thymus neoplasm: A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
93 |
4. Check minimum number of eventsNone |
93 |
5. Include endpointsNone |
93 |
6. Filter based on genotype QC (FinnGen only) |
82 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D15
- Name in latin
- Neoplasma benignum thymi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Thymus
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and unspecified intrathoracic organs
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 372 | 193 | 175 |
| Only index persons | 325 | 170 | 155 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.88 | 60.91 | 56.30 |
| Only index persons | 57.65 | 59.27 | 55.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 82 | 41 | 41 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 64.91 | 64.14 | 65.67 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 86
- Matched controls
- 860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
118.2
84
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
+∞
42.2
37
*
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
+∞
40.9
36
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
13.3
32.6
43
60
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
+∞
21.8
20
*
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
18.4
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.8
17.6
42
106
GEC23
NOMESCO Finland
Transsternal thymectomy
208.9
17.2
17
*
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
12.8
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.4
12.5
69
334
G70.0
ICD-10 Finland
Myasthenia gravis
124.6
10.7
11
*
N07AA02
ATC
pyridostigmine; systemic
124.6
10.7
11
*
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
10.6
10
*
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
10.6
10
*
GD1AD
NOMESCO Finland
Thorax CT examination
8.3
9.4
21
32
108
Kela drug reimbursment
Myasthenia gravis
99.4
8.6
9
*
ZXC96
NOMESCO Finland
Robot assisted procedure
19.6
8.3
12
7
WF003
NOMESCO Finland
Adjuvant radiotherapy
17.1
8.0
12
8
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.9
7.6
17
26
WX402
NOMESCO Finland
General anaesthesia
3.6
7.1
33
128
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.0
6.0
20
61
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
362
5.58
10.56
3.0
2.8
—
—
estimate
—
0
0
45
188
3.92
9.03
2.5
2.6
—
—
—
0
0
22
58
4.75
8.13
14.9
10.4
0.57
0.65
%
0.46
22
58
21
59
4.39
7.12
15.5
10.3
1.17
1.47
%
0.71
21
59
71
461
4.10
6.35
14.8
9.5
3.95
4.11
e9/l
0.30
62
397
28
117
3.07
5.16
13.7
7.7
103.93
103.70
mmol/l
0.08
28
117
28
119
3.01
4.99
3.8
3.3
5.59
2.53
e6/l
0.37
14
57
50
291
2.72
4.88
4.5
3.6
—
—
—
0
0
17
56
3.54
4.54
7.6
8.8
25.79
25.41
mmol/l
0.23
17
56
9
12
8.22
4.48
1.2
1.3
—
—
—
0
0
41
227
2.54
4.29
3.9
3.3
0.26
0.52
e6/l
0.72
30
160
20
76
3.13
4.26
1.5
1.4
—
—
—
0
0
29
137
2.68
4.17
3.8
3.1
0.59
0.81
e6/l
0.30
15
75
44
265
2.35
3.69
3.0
3.2
24.07
28.87
u/l
2.00
44
253
7
11
6.81
3.25
1.1
1.4
—
—
—
0
0
13
41
3.55
3.23
1.5
1.4
—
—
—
0
0
22
104
2.50
3.08
2.0
1.6
—
—
—
0
0
17
71
2.74
3.03
2.1
3.1
64.81
67.21
g/l
0.77
17
65
6
9
7.06
2.91
1.0
1.3
—
—
—
0
0
40
251
2.11
2.86
2.5
2.2
159.00
172.28
u/l
0.12
40
239
12
41
3.23
2.75
3.2
2.5
—
—
—
0
0
8
19
4.53
2.75
1.0
1.4
—
—
—
0
0
27
148
2.20
2.69
2.5
3.1
0.79
0.81
mmol/l
0.35
27
142
59
435
2.13
2.68
4.3
3.9
0.00
0.00
estimate
-0.00
12
80
8
21
4.09
2.53
1.0
1.1
—
—
—
0
0
58
430
2.07
2.53
4.2
3.9
0.00
0.00
estimate
-0.00
13
88
57
426
2.00
2.36
4.4
3.8
0.00
0.00
estimate
-0.00
13
87
8
23
3.72
2.33
2.3
1.6
—
—
—
0
0
48
340
1.93
2.31
1.9
2.0
92.12
100.17
pmol/l
0.86
35
168
28
166
2.02
2.24
3.4
3.3
43.10
129.70
ng/l
1.08
21
135
19
99
2.18
2.11
2.2
1.7
—
—
—
0
0
23
131
2.03
2.04
2.5
1.7
—
—
—
0
0
11
46
2.60
1.94
4.6
3.9
1.90
1.26
mmol/l
0.22
11
40
8
30
2.83
1.77
1.6
1.3
—
—
—
0
0
8
31
2.74
1.71
3.3
1.1
0.00
0.00
g/l
—
8
26
13
66
2.14
1.53
1.6
1.6
—
—
—
0
0
43
322
1.67
1.52
4.8
4.0
24.02
43.35
ng/l
1.00
34
237
23
145
1.80
1.49
1.2
1.3
29.12
32.09
iu/ml
—
5
46
10
47
2.28
1.40
1.5
1.1
—
—
—
0
0
6
23
2.73
1.39
23.3
4.0
3.62
4.08
mmol/l
—
6
23
60
497
1.69
1.38
4.2
3.4
74.55
56.46
u/l
0.29
60
463
36
267
1.60
1.27
3.0
2.7
61.58
72.27
u/l
0.28
36
249
6
25
2.50
1.26
1.5
1.2
—
—
—
0
0
20
127
1.75
1.26
2.5
2.6
21.39
23.07
%
0.21
20
119
35
259
1.59
1.24
4.1
4.0
12.41
10.68
mg/mmol
0.08
21
156
11
57
2.07
1.23
4.8
3.7
5.20
5.13
kpa
0.12
11
57
8
38
2.22
1.22
1.1
1.3
—
145.08
—
0
15
6
26
2.40
1.21
3.8
2.8
26.80
25.21
mmol/l
—
6
26
21
137
1.70
1.20
2.6
2.5
2.37
2.32
g/l
0.16
21
126
25
174
1.62
1.12
3.0
3.1
2.44
2.46
mmol/l
0.49
20
150
5
21
2.46
1.10
2.0
1.1
—
—
—
0
0
79
729
2.03
1.10
25.4
16.4
79.78
79.44
ml/min/173m2
0.05
74
679
21
142
1.63
1.05
2.6
2.6
12.75
13.18
umol/l
0.09
21
133
5
22
2.35
1.05
1.2
1.4
—
—
—
0
0
20
134
1.64
1.04
1.2
1.3
1.06
9.48
u/ml
—
7
61
17
109
1.70
1.03
1.4
1.4
—
—
—
0
0
16
101
1.72
1.02
5.9
4.5
292.88
252.03
u/l
0.52
16
93
0
29
0.00
1.00
0.0
1.7
—
—
—
0
0
6
28
2.23
0.93
1.5
1.4
—
—
—
0
0
8
42
2.00
0.91
6.9
2.6
1.13
1.40
%
—
8
42
6
30
2.07
0.89
1.8
1.4
—
—
—
0
0
6
32
1.94
0.83
6.2
4.2
24.23
25.09
mmol/l
—
6
32
5
25
2.06
0.74
3.2
1.9
—
—
—
0
0
5
26
1.98
0.72
1.0
1.6
—
—
—
0
0
6
105
0.54
0.67
10.7
8.5
—
—
—
0
0
49
426
1.35
0.64
3.4
2.9
—
—
—
0
0
63
570
1.39
0.63
4.1
4.3
14.80
15.02
pmol/l
0.22
54
508
9
59
1.59
0.57
2.9
1.7
—
—
—
0
0
10
67
1.56
0.52
8.7
3.6
69.30
81.87
ng/l
—
10
56
11
78
1.47
0.46
1.3
2.7
24.56
8.81
ug/l
0.33
11
68
8
57
1.44
0.43
2.6
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
4.09
—
0
12
6
42
1.46
0.36
3.0
3.3
4.73
4.51
pmol/l
—
6
36
27
231
1.25
0.36
3.4
3.2
0.00
0.00
estimate
—
10
69
20
237
0.80
0.33
3.6
4.6
16.36
22.77
%
1.63
11
128
29
254
1.21
0.31
5.1
3.9
0.00
0.00
estimate
-0.00
12
80
5
70
0.70
0.27
1.4
2.7
345.00
381.29
nmol/l
—
5
65
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
21
188
1.15
0.17
4.7
4.5
1.02
1.02
kg/l
0.48
16
128
77
755
1.19
0.14
5.8
6.1
2.45
2.65
mmol/l
1.17
72
695
10
87
1.17
0.10
2.8
3.8
—
—
—
0
0
19
180
1.07
0.04
1.1
1.3
0.77
1.72
u/ml
—
6
50
10
108
0.92
0.03
1.5
1.5
—
—
—
0
0
75
743
1.07
0.02
4.9
5.2
1.43
1.47
mmol/l
0.46
70
678
30
293
1.04
0.01
7.2
5.2
3.29
1.99
ug/l
0.66
30
256
33
327
1.01
0.00
4.6
3.9
0.00
0.00
estimate
—
9
70
75
746
1.04
0.00
5.1
5.3
4.34
4.59
mmol/l
1.33
70
686
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
19.22
—
0
6
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
681.80
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
89.33
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
102.92
—
0
6
7
77
0.90
-0.00
3.1
2.7
0.14
0.21
e6/l
—
7
72
0
5
0.00
-0.00
0.0
1.8
—
9.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_THYMUS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_THYMUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_THYMUS – Benign neoplasm: Thymus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data