Meckel's diverticulum

Q17_MECKELS_DIVERTICULUM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q43.0
  • Hospital discharge: ICD-9 7510A|7510B
  • Cause of death: ICD-10 Q43.0
  • Cause of death: ICD-9 7510A|7510B

2 out of 7 registries used, show all original rules.

255

4. Check minimum number of events

None

255

5. Include endpoints

None

255

6. Filter based on genotype QC (FinnGen only)

223

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 223 103 120
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 45.19 43.93 46.27

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
232
Matched controls
2320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q43.0
ICD-10 Finland
Meckel diverticulum
+∞
212.5
170
*
JFB00
NOMESCO Finland
Partial resection of small intestine
49.1
73.7
44
11
7510A
ICD-9 Finland
Other congenital anomalies of digestive system, Meckel's diverticulum[DIVERTICULUM MECKELI]
+∞
64.7
59
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
+∞
42.0
39
*
JEA00
NOMESCO Finland
Appendectomy
9.0
38.2
54
76
6421
FHL
Appendicectomy
10.6
36.7
44
50
6401
FHL
Enterotomy and any possible small procedure related to it, eg removal of a foreign object, diverticulum or polyps
+∞
32.0
30
*
JAH01
NOMESCO Finland
Laparoscopy
8.5
21.8
30
40
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.6
20.9
127
581
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.2
18.6
26
35
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.8
18.4
48
120
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
15.0
13.5
22
16
UJF32
NOMESCO Finland
Coloscopy
2.8
11.4
78
358
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
8.9
10.6
22
27
6402
FHL
Small bowel resection
+∞
10.5
10
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.4
9.8
20
40
JFA74
NOMESCO Finland
Laparoscopic excision of lesion of small intestine
+∞
9.4
9
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
9.0
89
479
P01AB01
ATC
metronidazole; oral, rectal
2.3
8.8
109
645
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
8.6
44
170
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
3.4
7.9
31
102
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.9
74
386
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
7.8
63
306
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
7.8
50
218
JAH00
NOMESCO Finland
Laparotomy
7.0
7.3
17
26
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
20.8
7.2
10
5
5409X
ICD-9 Finland
Acute appendicitis, Without mention of peritonitis
4.6
7.1
17
39
K50.0
ICD-10 Finland
Crohn disease of small intestine
9.1
6.6
13
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
6.4
73
407

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
283
2.34
6.67
3.5
2.7
208.26
121.87
ug/g
0.30
51
234
51
252
2.31
5.99
1.3
1.3
—
—
—
0
0
48
245
2.21
5.18
1.5
1.4
—
—
—
0
0
85
542
1.90
4.96
4.6
4.5
—
—
—
0
0
188
1547
2.13
4.95
10.0
8.3
76.36
77.80
u/l
0.26
179
1473
145
1100
1.85
4.80
7.4
6.7
10.42
11.58
umol/l
1.00
139
1056
122
883
1.80
4.66
6.1
4.9
35.45
36.27
g/l
0.82
115
846
102
702
1.81
4.59
5.8
6.0
—
—
—
0
0
132
988
1.78
4.42
7.3
8.0
1.21
1.21
mmol/l
0.11
111
864
151
1181
1.80
4.30
11.1
10.6
4.84
4.10
e9/l
2.22
131
1032
117
851
1.76
4.28
2.3
2.1
91.65
96.52
pmol/l
0.47
69
453
116
861
1.69
3.80
3.3
3.3
6.34
6.18
ph
0.77
69
492
86
593
1.72
3.67
4.1
3.0
0.35
0.33
e6/l
0.05
68
426
63
403
1.77
3.48
5.0
3.6
111.76
233.31
ng/l
0.49
45
301
74
496
1.72
3.47
2.9
2.3
2.54
2.78
mg/l
0.52
69
444
148
1190
1.67
3.44
5.8
5.5
6.56
6.65
mmol/l
0.27
142
1129
11
27
4.22
3.44
1.6
1.6
24.75
33.02
ng/l
0.26
11
27
117
887
1.64
3.42
11.3
11.8
1.24
1.22
inr
0.21
98
725
174
1466
1.75
3.34
3.9
3.4
38.26
48.75
u/l
2.57
163
1407
67
443
1.72
3.28
1.8
1.8
0.86
1.30
mg/l
0.89
54
354
93
677
1.62
3.13
4.9
3.2
66.06
144.22
e6/l
0.32
74
508
90
653
1.62
3.06
3.0
2.5
—
—
—
0
0
102
766
1.59
2.99
5.5
3.9
48.11
105.06
e6/l
0.63
78
533
117
911
1.57
2.92
11.5
11.2
0.00
0.00
e9/l
1.13
94
743
13
47
2.87
2.86
2.3
2.4
176.70
135.05
ug/min
—
8
25
123
973
1.56
2.83
7.2
6.4
8.42
8.70
%
0.54
115
929
123
974
1.56
2.81
7.1
6.2
2.49
2.81
%
1.14
115
926
59
392
1.68
2.80
2.5
2.9
543.47
560.10
mosm/kgh2o
0.23
53
340
216
1986
2.27
2.66
22.4
15.3
28.21
23.48
mg/l
1.28
192
1622
72
512
1.59
2.59
3.2
3.0
—
—
—
0
0
117
928
1.53
2.58
3.3
2.9
—
—
estimate
—
0
0
18
83
2.27
2.48
1.0
1.2
—
—
—
0
0
123
994
1.51
2.44
7.2
6.3
26.57
27.43
%
0.39
117
957
121
979
1.49
2.36
7.2
6.2
58.73
57.48
%
0.51
115
943
120
970
1.49
2.35
7.4
6.4
0.58
0.68
%
1.30
112
914
129
1061
1.49
2.30
3.8
3.6
0.00
0.00
estimate
-0.00
27
201
131
1081
1.49
2.29
7.0
6.4
1.86
1.88
e9/l
0.09
115
952
130
1072
1.48
2.28
3.8
3.6
0.00
0.00
estimate
-0.00
26
204
216
2005
2.12
2.27
24.4
17.9
3.97
3.97
mmol/l
0.04
211
1970
112
899
1.48
2.24
7.3
7.2
1.21
1.21
mmol/l
0.13
99
839
172
1506
1.55
2.23
4.6
4.1
14.61
14.68
pmol/l
0.15
162
1388
52
354
1.60
2.22
4.4
3.8
0.80
0.82
mmol/l
0.68
47
338
80
602
1.50
2.19
2.8
2.8
—
0.22
—
0
9
215
2003
2.00
2.06
24.3
17.8
139.53
139.73
mmol/l
0.52
210
1971
127
1058
1.44
2.02
7.1
6.3
0.58
0.57
e9/l
0.20
112
911
127
1059
1.44
2.00
7.1
6.3
0.04
0.04
e9/l
0.16
112
909
37
238
1.66
1.97
6.5
10.9
0.38
0.82
mmol/l
0.21
28
201
131
1101
1.44
1.97
7.6
6.8
0.18
0.19
e9/l
0.30
115
967
129
1082
1.43
1.95
3.9
3.7
0.00
0.00
estimate
-0.00
28
187
98
784
1.43
1.92
2.6
2.0
—
—
—
0
0
22
123
1.87
1.87
4.8
3.6
7.38
7.42
ph
0.78
14
105
17
88
2.01
1.80
5.4
3.8
—
—
—
0
0
49
348
1.52
1.74
4.1
3.0
1.31
1.66
e6/l
0.26
24
171
36
240
1.59
1.68
6.9
10.9
7.41
7.42
ph
0.42
19
130
80
630
1.41
1.67
7.1
6.5
—
—
—
0
0
32
208
1.62
1.65
4.0
3.7
1.29
1.46
mmol/l
0.11
26
178
37
250
1.57
1.63
1.5
1.2
—
—
—
0
0
62
475
1.42
1.49
1.5
1.4
2.11
2.41
g/l
0.73
34
303
7
28
2.55
1.46
6.4
3.9
2.14
3.44
nmol/l
—
7
28
98
814
1.35
1.44
3.5
3.5
0.00
0.02
estimate
0.50
21
178
5
16
3.17
1.44
1.0
1.1
—
—
—
0
0
32
216
1.56
1.43
4.1
3.7
7.36
7.39
ph
1.05
14
117
112
951
1.34
1.42
4.2
3.1
131.44
123.01
ug/l
0.11
101
903
41
293
1.49
1.41
2.0
2.1
—
—
—
0
0
62
483
1.39
1.35
3.4
3.5
—
0.33
—
0
6
6
24
2.54
1.31
1.5
1.4
—
—
—
0
0
14
77
1.87
1.28
2.1
1.9
—
—
—
0
0
195
1823
1.44
1.21
5.8
5.0
1.70
1.87
mu/l
1.94
183
1688
12
64
1.92
1.20
3.7
1.7
281.40
742.49
u/l
—
5
15
50
383
1.39
1.20
1.8
1.8
362.71
35347882.27
pmol/l
0.50
41
331
8
38
2.14
1.19
1.1
1.1
—
—
—
0
0
60
475
1.35
1.18
4.6
4.9
—
—
—
0
0
7
31
2.30
1.11
2.0
3.1
5.90
4.87
e9/l
—
7
31
5
21
2.41
1.09
1.2
1.1
—
—
—
0
0
23
154
1.55
1.08
4.1
3.2
—
—
—
0
0
65
528
1.32
1.07
1.4
1.3
5.27
1.49
u/ml
0.59
15
151
26
182
1.48
1.01
2.5
3.0
72.79
71.54
e9/l
0.06
18
133
13
76
1.75
1.01
1.1
1.4
—
—
—
0
0
75
627
1.29
1.00
4.4
4.0
7.40
7.39
ph
0.20
50
447
5
23
2.20
0.98
1.0
1.3
—
—
—
0
0
7
36
1.97
0.98
1.0
1.3
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
7
37
1.92
0.95
1.3
1.4
—
—
—
0
0
12
70
1.75
0.94
1.2
1.2
—
—
—
0
0
26
186
1.45
0.92
1.7
1.5
—
—
—
0
0
48
382
1.32
0.91
3.2
2.9
2.43
2.44
mmol/l
0.57
43
348
28
204
1.42
0.90
9.9
9.4
—
—
—
0
0
59
485
1.29
0.89
3.9
3.7
1.01
1.02
kg/l
1.96
40
321
24
171
1.45
0.87
1.6
1.4
—
—
—
0
0
6
31
1.96
0.85
1.5
1.1
—
—
—
0
0
17
113
1.54
0.85
1.2
1.2
—
—
—
0
0
18
123
1.50
0.80
2.7
7.9
—
—
—
0
0
5
98
0.50
0.80
1.0
1.1
—
—
—
0
0
81
701
1.24
0.80
3.8
3.2
8.87
7.97
mmol/l
0.77
70
596
37
290
1.33
0.79
7.0
7.8
105.65
104.23
mmol/l
1.19
37
290
67
570
1.25
0.77
2.0
1.7
21.46
21.12
nmol/l
0.06
58
491
26
194
1.38
0.75
1.2
1.2
—
—
—
0
0
21
151
1.43
0.74
5.0
4.6
7.38
7.36
ph
0.70
16
110
10
60
1.70
0.73
1.2
1.2
—
—
—
0
0
10
60
1.70
0.73
1.2
1.4
381.00
283.60
ug/g
—
5
34
7
39
1.82
0.73
1.7
1.6
—
—
—
0
0
38
303
1.30
0.73
1.7
1.4
600.00
510.63
titre
—
6
64
223
2176
1.64
0.72
33.1
23.3
6.94
6.66
e9/l
1.44
218
2141
223
2176
1.64
0.72
32.9
23.2
4.57
4.57
e12/l
0.03
217
2140
223
2174
1.66
0.72
33.2
23.2
257.56
247.59
e9/l
1.71
218
2143
217
2106
1.47
0.70
14.8
11.6
27.92
27.73
u/l
0.03
211
2056
38
307
1.28
0.66
1.8
1.7
1161.65
1179.54
nmol/l
0.04
26
235
68
591
1.21
0.63
1.5
1.5
—
—
—
0
0
65
564
1.21
0.62
4.0
3.7
0.00
0.02
estimate
0.74
25
190
8
51
1.59
0.61
1.4
1.5
—
—
—
0
0
72
632
1.20
0.61
4.1
3.4
59.03
58.97
mg/l
0.00
48
419
17
123
1.41
0.60
1.6
2.7
0.54
0.62
%
0.77
17
123
29
231
1.29
0.57
1.7
1.5
—
—
—
0
0
84
752
1.18
0.57
4.0
3.7
20.94
37.05
ng/l
1.33
50
517
73
646
1.19
0.56
4.7
4.0
10.13
9.51
mg/mmol
0.03
44
413
9
59
1.55
0.55
1.2
1.1
—
—
—
0
0
12
82
1.49
0.55
1.1
1.1
0.95
0.88
g/l
0.38
12
82
6
38
1.59
0.54
2.2
2.5
—
—
—
0
0
212
2062
1.33
0.54
16.9
13.4
—
—
—
0
0
69
612
1.18
0.52
3.5
3.1
0.00
0.01
estimate
0.50
21
163
11
75
1.49
0.51
2.5
1.6
—
—
—
0
0
19
244
0.76
0.50
1.2
1.4
—
—
—
0
0
7
47
1.50
0.48
2.0
2.5
67.86
61.00
%
—
7
47
32
265
1.24
0.48
1.3
1.5
—
—
—
0
0
41
349
1.21
0.48
1.4
1.3
5.69
5.87
u/ml
—
10
127
26
211
1.26
0.46
1.9
1.7
—
—
—
0
0
35
295
1.22
0.45
1.7
1.5
—
—
—
0
0
29
240
1.24
0.44
1.6
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
195.11
—
0
15
0
17
0.00
0.41
0.0
1.2
—
6.93
—
0
17
5
35
1.44
0.39
1.4
1.2
—
—
—
0
0
9
68
1.34
0.38
2.6
2.3
—
—
—
0
0
43
377
1.17
0.37
1.8
1.6
—
—
—
0
0
11
81
1.38
0.37
1.0
1.1
1.40
1.54
g/l
0.84
11
81
16
126
1.29
0.36
1.7
1.4
0.16
0.35
mg/l
—
6
51
18
145
1.26
0.35
3.3
4.3
1.40
0.70
%
—
5
45
192
1964
0.87
0.30
5.1
4.9
1.38
1.42
mmol/l
0.86
182
1843
193
1973
0.87
0.29
5.3
5.0
4.54
4.61
mmol/l
0.50
182
1862
8
66
1.22
0.27
1.0
1.2
—
—
—
0
0
10
79
1.28
0.22
1.0
1.1
—
0.68
—
0
10
15
126
1.20
0.21
1.3
1.3
—
30.80
—
0
6
0
11
0.00
0.21
0.0
1.5
—
7.91
—
0
11
0
10
0.00
0.21
0.0
1.0
—
1654.00
—
0
10
0
10
0.00
0.21
0.0
1.5
—
10.80
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
79
750
1.08
0.19
5.1
5.2
2.00
1.88
ug/l
0.12
72
676
6
53
1.14
0.19
3.8
1.6
—
—
—
0
0
6
53
1.14
0.19
7.8
3.0
2.50
3.01
index
—
6
31
17
147
1.17
0.18
3.1
3.5
1.23
1.23
mmol/l
0.15
11
127
5
67
0.74
0.17
1.0
1.1
—
—
—
0
0
15
130
1.16
0.16
2.1
2.6
—
—
—
0
0
91
878
1.06
0.14
1.9
2.0
1.32
1.39
mmol/l
0.45
77
746
11
94
1.18
0.13
2.5
1.5
—
—
—
0
0
188
1858
1.06
0.10
7.7
6.1
39.34
39.16
mmol/mol
0.10
180
1765
82
845
0.95
0.10
3.6
3.0
—
—
—
0
0
48
459
1.06
0.09
2.1
1.9
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
191
1890
1.06
0.09
5.4
4.9
5.97
5.92
mmol/l
0.18
176
1762
7
81
0.86
0.07
1.4
1.9
212.00
246.05
pmol/l
—
7
76
29
275
1.06
0.07
1.3
1.5
—
—
—
0
0
47
453
1.05
0.07
2.8
3.0
0.77
0.75
ug/l
0.06
29
273
199
2002
0.96
0.04
5.9
5.6
2.67
2.73
mmol/l
0.42
186
1886
10
109
0.91
0.04
1.7
1.8
—
—
—
0
0
188
1869
1.03
0.03
4.4
4.2
1.29
1.29
mmol/l
0.01
175
1743
10
92
1.09
0.03
2.4
2.2
—
—
—
0
0
11
117
0.94
0.02
2.6
1.4
—
—
—
0
0
12
114
1.06
0.01
2.5
1.4
—
—
—
0
0
52
522
1.00
0.00
3.9
2.7
323.63
353.32
umol/l
1.27
46
459
13
133
0.98
0.00
1.2
1.2
—
—
—
0
0
39
393
0.99
0.00
1.3
1.3
33.41
30.03
iu/ml
—
8
123
12
116
1.04
0.00
2.5
1.4
—
—
—
0
0
12
116
1.04
0.00
2.5
1.4
—
—
—
0
0
17
166
1.03
0.00
6.1
2.9
0.72
0.20
e6/l
0.40
17
159
22
224
0.98
0.00
1.8
1.8
—
—
—
0
0
17
175
0.97
0.00
1.8
1.8
3.85
3.63
mmol/l
0.31
12
132
8
80
1.00
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
0.61
—
0
6
7
76
0.92
-0.00
1.9
1.3
—
84.55
—
0
11
12
120
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.6
1.48
1.15
g/l
—
6
65
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
-0.00
2.8
2.0
—
—
—
0
0
6
65
0.92
-0.00
8.0
10.6
—
—
—
0
0
7
76
0.92
-0.00
2.0
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.6
0.27
0.23
g/l
—
6
64
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
11
110
1.00
-0.00
2.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
58.67
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
58.50
—
0
6
5
53
0.94
-0.00
1.6
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_MECKELS_DIVERTICULUM – Meckel's diverticulum

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).