femoral neuropathy: Neuropathy of the femoral nerve.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
312 |
4. Check minimum number of eventsNone |
312 |
5. Include endpointsNone |
312 |
6. Filter based on genotype QC (FinnGen only) |
282 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G57
- Name in latin
- Morbositas nervi femoralis
Similar endpoints
↥List of similar endpoints to
Lesion of femoral nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1898 | 1197 | 693 |
| Only index persons | 1739 | 1132 | 607 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 52.40 | 52.31 | 52.41 |
| Only index persons | 51.40 | 51.82 | 50.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 282 | 208 | 74 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | 50.23 | 50.39 | 49.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 291
- Matched controls
- 2910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G57.2
ICD-10 Finland
Lesion of femoral nerve
4503599627370496.0
307.7
276
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
6.7
50.0
105
227
N03AX16
ATC
[U] pregabalin
5.8
48.3
133
368
N03AX12
ATC
[U] gabapentin; oral
6.1
45.6
105
246
G56.0
ICD-10 Finland
Carpal tunnel syndrome
11.4
44.3
50
52
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.0
37.0
80
174
M54.4
ICD-10 Finland
Lumbago with sciatica
4.6
33.3
108
328
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
172.8
30.3
31
*
N02AX02
ATC
tramadol; systemic, rectal
4.0
29.9
183
860
M48.0
ICD-10 Finland
Spinal stenosis
5.1
29.5
74
181
M54.1
ICD-10 Finland
Radiculopathy
8.9
26.6
35
44
N06AX21
ATC
duloxetine; oral
4.6
25.6
73
197
M54.5
ICD-10 Finland
Low back pain
3.5
24.2
159
752
N06AA09
ATC
amitriptyline; systemic
4.6
21.6
60
157
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.6
19.9
41
83
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.1
19.9
152
762
L86
ICPC
Back syndrome with radiating pain
5.4
19.6
42
88
G57.1
ICD-10 Finland
Meralgia paraesthetica
22.0
19.5
28
14
M54.3
ICD-10 Finland
Sciatica
6.0
19.1
36
67
M70.6
ICD-10 Finland
Trochanteric bursitis
3.6
18.9
77
264
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.7
18.5
72
239
M79.6
ICD-10 Finland
Pain in limb
3.0
18.1
175
982
XA402
NOMESCO Finland
ENMG
14.4
17.9
30
23
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.0
17.7
41
92
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.0
16.4
53
154
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.7
16.2
27
44
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.4
15.9
44
114
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.6
15.8
61
200
ACC51
NOMESCO Finland
Release of median nerve
168.7
15.6
16
*
M01AX17
ATC
nimesulide; oral
2.9
15.6
100
444
N02BF01
ATC
gabapentin; oral
3.9
15.5
51
150
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.8
14.8
111
533
L01
ICPC
Neck symptom/complaint
3.2
14.8
73
279
3552A
ICD-9 Finland
Mononeuritis of lower limb, Other lesion of femoral nerve
+∞
14.7
14
*
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
6.4
14.6
25
42
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.7
13.5
105
509
M47.82
ICD-10 Finland
Other spondylosis, cervical region
5.4
13.2
27
54
L14
ICPC
Leg/thigh symptom/complaint
3.8
13.1
44
131
L13
ICPC
Hip symptom/complaint
2.7
13.1
90
410
M03BX02
ATC
tizanidine; oral
2.7
13.0
216
1489
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.3
12.9
27
55
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.9
12.8
24
44
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
73.1
12.7
14
*
L03
ICPC
Low back symptom/complaint
2.5
12.7
112
575
SPAT1216
SPAT
Assessment of functional ability
3.1
12.7
62
234
N02AA05
ATC
oxycodone; systemic
2.9
12.6
70
284
SPAT1249
SPAT
Treatment-related counselling outside office
2.4
11.9
135
773
N06AX11
ATC
mirtazapine; oral
2.4
11.8
127
710
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.7
11.5
22
41
M25.5
ICD-10 Finland
Pain in joint
2.4
11.5
126
707
G57.0
ICD-10 Finland
Lesion of sciatic nerve
124.7
11.5
12
*
A02BC05
ATC
esomeprazole; systemic
2.3
11.3
146
879
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
11.2
83
389
H02AB06
ATC
prednisolone; systemic
2.3
11.0
163
1034
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.9
10.8
34
96
A02BA02
ATC
ranitidine; systemic
2.6
10.7
73
327
A02BC02
ATC
pantoprazole; systemic
2.6
10.7
225
1654
R52.9
ICD-10 Finland
Pain, unspecified
3.1
10.7
50
183
N02BF02
ATC
pregabalin; oral
3.9
10.5
33
93
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
10.5
33
93
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.5
10.3
26
62
M03BC01
ATC
orphenadrine (citrate); systemic
2.4
10.3
89
446
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
10.2
99
523
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
41.6
10.0
12
*
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
5.2
9.9
21
43
R52.2
ICD-10 Finland
Other chronic pain
5.0
9.9
22
47
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
5.6
9.8
19
36
L17
ICPC
Foot/toe symptom/complaint
2.3
9.8
112
632
A02BC03
ATC
lansoprazole; oral
2.3
9.6
104
572
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.0
9.6
28
75
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
9.5
53
213
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
103.3
9.5
10
*
N03AE01
ATC
clonazepam; systemic
4.1
9.5
27
71
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.2
9.5
20
41
M79.7
ICD-10 Finland
Fibromyalgia
5.2
9.5
20
41
M03BC51
ATC
orphenadrine, combinations; systemic
2.2
9.4
107
600
R10.0
ICD-10 Finland
Acute abdomen
7.5
9.2
21
30
G44.2
ICD-10 Finland
Tension-type headache
2.6
9.1
59
256
SPAT1263
SPAT
Sampling
2.1
9.1
132
813
SPAT1153
SPAT
Removal of sutures
2.2
9.1
104
584
NF1AA
NOMESCO Finland
Hip X-ray examination
3.2
8.9
37
126
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.8
8.8
50
203
G57.6
ICD-10 Finland
Lesion of plantar nerve
14.6
8.8
14
10
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
8.6
41
151
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.5
8.6
21
49
SPAT1310
SPAT
Counselling related to known health issue
2.1
8.5
109
636
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
8.5
143
925
N05AH04
ATC
quetiapine; oral
2.5
8.5
63
292
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
8.5
145
944
AA1AD
NOMESCO Finland
CT of head and brain
2.2
8.3
97
545
R5599
NOMESCO Finland
Other rehabilitation service
7.9
8.3
18
24
J02AC01
ATC
fluconazole; systemic
2.0
8.2
145
950
M01AH01
ATC
celecoxib; oral
2.4
8.2
68
332
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
8.1
42
162
M47.9
ICD-10 Finland
Spondylosis, unspecified
7.6
8.1
18
25
L08
ICPC
Shoulder symptom/complaint
2.2
8.1
83
443
RD211, ,
NOMESCO Finland
3.8
8.0
25
70
WZC30
NOMESCO Finland
Teaching
2.4
8.0
65
313
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
7.3
7.9
18
26
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.7
7.8
47
196
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
7.8
75
388
M01AB05
ATC
diclofenac; systemic, rectal
2.2
7.8
211
1603
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.8
7.8
24
67
SPAT1229
SPAT
Assessment of need for aid
3.4
7.6
29
93
G54.0
ICD-10 Finland
Brachial plexus disorders
25.8
7.6
10
*
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.6
7.5
18
41
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
82.1
7.5
8
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.0
7.4
177
1274
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
7.4
46
195
WZC00, ,
SPAT
2.4
7.3
57
269
G58.9
ICD-10 Finland
Mononeuropathy, unspecified
+∞
7.3
7
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
7.3
148
1006
SPAT1252
SPAT
Overall medication plan or its review
3.5
7.3
26
80
R42
ICD-10 Finland
Dizziness and giddiness
2.1
7.2
80
437
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
7.2
38
148
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
7.1
122
782
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
6.1
7.0
18
31
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.2
7.0
29
98
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
7.0
65
331
M01AC06
ATC
meloxicam; systemic, rectal
1.9
6.9
126
822
M54
ICD-10 Finland
Dorsalgia
2.6
6.9
42
176
J01AA02
ATC
doxycycline; systemic
2.4
6.9
244
2002
M77.1
ICD-10 Finland
Lateral epicondylitis
3.0
6.9
32
116
M01AH03
ATC
valdecoxib; oral
3.6
6.8
23
68
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
3.6
6.8
23
68
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
7.5
6.8
15
21
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
41.0
6.8
8
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
6.7
80
448
L02
ICPC
Back symptom/complaint
2.5
6.7
44
191
R4110, ,
SPAT
2.3
6.7
54
258
N06AX16
ATC
venlafaxine; oral
2.3
6.7
55
265
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
23.1
6.7
9
*
M01AH02
ATC
rofecoxib; oral
2.5
6.6
46
206
M79.1
ICD-10 Finland
Myalgia
2.2
6.5
60
304
D02
ICPC
Abdominal pain epigastric
3.0
6.5
29
103
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
4.2
6.4
17
42
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.8
6.4
15
23
J01CA04
ATC
amoxicillin; systemic
2.3
6.4
244
2022
SAA01
NOMESCO Finland
Simple examination of mouth
2.1
6.4
223
1786
D06
ICPC
Abdominal pain localized other
2.8
6.4
33
127
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
6.3
117
763
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
6.3
45
204
35399
ICD-8 Finland
Sciatica
+∞
6.3
6
*
TAB00
NOMESCO Finland
Lumbar puncture
3.6
6.3
21
62
M89.0
ICD-10 Finland
Algoneurodystrophy
27.3
6.3
8
*
N05CF01
ATC
zopiclone; oral
1.9
6.3
107
679
X58
ICD-10 Finland
Exposure to other specified factors
2.3
6.3
52
252
UJF32
NOMESCO Finland
Coloscopy
2.0
6.2
83
483
SPAT1359
SPAT
Use of symptom diary
6.0
6.2
16
28
M01AB55
ATC
diclofenac, combinations; oral
3.1
6.2
27
94
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.9
6.2
13
17
-1, ,
ICPC
3.8
6.1
19
53
EB1VA, ,
NOMESCO Finland
2.1
6.1
68
370
KHV, ,
NOMESCO Finland
12.9
6.1
10
8
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
12.9
6.1
10
8
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
6.1
58
297
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.8
6.1
143
1001
M01AH05
ATC
etoricoxib; oral
1.9
6.1
199
1545
R06AX27
ATC
desloratadine; oral
1.9
6.1
96
593
M01AB08
ATC
etodolac; oral
2.8
6.0
30
113
A01AB09
ATC
miconazole; local oral
2.7
6.0
33
131
SPAT1260
SPAT
Consultation of another employee
2.2
6.0
60
313
R06AE09
ATC
levocetirizine; oral
2.3
6.0
50
242
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
6.0
91
553
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
128
809
2.04
7.97
3.4
2.4
58.03
69.70
u/l
0.70
117
744
122
761
2.04
7.85
4.7
3.8
0.00
0.01
estimate
0.50
65
274
214
1657
2.10
7.21
5.1
4.3
—
165.17
—
0
30
250
2069
2.48
6.99
6.5
4.4
14.97
14.79
pmol/l
0.53
244
1908
142
963
1.93
6.96
4.1
3.5
20.95
91.55
ng/l
0.61
88
658
150
1046
1.90
6.66
3.9
3.6
0.00
0.03
estimate
1.15
53
240
185
1386
1.92
6.53
4.3
3.8
18.61
6.30
estimate
0.27
67
298
186
1406
1.89
6.27
4.3
3.8
0.00
1.09
estimate
0.51
63
282
118
781
1.86
6.00
3.0
3.2
0.35
0.11
estimate
0.29
57
235
182
1382
1.85
5.88
4.4
3.8
0.00
0.00
estimate
-0.00
65
291
101
647
1.86
5.63
2.1
2.0
2.62
2.76
mg/l
0.41
90
560
173
1316
1.78
5.33
7.2
6.8
1.21
1.22
mmol/l
0.38
160
1135
80
483
1.91
5.32
1.3
1.3
6.89
13.21
u/ml
0.79
34
197
12
19
6.54
5.13
2.7
1.4
—
—
—
0
0
152
1131
1.72
4.91
4.0
4.6
36.07
36.21
g/l
0.13
143
1065
106
739
1.68
4.20
2.9
3.1
819.69
909.11
ng/l
0.18
92
625
16
52
3.20
4.15
1.8
2.7
8.08
7.96
kpa
0.11
16
52
160
1244
1.64
4.10
2.7
2.4
78.58
79.38
nmol/l
0.14
152
1130
188
1525
1.66
4.05
10.3
10.3
3.86
3.96
e9/l
0.26
165
1321
268
2426
2.32
3.85
7.6
5.4
1.72
1.89
mu/l
2.10
257
2239
123
910
1.61
3.77
3.4
3.0
—
—
—
0
0
12
29
4.27
3.75
1.0
2.0
1.73
1.54
mmol/l
0.50
12
29
91
626
1.66
3.72
1.4
1.2
1.13
1.54
u/ml
0.26
36
171
80
533
1.69
3.69
1.4
1.3
20.55
37.17
iu/ml
1.33
26
160
102
724
1.63
3.68
3.0
3.0
0.21
0.40
e6/l
1.12
86
510
65
412
1.74
3.58
2.2
2.1
14.11
13.49
umol/l
0.31
59
385
13
37
3.63
3.45
1.9
2.6
17.12
15.82
%
0.96
13
37
17
65
2.72
3.37
1.1
1.2
472.24
492.02
mg/l
0.13
17
60
76
513
1.65
3.31
2.0
1.6
434.15
27660028.43
pmol/l
0.50
68
423
15
54
2.87
3.30
1.3
1.5
—
—
—
0
0
230
2009
1.69
3.30
10.3
8.1
76.42
77.94
u/l
0.32
224
1910
18
72
2.60
3.28
1.3
1.4
1.22
1.20
g/l
0.10
18
67
57
357
1.74
3.26
2.1
2.1
23.50
22.59
%
0.21
50
337
45
263
1.84
3.24
5.7
9.9
1.13
1.16
mmol/l
0.03
36
228
45
264
1.83
3.20
5.8
9.9
11.59
12.50
kpa
0.81
45
259
45
264
1.83
3.20
5.8
10.0
4.99
5.19
kpa
0.90
45
258
154
1237
1.52
3.10
3.5
2.9
107.67
108.33
ug/l
0.02
143
1153
60
387
1.69
3.09
2.3
2.1
2.31
2.36
g/l
0.28
54
361
170
1398
1.52
3.04
7.4
6.7
9.73
10.76
umol/l
1.15
163
1335
11
32
3.53
2.93
1.4
1.7
—
—
—
0
0
10
27
3.80
2.91
1.1
1.0
—
—
—
0
0
17
71
2.48
2.86
4.5
2.7
—
—
—
0
0
17
71
2.48
2.86
1.6
3.0
24.47
25.27
mmol/l
0.53
17
71
68
464
1.61
2.80
1.5
1.5
—
—
—
0
0
144
1163
1.47
2.69
3.0
2.6
—
—
estimate
—
0
0
12
43
2.87
2.68
1.4
1.6
—
—
—
0
0
13
49
2.73
2.66
2.1
1.9
135.92
128.85
g/l
0.62
13
34
12
44
2.80
2.58
1.4
1.5
—
—
—
0
0
30
166
1.90
2.56
1.6
1.7
—
—
—
0
0
81
587
1.53
2.56
1.8
1.6
1.35
1.03
mg/l
0.52
66
470
5
7
7.24
2.56
1.6
1.1
—
—
—
0
0
58
393
1.59
2.45
1.7
1.6
1275.02
1223.30
nmol/l
0.20
47
288
85
631
1.49
2.38
2.5
2.6
329.24
336.74
umol/l
0.30
74
569
141
1158
1.42
2.30
2.0
2.0
94.79
98.09
pmol/l
0.30
77
566
51
344
1.59
2.20
5.1
6.8
104.73
104.26
mmol/l
0.21
51
344
13
55
2.43
2.15
1.1
1.1
3.61
3.88
mmol/l
0.59
13
49
180
1557
1.41
2.11
2.8
2.9
—
—
—
0
0
117
941
1.41
2.10
2.2
3.4
2.35
2.36
mmol/l
0.85
110
866
5
10
5.07
2.08
1.4
1.5
—
—
—
0
0
5
10
5.07
2.08
1.4
1.6
—
—
—
0
0
17
83
2.11
2.05
1.7
1.3
289.45
273.32
ug/g
0.12
11
41
6
15
4.06
2.05
1.0
1.0
—
—
—
0
0
76
569
1.45
2.01
4.6
3.8
1.02
1.02
kg/l
0.16
54
377
14
64
2.25
1.97
2.1
1.4
—
—
—
0
0
21
113
1.93
1.97
2.1
1.5
3.08
3.22
iu/ml
—
10
25
5
11
4.60
1.95
1.4
1.6
—
—
—
0
0
16
80
2.06
1.83
1.9
2.1
—
—
—
0
0
7
23
3.09
1.81
1.0
1.2
107.00
106.22
pmol/l
—
7
23
275
2617
1.92
1.80
22.2
16.7
139.66
139.86
mmol/l
0.65
270
2565
275
2618
1.92
1.78
22.1
16.8
3.99
3.96
mmol/l
1.03
270
2559
6
18
3.38
1.75
1.5
1.1
—
—
—
0
0
6
18
3.38
1.75
1.5
1.1
—
—
—
0
0
11
48
2.34
1.72
2.7
1.4
—
—
—
0
0
54
391
1.47
1.69
2.1
1.9
—
—
—
0
0
6
19
3.20
1.67
1.0
1.1
—
—
—
0
0
43
298
1.52
1.66
1.9
1.8
—
—
—
0
0
10
41
2.49
1.66
1.2
1.4
—
—
—
0
0
266
2518
1.66
1.63
20.7
14.1
19.62
22.35
mg/l
0.73
240
2032
41
288
1.49
1.49
1.8
1.8
—
—
—
0
0
9
37
2.48
1.49
1.3
2.0
—
—
—
0
0
6
22
2.76
1.44
1.2
1.9
—
—
—
0
0
13
67
1.98
1.40
2.3
1.8
3.37
4.02
iu/l
—
5
24
6
24
2.53
1.31
1.0
1.2
—
—
—
0
0
24
154
1.61
1.30
2.0
2.8
92.77
166.73
ng/l
1.73
24
143
36
254
1.48
1.30
4.5
3.2
—
—
—
0
0
271
2598
1.63
1.29
5.7
5.1
4.72
4.78
mmol/l
0.50
261
2427
270
2588
1.60
1.27
5.5
5.0
1.52
1.53
mmol/l
0.10
258
2404
14
78
1.84
1.23
1.7
1.9
—
—
—
0
0
136
1189
1.27
1.22
2.1
1.9
1.46
1.35
mmol/l
0.72
109
999
16
94
1.74
1.20
1.7
1.6
—
—
—
0
0
6
26
2.33
1.19
1.0
1.2
—
—
—
0
0
32
225
1.47
1.18
2.8
2.7
66.36
64.45
ml/min/173m2
0.16
14
93
27
183
1.52
1.18
1.3
1.2
165.63
148.89
u/ml
—
10
84
263
2519
1.46
1.09
18.8
14.4
80.35
80.94
ml/min/173m2
0.19
252
2334
13
74
1.79
1.08
1.4
1.3
—
—
—
0
0
259
2482
1.40
0.99
6.6
6.0
40.10
38.82
mmol/mol
1.63
248
2336
14
85
1.68
0.96
2.0
1.8
0.84
4.54
ug/l
0.61
14
78
9
51
1.79
0.95
2.2
2.7
6.71
7.58
pmol/l
—
9
51
37
281
1.36
0.93
7.1
6.2
—
—
—
0
0
6
28
2.17
0.92
1.5
1.6
—
—
—
0
0
6
28
2.17
0.92
3.3
2.5
3.15
3.36
nmol/l
—
6
28
17
111
1.56
0.90
1.2
1.5
—
—
—
0
0
8
43
1.88
0.88
1.1
1.1
—
12.29
—
0
12
6
30
2.02
0.87
1.3
1.5
—
—
—
0
0
257
2472
1.34
0.84
4.7
4.3
1.29
1.28
mmol/l
0.17
246
2288
0
27
0.00
0.78
0.0
1.2
—
—
—
0
0
271
2635
1.41
0.75
6.4
5.9
2.71
2.80
mmol/l
1.01
257
2458
87
760
1.21
0.73
1.8
1.6
19.12
21.34
nmol/l
0.78
78
639
282
2766
1.63
0.71
30.6
22.3
4.43
4.48
e12/l
1.16
277
2714
99
879
1.19
0.70
4.2
3.7
5.90
6.65
mg/mmol
0.15
71
511
261
2531
1.30
0.66
5.4
5.0
5.96
5.88
mmol/l
0.36
247
2341
11
70
1.59
0.66
1.3
3.8
1.23
2.23
ratio
—
6
44
56
475
1.22
0.63
4.3
3.7
64.53
263.41
ng/l
1.32
40
361
21
156
1.37
0.63
1.7
1.6
—
—
—
0
0
29
227
1.31
0.63
1.9
1.8
—
—
—
0
0
6
105
0.56
0.63
1.2
1.2
0.88
0.92
g/l
—
6
105
12
80
1.52
0.60
1.9
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
27
212
1.30
0.58
1.3
1.4
—
—
—
0
0
17
124
1.39
0.57
1.4
1.4
26.16
30.05
iu/l
0.17
17
106
6
37
1.63
0.56
6.8
3.1
14.22
22.13
u/ml
—
6
37
6
100
0.59
0.52
1.2
1.1
1.78
1.58
g/l
—
6
100
26
207
1.28
0.51
1.7
1.8
—
—
—
0
0
69
617
1.16
0.45
3.0
2.1
—
—
—
0
0
11
78
1.43
0.43
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.41
0.41
1.2
1.2
73.60
196.74
miu/ml
—
5
37
5
34
1.48
0.40
1.8
1.6
—
—
—
0
0
101
934
1.12
0.40
3.8
3.0
29.63
29.11
u/l
0.12
95
881
0
18
0.00
0.40
0.0
2.2
—
—
—
0
0
25
301
0.81
0.40
2.6
2.1
3.51
3.39
ratio
0.17
18
248
5
35
1.44
0.39
1.0
1.1
—
1.44
—
0
10
9
66
1.38
0.38
1.3
1.5
—
—
—
0
0
9
68
1.33
0.38
1.3
1.7
—
—
—
0
0
25
212
1.20
0.31
2.4
2.5
4.45
4.39
kpa
0.05
25
207
17
138
1.25
0.31
1.2
1.1
—
—
—
0
0
45
403
1.14
0.30
4.4
4.2
24.28
22.66
%
0.29
28
179
17
139
1.24
0.29
2.9
2.3
0.71
0.62
%
0.33
17
139
7
57
1.23
0.29
1.0
1.1
—
9.82
—
0
9
13
103
1.27
0.28
1.5
1.5
—
—
—
0
0
8
62
1.30
0.28
2.1
1.3
—
—
—
0
0
17
140
1.23
0.28
2.9
2.4
1.28
1.22
%
0.11
17
140
15
122
1.24
0.27
1.8
1.4
—
—
—
0
0
48
438
1.11
0.24
3.4
2.8
0.72
0.99
e6/l
0.59
31
213
53
487
1.11
0.24
1.7
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
46.01
—
0
12
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
0.64
—
0
9
6
49
1.23
0.20
1.2
1.3
—
—
—
0
0
20
226
0.88
0.18
2.3
1.9
3.31
3.51
mmol/l
0.38
15
174
9
83
1.09
0.15
1.1
1.3
—
—
—
0
0
7
86
0.81
0.15
1.1
1.1
—
—
—
0
0
21
233
0.89
0.14
2.3
3.2
1.66
2.27
mmol/l
0.52
21
210
33
305
1.09
0.14
2.7
4.6
3.89
7.30
ug/l
0.98
24
248
12
137
0.87
0.12
1.5
1.3
—
—
—
0
0
7
64
1.10
0.08
1.4
1.3
—
0.92
—
0
5
7
65
1.08
0.08
1.1
1.2
—
—
—
0
0
8
74
1.08
0.07
2.0
1.2
—
—
—
0
0
8
77
1.04
0.07
3.3
2.0
305.05
247.93
ug/l
—
8
72
7
80
0.87
0.07
1.4
1.2
—
—
—
0
0
7
85
0.82
0.07
1.1
1.1
—
—
—
0
0
32
307
1.05
0.05
3.0
3.0
0.71
0.70
ug/l
0.03
23
200
30
289
1.04
0.04
1.6
1.8
1.40
1.39
%
0.05
30
254
40
411
0.97
0.03
3.9
2.9
1.99
2.72
e6/l
0.39
23
185
14
134
1.05
0.00
2.1
3.4
24.71
24.62
mmol/l
0.05
14
134
10
101
0.99
0.00
1.1
1.7
—
—
—
0
0
12
115
1.05
0.00
1.3
1.8
—
—
—
0
0
181
1807
1.00
0.00
4.0
3.1
57.60
44.08
u/l
0.76
176
1707
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
128.50
—
0
6
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
106.67
—
0
9
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
1.20
—
0
6
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
9
0.00
0.00
0.0
2.3
—
100.78
—
0
9
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.8
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
-0.00
0.0
1.0
—
132.86
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
6.89
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint G6_FEMLE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 0.953 [0.78, 1.16] | 0.637 |
| Birth year | 0.996 [0.99, 1.0] | 0.355 |
During the follow-up period (1.1.1998 — 31.12.2019), 114 out of 1038 females with G6_FEMLE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 1.514 [1.24, 1.85] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 596 males with G6_FEMLE died.
Mortality risk
Mortality risk for people of age
years, who have G6_FEMLE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.246% |
| 5 | 0.603% | 1.748% |
| 10 | 1.412% | 4.45% |
| 15 | 2.804% | 8.239% |
| 20 | 5.006% | 13.697% |
Relationships between endpoints
↥Index endpoint: G6_FEMLE – Lesion of femoral nerve
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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