No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
69 |
4. Check minimum number of eventsNone |
69 |
5. Include endpointsNone |
69 |
6. Filter based on genotype QC (FinnGen only) |
63 |
Control definitions (FinnGen only)
- Control exclude
- H7_OPTNERVE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H47
- Name in latin
- Morbositas partis non specificatae tractuum opticorum
Similar endpoints
↥List of similar endpoints to
Disorder of visual pathways, unspecified
based on the number of shared cases.
Similar with more cases:
- Other disorders of optic [2nd] nerve and visual pathways
- Disorders of optic nerve and visual pathways
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 537 | 259 | 275 |
| Only index persons | 443 | 214 | 229 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 18.91 | 22.93 | 14.70 |
| Only index persons | 24.82 | 34.55 | 15.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 63 | 35 | 28 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 48.21 | 50.88 | 44.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 66
- Matched controls
- 660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
89.4
64
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
10.2
19.3
30
50
Z3229
NOMESCO Finland
Other healthcare associate professional
8.4
15.5
27
50
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
43.5
11.8
14
*
H47.2
ICD-10 Finland
Optic atrophy
+∞
11.8
11
*
RT274, ,
NOMESCO Finland
+∞
10.7
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.2
10.7
24
56
P85
ICPC
Mental retardation
64.9
10.0
11
*
H54.7
ICD-10 Finland
Unspecified visual loss
116.0
9.7
10
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
9.6
9
*
N05BA09
ATC
clobazam; oral
43.2
9.3
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.9
8.8
19
42
XCK00
NOMESCO Finland
Perimetry
11.3
8.6
16
18
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
8.5
8
*
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
8.5
8
*
M03BX01
ATC
baclofen; systemic
38.6
8.3
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
8.1
29
98
RL140, ,
NOMESCO Finland
18.5
7.5
11
7
N03AG04
ATC
vigabatrin; oral
+∞
7.4
7
*
RT190, ,
NOMESCO Finland
+∞
7.4
7
*
RS142, ,
NOMESCO Finland
+∞
7.4
7
*
N05CD08
ATC
midazolam; nasal, systemic
16.1
7.2
11
8
Z2446
NOMESCO Finland
Social worker
4.5
7.0
22
66
RT160, ,
NOMESCO Finland
25.6
6.9
9
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
6.6
6.6
17
33
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
77.0
6.5
7
*
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
77.0
6.5
7
*
RT490, ,
NOMESCO Finland
77.0
6.5
7
*
H53.4
ICD-10 Finland
Visual field defects
29.8
6.4
8
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
6.3
6
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
6.3
6
*
G80.8
ICD-10 Finland
Other cerebral palsy
+∞
6.3
6
*
3AX01, ,
NOMESCO Finland
+∞
6.3
6
*
R4110
NOMESCO Finland
Physiotherapy
3.6
6.1
35
158
XCD10
NOMESCO Finland
Electrophysiological examination of eye
12.8
6.0
10
9
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
12.8
6.0
10
9
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
340
2.94
3.56
12.5
11.2
1.21
1.22
mmol/l
0.37
44
297
34
195
2.53
3.37
2.9
4.3
0.71
0.30
e6/l
0.37
28
144
22
104
2.67
3.21
19.4
19.7
24.73
25.07
mmol/l
0.12
22
104
19
84
2.77
3.14
12.6
14.9
105.84
103.79
mmol/l
1.11
19
84
20
98
2.49
2.67
4.5
12.8
24.20
23.52
mmol/l
0.36
20
98
14
57
2.85
2.66
15.6
24.2
1.21
1.36
mmol/l
0.18
14
57
10
38
2.92
2.11
21.8
22.9
22.78
24.28
mmol/l
—
10
38
43
320
1.99
1.85
4.9
4.1
0.00
0.00
estimate
-0.00
11
64
43
321
1.97
1.82
5.7
4.2
0.18
0.00
estimate
0.47
11
67
43
323
1.95
1.76
5.8
4.2
0.00
0.00
estimate
—
9
62
5
13
4.07
1.75
1.0
1.5
—
—
—
0
0
5
13
4.07
1.75
1.0
1.5
—
—
—
0
0
6
19
3.36
1.70
1.3
2.9
2317.83
320.68
mg/l
—
6
19
21
126
1.98
1.66
2.9
4.1
1.43
0.62
e6/l
0.76
12
73
5
15
3.51
1.55
1.4
3.2
3.48
3.71
mmol/l
—
5
15
6
23
2.76
1.40
4.0
1.4
54.17
39.19
u/l
—
6
18
5
17
3.09
1.38
1.0
1.8
—
—
—
0
0
6
25
2.54
1.27
1.0
1.1
—
—
—
0
0
20
137
1.66
0.99
6.8
3.8
1.01
1.02
kg/l
0.93
14
82
0
31
0.00
0.99
0.0
1.8
—
—
—
0
0
0
31
0.00
0.99
0.0
1.8
—
223.73
—
0
11
23
164
1.62
0.98
4.7
3.8
0.00
0.00
estimate
—
10
63
56
496
1.85
0.97
27.9
22.2
330.53
333.47
g/l
1.16
56
496
18
121
1.67
0.96
2.8
4.2
1.84
1.58
e6/l
—
9
68
6
28
2.25
0.94
3.0
5.8
30.17
27.40
nmol/l
—
6
28
9
147
0.55
0.93
2.1
3.5
298.33
326.54
umol/l
—
9
125
29
223
1.54
0.89
1.9
2.2
102.64
96.39
pmol/l
0.27
17
107
45
384
1.54
0.83
6.8
11.8
4.63
4.03
e9/l
0.66
40
332
0
26
0.00
0.80
0.0
2.4
—
84.82
—
0
11
28
224
1.43
0.67
5.3
3.9
0.33
0.00
estimate
—
9
57
11
71
1.66
0.67
2.0
1.9
—
—
—
0
0
8
50
1.68
0.64
1.3
1.2
—
151.02
—
0
13
0
19
0.00
0.61
0.0
1.8
—
306.96
—
0
9
0
19
0.00
0.61
0.0
1.6
—
7.43
—
0
19
0
19
0.00
0.61
0.0
1.6
—
4.37
—
0
19
0
19
0.00
0.61
0.0
1.6
—
3.42
—
0
19
12
83
1.54
0.56
2.4
2.4
398.25
388.03
nmol/l
0.06
12
78
34
289
1.36
0.55
3.0
2.9
—
—
estimate
—
0
0
6
39
1.59
0.54
2.2
1.6
—
—
—
0
0
12
161
0.69
0.48
2.8
1.9
—
—
—
0
0
7
49
1.48
0.48
18.1
7.5
—
—
—
0
0
37
415
0.75
0.47
4.1
3.3
—
—
—
0
0
16
200
0.74
0.43
1.6
3.5
2.43
2.38
mmol/l
0.84
16
185
0
15
0.00
0.42
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
10.71
—
0
16
5
34
1.51
0.41
1.6
2.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
2.95
—
0
17
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
49
452
1.33
0.39
16.0
15.3
81.49
83.31
ml/min/173m2
0.18
41
399
16
128
1.33
0.36
5.3
11.6
1.04
1.23
mmol/l
2.05
16
121
6
44
1.40
0.35
2.5
12.7
1.38
1.33
%
—
6
44
10
74
1.41
0.34
2.0
1.8
—
—
—
0
0
47
501
0.79
0.31
5.4
4.8
6.06
5.83
mmol/l
0.62
47
464
22
194
1.20
0.22
3.4
3.7
24.18
44.10
ng/l
0.88
13
134
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
87.90
—
0
10
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
0.00
—
0
13
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
1.71
—
0
5
19
168
1.18
0.18
2.3
2.7
—
—
—
0
0
12
101
1.23
0.18
2.7
1.8
—
—
—
0
0
5
65
0.75
0.18
1.6
1.3
—
—
—
0
0
18
164
1.13
0.11
4.6
3.6
0.00
0.00
estimate
—
7
51
6
58
1.04
0.08
1.3
1.4
—
—
—
0
0
36
367
0.96
0.01
3.8
4.6
52.28
45.59
u/l
0.27
36
350
0
8
0.00
0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
101.40
—
0
5
0
5
0.00
0.00
0.0
2.0
—
28.52
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
89.67
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
164.57
—
0
7
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
52.88
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
301.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
106.57
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint H7_VISUALPATHNAS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H7_VISUALPATHNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H7_VISUALPATHNAS – Disorder of visual pathways, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data