muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
407 |
4. Check minimum number of eventsNone |
407 |
5. Include endpointsNone |
407 |
6. Filter based on genotype QC (FinnGen only) |
379 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M79
- Name in latin
- Hypertrophia corporis adiposi infrapatellaris
Similar endpoints
↥List of similar endpoints to
Hypertrophy of (infrapatellar) fat pad
based on the number of shared cases.
Similar with more cases:
- Other soft tissue disorders, not elsewhere classified
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2650 | 1415 | 1223 |
| Only index persons | 2524 | 1364 | 1160 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.05 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 38.04 | 39.91 | 35.86 |
| Only index persons | 37.48 | 39.43 | 35.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 379 | 229 | 150 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.07 |
| Median age at first event (years) | 37.72 | 36.24 | 39.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 389
- Matched controls
- 3890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M79.4
ICD-10 Finland
Hypertrophy of (infrapatellar) fat pad
+∞
307.7
269
*
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
74.8
142.9
78
13
7293A
ICD-9 Finland
Other disorders of soft tissues, Panniculitis, unspecified[LIPOSYNOVITIS INFRAPATELLARIS (MORBUS HOFFA)]
+∞
134.4
121
*
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
17.6
113.7
103
78
1225
FHL
Arthroscopy and other therapeutic procedure
30.3
71.0
48
18
M23.8
ICD-10 Finland
Other internal derangements of knee
14.9
63.7
60
47
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
14.5
54.8
52
41
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
6.6
53.4
104
205
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
5.6
40.7
90
197
1220
FHL
Arthroscopy
10.7
39.3
45
47
M79.6
ICD-10 Finland
Pain in limb
3.7
36.4
207
908
M25.5
ICD-10 Finland
Pain in joint
3.6
33.8
181
756
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.2
33.7
115
354
ZXE00
NOMESCO Finland
One hour or less
3.4
32.0
205
951
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
6.3
31.4
58
106
N02AX02
ATC
tramadol; systemic, rectal
3.3
29.7
196
915
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.3
29.6
218
1085
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.9
29.3
110
359
N03AX16
ATC
[U] pregabalin
3.7
28.4
113
383
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.3
26.0
133
526
1221
FHL
Arthroscopy and meniscus surgery
11.1
25.6
28
27
M01AH05
ATC
etoricoxib; oral
3.4
25.5
291
1808
S83.2
ICD-10 Finland
Tear of meniscus, current
5.3
24.7
54
115
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
7.5
24.6
37
54
1222
FHL
Arthroscopy and synovial surgery
36.0
23.7
30
9
WX320
NOMESCO Finland
Spinalanesthesy
3.2
23.0
122
488
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.9
22.9
79
240
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
6.6
22.5
38
63
M22.4
ICD-10 Finland
Chondromalacia patellae
8.5
22.4
30
38
SPAT1153
SPAT
Removal of sutures
2.9
21.7
146
665
SPAT1249
SPAT
Treatment-related counselling outside office
2.8
21.6
186
964
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
36.1
21.4
27
8
N06AX21
ATC
duloxetine; oral
3.9
20.1
66
193
M79.0
ICD-10 Finland
Rheumatism, unspecified
77.3
19.9
22
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
8.2
19.8
27
35
M01AB05
ATC
diclofenac; systemic, rectal
2.9
19.3
291
1959
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
19.2
55
145
WX723
NOMESCO Finland
CPAP therapy
5.3
19.0
40
82
R01AD12
ATC
fluticasone furoate; nasal
2.6
18.5
168
877
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.9
18.0
59
172
N03AX12
ATC
[U] gabapentin; oral
3.5
17.9
71
235
A02BC02
ATC
pantoprazole; systemic
2.7
17.7
283
1919
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
17.3
161
846
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
17.1
129
612
M02AA07
ATC
piroxicam; topical
2.6
16.9
143
717
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.0
16.8
52
145
SPAT1260
SPAT
Consultation of another employee
3.0
16.8
87
338
M70.6
ICD-10 Finland
Trochanteric bursitis
3.8
16.6
56
166
N02BF01
ATC
gabapentin; oral
4.0
16.5
51
142
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
19.6
16.2
24
13
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
14.6
15.7
26
19
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.5
15.7
40
96
M54.5
ICD-10 Finland
Low back pain
2.4
15.6
161
877
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.9
15.6
50
143
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.1
15.5
72
262
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
15.4
186
1085
SPAT1312
SPAT
General health counselling
2.5
15.3
143
744
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
5.6
14.9
29
55
H02AB06
ATC
prednisolone; systemic
2.3
14.5
194
1174
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
28.4
14.4
19
7
M01AC06
ATC
meloxicam; systemic, rectal
2.4
14.4
150
816
M03BX02
ATC
tizanidine; oral
2.4
14.3
270
1886
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
6.3
14.0
24
40
SPAT1377
SPAT
Polysomnography
5.9
14.0
26
47
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.9
13.8
31
67
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.1
13.7
63
227
L08
ICPC
Shoulder symptom/complaint
2.6
13.7
96
434
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.1
13.5
39
103
M79.7
ICD-10 Finland
Fibromyalgia
19.1
13.5
20
11
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
13.4
154
867
L15
ICPC
Knee symptom/complaint
2.4
13.4
114
563
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
13.3
186
1134
M67.4
ICD-10 Finland
Ganglion
5.2
13.3
28
57
SPAT1211
SPAT
Application of soft bandage
3.7
13.0
43
125
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
12.1
13.0
23
20
M54.4
ICD-10 Finland
Lumbago with sciatica
2.7
12.9
81
345
A02BC01
ATC
omeprazole; systemic
2.4
12.8
114
573
Z01.9
ICD-10 Finland
Special examination, unspecified
3.9
12.8
39
107
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
12.6
43
128
M01AX17
ATC
nimesulide; oral
2.6
12.6
91
416
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.9
12.5
38
104
XX3DW
NOMESCO Finland
Time consuming IT work
3.1
12.5
59
215
M01AX05
ATC
glucosamine; oral
2.8
12.5
73
300
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
12.4
112
566
M54.1
ICD-10 Finland
Radiculopathy
5.5
12.2
24
46
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
12.1
86
389
WX780
NOMESCO Finland
Remote monitoring CPAP
4.1
11.9
34
89
N06AA09
ATC
amitriptyline; systemic
3.5
11.6
41
125
UDC00
NOMESCO Finland
Ear microscopy
3.7
11.6
39
115
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
11.4
158
947
L13
ICPC
Hip symptom/complaint
2.6
11.3
75
327
SPAT1301
SPAT
No procedures
2.2
11.2
124
679
J01FA09
ATC
clarithromycin; systemic
2.2
11.2
135
765
SPAT1263
SPAT
Sampling
2.1
11.2
170
1053
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.3
11.2
30
75
WX402
NOMESCO Finland
General anaesthesia
2.3
11.2
106
545
ZXC50
NOMESCO Finland
Cryotherapy
6.0
11.1
20
35
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.1
10.9
49
173
M09AX01
ATC
hyaluronic acid; parenteral
5.4
10.9
22
43
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
10.8
139
806
M01AE02
ATC
naproxen; oral, rectal
2.1
10.8
233
1634
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
10.5
97
492
M03BC51
ATC
orphenadrine, combinations; systemic
2.2
10.5
117
641
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
10.5
10
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.8
10.3
56
220
R51.80
ICD-10 Finland
Headache
2.5
10.3
71
315
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.7
10.3
59
239
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.3
10.1
27
67
M01AH02
ATC
rofecoxib; oral
3.0
10.1
46
164
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.7
10.0
33
96
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
9.9
105
561
NH3EA
NOMESCO Finland
Feet X-ray examination with load
11.0
9.9
18
17
J01FA10
ATC
azithromycin; systemic
2.0
9.9
243
1762
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.3
9.9
26
64
M79.1
ICD-10 Finland
Myalgia
2.6
9.8
61
257
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
9.8
39
128
R01AD08
ATC
fluticasone; nasal
2.1
9.8
128
742
G47.3
ICD-10 Finland
Sleep apnoea
2.2
9.8
104
557
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
9.7
82
399
G54.0
ICD-10 Finland
Brachial plexus disorders
7.5
9.6
22
31
SPAT1281
SPAT
Other administrative function
3.2
9.5
40
136
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.3
9.5
37
120
M02AA10
ATC
ketoprofen; topical
2.5
9.4
65
288
R52.2
ICD-10 Finland
Other chronic pain
4.7
9.4
22
49
R06AE07
ATC
cetirizine; oral
2.0
9.4
180
1191
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
11.1
9.4
17
16
WX110
NOMESCO Finland
Infiltration anesthesia
2.1
9.3
293
2296
A02BC05
ATC
esomeprazole; systemic
2.0
9.2
155
981
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
11.9
9.1
16
14
J01AA02
ATC
doxycycline; systemic
2.2
9.1
308
2466
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
9.1
223
1595
N02BE01
ATC
paracetamol; systemic, rectal
2.8
9.1
350
2962
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
9.1
110
617
L03
ICPC
Low back symptom/complaint
2.1
9.0
114
651
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.5
9.0
31
93
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
8.9
76
370
M77.1
ICD-10 Finland
Lateral epicondylitis
3.3
8.9
35
114
XF404
NOMESCO Finland
Ambulatory ECG
3.1
8.8
39
137
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
8.6
117
683
HAHOM, ,
NOMESCO Finland
9.3
8.6
17
19
H92.0
ICD-10 Finland
Otalgia
3.3
8.6
33
106
M54
ICD-10 Finland
Dorsalgia
2.5
8.6
59
261
SCA02
NOMESCO Finland
Preventive oral health care
2.6
8.6
54
229
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
8.4
27
77
ACC51
NOMESCO Finland
Release of median nerve
3.4
8.4
30
92
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
8.3
162
1068
X58
ICD-10 Finland
Exposure to other specified factors
2.3
8.2
65
306
D82
ICPC
Teeth/gum disease
1.9
8.2
166
1106
L90
ICPC
Osteoarthrosis of knee
3.3
8.2
32
104
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.3
8.1
31
99
A02BA02
ATC
ranitidine; systemic
2.3
8.1
69
335
M01AH01
ATC
celecoxib; oral
2.3
8.1
66
315
M01AB08
ATC
etodolac; oral
3.2
8.1
32
105
WX204
NOMESCO Finland
Axillary plexus blockaced
4.8
8.0
18
39
1223
FHL
Arthroscopy and articular cartilage surgery
13.4
7.9
13
10
R06.0
ICD-10 Finland
Dyspnoea
2.0
7.9
100
567
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
7.9
42
163
R53
ICD-10 Finland
Malaise and fatigue
2.0
7.9
99
560
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.8
7.8
41
158
UJF32
NOMESCO Finland
Coloscopy
2.0
7.7
93
518
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.8
7.7
24
67
XX9TE
NOMESCO Finland
Compementary ultrasound examination
18.8
7.6
11
6
TNX10, ,
SPAT
18.8
7.6
11
6
SPAT1097
SPAT
Recording of ECG
2.4
7.6
55
248
R03BA05
ATC
fluticasone; inhalant
2.2
7.6
75
387
B01AB05
ATC
enoxaparin; parenteral
1.9
7.5
113
679
M23
ICD-10 Finland
Internal derangement of knee
4.6
7.5
18
41
B01AB10
ATC
tinzaparin; parenteral
2.5
7.5
48
205
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
7.5
43
174
J01DB01
ATC
cefalexin; oral
2.1
7.4
322
2695
L86
ICPC
Back syndrome with radiating pain
3.3
7.4
28
89
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.8
7.4
39
151
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
7.4
55
252
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.3
7.4
19
46
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
7.3
48
207
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.5
7.3
18
29
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
+∞
7.3
7
*
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.8
7.3
22
60
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.4
7.3
18
42
D07AC01
ATC
betamethasone; topical
1.8
7.3
142
927
SPAT1310
SPAT
Counselling related to known health issue
1.9
7.3
118
727
R03AC02
ATC
salbutamol; inhalant
1.8
7.2
216
1600
R4110, ,
SPAT
2.3
7.2
57
268
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.4
7.2
52
235
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
7.1
93
532
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.5
7.0
17
39
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
7.0
151
1014
WZC00, ,
SPAT
2.2
7.0
63
313
L12
ICPC
Hand/finger symptom/complaint
2.1
6.9
69
357
L01
ICPC
Neck symptom/complaint
2.2
6.9
66
336
XA402
NOMESCO Finland
ENMG
8.5
6.9
14
17
N05BA01
ATC
diazepam; systemic, rectal
2.3
6.9
54
253
L04AB01
ATC
etanercept; parenteral
11.2
6.8
12
11
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
40.8
6.8
8
*
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
17.1
6.8
10
6
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
7.4
6.8
15
21
M54.2
ICD-10 Finland
Cervicalgia
2.7
6.7
37
146
N02BF02
ATC
pregabalin; oral
3.2
6.7
26
84
R03DC03
ATC
montelukast; oral
2.1
6.7
69
361
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
23.0
6.7
9
*
M48.0
ICD-10 Finland
Spinal stenosis
2.6
6.7
39
159
J01FA06
ATC
roxithromycin; oral
1.8
6.6
146
983
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
10.3
6.6
12
12
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.6
96
569
L01BA01
ATC
methotrexate; systemic
5.9
6.5
17
30
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.5
81
454
L09
ICPC
Arm symptom/complaint
3.2
6.5
26
86
L04AX03
ATC
methotrexate; systemic
2.6
6.4
39
162
K07.60
ICD-10 Finland
Snapping jaw
3.3
6.4
24
76
NF1AA
NOMESCO Finland
Hip X-ray examination
3.1
6.4
27
92
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.4
6.4
13
16
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.4
50
234
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
6.1
6.4
16
27
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
9.5
6.3
12
13
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.3
119
763
N02AA05
ATC
oxycodone; systemic
2.2
6.3
55
269
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.2
6.3
25
82
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
+∞
6.3
6
*
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
27.1
6.2
8
*
SCA03
NOMESCO Finland
Preventive oral health care, extensive
3.1
6.2
26
88
ZXD00
NOMESCO Finland
Emergency procedure
4.1
6.2
17
43
N03AE01
ATC
clonazepam; systemic
3.2
6.2
25
83
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.9
6.2
18
48
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.1
155
1080
N05CF01
ATC
zopiclone; oral
1.8
6.1
113
719
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.7
6.1
33
129
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
8.8
6.1
12
14
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
10.2
6.1
11
11
TQW40, ,
SPAT
2.4
6.1
44
199
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
6.1
16
29
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
6.0
33
130
M01AH03
ATC
valdecoxib; oral
3.2
6.0
24
79
N05BA04
ATC
oxazepam; oral
1.8
6.0
100
616
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
125
282
6.06
55.92
3.6
2.9
—
—
—
0
0
97
222
5.49
41.79
4.4
3.6
1.22
1.23
mmol/l
0.32
84
197
199
865
3.66
35.24
4.1
3.3
0.00
0.01
estimate
0.74
120
312
269
1492
3.60
30.97
17.2
10.2
0.00
0.00
e9/l
0.80
255
1221
35
38
10.02
29.59
2.0
1.8
1.55
1.61
mmol/l
0.17
35
38
205
1077
2.91
23.75
4.9
3.1
16.21
28.21
ng/l
2.72
130
686
192
981
2.89
23.33
3.6
2.6
0.02
0.02
estimate
0.03
116
267
223
1295
2.69
20.23
4.0
3.0
0.01
0.03
estimate
0.66
116
280
34
62
5.91
18.23
1.6
1.7
—
—
—
0
0
213
1288
2.44
16.62
17.2
10.2
1.14
1.18
inr
0.63
198
1061
112
514
2.66
15.67
1.3
1.2
1.28
14.84
u/ml
2.64
53
198
126
619
2.53
15.27
2.9
2.3
5.44
6.67
e6/l
0.33
113
562
122
602
2.50
14.55
2.1
1.7
207292080.19
29735262.39
pmol/l
0.60
96
528
248
1665
2.35
14.45
4.0
3.2
0.00
0.00
estimate
0.50
122
326
117
568
2.52
14.43
1.3
1.3
23.89
33.42
iu/ml
0.60
31
161
249
1679
2.34
14.30
4.0
3.2
0.00
0.00
estimate
-0.00
126
333
314
2355
2.73
14.13
6.1
3.7
10.98
10.43
mm/h
0.29
289
2203
249
1697
2.30
13.68
4.0
3.2
0.00
0.00
estimate
-0.00
121
312
174
1042
2.21
12.94
2.8
3.7
2.36
2.35
mmol/l
0.15
165
972
148
837
2.24
12.61
2.5
2.1
111.89
204.52
u/l
3.14
133
792
122
682
2.15
10.36
2.2
1.7
0.59
1.19
mg/l
4.81
98
523
236
2929
0.51
9.27
20.1
16.4
331.84
333.08
g/l
1.39
236
2911
307
2452
2.20
9.21
10.8
7.7
76.29
77.29
u/l
0.18
291
2333
19
39
5.07
8.93
2.0
1.6
—
—
—
0
0
16
16
10.37
8.60
1.8
1.4
—
—
—
0
0
16
16
10.37
8.60
1.9
1.5
—
—
—
0
0
133
813
1.97
8.59
3.0
2.7
0.89
0.40
e6/l
0.28
103
574
247
1861
1.90
8.27
9.7
10.3
4.17
4.05
e9/l
0.30
228
1627
16
18
9.22
8.11
1.8
1.4
—
—
—
0
0
17
23
7.68
7.75
2.0
1.4
—
—
—
0
0
184
1293
1.80
7.44
5.5
5.2
35.86
36.45
g/l
0.73
166
1237
19
46
4.29
7.36
1.8
1.4
—
—
—
0
0
154
1037
1.80
7.09
3.3
2.8
—
—
—
0
0
141
926
1.82
7.05
3.1
2.5
52.71
70.50
u/l
1.79
125
875
198
1438
1.77
7.02
2.8
2.7
—
—
estimate
—
0
0
19
48
4.11
6.97
2.0
2.0
—
—
—
0
0
22
62
3.70
6.97
4.2
3.1
8.94
8.38
pmol/l
0.08
22
62
22
63
3.64
6.82
1.4
1.3
—
—
—
0
0
335
2881
2.17
6.67
21.9
16.1
13.45
13.46
%
0.06
330
2848
312
2617
1.97
6.64
5.6
4.2
14.92
14.61
pmol/l
1.31
283
2421
17
41
4.29
6.61
2.1
1.5
—
—
—
0
0
95
560
1.92
6.61
3.0
3.0
2.45
2.44
mmol/l
0.26
85
513
20
59
3.52
5.94
1.9
1.4
—
—
—
0
0
17
34
5.18
5.94
1.8
2.1
31.71
34.29
pg
1.49
17
34
14
22
6.56
5.91
1.4
1.0
8.88
0.69
u/ml
—
7
10
360
3227
2.55
5.85
18.8
11.8
85.86
85.51
ml/min/173m2
0.13
338
2935
20
60
3.46
5.80
1.8
1.4
—
—
—
0
0
70
396
1.94
5.44
2.4
1.7
1497.55
1199.99
nmol/l
1.96
51
304
362
3285
2.47
5.15
21.3
12.4
15.99
23.44
mg/l
5.46
321
2613
49
251
2.09
5.01
1.1
1.3
81.25
148.78
u/ml
1.06
14
108
15
33
4.68
4.92
1.0
1.1
—
—
—
0
0
20
69
3.00
4.67
1.9
1.4
—
—
—
0
0
24
93
2.68
4.56
1.7
1.3
1.12
1.27
g/l
1.43
24
85
22
82
2.78
4.50
2.0
1.7
—
—
—
0
0
22
82
2.78
4.50
2.0
1.6
—
—
—
0
0
109
751
1.63
4.24
2.5
2.0
3.16
2.74
mg/l
1.07
86
653
23
91
2.62
4.21
1.7
1.4
0.21
0.25
g/l
1.69
23
84
169
1292
1.54
4.20
8.0
6.8
1.21
1.21
mmol/l
0.18
156
1213
113
795
1.59
4.01
2.4
2.6
331.70
340.21
umol/l
0.39
93
716
204
1645
1.50
3.84
3.9
2.8
114.12
111.11
ug/l
0.09
180
1548
185
1467
1.50
3.75
7.3
7.4
1.22
1.21
mmol/l
0.31
117
1290
362
3355
2.14
3.69
20.5
14.4
139.57
139.75
mmol/l
0.61
357
3286
71
456
1.68
3.59
2.2
1.8
—
—
—
0
0
362
3363
2.10
3.53
20.8
14.5
3.98
3.95
mmol/l
1.63
357
3284
341
3109
1.78
3.52
6.3
5.0
1.70
1.86
mu/l
2.03
314
2896
198
1614
1.46
3.38
8.7
6.7
9.43
11.10
umol/l
3.08
180
1545
106
772
1.51
3.14
1.5
1.3
0.60
1.71
u/ml
1.35
51
226
375
3562
2.47
2.94
15.0
10.5
26.45
27.07
u/l
0.36
367
3474
274
2415
1.46
2.86
4.4
3.2
45.02
44.66
u/l
0.03
252
2311
66
441
1.60
2.85
3.6
2.3
2.38
2.34
g/l
0.29
57
411
49
303
1.71
2.85
2.8
2.2
13.98
13.76
nmol/l
0.08
42
287
17
362
0.45
2.82
4.1
4.4
33.92
31.58
%
0.50
12
248
18
79
2.34
2.72
3.6
4.3
15.46
58.64
mg/l
—
8
68
10
29
3.51
2.71
1.9
1.3
258.20
167.82
pmol/l
—
10
29
19
86
2.27
2.68
1.7
2.3
—
—
—
0
0
10
30
3.39
2.62
1.1
1.1
—
—
—
0
0
28
150
1.93
2.59
1.5
1.5
392.00
305.79
mu/l
0.53
22
137
50
321
1.64
2.54
2.1
1.7
—
—
—
0
0
10
31
3.28
2.53
1.1
1.3
—
—
—
0
0
21
103
2.10
2.46
2.0
1.5
—
0.01
—
0
16
16
70
2.34
2.44
1.3
1.4
379.90
223.52
u/ml
—
10
40
25
132
1.96
2.42
2.4
1.6
6.37
5.61
iu/ml
—
7
26
17
77
2.26
2.41
1.5
1.8
—
—
—
0
0
336
3123
1.56
2.35
6.0
5.5
38.31
38.60
mmol/mol
0.30
300
2959
67
471
1.51
2.32
3.6
2.3
14.73
14.02
umol/l
0.28
58
445
51
337
1.59
2.32
2.0
1.6
—
—
—
0
0
172
1433
1.36
2.31
2.1
1.9
1.47
1.36
mmol/l
0.71
115
1233
17
79
2.20
2.28
3.7
4.3
31.36
54.82
mg/l
—
7
68
23
121
1.96
2.26
1.9
2.0
172.02
2099.13
u/l
—
10
53
15
67
2.29
2.20
3.5
4.3
7.07
2.69
ratio
—
5
37
253
2246
1.36
2.20
3.1
3.2
—
—
—
0
0
14
61
2.34
2.17
1.6
1.3
3575.22
9067.30
e6/l
—
9
47
27
153
1.82
2.14
3.7
3.5
2.54
1.89
mmol/l
0.54
17
114
97
745
1.40
2.12
4.5
3.3
847.61
1083.39
ng/l
0.32
75
620
14
63
2.27
2.03
2.0
1.9
169.73
113.44
ug/min
—
9
35
14
65
2.20
1.90
1.2
1.6
85.36
50.08
ug/l
0.98
14
65
56
396
1.48
1.90
4.0
2.3
24.90
24.42
%
0.09
47
375
89
686
1.39
1.90
1.8
1.5
—
—
—
0
0
7
22
3.22
1.89
1.1
1.0
—
—
—
0
0
7
22
3.22
1.89
1.3
1.3
70.14
79.27
umol/l
—
7
22
18
93
1.98
1.88
1.3
1.4
209.59
308.80
ug/g
—
8
54
8
28
2.89
1.87
1.1
1.1
—
—
—
0
0
168
1429
1.31
1.85
3.0
2.4
78.99
74.89
nmol/l
1.13
156
1316
8
29
2.79
1.80
1.1
1.1
—
—
—
0
0
103
820
1.35
1.79
1.6
1.6
18.52
20.43
nmol/l
0.56
86
707
9
36
2.53
1.75
1.1
1.1
—
—
—
0
0
6
19
3.19
1.66
1.7
1.8
—
—
—
0
0
380
3703
2.13
1.66
29.4
19.6
4.53
4.55
e12/l
0.57
374
3623
380
3700
2.17
1.66
29.5
19.7
255.77
253.31
e9/l
0.33
375
3629
128
1067
1.30
1.60
3.3
3.3
8.60
8.13
mmol/l
0.40
90
918
7
26
2.72
1.58
1.0
1.2
125.57
105.04
pmol/l
—
7
26
32
473
0.65
1.57
1.9
2.0
3.45
3.52
ratio
0.15
26
381
5
15
3.36
1.53
4.4
4.6
—
—
—
0
0
7
27
2.62
1.52
1.0
1.1
—
—
—
0
0
36
244
1.52
1.51
1.9
2.6
70.68
67.62
ml/min/173m2
0.17
19
98
13
65
2.03
1.50
1.6
1.5
—
—
—
0
0
11
52
2.15
1.45
1.3
1.1
—
—
—
0
0
5
16
3.15
1.44
1.2
1.1
1703.40
1505.06
miu/ml
—
5
16
32
214
1.54
1.43
1.3
1.4
23.34
25.41
iu/l
0.14
25
197
10
46
2.20
1.41
1.9
1.5
—
—
—
0
0
6
23
2.63
1.37
2.0
1.7
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
17
2.97
1.36
1.6
2.2
152.20
129.59
%
—
5
17
56
726
0.73
1.35
2.6
2.3
—
—
—
0
0
42
565
0.71
1.27
3.8
3.4
312.10
375.29
ng/l
0.08
30
419
6
25
2.42
1.25
1.0
1.1
—
—
—
0
0
12
63
1.93
1.24
1.3
1.2
—
0.97
—
0
6
16
94
1.73
1.19
1.3
1.7
—
—
—
0
0
337
3226
1.33
1.14
4.7
4.5
5.88
5.84
mmol/l
0.24
308
3005
11
58
1.92
1.13
6.3
4.9
126.91
164.07
u/ml
0.13
11
52
27
186
1.49
1.09
1.8
1.7
—
—
—
0
0
5
21
2.40
1.09
1.0
1.1
—
—
—
0
0
5
21
2.40
1.09
1.6
5.0
239.27
1283.90
mg
—
5
21
12
67
1.82
1.06
1.3
1.3
—
—
—
0
0
115
991
1.23
1.05
5.2
4.1
10.41
9.07
mg/mmol
0.08
62
630
5
22
2.29
1.03
1.0
1.1
—
—
—
0
0
5
22
2.29
1.03
1.0
1.1
—
—
—
0
0
132
1161
1.21
0.97
5.2
3.4
32.32
32.10
u/l
0.02
122
1119
24
338
0.69
0.97
1.6
1.8
3.36
3.46
mmol/l
0.31
17
254
36
468
0.75
0.91
2.8
2.7
3.33
2.81
e6/l
0.12
16
222
19
127
1.52
0.90
1.7
1.8
—
—
—
0
0
12
73
1.66
0.82
2.8
4.2
1.23
1.29
mmol/l
0.09
12
73
27
199
1.38
0.80
1.5
1.7
1146.77
994.80
mu/l
0.23
20
169
0
24
0.00
0.79
0.0
10.2
—
50.11
—
0
9
11
67
1.66
0.76
3.0
3.4
3.68
3.85
mmol/l
0.61
11
67
9
54
1.68
0.75
1.2
1.1
—
—
—
0
0
9
55
1.65
0.74
1.3
1.7
—
—
—
0
0
56
465
1.24
0.73
2.0
1.9
1.40
1.39
%
0.05
47
415
6
110
0.54
0.73
1.2
1.4
—
—
—
0
0
12
77
1.58
0.69
1.1
1.4
—
—
—
0
0
68
785
0.84
0.64
3.8
4.1
17.17
21.42
%
1.90
32
326
24
182
1.34
0.63
1.1
1.0
—
—
—
0
0
14
96
1.48
0.62
1.3
1.3
—
—
—
0
0
332
3224
1.20
0.61
4.1
4.0
1.41
1.30
mmol/l
1.50
300
3041
8
51
1.58
0.60
1.1
1.2
171.13
320.78
pmol/l
—
8
46
42
346
1.24
0.60
3.8
2.6
5.52
6.35
umol/l
0.32
30
306
7
111
0.62
0.59
2.4
2.0
—
—
—
0
0
10
149
0.66
0.57
1.0
1.6
—
—
—
0
0
105
947
1.15
0.56
5.2
4.7
2.07
2.31
ug/l
0.15
89
870
11
159
0.68
0.55
9.9
14.1
15.85
15.97
%
0.04
11
152
20
151
1.34
0.55
1.4
1.6
—
—
—
0
0
21
269
0.77
0.52
1.9
2.0
—
—
—
0
0
50
428
1.19
0.51
2.2
2.0
—
—
—
0
0
11
75
1.48
0.51
2.0
1.2
—
—
—
0
0
5
32
1.57
0.42
2.8
4.4
23.20
58.04
u/ml
—
5
32
14
105
1.35
0.41
1.9
1.9
13.64
5.13
iu/l
—
7
47
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
64
714
0.88
0.41
4.7
3.1
1.02
1.02
kg/l
0.03
45
473
0
17
0.00
0.40
0.0
1.2
—
168.44
—
0
17
7
104
0.67
0.40
2.0
1.8
—
—
—
0
0
16
125
1.29
0.37
1.7
1.6
—
—
—
0
0
6
42
1.44
0.35
1.0
1.4
—
—
—
0
0
18
222
0.80
0.35
1.8
2.0
—
—
—
0
0
45
508
0.87
0.35
2.2
2.5
1.82
0.98
e6/l
0.54
23
263
53
475
1.13
0.33
2.2
2.1
—
—
—
0
0
21
175
1.21
0.31
2.3
1.5
0.43
0.26
mg/l
0.33
11
84
7
54
1.30
0.30
1.1
1.7
—
—
—
0
0
13
162
0.80
0.29
1.0
1.1
1.43
1.54
g/l
0.58
13
162
19
159
1.20
0.27
6.3
10.3
26.45
24.41
mmol/l
1.88
19
151
16
132
1.22
0.26
1.6
1.3
—
—
—
0
0
5
75
0.66
0.26
1.2
1.9
0.81
0.90
nmol/l
—
5
62
35
314
1.13
0.23
9.1
5.7
—
—
—
0
0
25
219
1.15
0.23
2.8
3.9
79.26
76.12
ng/l
0.10
19
202
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.64
—
0
14
14
165
0.84
0.20
1.4
1.2
1.08
0.92
g/l
0.58
14
165
6
50
1.20
0.20
2.5
1.5
—
—
—
0
0
65
612
1.07
0.18
1.7
1.6
—
—
—
0
0
12
138
0.87
0.13
1.2
1.5
—
—
—
0
0
17
152
1.12
0.12
1.1
1.3
—
—
—
0
0
131
1275
1.04
0.12
1.9
1.9
94.74
95.04
pmol/l
0.03
80
694
57
597
0.95
0.11
3.1
2.9
0.59
0.74
ug/l
1.41
35
343
340
3424
0.94
0.11
5.7
5.3
2.82
2.81
mmol/l
0.08
309
3246
5
45
1.11
0.10
1.2
1.2
—
—
—
0
0
341
3389
1.05
0.08
5.3
4.7
4.76
4.73
mmol/l
0.18
310
3224
17
156
1.09
0.08
5.0
2.5
0.50
0.60
%
0.80
17
156
13
143
0.91
0.07
1.1
1.4
197.57
247.73
miu/ml
—
6
68
28
265
1.06
0.07
7.6
10.9
123.18
122.12
g/l
0.10
28
259
339
3374
1.04
0.06
5.2
4.7
1.46
1.46
mmol/l
0.08
306
3190
17
159
1.07
0.05
5.0
2.5
1.08
1.18
%
0.35
17
159
24
251
0.95
0.04
1.5
1.4
—
—
—
0
0
17
172
0.99
0.00
9.2
9.9
0.73
0.64
%
0.47
17
172
17
169
1.01
0.00
9.4
10.2
93.82
93.39
%
0.15
17
169
38
379
1.00
0.00
7.3
6.8
104.61
104.59
mmol/l
0.01
38
379
17
175
0.97
0.00
9.4
9.6
1.43
1.42
%
0.02
17
175
12
116
1.04
0.00
1.5
1.5
2.42
1.14
ratio
—
6
79
12
116
1.04
0.00
1.5
1.5
—
—
—
0
0
12
116
1.04
0.00
1.5
1.5
1.01
1.08
ratio
—
6
79
12
116
1.04
0.00
1.5
1.5
0.99
0.98
ratio
—
6
79
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
7
70
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
10.71
—
0
9
0
5
0.00
-0.00
0.0
8.2
—
10.62
—
0
5
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.60
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
3.0
1.7
12.60
12.98
%
—
5
50
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
78
0.90
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
57.06
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_FATPADHYPERTROPHY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FATPADHYPERTROPHY | 1.243 [0.99, 1.57] | 0.065 |
| Birth year | 0.993 [0.98, 1.0] | 0.123 |
During the follow-up period (1.1.1998 — 31.12.2019), 97 out of 968 females with M13_FATPADHYPERTROPHY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FATPADHYPERTROPHY | 1.002 [0.78, 1.29] | 0.987 |
| Birth year | 0.99 [0.98, 1.0] | 0.092 |
During the follow-up period (1.1.1998 — 31.12.2019), 68 out of 711 males with M13_FATPADHYPERTROPHY died.
Mortality risk
Mortality risk for people of age
years, who have M13_FATPADHYPERTROPHY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | 0.239% |
| 5 | 0.548% | 1.293% |
| 10 | 1.615% | 3.128% |
| 15 | 3.274% | 6.069% |
| 20 | 5.57% | 10.718% |
Relationships between endpoints
↥Index endpoint: M13_FATPADHYPERTROPHY – Hypertrophy of (infrapatellar) fat pad
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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