICD-10 Finland
Other atypical virus infections of central nervous system
+∞
7.3
7
*
J01MA12
ATC
levofloxacin; systemic
2.1
7.2
74
389
N03AX12
ATC
[U] gabapentin; oral
2.1
7.0
73
386
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
6.7
68
356
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.7
6.5
21
60
F02.19*A81.0
ICD-10 Finland
Dementia in Jakob-Creutzfeldt's disease without information on additional symptoms
+∞
6.3
6
*
N03AG01
ATC
valproic acid; systemic, rectal
2.9
6.0
29
107

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
34
106
3.44
9.30
3.8
3.3
24.92
24.93
mmol/l
0.01
28
99
25
64
4.13
9.03
1.5
1.2
—
—
—
0
0
204
1457
1.95
8.50
6.7
6.0
1.21
1.21
mmol/l
0.03
181
1334
19
31
6.41
7.65
1.5
1.1
—
—
—
0
0
23
74
3.26
6.00
1.3
1.1
5.13
6.33
e6/l
0.11
16
58
64
343
2.06
5.86
3.8
2.8
1.95
1.82
%
0.37
56
317
209
1613
1.72
5.79
7.5
7.1
1.21
1.21
mmol/l
0.02
162
1385
34
142
2.54
5.58
3.9
3.2
—
—
—
0
0
196
1510
1.67
5.26
8.3
6.5
56.87
57.14
%
0.11
189
1441
51
262
2.11
5.21
3.6
3.0
75.49
73.60
e9/l
0.13
36
194
42
201
2.24
5.11
3.9
3.1
7.42
7.42
ph
0.12
34
166
220
2590
0.60
4.89
27.4
19.3
332.99
332.43
g/l
0.45
220
2582
192
1505
1.60
4.55
9.1
6.5
0.67
0.73
%
0.98
184
1403
21
76
2.87
4.53
1.6
1.2
2424.25
159.32
e6/l
0.45
16
62
53
292
1.96
4.47
6.8
4.1
7.39
7.35
ph
2.22
32
205
207
1665
1.59
4.30
8.1
6.5
1.99
1.91
e9/l
0.30
184
1471
191
1511
1.58
4.24
8.8
6.4
2.83
2.90
%
0.15
182
1416
166
1272
1.58
4.23
4.6
3.7
43.22
84.71
ng/l
0.42
121
899
14
42
3.43
4.08
1.2
1.8
—
—
—
0
0
116
824
1.61
4.04
5.3
4.1
—
—
—
0
0
190
1513
1.55
4.02
9.3
6.5
8.83
8.87
%
0.06
182
1422
224
1856
1.57
3.93
4.5
4.9
6.67
6.70
mmol/l
0.09
214
1774
221
1826
1.56
3.92
13.9
10.3
4.01
3.98
e9/l
0.06
192
1602
208
1696
1.55
3.91
8.4
6.7
0.19
0.19
e9/l
0.01
180
1488
202
1639
1.54
3.87
8.3
6.5
0.56
0.57
e9/l
0.31
176
1411
65
402
1.76
3.81
5.3
5.8
1.01
1.02
mmol/l
0.12
59
373
184
1468
1.53
3.77
19.5
11.5
1.25
1.20
inr
0.70
162
1193
202
1646
1.53
3.74
8.4
6.5
0.04
0.04
e9/l
1.85
177
1417
0
93
0.00
3.51
0.0
3.1
—
1.53
—
0
88
12
33
3.73
3.32
1.8
1.1
—
—
—
0
0
80
543
1.61
3.30
3.6
3.3
0.81
0.82
mmol/l
0.43
74
514
103
742
1.55
3.29
2.4
2.1
3.14
3.10
mg/l
0.05
92
647
131
1002
1.49
3.13
3.3
2.3
—
—
—
0
0
7
12
5.93
3.03
2.9
2.3
—
—
—
0
0
121
917
1.49
3.01
1.9
1.7
21.28
21.11
nmol/l
0.04
94
769
10
26
3.93
3.00
1.0
1.2
—
—
—
0
0
114
861
1.48
2.86
3.0
2.7
340.85
340.71
umol/l
0.00
97
754
130
1008
1.46
2.85
2.4
2.6
56.87
62.15
u/l
0.51
117
935
43
258
1.76
2.80
4.4
3.6
1.24
1.23
mmol/l
0.42
33
225
230
1991
1.45
2.73
5.2
4.4
14.33
3545.22
e6/l
—
6
32
71
493
1.55
2.63
2.8
2.3
2.30
2.37
g/l
0.49
66
450
14
56
2.56
2.56
1.4
2.2
—
—
—
0
0
16
70
2.35
2.45
1.3
1.6
—
—
—
0
0
24
126
1.97
2.37
1.5
1.9
1.62
3.12
ug/l
0.29
19
117
36
216
1.74
2.36
1.2
1.4
—
31.01
—
0
14
125
994
1.40
2.30
4.0
3.9
7.39
7.40
ph
0.42
88
696
170
1423
1.38
2.29
5.6
4.8
35.22
36.19
g/l
1.28
157
1346
51
340
1.58
2.26
1.5
1.7
—
—
—
0
0
92
695
1.44
2.25
2.8
2.6
3.97
6.66
e6/l
1.34
80
638
9
29
3.16
2.24
4.3
3.1
—
—
—
0
0
17
330
0.49
2.22
1.7
1.4
—
—
—
0
0
13
54
2.46
2.22
1.2
1.4
—
—
—
0
0
81
600
1.45
2.20
2.5
2.8
548.69
527.15
mosm/kgh2o
0.33
65
525
52
352
1.56
2.16
5.4
8.3
0.94
1.05
mmol/l
0.05
45
303
166
1398
1.35
2.10
2.3
2.1
105.91
97.79
pmol/l
1.12
92
703
20
103
2.00
2.10
2.2
2.1
1311.77
353.94
ug/l
0.52
20
96
10
37
2.75
2.08
1.3
1.1
—
—
—
0
0
138
1133
1.36
2.05
4.5
3.3
2.35
2.36
mmol/l
0.78
125
1034
52
358
1.53
2.01
5.5
8.2
7.43
7.42
ph
0.91
32
198
19
98
1.99
1.99
1.6
4.0
1.04
2.23
ratio
—
9
52
65
471
1.47
1.97
1.8
1.8
29.34
29.24
s
0.06
65
461
268
2447
1.40
1.93
10.2
8.5
79.09
78.44
u/l
0.08
252
2313
66
482
1.45
1.92
2.1
1.7
1102.66
1223.05
nmol/l
0.52
49
366
20
107
1.92
1.90
1.6
4.4
40.18
39.24
mg/l
0.03
13
91
20
107
1.92
1.90
1.6
4.4
117.41
46.69
mg/l
0.38
13
90
18
93
1.99
1.88
1.2
1.7
—
—
—
0
0
92
716
1.39
1.88
1.6
1.7
1.31
1.23
mg/l
0.06
63
561
168
1435
1.33
1.87
3.4
2.7
—
—
estimate
—
0
0
18
94
1.96
1.83
1.2
1.7
—
—
—
0
0
18
94
1.96
1.83
1.2
1.7
—
—
—
0
0
46
316
1.52
1.81
2.8
2.0
358.34
380.51
nmol/l
0.36
41
301
8
29
2.80
1.80
2.3
1.8
31.70
42.26
%
—
8
29
264
2416
1.37
1.78
4.7
4.3
14.98
14.75
pmol/l
0.78
235
2219
13
61
2.17
1.73
1.3
1.5
—
—
—
0
0
37
245
1.57
1.71
3.6
3.5
91.84
79.76
ng/l
0.27
26
214
24
143
1.73
1.66
1.2
1.7
—
12.08
—
0
5
50
357
1.47
1.64
1.8
1.7
—
—
—
0
0
5
14
3.61
1.62
1.2
1.0
127.40
134.64
nmol/l
—
5
14
42
292
1.50
1.57
1.6
1.4
—
—
—
0
0
36
242
1.54
1.57
2.4
2.3
5.71
7.67
ug/l
0.47
30
218
5
15
3.37
1.53
2.6
3.6
17.60
13.67
mu/l
—
5
15
20
116
1.77
1.52
5.7
3.7
459.89
168.86
mg/l
—
9
49
33
220
1.55
1.50
2.7
2.5
—
—
—
0
0
41
289
1.47
1.45
4.4
5.2
0.45
0.49
%
0.07
20
84
20
118
1.74
1.44
1.1
1.3
—
—
—
0
0
16
88
1.86
1.44
1.3
1.8
—
—
—
0
0
194
1730
1.27
1.42
8.2
6.8
10.12
11.16
umol/l
1.16
182
1651
34
232
1.52
1.40
1.3
1.6
—
—
—
0
0
9
41
2.23
1.38
1.3
1.2
—
—
—
0
0
9
41
2.23
1.38
3.3
4.4
318.56
371.14
umol/l
—
9
36
40
284
1.46
1.37
4.9
5.3
0.00
0.13
%
2.18
15
75
6
23
2.64
1.37
1.0
1.1
—
—
—
0
0
42
302
1.44
1.35
4.9
5.2
0.82
0.86
%
0.03
17
94
18
106
1.74
1.32
1.9
2.9
1.17
1.44
mg/l
1.40
18
96
35
244
1.48
1.32
3.9
3.6
—
—
—
0
0
5
18
2.80
1.29
1.0
1.2
—
—
—
0
0
27
179
1.55
1.28
3.1
5.0
—
—
—
0
0
5
117
0.42
1.27
1.0
1.1
—
0.66
—
0
15
8
36
2.25
1.25
2.8
3.4
—
—
—
0
0
26
172
1.55
1.24
2.4
1.7
—
—
—
0
0
162
1431
1.24
1.23
14.0
11.7
0.00
0.00
e9/l
0.61
135
1178
16
94
1.74
1.19
1.3
1.7
—
—
—
0
0
12
64
1.91
1.19
1.7
1.7
—
—
—
0
0
8
38
2.13
1.19
1.4
1.9
-0.76
0.89
mmol/l
—
8
38
11
57
1.96
1.18
3.3
2.6
1.67
3.16
mmol/l
—
6
36
10
50
2.03
1.17
8.2
3.1
4.19
4.67
e9/l
—
10
50
42
312
1.39
1.15
6.0
8.7
124.48
122.71
g/l
0.20
42
305
109
928
1.25
1.14
3.0
3.0
—
—
—
0
0
7
30
2.36
1.13
1.0
1.3
—
—
—
0
0
7
140
0.49
1.11
1.3
1.1
—
—
—
0
0
8
41
1.97
1.09
1.3
1.3
—
—
—
0
0
5
21
2.40
1.09
15.8
15.8
751.40
983.33
nmol/l
—
5
21
317
3048
1.39
1.09
21.8
15.1
22.07
22.20
mg/l
0.02
275
2484
165
1476
1.22
1.08
2.7
2.5
78.30
77.35
nmol/l
0.14
144
1331
23
154
1.53
1.06
2.4
2.4
—
—
—
0
0
50
388
1.34
1.06
1.4
1.5
—
—
—
0
0
143
1263
1.22
1.05
2.1
2.1
—
—
—
0
0
5
22
2.29
1.03
1.2
1.5
—
—
—
0
0
5
22
2.29
1.03
1.4
1.2
—
—
—
0
0
9
47
1.94
1.03
1.9
1.9
—
—
—
0
0
39
293
1.37
1.01
5.3
5.7
0.00
0.14
%
0.66
16
72
5
23
2.19
0.98
1.2
1.2
—
—
—
0
0
325
3149
1.40
0.94
19.8
13.3
—
—
—
0
0
20
134
1.52
0.94
1.2
1.3
—
—
—
0
0
11
63
1.77
0.91
1.0
1.1
—
—
—
0
0
108
941
1.21
0.90
4.3
3.8
0.00
0.01
estimate
0.69
39
322
127
1125
1.20
0.89
3.2
3.6
37.80
33.12
u/l
0.36
121
1061
77
650
1.24
0.87
1.7
1.7
491.93
21234563.90
pmol/l
0.50
55
551
55
448
1.27
0.84
2.1
1.8
—
—
—
0
0
49
394
1.28
0.83
1.2
1.2
—
—
—
0
0
8
46
1.76
0.83
1.0
1.2
—
—
—
0
0
6
32
1.89
0.82
1.0
1.3
—
—
—
0
0
6
32
1.89
0.82
1.5
2.9
—
—
—
0
0
131
1453
0.84
0.81
2.3
2.0
1.31
1.39
mmol/l
0.46
93
1235
39
305
1.31
0.81
1.3
1.4
—
—
—
0
0
56
460
1.26
0.80
1.3
1.3
—
—
—
0
0
10
58
1.75
0.80
1.1
1.4
—
—
—
0
0
6
33
1.83
0.79
1.0
1.1
—
—
—
0
0
6
34
1.78
0.76
1.7
1.8
92.32
90.69
%
—
6
34
49
399
1.26
0.76
1.9
2.3
678.28
111.59
ug/g
0.57
36
324
16
108
1.50
0.75
1.6
1.3
269.90
293.17
ug/g
—
10
68
5
24
2.10
0.75
1.4
1.1
185.60
415.58
nmol/l
—
5
19
234
2207
1.18
0.74
3.9
3.5
53.54
48.65
u/l
0.33
219
2092
55
456
1.24
0.74
2.3
1.9
—
—
—
0
0
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
10
60
1.69
0.73
3.9
2.7
—
—
—
0
0
5
26
1.94
0.71
1.2
3.2
2630.20
975.42
mg
—
5
26
9
58
1.57
0.70
1.0
1.1
—
—
—
0
0
158
1450
1.16
0.70
3.3
2.9
139.98
118.43
ug/l
0.82
145
1354
23
170
1.38
0.69
2.8
2.4
0.00
4.74
estimate
—
9
53
82
934
0.84
0.68
2.9
3.0
—
0.12
—
0
17
7
43
1.64
0.67
1.3
1.3
121.86
383.63
pmol/l
—
7
38
226
2136
1.16
0.66
5.0
4.5
—
3.26
—
0
6
10
62
1.63
0.65
3.2
6.5
105.20
105.64
mmol/l
—
10
55
10
62
1.63
0.65
1.0
1.1
—
—
—
0
0
10
62
1.63
0.65
3.2
6.5
10.10
10.62
mmol/l
—
10
55
5
29
1.73
0.64
1.2
1.4
21.42
21.86
ng/l
—
5
29
48
400
1.23
0.63
1.4
1.4
—
—
—
0
0
13
88
1.50
0.61
1.1
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.6
—
4.06
—
0
20
0
21
0.00
0.60
0.0
1.7
—
73.62
—
0
21
114
1032
1.15
0.60
3.7
3.2
369.38
97.48
e6/l
0.36
90
780
49
415
1.21
0.56
4.2
3.0
8.75
4.90
e9/l
0.34
40
368
8
124
0.64
0.55
1.0
1.2
0.82
0.88
g/l
—
8
124
6
38
1.59
0.54
1.2
1.2
—
—
—
0
0
9
61
1.49
0.54
1.3
1.1
—
—
—
0
0
9
61
1.49
0.54
1.3
1.1
—
—
—
0
0
129
1188
1.14
0.52
4.3
3.9
51.87
97.07
e6/l
0.65
96
828
21
163
1.31
0.49
1.1
1.1
—
132.20
—
0
5
86
775
1.15
0.48
6.6
5.2
—
—
—
0
0
8
119
0.66
0.46
1.0
1.1
1.53
1.53
g/l
—
8
119
12
86
1.41
0.45
3.5
6.2
1.37
1.19
mmol/l
0.43
12
75
24
193
1.26
0.44
5.0
7.5
25.92
24.81
mmol/l
0.76
24
184
9
130
0.68
0.44
2.0
1.8
—
—
—
0
0
123
1141
1.12
0.44
3.5
3.4
7.52
7.70
mmol/l
0.14
95
969
82
742
1.14
0.43
3.9
3.9
1.02
1.02
kg/l
0.53
60
491
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
19
149
1.29
0.42
1.3
1.4
0.25
0.30
mg/l
—
9
61
293
2998
0.87
0.42
7.0
6.5
39.11
39.25
mmol/mol
0.11
267
2832
5
32
1.57
0.42
1.6
3.4
2.90
3.44
nmol/l
—
5
32
5
32
1.57
0.42
1.2
1.4
1.39
1.30
promille
—
5
27
10
70
1.44
0.42
8.5
3.0
56.40
59.86
%
—
10
70
0
15
0.00
0.41
0.0
1.1
—
7.42
—
0
15
40
344
1.18
0.41
1.2
1.5
—
—
—
0
0
94
863
1.12
0.40
1.4
1.4
—
—
—
0
0
14
106
1.33
0.39
2.1
2.6
24.18
24.93
mmol/l
0.35
14
106
295
2881
1.15
0.39
6.1
5.4
1.90
1.88
mu/l
0.11
264
2666
5
36
1.39
0.38
2.6
1.9
12.48
10.75
%
—
5
36
9
67
1.35
0.38
2.0
2.8
7.31
8.52
pmol/l
—
9
67
21
171
1.24
0.36
1.4
1.2
—
—
—
0
0
103
956
1.11
0.36
3.3
3.2
0.00
0.01
estimate
0.74
32
285
6
43
1.40
0.35
1.2
1.1
—
—
—
0
0
71
647
1.12
0.34
4.0
2.6
2.47
2.45
mmol/l
0.61
62
589
6
44
1.37
0.34
1.8
2.1
—
—
—
0
0
83
764
1.11
0.34
1.4
1.3
0.52
1.12
u/ml
2.11
21
215
6
46
1.31
0.33
1.7
1.7
—
—
—
0
0
138
1306
1.09
0.33
3.8
3.6
0.00
0.02
estimate
0.78
34
290
7
100
0.69
0.31
10.1
7.1
—
—
—
0
0
10
75
1.34
0.30
2.7
2.6
8.13
8.01
kpa
—
10
75
54
489
1.12
0.30
1.2
1.4
741.82
530.67
titre
0.38
11
120
43
384
1.14
0.29
1.2
1.3
—
—
—
0
0
23
269
0.84
0.28
3.6
2.5
6.00
6.12
ph
0.22
12
180
8
62
1.30
0.28
1.5
1.5
—
—
—
0
0
74
685
1.10
0.28
1.7
1.5
2.24
2.51
g/l
0.65
45
417
94
881
1.09
0.27
3.8
3.1
0.26
0.48
e6/l
1.03
72
637
103
970
1.09
0.27
7.6
6.3
—
—
—
0
0
22
255
0.85
0.25
1.9
1.9
3.68
3.55
mmol/l
0.29
17
200
12
96
1.26
0.25
1.2
1.2
—
—
—
0
0
52
564
0.91
0.23
2.8
3.0
0.61
0.76
ug/l
0.97
28
317
5
39
1.29
0.23
1.0
1.3
—
—
—
0
0
143
1374
1.07
0.22
3.5
3.4
6.27
6.18
ph
0.46
88
786
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
4.5
—
7.27
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
308
3041
1.10
0.21
6.0
5.2
6.03
5.96
mmol/l
0.30
270
2817
325
3280
0.88
0.20
15.6
12.4
27.41
27.03
u/l
0.16
311
3194
6
50
1.20
0.20
2.8
2.0
0.87
0.98
%
—
6
33
72
762
0.93
0.19
4.0
3.7
—
0.00
—
0
5
17
195
0.87
0.18
1.1
1.1
—
—
—
0
0
29
262
1.12
0.18
9.6
8.8
—
—
—
0
0
29
319
0.90
0.17
4.4
3.3
7.37
7.39
ph
0.88
14
181
314
3169
0.92
0.16
6.3
6.1
2.77
2.76
mmol/l
0.02
284
2952
29
317
0.91
0.15
4.2
3.3
5.50
5.73
kpa
0.69
29
308
9
81
1.11
0.15
4.3
2.3
74.39
60.63
%
—
9
81
89
927
0.95
0.15
4.1
4.8
1.65
2.24
ug/l
0.67
75
830
47
441
1.08
0.14
6.2
7.0
103.87
103.99
mmol/l
0.06
47
441
54
510
1.07
0.14
3.6
2.9
1.50
2.12
e6/l
0.52
30
242
33
305
1.09
0.14
2.8
2.3
0.00
0.05
estimate
—
10
63
10
84
1.20
0.14
1.3
1.3
—
—
—
0
0
34
316
1.08
0.13
1.6
1.6
—
—
—
0
0
56
589
0.94
0.13
4.0
3.9
154.57
281.51
ng/l
0.37
42
457
15
168
0.89
0.12
1.5
1.8
—
—
—
0
0
302
2994
1.06
0.11
4.9
4.5
1.41
1.31
mmol/l
0.56
269
2770
62
595
1.05
0.10
1.4
1.3
15.63
11.65
u/ml
0.17
23
240
15
165
0.91
0.09
1.1
1.1
—
—
—
0
0
128
1307
0.97
0.09
3.8
3.3
—
—
—
0
0
112
1094
1.03
0.09
3.7
3.4
36.15
46.58
mg/l
0.33
58
688
114
1117
1.03
0.07
4.8
4.1
6.45
8.11
mg/mmol
0.26
62
683
17
157
1.09
0.07
2.5
2.1
9.18
9.07
iu/ml
—
5
45
21
221
0.95
0.04
1.3
1.3
—
—
—
0
0
12
111
1.08
0.04
1.6
1.3
—
—
—
0
0
27
262
1.03
0.02
1.4
1.2
—
—
—
0
0
228
2272
1.01
0.01
4.7
4.1
—
0.17
—
0
6
66
653
1.01
0.01
1.5
1.3
54.96
36.27
iu/ml
0.29
21
204
10
94
1.07
0.01
1.0
1.1
—
—
—
0
0
14
134
1.05
0.00
2.9
5.0
0.96
0.90
%
0.17
14
123
14
146
0.96
0.00
2.6
4.8
1.96
1.59
%
0.82
14
135
33
336
0.98
0.00
5.7
4.6
15.61
19.34
ug/l
0.09
26
281
173
1724
1.01
0.00
4.1
3.8
0.00
4.63
estimate
0.50
40
351
171
1706
1.00
0.00
4.1
3.8
0.00
0.00
estimate
0.50
39
347
174
1737
1.00
0.00
4.2
3.8
0.00
0.02
estimate
0.79
36
321
10
104
0.96
0.00
1.8
2.8
—
—
—
0
0
312
3125
0.99
0.00
6.0
5.4
4.75
4.71
mmol/l
0.25
284
2927
311
3114
0.99
0.00
5.8
5.3
1.46
1.48
mmol/l
0.31
280
2899
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
50.29
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
62.17
—
0
6
5
49
1.02
-0.00
1.0
1.3
0.50
0.57
nmol/l
—
5
43
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
2.00
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
0.98
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
1.82
—
0
5
0
8
0.00
-0.00
0.0
1.9
—
1.18
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
6.06
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_ATYPICAL_CNS_VIRUS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ATYPICAL_CNS_VIRUS 4.8 [2.84, 8.11] < 0.001
Birth year 0.991 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 229 females with AB1_ATYPICAL_CNS_VIRUS died.

Males

Parameter HR [95% CI] p-value
AB1_ATYPICAL_CNS_VIRUS 8.359 [4.15, 16.85] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 186 males with AB1_ATYPICAL_CNS_VIRUS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ATYPICAL_CNS_VIRUS.

N-year risk Females Males
1 0.359% 1.382%
5 2.327% 8.753%
10 5.99% 22.142%
15 11.43% 38.663%
20 19.64% 57.268%

Relationships between endpoints

↥

Index endpoint: AB1_ATYPICAL_CNS_VIRUS – Atypical virus infections of central nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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