No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
527 |
4. Check minimum number of eventsNone |
527 |
5. Include endpointsNone |
527 |
6. Filter based on genotype QC (FinnGen only) |
456 |
Control definitions (FinnGen only)
- Control exclude
- D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D69
- Name in latin
- Thrombocytopenia secundaria
Similar endpoints
↥List of similar endpoints to
Secondary thrombocytopenia
based on the number of shared cases.
Similar with more cases:
- Purpura and other haemorrhagic conditions
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3098 | 1537 | 1524 |
| Only index persons | 2347 | 1177 | 1170 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 61.19 | 61.53 | 60.87 |
| Only index persons | 60.76 | 60.97 | 60.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 456 | 236 | 220 |
| Unadjusted period prevalence (%) | 0.09 | 0.08 | 0.10 |
| Median age at first event (years) | 62.32 | 60.95 | 63.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 471
- Matched controls
- 4710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.5
ICD-10 Finland
Secondary thrombocytopenia
+∞
307.7
442
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
78.5
254.4
139
25
WW500
NOMESCO Finland
Blood transfusion
32.9
242.4
172
81
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
17.8
159.9
148
118
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.6
124.2
120
101
XW000
NOMESCO Finland
Bone marrow biopsy
17.5
116.2
103
74
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
15.8
114.3
108
87
L03AA13
ATC
pegfilgrastim; parenteral
13.3
103.6
109
104
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.4
102.9
173
303
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
168.3
102.9
105
8
H02AB02
ATC
dexamethasone; systemic
7.9
97.6
177
335
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
17.3
92.6
81
56
L03AA02
ATC
filgrastim; parenteral
16.1
88.2
80
59
A04AA01
ATC
ondansetron; systemic, rectal
8.5
85.3
131
204
Z51.5
ICD-10 Finland
Palliative care
8.0
83.7
137
229
ZX120
NOMESCO Finland
Intravenous
7.5
79.2
138
246
L03AA14
ATC
lipegfilgrastim; parenteral
19.1
75.9
62
37
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
23.8
74.6
55
26
N02AA05
ATC
oxycodone; systemic
5.4
69.2
199
561
A03FA01
ATC
metoclopramide; systemic, rectal
5.2
69.0
224
698
JN4BD
NOMESCO Finland
Extensive body CT
6.4
67.5
140
294
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.5
67.1
98
142
JN4AD
NOMESCO Finland
Body CT examination
5.9
65.9
150
343
JN6AD
NOMESCO Finland
CT of torso and neck
18.3
61.6
51
31
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
57.7
172
490
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
19.0
55.6
45
26
B03XA02
ATC
darbepoetin alfa; parenteral
16.0
55.3
49
34
R50.9
ICD-10 Finland
Fever, unspecified
4.9
54.3
156
429
A04AA02
ATC
granisetron; systemic, transdermal
6.4
49.3
93
175
D70.89
ICD-10 Finland
Neutropenic splenomegaly
22.2
49.2
37
18
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.6
49.0
53
51
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
45.6
43
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.7
43.1
53
61
M04AA01
ATC
allopurinol; systemic
4.5
41.8
127
358
D64.9
ICD-10 Finland
Anaemia, unspecified
4.7
40.9
112
291
130
Kela drug reimbursment
Malignant tumour
4.6
34.5
94
241
128
Kela drug reimbursment
Cancers of female genital organs
11.4
34.4
37
35
A41.9
ICD-10 Finland
Sepsis, unspecified
7.6
34.2
51
74
WF049
NOMESCO Finland
Radiotherapy of metastasis
7.6
34.2
51
74
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.5
32.5
68
139
WZC00
NOMESCO Finland
Treatment plan or consultation
3.1
31.5
246
1238
B01AB10
ATC
tinzaparin; parenteral
4.0
30.2
102
306
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
30.1
303
1741
WW300
NOMESCO Finland
Transfer of autologic stem cells
110.4
29.0
31
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
28.9
112
368
ZX112
NOMESCO Finland
Subcutaneous
8.6
28.1
37
46
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.7
26.4
96
301
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.3
25.4
45
78
TK800
NOMESCO Finland
Hemodialysis
9.4
25.3
31
35
H02AB06
ATC
prednisolone; systemic
2.8
25.0
286
1694
A04AA55
ATC
palonosetron, combinations; systemic
5.8
24.7
48
91
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
9.4
24.4
30
34
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
31.1
24.4
32
11
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
9.3
23.5
29
33
J01MA12
ATC
levofloxacin; systemic
3.0
22.9
132
546
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.1
22.8
41
72
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.2
22.1
64
170
TGC00
NOMESCO Finland
Bronchial lavation
6.4
22.0
38
64
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
21.9
209
1113
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.3
21.6
46
95
L04AA06
ATC
mycophenolic acid; systemic
8.3
21.5
29
37
C03CA01
ATC
furosemide; systemic
2.6
21.4
184
930
WF004
NOMESCO Finland
Palliative radiotherapy
8.9
21.2
27
32
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.6
20.8
52
123
ZX108
NOMESCO Finland
Inhalation
26.9
20.7
28
11
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.3
20.6
43
87
N03AX14
ATC
levetiracetam; systemic
6.9
20.3
32
49
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
20.1
148
690
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
16.3
20.0
32
21
28711
ICD-8 Finland
Purpura and other haemorrhagic conditions, Thrombocytopenia symptomatica
+∞
19.9
19
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
19.9
19
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
15.5
19.7
32
22
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.3
19.3
26
33
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
8.3
19.3
26
33
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
19.2
163
811
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
18.7
81
281
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
18.1
75
253
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.2
18.1
39
81
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
7.6
18.0
26
36
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
21.1
17.9
26
13
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
7.7
17.5
25
34
XX3DW
NOMESCO Finland
Time consuming IT work
3.0
17.5
87
327
B01AB05
ATC
enoxaparin; parenteral
2.4
17.4
184
1003
R18
ICD-10 Finland
Ascites
7.2
17.1
26
38
212
Kela drug reimbursment
Gout
7.8
17.1
24
32
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
16.9
95
382
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.5
16.8
63
199
C83.1
ICD-10 Finland
Mantle cell lymphoma
31.3
16.2
21
7
A02BC02
ATC
pantoprazole; systemic
2.5
15.8
360
2670
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
15.3
70
250
H02AB09
ATC
hydrocortisone; systemic
6.3
15.3
26
43
GD1AD
NOMESCO Finland
Thorax CT examination
3.5
15.0
55
171
A06AD11
ATC
lactulose; oral
2.7
15.0
94
399
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
17.2
14.9
23
14
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
26.0
14.8
20
8
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.2
14.5
25
42
L01AX03
ATC
temozolomide; systemic
17.7
14.4
22
13
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
4.5
14.3
36
85
J01MA14
ATC
moxifloxacin; systemic
3.1
14.3
66
237
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
12.5
14.2
25
21
JAL30
NOMESCO Finland
Omentectomy
14.2
13.9
23
17
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
13.8
165
931
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.7
13.7
26
48
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.9
13.7
71
272
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
13.5
45
131
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
10.1
13.4
26
27
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
15.6
13.2
21
14
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.1
13.2
23
39
JN4CD
NOMESCO Finland
Very extensive body CT
4.5
12.9
32
75
C56
ICD-10 Finland
Malignant neoplasm of ovary
25.1
12.5
17
7
WW409
NOMESCO Finland
Other aferesis
25.1
12.5
17
7
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
20.7
12.5
18
9
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
20.7
12.5
18
9
C56.00
ICD-10 Finland
Malignant tumor of the ovary without histology
20.7
12.5
18
9
WF002
NOMESCO Finland
Radical radiotherapy
3.5
12.5
45
138
N18.8
ICD-10 Finland
Other chronic renal failure
6.2
12.2
21
35
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
10.5
12.1
23
23
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.6
12.1
29
66
L04AX01
ATC
azathioprine; systemic
4.3
12.0
32
79
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
11.8
75
319
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
30.9
11.7
15
5
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
11.7
61
234
B01AX05
ATC
fondaparinux; parenteral
19.5
11.7
17
9
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.5
11.6
29
68
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
23.6
11.6
16
7
ZXD05
NOMESCO Finland
Urgent procedure
2.1
11.6
161
950
WZC30
NOMESCO Finland
Teaching
2.3
11.5
104
518
D64.8
ICD-10 Finland
Other specified anaemias
8.7
11.4
24
29
127
Kela drug reimbursment
Transplant complication
9.2
11.4
23
26
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.9
11.3
25
53
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.4
11.2
22
42
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
11.1
102
512
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
11.1
39
118
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.8
10.8
20
36
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.0
10.6
23
48
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
12.4
10.4
18
15
M05BX04
ATC
denosumab; parenteral
3.2
10.2
42
140
J01MA02
ATC
ciprofloxacin; systemic
1.9
10.2
198
1301
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
10.1
79
368
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
4.8
10.1
23
50
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.4
10.0
25
59
ZXE00
NOMESCO Finland
One hour or less
1.9
9.9
193
1265
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
9.9
140
825
A41.8
ICD-10 Finland
Other specified sepsis
5.1
9.9
21
43
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.0
9.9
18
17
8461/3-C56.9
ICD-O-3
High grade serous carcinoma of ovary
26.7
9.9
13
5
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
9.8
9.8
19
20
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
9.7
47
173
AA1AD
NOMESCO Finland
CT of head and brain
1.9
9.7
154
944
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
9.7
135
791
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
9.6
34
103
2874X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Secondary thrombocytopenia[THROMBOCYTOPENIA SECUNDARIA NUD]
+∞
9.4
9
*
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
9.4
9
*
L04AD02
ATC
tacrolimus; systemic
11.0
9.4
17
16
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
9.3
74
347
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.3
54
219
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
16.0
9.1
14
9
1XC02, ,
NOMESCO Finland
16.0
9.1
14
9
JAH01
NOMESCO Finland
Laparoscopy
3.5
9.1
32
97
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
24.5
8.9
12
5
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
8.9
40
141
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
8.6
42
155
C57.0
ICD-10 Finland
Malignant neoplasm: Fallopian tube
28.1
8.5
11
*
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
91.6
8.4
9
*
A10AB05
ATC
insulin aspart; parenteral
2.6
8.4
50
205
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
8.4
8
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
9.7
8.3
16
17
E0000UV, ,
ATC
1.8
8.3
201
1391
ZX090
NOMESCO Finland
Other technic of radiotherapy
3.8
8.3
25
68
WX892
NOMESCO Finland
Monitored bed care
2.6
8.3
48
194
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
12.0
8.1
14
12
ED1AA
NOMESCO Finland
Mandibular X-ray examination
12.0
8.1
14
12
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
6.5
8.1
20
32
D68.8
ICD-10 Finland
Other specified coagulation defects
22.5
8.0
11
5
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
22.5
8.0
11
5
UJF32
NOMESCO Finland
Coloscopy
1.9
8.0
136
843
A11CC03
ATC
alfacalcidol; systemic
4.6
8.0
19
43
A04AD12
ATC
aprepitant; systemic
4.6
8.0
19
43
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.5
7.9
27
80
J05AB11
ATC
valaciclovir; oral
2.1
7.9
84
443
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.7
7.9
16
19
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
7.8
46
187
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
7.8
202
1417
TAB00
NOMESCO Finland
Lumbar puncture
3.1
7.8
32
107
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.5
7.7
19
44
A12AA04
ATC
calcium carbonate; oral
7.6
7.7
17
23
C57.9
ICD-10 Finland
Malignant neoplasm: Female genital organ, unspecified
45.7
7.7
9
*
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
4.6
7.7
18
40
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
18.7
7.6
11
6
LAF16
NOMESCO Finland
Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer
12.1
7.6
13
11
A06AH03
ATC
naloxegol; oral
7.3
7.5
17
24
C10AC01
ATC
colestyramine; oral
4.0
7.5
21
54
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
7.5
69
344
SPAT1255
SPAT
Intravenous administration of medicine
2.9
7.5
36
132
N17.8
ICD-10 Finland
Other acute renal failure
7.8
7.4
16
21
8461/3-C57.0
ICD-O-3
High grade serous carcinoma of fallopian tube
81.3
7.4
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
7.4
49
211
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
13.6
7.4
12
9
9680/3-C71.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of brain, NOS
+∞
7.3
7
*
3009
Kela drug reimbursment
Niraparib
+∞
7.3
7
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
7.5
7.2
16
22
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
7.5
7.2
16
22
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.6
7.2
17
38
ZZA00
NOMESCO Finland
Split skin graft
4.1
7.2
20
51
JAH00
NOMESCO Finland
Laparotomy
3.6
7.2
24
70
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.6
7.2
24
70
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.7
7.2
17
26
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
20.4
7.2
10
5
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
7.1
19
34
B01AA03
ATC
warfarin; systemic
2.0
7.1
88
489
ZXC40
NOMESCO Finland
Use of ultrasound
12.3
7.1
12
10
LCD00
NOMESCO Finland
Hysterectomy
3.3
7.1
27
86
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
10.2
7.1
13
13
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
7.0
81
439
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
7.0
62
304
H02AB07
ATC
prednisone; oral
2.1
6.9
70
361
N05BA06
ATC
lorazepam; systemic, sublingual
2.7
6.9
38
150
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
8.4
6.9
14
17
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
11.2
6.8
12
11
C10AA07
ATC
rosuvastatin; oral
0.5
6.8
72
1246
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.8
213
1558
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
6.8
22
63
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
2.7
6.8
37
145
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
6.8
50
227
N05CF01
ATC
zopiclone; oral
1.7
6.7
161
1097
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.1
6.7
28
95
L02BA03
ATC
fulvestrant; parenteral
12.5
6.6
11
9
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
12.5
6.6
11
9
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.3
6.6
17
41
R11
ICD-10 Finland
Nausea and vomiting
2.3
6.6
51
236
TJA10
NOMESCO Finland
Laparocentesis
70.8
6.4
7
*
WX872
NOMESCO Finland
Intensive care
2.8
6.4
31
114
A07AA02
ATC
nystatin; oral
2.7
6.4
35
138
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
9.4
6.3
12
13
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.4
6.3
12
13
TPX15
NOMESCO Finland
Removal of vascular injection port
18.3
6.3
9
5
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
+∞
6.3
6
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
6.3
6
*
L01XK02
ATC
niraparib; oral
+∞
6.3
6
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
+∞
6.3
6
*
28719
ICD-8 Finland
Purpura and other haemorrhagic conditions, Thrombocytopenia NUD
+∞
6.3
6
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
1510
Kela drug reimbursment
Niraparib
+∞
6.3
6
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
27.1
6.2
8
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
27.1
6.2
8
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
27.1
6.2
8
*
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
3.6
6.2
20
57
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.1
6.2
17
43
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.4
6.2
15
24
D07AB08
ATC
desonide; topical
2.1
6.2
57
284
WW200
NOMESCO Finland
Immunization
3.9
6.1
18
48
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.2
6.1
16
39
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.2
6.1
16
39
A46
ICD-10 Finland
Erysipelas
2.0
6.1
75
415
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
12.7
6.1
10
8
153
Kela drug reimbursment
Lenalidomid
12.7
6.1
10
8
L04AX04
ATC
lenalidomide; oral
12.7
6.1
10
8
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
8.8
6.1
12
14
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.2
6.1
11
11
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
10.2
6.1
11
11
A79
ICPC
Malignancy NOS
5.7
6.0
16
29
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.2
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
100
92
13.53
97.08
7.4
4.9
186.62
119.78
iu/ml
—
13
9
123
177
9.05
85.70
3.0
1.9
8.50
3.19
ug/l
0.54
118
161
169
374
6.49
78.09
6.1
2.6
80.15
70.00
e9/l
1.81
131
279
79
70
13.36
77.98
4.1
2.7
5741.56
606.17
u/ml
—
9
6
109
168
8.14
70.92
2.2
1.7
1.51
1.52
g/l
0.04
95
152
53
26
22.84
70.72
6.2
3.2
2.20
0.81
%
3.86
53
26
79
96
9.69
62.20
1.5
1.6
—
—
—
0
0
45
22
22.51
59.93
2.6
2.5
—
—
—
0
0
80
105
8.97
59.18
2.3
1.6
—
—
—
0
0
66
69
10.96
57.92
2.5
1.8
—
—
—
0
0
131
297
5.72
57.44
2.8
1.6
—
—
—
0
0
143
355
5.35
56.48
5.9
2.4
9.56
10.83
g/l
2.07
137
328
79
110
8.43
55.55
2.4
1.6
—
—
—
0
0
75
100
8.73
54.64
2.0
1.4
—
—
—
0
0
47
31
16.73
54.41
7.7
2.5
30.16
41.68
%
2.00
38
17
68
84
9.29
52.61
1.7
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
74
113
7.58
47.80
7.5
2.6
0.32
0.36
iu/ml
0.38
44
56
52
54
10.70
45.60
2.0
1.6
—
—
—
0
0
60
82
8.24
42.54
2.1
1.5
—
—
—
0
0
111
284
4.81
41.30
3.0
1.5
1.26
1.37
g/l
0.25
105
262
53
65
9.06
40.99
2.0
1.5
—
—
—
0
0
153
504
4.02
40.65
2.8
1.8
—
—
—
0
0
157
535
3.90
39.61
2.6
1.8
—
—
—
0
0
124
358
4.34
39.38
5.2
2.9
63.82
67.11
g/l
4.57
117
338
336
1865
3.80
39.28
13.0
5.1
32.25
35.81
g/l
21.19
330
1769
184
702
3.66
39.14
3.1
1.9
—
—
—
0
0
43
43
10.90
38.59
1.4
1.3
—
—
—
0
0
42
42
10.88
37.67
1.8
1.6
—
—
—
0
0
54
79
7.59
35.97
1.2
1.2
—
—
—
0
0
46
56
9.00
35.69
5.8
1.9
34.39
32.55
pg
1.74
46
56
53
77
7.63
35.51
1.2
1.3
275.67
238.49
u/ml
0.28
36
37
50
68
8.11
35.45
1.6
1.6
150.50
165.93
au/ml
0.23
12
23
38
36
11.39
35.31
2.3
1.6
—
—
—
0
0
38
36
11.39
35.31
2.3
1.6
—
—
—
0
0
38
36
11.39
35.31
2.3
1.6
—
—
—
0
0
39
40
10.54
34.32
2.2
2.0
—
—
—
0
0
67
130
5.84
33.93
2.0
1.3
—
—
—
0
0
41
46
9.67
33.82
2.1
1.9
—
—
—
0
0
34
29
12.56
33.75
1.4
1.1
—
—
—
0
0
368
2284
3.79
33.62
24.9
6.8
12.58
11.78
umol/l
0.52
368
2187
378
2397
3.92
33.16
42.3
9.8
3.54
4.11
e9/l
5.28
356
2110
357
2193
3.59
32.72
16.5
6.4
1.46
1.92
e9/l
10.08
333
1931
334
1984
3.35
32.10
20.9
12.2
1.31
1.22
inr
2.44
296
1630
124
411
3.74
31.87
3.9
2.5
0.18
0.21
g/l
4.47
117
389
84
211
4.63
31.52
2.1
1.4
—
—
—
0
0
324
1906
3.24
31.35
18.7
6.5
1.18
1.21
mmol/l
8.35
318
1772
42
54
8.44
31.12
2.0
1.6
—
—
—
0
0
166
673
3.26
30.92
4.1
2.5
2.00
2.33
g/l
9.99
159
629
159
630
3.30
30.75
4.2
2.5
27.85
22.96
%
2.13
152
594
31
27
12.22
30.32
2.5
2.1
545.43
507.52
e6/l
0.09
21
21
124
425
3.60
30.15
8.0
3.8
2.06
1.95
mmol/l
0.12
109
362
281
1550
3.02
30.03
5.7
3.3
—
—
—
0
0
339
2108
3.17
28.55
21.6
7.2
1.19
1.21
mmol/l
4.58
307
1839
325
1984
3.06
28.10
6.7
2.7
—
—
estimate
—
0
0
167
719
3.05
27.57
4.2
2.5
12.87
13.39
umol/l
0.34
161
675
262
1470
2.76
25.80
9.1
3.5
2.31
2.36
mmol/l
5.44
251
1342
207
1035
2.78
25.50
5.9
2.3
—
—
—
0
0
197
962
2.80
25.38
3.7
2.7
4.25
5.77
e6/l
0.89
182
879
61
140
4.86
25.38
6.7
4.4
1.75
1.32
mmol/l
1.09
61
135
128
512
3.06
23.62
13.0
8.1
1.18
0.82
mmol/l
0.40
110
433
61
149
4.55
23.47
2.7
2.9
—
—
—
0
0
249
1412
2.62
23.24
5.2
3.4
25.04
89.56
e6/l
0.77
213
1073
22
0
+∞
23.11
1.4
0.0
—
—
—
0
0
223
1220
2.57
22.14
5.2
3.2
0.44
0.32
e6/l
0.43
188
888
49
107
5.00
21.54
2.0
1.4
—
—
—
0
0
112
438
3.04
21.30
14.7
8.7
109.85
121.47
g/l
6.75
112
430
114
457
2.97
20.70
14.0
8.4
95.27
95.52
%
0.11
114
445
77
245
3.56
20.48
8.0
3.9
24.51
24.46
mmol/l
0.06
77
245
258
1592
2.37
18.68
6.4
4.0
118.94
74.89
e6/l
0.36
217
1119
43
95
4.88
18.61
1.7
1.3
—
—
—
0
0
195
1067
2.41
18.57
3.0
2.2
3.25
2.92
mg/l
1.00
183
940
288
1877
2.38
18.20
35.1
11.3
0.01
0.00
e9/l
0.83
256
1542
229
1362
2.33
17.81
4.2
2.6
54.73
63.43
u/l
0.99
220
1268
24
31
8.10
17.57
2.6
1.6
—
—
—
0
0
51
136
4.08
17.40
4.0
2.2
517.41
682.42
ug/l
0.19
46
125
52
141
4.02
17.34
6.2
3.9
35.07
47.09
mg/l
0.37
41
120
52
141
4.02
17.34
6.2
3.9
57.17
92.07
mg/l
0.36
41
119
76
269
3.18
16.93
15.7
7.3
25.17
24.52
mmol/l
0.57
76
256
173
936
2.34
16.52
4.5
1.7
4.15
1.29
mg/l
2.68
154
739
107
465
2.68
16.37
4.2
4.7
14.01
21.80
ug/l
0.28
90
390
47
128
3.97
15.56
6.4
3.5
4.75
1.91
ratio
0.66
24
72
99
428
2.66
15.22
7.0
3.2
—
—
—
0
0
345
2534
2.35
15.08
14.3
5.0
6.89
6.70
mmol/l
1.07
337
2410
359
2686
2.42
14.97
7.2
4.6
9.33
2069.54
e6/l
—
9
48
215
1315
2.17
14.86
4.5
3.2
1549.83
1012.44
ng/l
1.29
198
1119
50
150
3.61
14.40
3.7
1.9
0.76
1.08
g/l
0.24
39
137
27
52
5.45
13.59
1.1
1.2
—
—
—
0
0
250
1664
2.07
13.39
5.8
3.9
35.07
92.23
ng/l
0.84
212
1213
80
337
2.65
12.83
8.6
2.6
54.33
65.09
ml/min/173m2
1.37
33
146
41
117
3.74
12.69
1.4
1.3
—
—
—
0
0
23
22
10.93
12.38
2.1
1.5
—
—
—
0
0
103
497
2.37
12.36
6.4
2.9
13.02
8.54
umol/l
1.33
96
442
77
324
2.65
12.35
5.5
4.0
125.73
82.33
ng/l
2.20
70
292
197
1241
2.01
11.90
7.6
4.1
0.00
0.01
estimate
0.96
82
429
21
36
6.06
11.89
6.7
2.9
—
—
—
0
0
51
177
3.11
11.64
4.0
1.7
3.87
3.66
g/l
0.13
45
166
51
177
3.11
11.64
4.0
1.7
3.78
4.30
g/l
3.80
45
166
51
177
3.11
11.64
4.0
1.7
7.26
7.45
g/l
0.30
45
166
46
150
3.29
11.63
3.7
1.6
9.77
10.62
g/l
0.54
40
138
42
131
3.42
11.38
3.5
1.6
0.00
0.00
g/l
-0.00
35
123
23
26
9.24
11.38
2.1
1.5
—
—
—
0
0
22
23
9.98
11.36
2.2
1.6
—
—
—
0
0
17
10
17.59
11.27
1.2
1.6
—
—
—
0
0
41
130
3.36
10.83
3.5
1.6
0.00
0.00
g/l
-0.00
34
117
134
769
2.04
10.24
4.7
2.9
1.30
0.90
e6/l
0.89
85
406
35
105
3.52
10.06
1.9
1.2
687.31
469.42
mg/l
1.01
35
97
41
139
3.14
9.72
1.9
1.4
—
—
—
0
0
46
167
2.94
9.70
4.2
1.7
3.20
2.99
g/l
0.50
40
156
267
1949
1.85
9.68
4.5
3.0
474.73
123.66
ug/l
4.23
257
1827
16
13
12.69
9.42
1.4
2.0
—
—
—
0
0
16
13
12.69
9.42
1.4
2.0
—
—
—
0
0
13
6
22.22
9.39
2.0
1.0
248.54
183.67
%
—
13
6
59
252
2.53
9.11
3.8
3.6
2.02
1.82
mmol/l
0.14
45
180
25
64
4.07
8.98
1.9
1.2
3.40
1.28
u/ml
0.90
15
18
25
64
4.07
8.98
2.0
1.2
8.06
3.54
u/ml
0.85
16
26
31
93
3.50
8.92
1.9
1.2
3.71
3.96
mmol/l
0.57
31
85
213
1478
1.81
8.86
7.2
3.4
41.47
33.97
u/l
1.50
204
1403
186
1246
1.81
8.65
2.2
1.7
19.13
20.61
nmol/l
0.71
171
1045
29
85
3.57
8.64
1.4
1.5
—
—
—
0
0
293
2250
1.80
8.51
7.3
3.9
7.86
0.00
estimate
0.49
92
468
20
30
6.91
8.45
1.4
1.4
74825.38
26049.17
e6/l
0.48
13
12
295
2277
1.79
8.35
7.3
3.9
0.07
0.02
estimate
0.43
89
437
289
2232
1.76
8.01
7.4
3.9
0.00
0.00
estimate
0.50
90
460
32
107
3.14
7.77
1.2
1.3
—
—
—
0
0
86
461
2.06
7.73
28.6
6.8
—
—
—
0
0
21
56
3.88
7.16
1.4
1.1
—
—
—
0
0
116
712
1.83
6.95
5.0
3.0
3.57
1.92
e6/l
0.99
67
349
43
185
2.46
6.54
4.6
2.2
12.06
7.50
iu/ml
0.41
13
45
127
1842
0.57
6.53
2.1
2.0
1.48
1.36
mmol/l
0.85
101
1549
10
7
14.56
6.42
1.3
1.4
—
—
—
0
0
108
667
1.80
6.29
1.9
1.7
1337.53
1211.99
nmol/l
0.62
93
516
130
848
1.74
6.27
1.8
1.7
496.53
16318430.25
pmol/l
0.50
119
717
13
17
7.83
6.16
1.2
1.2
—
—
—
0
0
14
21
6.83
6.07
2.6
4.4
82.64
91.29
%
0.40
14
21
9
6
15.25
5.92
1.7
1.0
—
—
—
0
0
30
115
2.72
5.76
1.8
1.1
—
—
—
0
0
9
7
13.07
5.60
1.8
1.4
—
—
—
0
0
22
73
3.11
5.44
1.4
1.4
—
—
—
0
0
22
73
3.11
5.44
1.4
1.4
—
—
—
0
0
32
131
2.55
5.41
1.4
1.4
280.24
279.82
ug/g
0.00
21
83
17
48
3.64
5.37
2.5
1.9
88.15
90.48
%
0.75
17
48
11
14
8.01
5.37
1.0
1.0
—
—
—
0
0
369
4061
0.58
5.29
5.6
6.1
2.57
2.69
mmol/l
1.58
346
3795
33
139
2.48
5.27
1.6
1.6
0.01
0.04
iu/ml
—
8
22
220
1699
1.55
5.18
7.7
3.8
0.00
0.03
estimate
1.64
80
388
29
117
2.58
5.06
1.9
1.1
—
—
—
0
0
28
112
2.59
4.97
4.5
2.9
2.18
1.65
index
0.23
22
63
10
13
7.83
4.87
3.4
1.8
—
—
—
0
0
49
257
2.01
4.65
2.5
1.6
—
—
—
0
0
7
5
14.18
4.59
1.0
1.0
86.00
123.20
%
—
7
5
7
5
14.18
4.59
1.1
1.0
—
—
—
0
0
13
27
4.92
4.53
2.7
1.3
—
—
—
0
0
364
3989
0.61
4.42
5.2
5.2
1.34
1.46
mmol/l
5.97
341
3717
9
12
7.62
4.37
3.7
1.8
—
—
—
0
0
9
12
7.62
4.37
3.7
1.8
—
—
—
0
0
12
24
5.10
4.34
1.1
1.2
—
—
—
0
0
367
4008
0.62
4.25
5.3
5.4
4.41
4.61
mmol/l
2.98
347
3759
355
3905
0.63
4.23
5.6
5.3
6.04
5.99
mmol/l
0.36
329
3625
21
80
2.70
4.12
6.0
3.0
9.23
10.10
pmol/l
0.16
21
80
15
47
3.26
4.09
1.1
1.1
—
—
—
0
0
13
32
4.15
3.93
1.0
1.1
—
—
—
0
0
24
101
2.45
3.88
2.8
1.9
99.97
4581.60
u/l
0.88
16
36
13
34
3.90
3.72
1.2
1.0
—
—
—
0
0
229
1875
1.43
3.60
3.2
2.5
73.87
77.20
nmol/l
0.99
218
1685
65
407
1.69
3.54
3.4
2.4
26.98
33.38
u/l
1.84
55
337
227
1860
1.43
3.54
2.6
2.1
90.19
96.40
pmol/l
1.41
161
949
17
63
2.76
3.53
1.3
1.1
—
—
—
0
0
115
831
1.51
3.44
4.5
4.0
520.75
459.26
ng/l
0.13
100
665
350
3824
0.67
3.39
7.4
6.6
40.00
39.46
mmol/mol
0.51
331
3612
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
9
18
5.08
3.38
3.7
1.6
—
—
—
0
0
18
71
2.60
3.33
1.6
1.4
—
—
—
0
0
346
3078
1.47
3.32
8.0
4.5
18.97
11.91
mm/h
10.23
341
2887
11
28
4.00
3.30
1.3
1.4
—
—
—
0
0
23
105
2.25
3.14
1.2
1.1
—
4.24
—
0
18
9
20
4.57
3.12
2.4
2.5
1020.56
795.90
u/ml
—
9
20
10
25
4.06
3.10
1.2
1.1
—
—
—
0
0
7
13
5.45
2.88
3.9
2.8
0.65
0.60
mmol/l
—
7
13
6
9
6.73
2.87
2.7
2.0
—
—
—
0
0
9
23
3.97
2.78
5.7
2.8
1.00
0.78
index
—
9
23
5
6
8.40
2.75
1.2
1.0
—
—
—
0
0
5
6
8.40
2.75
1.2
1.0
—
—
—
0
0
33
184
1.85
2.69
2.0
1.3
—
—
—
0
0
10
30
3.38
2.61
1.4
1.6
—
—
—
0
0
6
11
5.51
2.55
1.2
1.3
—
—
—
0
0
34
195
1.80
2.54
4.3
3.9
558.32
1540.95
u/ml
0.52
28
164
75
528
1.50
2.52
2.4
1.9
1.82
1.50
%
1.06
61
464
11
37
3.02
2.50
1.1
1.1
—
—
—
0
0
11
39
2.86
2.35
1.2
1.5
—
—
—
0
0
7
18
3.93
2.26
2.7
1.6
54.47
61.43
ug/l
—
7
18
25
137
1.87
2.18
1.4
1.3
1.58
2.79
u/ml
—
6
18
7
19
3.72
2.16
1.1
1.0
1663.43
1370.05
miu/ml
—
7
19
9
30
3.04
2.15
1.1
1.0
—
—
—
0
0
6
14
4.33
2.15
1.2
1.2
—
—
—
0
0
25
138
1.86
2.13
1.4
1.3
4.44
2.69
u/ml
—
7
24
9
31
2.94
2.08
1.6
1.4
—
—
—
0
0
9
31
2.94
2.08
1.6
1.4
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
10
5.04
2.07
1.0
1.1
70.00
99.40
%
—
5
10
5
10
5.04
2.07
1.6
1.1
—
—
—
0
0
43
281
1.58
2.04
1.5
1.2
633.18
229.60
u/ml
0.90
36
263
359
3824
0.74
1.96
4.8
4.4
1.41
1.29
mmol/l
2.27
337
3543
25
416
0.58
1.94
2.3
2.1
3.91
3.47
ratio
0.51
19
341
13
58
2.28
1.92
1.1
1.2
—
—
—
0
0
420
3992
1.48
1.91
58.9
15.9
29.32
23.98
mg/l
2.97
399
3268
23
129
1.82
1.89
1.7
1.6
—
—
—
0
0
122
987
1.32
1.83
7.2
4.0
1.02
1.02
kg/l
0.17
99
650
13
60
2.20
1.79
2.8
1.5
—
—
—
0
0
13
60
2.20
1.79
2.8
1.5
—
—
—
0
0
24
394
0.59
1.78
1.6
2.0
—
—
—
0
0
9
36
2.53
1.75
1.0
1.2
106.89
107.78
pmol/l
—
9
36
13
61
2.16
1.73
2.8
1.5
—
—
—
0
0
5
13
3.87
1.72
1.6
1.2
—
—
—
0
0
5
13
3.87
1.72
1.2
1.1
—
—
—
0
0
20
111
1.84
1.71
1.5
1.2
32.00
45.33
u/ml
—
6
15
13
62
2.13
1.67
2.8
1.5
—
—
—
0
0
10
42
2.41
1.62
1.5
1.3
79.50
44.70
u/l
—
10
37
5
14
3.60
1.62
3.0
4.7
4.48
4.67
kpa
—
5
14
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
5
14
3.60
1.62
3.0
4.7
10.28
10.00
kpa
—
5
14
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
13
63
2.09
1.61
2.8
1.5
—
—
—
0
0
7
27
2.62
1.52
1.7
1.3
—
—
—
0
0
7
27
2.62
1.52
1.7
1.3
—
—
—
0
0
9
38
2.39
1.46
5.8
2.7
8.11
13.39
index
—
9
23
170
1478
1.24
1.39
4.9
4.1
23.00
7.83
mg/mmol
1.93
107
921
23
355
0.63
1.36
1.6
1.9
—
—
—
0
0
5
17
2.96
1.36
3.6
2.5
36.76
42.10
g/l
—
5
17
5
17
2.96
1.36
1.0
1.4
—
—
—
0
0
5
18
2.80
1.29
1.4
1.2
—
—
—
0
0
10
48
2.11
1.28
1.8
1.1
—
—
—
0
0
174
1527
1.22
1.28
4.0
3.4
6.58
7.82
mmol/l
3.92
146
1292
421
4336
0.73
1.27
88.0
24.6
118.62
135.85
g/l
63.61
421
4297
31
212
1.49
1.26
3.1
1.5
0.50
0.32
mg/l
0.67
17
94
144
1242
1.23
1.25
6.7
3.3
0.00
0.01
estimate
0.75
80
370
12
63
1.93
1.24
2.9
1.5
—
—
—
0
0
8
37
2.18
1.22
1.8
1.2
—
—
—
0
0
8
37
2.18
1.22
1.8
1.2
—
—
—
0
0
6
130
0.45
1.17
1.8
1.2
0.89
0.89
g/l
—
6
130
8
39
2.07
1.15
1.8
1.3
1.01
1.20
promille
—
8
31
5
20
2.52
1.15
2.8
2.0
60.60
50.57
umol/l
—
5
15
104
1223
0.81
1.13
4.1
4.5
21.41
21.29
%
0.03
54
566
23
152
1.54
1.11
2.8
1.8
—
—
—
0
0
18
112
1.63
1.10
1.3
1.4
309.34
254.73
miu/ml
—
7
53
18
113
1.62
1.07
1.3
1.3
—
—
—
0
0
356
3724
0.82
1.05
5.9
5.3
2.17
1.92
mu/l
1.67
333
3442
5
22
2.29
1.03
1.4
1.1
—
—
—
0
0
64
784
0.79
1.00
1.4
1.3
18.77
31.87
iu/ml
1.55
25
246
9
50
1.82
0.97
3.6
3.9
—
—
—
0
0
24
338
0.69
0.96
1.3
1.4
—
—
—
0
0
77
918
0.81
0.95
2.6
3.2
0.77
0.75
ug/l
0.10
51
581
6
27
2.24
0.93
1.2
8.0
—
84.10
—
0
10
22
305
0.71
0.82
1.6
1.8
3.36
3.48
mmol/l
0.15
17
230
110
963
1.19
0.81
1.2
1.3
3.10
1.45
u/ml
0.38
31
270
17
114
1.51
0.80
1.5
1.3
—
—
—
0
0
257
2411
1.15
0.75
3.4
2.9
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
5
24
2.09
0.74
9.4
4.3
264.40
154.96
nmol/l
—
5
24
5
25
2.01
0.73
1.4
1.4
1.00
1.35
u/field
—
5
17
9
58
1.56
0.70
1.3
1.0
—
—
—
0
0
7
43
1.64
0.67
1.0
1.1
—
94.40
—
0
5
293
2788
1.13
0.65
6.3
3.4
84.71
51.55
u/l
3.71
283
2633
63
735
0.84
0.65
1.3
1.3
38.93
13.47
u/ml
0.72
23
289
20
148
1.37
0.60
2.0
1.7
—
—
—
0
0
14
196
0.71
0.58
1.1
1.0
—
—
—
0
0
8
53
1.52
0.58
1.9
1.7
—
—
—
0
0
10
149
0.66
0.57
1.6
2.2
—
—
—
0
0
44
522
0.83
0.55
4.9
5.0
27.82
32.11
%
1.70
33
344
76
669
1.16
0.55
1.5
1.5
—
—
—
0
0
34
278
1.24
0.53
1.3
1.4
—
57.37
—
0
23
140
1513
0.89
0.51
5.1
5.3
2.25
2.27
ug/l
0.01
129
1373
13
177
0.73
0.48
1.5
2.2
—
—
—
0
0
14
102
1.38
0.48
1.6
1.5
—
—
—
0
0
10
72
1.40
0.37
1.1
1.1
—
15.98
—
0
21
14
108
1.31
0.35
2.1
2.5
64.63
68.01
ug/min
—
8
62
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
6
47
1.28
0.32
1.3
1.5
67.47
28.66
u/l
—
6
39
7
53
1.33
0.31
1.6
1.6
—
—
—
0
0
9
116
0.77
0.27
1.3
1.5
—
—
—
0
0
385
3902
0.93
0.23
49.2
15.5
77.55
80.67
ml/min/173m2
1.68
377
3632
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
53
1.13
0.18
1.2
1.2
1863.17
271.07
pmol/l
—
6
45
7
60
1.17
0.18
10.7
2.1
10.00
10.84
mmol/l
—
7
60
17
154
1.11
0.10
2.0
1.9
41.59
41.16
nmol/l
0.03
17
147
5
48
1.04
0.09
1.6
1.5
72.68
52.93
ug/l
—
5
48
11
122
0.90
0.07
2.5
1.9
170.73
214.78
pmol/l
0.94
11
114
11
100
1.10
0.05
1.0
1.1
—
7.71
—
0
12
27
282
0.95
0.04
1.1
1.2
144.26
118.68
u/ml
0.11
14
110
54
553
0.97
0.04
1.4
1.5
—
—
—
0
0
312
3106
1.01
0.03
5.1
4.3
15.07
14.80
pmol/l
1.07
290
2844
14
132
1.06
0.02
1.7
1.7
707.84
966.98
mu/l
—
8
110
13
129
1.01
0.00
1.6
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1.19
—
0
7
11
110
1.00
-0.00
1.5
1.7
251.55
277.77
mu/l
0.30
11
104
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
5.92
—
0
5
5
57
0.88
-0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.6
—
10.76
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.6
1.3
6.64
7.42
mmol/l
—
5
48
7
69
1.01
-0.00
1.6
1.7
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.3
0.62
0.58
nmol/l
—
5
54
Mortality – FinRegistry
↥Association
Association between endpoint D3_SCNDTHROMBOCYTOPENIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDTHROMBOCYTOPENIA | 6.962 [5.14, 9.44] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.753 |
During the follow-up period (1.1.1998 — 31.12.2019), 515 out of 941 females with D3_SCNDTHROMBOCYTOPENIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDTHROMBOCYTOPENIA | 6.625 [4.83, 9.08] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 505 out of 932 males with D3_SCNDTHROMBOCYTOPENIA died.
Mortality risk
Mortality risk for people of age
years, who have D3_SCNDTHROMBOCYTOPENIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.688% | 0.814% |
| 5 | 4.254% | 6.786% |
| 10 | 9.942% | 17.034% |
| 15 | 19.081% | 30.032% |
| 20 | 33.067% | 46.714% |
Relationships between endpoints
↥Index endpoint: D3_SCNDTHROMBOCYTOPENIA – Secondary thrombocytopenia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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