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Benign neoplasm of other and unspecified intrathoracic organs

DOID Endpoint Browser PheWeb

CD2_BENIGN_INTRATHORACIC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D15
  • Cause of death: ICD-10 — D15

2 out of 7 registries used, show all original rules.

386

4. Check minimum number of events

None

386

5. Include endpoints

446

6. Filter based on genotype QC (FinnGen only)

383

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum endothoracicorum aliorum sive non specificatorum

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2498 1388 1085
Only index persons 2049 1198 851
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 54.47 56.23 51.98
Only index persons 52.89 55.50 49.23

-FinnGen-

Key figures

All Female Male
Number of individuals 383 208 175
Unadjusted period prevalence (%) 0.08 0.07 0.08
Median age at first event (years) 58.23 57.63 58.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
405
Matched controls
4050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.1
ICD-10 Finland
Benign neoplasm: Heart
+∞
136.4
123
*
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
102.6
94
*
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
91.2
84
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
75.4
70
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
247.8
63.1
63
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.0
54.0
118
259
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
51.8
157
456
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
526.9
48.4
47
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.8
44.9
79
139
D15.9
ICD-10 Finland
Benign neoplasm: Intrathoracic organ, unspecified
+∞
42.4
40
*
D15.7
ICD-10 Finland
Benign neoplasm: Other specified intrathoracic organs
+∞
40.3
38
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
8.4
40.0
56
76
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
32.3
281
1560
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
277.4
26.0
26
*
21250
ICD-8 Finland
Benign neoplasm of respiratory system, Mediastinum
+∞
24.2
23
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
254.4
23.9
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
22.0
152
700
WX872
NOMESCO Finland
Intensive care
5.1
21.9
49
106
GEC23
NOMESCO Finland
Transsternal thymectomy
232.0
21.8
22
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.6
20.1
52
127
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
17.8
17
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
16.2
114
519
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
25.7
16.2
22
9
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
15.7
189
1098
R4110
NOMESCO Finland
Physiotherapy
2.4
15.6
152
805
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.5
14.7
129
648
GD1AD
NOMESCO Finland
Thorax CT examination
3.6
14.6
51
154
WX402
NOMESCO Finland
General anaesthesia
2.5
14.4
120
588
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
13.6
13
*
B01AB05
ATC
enoxaparin; parenteral
2.2
13.2
160
916
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
13.2
44
129
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
12.6
12
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
12.4
69
276
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
48.2
11.9
14
*
AJX
HP
Other surgery on the heart or aorta
66.9
11.7
13
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
11.5
11
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
11.5
51
179
ZXC96
NOMESCO Finland
Robot assisted procedure
5.4
11.4
23
45
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
11.3
129
714
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
10.8
65
269
2125A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Mediastinum
+∞
10.5
10
*
B01AB04
ATC
dalteparin; parenteral
3.8
10.4
33
93
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
10.2
46
163
G70.0
ICD-10 Finland
Myasthenia gravis
26.8
9.9
13
5
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
4.6
9.7
23
52
C03CA01
ATC
furosemide; systemic
2.0
9.5
146
893
N07AA02
ATC
pyridostigmine; systemic
18.1
9.5
14
8
AMX
HP
Other surgical procedure for a demanding cardiac patient
102.3
9.5
10
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.4
9.3
34
106
WZC30
NOMESCO Finland
Teaching
2.2
9.0
87
446
N02AX02
ATC
tramadol; systemic, rectal
1.9
8.6
195
1346
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
8.6
98
536
GAA31
NOMESCO Finland
Thoracoscopy
91.9
8.4
9
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.3
8.3
32
103
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
8.3
135
836
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.5
8.2
29
88
R06.0
ICD-10 Finland
Dyspnoea
1.9
8.1
130
800
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
45.9
7.7
9
*
108
Kela drug reimbursment
Myasthenia gravis
25.6
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
7.4
157
1050
I31.8
ICD-10 Finland
Other specified diseases of pericardium
+∞
7.3
7
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
7.0
69
355
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
6.9
119
745
WF003
NOMESCO Finland
Adjuvant radiotherapy
3.8
6.8
21
58
A02BC02
ATC
pantoprazole; systemic
1.8
6.8
287
2318
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
40.8
6.8
8
*
B01AA03
ATC
warfarin; systemic
2.0
6.8
85
478
GEA00
NOMESCO Finland
Mediastinoscopy
23.0
6.7
9
*
ZXE00
NOMESCO Finland
One hour or less
1.7
6.5
159
1098
51
HP
Other heart surgery
70.9
6.4
7
*
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
70.9
6.4
7
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.9
6.4
19
51
21240
ICD-8 Finland
Benign neoplasm of respiratory system, Pleura
+∞
6.3
6
*
2129X
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Site unspecified
+∞
6.3
6
*
R81
ICPC
Pneumonia
3.4
6.2
22
67
AN1
HP
Coronary angiography
2.2
6.1
52
251
WX892
NOMESCO Finland
Monitored bed care
2.5
6.1
39
166
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
6.2
6.1
15
25
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.9
6.0
28
101

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
287
1766
3.15
24.79
17.2
13.0
1.24
1.24
inr
0.04
238
1447
213
1203
2.63
20.16
2.8
2.4
—
—
—
0
0
269
1702
2.73
20.15
3.0
2.8
—
—
estimate
—
0
0
176
907
2.66
20.10
2.6
2.3
—
—
—
0
0
110
445
3.02
19.93
10.9
7.8
0.87
0.78
mmol/l
0.08
99
372
111
458
2.96
19.35
11.0
7.6
5.32
5.11
kpa
1.33
111
440
284
1877
2.72
18.95
9.6
7.2
1.20
1.21
mmol/l
3.04
255
1628
109
453
2.92
18.69
11.0
7.7
7.42
7.41
ph
0.51
48
262
260
1689
2.51
17.28
10.6
6.4
1.19
1.21
mmol/l
3.63
247
1551
75
264
3.26
17.04
12.5
9.5
1.17
1.35
%
1.10
75
259
66
215
3.47
16.97
11.7
8.9
15.61
15.65
%
0.04
66
208
74
260
3.26
16.86
12.8
9.7
0.62
0.66
%
0.39
74
255
181
1033
2.36
15.65
4.8
4.3
—
—
—
0
0
86
344
2.90
15.58
10.9
8.7
—
—
—
0
0
85
339
2.91
15.48
1.4
1.4
—
—
—
0
0
303
2175
2.56
15.26
8.5
5.0
6.60
6.70
mmol/l
0.44
297
2068
163
955
2.18
12.59
3.1
2.1
3.01
3.01
mg/l
0.00
144
825
347
2781
2.73
11.84
10.5
8.4
81.74
79.55
u/l
0.51
337
2633
62
240
2.87
11.77
11.7
9.7
24.06
24.26
mmol/l
0.22
62
235
100
491
2.38
11.69
1.4
1.3
—
—
—
0
0
183
1147
2.09
11.64
5.0
4.1
7.40
7.40
ph
0.48
130
806
245
1719
2.08
11.35
7.6
6.5
9.16
8.90
%
0.68
237
1623
244
1717
2.06
11.13
7.6
6.4
0.69
0.68
%
0.14
236
1609
235
1636
2.04
10.98
6.3
5.1
35.54
35.71
g/l
0.17
222
1547
246
1746
2.04
10.83
7.7
6.4
26.25
27.43
%
1.01
239
1658
243
1721
2.03
10.72
7.6
6.3
2.67
2.88
%
0.79
235
1617
259
1897
2.01
10.15
7.5
6.2
1.74
1.97
e9/l
2.02
220
1665
185
1210
1.97
10.04
3.9
3.3
903.35
1295.90
ng/l
1.80
165
1011
255
1867
1.99
9.89
7.5
6.2
0.59
0.59
e9/l
0.06
211
1594
255
1871
1.98
9.78
7.4
6.2
0.04
0.04
e9/l
0.86
211
1599
275
2074
2.02
9.70
11.7
10.1
4.09
4.10
e9/l
0.03
228
1815
259
1924
1.96
9.41
8.0
6.5
0.16
0.19
e9/l
3.49
219
1667
107
586
2.12
9.40
3.2
2.4
2.29
2.31
g/l
0.17
98
545
186
1245
1.91
9.20
3.4
3.4
29.24
31.34
u/l
0.34
181
1173
204
1438
1.84
8.33
2.3
2.1
—
—
—
0
0
108
630
1.97
7.83
3.3
2.4
11.95
13.16
umol/l
0.85
100
590
85
458
2.08
7.66
3.5
2.7
1.76
1.78
%
0.09
78
414
172
1175
1.81
7.58
2.4
2.1
175.42
210.57
u/l
0.65
167
1115
97
551
2.00
7.56
3.2
2.4
19.01
22.59
%
2.20
91
521
257
1982
1.81
7.47
8.6
6.8
11.09
11.43
umol/l
0.27
247
1894
74
383
2.14
7.39
4.9
3.7
2.09
1.83
mmol/l
0.22
62
321
222
1648
1.77
7.27
3.9
3.0
124.96
126.87
ug/l
0.04
207
1530
74
397
2.06
6.70
5.1
3.7
7.38
7.38
ph
0.70
44
239
118
750
1.81
6.42
4.3
4.1
354.17
349.61
ng/l
0.01
99
606
50
235
2.29
6.30
14.5
6.8
25.71
24.43
mmol/l
1.61
50
223
19
52
3.78
6.27
3.0
2.6
—
—
—
0
0
158
1100
1.72
6.23
8.0
6.6
—
—
—
0
0
24
81
3.09
5.79
2.0
2.3
126.47
126.98
g/l
0.03
15
59
211
1628
1.62
5.34
16.0
11.4
0.00
0.00
e9/l
0.06
164
1326
154
1106
1.63
5.18
4.1
3.3
—
—
—
0
0
184
1386
1.60
5.06
4.5
3.9
120.21
90.90
e6/l
0.17
130
986
291
2450
1.67
5.02
5.3
4.7
—
2.71
—
0
5
72
423
1.85
4.95
3.1
3.0
7.07
8.66
umol/l
0.34
62
381
71
422
1.83
4.70
3.2
4.4
3.70
41.69
ug/l
1.27
56
354
48
250
2.04
4.68
2.3
1.6
0.96
1.29
g/l
1.18
39
228
171
1284
1.57
4.67
4.1
3.5
2.34
2.36
mmol/l
0.51
158
1168
7
5
14.21
4.59
13.4
8.8
6.06
5.90
kpa
—
7
5
7
5
14.21
4.59
11.4
8.6
5.19
4.94
kpa
—
7
5
93
605
1.70
4.51
3.3
3.0
3.90
1.90
e6/l
0.77
43
307
145
1060
1.57
4.39
3.9
3.2
0.42
0.48
e6/l
0.16
104
777
34
159
2.24
4.35
2.3
1.8
1.80
1.45
g/l
0.96
28
144
55
310
1.90
4.29
3.7
2.9
10.76
10.64
g/l
0.05
49
288
118
826
1.60
4.27
2.5
1.7
1.17
1.30
mg/l
0.21
99
663
186
1455
1.51
4.06
5.4
4.0
40.97
36.88
ng/l
0.19
135
1077
60
359
1.79
3.88
3.3
2.7
76.14
69.48
e9/l
0.60
35
268
45
249
1.91
3.72
4.1
3.7
7.42
7.42
ph
0.20
38
208
370
3415
1.97
3.67
26.4
16.5
24.36
23.55
mg/l
0.23
345
2823
82
545
1.63
3.62
1.7
1.8
—
—
—
0
0
18
68
2.72
3.61
4.3
3.1
—
—
—
0
0
7
9
7.89
3.57
1.9
1.8
50.14
27.11
%
—
7
9
25
113
2.29
3.49
3.2
4.2
7.95
2.39
ratio
0.45
16
63
159
1233
1.48
3.49
4.0
3.3
22.16
108.23
e6/l
0.97
119
945
133
997
1.50
3.44
4.0
3.1
—
0.00
estimate
—
0
5
26
122
2.21
3.34
3.3
4.5
135.35
97.56
mg/l
0.20
21
106
199
1623
1.44
3.31
2.8
2.5
77.41
78.21
nmol/l
0.15
181
1443
103
737
1.53
3.30
3.0
3.0
521.09
530.97
mosm/kgh2o
0.20
89
642
44
254
1.82
3.21
2.9
2.9
—
—
—
0
0
13
40
3.32
3.17
1.2
1.1
—
—
—
0
0
28
140
2.07
3.08
2.9
2.2
10.41
10.75
g/l
0.12
28
126
7
12
5.91
3.03
1.3
1.4
56.86
56.50
nmol/24h
—
7
12
17
69
2.53
3.00
1.7
1.8
—
—
—
0
0
56
354
1.68
2.99
2.6
2.6
36.17
32.42
u/l
0.44
47
297
199
1643
1.42
2.99
2.2
2.1
91.19
97.38
pmol/l
1.20
116
848
12
37
3.31
2.95
1.8
1.8
—
—
—
0
0
57
364
1.66
2.93
1.5
1.5
—
—
—
0
0
128
979
1.45
2.92
1.4
1.4
—
—
—
0
0
126
964
1.45
2.86
3.2
2.9
332.42
347.45
umol/l
0.84
117
856
13
47
2.82
2.84
1.9
1.6
36.33
32.52
g/l
0.63
13
41
11
33
3.40
2.83
2.1
1.9
1262.00
1051.57
e6/l
0.30
11
28
27
138
2.02
2.82
9.6
3.6
1.24
1.37
mmol/l
0.40
27
130
55
353
1.65
2.78
2.8
2.2
0.21
0.22
g/l
0.55
50
331
75
522
1.54
2.71
1.5
1.4
370.43
531.09
titre
0.88
23
119
17
73
2.39
2.69
8.5
6.7
105.88
104.87
mmol/l
0.46
17
67
17
73
2.39
2.69
8.5
6.7
10.41
10.93
mmol/l
0.32
17
67
23
113
2.10
2.67
1.5
1.4
232.94
300.32
ug/g
0.71
16
69
23
113
2.10
2.67
10.8
3.9
3.87
4.00
mmol/l
0.57
23
108
347
3204
1.58
2.67
5.6
5.3
1.88
1.93
mu/l
0.28
329
2934
59
392
1.59
2.60
1.5
1.6
—
—
—
0
0
13
50
2.65
2.55
1.2
1.3
—
—
—
0
0
183
1518
1.37
2.55
3.7
3.7
6.33
6.19
ph
0.79
82
866
12
45
2.72
2.47
2.8
3.0
—
—
—
0
0
72
507
1.51
2.46
1.3
1.2
—
—
—
0
0
11
38
2.95
2.43
1.9
1.4
0.49
0.32
g/l
—
6
29
11
38
2.95
2.43
1.9
1.4
7.44
6.78
g/l
—
6
30
226
1952
1.36
2.38
4.4
4.1
0.00
0.79
estimate
0.50
47
385
223
1927
1.35
2.32
4.4
4.1
0.00
3.95
estimate
0.50
51
411
112
868
1.40
2.32
3.8
3.9
—
0.38
—
0
8
29
164
1.83
2.30
2.0
2.0
—
—
—
0
0
15
66
2.32
2.27
2.0
1.9
0.65
0.88
g/l
—
10
55
76
551
1.47
2.25
2.2
1.9
—
—
—
0
0
84
622
1.44
2.23
1.2
1.3
10.46
12.19
u/ml
0.10
28
241
146
1189
1.36
2.22
2.9
2.5
56.05
64.74
u/l
0.88
132
1101
13
54
2.45
2.22
4.6
3.0
4.20
4.76
e9/l
0.41
13
54
17
80
2.17
2.22
3.9
2.7
60.21
57.59
%
0.34
17
80
91
688
1.42
2.16
1.3
1.3
104.50
37.26
iu/ml
0.80
23
218
220
1912
1.33
2.13
4.5
4.0
0.00
0.00
estimate
0.50
51
400
12
49
2.49
2.12
2.0
1.4
0.60
0.55
nmol/l
0.23
12
44
8
25
3.24
2.10
5.3
4.2
97.88
148.72
nmol/l
—
8
25
100
776
1.38
2.04
1.9
1.5
2.36
2.56
g/l
0.37
62
461
99
770
1.38
1.99
2.9
2.8
2.46
2.46
mmol/l
0.22
88
697
22
120
1.88
1.97
3.0
3.4
304.27
265.39
mg/l
0.08
11
51
38
244
1.62
1.95
1.5
1.2
138.80
260.98
u/ml
0.68
32
225
10
39
2.60
1.95
2.0
1.4
—
—
—
0
0
11
45
2.48
1.94
6.1
3.5
2.95
6.84
nmol/l
0.56
11
45
27
158
1.76
1.94
1.3
1.3
—
—
—
0
0
132
1079
1.33
1.92
1.8
1.7
18.99
20.70
nmol/l
0.87
118
902
16
79
2.07
1.88
1.6
1.9
—
—
—
0
0
9
34
2.68
1.87
1.1
1.3
—
—
—
0
0
107
851
1.35
1.86
3.2
2.6
3.73
5.21
e6/l
1.37
96
771
14
66
2.16
1.84
1.1
1.4
—
—
—
0
0
66
486
1.43
1.81
1.5
1.4
—
—
—
0
0
8
29
2.79
1.80
2.4
2.1
27.57
38.37
%
—
8
29
23
133
1.77
1.74
1.3
1.3
—
—
—
0
0
10
40
2.54
1.67
2.0
1.4
—
—
—
0
0
48
339
1.47
1.65
4.5
4.6
1.35
0.84
%
0.55
13
119
45
318
1.47
1.55
4.4
4.7
0.30
0.13
%
—
10
98
37
253
1.51
1.49
1.2
1.5
—
—
—
0
0
256
2335
1.26
1.46
4.5
3.4
50.46
49.58
u/l
0.04
248
2191
7
28
2.53
1.46
2.4
1.9
595.29
485.00
e6/l
—
7
21
28
181
1.59
1.44
4.4
3.7
—
—
—
0
0
9
39
2.34
1.44
3.1
1.4
118.72
31.76
ng/l
—
9
39
291
2700
1.28
1.41
4.2
4.2
14.88
14.92
pmol/l
0.10
267
2445
79
628
1.32
1.37
2.0
1.7
1132.83
1186.61
nmol/l
0.24
63
478
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
5
17
2.96
1.36
1.6
1.8
56.40
56.27
ug/l
—
5
17
5
17
2.96
1.36
4.4
2.9
1332.60
664.94
u/ml
—
5
17
14
75
1.90
1.36
3.8
3.1
29.00
32.58
umol/l
0.32
14
67
10
47
2.16
1.34
1.3
1.3
—
—
—
0
0
9
42
2.17
1.34
2.7
2.1
—
—
—
0
0
55
415
1.38
1.34
2.1
1.7
—
—
—
0
0
62
479
1.35
1.31
1.5
1.5
—
—
—
0
0
25
162
1.58
1.29
2.4
2.0
7.28
5.96
iu/ml
—
9
42
17
99
1.75
1.29
1.6
1.4
27707.36
16767.53
e6/l
0.29
11
70
5
18
2.80
1.29
1.2
2.1
—
—
—
0
0
5
18
2.80
1.29
13.6
16.8
1087.20
906.17
nmol/l
—
5
18
349
3333
1.34
1.24
5.5
5.3
5.95
5.98
mmol/l
0.19
324
3055
374
3612
1.46
1.23
16.5
12.6
24.83
26.15
u/l
1.09
368
3511
11
56
1.99
1.23
1.3
1.2
1.00
4.23
u/ml
—
5
26
8
38
2.13
1.19
1.1
1.2
—
—
—
0
0
8
39
2.07
1.16
1.1
1.1
—
—
—
0
0
5
20
2.52
1.15
1.2
2.0
—
—
—
0
0
44
329
1.38
1.15
4.8
5.1
0.11
0.18
%
—
9
91
34
243
1.44
1.14
1.1
1.3
—
—
—
0
0
344
3289
1.30
1.12
6.5
6.7
38.71
39.64
mmol/mol
1.50
323
3082
16
96
1.69
1.12
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.0
1.1
—
—
—
0
0
18
112
1.64
1.10
1.8
1.3
—
2.67
—
0
18
8
41
1.97
1.09
2.3
1.4
—
—
nmol/l
—
0
0
18
113
1.62
1.07
1.4
1.2
—
83.33
—
0
12
7
34
2.08
1.03
1.1
1.4
—
—
—
0
0
9
47
1.94
1.02
1.2
1.2
—
—
—
0
0
7
35
2.02
1.00
1.0
1.2
105.43
100.77
pmol/l
—
7
35
86
721
1.24
1.00
1.8
1.8
400.41
446.07
pmol/l
1.26
72
596
12
70
1.74
0.93
1.3
1.5
—
—
—
0
0
42
324
1.33
0.93
4.1
4.6
0.80
0.51
%
—
10
107
115
1306
0.83
0.90
3.3
3.3
—
—
—
0
0
15
96
1.58
0.85
1.1
1.4
—
—
—
0
0
6
31
1.95
0.84
1.8
1.9
—
—
—
0
0
361
3500
1.29
0.84
22.2
14.7
—
—
—
0
0
6
33
1.83
0.79
1.3
1.2
0.05
1.55
u/ml
—
6
18
37
289
1.31
0.77
5.2
3.7
—
—
—
0
0
98
857
1.19
0.76
1.4
1.3
4.16
1.40
u/ml
0.40
28
236
21
288
0.71
0.75
1.2
1.4
—
—
—
0
0
9
54
1.68
0.75
1.0
1.1
—
—
—
0
0
9
54
1.68
0.75
1.0
1.1
—
—
—
0
0
7
38
1.86
0.74
2.3
2.7
—
22.26
—
0
5
11
68
1.63
0.72
1.3
1.2
—
—
—
0
0
37
293
1.29
0.71
1.2
1.2
—
—
—
0
0
7
41
1.72
0.70
1.1
1.1
—
—
—
0
0
138
1250
1.16
0.69
3.5
3.5
30.91
52.98
mg/l
1.19
94
808
164
1505
1.15
0.69
1.9
2.0
1.32
1.34
mmol/l
0.13
141
1255
5
27
1.86
0.68
1.4
1.7
16.54
16.83
%
—
5
27
5
27
1.86
0.68
1.4
4.0
1180.40
1167.59
mg
—
5
27
20
145
1.40
0.67
2.1
2.8
—
—
—
0
0
21
154
1.38
0.66
2.0
1.5
0.23
0.35
mg/l
—
8
66
11
70
1.59
0.66
1.2
1.1
—
—
—
0
0
90
794
1.17
0.63
5.9
5.2
—
—
—
0
0
11
71
1.56
0.62
1.3
1.1
—
—
—
0
0
8
49
1.65
0.62
18.1
6.7
7.36
6.75
mmol/l
—
8
40
36
290
1.26
0.62
2.1
2.2
15.70
13.56
nmol/l
0.75
26
267
8
50
1.61
0.61
2.0
1.9
25.50
32.62
pg
—
8
50
10
64
1.58
0.59
1.3
1.5
—
—
—
0
0
10
64
1.58
0.59
1.3
1.5
—
—
—
0
0
10
64
1.58
0.59
1.3
1.5
—
—
—
0
0
10
64
1.58
0.59
1.3
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
0.49
—
0
13
142
1305
1.14
0.57
3.6
3.4
7.64
7.59
mmol/l
0.05
134
1099
25
317
0.77
0.56
1.4
1.6
—
—
—
0
0
9
62
1.46
0.53
1.3
1.0
—
—
—
0
0
6
39
1.55
0.53
1.2
3.4
—
—
—
0
0
6
40
1.51
0.52
3.7
1.8
89.88
89.54
%
—
6
40
11
75
1.48
0.51
4.3
2.5
9.39
8.92
pmol/l
0.06
11
75
10
67
1.51
0.50
1.2
1.3
—
—
—
0
0
10
68
1.48
0.47
2.3
2.0
5.26
4.56
mmol/24h
—
10
58
7
48
1.47
0.47
1.9
2.0
—
—
—
0
0
25
201
1.26
0.46
1.1
1.3
—
—
—
0
0
14
103
1.37
0.46
1.0
1.3
—
—
—
0
0
5
32
1.57
0.42
3.0
1.2
—
—
—
0
0
42
362
1.18
0.41
1.5
1.6
—
—
—
0
0
14
106
1.33
0.39
1.9
1.1
0.89
0.89
g/l
0.00
14
106
39
336
1.18
0.39
2.6
2.2
0.00
0.00
estimate
—
8
67
136
1277
1.10
0.37
4.2
4.1
8.34
9.24
mg/mmol
0.09
90
798
6
42
1.43
0.35
2.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
49
436
1.14
0.34
1.5
1.3
—
—
—
0
0
51
457
1.13
0.32
2.3
2.3
132.48
120.04
ug/g
0.16
46
378
115
1079
1.09
0.32
5.1
4.0
0.00
0.01
estimate
0.99
47
371
7
100
0.69
0.31
1.1
1.3
—
—
—
0
0
34
298
1.15
0.29
2.8
2.6
6.04
6.11
ph
0.14
24
204
8
110
0.72
0.29
15.8
11.2
—
—
—
0
0
19
226
0.83
0.28
1.8
1.8
—
—
—
0
0
38
338
1.14
0.27
4.1
4.2
7.38
7.35
ph
1.69
29
239
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
39
1.29
0.23
1.6
1.1
1.14
1.77
nmol/l
—
5
34
7
93
0.75
0.22
1.1
1.4
—
—
—
0
0
5
41
1.22
0.22
1.0
2.9
2.19
1.63
g/24h
—
5
29
21
241
0.86
0.22
1.2
1.9
3.43
3.42
mmol/l
0.00
15
182
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
8
101
0.79
0.21
1.1
1.3
—
—
—
0
0
8
101
0.79
0.21
1.1
1.3
—
—
—
0
0
8
101
0.79
0.21
1.1
1.3
—
—
—
0
0
15
126
1.20
0.21
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
124
1191
1.06
0.19
5.6
5.5
2.29
2.59
ug/l
0.26
113
1070
6
78
0.77
0.15
1.2
1.3
—
—
—
0
0
6
80
0.75
0.15
2.3
1.3
3.85
3.83
mmol/l
—
6
74
12
102
1.18
0.15
1.2
1.1
—
—
—
0
0
12
103
1.17
0.14
1.4
1.1
1.55
1.56
g/l
0.03
12
103
12
103
1.17
0.14
3.1
5.3
—
—
—
0
0
68
713
0.94
0.14
3.2
3.3
1.30
0.81
ug/l
0.91
48
462
110
1069
1.04
0.11
4.1
3.5
0.00
0.09
estimate
0.63
45
328
5
65
0.77
0.08
1.4
1.6
—
—
—
0
0
19
176
1.08
0.07
3.5
2.3
0.00
0.00
estimate
—
5
55
348
3460
1.04
0.07
6.4
6.1
2.58
2.67
mmol/l
1.16
326
3199
13
143
0.91
0.07
1.5
1.6
—
—
—
0
0
340
3390
1.02
0.02
5.3
5.2
1.42
1.47
mmol/l
1.29
319
3129
20
194
1.03
0.00
1.2
1.1
—
—
—
0
0
19
188
1.01
0.00
2.5
2.6
—
—
—
0
0
340
3402
1.00
0.00
5.5
5.4
4.46
4.59
mmol/l
1.49
319
3161
11
105
1.05
0.00
1.7
1.4
—
—
—
0
0
325
3253
1.00
0.00
4.5
4.4
1.23
1.28
mmol/l
0.86
305
2976
84
836
1.01
0.00
4.6
4.2
1.02
1.02
kg/l
0.73
59
572
18
184
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
60.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
57.60
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
6.54
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
6.56
—
0
7
0
5
0.00
0.00
0.0
1.6
—
38.20
—
0
5
7
69
1.01
-0.00
1.7
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
0.02
—
0
8
0
8
0.00
-0.00
0.0
2.4
—
2.75
—
0
8
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.87
—
0
6
32
320
1.00
-0.00
2.7
2.5
0.50
0.47
e6/l
0.02
32
305
0
6
0.00
-0.00
0.0
3.3
—
5.80
—
0
6
5
52
0.96
-0.00
1.0
1.1
—
25.00
—
0
11
146
1460
1.00
-0.00
4.8
4.0
0.00
0.04
estimate
1.81
43
335
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_INTRATHORACIC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.723 [1.35, 2.2] < 0.001
Birth year 0.99 [0.98, 1.0] 0.024

During the follow-up period (1.1.1998 — 31.12.2019), 170 out of 792 females with CD2_BENIGN_INTRATHORACIC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_INTRATHORACIC 1.914 [1.5, 2.44] < 0.001
Birth year 0.988 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 144 out of 631 males with CD2_BENIGN_INTRATHORACIC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_INTRATHORACIC.

N-year risk Females Males
1 0.14% 0.406%
5 0.988% 2.501%
10 2.339% 6.167%
15 4.24% 11.267%
20 7.286% 18.197%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_INTRATHORACIC – Benign neoplasm of other and unspecified intrathoracic organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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