No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
137 |
4. Check minimum number of eventsNone |
137 |
5. Include endpointsNone |
137 |
6. Filter based on genotype QC (FinnGen only) |
117 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D15
- Name in latin
- Neoplasma benignum mediastini
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Mediastinum
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and unspecified intrathoracic organs
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 865 | 500 | 354 |
| Only index persons | 693 | 417 | 276 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 47.33 | 49.66 | 43.59 |
| Only index persons | 43.93 | 47.08 | 39.17 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 117 | 70 | 47 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 50.58 | 50.52 | 50.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 126
- Matched controls
- 1260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
118.0
94
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
178.1
27.9
28
*
21250
ICD-8 Finland
Benign neoplasm of respiratory system, Mediastinum
+∞
24.8
23
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.5
24.4
45
87
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
+∞
20.4
19
*
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
+∞
17.1
16
*
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
12.7
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
10.8
87
475
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
10.7
41
139
2125A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Mediastinum
+∞
10.6
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.3
10.1
69
336
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
8.6
52
232
WX402
NOMESCO Finland
General anaesthesia
3.1
7.9
45
192
R4110
NOMESCO Finland
Physiotherapy
2.9
7.6
53
253
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
4.3
7.1
20
53
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
+∞
6.3
6
*
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
98
575
4.17
10.95
7.6
8.4
1.19
1.21
mmol/l
1.35
90
499
33
106
3.86
9.19
7.3
10.1
1.21
1.31
mmol/l
0.17
33
106
36
131
3.45
8.26
7.7
9.2
5.23
5.18
kpa
0.14
36
126
58
297
2.77
7.18
3.1
2.6
—
—
—
0
0
25
86
3.38
6.15
7.5
8.9
24.11
24.83
mmol/l
0.37
25
86
81
546
2.35
4.99
3.2
2.9
—
—
estimate
—
0
0
77
512
2.30
4.84
6.1
5.0
36.18
35.82
g/l
0.20
72
485
27
130
2.37
3.51
2.4
4.9
1.29
1.78
mmol/l
0.22
20
111
40
231
2.07
3.34
3.6
3.4
72.32
116.07
ng/l
0.31
31
188
89
685
2.02
3.19
9.1
10.4
3.93
4.06
e9/l
0.21
68
598
72
516
1.92
3.19
3.6
3.0
113.39
109.84
ug/l
0.09
64
478
17
70
2.65
3.03
1.9
1.8
—
—
—
0
0
34
192
2.06
2.98
3.0
2.5
2.18
2.35
g/l
1.08
29
176
26
133
2.20
2.92
5.2
4.7
235.62
241.82
u/l
0.10
26
128
45
284
1.91
2.87
3.0
2.2
2.40
2.87
mg/l
0.66
34
251
25
127
2.21
2.85
2.9
4.9
2.41
10.94
ug/l
1.63
17
102
121
1093
3.70
2.81
22.8
16.5
23.30
22.11
mg/l
0.19
110
904
17
73
2.54
2.79
2.8
2.6
183.59
172.85
ng/l
0.04
17
65
18
80
2.46
2.76
2.1
4.5
23.41
24.43
mmol/l
0.64
18
80
102
855
2.01
2.47
5.7
4.5
12.21
12.03
mm/h
0.05
95
785
68
511
1.72
2.31
2.4
2.6
79.14
77.82
nmol/l
0.13
63
453
7
18
4.05
2.28
2.9
1.9
2.31
2.61
u/ml
—
7
18
104
910
1.82
1.77
27.5
20.6
14.00
13.62
%
1.63
104
905
5
13
3.96
1.73
1.2
1.4
—
—
—
0
0
5
13
3.96
1.73
1.0
1.3
—
—
—
0
0
50
369
1.59
1.69
2.9
2.6
52.42
68.43
u/l
0.67
45
340
5
15
3.42
1.54
2.0
2.0
11.48
17.15
ug/l
—
5
15
6
24
2.57
1.32
1.3
1.3
—
—
—
0
0
29
199
1.59
1.30
2.7
3.2
4.20
2.60
e6/l
—
10
96
8
36
2.30
1.27
1.0
1.5
—
—
—
0
0
28
192
1.59
1.26
2.1
1.9
—
—
—
0
0
113
1042
1.82
1.22
5.5
5.5
1.74
1.89
mu/l
0.79
107
954
8
39
2.12
1.17
2.8
1.5
—
—
—
0
0
43
341
1.40
0.95
3.4
3.2
0.17
0.40
e6/l
1.46
28
241
30
223
1.45
0.94
2.8
3.0
0.75
0.80
e6/l
0.04
12
118
6
28
2.20
0.93
1.2
1.4
—
—
—
0
0
6
30
2.05
0.88
1.7
1.4
—
—
—
0
0
20
140
1.51
0.83
2.3
1.9
—
—
—
0
0
11
66
1.73
0.81
5.8
3.3
4.03
4.61
pmol/l
2.21
11
59
18
124
1.53
0.80
2.3
3.4
—
—
—
0
0
15
100
1.57
0.77
1.7
1.5
—
—
—
0
0
39
472
0.75
0.75
3.8
3.8
0.00
0.01
estimate
0.50
11
104
7
38
1.89
0.75
1.3
1.8
—
—
—
0
0
7
39
1.84
0.74
1.3
1.9
—
—
—
0
0
7
40
1.79
0.72
1.3
2.4
—
—
—
0
0
7
41
1.75
0.71
1.6
1.6
—
0.01
—
0
6
10
61
1.69
0.71
2.8
4.8
24.30
25.02
mmol/l
—
10
61
45
377
1.30
0.67
3.7
3.4
698.86
1080.14
ng/l
1.25
36
303
12
79
1.57
0.65
1.8
1.5
—
—
—
0
0
5
30
1.69
0.62
1.4
1.3
—
—
—
0
0
41
343
1.29
0.61
2.0
1.7
22.68
21.49
nmol/l
0.23
34
279
113
1077
1.48
0.61
5.4
5.3
6.13
5.97
mmol/l
0.46
105
984
8
52
1.57
0.61
1.4
2.5
—
—
—
0
0
20
150
1.40
0.60
2.3
1.8
—
—
—
0
0
59
518
1.26
0.60
2.4
2.1
81.55
97.43
pmol/l
2.20
29
253
34
279
1.30
0.59
2.3
1.9
0.80
1.58
mg/l
1.58
28
222
6
35
1.75
0.58
1.7
1.2
—
—
—
0
0
93
866
1.28
0.55
4.5
4.5
14.61
15.02
pmol/l
0.90
86
792
6
38
1.61
0.55
1.3
1.2
—
—
—
0
0
27
217
1.31
0.54
1.3
1.3
106.07
35.76
iu/ml
—
9
70
55
484
1.24
0.53
1.9
2.1
1.37
1.36
mmol/l
0.02
47
403
25
199
1.32
0.53
1.9
1.6
1184.68
1182.70
nmol/l
0.00
19
149
9
65
1.41
0.52
3.4
2.3
31.44
43.04
u/l
—
9
57
24
191
1.32
0.51
1.2
1.3
0.81
7.40
u/ml
—
7
70
7
110
0.62
0.51
3.7
2.5
0.92
0.26
e6/l
—
7
105
5
31
1.64
0.43
2.6
1.2
42284.00
9986.27
e6/l
—
5
22
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
9
67
1.37
0.39
1.6
1.4
—
—
—
0
0
24
199
1.25
0.39
2.0
1.6
—
—
—
0
0
9
68
1.35
0.38
1.0
1.0
—
—
—
0
0
5
36
1.40
0.38
2.4
1.3
0.99
0.88
g/l
—
5
36
74
689
1.18
0.36
3.2
3.1
—
—
—
0
0
31
352
0.84
0.31
2.9
3.5
0.00
0.00
estimate
-0.00
12
96
30
340
0.85
0.29
4.4
3.6
0.00
0.00
estimate
-0.00
12
113
9
72
1.27
0.26
4.6
4.8
38.10
47.31
%
—
9
72
5
39
1.29
0.23
4.2
2.2
216.60
197.79
%
—
5
39
19
219
0.84
0.22
2.5
3.0
1.15
0.78
ug/l
0.32
12
137
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.24
0.20
3.0
1.7
258.00
380.37
ug/l
—
6
44
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
14
164
0.84
0.19
1.4
1.6
—
—
—
0
0
6
76
0.78
0.16
1.8
2.8
1.10
1.19
%
—
6
76
24
261
0.90
0.13
3.9
3.7
1.02
1.02
kg/l
0.25
14
172
106
1041
1.11
0.12
4.4
4.5
1.24
1.29
mmol/l
0.33
99
949
66
638
1.07
0.11
3.1
3.9
0.00
12.89
estimate
0.50
12
126
65
632
1.06
0.08
3.2
3.8
0.00
0.00
estimate
-0.00
12
126
66
644
1.05
0.07
3.1
3.9
0.00
0.00
estimate
-0.00
11
120
41
396
1.05
0.06
3.4
4.1
1.17
7.97
mg/mmol
3.85
27
249
48
467
1.04
0.05
4.2
3.9
27.50
44.77
ng/l
0.54
32
338
11
120
0.91
0.05
1.4
2.0
—
—
—
0
0
110
1091
1.06
0.03
5.3
5.3
1.40
1.48
mmol/l
1.07
103
999
12
112
1.08
0.03
1.3
1.8
—
—
—
0
0
112
1112
1.06
0.02
6.4
6.2
2.64
2.68
mmol/l
0.17
105
1019
109
1097
0.95
0.01
5.5
5.4
4.57
4.61
mmol/l
0.13
102
1010
13
134
0.97
0.00
12.1
7.2
—
—
—
0
0
28
283
0.99
0.00
4.8
4.8
23.81
22.57
%
—
10
140
15
152
0.99
0.00
4.1
5.3
32.10
31.64
%
—
10
94
0
7
0.00
-0.00
0.0
2.1
—
42.81
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
81
0.99
-0.00
1.8
4.3
4.80
5.04
kpa
—
8
81
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
62.86
—
0
7
0
5
0.00
-0.00
0.0
5.0
—
4.39
—
0
5
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
8.09
—
0
9
5
51
0.98
-0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1860.33
—
0
6
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.30
—
0
7
0
5
0.00
-0.00
0.0
5.0
—
10.20
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
14.00
—
0
5
0
6
0.00
-0.00
0.0
3.2
—
1.33
—
0
6
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
49
1.02
-0.00
4.4
2.3
0.00
0.00
g/l
—
5
49
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
5.11
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MEDIASTINUM and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MEDIASTINUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MEDIASTINUM – Benign neoplasm: Mediastinum
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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