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Tick-borne viral encephalitis

EFO Endpoint Browser PheWeb

AB1_TICK_BORNE_ENCEPHALITIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A84
  • Hospital discharge: ICD-9 — 06[3]
  • Hospital discharge: ICD-8 — 06[3]
  • Cause of death: ICD-10 — A84
  • Cause of death: ICD-9 — 06[3]
  • Cause of death: ICD-8 — 06[3]

2 out of 7 registries used, show all original rules.

180

4. Check minimum number of events

None

180

5. Include endpoints

None

180

6. Filter based on genotype QC (FinnGen only)

164

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1177 458 710
Only index persons 1085 435 650
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 49.62 50.46 48.87
Only index persons 50.10 50.59 49.77

-FinnGen-

Key figures

All Female Male
Number of individuals 164 85 79
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 56.77 54.50 59.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
180
Matched controls
1800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
+∞
95.5
83
*
A84.9
ICD-10 Finland
Tick-borne viral encephalitis, unspecified
+∞
84.1
74
*
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
39.0
36
*
XA800
NOMESCO Finland
Neuropsychological investigation
11.7
37.2
43
47
TAB00
NOMESCO Finland
Lumbar puncture
9.8
32.5
43
56
R50.9
ICD-10 Finland
Fever, unspecified
6.1
29.8
72
178
AA1AD
NOMESCO Finland
CT of head and brain
5.1
26.3
96
331
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
24.5
23
*
A84.1
ICD-10 Finland
Central European tick-borne encephalitis
+∞
23.4
22
*
A69.2
ICD-10 Finland
Lyme disease
7.9
21.7
33
50
R4120
NOMESCO Finland
Occupational therapy
6.4
18.9
35
65
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
13.7
13
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
11.6
35
98
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
10.8
111
644
N71
ICPC
Meningitis/encephalitis
+∞
10.5
10
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.5
10.3
22
29
A84
ICD-10 Finland
Tick-borne viral encephalitis
+∞
9.5
9
*
0632A
ICD-9 Finland
Tick-borne viral encephalitis, Central European encephalitis[PUUTIAISEN VÄLITTÄMÄ ENKEFALIITTI (KUMLINGE)]
+∞
9.5
9
*
B34.9
ICD-10 Finland
Viral infection, unspecified
9.1
8.0
16
19
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
7.3
7
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
21.0
7.2
10
5
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
7.1
31
110
G03.9
ICD-10 Finland
Meningitis, unspecified
23.5
6.7
9
*
N29
ICPC
Neurological sympt/complt other
11.6
6.4
11
10
S12
ICPC
Insect bite/sting
3.1
6.0
27
97
J01CA04
ATC
amoxicillin; systemic
3.0
6.0
157
1252

TimeCodeWAS

↥

TODO / Current known limitations:

  • Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
  • Legend / how to read the glyphs.
  • Proper column names.
  • Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
  • Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
  • Download CSV not working.
  • No filters and sorters.
  • Limited amount of endpoints with TimeCodeWAS data.
  • Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
Unspecified viral encephalitis
A86 (45542542)
Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
22126-7 (3010380)
Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
22118-4 (3011166)
Hantavirus puumala IgG Ab [Titer] in Serum
22308-1 (3012447)
Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
22133-3 (3014973)
Differential panel - Cerebral spinal fluid
29584-0 (3016018)
Leukocytes [#/volume] in Cerebral spinal fluid
26465-5 (3016543)
Protein [Mass/volume] in Cerebral spinal fluid
2880-3 (3019473)
Glucose [Moles/volume] in Cerebral spinal fluid
14744-7 (3020044)
Appearance of Cerebral spinal fluid
10333-3 (3023410)
Erythrocytes [#/volume] in Cerebral spinal fluid
26454-9 (3027475)
Lactate [Moles/volume] in Cerebral spinal fluid
2520-5 (3035999)
Cell count panel - Cerebral spinal fluid
34563-7 (3044290)
Body height measure
50373000 (4177340)
Body mass index
60621009 (4245997)
Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
70058-3 (42868544)
Other tick-borne viral encephalitis
A84.8 (45532856)
Very extensive MRI examination of brain with high intensity magnet
AA1DG (2001300120)
Occupational therapy
R4120 (2001310234)
Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
18243-6 (3002823)
Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5013-8 (3008733)
Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21598-8 (3016894)
Bacteria identified in Cerebral spinal fluid by Culture
606-4 (3016914)
Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
41602-4 (3033386)
Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
42991-0 (3037677)
Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
41150-4 (3044212)
Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
40988-8 (3044254)
European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
69923-1 (42868414)
European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
69924-9 (42868415)
European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay
69926-4 (42868417)
CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
74917-6 (44816808)
Central European tick-borne encephalitis
A84.1 (45532855)
Tick-borne viral encephalitis, unspecified
A84.9 (45571447)
Viral meningitis, unspecified
A87.9 (45600441)
Standard MRI examination of brain with high intensity magnet
AA1BG (2001300112)
Extensive MRI examination of brain with high intensity magnet
AA1CG (2001300116)
Neuropsychological investigation
XA800 (2001300412)
Lumbar puncture
TAB00 (2001300538)
Physiotherapy
R4110 (2001310233)
Fever
A03 (2002000144)
Abnormal result investigation NOS
A91 (2002000224)
Borrelia burgdorferi IgM Ab [Units/volume] in Serum
7818-8 (3008230)
Enterovirus RNA [Presence] in Specimen by NAA with probe detection
29591-5 (3016881)
Borrelia burgdorferi IgG Ab [Units/volume] in Serum
7817-0 (3016888)
Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
7993-9 (3025023)
Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
40729-6 (3041145)
Herpes simplex virus Ab [Presence] in Cerebral spinal fluid
44506-4 (3043525)
Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
40987-0 (3043924)
Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
95941-1 (36031861)
Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
58755-0 (40761849)
European tick borne encephalitis virus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay
69927-2 (42868418)
Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
69930-6 (42868421)
Fever, unspecified
R50.9 (45582716)
Lyme disease
A69.2 (45595594)
Headache
R51.80 (2000503603)
Emergency Room and Inpatient Visit
ERIP (262)
Bilirubin.total [Moles/volume] in Serum or Plasma
14631-6 (3006140)
Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
2157-6 (3007220)
Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method
4537-7 (3013707)
Troponin T.cardiac [Mass/volume] in Serum or Plasma
6598-7 (3019800)
Varicella zoster virus Ab [Titer] in Cerebral spinal fluid
21592-1 (3023365)
Prothrombin time (PT) actual/Normal
5894-1 (3033658)
Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40982-1 (3038288)
Neurology
13 (38004458)
Infectious Disease
44 (38004484)
Viral infection, unspecified
B34.9 (45605229)
Inpatient Hospital
21 (8717)
Outpatient Hospital
22 (8756)
C reactive protein [Mass/volume] in Serum or Plasma
1988-5 (3020460)
Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)
Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)
Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)
Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)
MCH [Entitic mass]
28539-5 (3035941)
MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)
Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)
Erythrocytes [#/volume] in Blood
26453-1 (3026361)
Platelets [#/volume] in Blood
26515-7 (3007461)
Hemoglobin [Mass/volume] in Blood
718-7 (3000963)
Leukocytes [#/volume] in Blood
26464-8 (3010813)
MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)
Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)
Laboratory Visit
OMOP4822461 (32036)
Bacteria [Presence] in Urine
87829-8 (36304419)
Casts [#/volume] in Urine by Automated count
51483-6 (3030467)
Differential panel, method unspecified - Blood
69738-3 (42870588)
Epithelial cells.squamous [#/volume] in Urine by Automated count
51486-9 (3029879)
Erythrocytes [#/volume] in Urine
30391-7 (3002582)
Internal Medicine
11 (38004456)
Epithelial cells.non-squamous [#/volume] in Urine by Automated count
51485-1 (3030306)
Leukocytes [#/volume] in Urine
30405-5 (3018095)
Basophils/Leukocytes in Blood
30180-4 (3022096)
Eosinophils/Leukocytes in Blood
26450-7 (3006504)
Monocytes/Leukocytes in Blood
26485-3 (3019069)
INR in Blood by Coagulation assay
34714-6 (3032080)
doxycycline; oral, parenteral
J01AA02 (21602800)
Urinalysis microscopic panel [#/volume] - Urine by Automated count
50554-5 (3029287)
Basophils [#/volume] in Blood
26444-0 (3006315)
Neutrophils/Leukocytes in Blood
26511-6 (3018010)
Lymphocytes/Leukocytes in Blood
26478-8 (3002030)
Lymphocytes [#/volume] in Blood
26474-7 (3019198)
Monocytes [#/volume] in Blood
26484-6 (3001604)
Eosinophils [#/volume] in Blood
26449-9 (3013115)
Bacteria [#/volume] in Urine by Automated count
51480-2 (3031040)
Calcium.ionized [Moles/volume] in Serum or Plasma
1995-0 (3021347)
Supplier / Service Provider
OMOP5117446 (33004)
Emergency Room Visit
ER (9203)
Neutrophils [#/volume] in Blood by Automated count
751-8 (3013650)
Emergency Medicine
93 (38004510)
Glucose [Moles/volume] in Serum or Plasma
14749-6 (3013826)
Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
6768-6 (3035995)
Urinalysis macro (dipstick) panel - Urine
24357-6 (3037467)
Normoblasts [#/volume] in Blood
715-3 (3021589)
Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19072-8 (3016431)
Outpatient Visit
OP (9202)
Thorax X-ray examination
GD1AA (2001303617)
Case Management Agency
251B00000X (38004193)
Bacteria identified in Blood by Culture
600-7 (3023368)
Hemoglobin [Presence] in Urine by Test strip
5794-3 (3011397)
SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
94500-6 (706163)
Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1742-6 (3006923)
Ketones [Presence] in Urine by Test strip
2514-8 (3035350)
pH of Urine
2756-5 (3015736)
Nitrite [Presence] in Urine by Test strip
5802-4 (3021601)
Glucose [Presence] in Urine by Test strip
25428-4 (3009261)
CBC panel - Blood by Automated count
58410-2 (40761511)
Thyrotropin [Units/volume] in Serum or Plasma
3016-3 (3009201)
ibuprofen
R02AX02 (1588667)
ibuprofen; oral, parenteral, rectal
M01AE01 (21603967)

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
70
18
63.00
119.65
1.1
1.5
—
—
—
0
0
80
33
42.84
119.64
1.1
1.3
—
—
—
0
0
71
42
27.26
90.85
1.1
1.3
75.89
3115.97
e6/l
0.54
35
31
69
41
26.67
87.95
1.1
1.2
88.50
5.62
e6/l
2.83
32
29
101
121
17.74
87.39
3.4
2.6
20.81
12.69
au/ml
0.65
20
12
97
110
17.96
86.94
1.8
1.3
60.49
24.61
au/ml
—
12
9
54
22
34.64
79.42
1.1
1.5
—
—
—
0
0
41
17
30.94
59.23
1.1
1.1
—
—
—
0
0
118
433
6.01
31.19
3.4
4.8
—
—
—
0
0
29
10
34.21
22.68
1.2
1.4
2.15
1.87
mmol/l
—
29
10
104
562
3.01
11.93
5.9
6.3
—
—
—
0
0
125
790
2.91
10.03
6.5
6.9
8.82
8.69
%
0.18
119
745
125
793
2.89
9.91
6.4
6.8
58.35
57.74
%
0.18
120
758
124
788
2.84
9.71
6.5
6.8
0.56
0.71
%
2.41
118
734
79
403
2.71
9.58
3.6
4.4
87.27
92.50
%
1.32
79
398
14
10
15.05
8.85
1.1
1.0
—
—
—
0
0
122
792
2.68
8.77
6.5
6.8
2.17
2.88
%
1.84
116
745
59
272
2.74
8.58
2.3
3.2
4.21
1.84
e6/l
0.49
20
123
16
19
9.12
8.00
1.0
1.2
—
—
—
0
0
125
859
2.49
7.37
6.7
6.9
0.04
0.04
e9/l
1.41
106
722
124
856
2.44
7.13
6.7
6.9
0.58
0.58
e9/l
0.10
105
723
126
881
2.43
6.96
6.9
7.3
0.13
0.20
e9/l
6.14
111
763
125
871
2.42
6.96
6.7
6.9
1.72
1.78
e9/l
0.22
109
759
17
30
6.14
6.64
1.0
1.3
232.36
247.45
u/ml
0.08
11
11
59
305
2.39
6.53
1.6
1.9
—
—
—
0
0
81
482
2.24
6.42
2.7
3.2
0.29
0.43
e6/l
0.55
49
344
19
52
3.97
6.39
1.2
1.4
—
—
—
0
0
89
553
2.21
6.32
2.8
3.4
34.06
171.28
e6/l
0.60
61
417
108
726
2.22
6.28
5.3
6.6
1.20
1.22
mmol/l
2.40
96
677
96
617
2.19
6.23
2.3
2.2
—
—
—
0
0
97
628
2.18
6.16
3.7
4.0
23.18
86.77
e6/l
1.37
64
437
155
1227
2.90
6.05
8.2
8.7
73.23
81.11
u/l
1.63
150
1168
129
949
2.27
5.77
8.8
11.0
4.50
4.10
e9/l
0.72
110
817
121
881
2.14
5.37
5.4
7.1
10.62
11.37
umol/l
0.54
115
840
111
794
2.04
5.03
5.7
7.5
1.21
1.21
mmol/l
0.59
98
694
30
134
2.49
4.46
3.4
4.8
7.40
7.36
ph
0.87
18
97
7
6
12.06
4.31
1.1
1.0
1200.86
1825.67
miu/ml
—
7
6
13
31
4.44
4.10
1.0
1.4
186.00
151.76
au/ml
—
5
11
172
1551
3.45
3.98
19.3
16.1
21.41
23.48
mg/l
0.44
164
1282
91
665
1.75
3.34
2.2
2.1
94.54
95.54
pmol/l
0.06
46
334
50
308
1.86
3.24
3.5
4.0
82.79
193.68
ng/l
0.51
38
237
21
95
2.37
3.04
1.0
1.1
—
—
—
0
0
24
116
2.23
2.99
1.5
2.4
—
—
—
0
0
10
27
3.86
2.93
1.2
1.1
—
—
—
0
0
10
27
3.86
2.93
1.2
1.1
—
—
—
0
0
10
29
3.59
2.74
1.1
1.0
—
—
—
0
0
67
477
1.64
2.55
2.4
2.7
—
0.22
—
0
9
10
32
3.25
2.48
1.1
1.1
—
—
—
0
0
54
366
1.68
2.47
1.3
1.4
2.02
2.63
g/l
1.64
27
213
0
66
0.00
2.46
0.0
3.8
—
1.49
—
0
59
26
142
1.97
2.39
1.5
1.7
—
—
—
0
0
24
128
2.01
2.35
1.5
1.8
6.56
6.05
ph
—
8
87
8
24
3.44
2.21
1.0
1.1
—
—
—
0
0
65
474
1.58
2.19
1.7
1.7
18.76
21.88
nmol/l
1.28
52
402
59
422
1.59
2.15
2.5
3.0
342.06
346.16
umol/l
0.11
51
378
8
25
3.30
2.12
1.4
1.1
—
—
—
0
0
89
701
1.53
2.11
3.3
4.9
35.11
35.88
g/l
0.70
84
666
86
675
1.52
2.06
2.8
3.4
6.17
6.20
ph
0.05
35
378
7
21
3.42
1.98
1.3
1.3
—
—
—
0
0
29
175
1.78
1.98
7.9
8.0
7.42
7.42
ph
0.03
13
101
67
509
1.50
1.82
2.5
4.3
7.41
7.40
ph
1.38
46
372
28
172
1.74
1.81
8.2
8.2
2.01
0.91
mmol/l
0.95
22
149
19
103
1.94
1.80
10.5
7.8
25.46
24.70
mmol/l
0.52
19
103
49
657
0.65
1.78
2.6
3.2
—
—
—
0
0
17
89
2.01
1.77
1.4
3.3
0.52
0.60
%
0.75
17
89
49
353
1.53
1.70
1.7
1.7
0.80
1.32
mg/l
1.44
35
285
67
516
1.48
1.69
7.1
6.5
—
—
—
0
0
8
31
2.65
1.68
1.3
1.6
—
—
—
0
0
0
43
0.00
1.54
0.0
13.2
—
—
—
0
0
36
247
1.57
1.54
1.3
1.4
120.00
612.88
titre
—
7
59
66
515
1.44
1.53
2.1
2.6
52.72
75.40
u/l
1.13
60
483
6
21
2.92
1.52
1.2
1.3
26.17
25.12
ng/l
—
6
21
86
707
1.41
1.49
11.0
12.5
1.20
1.20
inr
0.01
67
590
11
52
2.19
1.47
1.4
1.2
—
—
—
0
0
100
848
1.40
1.43
3.1
3.8
171.00
9.44
estimate
—
9
199
16
89
1.88
1.42
1.4
3.3
0.87
1.18
%
1.55
16
89
99
840
1.40
1.40
3.1
3.7
0.00
0.00
estimate
—
9
196
101
861
1.39
1.38
3.1
3.8
0.00
0.00
estimate
—
9
176
15
83
1.88
1.36
1.4
1.2
—
—
—
0
0
6
134
0.43
1.34
3.5
3.6
—
—
—
0
0
6
134
0.43
1.34
3.8
4.4
1.21
1.22
mmol/l
—
6
119
155
1433
1.59
1.33
5.3
5.3
1.67
1.94
mu/l
2.53
142
1323
6
24
2.55
1.31
1.5
1.7
—
—
—
0
0
6
24
2.55
1.31
2.0
1.7
—
—
—
0
0
11
55
2.07
1.30
1.1
1.1
—
—
—
0
0
134
1206
1.43
1.29
3.7
4.2
14.78
14.80
pmol/l
0.04
119
1106
127
1133
1.41
1.28
3.1
3.4
50.77
48.33
u/l
0.12
122
1071
36
258
1.49
1.27
1.6
1.6
—
—
—
0
0
86
722
1.37
1.26
3.0
3.1
139.31
122.92
ug/l
0.28
76
679
30
207
1.54
1.26
1.5
1.6
—
—
—
0
0
25
166
1.59
1.23
1.6
4.3
7.38
7.38
ph
0.04
11
94
5
19
2.68
1.22
3.2
5.0
2.36
3.53
nmol/l
—
5
19
22
142
1.63
1.21
1.2
1.2
—
—
—
0
0
90
766
1.35
1.19
9.3
12.1
0.00
0.00
e9/l
0.01
67
617
74
617
1.34
1.10
3.1
3.8
60.44
35.46
ng/l
0.27
55
443
23
155
1.55
1.07
9.1
8.8
—
—
—
0
0
17
106
1.67
1.07
12.2
10.7
95.61
93.65
%
1.76
17
106
62
507
1.34
1.04
2.4
2.3
—
—
—
0
0
9
47
1.96
1.04
1.0
1.1
—
—
—
0
0
12
68
1.82
1.03
1.6
1.7
—
—
—
0
0
12
69
1.79
0.99
2.5
2.4
—
—
—
0
0
28
377
0.70
0.97
4.9
5.8
—
—
—
0
0
11
62
1.82
0.96
1.2
1.5
—
—
—
0
0
21
143
1.53
0.95
1.8
2.7
0.23
0.22
g/l
0.31
21
133
14
87
1.66
0.90
1.1
1.7
—
5.77
—
0
20
6
111
0.52
0.86
1.5
1.2
229.17
350.55
u/ml
—
6
101
11
65
1.74
0.84
1.2
1.5
—
—
—
0
0
6
32
1.90
0.82
1.0
1.7
—
—
—
0
0
31
236
1.38
0.81
8.1
7.3
103.26
104.54
mmol/l
1.03
31
236
26
192
1.41
0.81
1.7
1.6
—
—
—
0
0
11
66
1.71
0.80
1.2
1.5
—
—
—
0
0
21
149
1.46
0.80
2.7
3.5
90.99
74.77
e9/l
0.73
13
106
0
24
0.00
0.80
0.0
3.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.8
—
9.68
—
0
25
20
141
1.47
0.78
1.6
1.5
—
—
—
0
0
11
67
1.68
0.77
1.2
1.5
—
—
—
0
0
11
67
1.68
0.77
1.2
1.5
—
—
—
0
0
54
636
0.78
0.75
2.8
3.6
0.00
0.00
estimate
—
7
168
174
1693
1.83
0.75
28.4
24.3
90.79
91.11
fl
0.37
174
1682
174
1694
1.81
0.75
28.4
24.3
30.30
30.39
pg
0.25
174
1683
174
1694
1.81
0.75
29.6
24.8
39.80
40.79
%
1.61
174
1682
5
24
2.11
0.75
1.4
1.6
—
—
—
0
0
53
445
1.27
0.71
2.2
3.0
—
—
—
0
0
48
399
1.28
0.70
2.3
2.2
2.97
2.72
mg/l
0.19
38
352
42
345
1.28
0.67
3.8
3.2
0.46
0.73
ug/l
3.50
23
219
19
138
1.42
0.65
1.3
1.4
—
—
—
0
0
27
209
1.34
0.65
1.4
1.7
—
—
—
0
0
5
29
1.74
0.64
1.4
1.1
—
—
—
0
0
174
1696
1.78
0.64
28.8
24.5
134.16
136.52
g/l
1.70
174
1683
8
52
1.56
0.60
1.3
1.6
—
6.40
—
0
11
64
561
1.22
0.58
6.8
5.3
2.93
1.82
ug/l
0.50
55
505
18
133
1.39
0.57
1.8
1.9
3.52
3.60
mmol/l
0.12
11
98
48
409
1.24
0.57
1.3
1.3
0.57
1.22
u/ml
—
9
119
28
226
1.28
0.52
1.1
1.2
—
—
—
0
0
18
136
1.36
0.51
1.6
2.9
0.30
0.29
e6/l
0.03
18
131
9
65
1.40
0.51
1.0
1.2
—
—
—
0
0
34
283
1.25
0.50
1.3
1.3
1.47
5.39
u/ml
—
10
114
166
1612
1.38
0.50
13.8
13.6
—
—
—
0
0
155
1495
1.26
0.46
4.9
4.3
1.23
1.31
mmol/l
1.02
138
1388
41
473
0.83
0.45
2.0
3.0
0.00
0.00
estimate
—
7
158
40
462
0.83
0.45
3.6
4.1
0.00
0.00
estimate
—
8
180
37
315
1.22
0.45
1.4
1.3
60.57
26.36
iu/ml
—
7
102
5
31
1.63
0.43
2.4
3.4
15.00
43.13
u/ml
—
5
31
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
18.1
—
1714.07
—
0
15
128
1333
0.86
0.35
25.6
20.1
13.55
13.57
%
0.06
128
1327
23
192
1.23
0.34
1.7
1.4
—
—
—
0
0
59
538
1.14
0.33
3.7
3.6
2.33
2.35
mmol/l
0.49
48
494
15
186
0.79
0.33
1.4
1.6
—
—
—
0
0
7
54
1.31
0.31
1.3
1.2
—
101.25
—
0
8
23
195
1.21
0.30
1.2
1.4
—
—
—
0
0
48
436
1.14
0.28
1.3
1.4
—
—
—
0
0
28
244
1.17
0.28
1.7
2.0
—
—
—
0
0
66
705
0.90
0.25
2.1
1.9
1.45
1.39
mmol/l
0.19
53
595
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
11.1
—
0.68
—
0
13
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
5
66
0.75
0.17
1.0
1.1
—
—
—
0
0
5
69
0.72
0.17
2.8
3.0
1.42
1.48
%
—
5
63
21
187
1.14
0.16
2.1
1.9
307.81
391.91
nmol/l
1.44
21
175
76
728
1.08
0.15
2.6
2.6
—
—
estimate
—
0
0
148
1504
0.91
0.14
5.2
5.0
5.97
5.94
mmol/l
0.07
131
1396
27
248
1.10
0.13
1.4
1.7
774.11
1178.90
nmol/l
2.09
18
190
9
105
0.85
0.13
1.6
1.2
—
—
—
0
0
52
546
0.93
0.12
3.3
4.0
5.01
9.19
mg/mmol
1.13
31
344
158
1560
1.10
0.12
5.9
5.1
4.77
4.64
mmol/l
0.94
143
1470
51
532
0.94
0.10
3.1
3.3
42.68
54.36
mg/l
0.30
31
348
157
1554
1.08
0.08
5.7
5.1
1.48
1.44
mmol/l
0.64
142
1455
8
76
1.06
0.07
3.5
3.6
—
—
—
0
0
9
83
1.09
0.07
1.3
1.7
—
—
—
0
0
9
87
1.04
0.07
2.6
4.7
—
—
—
0
0
37
357
1.05
0.05
3.0
4.0
1.01
1.02
kg/l
1.68
26
237
58
566
1.04
0.05
2.8
3.2
7.96
8.07
mmol/l
0.06
45
475
147
1476
0.98
0.00
6.4
6.3
38.84
39.38
mmol/mol
0.29
136
1409
20
197
1.02
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
2.16
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
2140.00
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
158
1580
1.00
-0.00
6.4
5.8
2.85
2.73
mmol/l
0.94
141
1485
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
59
1.02
-0.00
5.7
3.1
1.00
0.85
%
—
6
53
0
8
0.00
-0.00
0.0
1.1
—
183.00
—
0
8
0
9
0.00
-0.00
0.0
1.2
—
73.89
—
0
9
6
63
0.95
-0.00
4.2
3.4
1485.33
1162.41
u/ml
—
6
54
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
95
0.94
-0.00
1.2
1.2
—
123.09
—
0
34
0
6
0.00
-0.00
0.0
2.7
—
4.22
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
38.14
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
13.00
—
0
9

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_TICK_BORNE_ENCEPHALITIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_TICK_BORNE_ENCEPHALITIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: AB1_TICK_BORNE_ENCEPHALITIS – Tick-borne viral encephalitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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