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Alzheimer’s disease (undefined)

DOID Endpoint Browser

AD_U

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F009&G309
  • Cause of death: ICD-10 — F009&G309

2 out of 7 registries used, show all original rules.

581

4. Check minimum number of events

None

581

5. Include endpoints

None

581

6. Filter based on genotype QC (FinnGen only)

504

Control definitions (FinnGen only)

Control exclude
G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 504 222 282
Unadjusted period prevalence (%) 0.11 0.08 0.13
Median age at first event (years) 80.37 82.22 78.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
517
Matched controls
5170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
993.6
307.7
314
8
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
280.1
307.7
398
61
F009, G309,
ICD-10 Finland
+∞
307.7
510
*
N06DA02
ATC
donepezil; oral
40.4
307.7
252
119
G30.1
ICD-10 Finland
Alzheimer disease with late onset
119.4
307.7
273
48
N06DX01
ATC
memantine; oral
39.8
307.7
281
150
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
72.8
258.8
143
27
N06DA03
ATC
rivastigmine; oral, transdermal
26.3
204.1
154
82
N05AX08
ATC
risperidone; systemic
11.8
159.9
211
286
G30.8
ICD-10 Finland
Other Alzheimer disease
62.9
118.0
66
12
F0019, G301,
ICD-10 Finland
+∞
110.5
102
*
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
56.5
89.4
51
10
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
273.6
71.2
71
*
N05AH04
ATC
quetiapine; oral
6.3
70.4
144
297
N06DA04
ATC
galantamine; oral
15.2
67.6
62
46
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
62.8
59
*
F0009, G300,
ICD-10 Finland
+∞
58.5
55
*
F03
ICD-10 Finland
Unspecified dementia
5.2
57.4
147
366
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
14.9
54.3
50
37
P70
ICPC
Dementia
9.4
49.1
62
74
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
102.4
35.2
38
*
N06AB04
ATC
citalopram; systemic
3.0
26.9
159
669
N05BA04
ATC
oxazepam; oral
2.7
24.1
183
871
N03AG01
ATC
valproic acid; systemic, rectal
6.4
23.8
41
69
G30
ICD-10 Finland
Alzheimer disease
35.3
23.6
30
9
Z75.5
ICD-10 Finland
Holiday relief care
6.0
21.5
39
69
N05AH03
ATC
olanzapine; systemic
7.7
21.0
30
41
F0029, G308,
ICD-10 Finland
+∞
21.0
20
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.3
20.2
84
284
Z02.4
ICD-10 Finland
Examination for driving licence
0.1
19.7
7
659
N05AD03
ATC
melperone; systemic
4.8
18.6
44
99
N05AD01
ATC
haloperidol; systemic
3.8
15.9
51
145
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.5
14.2
52
161
N06AB10
ATC
escitalopram; oral
2.8
13.5
73
285
WYA20
NOMESCO Finland
Home visit
4.4
13.4
34
81
N05BA06
ATC
lorazepam; systemic, sublingual
3.2
12.6
52
174
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
133.1
12.5
13
*
R53
ICD-10 Finland
Malaise and fatigue
2.1
12.3
166
966
S18
ICPC
Laceration/cut
0.3
12.0
42
1109
R41.0
ICD-10 Finland
Disorientation, unspecified
3.4
11.6
43
134
SPAT1251
SPAT
Organisation of medication
3.1
10.9
47
161
N02AJ06
ATC
codeine and paracetamol; systemic
0.2
10.7
15
680
A06AD11
ATC
lactulose; oral
1.9
10.7
171
1049
F0014, G301,
ICD-10 Finland
+∞
10.4
10
*
A98
ICPC
Health maint/preventive medicine
0.5
10.2
153
2309
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.4
9.6
35
108
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
9.4
37
120
N07AA05, ,
ATC
+∞
9.4
9
*
H81
ICPC
Excessive ear wax
0.2
9.4
12
580
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
37.4
9.0
11
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
9.0
218
1505
N06AX11
ATC
mirtazapine; oral
1.9
8.9
148
911
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.1
8.9
24
60
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
8.6
21
683
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.9
234
1694
E000001, ,
ATC
2.0
7.8
94
517
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.1
7.4
20
50
130
Kela drug reimbursment
Malignant tumour
0.2
7.1
8
354
Z71.8
ICD-10 Finland
Other specified counselling
0.3
7.1
17
563
B01AF02
ATC
apixaban; oral
0.2
7.0
11
468
H13
ICPC
Plugged feeling ear
0.3
7.0
19
587
P20
ICPC
Memory disturbance
1.9
7.0
94
537
C04AE01
ATC
ergoloid mesylates; systemic
4.1
6.9
19
48
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.1
6.9
*
228
M79.6
ICD-10 Finland
Pain in limb
0.4
6.9
45
932
SPAT1043
SPAT
Audiometry
0.2
6.7
7
326
DFF00
NOMESCO Finland
Pure tone audiometry
0.1
6.7
*
247
SPAT1153
SPAT
Removal of sutures
0.4
6.7
31
738
L17
ICPC
Foot/toe symptom/complaint
0.3
6.6
21
599
F51.0
ICD-10 Finland
Nonorganic insomnia
0.1
6.5
*
190
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
0.3
6.5
19
564
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.4
6.4
44
193
M25.5
ICD-10 Finland
Pain in joint
0.3
6.3
13
469
H02
ICPC
Hearing complaint
0.2
6.3
10
423
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
18.3
6.3
9
5
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
6.3
6
*
F009, G308,
ICD-10 Finland
+∞
6.3
6
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.2
6.2
10
419
F05.1
ICD-10 Finland
Delirium superimposed on dementia
8.7
6.1
12
14
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
0.1
6.0
*
229

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
1967
0.28
25.48
3.2
5.3
2.20
2.31
mmol/l
0.58
55
1688
70
1884
0.27
24.63
3.0
4.6
4.04
4.15
mmol/l
0.52
53
1627
70
1861
0.28
23.85
2.9
4.5
1.33
1.40
mmol/l
0.70
53
1588
68
1791
0.29
22.31
2.6
3.9
1.43
1.21
mmol/l
1.19
51
1510
98
2031
0.36
18.88
6.4
5.3
6.78
6.25
mmol/l
1.28
65
1733
43
1336
0.26
17.90
7.0
6.6
4.74
4.69
e9/l
0.03
35
1127
31
1161
0.22
17.52
3.4
4.4
0.58
0.66
e9/l
0.83
26
969
99
1995
0.38
17.44
6.8
7.2
47.37
42.02
mmol/mol
2.51
75
1761
32
1169
0.23
17.35
3.3
4.4
0.04
0.04
e9/l
0.38
27
978
35
1205
0.24
17.20
4.0
4.5
0.16
0.19
e9/l
0.57
29
1013
35
1200
0.24
17.06
3.3
4.7
1.53
1.64
e9/l
0.60
28
1036
64
1528
0.34
15.77
5.0
5.5
1.22
1.21
mmol/l
0.26
45
1260
101
1922
0.41
14.70
4.7
6.5
88.72
87.05
u/l
0.10
83
1779
78
1651
0.38
14.52
4.1
4.5
7.89
7.03
mmol/l
1.96
71
1565
35
1106
0.27
14.41
2.9
3.0
128.21
151.35
ug/l
0.44
29
984
50
1303
0.32
14.39
2.2
2.4
99.27
89.98
pmol/l
0.92
23
711
132
2248
0.45
14.35
6.4
10.8
19.62
23.41
u/l
1.38
109
2132
107
1974
0.42
14.28
3.8
5.0
2.05
2.16
mu/l
0.28
82
1716
60
1421
0.35
14.18
4.5
4.8
12.24
13.67
umol/l
0.36
51
1334
80
1618
0.40
13.01
3.4
3.9
15.30
15.40
pmol/l
0.13
64
1404
54
1300
0.35
12.96
3.1
3.7
3176.44
3251.30
ng/l
0.03
41
1141
57
1318
0.36
12.45
4.2
5.2
1.22
1.21
mmol/l
0.54
50
1173
37
1005
0.32
11.05
12.7
13.4
0.00
0.01
e9/l
1.01
28
807
47
1120
0.36
10.66
2.1
2.9
—
—
estimate
—
0
0
23
791
0.26
10.54
5.2
3.7
6.33
13.85
mg/mmol
1.76
12
522
66
1348
0.41
10.45
3.2
4.1
31.87
32.97
g/l
0.57
51
1227
108
1808
0.49
9.84
5.0
5.6
—
3.60
—
0
5
29
847
0.30
9.83
2.0
2.5
—
—
—
0
0
26
802
0.29
9.75
4.0
4.5
—
—
—
0
0
23
742
0.28
9.32
3.4
3.0
6.50
6.15
mmol/l
0.27
16
598
24
750
0.29
9.16
3.3
2.9
92.82
70.94
mg/l
0.17
13
515
41
979
0.37
9.14
2.2
2.5
2.78
3.33
mg/l
1.26
30
835
151
2239
0.54
9.10
16.2
21.4
—
—
—
0
0
104
1702
0.51
8.48
18.3
28.4
14.31
14.48
%
0.63
94
1666
44
985
0.40
8.38
2.6
2.8
2.37
2.35
mmol/l
0.54
31
876
22
686
0.29
8.31
7.0
6.0
—
—
—
0
0
50
1055
0.42
8.24
3.8
4.1
60.64
138.75
e6/l
0.57
39
859
37
887
0.37
8.22
1.5
2.7
—
—
—
0
0
21
659
0.29
8.00
2.1
2.8
390.62
392.51
umol/l
0.02
13
544
38
889
0.38
7.96
3.9
3.6
7.40
7.40
ph
0.52
30
658
12
514
0.22
7.73
2.3
2.5
23.00
19.66
%
—
7
474
43
937
0.41
7.59
2.1
2.0
347.84
270.59
u/l
0.30
31
872
171
2368
0.58
7.43
20.3
33.7
123.33
124.16
g/l
0.27
152
2309
41
904
0.41
7.43
3.6
4.0
0.78
0.58
e6/l
0.31
33
734
171
2367
0.59
7.41
19.8
33.4
239.07
231.63
e9/l
0.64
149
2285
171
2367
0.59
7.41
19.9
33.4
92.32
92.13
fl
0.15
152
2301
171
2367
0.59
7.41
19.9
33.4
4.08
4.14
e12/l
0.70
150
2276
171
2367
0.59
7.41
20.1
33.8
36.65
36.89
%
0.15
151
2298
171
2367
0.59
7.41
19.9
33.3
30.43
30.28
pg
0.36
152
2301
16
561
0.26
7.40
1.9
2.4
2.23
2.16
g/l
—
9
508
171
2361
0.59
7.29
16.9
28.9
4.05
4.06
mmol/l
0.10
151
2280
171
2361
0.59
7.29
16.8
28.7
140.08
139.10
mmol/l
2.34
151
2280
173
2367
0.60
7.00
17.5
30.8
90.72
95.48
umol/l
1.15
152
2291
40
869
0.42
6.95
3.2
6.2
27.30
10.66
ug/l
0.35
35
752
11
460
0.22
6.80
1.9
1.8
30.71
29.87
s
0.32
11
445
168
2304
0.60
6.78
15.5
23.2
40.28
31.52
mg/l
1.28
138
2065
175
2370
0.60
6.66
19.7
33.4
7.87
7.48
e9/l
0.90
153
2274
106
1633
0.56
6.62
19.3
25.2
1.61
1.53
inr
0.62
91
1436
27
679
0.36
6.54
3.3
3.0
2.50
2.48
mmol/l
0.34
17
584
38
824
0.42
6.53
3.7
4.1
—
0.00
estimate
—
0
12
62
1121
0.49
6.51
3.8
4.7
64.79
261.83
e6/l
2.32
39
885
114
1712
0.57
6.44
17.6
30.3
328.68
328.21
g/l
0.21
105
1674
26
649
0.37
6.18
4.1
4.7
170.40
169.52
ng/l
0.00
21
607
14
468
0.28
5.92
2.6
3.9
—
—
—
0
0
7
296
0.23
5.78
1.1
2.1
63.14
64.94
g/l
—
7
261
43
835
0.47
5.45
3.0
2.4
50.87
63.09
u/l
1.11
38
764
8
304
0.25
5.42
1.1
1.5
—
—
—
0
0
86
1342
0.57
5.39
4.8
5.4
0.00
0.00
estimate
-0.00
18
350
78
1238
0.56
5.17
3.7
4.4
—
—
—
0
0
0
128
0.00
5.16
0.0
1.6
—
—
—
0
0
12
404
0.28
5.14
1.6
4.5
4.17
1.32
mmol/l
—
6
304
8
293
0.26
5.12
1.5
4.5
1.64
1.52
mmol/l
—
8
282
22
539
0.38
4.98
1.3
1.6
1.07
1.62
mg/l
1.33
17
433
89
1348
0.59
4.90
3.9
5.1
51.20
109.83
ng/l
0.71
61
1123
40
769
0.48
4.89
4.7
3.6
549.60
516.48
mosm/kgh2o
0.85
35
676
38
742
0.47
4.86
1.9
1.8
435.83
453.20
pmol/l
0.15
23
590
87
1320
0.59
4.81
4.8
5.4
0.00
0.00
estimate
-0.00
18
342
6
249
0.23
4.76
1.0
2.0
—
—
—
0
0
89
1336
0.60
4.69
4.7
5.4
0.00
4.45
estimate
0.50
20
365
8
281
0.27
4.68
1.3
1.3
—
—
—
0
0
68
1089
0.57
4.58
3.2
4.5
—
—
—
0
0
20
492
0.38
4.57
2.9
3.6
2.97
2.19
e6/l
0.36
15
273
20
489
0.39
4.51
1.2
1.3
—
—
—
0
0
0
113
0.00
4.42
0.0
1.5
—
—
—
0
0
5
217
0.22
4.20
1.2
1.4
—
—
—
0
0
74
1070
0.64
3.16
4.6
4.7
6.43
6.39
ph
0.09
47
597
50
789
0.59
3.10
2.1
1.8
1353.63
1146.82
nmol/l
0.59
30
591
8
224
0.35
3.00
1.5
1.9
0.18
0.17
g/l
—
8
194
0
80
0.00
2.94
0.0
1.3
—
55.25
—
0
61
6
189
0.31
2.86
1.8
1.3
—
—
—
0
0
22
425
0.50
2.73
2.2
3.8
—
—
—
0
0
11
276
0.39
2.68
3.5
2.6
0.14
1.05
e6/l
1.72
11
265
0
70
0.00
2.61
0.0
1.3
—
262.31
—
0
63
6
174
0.34
2.45
2.3
6.3
93.25
93.84
%
—
6
174
17
344
0.48
2.43
2.1
2.7
15.03
6.14
ug/l
—
10
273
24
433
0.53
2.42
1.5
1.9
—
—
—
0
0
7
184
0.37
2.33
2.3
2.8
—
—
—
0
0
0
61
0.00
2.25
0.0
1.1
—
—
—
0
0
5
149
0.33
2.18
1.0
1.3
—
—
—
0
0
5
151
0.32
2.18
1.6
2.1
—
—
—
0
0
0
55
0.00
2.08
0.0
1.3
—
—
—
0
0
79
1035
0.72
1.94
4.9
5.7
0.00
0.10
estimate
2.79
14
283
5
142
0.35
1.90
2.0
3.2
—
—
—
0
0
0
51
0.00
1.89
0.0
1.3
—
8.64
—
0
10
0
53
0.00
1.88
0.0
1.0
—
—
—
0
0
6
152
0.39
1.79
2.2
4.3
—
—
—
0
0
5
136
0.36
1.78
1.0
1.3
—
—
—
0
0
61
806
0.72
1.58
5.0
5.1
0.00
0.01
estimate
0.50
15
282
0
44
0.00
1.52
0.0
1.2
—
3.54
—
0
5
13
239
0.53
1.46
1.2
3.0
104.60
102.33
ng/l
—
5
199
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
9
179
0.49
1.42
1.3
1.2
—
—
—
0
0
22
347
0.62
1.41
1.5
1.9
—
—
—
0
0
5
120
0.41
1.39
1.0
1.3
—
—
—
0
0
14
239
0.57
1.24
1.7
3.0
—
—
—
0
0
57
726
0.76
1.17
4.3
5.1
0.00
0.03
estimate
1.23
15
248
0
34
0.00
1.16
0.0
1.6
—
8.00
—
0
34
0
34
0.00
1.16
0.0
2.4
—
—
—
0
0
0
35
0.00
1.15
0.0
1.1
—
32.94
—
0
30
5
108
0.46
1.02
1.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
3.8
—
28.49
—
0
24
0
30
0.00
0.97
0.0
2.5
—
59.46
—
0
25
0
32
0.00
0.95
0.0
1.7
—
14.09
—
0
32
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
48
603
0.78
0.91
4.5
5.8
1.02
1.02
kg/l
0.05
31
408
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
10
158
0.63
0.71
6.8
5.4
—
—
—
0
0
7
42
1.68
0.68
3.1
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.7
—
9.30
—
0
22
0
23
0.00
0.58
0.0
1.4
—
20.82
—
0
23
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
9.89
—
0
9
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.9
—
6.15
—
0
16
0
18
0.00
0.40
0.0
1.3
—
0.21
—
0
11
0
18
0.00
0.40
0.0
1.2
—
3.71
—
0
18
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
5
77
0.65
0.36
1.0
1.2
—
—
—
0
0
9
126
0.71
0.35
1.2
1.3
—
—
—
0
0
5
39
1.28
0.23
1.0
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
0.87
—
0
11
0
11
0.00
0.21
0.0
1.3
—
1.18
—
0
11
0
11
0.00
0.21
0.0
6.1
—
8.05
—
0
11
0
11
0.00
0.21
0.0
1.2
—
5.40
—
0
5
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
68.17
—
0
6
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
43.40
—
0
5
0
12
0.00
0.21
0.0
1.7
—
327.25
—
0
12
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
81.92
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
28.15
—
0
14
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
45.39
—
0
14
6
49
1.23
0.20
2.2
2.9
11.57
14.74
pmol/l
—
6
49
22
226
0.97
0.00
4.9
5.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
7.87
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
0.00
3.1
5.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
48.54
—
0
8
0
7
0.00
-0.00
0.0
1.6
—
111.57
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
100.57
—
0
7
5
51
0.98
-0.00
4.2
2.6
72.00
62.84
%
—
5
51
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
25.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
190.40
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
72.32
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
2.16
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
43.14
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
1.50
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
14.71
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.7
1.6
10719.67
22676.14
e6/l
—
6
44
0
6
0.00
-0.00
0.0
1.3
—
0.57
—
0
6
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
4.00
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
79.86
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
120.17
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
0.83
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: AD_U – Alzheimer’s disease (undefined)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).