No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
194 |
4. Check minimum number of eventsNone |
194 |
5. Include endpointsNone |
194 |
6. Filter based on genotype QC (FinnGen only) |
164 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_CNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Tick-borne viral encephalitis
based on the number of shared cases.
Similar with more cases:
- Viral infections of the central nervous system
- Viral infections of the central nervous system, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1177 | 458 | 710 |
| Only index persons | 1085 | 435 | 650 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 49.62 | 50.46 | 48.87 |
| Only index persons | 50.10 | 50.59 | 49.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 164 | 85 | 79 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.04 |
| Median age at first event (years) | 56.77 | 54.50 | 59.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 180
- Matched controls
- 1800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
+∞
95.5
83
*
A84.9
ICD-10 Finland
Tick-borne viral encephalitis, unspecified
+∞
84.1
74
*
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
39.0
36
*
XA800
NOMESCO Finland
Neuropsychological investigation
11.7
37.2
43
47
TAB00
NOMESCO Finland
Lumbar puncture
9.8
32.5
43
56
R50.9
ICD-10 Finland
Fever, unspecified
6.1
29.8
72
178
AA1AD
NOMESCO Finland
CT of head and brain
5.1
26.3
96
331
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
24.5
23
*
A84.1
ICD-10 Finland
Central European tick-borne encephalitis
+∞
23.4
22
*
A69.2
ICD-10 Finland
Lyme disease
7.9
21.7
33
50
R4120
NOMESCO Finland
Occupational therapy
6.4
18.9
35
65
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
13.7
13
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
11.6
35
98
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
10.8
111
644
N71
ICPC
Meningitis/encephalitis
+∞
10.5
10
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.5
10.3
22
29
0632A
ICD-9 Finland
Tick-borne viral encephalitis, Central European encephalitis[PUUTIAISEN VÄLITTÄMÄ ENKEFALIITTI (KUMLINGE)]
+∞
9.5
9
*
A84
ICD-10 Finland
Tick-borne viral encephalitis
+∞
9.5
9
*
B34.9
ICD-10 Finland
Viral infection, unspecified
9.1
8.0
16
19
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
7.3
7
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
21.0
7.2
10
5
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
7.1
31
110
G03.9
ICD-10 Finland
Meningitis, unspecified
23.5
6.7
9
*
N29
ICPC
Neurological sympt/complt other
11.6
6.4
11
10
S12
ICPC
Insect bite/sting
3.1
6.0
27
97
J01CA04
ATC
amoxicillin; systemic
3.0
6.0
157
1252
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
12
92.62
127.90
1.0
1.0
—
—
—
0
0
65
17
59.28
110.23
1.1
1.6
—
—
—
0
0
99
7
309.80
106.49
1.4
1.1
—
—
—
0
0
71
42
27.26
90.85
1.1
1.3
75.89
3115.97
e6/l
0.54
35
31
69
41
26.67
87.95
1.1
1.2
88.50
5.62
e6/l
2.83
32
29
101
121
17.74
87.39
3.4
2.6
20.81
12.69
au/ml
0.65
20
12
97
110
17.96
86.94
1.8
1.3
60.49
24.61
au/ml
—
12
9
68
5
216.25
69.61
1.0
1.4
—
—
—
0
0
54
8
95.42
50.48
1.1
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
49
7
95.23
45.75
1.0
1.4
—
—
—
0
0
29
10
34.21
22.68
1.2
1.4
2.15
1.87
mmol/l
—
29
10
31
47
7.76
20.29
1.1
1.3
—
—
—
0
0
22
6
41.43
18.07
1.1
1.3
—
—
—
0
0
22
6
41.43
18.07
1.1
1.2
—
—
—
0
0
22
6
41.43
18.07
1.1
1.3
—
—
—
0
0
73
266
3.93
17.29
1.5
2.0
—
—
—
0
0
39
91
5.19
16.43
1.4
1.9
—
—
—
0
0
59
200
3.90
15.27
1.4
1.9
—
—
—
0
0
19
6
35.12
15.14
1.1
1.2
—
—
—
0
0
19
6
35.12
15.14
1.1
1.3
—
—
—
0
0
18
6
33.07
14.18
1.1
1.0
—
—
—
0
0
23
20
13.00
13.25
1.2
2.2
—
—
—
0
0
20
13
17.12
12.96
1.1
1.0
—
—
—
0
0
25
50
5.65
12.35
1.4
2.1
—
—
—
0
0
22
22
11.22
11.89
1.0
1.2
—
—
—
0
0
16
7
24.89
11.79
1.0
1.1
—
—
—
0
0
19
18
11.65
10.57
1.2
2.3
—
—
—
0
0
50
195
3.17
9.99
1.5
1.9
—
—
—
0
0
64
297
2.79
9.28
2.3
3.0
0.58
0.95
e6/l
0.87
26
147
59
272
2.74
8.58
2.3
3.2
4.21
1.84
e6/l
0.49
20
123
17
30
6.14
6.64
1.0
1.3
232.36
247.45
u/ml
0.08
11
11
81
482
2.24
6.42
2.7
3.2
0.29
0.43
e6/l
0.55
49
344
108
726
2.22
6.28
5.3
6.6
1.20
1.22
mmol/l
2.40
96
677
155
1227
2.90
6.05
8.2
8.7
73.23
81.11
u/l
1.63
150
1168
136
1017
2.38
5.94
2.9
3.2
—
—
—
0
0
129
949
2.27
5.77
8.8
11.0
4.50
4.10
e9/l
0.72
110
817
16
33
5.22
5.59
1.0
1.4
—
—
—
0
0
121
881
2.14
5.37
5.4
7.1
10.62
11.37
umol/l
0.54
115
840
111
794
2.04
5.03
5.7
7.5
1.21
1.21
mmol/l
0.59
98
694
17
51
3.58
5.02
1.2
2.4
—
—
—
0
0
16
47
3.64
4.87
1.3
1.5
—
—
—
0
0
146
1184
2.23
4.37
4.4
4.3
11.23
11.64
mm/h
0.16
141
1115
7
6
12.06
4.31
1.1
1.0
1200.86
1825.67
miu/ml
—
7
6
14
41
3.62
4.28
1.1
7.1
—
353.80
—
0
5
13
31
4.44
4.10
1.0
1.4
186.00
151.76
au/ml
—
5
11
172
1551
3.45
3.98
19.3
16.1
21.41
23.48
mg/l
0.44
164
1282
91
665
1.75
3.34
2.2
2.1
94.54
95.54
pmol/l
0.06
46
334
50
308
1.86
3.24
3.5
4.0
82.79
193.68
ng/l
0.51
38
237
14
51
2.89
3.06
1.1
1.8
—
—
—
0
0
12
37
3.40
3.00
1.1
1.6
—
—
—
0
0
7
16
4.51
2.50
1.0
2.0
—
—
—
0
0
7
16
4.51
2.50
1.0
2.0
—
—
—
0
0
7
16
4.51
2.50
1.0
2.0
—
—
—
0
0
23
119
2.07
2.44
1.4
1.7
—
—
—
0
0
5
9
5.68
2.23
3.6
1.8
369.60
1060.00
u/ml
—
5
9
65
474
1.58
2.19
1.7
1.7
18.76
21.88
nmol/l
1.28
52
402
59
422
1.59
2.15
2.5
3.0
342.06
346.16
umol/l
0.11
51
378
89
701
1.53
2.11
3.3
4.9
35.11
35.88
g/l
0.70
84
666
5
10
5.11
2.08
1.0
1.0
—
—
—
0
0
5
10
5.11
2.08
1.0
2.1
—
—
—
0
0
5
10
5.11
2.08
1.0
2.1
—
—
—
0
0
5
10
5.11
2.08
1.0
2.1
—
—
—
0
0
5
10
5.11
2.08
1.0
2.1
—
—
—
0
0
6
16
3.84
1.95
1.2
1.0
—
—
—
0
0
13
59
2.30
1.89
1.2
1.2
—
—
—
0
0
28
172
1.74
1.81
8.2
8.2
2.01
0.91
mmol/l
0.95
22
149
86
689
1.48
1.80
2.6
2.6
72.71
74.86
nmol/l
0.29
74
626
19
103
1.94
1.80
10.5
7.8
25.46
24.70
mmol/l
0.52
19
103
17
89
2.01
1.77
1.4
3.3
0.52
0.60
%
0.75
17
89
49
353
1.53
1.70
1.7
1.7
0.80
1.32
mg/l
1.44
35
285
66
515
1.44
1.53
2.1
2.6
52.72
75.40
u/l
1.13
60
483
30
197
1.63
1.53
6.0
4.6
33.33
32.54
%
0.13
15
129
9
39
2.37
1.45
1.1
1.5
—
—
—
0
0
100
848
1.40
1.43
3.1
3.8
171.00
9.44
estimate
—
9
199
16
89
1.88
1.42
1.4
3.3
0.87
1.18
%
1.55
16
89
26
168
1.64
1.41
6.0
8.0
—
—
—
0
0
99
840
1.40
1.40
3.1
3.7
0.00
0.00
estimate
—
9
196
101
861
1.39
1.38
3.1
3.8
0.00
0.00
estimate
—
9
176
6
134
0.43
1.34
3.8
4.4
1.21
1.22
mmol/l
—
6
119
155
1433
1.59
1.33
5.3
5.3
1.67
1.94
mu/l
2.53
142
1323
11
55
2.07
1.30
1.1
1.1
—
—
—
0
0
11
55
2.07
1.30
1.1
2.1
0.00
0.00
g/l
-0.00
11
55
134
1206
1.43
1.29
3.7
4.2
14.78
14.80
pmol/l
0.04
119
1106
8
35
2.34
1.28
1.8
1.3
—
—
—
0
0
127
1133
1.41
1.28
3.1
3.4
50.77
48.33
u/l
0.12
122
1071
50
383
1.42
1.26
2.3
2.2
—
—
—
0
0
86
722
1.37
1.26
3.0
3.1
139.31
122.92
ug/l
0.28
76
679
11
56
2.03
1.25
1.1
1.1
—
—
—
0
0
5
19
2.68
1.22
1.4
1.2
—
—
—
0
0
5
19
2.68
1.22
3.2
5.0
2.36
3.53
nmol/l
—
5
19
162
1521
1.65
1.20
19.4
15.9
86.13
82.39
ml/min/173m2
1.74
150
1407
8
40
2.05
1.13
1.0
1.4
—
—
—
0
0
14
81
1.79
1.12
1.1
1.4
—
—
—
0
0
74
617
1.34
1.10
3.1
3.8
60.44
35.46
ng/l
0.27
55
443
5
21
2.42
1.10
1.4
1.3
—
—
—
0
0
17
106
1.67
1.07
12.2
10.7
95.61
93.65
%
1.76
17
106
7
34
2.10
1.04
1.3
1.6
—
—
—
0
0
7
34
2.10
1.04
1.3
1.6
—
—
—
0
0
22
149
1.54
1.01
1.4
1.4
—
—
—
0
0
7
36
1.98
0.98
1.1
1.9
—
—
—
0
0
21
143
1.53
0.95
1.8
2.7
0.23
0.22
g/l
0.31
21
133
9
52
1.77
0.94
1.1
1.6
—
—
—
0
0
40
314
1.35
0.87
1.7
1.6
—
—
—
0
0
8
45
1.81
0.85
1.0
1.3
—
59.38
—
0
8
6
31
1.97
0.85
1.2
1.5
—
—
—
0
0
31
236
1.38
0.81
8.1
7.3
103.26
104.54
mmol/l
1.03
31
236
54
636
0.78
0.75
2.8
3.6
0.00
0.00
estimate
—
7
168
174
1693
1.83
0.75
28.4
24.3
90.79
91.11
fl
0.37
174
1682
174
1694
1.81
0.75
29.6
24.8
39.80
40.79
%
1.61
174
1682
11
169
0.63
0.73
2.5
3.5
—
—
—
0
0
13
85
1.57
0.71
1.0
1.0
—
—
—
0
0
48
399
1.28
0.70
2.3
2.2
2.97
2.72
mg/l
0.19
38
352
56
476
1.26
0.68
2.9
3.3
829.05
1209.91
ng/l
0.83
48
392
42
345
1.28
0.67
3.8
3.2
0.46
0.73
ug/l
3.50
23
219
174
1696
1.78
0.64
28.8
24.5
134.16
136.52
g/l
1.70
174
1683
13
88
1.51
0.62
1.6
2.2
—
—
—
0
0
8
51
1.59
0.61
1.1
1.3
—
—
—
0
0
11
72
1.56
0.60
2.0
2.2
32.82
40.31
u/l
0.85
11
66
64
561
1.22
0.58
6.8
5.3
2.93
1.82
ug/l
0.50
55
505
18
133
1.39
0.57
1.8
1.9
3.52
3.60
mmol/l
0.12
11
98
48
409
1.24
0.57
1.3
1.3
0.57
1.22
u/ml
—
9
119
52
449
1.22
0.55
4.2
4.6
21.04
22.01
%
0.14
19
211
18
136
1.36
0.51
1.6
2.9
0.30
0.29
e6/l
0.03
18
131
34
283
1.25
0.50
1.3
1.3
1.47
5.39
u/ml
—
10
114
7
48
1.48
0.47
1.3
1.9
—
—
—
0
0
155
1495
1.26
0.46
4.9
4.3
1.23
1.31
mmol/l
1.02
138
1388
28
230
1.26
0.46
1.6
1.5
—
—
—
0
0
12
86
1.42
0.46
1.1
1.3
—
—
—
0
0
41
473
0.83
0.45
2.0
3.0
0.00
0.00
estimate
—
7
158
40
462
0.83
0.45
3.6
4.1
0.00
0.00
estimate
—
8
180
37
315
1.22
0.45
1.4
1.3
60.57
26.36
iu/ml
—
7
102
5
31
1.63
0.43
2.4
3.4
15.00
43.13
u/ml
—
5
31
8
58
1.40
0.42
2.6
2.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
128
1333
0.86
0.35
25.6
20.1
13.55
13.57
%
0.06
128
1327
22
182
1.24
0.35
2.0
2.1
3.37
3.63
ratio
0.47
15
152
6
46
1.31
0.33
1.2
1.5
—
—
—
0
0
10
74
1.37
0.33
1.7
2.2
—
—
—
0
0
59
538
1.14
0.33
3.7
3.6
2.33
2.35
mmol/l
0.49
48
494
7
53
1.33
0.31
1.4
1.2
—
—
—
0
0
66
705
0.90
0.25
2.1
1.9
1.45
1.39
mmol/l
0.19
53
595
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
13.52
—
0
11
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
12.75
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
53
1.14
0.19
1.0
1.4
—
—
—
0
0
21
187
1.14
0.16
2.1
1.9
307.81
391.91
nmol/l
1.44
21
175
76
728
1.08
0.15
2.6
2.6
—
—
estimate
—
0
0
148
1504
0.91
0.14
5.2
5.0
5.97
5.94
mmol/l
0.07
131
1396
27
248
1.10
0.13
1.4
1.7
774.11
1178.90
nmol/l
2.09
18
190
52
546
0.93
0.12
3.3
4.0
5.01
9.19
mg/mmol
1.13
31
344
158
1560
1.10
0.12
5.9
5.1
4.77
4.64
mmol/l
0.94
143
1470
5
46
1.09
0.09
1.2
1.4
—
—
—
0
0
157
1554
1.08
0.08
5.7
5.1
1.48
1.44
mmol/l
0.64
142
1455
5
62
0.80
0.08
1.2
1.5
—
—
—
0
0
37
357
1.05
0.05
3.0
4.0
1.01
1.02
kg/l
1.68
26
237
147
1476
0.98
0.00
6.4
6.3
38.84
39.38
mmol/mol
0.29
136
1409
20
198
1.01
0.00
2.0
2.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
110.20
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
9.49
—
0
6
0
9
0.00
-0.00
0.0
3.8
—
92.00
—
0
9
0
6
0.00
-0.00
0.0
11.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
2.8
—
114.50
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
57
0.87
-0.00
1.0
1.4
—
2.74
—
0
13
0
8
0.00
-0.00
0.0
2.4
—
58.38
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
95
0.94
-0.00
1.2
1.2
—
123.09
—
0
34
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
4.2
3.4
1485.33
1162.41
u/ml
—
6
54
18
180
1.00
-0.00
1.8
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
70.44
—
0
8
0
7
0.00
-0.00
0.0
4.0
—
1.14
—
0
7
158
1580
1.00
-0.00
6.4
5.8
2.85
2.73
mmol/l
0.94
141
1485
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TICK_BORNE_ENCEPHALITIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_TICK_BORNE_ENCEPHALITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_TICK_BORNE_ENCEPHALITIS – Tick-borne viral encephalitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data