No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
648 |
4. Check minimum number of eventsNone |
648 |
5. Include endpointsNone |
648 |
6. Filter based on genotype QC (FinnGen only) |
580 |
Control definitions (FinnGen only)
- Control exclude
- K11_LIVER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K70-K77
- Name in latin
- Morbus hepatis toxicus
Similar endpoints
↥List of similar endpoints to
Toxic liver disease
based on the number of shared cases.
Similar with more cases:
- Diseases of liver
- Gastrointestinal diseases
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3897 | 2092 | 1772 |
| Only index persons | 3296 | 1812 | 1484 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.05 |
| Only index persons | 0.06 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 56.47 | 57.86 | 54.71 |
| Only index persons | 55.21 | 56.21 | 53.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 580 | 344 | 236 |
| Unadjusted period prevalence (%) | 0.12 | 0.12 | 0.11 |
| Median age at first event (years) | 55.33 | 54.57 | 56.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 599
- Matched controls
- 5990
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
305.1
266
*
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
+∞
175.9
160
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
49.8
169.6
100
24
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
34.9
110.3
71
23
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
19.4
99.7
81
48
A05AA02
ATC
ursodeoxycholic acid; oral
34.5
96.2
62
20
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.3
92.5
162
288
K71.0
ICD-10 Finland
Toxic liver disease with cholestasis
+∞
87.7
82
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
87.7
82
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.5
73.9
179
428
K76.9
ICD-10 Finland
Liver disease, unspecified
158.2
67.5
70
5
K71.1
ICD-10 Finland
Toxic liver disease with hepatic necrosis
+∞
45.4
43
*
L04AX01
ATC
azathioprine; systemic
7.4
44.2
68
102
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
10.3
40.9
47
49
K71.6
ICD-10 Finland
Toxic liver disease with hepatitis, not elsewhere classified
+∞
40.0
38
*
L04AA06
ATC
mycophenolic acid; systemic
12.7
37.1
37
31
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
35.8
34
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.9
34.7
120
363
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
9.7
33.4
40
44
K70.1
ICD-10 Finland
Alcoholic hepatitis
+∞
32.6
31
*
R94.5
ICD-10 Finland
Abnormal results of liver function studies
12.5
31.0
31
26
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
12.1
30.3
31
27
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.5
28.5
32
32
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
27.5
226
1116
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
25.2
24
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
24.1
23
*
K72.9
ICD-10 Finland
Hepatic failure, unspecified
+∞
24.1
23
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
23.7
340
2127
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.9
22.9
53
117
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
24.1
22.8
32
14
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
22.3
175
832
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
+∞
21.0
20
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.4
20.1
41
81
C10AC01
ATC
colestyramine; oral
6.0
20.0
36
63
ZX120
NOMESCO Finland
Intravenous
3.2
19.5
85
294
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.0
19.5
43
91
A06AD11
ATC
lactulose; oral
2.8
19.2
113
462
H02AB06
ATC
prednisolone; systemic
2.2
19.0
326
2126
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.7
18.9
64
188
L04AD01
ATC
ciclosporin; systemic
7.6
18.8
27
37
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
195.9
18.6
19
*
N05CF01
ATC
zopiclone; oral
2.2
18.3
237
1381
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
17.8
128
577
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
98.0
17.7
19
*
WX892
NOMESCO Finland
Monitored bed care
3.4
17.6
69
223
N02AX02
ATC
tramadol; systemic, rectal
2.1
17.5
297
1911
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
17.2
234
1381
K71.3
ICD-10 Finland
Toxic liver disease with chronic persistent hepatitis
+∞
16.7
16
*
Z94.4
ICD-10 Finland
Liver transplant status
174.7
16.6
17
*
R50.9
ICD-10 Finland
Fever, unspecified
2.5
16.5
121
550
N07BB01
ATC
disulfiram; oral
4.0
16.4
49
132
A07EA06
ATC
budesonide; oral, local oral
4.2
16.2
44
110
UJK02
NOMESCO Finland
ERCP
5.8
15.2
28
50
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
15.2
87
349
N05AH04
ATC
quetiapine; oral
2.3
15.2
139
695
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.1
15.2
32
65
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
15.1
99
425
A02BC02
ATC
pantoprazole; systemic
2.1
14.8
435
3332
TK800
NOMESCO Finland
Hemodialysis
6.3
14.8
25
41
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
14.6
14
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
14.6
14
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
14.6
14
*
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
+∞
14.6
14
*
UJF32
NOMESCO Finland
Coloscopy
2.1
14.6
178
998
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.5
14.4
52
159
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.8
13.9
32
70
K83.0
ICD-10 Finland
Cholangitis
11.8
13.9
25
22
127
Kela drug reimbursment
Transplant complication
11.3
13.6
25
23
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
10.4
13.6
26
26
P15
ICPC
Chronic alcohol abuse
4.8
13.4
31
68
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
13.3
123
615
P01BA02
ATC
hydroxychloroquine; oral
2.8
13.2
69
263
K92.0
ICD-10 Finland
Haematemesis
6.3
13.0
22
36
J01MA12
ATC
levofloxacin; systemic
2.2
13.0
126
642
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
12.5
12
*
C03DA01
ATC
spironolactone; oral
2.5
12.5
85
370
C03CA01
ATC
furosemide; systemic
2.0
12.5
186
1111
H02AB04
ATC
methylprednisolone; systemic
2.3
12.5
107
517
L04AX03
ATC
methotrexate; systemic
2.6
12.4
79
333
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
12.4
101
478
L04AA13
ATC
[U] leflunomide
4.8
12.2
28
61
N05BA04
ATC
oxazepam; oral
2.0
12.1
183
1097
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
12.0
170
996
N03AX16
ATC
[U] pregabalin
2.0
12.0
158
903
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
11.9
107
527
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
11.7
109
544
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
11.7
238
1568
K70.0
ICD-10 Finland
Alcoholic fatty liver
66.3
11.6
13
*
N05BA01
ATC
diazepam; systemic, rectal
2.3
11.5
98
471
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
11.5
72
301
K76.89
ICD-10 Finland
Other specified diseases of liver
+∞
11.5
11
*
N06AX11
ATC
mirtazapine; oral
1.9
11.4
224
1457
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
11.4
92
432
N05CD07
ATC
temazepam; oral
2.4
11.3
84
381
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
61.1
10.7
12
*
Z3231
NOMESCO Finland
Registered nurse
1.9
10.6
177
1089
ZXD05
NOMESCO Finland
Urgent procedure
1.8
10.4
192
1219
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.3
10.4
21
41
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.8
10.3
55
212
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
10.3
57
224
D97
ICPC
Liver disease NOS
23.8
10.3
14
6
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.0
10.2
29
75
R4110
NOMESCO Finland
Physiotherapy
1.8
10.1
182
1144
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
10.1
95
475
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.4
9.9
25
59
L04AB04
ATC
adalimumab; parenteral
4.5
9.9
24
55
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.3
9.7
74
339
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.0
9.5
43
151
H02AB07
ATC
prednisone; oral
2.1
9.5
95
486
J01FF01
ATC
clindamycin; systemic
1.8
9.5
171
1072
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
12.6
9.4
16
13
K71.8
ICD-10 Finland
Toxic liver disease with other disorders of liver
+∞
9.4
9
*
R53
ICD-10 Finland
Malaise and fatigue
1.8
9.4
167
1044
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.4
9.3
34
105
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.4
9.3
33
100
M05BA04
ATC
alendronic acid; oral
2.5
9.1
59
250
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.7
9.1
16
14
L04AD02
ATC
tacrolimus; systemic
11.7
9.1
16
14
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
9.1
53
214
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.8
9.0
27
73
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
8.9
123
707
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.9
8.9
26
69
ZXE00
NOMESCO Finland
One hour or less
1.7
8.8
234
1637
N05AH03
ATC
olanzapine; systemic
2.6
8.7
51
206
L04AA01
ATC
[U] ciclosporin
7.8
8.7
19
25
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
8.7
35
115
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.5
8.7
54
225
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.0
8.7
39
137
J01MA02
ATC
ciprofloxacin; systemic
1.7
8.6
227
1581
K85
ICD-10 Finland
Acute pancreatitis
6.6
8.5
21
33
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.8
8.5
26
71
JN4AD
NOMESCO Finland
Body CT examination
2.2
8.4
77
380
N06AB04
ATC
citalopram; systemic
1.8
8.4
135
815
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
8.3
8
*
JJ5AT, ,
NOMESCO Finland
+∞
8.3
8
*
WX882
NOMESCO Finland
High dependency care
4.2
8.3
22
54
ZY010
NOMESCO Finland
Hospital outpatient
2.7
8.2
45
176
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
8.2
86
448
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.2
72
350
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
8.1
123
728
TKC20
NOMESCO Finland
Catheterisation of bladder
2.6
8.0
47
190
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
7.9
36
127
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.9
248
1799
B01AB05
ATC
enoxaparin; parenteral
1.7
7.9
190
1286
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
7.9
87
462
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.8
118
697
A02BC05
ATC
esomeprazole; systemic
1.6
7.8
246
1785
N06AX16
ATC
venlafaxine; oral
2.0
7.8
95
523
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
7.6
7.7
17
23
F10.24
ICD-10 Finland
Alcohol depence active use
4.6
7.7
18
40
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
7.6
42
165
A07EC02
ATC
mesalazine; oral, rectal
2.7
7.6
42
165
A07EC01
ATC
sulfasalazine; oral, rectal
2.3
7.6
57
259
L40.5
ICD-10 Finland
Arthropathic psoriasis
4.5
7.5
18
41
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
81.1
7.4
8
*
N05CF02
ATC
zolpidem; oral
1.8
7.4
113
669
N05AX12
ATC
aripiprazole; systemic
3.0
7.4
32
110
A10AB05
ATC
insulin aspart; parenteral
2.4
7.4
52
230
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
7.4
28
89
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
7.3
66
324
K71.4
ICD-10 Finland
Toxic liver disease with chronic lobular hepatitis
+∞
7.3
7
*
K71.7
ICD-10 Finland
Toxic liver disease with fibrosis and cirrhosis of liver
+∞
7.3
7
*
K71.5
ICD-10 Finland
Toxic liver disease with chronic active hepatitis
+∞
7.3
7
*
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
6.4
7.3
18
29
N06AA09
ATC
amitriptyline; systemic
2.2
7.3
63
304
C07AA05
ATC
propranolol; systemic
1.8
7.2
128
793
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.6
7.2
41
164
JJA20
NOMESCO Finland
Open biopsy of liver
30.4
7.2
9
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.1
7.1
19
47
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
7.1
57
267
N17.8
ICD-10 Finland
Other acute renal failure
8.9
7.1
14
16
A03
ICPC
Fever
1.8
7.1
107
631
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
7.1
46
196
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.1
7.0
16
23
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
7.1
7.0
16
23
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
6.9
66
331
L01BA01
ATC
methotrexate; systemic
3.1
6.9
29
98
SPAT1262
SPAT
Handing over of treatment supplies
1.9
6.9
100
582
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.8
6.9
35
132
N06AX12
ATC
bupropion; oral
2.4
6.8
48
212
N06AB05
ATC
paroxetine; oral
2.5
6.8
42
175
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
16.9
6.8
10
6
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
6.7
60
293
N02AA05
ATC
oxycodone; systemic
1.8
6.7
108
648
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
6.7
57
274
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.6
6.7
38
152
K83.1
ICD-10 Finland
Obstruction of bile duct
5.6
6.7
18
33
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
6.6
24
74
N05AA02
ATC
levomepromazine; systemic
2.9
6.6
31
112
U02
ICPC
Urinary frequency/urgency
1.9
6.6
94
544
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
6.6
66
338
AA1AD
NOMESCO Finland
CT of head and brain
1.6
6.5
166
1132
M01CB01
ATC
sodium aurothiomalate; parenteral
6.3
6.5
16
26
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
5.8
6.5
17
30
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.3
6.5
24
75
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.7
6.4
33
125
WW200
NOMESCO Finland
Immunization
3.5
6.3
21
61
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.8
6.3
30
109
ZXE90
NOMESCO Finland
More than 22 hours
18.2
6.3
9
5
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
6.3
6
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
+∞
6.3
6
*
K01
ICPC
Heart pain
7.1
6.2
14
20
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
6.2
62
316
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
27.0
6.2
8
*
N06AB10
ATC
escitalopram; oral
1.7
6.2
126
809
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
5.8
6.2
16
28
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
6.2
32
122
A11CC03
ATC
alfacalcidol; systemic
3.8
6.1
18
48
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.2
6.1
24
78
P19
ICPC
Drug abuse
12.7
6.1
10
8
ZXA10
NOMESCO Finland
Bilateral
1.8
6.1
109
675
C07AB07
ATC
bisoprolol; oral
1.5
6.1
276
2145
E0000UV, ,
ATC
1.5
6.1
244
1847
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
125
21
74.96
229.30
1.2
1.0
—
—
—
0
0
217
300
10.77
159.97
1.6
1.8
1.23
1.55
g/l
0.68
209
279
238
379
9.76
156.15
2.7
3.0
10.41
10.19
g/l
0.34
233
352
245
438
8.77
144.31
3.7
2.1
0.20
0.22
g/l
3.94
228
420
109
75
17.54
125.20
4.6
2.2
36.76
30.04
umol/l
0.92
103
65
110
82
16.21
120.89
2.0
3.3
1030.83
3187.44
u/ml
—
6
9
115
99
14.14
116.10
3.5
6.0
983.36
195.60
iu/ml
—
11
10
77
34
25.84
107.63
1.3
1.1
—
—
titre
—
0
0
233
596
5.76
90.93
7.0
2.4
26.07
6.98
umol/l
5.96
220
529
94
94
11.68
85.39
1.3
1.3
234.89
224.33
u/ml
0.10
64
53
82
84
11.15
72.97
1.5
1.4
158.08
147.50
au/ml
0.23
26
27
393
1775
4.53
70.32
9.6
3.1
111.90
30.33
u/l
5.85
383
1686
81
90
10.25
67.90
1.6
1.4
—
—
—
0
0
439
2224
4.65
65.21
10.4
4.6
34.51
36.14
g/l
7.81
428
2089
54
41
14.38
57.79
1.2
1.0
—
—
—
0
0
481
2753
4.79
56.80
16.8
6.1
21.84
11.05
umol/l
7.64
473
2625
272
1109
3.66
52.56
1.7
1.4
2.44
2.26
g/l
0.80
219
671
92
171
6.17
48.81
1.3
1.2
—
—
—
0
0
203
719
3.76
47.94
3.2
2.4
25.59
22.99
%
1.34
198
675
288
1296
3.35
46.23
11.4
3.6
86.55
91.85
%
2.57
283
1273
335
1656
3.32
45.82
5.1
2.4
57.06
62.59
u/l
0.72
320
1548
100
213
5.44
45.74
2.0
1.6
0.32
0.34
mg/l
0.11
49
92
410
2326
3.42
43.69
16.2
12.5
1.19
1.22
inr
0.53
345
1922
203
783
3.41
41.15
3.4
2.4
2.35
2.34
g/l
0.06
192
732
206
847
3.18
37.00
3.5
2.4
14.47
13.42
umol/l
0.93
200
792
147
497
3.59
36.19
5.0
2.3
592.57
33.90
u/l
0.51
133
415
33
24
14.49
35.90
2.0
2.3
211.40
65.73
umol/l
0.95
15
15
164
633
3.19
32.27
3.0
1.8
1.69
1.47
%
3.33
145
564
129
435
3.50
31.56
12.7
6.3
8.99
9.33
mmol/l
0.24
121
415
31
26
12.52
30.98
6.2
1.3
100.84
103.96
%
0.12
31
26
451
3005
3.03
30.88
18.0
9.8
4.22
4.02
e9/l
1.00
402
2624
145
546
3.18
29.50
5.7
4.9
266.95
250.68
u/l
0.54
137
520
377
2323
2.68
29.47
11.3
6.3
1.20
1.21
mmol/l
1.97
359
2146
532
3973
4.03
28.58
22.7
7.8
116.91
77.31
u/l
11.71
520
3766
397
2589
2.58
26.30
13.0
6.9
1.21
1.21
mmol/l
0.47
340
2244
30
34
9.24
24.37
1.7
1.7
—
—
—
0
0
262
1455
2.42
24.11
4.4
3.1
0.55
0.35
e6/l
0.53
200
1044
481
3552
2.80
22.88
9.4
3.1
134.85
43.56
u/l
10.46
465
3367
180
859
2.57
22.82
6.2
3.3
0.81
0.83
mmol/l
1.45
172
825
39
69
5.98
21.44
1.4
1.3
—
—
—
0
0
149
670
2.63
21.17
10.4
5.5
1.04
1.04
mmol/l
0.03
142
627
177
866
2.48
21.05
2.3
1.9
—
—
—
0
0
144
649
2.60
20.28
2.1
1.9
—
—
—
0
0
351
2336
2.21
19.70
19.3
11.0
0.02
0.00
e9/l
0.50
287
1932
232
1317
2.24
19.30
3.5
2.2
2.57
2.95
mg/l
2.09
203
1135
278
1702
2.18
19.10
4.8
3.2
39.40
101.58
e6/l
0.86
218
1292
307
1958
2.17
18.95
5.5
3.8
86.51
102.02
e6/l
0.12
222
1365
135
613
2.55
18.58
2.2
1.9
—
—
—
0
0
363
2492
2.16
18.27
4.9
3.0
287.50
117.66
ug/l
2.21
343
2337
421
3068
2.25
18.14
10.4
4.9
6.70
6.59
mmol/l
0.52
401
2897
208
1170
2.19
17.34
3.7
2.6
5.90
6.03
e6/l
0.05
194
1067
221
1279
2.15
17.09
1.4
1.3
0.92
2.08
u/ml
1.16
41
359
114
498
2.59
16.88
8.0
3.8
1.70
1.91
mmol/l
0.23
102
430
70
237
3.21
16.56
2.8
2.0
4.06
7.67
iu/ml
0.92
14
59
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
46
118
4.14
16.40
3.4
2.5
0.28
0.38
iu/ml
1.03
25
63
93
372
2.78
16.37
1.7
1.7
—
—
—
0
0
257
1612
2.04
15.73
2.9
2.1
134.47
221.88
u/l
1.34
244
1527
279
1810
2.01
15.47
5.0
3.4
2.34
2.36
mmol/l
1.43
253
1651
336
2343
1.99
14.98
3.7
2.4
77.79
76.69
nmol/l
0.30
316
2125
166
902
2.16
14.75
3.8
2.8
1.34
0.98
e6/l
0.53
88
460
155
825
2.19
14.48
3.9
3.0
2.51
2.20
e6/l
0.16
77
381
381
2823
1.96
13.70
5.1
3.9
59.33
6.04
estimate
1.13
86
580
479
3868
2.19
13.31
7.9
4.4
16.14
11.29
mm/h
7.84
454
3615
56
196
3.05
12.48
3.7
3.2
22.45
1348.80
u/ml
1.16
48
172
377
2857
1.86
11.82
5.1
3.9
0.00
0.01
estimate
0.80
78
537
58
215
2.88
11.68
2.1
1.9
1.30
1.49
g/l
0.72
49
196
370
2797
1.84
11.59
5.1
3.8
0.00
0.00
estimate
0.50
79
568
53
189
2.98
11.43
1.7
1.6
0.01
0.03
iu/ml
—
8
29
169
1004
1.95
11.38
5.7
3.9
258.75
445.17
ng/l
0.59
133
752
100
497
2.21
10.84
4.1
4.4
24.28
16.49
ug/l
0.13
83
404
57
223
2.72
10.37
1.4
1.2
3.78
1.98
u/ml
—
5
15
109
571
2.11
10.31
10.8
8.1
0.47
0.87
mmol/l
0.48
81
485
139
796
1.97
10.30
2.0
1.7
1224.89
1208.42
nmol/l
0.06
111
604
17
13
13.42
10.21
3.7
2.3
0.58
0.60
mmol/l
0.40
17
13
50
187
2.83
9.90
8.0
3.3
1.59
1.44
mg/l
0.73
50
167
222
1497
1.77
9.71
1.9
1.7
19.45
20.74
nmol/l
0.59
201
1269
57
239
2.53
9.03
1.8
2.4
46.23
39.48
u/l
0.69
51
222
322
2445
1.69
8.90
4.3
2.7
—
—
estimate
—
0
0
303
2274
1.67
8.68
2.5
2.1
97.47
97.06
pmol/l
0.05
168
1174
95
514
2.01
8.15
4.5
3.1
—
—
—
0
0
47
191
2.59
7.95
1.6
1.8
1.31
3.28
ug/l
0.65
42
174
247
1788
1.65
7.93
5.5
3.3
7.41
7.79
mmol/l
0.58
209
1513
38
140
2.83
7.76
1.6
1.7
—
—
—
0
0
188
1276
1.69
7.69
4.4
2.2
—
—
—
0
0
35
124
2.94
7.66
1.3
1.8
—
—
—
0
0
18
41
4.50
7.47
1.2
1.2
—
—
—
0
0
18
41
4.50
7.47
1.2
1.2
—
—
—
0
0
14
15
9.53
7.31
1.0
1.0
—
—
—
0
0
21
55
3.92
7.31
1.2
1.2
—
—
—
0
0
38
145
2.73
7.28
1.7
1.7
—
—
—
0
0
28
90
3.21
7.22
1.6
1.9
—
—
—
0
0
63
306
2.18
7.17
2.0
1.7
—
—
—
0
0
19
47
4.14
7.13
1.2
1.1
—
—
—
0
0
18
43
4.28
7.05
1.2
1.2
—
—
—
0
0
18
43
4.28
7.05
1.2
1.2
—
—
—
0
0
158
1047
1.69
6.97
4.0
2.8
2.46
2.45
mmol/l
0.48
136
941
60
289
2.20
6.97
6.7
3.1
0.66
0.63
%
0.30
60
289
33
124
2.76
6.52
1.3
1.6
—
—
—
0
0
180
1269
1.60
6.11
6.7
4.0
1.02
1.02
kg/l
0.81
140
853
24
78
3.16
6.10
1.3
1.7
—
—
—
0
0
28
101
2.86
5.97
1.2
1.6
—
—
—
0
0
58
294
2.08
5.93
6.9
3.2
1.26
1.21
%
0.15
58
294
32
128
2.58
5.63
5.3
2.8
2.50
2.08
index
0.20
18
76
63
339
1.96
5.47
3.8
3.8
4.27
4.54
pmol/l
1.29
55
304
38
168
2.35
5.42
4.1
2.0
86.37
93.88
%
0.80
38
162
32
131
2.52
5.38
1.7
1.5
—
—
—
0
0
9
8
11.40
5.30
2.7
1.0
5.00
5.25
ug/l
—
9
8
169
1213
1.55
5.19
2.3
1.7
1.54
1.16
mg/l
0.54
132
940
549
5076
1.98
5.17
34.2
14.9
19.60
23.05
mg/l
2.82
502
4143
54
281
2.01
5.16
1.6
1.4
—
—
—
0
0
15
40
3.82
5.12
2.1
2.0
—
—
—
0
0
69
392
1.86
5.10
5.2
3.6
1.21
1.23
mmol/l
0.83
61
337
185
1361
1.52
5.06
3.3
2.7
329.60
340.22
umol/l
0.70
169
1205
37
167
2.30
5.05
3.8
3.5
1.61
1.28
mmol/l
1.30
37
162
20
67
3.05
4.87
1.5
1.7
—
—
—
0
0
253
1996
1.46
4.85
5.0
3.8
85.99
67.68
ng/l
0.14
181
1393
36
164
2.27
4.82
1.7
1.5
327.63
311.51
ug/g
0.17
25
101
15
43
3.55
4.64
5.3
2.5
13.30
12.70
index
—
10
30
25
98
2.62
4.61
1.6
1.2
—
—
—
0
0
25
98
2.62
4.61
1.6
1.2
—
—
—
0
0
26
104
2.57
4.60
1.8
1.4
—
—
—
0
0
70
414
1.78
4.55
2.9
2.5
6.93
7.31
ug/l
0.07
61
371
18
59
3.11
4.55
3.6
4.1
—
—
—
0
0
554
5176
1.94
4.47
36.6
17.4
139.17
139.70
mmol/l
4.79
545
5080
51
275
1.93
4.43
7.0
3.5
49.41
50.45
%
0.11
51
269
25
101
2.54
4.35
1.3
1.6
—
—
—
0
0
554
5183
1.92
4.35
37.1
17.6
3.96
3.97
mmol/l
0.47
545
5076
18
61
3.01
4.31
2.0
1.7
33.06
32.79
pg
0.08
18
61
104
697
1.60
4.24
3.6
2.5
195.28
127.88
ug/g
0.73
83
560
217
1699
1.43
4.19
5.1
4.1
6.74
6.85
mg/mmol
0.02
138
1044
33
155
2.19
4.14
2.5
2.2
3.56
4.61
iu/l
0.30
12
67
35
169
2.14
4.10
3.6
2.6
—
—
—
0
0
17
59
2.94
3.93
1.4
1.2
—
—
—
0
0
34
166
2.11
3.89
1.3
1.3
381.67
233.16
miu/ml
—
9
86
262
2147
1.39
3.81
5.2
3.7
0.00
0.03
estimate
1.71
69
475
19
72
2.69
3.76
1.5
1.7
—
—
—
0
0
33
162
2.10
3.73
1.2
1.1
—
—
—
0
0
33
162
2.10
3.73
1.2
1.1
—
—
—
0
0
372
3256
1.38
3.48
3.3
3.1
—
—
—
0
0
32
160
2.06
3.46
1.4
1.3
—
—
—
0
0
199
1579
1.39
3.43
5.9
3.9
0.00
0.01
estimate
0.69
80
540
139
1037
1.44
3.39
1.9
1.7
135000532.51
23958764.66
pmol/l
0.38
120
864
35
185
1.95
3.27
3.4
2.0
1328.74
3929.44
u/l
0.60
11
76
16
60
2.71
3.25
2.2
1.7
—
—
—
0
0
193
1538
1.38
3.21
2.9
3.3
2653.76
1087.38
ng/l
0.85
170
1302
10
25
4.05
3.09
1.3
1.1
—
—
—
0
0
25
120
2.13
3.02
3.0
2.2
132.85
127.99
g/l
0.41
20
96
32
170
1.93
2.96
1.7
3.4
36.46
75.53
mg/l
0.57
26
145
32
170
1.93
2.96
1.7
3.4
26.75
42.26
mg/l
0.64
26
145
13
46
2.87
2.93
1.4
1.6
—
—
—
0
0
66
434
1.59
2.93
6.7
2.7
59.14
68.26
ml/min/173m2
0.96
28
191
15
59
2.58
2.80
1.1
1.3
—
—
—
0
0
29
154
1.93
2.70
1.7
3.4
1.53
2.35
ratio
0.78
16
88
13
49
2.69
2.64
1.6
1.6
—
—
—
0
0
13
49
2.69
2.64
1.6
1.6
—
—
—
0
0
13
49
2.69
2.64
1.6
1.6
—
—
—
0
0
14
55
2.58
2.63
2.2
1.8
—
—
—
0
0
10
30
3.37
2.61
6.1
2.4
1.10
0.80
index
—
10
30
9
25
3.64
2.58
2.3
2.1
103.47
121.42
ng/l
—
9
25
507
4755
1.43
2.58
7.2
5.4
1.89
1.91
mu/l
0.10
486
4427
10
31
3.26
2.52
1.6
2.5
—
—
—
0
0
12
45
2.70
2.46
1.5
1.3
—
—
—
0
0
5
8
6.29
2.37
1.0
1.3
—
—
—
0
0
48
309
1.60
2.36
6.1
3.4
1.25
1.63
mmol/l
0.26
41
232
437
4029
1.31
2.29
6.1
4.5
14.86
14.72
pmol/l
0.55
415
3718
14
60
2.37
2.23
2.5
1.3
—
—
—
0
0
187
1554
1.30
2.22
4.5
3.2
0.00
0.02
estimate
1.46
68
449
33
196
1.72
2.20
1.8
1.6
—
—
—
0
0
12
48
2.53
2.19
1.4
1.2
—
—
—
0
0
12
48
2.53
2.19
1.4
1.2
—
—
—
0
0
8
24
3.36
2.18
1.1
1.3
—
—
—
0
0
9
30
3.03
2.15
2.3
3.8
1778.33
916.13
u/ml
—
9
30
10
37
2.73
2.08
1.4
1.8
—
—
—
0
0
5
10
5.03
2.07
2.2
1.3
—
—
—
0
0
22
118
1.90
2.04
1.6
1.3
3.69
3.67
mmol/l
0.02
22
111
9
32
2.84
2.00
1.6
1.8
—
—
—
0
0
9
32
2.84
2.00
1.6
1.7
—
—
—
0
0
22
119
1.88
1.99
1.4
1.4
—
—
—
0
0
557
5367
1.54
1.97
31.0
11.7
52.36
26.09
u/l
3.84
549
5231
8
27
2.99
1.94
1.1
1.7
—
—
—
0
0
6
16
3.78
1.94
1.3
1.6
167.67
73.06
nmol/24h
—
6
16
26
151
1.75
1.90
1.9
1.3
—
—
—
0
0
8
28
2.88
1.86
1.1
1.7
—
—
—
0
0
54
378
1.47
1.86
1.4
1.2
158.37
203.75
u/ml
0.33
48
348
41
271
1.55
1.84
1.2
1.3
—
—
—
0
0
5
12
4.19
1.82
1.2
1.2
—
—
—
0
0
29
178
1.66
1.76
2.4
1.6
—
—
—
0
0
7
24
2.94
1.72
2.1
2.0
45.21
72.98
ug/l
—
7
24
558
5397
1.50
1.72
41.0
19.5
79.27
76.07
umol/l
0.99
552
5342
23
134
1.75
1.68
1.7
1.4
518.26
479.25
mg/l
0.27
23
128
27
165
1.67
1.67
1.5
1.2
14.05
8.92
u/l
0.81
18
131
514
4909
1.33
1.67
30.5
14.4
81.89
82.16
ml/min/173m2
0.10
484
4548
6
20
3.02
1.58
1.0
1.2
—
—
—
0
0
7
26
2.71
1.58
2.1
1.7
—
—
—
0
0
7
26
2.71
1.58
2.1
1.7
—
—
—
0
0
7
26
2.71
1.58
2.1
1.7
—
—
—
0
0
7
26
2.71
1.58
2.1
1.7
—
—
—
0
0
53
383
1.42
1.58
1.2
1.3
209.29
136.69
u/ml
0.49
21
163
40
274
1.49
1.56
1.5
1.3
23.69
24.68
iu/l
0.08
30
235
30
193
1.58
1.54
1.9
1.1
0.94
0.90
g/l
0.36
30
193
8
33
2.44
1.54
1.1
1.6
—
—
—
0
0
250
2226
1.21
1.51
2.2
1.9
1.41
1.37
mmol/l
0.47
211
1905
6
21
2.88
1.51
1.0
1.4
—
—
—
0
0
6
21
2.88
1.51
1.2
1.0
—
—
—
0
0
55
404
1.40
1.50
1.6
1.4
—
—
—
0
0
20
117
1.73
1.46
1.8
1.3
17.15
12.52
e6/l
0.14
13
88
29
188
1.57
1.45
2.8
1.8
—
—
—
0
0
7
28
2.52
1.45
1.4
1.1
—
—
—
0
0
6
22
2.74
1.43
1.3
1.7
0.80
0.86
nmol/l
—
6
16
118
976
1.26
1.42
1.4
1.3
9.58
10.33
u/ml
0.05
44
377
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
29
2.43
1.39
1.3
1.2
—
—
—
0
0
20
119
1.70
1.39
1.8
1.4
213.29
136.10
e6/l
0.17
14
91
13
67
1.96
1.39
1.7
1.4
—
—
—
0
0
13
67
1.96
1.39
1.7
1.4
—
—
—
0
0
13
68
1.93
1.34
1.7
1.4
—
—
—
0
0
13
68
1.93
1.34
1.7
1.4
—
—
—
0
0
13
68
1.93
1.34
1.7
1.4
—
—
—
0
0
8
34
2.37
1.29
1.5
3.5
2378.00
756.91
mg
—
8
34
5
18
2.79
1.28
2.6
1.9
—
—
—
0
0
5
18
2.79
1.28
2.6
1.9
—
—
—
0
0
5
19
2.64
1.22
2.6
1.8
—
—
—
0
0
29
198
1.49
1.19
7.8
3.7
24.88
24.81
mmol/l
0.03
29
191
8
38
2.12
1.18
1.0
1.1
131.75
104.55
pmol/l
—
8
38
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
20
2.51
1.15
1.0
1.5
166.00
130.55
%
—
5
20
25
167
1.52
1.14
1.6
1.3
—
—
—
0
0
12
65
1.86
1.14
1.1
1.1
—
—
—
0
0
12
65
1.86
1.14
5.3
1.9
11.40
10.80
mmol/l
0.24
12
65
7
30
2.35
1.12
1.3
1.7
—
—
—
0
0
44
329
1.36
1.12
1.4
1.3
49.67
37.34
au/ml
—
7
27
14
81
1.75
1.09
1.6
1.8
—
—
—
0
0
8
41
1.96
1.09
1.3
1.1
275.12
216.86
mg/l
—
8
36
12
67
1.81
1.05
1.8
1.4
—
—
—
0
0
33
449
0.72
1.05
1.5
1.8
3.34
3.51
mmol/l
0.43
21
329
5
22
2.28
1.03
1.4
1.3
—
—
—
0
0
5
22
2.28
1.03
1.8
1.0
—
—
—
0
0
7
34
2.07
1.03
1.4
1.6
—
—
—
0
0
7
36
1.96
0.97
1.3
1.1
—
—
—
0
0
121
1047
1.20
0.97
1.4
1.3
37.37
31.27
iu/ml
0.29
34
326
9
52
1.74
0.92
1.1
1.1
—
—
—
0
0
23
159
1.46
0.92
1.2
1.3
—
—
—
0
0
6
28
2.15
0.91
1.8
1.1
—
—
—
0
0
21
143
1.49
0.91
1.8
1.4
38640.00
13329.24
e6/l
0.50
13
105
6
30
2.01
0.87
1.7
1.3
—
—
—
0
0
6
30
2.01
0.87
1.7
1.3
—
—
—
0
0
11
66
1.68
0.79
1.0
1.0
—
—
—
0
0
496
4814
1.18
0.78
8.0
6.2
39.79
39.11
mmol/mol
0.72
470
4548
15
100
1.51
0.73
2.8
2.7
6.39
8.35
pmol/l
0.60
15
100
5
25
2.01
0.73
1.6
1.2
—
—
—
0
0
5
25
2.01
0.73
1.6
1.2
—
—
—
0
0
7
39
1.80
0.72
1.9
1.3
—
—
—
0
0
5
26
1.93
0.70
1.6
1.9
2.02
8.67
nmol/l
—
5
21
50
604
0.81
0.70
1.9
2.0
3.32
3.51
ratio
0.52
38
483
503
4899
1.17
0.69
5.8
5.1
6.16
5.92
mmol/l
2.22
475
4535
19
138
1.39
0.63
1.4
1.3
—
—
—
0
0
44
363
1.23
0.61
2.6
2.5
29.10
18.57
au/ml
—
9
32
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
6
35
1.72
0.58
2.2
2.6
669.33
633.95
ml
—
6
20
6
35
1.72
0.58
1.2
1.1
—
—
—
0
0
6
37
1.63
0.55
1.0
1.3
—
—
—
0
0
9
62
1.46
0.53
1.2
1.1
—
—
—
0
0
110
1213
0.89
0.53
3.9
4.4
22.47
21.73
%
0.19
49
566
55
637
0.85
0.52
6.3
4.7
31.91
31.58
%
0.07
45
426
7
47
1.50
0.47
4.9
2.4
—
—
—
0
0
13
176
0.73
0.46
1.6
1.5
—
—
—
0
0
514
5048
1.13
0.45
6.1
5.1
4.63
4.68
mmol/l
0.43
490
4746
108
991
1.11
0.42
1.4
1.5
—
—
—
0
0
512
5034
1.12
0.41
5.9
5.0
1.46
1.48
mmol/l
0.39
486
4716
10
71
1.42
0.39
1.3
1.3
0.59
0.60
nmol/l
—
10
65
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
32
271
1.19
0.38
2.6
2.0
—
—
—
0
0
38
330
1.16
0.35
2.6
2.0
—
—
—
0
0
15
189
0.79
0.35
1.0
1.1
1.54
1.55
g/l
0.04
15
189
93
858
1.10
0.34
1.5
1.5
—
—
—
0
0
12
92
1.31
0.32
1.0
1.2
17.65
20.92
u/l
0.22
12
75
10
131
0.76
0.31
1.5
1.5
—
—
—
0
0
7
54
1.30
0.30
6.6
4.3
120.91
49.90
u/ml
—
7
54
559
5540
1.14
0.29
50.3
23.1
248.29
252.12
e9/l
0.65
547
5446
559
5541
1.13
0.29
50.0
23.0
91.72
91.06
fl
2.78
552
5495
8
63
1.27
0.28
1.0
1.1
106.75
99.98
%
—
8
57
559
5543
1.13
0.27
50.1
23.0
4.38
4.50
e12/l
5.60
547
5433
559
5543
1.13
0.27
51.5
23.4
39.61
40.46
%
3.69
552
5493
559
5545
1.12
0.26
50.5
23.2
131.72
135.55
g/l
6.92
552
5497
85
907
0.93
0.24
3.0
3.2
0.75
0.74
ug/l
0.05
54
560
143
1497
0.94
0.24
5.0
5.2
1.96
2.29
ug/l
0.49
133
1358
66
612
1.09
0.23
2.5
2.1
—
—
—
0
0
5
38
1.32
0.23
1.2
1.2
284.40
169.63
pmol/l
—
5
38
60
555
1.09
0.22
2.4
2.0
—
—
—
0
0
7
92
0.76
0.22
1.6
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
7.52
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
2.48
—
0
6
13
154
0.84
0.19
1.4
1.4
—
—
—
0
0
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
20
178
1.13
0.15
1.6
1.6
—
—
—
0
0
7
86
0.81
0.14
1.4
1.8
—
—
—
0
0
486
4818
1.05
0.14
5.2
4.3
1.36
1.28
mmol/l
1.51
457
4483
20
181
1.11
0.12
1.7
1.8
49.60
39.47
nmol/l
0.57
20
173
20
216
0.92
0.08
1.5
2.0
1.87
3.77
mg/l
1.41
15
164
61
588
1.04
0.08
12.0
7.0
—
—
—
0
0
5
64
0.78
0.08
1.0
1.2
—
—
—
0
0
6
70
0.86
0.07
1.7
1.4
6.63
7.48
mmol/l
—
6
61
6
75
0.80
0.07
1.2
1.4
—
—
—
0
0
9
84
1.07
0.07
1.0
1.1
—
—
—
0
0
27
284
0.95
0.06
1.0
1.0
—
—
—
0
0
15
140
1.07
0.04
1.6
1.8
177.60
219.02
pmol/l
1.18
15
131
19
180
1.06
0.04
2.3
1.8
—
—
—
0
0
513
5124
1.01
0.00
7.0
5.8
2.64
2.75
mmol/l
1.67
492
4805
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
5.97
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
59.90
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint K11_TOXLIV and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_TOXLIV | 2.305 [1.95, 2.72] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.287 |
During the follow-up period (1.1.1998 — 31.12.2019), 482 out of 1710 females with K11_TOXLIV died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_TOXLIV | 3.07 [2.52, 3.74] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.036 |
During the follow-up period (1.1.1998 — 31.12.2019), 519 out of 1402 males with K11_TOXLIV died.
Mortality risk
Mortality risk for people of age
years, who have K11_TOXLIV.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.296% | 0.643% |
| 5 | 1.451% | 3.723% |
| 10 | 3.399% | 8.851% |
| 15 | 6.4% | 17.475% |
| 20 | 11.149% | 28.193% |
Relationships between endpoints
↥Index endpoint: K11_TOXLIV – Toxic liver disease
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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