Viral infections of the central nervous system

AB1_VIRAL_CNS

viral meningitis: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A80-A89
  • Hospital discharge: ICD-9 04[5-9]|071|06[2-4]
  • Hospital discharge: ICD-8 04[0-3]|06[2-5]|071
  • Cause of death: ICD-10 A80-A89
  • Cause of death: ICD-9 04[5-9]|071|06[2-4]
  • Cause of death: ICD-8 04[0-3]|06[2-5]|071

2 out of 7 registries used, show all original rules.

2991

4. Check minimum number of events

None

2991

5. Include endpoints

3339

6. Filter based on genotype QC (FinnGen only)

2996

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2

Similar endpoints

List of similar endpoints to Viral infections of the central nervous system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26420 13206 13059
Only index persons 23392 11811 11581
Unadjusted period prevalence (%)
Whole population 0.37 0.38 0.36
Only index persons 0.44 0.43 0.44
Median age at first event (years)
Whole population 31.76 34.52 28.71
Only index persons 30.31 33.40 27.16

-FinnGen-

Key figures

All Female Male
Number of individuals 2996 1795 1201
Unadjusted period prevalence (%) 0.60 0.64 0.55
Median age at first event (years) 36.97 35.04 39.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3123
Matched controls
31229
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
0499X
ICD-9 Finland
Other non-arthropod-borne viral diseases of central nervous system, Unspecified non-arthropod-borne viral diseases of central nervous system
+∞
315.0
297
*
TAB00
NOMESCO Finland
Lumbar puncture
9.3
307.7
526
665
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
307.7
1121
*
A86
ICD-10 Finland
Unspecified viral encephalitis
9315.3
307.7
731
*
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
220.5
209
*
G03.9
ICD-10 Finland
Meningitis, unspecified
48.0
205.5
120
26
AA1AD
NOMESCO Finland
CT of head and brain
3.0
175.8
1214
5537
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
47.4
172.6
101
22
R51.80
ICD-10 Finland
Headache
3.2
167.1
861
3315
5AB01, ,
NOMESCO Finland
52.6
125.7
72
14
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.5
120.4
460
1451
06599
ICD-8 Finland
Viral encephalitis, unspecified
+∞
110.0
105
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.6
109.3
218
416
XA800
NOMESCO Finland
Neuropsychological investigation
4.3
92.3
255
637
R50.9
ICD-10 Finland
Fever, unspecified
2.5
86.2
648
2935
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
861.6
86.0
84
*
04300, ,
ICD-8 Finland
+∞
77.4
74
*
A84.9
ICD-10 Finland
Tick-borne viral encephalitis, unspecified
756.2
75.6
74
*
N03AX14
ATC
levetiracetam; systemic
4.8
72.1
166
358
A87.8
ICD-10 Finland
Other viral meningitis
+∞
69.0
66
*
R41.0
ICD-10 Finland
Disorientation, unspecified
4.8
66.6
153
329
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
66.1
1511
10298
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.4
63.3
239
738
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
319.1
61.6
62
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.4
60.6
232
723
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
60.6
590
2951
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
313.7
60.5
61
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
57.6
531
2592
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
56.7
392
1684
04499
ICD-8 Finland
Late effects of actue poliomyelitis
+∞
55.4
53
*
A89
ICD-10 Finland
Unspecified viral infection of central nervous system
275.7
53.3
54
*
04597
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Suspecta
+∞
52.2
50
*
B91
ICD-10 Finland
Sequelae of poliomyelitis
19.3
51.0
40
21
A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
50.1
48
*
A85.8
ICD-10 Finland
Other specified viral encephalitis
+∞
47.0
45
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
46.8
1332
9382
N03AX16
ATC
[U] pregabalin
1.9
46.1
746
4439
N71
ICPC
Meningitis/encephalitis
238.5
46.1
47
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
43.2
790
4873
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.5
42.8
153
455
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.7
42.3
99
216
R51
ICD-10 Finland
Headache
2.7
41.7
247
980
F05.9
ICD-10 Finland
Delirium, unspecified
4.6
41.4
99
220
B34.9
ICD-10 Finland
Viral infection, unspecified
3.4
41.0
149
448
0498X
ICD-9 Finland
Other non-arthropod-borne viral diseases of central nervous system, Other specified non-arthropod-borne viral diseases of central nervous system
+∞
40.7
39
*
J05AB11
ATC
valaciclovir; oral
2.0
40.0
510
2787
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
7.1
39.8
60
86
N03AX12
ATC
[U] gabapentin; oral
2.0
39.7
532
2957
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
39.1
704
4302
H02AB06
ATC
prednisolone; systemic
1.6
38.7
1457
10871
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.1
38.2
107
269
R42
ICD-10 Finland
Dizziness and giddiness
1.8
37.9
716
4435
N03AX18
ATC
lacosamide; systemic
7.0
36.9
56
81
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
36.6
1188
8505
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
35.5
496
2788
N03AF02
ATC
oxcarbazepine; oral
3.2
34.9
141
453
G41.9
ICD-10 Finland
Status epilepticus, unspecified
9.2
34.8
42
46
R4120
NOMESCO Finland
Occupational therapy
2.4
34.6
244
1050
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
33.9
338
1683
Z2445
NOMESCO Finland
Psychologist
2.8
32.3
169
628
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.9
31.9
96
254
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.0
31.2
89
227
A81.0
ICD-10 Finland
Creutzfeldt-Jakob disease
316.0
30.9
31
*
G44.2
ICD-10 Finland
Tension-type headache
1.9
30.8
473
2734
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
30.5
1335
10134
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
4.6
29.0
69
153
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
28.7
276
1351
B94.1
ICD-10 Finland
Sequelae of viral encephalitis
104.4
28.7
31
*
B00.4
ICD-10 Finland
Herpesviral encephalitis
151.4
28.7
30
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.1
28.3
302
1539
ZX120
NOMESCO Finland
Intravenous
2.1
28.0
291
1467
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
64.6
27.9
32
5
N03AG01
ATC
valproic acid; systemic, rectal
2.3
27.6
217
979
XA400
NOMESCO Finland
EEG
7.4
27.6
40
55
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
27.2
833
5792
A81.2
ICD-10 Finland
Progressive multifocal leukoencephalopathy
+∞
27.1
26
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
26.9
1019
7434
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
26.7
403
2309
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.9
26.7
59
123
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
26.3
616
4002
J01AA02
ATC
doxycycline; systemic
1.6
25.9
2299
19994
N01
ICPC
Headache
1.8
25.9
407
2360
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
25.7
1319
10241
R4150
NOMESCO Finland
Neuropsychological rehabilitation
5.3
25.6
51
97
R11
ICD-10 Finland
Nausea and vomiting
2.0
25.0
296
1563
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
24.1
116
412
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
24.0
469
2897
M03BX02
ATC
tizanidine; oral
1.5
23.5
1873
15751
J01DB01
ATC
cefalexin; oral
1.6
23.3
2519
22554
A84.1
ICD-10 Finland
Central European tick-borne encephalitis
+∞
22.9
22
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
22.9
680
4666
N03AF01
ATC
carbamazepine; oral, rectal
2.4
22.8
159
680
N05BA01
ATC
diazepam; systemic, rectal
1.8
22.7
383
2265
R53
ICD-10 Finland
Malaise and fatigue
1.5
22.6
783
5560
P01AB01
ATC
metronidazole; oral, rectal
1.5
22.4
1168
9022
N05BA04
ATC
oxazepam; oral
1.5
22.4
778
5528
A02BC02
ATC
pantoprazole; systemic
1.5
22.2
1992
17042
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
22.1
1587
13017
N06AA09
ATC
amitriptyline; systemic
2.0
22.0
272
1456
R03AC02
ATC
salbutamol; inhalant
1.4
22.0
1658
13712
G02.0*A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
21.9
21
*
WX892
NOMESCO Finland
Monitored bed care
2.1
21.9
222
1108
183
Kela drug reimbursment
Lamotrigin and topiramate
4.9
21.8
48
100
J05AB01
ATC
aciclovir; systemic
1.6
21.5
657
4528
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
21.3
398
2421
J01MA02
ATC
ciprofloxacin; systemic
1.5
21.2
1067
8165
N05CF01
ATC
zopiclone; oral
1.5
21.1
886
6538
1380A
ICD-9 Finland
Late effects of acute poliomyelitis[SEQUELAE POLIOMYELITIDIS]
77.3
20.7
23
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
20.6
289
1613
N06AB04
ATC
citalopram; systemic
1.6
20.6
598
4070
N06AX11
ATC
mirtazapine; oral
1.5
20.3
1012
7712
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
20.3
786
5696
ZXD05
NOMESCO Finland
Urgent procedure
1.5
20.2
861
6361
A02BC05
ATC
esomeprazole; systemic
1.4
20.2
1146
8949
WX730
NOMESCO Finland
Conventional respirator
4.0
20.1
57
145
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
20.0
420
2638
0479X
ICD-9 Finland
Meningitis due to enterovirus, Unspecified viral meningitis
+∞
19.8
19
*
N02BE01
ATC
paracetamol; systemic, rectal
1.6
19.7
2685
24653
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
19.7
364
2205
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
19.7
1626
13561
N06AX21
ATC
duloxetine; oral
1.7
19.6
375
2294
J01FF01
ATC
clindamycin; systemic
1.5
19.4
768
5586
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
18.9
441
2844
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
15.9
18.8
30
19
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
+∞
18.8
18
*
J01MA12
ATC
levofloxacin; systemic
1.6
18.7
493
3275
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.5
18.7
64
186
N05AH04
ATC
quetiapine; oral
1.6
18.5
548
3739
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
18.0
110
443
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
17.9
183
915
J01FA06
ATC
roxithromycin; oral
1.4
17.8
1115
8811
G05.1*A85.0
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis (in) enteroviral
+∞
17.7
17
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
17.4
310
1857
N06AB10
ATC
escitalopram; oral
1.5
17.4
634
4519
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.7
17.3
39
83
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
17.3
311
1869
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.6
17.2
56
157
N05BA09
ATC
clobazam; oral
5.2
17.2
35
68
H02AB09
ATC
hydrocortisone; systemic
2.8
17.2
86
313
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
17.0
571
3999
J02AC01
ATC
fluconazole; systemic
1.4
17.0
1120
8912
J01DA01
ATC
[U] cefalexin
1.4
16.9
1778
15267
N02AA05
ATC
oxycodone; systemic
1.6
16.8
462
3094
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
16.5
206
1107
M54.5
ICD-10 Finland
Low back pain
1.4
16.4
1093
8701
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
15.4
16.2
26
17
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
16.1
208
1129
A02BC01
ATC
omeprazole; systemic
1.5
16.1
721
5341
N06AX16
ATC
venlafaxine; oral
1.6
16.1
437
2916
N03AB02
ATC
phenytoin; systemic
4.2
16.0
42
101
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
5.1
16.0
33
65
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
15.7
200
1082
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
15.7
310
1911
J01FA10
ATC
azithromycin; systemic
1.4
15.7
1708
14671
04500
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Coxsackie virus
+∞
15.6
15
*
04301, ,
ICD-8 Finland
+∞
15.6
15
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
15.6
653
4774
R55
ICD-10 Finland
Syncope and collapse
1.7
15.5
288
1746
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
15.4
161
812
A02BC03
ATC
lansoprazole; oral
1.4
15.4
746
5602
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
15.3
436
2938
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
15.3
271
1620
L28
ICPC
Limited function/disability (L)
1.5
15.3
487
3366
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
16.1
15.2
24
15
M01AB05
ATC
diclofenac; systemic, rectal
1.4
15.2
1890
16531
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
15.2
232
1328
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
15.2
170
880
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
15.1
706
5266
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.9
15.1
68
234
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.1
15.0
61
198
N99
ICPC
Neurological disease other
3.6
14.9
48
134
N03AE01
ATC
clonazepam; systemic
2.0
14.8
163
838
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
14.8
598
4336
H02AB07
ATC
prednisone; oral
1.6
14.7
356
2311
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.1
14.6
146
725
B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
14.6
14
*
Z3231
NOMESCO Finland
Registered nurse
1.4
14.6
728
5490
M01AE02
ATC
naproxen; oral, rectal
1.3
14.6
1638
14066
S06.0
ICD-10 Finland
Concussion
1.6
14.6
318
2010
SPAT1254
SPAT
Administration of medicine
1.6
14.5
390
2592
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
14.5
121
560
PA2AD
NOMESCO Finland
CT angiography of brain
4.2
14.4
38
92
JN4BD
NOMESCO Finland
Extensive body CT
1.7
14.4
253
1510
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
14.3
228
1323
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
14.1
201
1127
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.2
14.0
112
510
N29
ICPC
Neurological sympt/complt other
2.9
13.9
66
234
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
13.8
748
5714
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
13.6
841
6564
R4110
NOMESCO Finland
Physiotherapy
1.4
13.6
742
5673
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
75.5
13.6
15
*
04699
ICD-8 Finland
Other enterovirus diseases of central nervous system
+∞
13.5
13
*
G02.0
ICD-10 Finland
Meningitis in viral diseases classified elsewhere
+∞
13.5
13
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
13.5
482
3406
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.8
13.4
40
106
120
Kela drug reimbursment
Hypogammaglobulinaemia
12.9
13.4
23
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
13.4
847
6636
G04.8
ICD-10 Finland
Other encephalitis, myelitis and encephalomyelitis
25.8
13.4
18
7
N70
ICPC
Poliomyelitis
21.2
13.3
19
9
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
13.3
400
2725
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
13.0
255
1566
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.0
13.0
137
694
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.4
13.0
46
137
3229X
ICD-9 Finland
Meningitis of unspecified cause, Meningitis, unspecified
28.5
12.9
17
6
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
12.8
256
1582
Z3226
NOMESCO Finland
Physiotherapist
1.5
12.7
475
3385
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
12.7
672
5105
G02.0*B02.1
ICD-10 Finland
Zoster meningitis
+∞
12.5
12
*
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
12.5
12
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
12.5
1122
9253
N03AX09
ATC
lamotrigine; oral
1.9
12.5
159
861
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
12.4
177
994
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
12.3
510
3704
C03CA01
ATC
furosemide; systemic
1.4
12.3
669
5102
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
12.3
765
5966
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
5.8
12.3
22
38
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
12.2
210
1244
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.7
12.2
38
104
J01FA09
ATC
clarithromycin; systemic
1.4
12.2
863
6864
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
12.1
366
2494
UJF32
NOMESCO Finland
Coloscopy
1.4
12.1
648
4927
A03
ICPC
Fever
1.4
12.1
520
3804
J01CA04
ATC
amoxicillin; systemic
1.4
12.1
2448
22612
J01EA01
ATC
trimethoprim; systemic
1.4
12.0
670
5126
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
12.0
486
3513
N05CD07
ATC
temazepam; oral
1.6
12.0
268
1703
A69.2
ICD-10 Finland
Lyme disease
1.8
12.0
175
989
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
11.9
521
3819
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.3
11.9
92
413
F05.8
ICD-10 Finland
Other delirium
4.4
11.9
29
66
A88.1
ICD-10 Finland
Epidemic vertigo
46.8
11.9
14
*
C01CA24
ATC
epinephrine; parenteral
1.8
11.9
196
1149
N02BF01
ATC
gabapentin; oral
1.6
11.8
293
1908
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
11.8
131
677
N03AX11
ATC
topiramate; oral
2.4
11.8
80
340
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
11.6
191
1118
A06AD11
ATC
lactulose; oral
1.5
11.6
345
2342
N02BF02
ATC
pregabalin; oral
1.7
11.5
198
1174
N02AC04
ATC
dextropropoxyphene; oral
2.3
11.5
85
375
G03.2
ICD-10 Finland
Benign recurrent meningitis [Mollaret]
120.4
11.4
12
*
J01DA09
ATC
[U] cefadroxil
1.4
11.4
712
5545
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.2
11.4
91
415
N05CF02
ATC
zolpidem; oral
1.4
11.4
473
3435
R47.0
ICD-10 Finland
Dysphasia and aphasia
3.6
11.3
36
100
N30.0
ICD-10 Finland
Acute cystitis
1.4
11.3
463
3354
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.5
11.2
68
274
N28
ICPC
Limited function/disability (N)
2.8
11.2
54
194
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
11.2
199
1192
ZXE00
NOMESCO Finland
One hour or less
1.3
11.2
1033
8523
B02.0
ICD-10 Finland
Zoster encephalitis
20.1
11.1
16
8
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
20.1
11.1
16
8
R06.0
ICD-10 Finland
Dyspnoea
1.4
11.1
702
5474
UKC02
NOMESCO Finland
Cystoscopy
1.5
11.1
350
2405
H02AB04
ATC
methylprednisolone; systemic
1.5
11.0
364
2527
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.9
11.0
129
680
R01AD09
ATC
mometasone; nasal
1.3
11.0
1299
11071
A28
ICPC
Limited function/disability NOS
1.5
11.0
411
2925
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
13.9
11.0
18
13
G03.8
ICD-10 Finland
Meningitis due to other specified causes
43.5
10.9
13
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.1
10.9
104
509
R06AE07
ATC
cetirizine; oral
1.3
10.9
1257
10677
A46
ICD-10 Finland
Erysipelas
1.5
10.8
357
2476
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
10.8
397
2816
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.4
10.7
74
317
L01BA01
ATC
methotrexate; systemic
2.1
10.7
98
472
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
10.7
510
3793
G41.0
ICD-10 Finland
Grand mal status epilepticus
12.9
10.6
18
14
A84
ICD-10 Finland
Tick-borne viral encephalitis
60.2
10.6
12
*
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.2
10.6
91
428
R07.3
ICD-10 Finland
Other chest pain
1.6
10.5
285
1894
W19
ICD-10 Finland
Unspecified fall
1.6
10.5
265
1734
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
10.5
276
1824
C07AB07
ATC
bisoprolol; oral
1.3
10.4
1172
9902
R52.1
ICD-10 Finland
Chronic intractable pain
3.4
10.4
36
106
Z2221
NOMESCO Finland
Medical doctor
1.3
10.3
727
5755
N17
ICPC
Vertigo/dizziness
1.5
10.3
331
2284
7840A
ICD-9 Finland
Symptoms involving head and neck, Headache
3.5
10.3
35
102
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
10.3
769
6144
G44.8
ICD-10 Finland
Other specified headache syndromes
2.6
10.2
56
215
A02BA02
ATC
ranitidine; systemic
1.4
10.2
450
3300
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.7
10.2
168
985
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
10.2
289
1942
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
10.1
222
1404
N05AX08
ATC
risperidone; systemic
1.6
10.1
225
1428
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.7
10.1
181
1086
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
10.1
327
2261
M01AX17
ATC
nimesulide; oral
1.4
10.1
565
4317
G43.3
ICD-10 Finland
Complicated migraine
2.5
10.0
61
247
D09
ICPC
Nausea
1.8
10.0
139
775
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.0
9.9
106
542
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
9.9
835
6782
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
9.8
249
1630
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.7
9.8
50
185
N05BA12
ATC
alprazolam; oral
1.6
9.8
260
1722
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.0
9.8
43
147
R25.2
ICD-10 Finland
Cramp and spasm
2.3
9.7
70
306
ZXY02
NOMESCO Finland
Neuropsychologist
4.1
9.7
26
64
WX704
NOMESCO Finland
Intubation
1.6
9.7
212
1341
A07AA02
ATC
nystatin; oral
1.8
9.6
140
791
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.5
9.6
32
92
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.9
9.6
113
597
SPAT1255
SPAT
Intravenous administration of medicine
1.7
9.6
167
995
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
9.6
524
3985
M79.6
ICD-10 Finland
Pain in limb
1.3
9.6
1224
10481
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.6
9.5
227
1468
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
100.3
9.4
10
*
0632A
ICD-9 Finland
Tick-borne viral encephalitis, Central European encephalitis[PUUTIAISEN VÄLITTÄMÄ ENKEFALIITTI (KUMLINGE)]
+∞
9.4
9
*
G03.1
ICD-10 Finland
Chronic meningitis
+∞
9.4
9
*
G03.0
ICD-10 Finland
Nonpyogenic meningitis
+∞
9.4
9
*
J01MA14
ATC
moxifloxacin; systemic
1.6
9.3
225
1456
ZXA10
NOMESCO Finland
Bilateral
1.4
9.2
441
3276
R02
ICPC
Shortness of breath/dyspnoea
1.5
9.2
344
2443
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.1
9.2
38
125
B01AA03
ATC
warfarin; systemic
1.4
9.2
384
2784
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
9.2
894
7386
5CM18, ,
NOMESCO Finland
7.7
9.1
20
26
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
9.1
282
1930
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
9.1
131
739
PA6AD
NOMESCO Finland
CT of neck arteries
2.0
9.1
102
531
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
11.5
9.1
16
14
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
1.8
9.0
125
696
G40
ICD-10 Finland
Epilepsy
3.3
9.0
33
101
Z2446
NOMESCO Finland
Social worker
1.7
9.0
181
1121
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.0
1138
9713
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
9.0
650
5156
SPAT1263
SPAT
Sampling
1.3
8.9
1104
9390
6BA02, ,
NOMESCO Finland
7.4
8.9
20
27
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.0
8.9
93
472
SPAT1301
SPAT
No procedures
1.3
8.9
777
6327
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.0
8.8
24
60
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
8.8
2092
19202
R03DC03
ATC
montelukast; oral
1.4
8.7
448
3370
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
8.7
146
862
SPAT1229
SPAT
Assessment of need for aid
1.7
8.7
170
1046
A04
ICPC
Weakness/tiredness general
1.4
8.7
427
3188
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.5
8.6
51
204
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
8.6
354
2562
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.8
8.5
129
739
G81.9
ICD-10 Finland
Hemiplegia, unspecified
3.2
8.5
33
105
F43.21
ICD-10 Finland
Adaptation disorder with prolonged depression
3.2
8.5
33
105
N73
ICPC
Neurological infection other
27.6
8.5
11
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.8
8.5
119
667
PA7BD
NOMESCO Finland
CT angiography of neck and brain
2.8
8.4
42
154
L04AA13
ATC
[U] leflunomide
2.2
8.4
65
294
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
8.4
705
5702
A81.9
ICD-10 Finland
Atypical virus infection of central nervous system, unspecified
+∞
8.3
8
*
A81.8
ICD-10 Finland
Other atypical virus infections of central nervous system
+∞
8.3
8
*
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.3
8.3
59
257
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
8.3
145
866
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
8.3
418
3134
B01AB05
ATC
enoxaparin; parenteral
1.3
8.3
757
6192
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.2
493
3799
M79.7
ICD-10 Finland
Fibromyalgia
1.9
8.2
98
522
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.6
8.1
163
1009
R96
ICPC
Asthma
1.5
8.1
252
1726
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
2.3
8.1
59
260
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.5
8.1
27
78
P01BA02
ATC
hydroxychloroquine; oral
1.6
8.1
201
1312
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
8.1
350
2556
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.7
8.1
154
942
WW200
NOMESCO Finland
Immunization
2.1
8.0
74
359
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
8.0
240
1631
T78.4
ICD-10 Finland
Allergy, unspecified
1.8
8.0
127
738
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.8
8.0
112
627
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
2.6
8.0
45
176
J01CA08
ATC
pivmecillinam; oral
1.3
8.0
1076
9216
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
2.9
8.0
35
120
D06BB03
ATC
aciclovir; topical
1.8
8.0
114
643
J20
ICD-10 Finland
Acute bronchitis
1.5
7.9
277
1942
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.2
7.9
65
301
R03BA02
ATC
budesonide; inhalant
1.4
7.9
470
3612
L04AA06
ATC
mycophenolic acid; systemic
2.4
7.9
53
225
R10.0
ICD-10 Finland
Acute abdomen
2.0
7.9
88
457
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.7
7.9
135
802
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.6
7.9
42
160
W17
ICD-10 Finland
Other fall from one level to another
1.8
7.8
109
609
A02BA04
ATC
nizatidine; systemic
1.6
7.8
164
1027
G93.4
ICD-10 Finland
Encephalopathy, unspecified
8.5
7.8
16
19
X58
ICD-10 Finland
Exposure to other specified factors
1.4
7.8
411
3101
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
1.8
7.8
118
677
N89
ICPC
Migraine
1.8
7.8
110
618
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.8
7.8
103
567
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.7
7.8
125
730
G51.0
ICD-10 Finland
Bell palsy
2.1
7.7
71
344
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
7.7
573
4551
B02.1
ICD-10 Finland
Zoster meningitis
45.1
7.7
9
*
EB1VA, ,
NOMESCO Finland
1.3
7.7
484
3752
A04AA01
ATC
ondansetron; systemic, rectal
1.6
7.7
197
1296
WX882
NOMESCO Finland
High dependency care
2.1
7.6
70
339
A01
ICPC
Pain general/multiple sites
1.5
7.6
267
1873
EMB10
NOMESCO Finland
Tonsillectomy
1.6
7.6
163
1026
M02AA07
ATC
piroxicam; topical
1.3
7.6
855
7161
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.0
7.6
79
401
64090
ICD-8 Finland
Artificial termination of pregnancy performed for medical reasons, Woman's illness or physical defect (medicines. Cause)
3.2
7.5
29
92
C07AB02
ATC
metoprolol; systemic
1.4
7.5
422
3216
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
7.5
565
4497
L04AX03
ATC
methotrexate; systemic
1.5
7.5
246
1706
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.7
7.4
144
885
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.5
7.4
233
1600
A87.2
ICD-10 Finland
Lymphocytic choriomeningitis
80.3
7.4
8
*
G05.1*B02.0
ICD-10 Finland
Zoster encephalitis
80.3
7.4
8
*
H53.2
ICD-10 Finland
Diplopia
1.9
7.4
85
447
N06AB03
ATC
fluoxetine; oral
1.4
7.4
308
2233
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.6
7.4
181
1178
32088
ICD-8 Finland
Meningitis, Alia definita
13.4
7.4
12
9
N06AA10
ATC
nortriptyline; systemic
2.2
7.3
58
265
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
7.3
100
556
C08DA01
ATC
verapamil; systemic
1.8
7.3
100
557
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.7
7.3
134
812
M01AH05
ATC
etoricoxib; oral
1.2
7.3
1733
15728
N06AB06
ATC
sertraline; oral
1.4
7.3
310
2256
M25.5
ICD-10 Finland
Pain in joint
1.3
7.3
909
7703
S22.3
ICD-10 Finland
Fracture of rib
1.6
7.2
180
1175
M54.2
ICD-10 Finland
Cervicalgia
1.5
7.2
218
1484
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.8
7.2
99
551
R40.2
ICD-10 Finland
Coma, unspecified
3.4
7.2
25
74
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
6.2
7.2
18
29
R03BA08
ATC
ciclesonide; inhalant
1.5
7.2
224
1535
N18
ICPC
Paralysis/weakness
2.4
7.2
49
210
S20.2
ICD-10 Finland
Contusion of thorax
1.7
7.2
136
830
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
7.2
272
1937
R60.0
ICD-10 Finland
Localized oedema
1.4
7.2
294
2124
SPAT1216
SPAT
Assessment of functional ability
1.4
7.2
341
2528
C08CA01
ATC
amlodipine; oral
1.3
7.2
876
7400
S80.0
ICD-10 Finland
Contusion of knee
1.5
7.2
208
1406
N05AA02
ATC
levomepromazine; systemic
1.8
7.1
100
561
M54.1
ICD-10 Finland
Radiculopathy
1.8
7.1
105
598
R29.1
ICD-10 Finland
Meningismus
20.1
7.1
10
5
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.1
7.1
68
335
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
7.1
39
151
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.0
7.1
75
384
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
1.9
7.1
79
412
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
6.0
7.1
18
30
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.5
7.1
231
1600
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
7.0
247
1734
I95.1
ICD-10 Finland
Orthostatic hypotension
1.9
7.0
85
455
R03BA05
ATC
fluticasone; inhalant
1.3
7.0
464
3621
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
7.0
207
1404
M01AB55
ATC
diclofenac, combinations; oral
1.6
7.0
143
891
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.0
641
5231
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.2
7.0
58
271
R05
ICPC
Cough
1.3
6.9
655
5364
P06
ICPC
Sleep disturbance
1.4
6.9
353
2648
R03BA01
ATC
beclometasone; inhalant
1.4
6.9
340
2535
A01AB09
ATC
miconazole; local oral
1.5
6.9
198
1334
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.5
6.9
181
1196
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.9
6.9
84
451
SPAT1262
SPAT
Handing over of treatment supplies
1.4
6.9
386
2939
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
1.9
6.9
79
416
M70.6
ICD-10 Finland
Trochanteric bursitis
1.4
6.9
319
2356
NG4AA
NOMESCO Finland
Lower leg X-ray examination
1.9
6.9
84
452
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
6.9
49
215
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.5
6.8
42
172
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
2.3
6.8
48
209
M01AH02
ATC
rofecoxib; oral
1.4
6.8
271
1948
R01AD08
ATC
fluticasone; nasal
1.3
6.8
761
6361
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.8
529
4226
G04.0
ICD-10 Finland
Acute disseminated encephalitis
40.1
6.8
8
*
J45.8
ICD-10 Finland
Mixed asthma
1.9
6.7
74
384
D06
ICPC
Abdominal pain localized other
1.5
6.7
230
1607
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.7
1276
11283
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
6.7
249
1768
ZXD35
NOMESCO Finland
Usual procedure
1.9
6.7
80
427
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.1
6.7
60
289
N02CX04, ,
ATC
2.3
6.7
48
211
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.7
6.7
113
671
L04AX01
ATC
azathioprine; systemic
1.7
6.6
105
611
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.6
6.6
158
1022
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.6
1698
15458
J46
ICD-10 Finland
Status asthmaticus
1.9
6.6
73
379
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.5
6.6
209
1438
L29
ICPC
Musculoskeletal sympt/complt other
1.5
6.6
222
1546
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.7
6.6
128
788
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.9
6.6
82
444
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
6.6
206
1415
R60.1
ICD-10 Finland
Generalized oedema
3.2
6.6
25
79
D11
ICPC
Diarrhoea
1.4
6.5
328
2456
N05BA06
ATC
lorazepam; systemic, sublingual
1.7
6.5
120
729
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
6.5
112
669
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
6.5
2680
25658
A88.0
ICD-10 Finland
Enteroviral exanthematous fever [Boston exanthem]
70.0
6.4
7
*
J01MA06
ATC
norfloxacin; oral
1.4
6.4
298
2202
R5110, ,
SPAT
1.5
6.4
195
1332
N05AB04
ATC
prochlorperazine; systemic, rectal
2.2
6.4
49
222
R81
ICPC
Pneumonia
1.8
6.4
90
507
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
6.4
334
2517
J35.0
ICD-10 Finland
Chronic tonsillitis
1.6
6.4
145
929
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.4
571
4642
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
6.4
137
866
A10AC01
ATC
insulin (human); parenteral
1.5
6.3
176
1180
G41.2
ICD-10 Finland
Complex partial status epilepticus
9.3
6.3
12
13
R35
ICD-10 Finland
Polyuria
1.6
6.3
150
972
0451X
ICD-9 Finland
Acute poliomyelitis with other paralysis[POLIOMYEL ACUTA CUM PARALYSI SPINALI/ALIA, NUD]
+∞
6.3
6
*
0459X
ICD-9 Finland
Acute poliomyelitis, unspecified[POLIOMYELITIS ACUTA NUD,NUD]
+∞
6.3
6
*
F02.19*A81.0
ICD-10 Finland
Dementia in Jakob-Creutzfeldt's disease without information on additional symptoms
+∞
6.3
6
*
R33
ICD-10 Finland
Retention of urine
1.6
6.2
154
1005
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.2
96
555
G01AF05
ATC
econazole; vaginal
1.5
6.2
173
1159
A87
ICD-10 Finland
Viral meningitis
26.7
6.2
8
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
26.7
6.2
8
*
C05AA08
ATC
fluocortolone; rectal, topical
1.4
6.2
306
2282
E000002, ,
ATC
1.4
6.2
270
1972
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
2.4
6.2
39
162
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.0
6.2
63
319
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
6.2
1522
13767
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
3.1
6.2
24
77
R06.4
ICD-10 Finland
Hyperventilation
2.3
6.2
42
181
C03DA01
ATC
spironolactone; oral
1.4
6.1
263
1916
RD210, ,
NOMESCO Finland
2.2
6.1
47
213
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.1
297
2210
JN4AD
NOMESCO Finland
Body CT examination
1.4
6.1
248
1790
J01.1
ICD-10 Finland
Acute frontal sinusitis
2.2
6.1
50
233
A01AB04
ATC
amphotericin B; local oral
1.7
6.1
98
574
SPAT1104
SPAT
Monitoring of emergency patient
1.6
6.1
144
931
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
6.1
700
5858
M02AA10
ATC
ketoprofen; topical
1.3
6.1
370
2852
G40.89
ICD-10 Finland
Other epilepsy
4.1
6.1
16
39
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
3.0
6.1
25
83
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
6.1
189
1298
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.8
6.1
80
442
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.4
6.0
286
2120
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
6.0
628
5195
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
6.0
969
8403
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.6
6.0
133
846
TPH04, ,
SPAT
2.7
6.0
30
111
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.2
6.0
49
228

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
534
654
9.64
307.65
1.5
1.4
70.79
38.94
e6/l
1.38
419
472
636
745
10.46
307.65
1.5
1.3
688.38
531.46
mg/l
7.30
613
711
369
330
12.55
307.65
1.4
1.5
—
—
—
0
0
462
252
21.34
307.65
1.3
1.6
—
—
—
0
0
538
665
9.57
307.65
1.5
1.5
557.29
1420.62
e6/l
0.94
433
511
620
663
11.42
307.65
1.4
1.3
3.61
3.72
mmol/l
1.08
588
625
553
612
10.76
307.65
1.5
1.4
—
—
—
0
0
317
293
11.93
300.49
1.1
1.1
—
—
—
0
0
259
216
12.98
261.68
1.4
1.3
2.22
1.98
mmol/l
2.76
247
200
287
313
10.00
241.41
1.6
1.7
—
—
—
0
0
180
112
16.99
213.90
1.2
1.1
98.20
265.70
ng/l
0.80
86
30
603
1959
3.58
152.89
2.7
2.4
20.66
21.86
au/ml
0.12
53
238
563
1806
3.58
145.05
1.5
1.3
47.65
51.36
au/ml
0.16
33
128
1231
6959
2.27
100.90
5.0
4.3
—
—
—
0
0
119
137
8.99
95.18
1.4
1.3
85.54
58.46
%
2.13
50
13
119
176
6.99
76.88
1.2
1.2
—
—
—
0
0
80
84
9.75
68.50
1.5
1.2
12.70
25.50
%
—
40
6
197
545
3.79
61.59
2.2
3.0
28.79
34.83
umol/l
3.01
171
493
1218
7984
1.86
57.90
2.8
2.2
202.34
212.98
u/l
0.13
1170
7599
465
2185
2.33
55.00
4.0
2.9
10.03
10.66
g/l
2.67
432
2011
47
30
15.89
54.65
1.2
1.2
64.51
41.10
%
—
41
10
124
272
4.71
52.68
1.1
1.1
—
—
—
0
0
696
3939
1.99
50.52
2.4
2.2
29.52
29.51
s
0.02
678
3823
1713
12924
1.72
46.86
8.4
6.6
2.65
2.81
%
2.27
1622
12184
1716
12954
1.72
46.83
8.5
6.7
8.67
8.71
%
0.28
1627
12225
1563
11508
1.72
46.69
14.7
13.7
1.20
1.22
inr
0.70
1317
9541
114
258
4.55
46.59
1.4
1.1
52.80
40.69
mg/l
1.44
95
211
1709
12917
1.71
46.15
8.6
6.7
0.67
0.68
%
0.63
1621
12167
1805
13878
1.71
45.47
6.9
6.4
10.50
11.31
umol/l
1.75
1722
13252
112
256
4.50
45.21
2.8
2.2
1358.54
1300.93
e6/l
0.26
96
226
1970
15540
1.72
44.90
6.1
5.1
6.69
6.60
mmol/l
0.92
1876
14672
1715
13093
1.69
43.54
8.1
6.5
56.84
56.94
%
0.13
1646
12574
1735
13326
1.68
42.69
8.4
6.6
28.37
28.34
%
0.04
1663
12697
90
180
5.12
42.62
2.4
2.4
570.34
568.50
e6/l
0.01
70
147
106
245
4.44
42.19
1.3
1.1
322.90
260.96
mg/l
1.59
91
211
90
183
5.03
41.82
2.7
2.5
225.03
218.12
e6/l
0.11
73
156
1813
14151
1.67
41.34
7.9
6.5
0.04
0.04
e9/l
0.71
1605
12247
1808
14138
1.66
40.60
8.0
6.5
0.58
0.57
e9/l
1.35
1598
12241
1687
12979
1.65
40.22
8.5
7.2
1.21
1.21
mmol/l
0.49
1469
11263
1542
11598
1.65
40.20
7.7
6.6
1.21
1.21
mmol/l
0.87
1432
10782
2132
17434
1.70
40.04
5.9
4.6
1980.96
1860.15
e6/l
0.02
28
229
58
80
7.37
39.86
1.3
1.3
—
—
—
0
0
1850
14601
1.66
39.61
8.1
6.7
0.18
0.19
e9/l
1.57
1658
12854
1334
9724
1.65
38.96
4.4
3.6
27.55
47.75
ng/l
1.75
879
6279
1831
14462
1.64
38.64
8.1
6.5
1.96
1.94
e9/l
0.15
1660
12825
89
199
4.57
36.94
1.4
1.2
0.57
0.60
ratio
0.30
55
112
88
206
4.37
34.48
2.6
2.0
74.53
74.10
%
0.10
88
200
1927
15747
1.58
32.48
11.0
9.6
4.20
4.07
e9/l
1.63
1716
13718
335
1703
2.08
31.69
2.3
1.9
1.21
1.35
g/l
0.90
308
1584
1159
8470
1.59
31.56
3.0
2.6
55.63
69.41
u/l
0.83
1080
7887
129
441
3.01
28.71
1.2
1.2
—
—
—
0
0
2346
20353
1.61
28.26
10.0
8.1
76.33
78.01
u/l
1.29
2247
19401
1482
11724
1.50
26.64
6.0
5.1
35.59
36.08
g/l
2.73
1398
11043
198
872
2.36
26.59
2.7
1.8
0.22
0.23
g/l
0.59
184
826
71
173
4.18
26.45
1.2
1.1
1576.38
1494.39
miu/ml
0.23
71
173
458
2739
1.79
26.36
2.5
2.2
357.71
380.84
nmol/l
1.85
431
2541
55
110
5.07
26.10
2.0
2.3
11.27
9.18
%
0.79
55
105
201
900
2.32
25.99
2.7
1.7
1.14
1.20
g/l
1.74
191
853
843
5931
1.58
25.95
3.1
2.7
4.75
6.27
e6/l
4.34
768
5400
1141
8585
1.52
25.88
4.1
3.3
105.08
64.32
e6/l
0.37
900
6514
1003
7422
1.52
24.24
3.9
3.2
0.28
0.38
e6/l
1.72
763
5407
40
64
6.32
23.99
1.4
1.0
—
—
—
0
0
934
6825
1.53
23.87
4.6
4.2
91.97
91.28
%
0.40
913
6676
45
82
5.55
23.66
1.8
2.2
0.27
0.21
e9/l
0.39
23
39
28
30
9.41
23.53
1.6
3.1
—
—
—
0
0
2268
19872
1.52
22.76
5.7
4.3
11.72
11.12
mm/h
1.22
2162
18722
348
2009
1.82
22.34
2.7
2.7
65.47
66.71
g/l
2.08
316
1863
30
39
7.76
21.68
1.1
1.1
—
—
—
0
0
641
4400
1.57
21.37
4.0
3.5
0.82
0.82
mmol/l
0.39
601
4161
1266
9999
1.45
21.31
4.8
3.9
38.43
96.93
e6/l
5.56
937
6924
1033
7859
1.47
21.11
3.5
3.1
—
—
—
0
0
27
8
34.03
21.11
1.1
1.0
—
—
—
0
0
716
5064
1.54
20.82
3.2
2.9
519.05
530.28
mosm/kgh2o
0.67
629
4443
847
6250
1.49
19.98
2.0
1.9
0.93
1.12
mg/l
1.34
618
4746
520
3457
1.60
19.71
7.5
6.1
1.02
1.05
mmol/l
1.49
490
3221
937
7079
1.46
19.52
3.3
3.2
968.78
1216.22
ng/l
2.13
777
5993
86
292
3.00
19.44
1.4
1.4
2.54
3.01
g/l
1.54
61
204
86
292
3.00
19.44
1.4
1.4
0.32
0.39
g/l
1.20
61
202
86
293
2.99
19.33
1.4
1.4
5.73
6.66
g/l
2.11
62
206
600
4145
1.55
19.22
2.9
2.5
2.37
2.35
g/l
0.31
552
3854
456
2957
1.63
19.09
7.5
8.5
7.43
7.42
ph
2.97
261
1602
85
291
2.97
18.95
1.5
1.4
—
—
—
0
0
848
6330
1.47
18.64
2.2
2.0
—
—
—
0
0
450
2942
1.62
18.17
7.5
8.4
1.03
0.92
mmol/l
0.24
382
2419
452
2959
1.62
18.15
7.5
8.5
5.04
5.10
kpa
0.61
435
2854
1395
11437
1.40
18.03
2.3
2.1
97.63
96.90
pmol/l
0.23
779
6161
584
4064
1.54
17.98
1.8
1.7
1139.40
1175.13
nmol/l
0.42
455
3109
451
2960
1.61
17.91
7.5
8.5
11.97
12.59
kpa
1.59
432
2854
409
2625
1.64
17.77
3.9
3.8
5.83
5.83
kpa
0.03
397
2558
408
2633
1.63
17.32
3.9
3.9
7.38
7.38
ph
0.01
239
1501
691
5021
1.48
17.21
4.0
3.7
262.44
448.35
ng/l
1.07
487
3648
547
3805
1.53
16.77
3.0
2.6
22.90
23.16
%
0.16
504
3555
939
7260
1.42
16.73
1.8
1.7
20.03
20.20
nmol/l
0.14
803
6241
275
1612
1.77
16.65
4.6
3.7
7.42
7.41
ph
0.26
236
1336
623
4469
1.49
16.46
2.9
2.6
13.06
13.50
umol/l
0.73
580
4182
637
4591
1.49
16.44
3.3
2.9
1.27
1.16
e6/l
0.24
326
2391
532
3693
1.53
16.44
1.8
1.6
—
—
—
0
0
186
967
1.98
16.38
2.0
2.0
3.60
1.73
ug/l
0.34
159
860
1001
7865
1.40
16.13
4.9
4.2
7.40
7.40
ph
1.33
724
5614
279
1658
1.75
16.10
4.6
3.6
5.20
5.16
kpa
0.33
265
1600
794
6001
1.43
15.91
1.8
1.5
2.28
2.35
g/l
0.42
522
3837
122
545
2.29
15.90
1.2
1.1
16.79
16.21
au/ml
0.02
13
149
391
2548
1.61
15.89
4.0
3.9
1.91
1.81
mmol/l
0.24
349
2212
130
597
2.23
15.87
1.4
1.4
—
—
—
0
0
176
910
1.99
15.74
2.4
2.4
641.98
403.32
ug/l
0.59
167
869
153
755
2.08
15.56
2.1
2.2
10.80
11.40
mg/l
0.39
137
706
52
151
3.48
15.23
1.5
1.5
12.48
13.29
u/l
0.27
52
143
26
20
13.10
15.16
1.3
1.3
1.73
1.33
iu/ml
—
16
7
265
1580
1.74
15.10
3.8
4.1
24.43
24.24
mmol/l
0.53
260
1566
2160
19315
1.38
15.02
3.9
3.3
47.46
45.23
u/l
0.65
2057
18392
539
3818
1.50
15.01
2.2
2.1
—
—
—
0
0
112
497
2.30
14.85
1.5
1.7
0.50
0.77
g/l
3.01
81
388
370
2427
1.59
14.58
7.7
8.2
1.33
1.33
mmol/l
0.00
359
2379
1388
11662
1.34
14.13
3.9
3.4
6.22
6.22
ph
0.01
796
6678
341
2210
1.61
14.11
3.7
3.2
4.74
4.61
kpa
0.49
330
2150
1677
14500
1.34
14.00
4.5
3.8
6.97
5.56
estimate
0.10
375
3073
1683
14574
1.34
13.83
4.6
3.8
0.00
0.11
estimate
0.56
354
2892
564
4093
1.46
13.81
1.4
1.4
594.05
492.89
titre
0.62
121
850
1658
14343
1.33
13.63
4.6
3.8
0.00
0.00
estimate
0.50
369
3017
391
2640
1.55
13.55
7.9
8.9
95.41
95.80
%
0.54
378
2558
50
153
3.30
13.53
1.0
1.0
909.09
289.17
ng/l
1.20
34
109
882
6968
1.37
13.20
3.0
2.6
332.37
336.14
umol/l
0.52
794
6233
116
550
2.15
13.13
1.4
1.4
148.47
155.26
au/ml
0.22
29
153
463
3267
1.49
13.01
1.8
1.7
—
—
—
0
0
2815
26622
1.58
12.91
23.0
15.0
21.77
23.09
mg/l
1.48
2485
21786
91
394
2.35
12.81
1.8
1.9
19240.00
1913.33
titre
—
6
12
346
2303
1.56
12.75
9.6
8.0
8.28
9.19
mmol/l
2.06
327
2219
572
4220
1.44
12.73
3.5
3.0
3.22
2.59
e6/l
0.61
264
2012
127
633
2.05
12.62
1.2
1.3
280.67
256.85
u/ml
0.31
82
381
22
18
12.30
12.59
1.4
1.3
0.90
0.21
iu/ml
—
10
8
345
2302
1.56
12.57
5.0
4.0
7.36
7.35
ph
0.41
254
1688
365
2472
1.54
12.44
8.4
9.4
122.34
122.26
g/l
0.03
358
2421
48
152
3.19
12.32
1.0
1.0
779.13
738.70
ng/l
0.18
30
105
892
7129
1.35
12.22
2.5
2.3
2.82
2.75
mg/l
0.45
782
6191
1109
9160
1.33
12.13
3.6
3.4
2.34
2.35
mmol/l
3.04
1004
8411
1429
12236
1.31
12.03
14.4
11.0
0.00
0.00
e9/l
0.45
1179
9980
68
265
2.60
12.00
6.6
5.6
7.29
7.36
mmol/l
0.05
59
224
1144
9509
1.32
11.91
3.6
3.3
33.13
32.83
u/l
0.07
1088
9005
344
2323
1.54
11.86
8.8
9.5
—
—
—
0
0
671
5177
1.38
11.39
1.8
1.7
—
—
—
0
0
110
541
2.07
11.36
4.4
3.7
—
—
—
0
0
107
527
2.07
11.02
4.5
4.2
2.48
2.61
mmol/l
0.15
70
347
233
1464
1.64
10.90
8.7
11.4
16.43
16.08
%
1.08
224
1414
978
8029
1.32
10.89
3.8
3.2
0.81
0.15
estimate
0.37
311
2421
36
103
3.52
10.86
3.2
1.9
36.89
29.94
%
1.45
36
103
244
1556
1.62
10.76
9.1
10.7
24.32
24.31
mmol/l
0.01
235
1526
484
3565
1.42
10.73
1.8
1.8
—
—
—
0
0
1559
13633
1.29
10.69
3.6
3.2
113.23
111.10
ug/l
0.17
1453
12858
1448
12552
1.29
10.60
3.2
2.8
—
—
estimate
—
0
0
240
1530
1.62
10.60
7.1
7.0
25.25
24.43
mmol/l
2.80
231
1467
525
3931
1.40
10.59
2.6
2.6
191.85
122.09
ug/g
0.84
425
3179
2302
21210
1.32
10.45
4.9
4.5
14.71
14.67
pmol/l
0.35
2139
19722
189
1138
1.70
10.41
1.4
1.3
0.27
0.94
u/ml
—
6
87
335
2315
1.50
10.34
5.3
4.4
0.60
0.68
%
0.40
138
655
438
3193
1.43
10.26
2.5
2.8
8.28
7.38
umol/l
0.38
388
2786
150
854
1.79
10.06
3.5
2.8
24.65
24.68
mmol/l
0.04
145
844
158
914
1.77
10.04
4.7
3.9
25.26
24.79
mmol/l
1.51
145
849
123
659
1.90
10.00
3.9
3.0
—
—
—
0
0
1434
12476
1.28
9.97
2.9
2.5
76.33
76.15
nmol/l
0.09
1313
11464
179
1075
1.71
9.96
1.3
1.2
—
—
—
0
0
1281
10997
1.28
9.90
4.4
3.7
1.57
0.09
estimate
0.47
323
2516
470
3499
1.40
9.75
3.3
3.2
4.86
4.78
e9/l
0.05
405
3085
344
2422
1.47
9.66
5.5
4.5
0.79
0.93
%
0.51
134
689
90
439
2.08
9.56
4.5
5.9
344.55
369.89
umol/l
0.92
82
390
244
1602
1.57
9.52
1.3
1.2
—
—
—
0
0
394
2859
1.43
9.43
3.2
2.7
1.85
1.78
%
0.55
359
2572
358
2553
1.45
9.41
2.4
2.3
0.22
0.22
g/l
0.21
334
2395
100
513
1.98
9.26
1.1
1.1
—
—
—
0
0
114
612
1.90
9.24
4.5
3.3
57.53
57.90
%
0.11
114
612
980
8190
1.29
9.21
7.1
6.2
—
—
—
0
0
1036
8732
1.28
9.07
2.9
2.4
—
—
—
0
0
490
3727
1.37
8.89
1.3
1.2
—
—
—
0
0
111
599
1.88
8.87
2.7
2.2
128.72
130.21
g/l
0.24
79
475
173
1064
1.66
8.83
1.6
1.7
—
—
—
0
0
91
460
2.01
8.80
1.3
1.4
73.31
60.66
mmol/l
1.82
78
374
184
1153
1.63
8.74
4.9
3.8
—
—
—
0
0
16
16
10.04
8.52
1.0
1.0
—
—
—
0
0
414
3087
1.39
8.46
1.4
1.4
—
—
—
0
0
79
385
2.08
8.45
4.4
3.5
1.29
1.53
%
0.30
74
351
936
7847
1.28
8.43
4.8
3.9
0.00
0.00
estimate
1.94
346
2832
177
1110
1.63
8.39
1.7
1.9
1.48
1.51
g/l
0.16
149
979
324
2321
1.44
8.30
5.6
4.6
0.08
0.11
%
0.50
114
587
327
2349
1.44
8.25
5.8
4.8
0.06
0.25
%
0.69
114
552
44
169
2.63
8.10
2.9
2.8
39.20
44.30
%
1.07
29
86
305
2171
1.45
8.08
3.4
2.7
72.91
70.48
e9/l
0.53
220
1558
120
684
1.78
8.08
2.7
3.3
5.63
2.38
ratio
0.54
69
387
189
1219
1.59
7.99
3.2
1.9
8.25
6.90
iu/ml
0.27
51
290
364
2684
1.40
7.93
2.9
2.5
33.23
56.20
u/l
0.70
310
2299
799
6612
1.28
7.90
2.7
2.4
—
—
—
0
0
779
6431
1.28
7.84
4.4
3.9
1.02
1.25
kg/l
0.50
536
4256
835
6964
1.27
7.72
1.4
1.3
2.15
1.56
u/ml
0.38
213
1950
156
970
1.64
7.67
1.3
1.3
—
—
—
0
0
2778
26625
1.39
7.62
24.3
17.0
139.32
139.64
mmol/l
9.56
2746
26131
218
1470
1.52
7.57
3.3
2.2
—
—
—
0
0
790
6559
1.27
7.56
5.9
4.6
—
—
—
0
0
87
458
1.93
7.54
2.6
2.2
14.00
6.30
titre
—
5
10
339
2494
1.40
7.48
1.5
1.5
—
—
—
0
0
129
774
1.70
7.28
2.9
3.5
40.75
49.56
mg/l
0.32
104
670
172
1110
1.58
7.28
3.4
5.5
1.64
1.62
%
0.08
165
1048
230
1582
1.49
7.27
3.2
2.1
—
—
—
0
0
229
1576
1.49
7.22
3.2
2.2
—
—
—
0
0
92
502
1.86
7.17
1.0
1.1
—
—
—
0
0
230
1589
1.48
7.12
3.3
2.2
—
—
—
0
0
135
826
1.66
7.09
1.2
1.1
—
—
—
0
0
128
773
1.68
7.06
3.0
3.5
50.60
59.91
mg/l
0.35
103
668
65
319
2.06
6.89
2.1
2.7
—
—
—
0
0
188
1255
1.53
6.86
3.4
2.2
—
—
—
0
0
12
11
10.95
6.79
1.0
1.0
—
—
—
0
0
71
363
1.98
6.74
1.7
1.4
—
—
—
0
0
71
363
1.98
6.74
1.7
1.4
—
—
—
0
0
71
363
1.98
6.74
1.7
1.4
—
—
—
0
0
71
363
1.98
6.74
1.7
1.4
—
—
—
0
0
2777
26697
1.36
6.73
24.4
17.2
3.95
3.96
mmol/l
0.91
2741
26145
19
49
3.90
6.70
3.0
1.6
—
—
—
0
0
158
1021
1.58
6.67
3.9
5.7
0.86
0.88
%
0.41
152
964
143
903
1.61
6.65
4.3
3.5
1448.31
382.04
mg/l
0.49
70
407
224
1561
1.47
6.65
2.3
2.1
—
—
—
0
0
164
1070
1.56
6.64
1.9
2.3
20.40
20.82
s
0.65
144
952
50
226
2.23
6.54
1.0
1.1
—
—
—
0
0
380
2913
1.35
6.49
4.5
4.7
31.43
31.73
%
0.20
267
2016
130
807
1.64
6.48
1.4
1.4
281.78
292.59
ug/g
0.24
73
449
1209
10695
1.21
6.20
2.2
2.1
—
—
—
0
0
240
1719
1.43
6.17
10.6
10.5
93.86
94.05
%
0.19
240
1708
116
709
1.66
6.16
3.5
3.3
4.08
2.04
index
0.64
63
377
255
1848
1.41
6.14
3.0
3.5
4.40
4.55
pmol/l
1.84
229
1672
2593
24762
1.28
6.07
6.1
5.4
1.77
1.86
mu/l
3.32
2440
23224
186
1274
1.49
6.04
2.3
2.4
—
—
—
0
0
1025
8949
1.22
5.95
4.1
3.5
7.67
7.76
mmol/l
0.24
881
7706
121
757
1.62
5.88
3.9
6.6
1.28
1.28
mmol/l
0.01
103
665
166
1118
1.51
5.85
4.1
3.1
—
—
—
0
0
150
989
1.54
5.84
1.5
1.4
9.65
9.52
u/l
0.04
121
795
71
384
1.87
5.76
1.7
1.4
30.77
88.50
mu/l
1.32
63
342
922
7990
1.22
5.72
3.2
2.9
0.00
0.02
0.99
14
161
644
5377
1.25
5.68
1.7
1.7
47575064.36
29837005.72
pmol/l
0.27
536
4528
44
201
2.21
5.66
1.1
1.1
—
—
—
0
0
426
3385
1.30
5.63
1.6
1.5
—
—
—
0
0
602
4995
1.25
5.60
1.4
1.3
6.59
9.95
u/ml
0.99
229
2009
196
1378
1.45
5.59
4.0
3.0
0.65
0.62
%
1.02
196
1372
67
360
1.88
5.56
1.4
1.3
1810.28
368.45
pmol/l
0.46
58
311
163
1107
1.50
5.54
3.6
3.2
25.39
25.25
mmol/l
0.24
153
1069
614
5125
1.25
5.41
3.2
2.9
2.45
2.45
mmol/l
0.08
535
4613
49
239
2.07
5.36
4.8
3.9
—
—
—
0
0
128
832
1.56
5.33
1.2
1.3
46.67
91.57
titre
—
9
83
62
330
1.90
5.31
1.5
1.3
0.19
0.23
nmol/l
0.31
44
254
248
1838
1.38
5.26
3.1
3.2
184.00
185.08
ng/l
0.01
222
1673
180
1261
1.45
5.25
2.3
2.2
0.00
0.61
estimate
0.51
50
423
196
1398
1.43
5.20
4.2
3.0
1.35
1.28
%
0.33
196
1390
641
5402
1.23
5.15
1.4
1.3
30.91
28.32
iu/ml
0.21
195
1621
36
158
2.29
5.11
1.3
2.0
—
—
—
0
0
270
2045
1.35
5.01
6.7
3.8
1.22
1.23
mmol/l
0.91
236
1761
193
1383
1.42
5.00
2.9
2.4
2551.10
5714.46
u/l
2.09
68
546
70
396
1.79
4.97
1.5
1.3
0.14
0.37
nmol/l
—
7
19
124
815
1.54
4.94
1.2
1.3
890.00
1203.18
titre
—
5
22
115
744
1.57
4.92
1.5
1.3
9.74
6.64
iu/ml
—
5
13
275
2095
1.34
4.91
2.7
2.4
0.23
0.47
e6/l
2.54
261
1987
106
673
1.60
4.91
1.5
1.2
35.57
48.14
u/ml
0.37
13
71
128
849
1.53
4.90
2.2
2.4
9.58
10.36
g/l
1.00
113
765
308
2388
1.32
4.88
2.7
2.4
12.89
13.43
nmol/l
0.58
288
2201
264
2002
1.35
4.86
3.9
3.9
83.73
84.52
ng/l
0.05
226
1750
47
235
2.02
4.84
1.2
1.1
—
—
—
0
0
19
63
3.03
4.67
1.4
1.6
—
—
—
0
0
220
1633
1.37
4.65
4.1
3.3
126.55
130.67
g/l
1.92
215
1590
85
519
1.66
4.62
4.0
8.1
11.10
11.41
mmol/l
0.35
79
469
85
520
1.65
4.59
4.0
8.1
104.42
105.23
mmol/l
0.71
79
470
264
2027
1.33
4.49
2.6
2.3
5.71
7.24
ug/l
1.01
223
1814
318
2507
1.30
4.47
2.2
2.1
0.00
0.01
estimate
1.06
63
553
52
278
1.89
4.45
2.8
2.8
10.26
10.44
mmol/l
0.14
52
273
52
278
1.89
4.45
1.6
2.2
23.00
21.72
mg/l
0.07
17
115
122
819
1.51
4.45
1.5
1.3
10.51
2.29
u/ml
0.53
15
72
119
797
1.51
4.39
1.2
1.2
—
—
—
0
0
63
360
1.77
4.37
2.3
2.5
20.14
41.08
iu/ml
—
9
34
122
823
1.50
4.35
1.4
1.3
13.31
9.18
u/ml
0.22
22
126
128
874
1.48
4.31
1.4
1.2
11.70
35.66
u/ml
—
9
48
84
1315
0.63
4.30
1.1
1.1
1.48
1.52
g/l
1.35
84
1315
106
696
1.54
4.29
3.8
3.5
63.92
62.21
%
0.34
99
678
42
212
1.99
4.26
1.5
1.1
—
—
—
0
0
140
976
1.45
4.25
2.3
2.3
3.65
3.68
g/l
0.06
127
900
140
977
1.45
4.23
2.3
2.3
4.13
4.24
g/l
0.85
127
899
34
159
2.15
4.21
1.2
1.3
134.44
133.52
nmol/l
0.04
34
159
52
284
1.84
4.19
1.7
1.6
67.06
57.65
%
1.05
35
178
97
628
1.56
4.19
1.2
1.1
—
—
—
0
0
14
41
3.43
4.18
2.4
4.2
37.07
40.30
umol/l
0.27
14
32
262
2033
1.32
4.15
1.4
1.3
189.03
242.85
u/ml
0.39
244
1887
17
58
2.94
4.00
1.0
1.1
1.60
6.08
u/ml
0.47
12
49
96
628
1.55
3.98
1.2
1.1
—
—
—
0
0
44
232
1.91
3.96
2.7
3.4
14.45
13.37
index
0.35
29
142
80
504
1.60
3.90
1.9
1.8
—
—
—
0
0
69
419
1.66
3.89
2.2
2.4
5.72
6.25
umol/l
0.19
44
314
81
1245
0.64
3.85
1.1
1.1
0.55
0.63
ratio
—
7
141
897
7989
1.17
3.84
3.9
3.5
46.19
48.59
mg/l
0.11
570
5104
302
2414
1.28
3.83
1.3
1.2
—
—
—
0
0
24
101
2.39
3.81
2.8
2.8
—
—
—
0
0
43
229
1.89
3.78
1.5
1.1
—
—
—
0
0
31
147
2.12
3.74
1.5
1.8
1.30
4.38
nmol/l
1.20
21
118
99
663
1.51
3.71
1.7
1.6
14297.89
11189.52
e6/l
0.41
72
461
14
39
3.60
3.69
2.1
1.6
—
—
—
0
0
73
457
1.61
3.67
1.2
1.3
59.93
32.23
u/l
0.48
62
387
908
8122
1.17
3.65
4.6
4.2
9.26
8.61
mg/mmol
0.13
570
5107
72
450
1.61
3.65
1.3
1.2
6.10
4.63
u/ml
0.40
30
203
32
159
2.02
3.44
1.4
1.5
1.31
1.28
nmol/l
0.04
22
119
13
37
3.52
3.40
2.7
2.4
—
—
—
0
0
22
95
2.33
3.33
2.5
2.9
29.40
29.15
umol/l
0.03
15
68
44
247
1.79
3.32
1.2
1.6
1.16
1.30
promille
0.27
37
199
25
116
2.16
3.22
1.2
1.1
—
—
—
0
0
41
228
1.81
3.20
1.1
1.2
91.25
218.57
titre
—
8
42
55
334
1.66
3.16
1.3
1.3
—
—
nmol/l
—
0
0
274
2223
1.25
3.11
5.1
3.9
—
—
—
0
0
64
409
1.58
3.02
1.6
1.6
—
—
—
0
0
74
492
1.52
2.94
1.3
1.6
—
—
—
0
0
18
76
2.38
2.89
3.7
3.1
—
—
—
0
0
24
116
2.08
2.82
4.0
3.1
—
—
—
0
0
269
2204
1.24
2.82
1.5
1.4
—
—
—
0
0
22
103
2.14
2.80
4.2
3.1
—
—
—
0
0
171
1335
1.30
2.68
1.8
1.7
0.28
0.32
mg/l
0.36
80
640
19
86
2.22
2.63
1.3
1.2
—
—
—
0
0
26
135
1.93
2.55
1.0
1.1
—
—
—
0
0
26
137
1.91
2.45
2.2
2.4
16.27
16.25
%
0.01
26
137
68
464
1.48
2.44
1.2
1.2
—
—
—
0
0
13
51
2.56
2.44
1.2
1.8
—
—
—
0
0
122
926
1.33
2.38
2.0
1.9
—
—
—
0
0
5
8
6.26
2.37
1.0
1.9
1.22
2.37
g/l
—
5
8
2872
28230
1.22
2.32
26.3
18.7
75.96
75.34
umol/l
0.39
2855
27931
161
1274
1.28
2.32
2.0
1.6
292.76
289.77
mu/l
0.04
149
1149
49
316
1.56
2.30
1.3
1.5
277.89
279.85
mosm/kgh2o
0.20
36
238
13
53
2.46
2.27
1.3
1.2
46.15
69.17
ug/l
1.30
13
53
105
787
1.35
2.24
1.1
1.1
3.55
4.42
eliau/ml
—
6
111
261
2188
1.21
2.24
3.0
2.5
6.21
6.11
ph
0.83
155
1439
63
432
1.47
2.23
1.1
1.2
—
—
—
0
0
59
400
1.48
2.21
2.1
1.6
381.77
338.63
mu/l
0.29
48
325
92
677
1.37
2.21
6.1
3.9
3.94
3.88
mmol/l
0.45
92
671
1061
11375
0.90
2.16
3.0
2.9
—
—
—
0
0
432
3796
1.16
2.15
1.6
1.5
—
—
—
0
0
27
152
1.78
2.11
1.5
1.2
—
—
—
0
0
256
2160
1.20
2.07
1.3
1.2
97.02
149.21
u/ml
1.67
86
814
11
44
2.51
2.01
1.8
2.1
—
—
—
0
0
395
3476
1.16
1.94
1.3
1.3
—
—
—
0
0
5
11
4.55
1.94
1.2
1.1
—
—
—
0
0
44
290
1.52
1.92
1.5
1.4
—
—
—
0
0
147
1181
1.26
1.92
2.1
1.9
—
—
—
0
0
140
1119
1.26
1.91
1.3
1.3
169.40
220.98
miu/ml
0.95
54
535
65
464
1.41
1.91
1.6
1.4
18.70
24.02
u/l
0.95
56
385
13
58
2.25
1.90
1.2
1.2
—
—
—
0
0
36
227
1.59
1.90
1.2
1.2
123.00
109.78
pmol/l
0.74
36
227
7
22
3.19
1.88
3.1
2.5
3.11
3.12
mg/l
—
7
22
12
52
2.31
1.87
1.2
1.2
—
—
—
0
0
12
52
2.31
1.87
1.2
1.2
—
—
—
0
0
12
52
2.31
1.87
1.2
1.2
—
—
—
0
0
33
205
1.62
1.85
1.5
1.5
2185.27
2016.86
ml
0.36
33
200
5
12
4.17
1.82
1.2
1.0
—
—
—
0
0
102
789
1.30
1.81
1.3
1.3
—
—
—
0
0
9
35
2.58
1.80
2.4
2.1
1.21
1.33
umol/l
—
9
23
34
216
1.58
1.76
1.6
1.5
26.54
34.12
%
0.54
21
134
17
88
1.94
1.74
1.0
1.0
—
—
—
0
0
23
132
1.75
1.73
1.7
2.9
162.50
144.76
umol/l
—
10
78
19
103
1.85
1.71
2.2
1.6
—
—
—
0
0
33
211
1.57
1.68
1.2
1.2
—
—
—
0
0
10
41
2.44
1.64
1.0
1.5
—
—
—
0
0
46
319
1.45
1.62
2.1
2.3
—
—
—
0
0
61
447
1.37
1.58
4.1
3.5
0.96
0.83
nmol/l
0.42
47
367
29
184
1.58
1.54
1.0
1.0
—
—
—
0
0
14
71
1.98
1.53
1.0
1.1
—
—
—
0
0
14
71
1.98
1.53
1.0
1.1
—
—
—
0
0
14
71
1.98
1.53
1.0
1.1
—
—
—
0
0
7
27
2.60
1.51
1.3
1.2
—
—
—
0
0
16
86
1.86
1.50
1.2
1.1
—
—
—
0
0
2259
23145
0.91
1.49
25.5
18.8
333.06
332.78
g/l
0.71
2246
23007
17
94
1.81
1.47
1.7
1.3
64.00
126.94
nmol/l
—
9
70
24
148
1.63
1.44
1.1
1.1
3.17
29.38
u/ml
—
6
16
42
294
1.43
1.44
1.1
1.1
—
—
—
0
0
14
73
1.92
1.43
1.4
1.2
30.20
39.41
g/l
—
5
40
12
59
2.04
1.43
1.5
1.2
—
—
—
0
0
2563
25142
1.11
1.43
5.2
4.7
5.93
5.86
mmol/l
1.57
2363
23366
7
29
2.42
1.39
1.3
1.2
—
—
—
0
0
11
54
2.04
1.32
3.2
2.9
—
—
—
0
0
87
692
1.26
1.32
1.4
1.3
—
—
—
0
0
237
2698
0.87
1.31
1.7
1.7
3.60
3.49
mmol/l
0.68
155
1838
2843
28080
1.14
1.30
15.1
11.5
27.56
26.65
u/l
1.69
2782
27421
322
3585
0.89
1.27
1.9
1.9
3.54
3.55
ratio
0.06
232
2720
101
822
1.24
1.27
2.0
2.1
3.31
10.50
iu/l
0.55
38
351
8
35
2.29
1.26
1.1
1.0
—
—
—
0
0
61
468
1.31
1.23
1.1
1.1
24.69
1243.26
iu/ml
0.55
14
110
9
45
2.00
1.23
1.2
1.2
60.78
67.00
ug/l
—
9
45
196
1708
1.16
1.18
1.4
1.4
22.87
24.90
iu/l
0.41
166
1451
36
256
1.41
1.17
1.3
1.2
—
—
—
0
0
20
125
1.60
1.17
1.8
1.8
1.17
3.83
u/field
1.18
12
94
5
20
2.50
1.15
1.0
1.0
0.01
0.13
u/ml
—
5
15
136
1158
1.18
1.11
1.3
1.2
—
—
—
0
0
90
737
1.23
1.10
1.1
1.1
1.98
2.28
u/ml
0.13
49
398
76
611
1.25
1.09
1.1
1.1
1.09
1.80
u/ml
0.88
44
314
71
567
1.26
1.08
3.3
2.2
0.90
0.88
nmol/l
0.05
61
485
81
657
1.24
1.08
1.0
1.1
7.29
4.52
u/ml
0.85
53
364
22
144
1.53
1.08
1.6
2.0
29.32
28.95
umol/l
0.07
22
132
45
339
1.33
1.06
3.1
2.6
—
—
—
0
0
216
1913
1.14
1.06
1.3
1.3
—
—
—
0
0
34
245
1.39
1.05
1.1
1.2
30.74
15.34
u/ml
0.52
16
105
16
98
1.64
1.03
1.6
1.7
87.88
97.70
nmol/24h
0.10
16
98
7
34
2.06
1.03
2.0
1.1
—
—
—
0
0
2322
22779
1.08
1.02
24.7
18.2
13.60
13.51
%
2.41
2301
22481
15
91
1.65
1.00
1.1
1.3
27.47
28.35
s
0.12
15
91
286
3153
0.90
0.99
1.3
1.3
—
—
—
0
0
5
23
2.18
0.98
1.2
1.0
—
15.50
—
0
8
35
468
0.74
0.96
1.4
1.6
—
—
—
0
0
716
6770
1.07
0.95
4.7
4.8
2.01
2.36
ug/l
0.74
649
6172
21
141
1.49
0.94
1.0
1.2
—
—
—
0
0
6
29
2.07
0.89
1.2
1.5
—
—
—
0
0
29
211
1.38
0.88
1.2
1.4
135.61
210.80
pmol/l
0.96
29
211
15
95
1.58
0.87
5.1
4.6
—
—
—
0
0
87
732
1.19
0.86
1.1
1.1
—
—
—
0
0
30
221
1.36
0.85
1.2
1.2
—
—
—
0
0
130
1133
1.15
0.84
1.6
1.7
29.44
12.95
u/ml
0.50
36
283
174
1549
1.13
0.83
1.1
1.1
—
—
—
0
0
12
73
1.65
0.81
1.1
1.1
11.49
43.03
iu/ml
3.39
12
73
30
224
1.34
0.79
3.5
2.5
20.37
28.18
mg/l
0.81
19
155
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
71
592
1.20
0.79
3.3
2.9
1.60
1.56
mmol/l
0.11
71
570
60
492
1.22
0.78
1.1
1.1
4.64
4.63
u/ml
0.00
31
221
8
48
1.67
0.78
1.6
1.4
—
—
—
0
0
44
348
1.27
0.78
1.1
1.3
—
—
—
0
0
28
208
1.35
0.77
1.8
1.9
6.95
6.66
mmol/l
0.23
22
151
38
297
1.28
0.75
2.6
2.4
1.21
1.44
g/24h
0.23
25
180
41
324
1.27
0.74
3.3
2.1
1.05
0.89
%
0.57
32
219
5
24
2.08
0.74
1.0
1.0
6.43
8.42
mu/l
—
5
19
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
12
76
1.58
0.71
2.3
2.1
24.57
16.19
umol/l
1.08
12
76
18
126
1.43
0.70
1.1
1.7
—
—
—
0
0
15
101
1.49
0.70
1.0
1.1
—
—
—
0
0
7
41
1.71
0.70
1.0
1.0
1.50
6.54
u/ml
—
7
41
74
629
1.18
0.69
1.0
1.1
0.65
1.16
u/ml
0.84
36
285
57
473
1.21
0.69
1.0
1.0
0.11
0.27
u/ml
0.92
20
159
31
239
1.30
0.69
3.2
2.1
—
—
—
0
0
10
61
1.64
0.68
1.0
1.2
0.06
0.36
u/ml
—
10
61
25
187
1.34
0.68
2.4
2.2
2.64
1.62
u/field
0.37
11
103
29
222
1.31
0.68
1.4
1.4
—
—
—
0
0
26
196
1.33
0.67
1.0
1.1
0.31
2.12
u/ml
0.91
13
69
30
233
1.29
0.64
1.1
1.1
9.18
9.64
iu/ml
0.04
11
67
14
95
1.48
0.64
1.1
1.2
—
—
—
0
0
179
1629
1.10
0.63
1.6
1.7
—
—
—
0
0
18
130
1.39
0.61
2.7
4.0
7.37
9.01
mg/l
0.66
13
110
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
8
53
1.51
0.58
1.1
1.2
137.25
138.73
mmol/l
—
8
44
33
265
1.25
0.56
3.4
5.1
12.84
70.77
u/ml
—
7
89
16
115
1.39
0.56
11.2
7.3
48.81
65.78
mg/l
0.89
16
81
15
206
0.73
0.55
1.2
1.1
—
—
—
0
0
60
514
1.17
0.55
1.1
1.2
—
—
—
0
0
8
122
0.65
0.54
2.0
2.2
1.85
3.34
ug/l
—
8
116
51
431
1.19
0.54
1.1
1.1
2.35
2.39
eliau/ml
0.02
21
205
1100
11305
0.96
0.54
2.0
1.9
1.39
1.40
mmol/l
0.05
907
9783
17
125
1.36
0.53
1.1
1.1
155.50
209.27
iu/ml
0.80
17
125
17
126
1.35
0.51
1.1
1.4
155.47
171.80
mmol/24h
0.33
17
126
66
756
0.87
0.51
1.5
1.5
1.24
1.26
mm
0.20
52
538
12
84
1.43
0.49
1.4
2.0
—
—
—
0
0
19
146
1.30
0.47
1.7
2.2
8.68
8.34
mmol/l
0.11
19
146
120
1094
1.10
0.45
1.6
1.4
—
—
—
0
0
89
990
0.90
0.45
1.5
1.5
61.33
59.21
ug/l
0.18
78
824
68
769
0.88
0.45
1.5
1.5
—
—
—
0
0
24
192
1.25
0.44
1.0
1.1
0.62
0.89
u/ml
—
9
48
30
247
1.22
0.44
1.2
1.3
1.00
1.11
u/ml
0.05
19
132
27
329
0.82
0.43
2.3
2.3
—
—
—
0
0
70
787
0.89
0.43
1.6
1.6
—
—
—
0
0
2516
24945
1.04
0.43
4.3
4.0
1.35
1.29
mmol/l
2.60
2332
23280
23
284
0.81
0.42
1.1
1.2
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
211.20
79.00
titre
—
5
32
26
212
1.23
0.42
1.3
1.5
—
—
—
0
0
2492
24707
1.04
0.41
6.5
5.8
39.29
38.66
mmol/mol
2.65
2343
23398
11
79
1.39
0.40
1.0
1.3
18.50
16.61
umol/l
0.70
11
68
60
530
1.13
0.40
1.1
1.1
4.53
3.59
u/ml
0.20
35
260
0
18
0.00
0.40
0.0
1.4
—
38.33
—
0
18
7
103
0.68
0.39
1.9
1.8
0.00
0.03
estimate
—
7
103
29
242
1.20
0.38
1.6
1.3
140324.50
109650.68
e6/l
0.11
20
162
22
178
1.24
0.38
1.1
1.0
0.27
2.42
u/ml
—
8
38
5
36
1.39
0.38
1.0
1.1
1.37
1.77
umol/24h
—
5
36
258
2447
1.06
0.38
3.8
4.3
20.49
19.77
ug/l
0.02
202
1963
2931
29193
1.06
0.35
32.1
22.6
255.87
254.69
e9/l
0.44
2899
28682
6
42
1.43
0.35
2.0
1.5
3.33
782360.83
nmol/l
—
6
34
31
265
1.17
0.33
1.4
1.4
3761.41
1628.37
e6/l
0.66
22
184
6
46
1.30
0.33
1.2
1.1
—
—
—
0
0
61
549
1.11
0.32
2.5
2.4
91.74
109.64
ug/min
0.18
31
344
2931
29201
1.06
0.32
31.9
22.4
30.23
30.25
pg
0.19
2911
28937
2931
29202
1.06
0.32
32.0
22.5
90.62
90.71
fl
0.52
2911
28939
2931
29204
1.06
0.31
32.7
23.0
40.26
41.07
%
2.22
2910
28927
2931
29206
1.06
0.30
32.0
22.5
4.50
4.53
e12/l
2.76
2889
28625
179
1697
1.06
0.29
1.6
1.6
897.31
999.35
mu/l
1.06
160
1419
7
56
1.25
0.29
1.4
1.3
—
—
—
0
0
2931
29211
1.05
0.28
32.1
22.6
6.94
6.71
e9/l
4.98
2891
28622
33
376
0.88
0.28
1.1
1.2
—
—
—
0
0
10
76
1.32
0.28
2.0
1.5
—
—
—
0
0
26
224
1.16
0.27
1.2
1.1
—
—
—
0
0
2931
29216
1.05
0.27
32.3
22.7
134.95
136.11
g/l
4.39
2912
28955
124
1169
1.06
0.25
1.1
1.1
—
—
—
0
0
11
87
1.27
0.24
1.3
2.2
211432.00
3637.52
e6/l
—
5
50
419
4076
1.03
0.23
3.0
3.0
0.67
0.73
ug/l
0.86
242
2387
5
40
1.25
0.22
2.6
3.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.1
—
439.20
—
0
10
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
345.75
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
2.8
1.3
—
—
—
0
0
6
50
1.20
0.19
7.2
7.4
5.62
5.17
kpa
—
6
50
121
1269
0.95
0.19
3.6
3.3
1.02
1.02
ratio
0.11
106
1145
88
831
1.06
0.19
2.1
2.5
—
—
—
0
0
25
222
1.13
0.19
1.5
1.4
—
—
—
0
0
833
8209
1.02
0.18
1.6
1.5
—
—
—
0
0
51
549
0.93
0.18
4.6
4.2
—
—
—
0
0
25
223
1.12
0.18
1.8
1.5
—
—
—
0
0
20
176
1.14
0.17
2.3
2.3
839.20
615.85
ml
1.17
15
123
17
148
1.15
0.16
1.3
1.9
116.36
103.00
ng/l
0.18
17
148
14
120
1.17
0.16
1.5
1.6
0.58
0.47
e9/l
0.56
14
120
16
139
1.15
0.16
2.5
2.2
521.27
503.97
min
0.33
11
103
9
79
1.14
0.15
1.1
1.5
6.93
8.96
mmol/l
—
9
79
14
121
1.16
0.15
1.2
1.7
—
—
—
0
0
16
181
0.88
0.14
1.2
1.5
27.67
34.70
nmol/l
0.55
16
159
18
160
1.13
0.14
5.1
7.1
6.18
126.23
ug/l
0.62
13
106
17
191
0.89
0.13
1.4
1.5
85.47
78.61
umol/l
0.30
17
191
17
151
1.13
0.13
1.9
2.0
0.30
1.06
u/ml
—
7
44
2630
26228
1.02
0.12
5.0
4.7
1.43
1.45
mmol/l
2.28
2454
24685
55
522
1.05
0.12
5.3
3.5
29.59
26.04
mg/l
0.26
36
364
5
44
1.14
0.10
1.6
1.5
—
—
—
0
0
24
223
1.08
0.09
1.5
1.4
26355.45
62020.67
e6/l
0.53
11
121
2642
26365
1.01
0.09
5.0
4.8
4.65
4.69
mmol/l
1.08
2482
24952
51
488
1.05
0.09
3.9
3.0
7.77
7.39
mmol/l
0.39
51
472
6
55
1.09
0.08
7.2
7.3
5.81
5.97
kpa
—
6
50
2661
26657
0.99
0.08
5.6
5.4
2.73
2.77
mmol/l
1.43
2490
25122
8
94
0.85
0.06
2.9
1.8
40.16
40.53
g/l
—
8
94
58
561
1.03
0.06
1.8
1.5
0.31
0.41
nmol/l
0.65
42
431
10
109
0.92
0.04
3.2
3.2
46.30
44.96
%
—
10
109
10
109
0.92
0.04
6.4
6.3
9.00
8.10
%
—
10
109
83
816
1.02
0.03
9.6
9.4
—
—
—
0
0
14
133
1.05
0.01
1.8
2.4
14.41
262.68
ug/l
0.71
14
116
21
203
1.03
0.01
1.0
1.0
—
—
—
0
0
12
114
1.05
0.00
1.0
1.0
—
—
—
0
0
12
126
0.95
0.00
1.0
1.1
—
—
—
0
0
11
111
0.99
0.00
1.1
1.1
—
—
—
0
0
150
1497
1.00
0.00
3.1
3.4
24.20
62.83
u/ml
3.81
145
1450
16
163
0.98
0.00
1.1
1.2
13.94
8.77
mm/h
0.63
16
163
11
115
0.96
0.00
2.4
1.5
—
—
—
0
0
67
669
1.00
0.00
1.4
1.3
—
—
—
0
0
26
255
1.02
0.00
2.4
2.7
—
—
—
0
0
91
913
1.00
0.00
4.0
3.7
2310.91
1830.30
u/ml
0.09
80
790
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
9
91
0.99
0.00
3.2
2.6
0.64
0.63
mmol/l
—
9
91
6
59
1.02
0.00
2.2
3.2
4.33
5.03
ug/l
—
6
59
8
80
1.00
-0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1278.14
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
32.54
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
105.43
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.3
1.3
47.51
52.64
%
—
7
66
0
5
0.00
-0.00
0.0
1.0
—
8861.20
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
294.86
—
0
7
0
9
0.00
-0.00
0.0
1.3
—
2.30
—
0
9
5
51
0.98
-0.00
1.0
1.4
—
147.50
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
40.14
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
66.87
—
0
7

Mortality – FinRegistry

Association

Association between endpoint AB1_VIRAL_CNS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAL_CNS 1.972 [1.72, 2.26] < 0.001
Birth year 0.992 [0.98, 1.0] 0.077

During the follow-up period (1.1.1998 — 31.12.2019), 1041 out of 7272 females with AB1_VIRAL_CNS died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAL_CNS 1.907 [1.66, 2.2] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 1073 out of 7452 males with AB1_VIRAL_CNS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAL_CNS.

N-year risk Females Males
1 0.143% 0.403%
5 1.046% 2.112%
10 2.439% 5.56%
15 4.779% 10.616%
20 8.764% 17.503%

Relationships between endpoints

Index endpoint: AB1_VIRAL_CNS – Viral infections of the central nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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