No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- G6_AD_STRICT, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (undefined), excluding more controls
based on the number of shared cases.
Similar with more cases:
- Alzheimer’s disease (undefined)
- Dementia in Alzheimer disease
- Alzheimer disease, excluding more controls
- Alzheimer disease
- Degenerative diseases of the nervous system
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 504 | 222 | 282 |
| Unadjusted period prevalence (%) | 0.11 | 0.08 | 0.13 |
| Median age at first event (years) | 80.37 | 82.22 | 78.91 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 516
- Matched controls
- 4976
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N05AX08
ATC
risperidone; systemic
52.3
307.7
211
65
N06DX01
ATC
memantine; oral
494.6
307.7
281
12
F009, G309,
ICD-10 Finland
+∞
307.7
509
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
307.7
398
*
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
+∞
307.7
313
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
798.3
303.1
273
7
N06DA02
ATC
donepezil; oral
1164.4
280.6
252
*
F03
ICD-10 Finland
Unspecified dementia
61.5
249.4
147
32
N05AH04
ATC
quetiapine; oral
30.2
198.6
144
63
N06DA03
ATC
rivastigmine; oral, transdermal
696.6
162.6
154
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
946.5
151.6
143
*
F0019, G301,
ICD-10 Finland
+∞
109.0
102
*
P70
ICPC
Dementia
37.6
95.7
62
18
N06AB04
ATC
citalopram; systemic
6.8
79.8
159
308
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
417.9
75.9
75
*
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
74.9
71
*
S06.0
ICD-10 Finland
Concussion
29.2
74.5
52
19
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
10.4
69.0
84
91
G30.8
ICD-10 Finland
Other Alzheimer disease
242.6
64.9
66
*
N06DA04
ATC
galantamine; oral
675.6
63.4
62
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
62.0
59
*
N05BA04
ATC
oxazepam; oral
4.8
59.7
183
508
F0009, G300,
ICD-10 Finland
+∞
57.7
55
*
N05AD03
ATC
melperone; systemic
21.0
55.7
44
22
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
53.4
51
*
Z75.5
ICD-10 Finland
Holiday relief care
21.3
49.8
39
19
N06AB10
ATC
escitalopram; oral
7.0
43.5
73
115
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
66.5
43.3
50
8
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
97.2
41.9
46
5
R53
ICD-10 Finland
Malaise and fatigue
3.8
40.8
166
550
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
112.8
39.8
43
*
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
39.6
38
*
N06AX11
ATC
mirtazapine; oral
3.9
38.8
148
467
N03AG01
ATC
valproic acid; systemic, rectal
142.8
38.7
41
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
9.4
38.7
49
55
R41.0
ICD-10 Finland
Disorientation, unspecified
10.4
36.9
43
43
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
36.4
35
*
WYA20
NOMESCO Finland
Home visit
13.4
34.6
34
26
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.2
34.5
218
936
P20
ICPC
Memory disturbance
4.5
33.5
94
235
G30
ICD-10 Finland
Alzheimer disease
+∞
31.2
30
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
6.8
31.1
52
81
N05AD01
ATC
haloperidol; systemic
6.8
30.6
51
79
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
9.8
30.5
37
39
N05BA06
ATC
lorazepam; systemic, sublingual
6.4
29.7
52
85
A06AD11
ATC
lactulose; oral
2.9
27.2
171
716
N05AH03
ATC
olanzapine; systemic
43.7
24.4
30
7
AA1AD
NOMESCO Finland
CT of head and brain
3.1
23.3
116
422
F05.9
ICD-10 Finland
Delirium, unspecified
231.7
22.5
23
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
21.9
234
1251
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
+∞
21.7
21
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
21.7
21
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
22.6
21.5
31
14
F0029, G308,
ICD-10 Finland
+∞
20.7
20
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
200.2
19.4
20
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.9
19.3
31
46
G20
ICD-10 Finland
Parkinson disease
+∞
18.6
18
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
+∞
18.6
18
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
18.6
18
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.1
18.6
7
613
F32.9
ICD-10 Finland
Depressive episode, unspecified
28.1
18.5
25
9
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
189.8
18.4
19
*
SPAT1251
SPAT
Organisation of medication
4.5
18.1
47
109
G40.9
ICD-10 Finland
Epilepsy, unspecified
+∞
17.6
17
*
B01AC07
ATC
dipyridamole; systemic
3.4
17.5
69
216
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
17.4
114
476
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.2
15.9
44
107
G47.3
ICD-10 Finland
Sleep apnoea
24.5
15.8
22
9
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
15.7
112
486
F06.7
ICD-10 Finland
Mild cognitive disorder
14.6
15.6
26
18
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
14.8
135
654
S72.0
ICD-10 Finland
Fracture of neck of femur
3.2
14.6
62
203
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
14.4
14
*
N05CD07
ATC
temazepam; oral
2.4
14.0
116
537
A10AB05
ATC
insulin aspart; parenteral
3.8
13.6
44
120
R41.3
ICD-10 Finland
Other amnesia
20.0
13.6
20
10
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
+∞
13.4
13
*
F22.0
ICD-10 Finland
Delusional disorder
+∞
13.4
13
*
N06AB06
ATC
sertraline; oral
5.6
13.3
26
47
N02BE01
ATC
paracetamol; systemic, rectal
2.1
12.8
353
2550
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.1
12.8
25
25
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.8
12.6
68
255
J01DB01
ATC
cefalexin; oral
2.0
12.4
303
2087
N05AA02
ATC
levomepromazine; systemic
5.2
12.4
26
50
F01.9
ICD-10 Finland
Vascular dementia, unspecified
31.8
12.4
16
5
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
12.4
12
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
12.4
12
*
N03AF01
ATC
carbamazepine; oral, rectal
5.0
12.4
27
54
130
Kela drug reimbursment
Malignant tumour
0.2
11.8
8
467
R55
ICD-10 Finland
Syncope and collapse
2.6
11.8
74
299
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
46.1
11.7
14
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
5.0
11.5
25
50
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
11.3
11
*
J01CA08
ATC
pivmecillinam; oral
1.9
11.3
201
1236
E000001, ,
ATC
2.3
11.2
94
434
E86
ICD-10 Finland
Volume depletion
4.4
10.7
27
61
F0014, G301,
ICD-10 Finland
+∞
10.3
10
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.7
10.3
24
51
W19
ICD-10 Finland
Unspecified fall
2.8
9.8
50
181
N05AB03
ATC
perphenazine; systemic, rectal
16.5
9.7
15
9
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.6
198
1261
N30.9
ICD-10 Finland
Cystitis, unspecified
3.0
9.3
42
142
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
98.2
9.3
10
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
+∞
9.3
9
*
N07AA05, ,
ATC
+∞
9.3
9
*
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
+∞
9.3
9
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
9.2
120
656
N05CF01
ATC
zopiclone; oral
1.8
8.9
180
1133
H02AA02
ATC
fludrocortisone; oral
15.4
8.9
14
9
N30.0
ICD-10 Finland
Acute cystitis
2.3
8.8
73
334
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.0
8.8
40
136
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
+∞
8.2
8
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
8.2
8
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
8.2
8
*
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.3
8.0
62
275
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
8.0
59
256
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
8.0
176
1132
SPAT1254
SPAT
Administration of medicine
2.1
7.9
81
404
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
7.8
37
129
-, ,
ICD-10 Finland
4.5
7.8
19
42
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
44.1
7.6
9
*
C04AE01
ATC
ergoloid mesylates; systemic
6.3
7.5
19
30
G56.0
ICD-10 Finland
Carpal tunnel syndrome
7.9
7.4
16
20
N06AA09
ATC
amitriptyline; systemic
2.9
7.4
36
127
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.3
93
501
H81
ICPC
Excessive ear wax
0.2
7.3
12
480
R42
ICD-10 Finland
Dizziness and giddiness
1.9
7.2
98
540
N06AA12
ATC
doxepin; systemic
3.1
7.2
31
102
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
7.2
7
*
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
7.2
7
*
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
+∞
7.2
7
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
7.2
7
*
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
3.2
7.2
29
92
A10AE04
ATC
insulin glargine; parenteral
2.5
7.1
45
182
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.1
66
316
N02AJ06
ATC
codeine and paracetamol; systemic
0.3
7.1
15
514
S18
ICPC
Laceration/cut
0.4
7.1
42
868
N06AX21
ATC
duloxetine; oral
3.7
7.0
22
59
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.9
6.9
33
116
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.8
77
398
SPAT1053
SPAT
Memory test
2.1
6.8
69
343
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
6.7
70
351
SPAT1229
SPAT
Assessment of need for aid
2.6
6.7
39
152
M02AA07
ATC
piroxicam; topical
1.7
6.7
183
1237
G72.8
ICD-10 Finland
Other specified myopathies
39.2
6.7
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.2
6.7
13
14
K90
ICPC
Stroke/cerebrovascular accident
16.4
6.6
10
6
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.1
6.6
*
210
S70.0
ICD-10 Finland
Contusion of hip
3.0
6.5
28
92
-2, ,
ICPC
7.7
6.5
14
18
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.2
6.4
17
40
SPAT1104
SPAT
Monitoring of emergency patient
2.9
6.4
30
104
M01AH02
ATC
rofecoxib; oral
2.0
6.4
69
351
SPAT1216
SPAT
Assessment of functional ability
2.0
6.4
72
372
P72
ICPC
Schizophrenia
68.2
6.3
7
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
6.3
73
380
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.2
6.3
55
257
B01AF02
ATC
apixaban; oral
0.2
6.3
11
422
J01EA01
ATC
trimethoprim; systemic
1.7
6.2
149
969
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
6.2
6
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
+∞
6.2
6
*
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
6.2
6
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
6.2
6
*
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
6.2
6
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
6.2
6
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
6.2
6
*
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
6.2
6
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
6.2
6
*
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
6.2
6
*
G45.3
ICD-10 Finland
Amaurosis fugax
+∞
6.2
6
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
6.2
6
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
6.2
6
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
6.2
6
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
+∞
6.2
6
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
6.2
6
*
F009, G308,
ICD-10 Finland
+∞
6.2
6
*
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
6.2
6
*
A98
ICPC
Health maint/preventive medicine
0.6
6.0
153
2034
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
6.0
21
552
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
1748
0.31
20.29
3.2
5.1
2.20
2.41
mmol/l
1.56
55
1472
70
1681
0.31
19.98
3.0
4.3
4.04
4.26
mmol/l
1.32
53
1435
70
1652
0.32
19.05
2.9
4.3
1.33
1.41
mmol/l
0.83
53
1381
68
1576
0.33
17.41
2.6
3.7
1.43
1.21
mmol/l
1.25
51
1307
98
1830
0.40
14.93
6.4
5.2
6.78
6.15
mmol/l
1.65
65
1521
43
1184
0.29
14.80
7.0
7.2
4.74
4.77
e9/l
0.02
35
972
99
1741
0.44
12.19
6.8
6.8
47.37
41.16
mmol/mol
3.17
75
1493
106
1788
0.46
11.44
15.0
21.5
62.30
59.86
ml/min/173m2
0.60
91
1640
35
943
0.31
11.03
2.9
3.0
128.21
149.91
ug/l
0.41
29
816
79
1470
0.43
10.94
2.7
3.7
19.22
20.62
mm/h
0.22
65
1300
60
1239
0.40
10.68
4.5
5.3
12.24
14.25
umol/l
0.56
51
1152
64
1281
0.41
10.54
5.0
5.8
1.22
1.20
mmol/l
0.52
45
1059
132
2026
0.50
10.54
6.4
10.5
19.62
21.79
u/l
0.79
109
1897
50
1109
0.37
10.44
2.2
2.2
99.27
91.04
pmol/l
0.77
23
568
101
1691
0.47
10.37
4.7
6.8
88.72
91.46
u/l
0.18
83
1541
107
1728
0.49
9.71
3.8
4.5
2.05
2.24
mu/l
0.54
82
1454
35
888
0.33
9.63
2.0
2.1
73.83
81.43
nmol/l
0.97
23
730
23
726
0.27
9.57
5.2
3.8
6.32
14.44
mg/mmol
1.82
12
448
54
1082
0.42
8.61
3.1
3.5
3176.44
3140.25
ng/l
0.01
41
936
47
994
0.40
8.53
2.1
3.2
—
—
estimate
—
0
0
57
1114
0.43
8.52
4.2
5.3
1.22
1.20
mmol/l
1.08
50
996
78
1344
0.48
8.22
4.1
3.9
7.89
7.04
mmol/l
1.92
71
1269
17
580
0.26
8.01
2.1
2.7
—
—
—
0
0
80
1336
0.50
7.56
3.4
3.7
15.30
15.44
pmol/l
0.21
64
1129
12
457
0.24
6.76
2.3
2.5
23.00
18.51
%
—
7
411
66
1138
0.49
6.73
3.2
4.3
31.87
32.63
g/l
0.35
51
1017
16
491
0.29
6.18
1.9
2.4
2.23
2.20
g/l
—
9
440
41
815
0.44
6.16
2.2
2.4
2.78
3.38
mg/l
1.41
30
662
21
557
0.34
6.12
2.1
2.8
390.62
397.07
umol/l
0.08
13
449
104
1524
0.57
6.03
18.3
25.9
14.31
14.45
%
0.52
94
1483
15
448
0.30
5.50
2.5
3.0
2.06
1.18
e6/l
—
10
246
55
932
0.52
5.14
2.9
2.6
53.89
68.16
u/l
0.52
44
811
26
579
0.40
5.13
4.1
4.2
170.40
240.20
ng/l
0.25
21
533
40
753
0.47
5.12
3.2
6.3
27.30
7.13
ug/l
0.46
35
645
44
786
0.50
4.81
2.6
3.4
2.37
2.35
mmol/l
0.50
31
681
12
363
0.30
4.51
2.0
4.6
100.83
104.10
mmol/l
1.35
12
363
41
734
0.50
4.50
3.6
3.5
0.78
0.63
e6/l
0.22
33
549
114
1529
0.64
4.25
17.6
26.9
328.68
327.93
g/l
0.37
105
1489
27
546
0.45
4.17
3.3
3.3
2.50
2.49
mmol/l
0.18
17
461
171
2106
0.68
4.17
20.3
29.9
123.33
124.60
g/l
0.47
152
2035
171
2105
0.68
4.15
19.9
29.7
4.08
4.16
e12/l
0.98
150
1992
171
2105
0.68
4.15
19.9
29.6
92.32
91.97
fl
0.30
152
2031
171
2105
0.68
4.15
19.8
29.7
239.07
234.34
e9/l
0.35
149
2007
171
2105
0.68
4.15
20.1
30.0
36.65
36.90
%
0.15
151
2030
171
2096
0.68
4.01
16.8
25.1
140.08
138.98
mmol/l
2.82
151
2005
171
2096
0.68
4.01
16.9
25.4
4.05
4.05
mmol/l
0.09
151
2005
22
467
0.43
3.85
1.3
1.6
1.07
2.06
mg/l
2.61
17
365
8
247
0.30
3.82
1.5
4.0
1.64
1.44
mmol/l
—
8
239
173
2101
0.69
3.79
17.5
27.5
90.72
95.13
umol/l
1.00
152
2015
20
438
0.42
3.79
2.9
3.1
2.97
2.15
e6/l
0.38
15
240
12
330
0.34
3.77
1.6
4.2
4.17
1.04
mmol/l
—
6
257
33
599
0.50
3.75
2.7
5.4
24.76
23.18
%
0.19
20
339
39
666
0.53
3.66
1.8
2.0
—
—
—
0
0
61
913
0.60
3.55
3.5
3.5
—
—
—
0
0
0
82
0.00
3.35
0.0
2.0
—
0.26
—
0
70
168
2012
0.71
3.22
15.5
20.0
40.28
33.16
mg/l
0.94
138
1749
0
79
0.00
3.17
0.0
2.0
—
0.00
—
0
69
0
81
0.00
3.15
0.0
2.0
—
0.00
—
0
69
11
285
0.36
3.08
1.9
1.8
30.71
30.39
s
0.10
11
273
8
211
0.36
2.87
1.9
1.6
—
—
—
0
0
43
663
0.59
2.79
3.0
2.2
50.87
67.91
u/l
1.03
38
605
32
521
0.57
2.55
1.8
1.8
—
—
—
0
0
86
1106
0.70
2.37
4.8
4.3
0.00
0.01
estimate
0.50
18
271
89
1093
0.74
1.82
4.7
4.3
0.00
4.58
estimate
0.50
20
286
87
1072
0.74
1.81
4.8
4.3
0.00
0.00
estimate
-0.00
18
264
38
527
0.67
1.58
1.9
1.8
435.83
14005357.02
pmol/l
0.50
23
407
7
152
0.44
1.58
1.1
1.4
—
—
—
0
0
11
210
0.49
1.53
3.5
2.3
0.14
0.59
e6/l
1.87
11
205
25
370
0.63
1.42
1.8
1.7
—
—
—
0
0
0
38
0.00
1.34
0.0
1.2
—
—
—
0
0
5
18
2.69
1.23
1.8
1.3
—
—
—
0
0
43
551
0.73
1.18
2.1
1.7
347.84
186.53
u/l
0.84
31
506
0
32
0.00
1.17
0.0
1.1
—
—
—
0
0
0
32
0.00
1.17
0.0
1.3
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
—
—
0
0
13
214
0.58
1.16
1.2
3.2
104.60
112.59
ng/l
—
5
168
0
34
0.00
1.15
0.0
1.3
—
363.41
—
0
34
0
34
0.00
1.15
0.0
1.1
—
1.57
—
0
8
0
35
0.00
1.14
0.0
3.8
—
—
—
0
0
0
35
0.00
1.14
0.0
1.2
—
—
—
0
0
5
22
2.20
0.99
1.8
1.4
—
—
—
0
0
0
28
0.00
0.98
0.0
1.2
—
—
—
0
0
0
28
0.00
0.98
0.0
1.2
—
—
—
0
0
0
28
0.00
0.98
0.0
1.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
0
31
0.00
0.95
0.0
1.6
—
—
—
0
0
26
346
0.71
0.92
1.8
1.7
—
—
—
0
0
89
1006
0.82
0.92
3.9
4.5
51.20
91.81
ng/l
1.47
61
822
11
174
0.60
0.88
1.5
2.2
1.76
1.11
%
0.51
11
169
17
239
0.68
0.82
2.1
2.5
15.03
4.93
ug/l
—
10
199
0
25
0.00
0.79
0.0
1.7
—
755.24
—
0
25
6
32
1.82
0.78
1.7
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
1.6
—
—
—
0
0
0
27
0.00
0.76
0.0
1.6
—
—
—
0
0
50
581
0.81
0.69
2.1
1.8
1353.63
1096.56
nmol/l
0.78
30
417
5
26
1.86
0.68
1.8
1.2
—
—
—
0
0
8
49
1.58
0.61
1.4
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
6
35
1.66
0.56
2.2
2.9
11.57
16.41
pmol/l
—
6
35
6
90
0.64
0.42
1.0
1.2
—
—
—
0
0
6
90
0.64
0.42
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
1.00
—
0
9
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.39
0.0
1.0
—
—
—
0
0
0
18
0.00
0.39
0.0
1.9
—
114.72
—
0
18
0
18
0.00
0.39
0.0
5.0
—
—
—
0
0
0
18
0.00
0.39
0.0
1.0
—
—
—
0
0
6
41
1.42
0.35
1.7
1.3
10719.67
15578.55
e6/l
—
6
31
0
10
0.00
0.21
0.0
1.8
—
78.10
—
0
10
0
10
0.00
0.21
0.0
1.1
—
48.00
—
0
10
0
10
0.00
0.21
0.0
3.5
—
0.50
—
0
10
0
10
0.00
0.21
0.0
1.0
—
4.49
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
10.87
—
0
10
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.20
0.0
1.4
—
—
—
0
0
6
46
1.26
0.20
1.7
1.2
—
—
—
0
0
26
281
0.89
0.20
11.4
8.7
—
—
—
0
0
79
807
0.93
0.20
4.9
4.7
0.00
0.07
estimate
1.96
14
215
6
49
1.18
0.19
1.7
1.2
—
—
—
0
0
29
251
1.12
0.19
5.4
3.7
—
—
—
0
0
6
53
1.09
0.09
1.5
3.3
15.68
14.82
%
—
6
53
57
571
0.96
0.08
4.3
4.4
0.00
0.03
estimate
0.88
15
186
9
83
1.05
0.07
1.7
1.5
—
—
—
0
0
61
605
0.97
0.06
5.0
4.1
0.00
0.01
estimate
0.50
15
207
11
96
1.11
0.05
1.3
1.1
—
—
—
0
0
19
192
0.95
0.03
1.7
1.6
—
—
—
0
0
48
468
0.99
0.00
4.5
4.1
1.02
1.02
kg/l
0.24
31
312
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
3.03
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
133.53
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.42
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.17
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
234.56
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: AD_U_EXMORE – Alzheimer’s disease (undefined), excluding more controls
GWS hits: 3
This endpoint is excluded (different definition than used in FinnGen).