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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Toxic liver disease with cholestasis, drug-induced

TOXIC_LIVER_DISEA_W_CHOLESTA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs ANY
  • Hospital discharge: ICD-10 K71.0#

1 out of 7 registries used, show all original rules.

6

4. Check minimum number of events

None

6

5. Include endpoints

None

6

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 37.35 - -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
16
+∞
2.23
6.6
7.4
3.36
3.66
%
—
5
16
5
17
+∞
2.12
6.6
7.1
8.32
9.15
%
—
5
17
5
17
+∞
2.12
6.6
7.1
0.88
0.79
%
—
5
17
5
17
+∞
2.12
6.6
7.4
30.16
26.82
%
—
5
17
0
16
0.00
0.51
0.0
1.3
—
—
—
0
0
5
38
+∞
0.24
20.4
16.6
13.40
13.52
%
—
5
38
0
9
0.00
0.24
0.0
2.0
—
2.16
—
0
9
5
43
+∞
0.00
5.2
4.1
6.74
6.02
mmol/l
—
5
43
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
6.6
—
103.25
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
5
44
+∞
-0.00
11.4
15.3
3.98
4.00
mmol/l
—
5
44
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
5
44
+∞
-0.00
11.4
15.5
140.80
139.84
mmol/l
—
5
44
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
9.98
—
0
6
0
7
0.00
-0.00
0.0
2.1
—
25.03
—
0
7
5
44
+∞
-0.00
12.4
14.9
24.40
21.35
mg/l
—
5
38
5
44
+∞
-0.00
12.8
12.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
0.40
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
45
+∞
-0.00
20.6
18.9
89.20
81.87
umol/l
—
5
45
0
5
0.00
-0.00
0.0
4.0
—
96.14
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

Index endpoint: TOXIC_LIVER_DISEA_W_CHOLESTA – Toxic liver disease with cholestasis, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).