Dengue, including avohilmo

AB1_DENGUE_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A97
  • Hospital discharge: ICD-10 A97
  • Cause of death: ICD-10 A97

3 out of 7 registries used, show all original rules.

82

4. Check minimum number of events

None

82

5. Include endpoints

None

82

6. Filter based on genotype QC (FinnGen only)

71

Control definitions (FinnGen only)

Control exclude
AB1_ARTHROPOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 71 35 36
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 69.82 69.19 70.44

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
75
Matched controls
750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A97
ICD-10 Finland
Dengue
+∞
87.5
66
*
A97
ICPC
No disease
11.3
25.3
50
113
Z2221
NOMESCO Finland
Medical doctor
11.1
23.2
55
149
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
67.0
18.0
20
*
SPAT1336
SPAT
Request for examination
22.7
17.9
26
17
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
13.6
14.5
26
28
WZA30, ,
SPAT
70.3
11.0
12
*
S29
ICPC
Skin symptom/complaint other
5.0
10.6
35
112
EB1SA, ,
SPAT
13.5
10.5
18
17
ZXD10
NOMESCO Finland
Scheduled procedure
5.0
10.3
51
223
L28
ICPC
Limited function/disability (L)
4.8
9.8
32
101
ZXE00
NOMESCO Finland
One hour or less
4.8
9.7
52
239
Z3231
NOMESCO Finland
Registered nurse
4.4
9.3
40
155
A62
ICPC
General and Unspecified, Administrative procedure
28.1
9.2
12
5
A60
ICPC
General and Unspecified, Result test/procedure
14.1
9.1
15
13
T45
ICPC
Metabolic, Observ/health educat/advice/diet
23.4
8.8
12
6
A97.9
ICD-10 Finland
Dengue, unspecified
+∞
8.5
8
*
EB1AA, ,
SPAT
9.6
8.5
17
22
WX402
NOMESCO Finland
General anaesthesia
4.3
8.4
30
100
UJF32, ,
SPAT
18.1
7.5
11
7
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.4
7.4
23
68
R4110
NOMESCO Finland
Physiotherapy
3.8
7.4
39
168
N43
ICPC
Neurological, Other diagnostic procedure
+∞
7.4
7
*
B60
ICPC
Blood and Immunity, Result test/procedure
33.6
7.3
9
*
L17
ICPC
Foot/toe symptom/complaint
3.7
7.2
40
178
WX110, ,
SPAT
8.2
6.9
15
22
T60
ICPC
Metabolic, Result test/procedure
44.1
6.9
8
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.7
6.7
18
47
D19
ICPC
Teeth/gum symptom/complaint
3.5
6.6
34
143
D62
ICPC
Digestive, Administrative procedure
76.0
6.5
7
*
K48
ICPC
Cardiovascular, Clarification/discussion RFE/demand
76.0
6.5
7
*
QBE99, ,
SPAT
29.4
6.4
8
*
H51
ICPC
Ear, I&d/flush/aspiration
29.4
6.4
8
*
M54
ICD-10 Finland
Dorsalgia
4.1
6.1
20
61
SPAT1263
SPAT
Sampling
0.2
6.0
5
235

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
510
+∞
11.55
33.3
21.4
13.62
13.75
%
0.35
75
502
50
212
5.08
10.62
5.7
2.9
0.72
0.39
e6/l
0.43
18
150
22
58
4.95
8.24
19.1
11.5
—
—
—
0
0
50
245
4.12
8.00
5.7
3.2
19.27
292.76
e6/l
0.51
18
184
53
275
4.16
7.70
8.5
3.9
95.37
107.44
e6/l
0.05
19
189
10
5
22.70
7.35
2.0
1.8
9.20
13.08
%
—
10
5
20
57
4.42
6.71
12.2
8.8
24.90
25.17
mmol/l
0.11
20
57
42
200
3.50
6.67
4.9
3.6
7.40
7.40
ph
—
6
140
26
92
3.80
6.49
13.6
8.8
104.19
104.27
mmol/l
0.04
26
92
39
188
3.24
5.90
4.6
3.4
—
0.40
—
0
5
50
289
3.19
5.37
2.4
2.1
95.14
96.73
pmol/l
0.09
28
164
50
291
3.15
5.27
6.1
4.4
36.66
35.45
g/l
0.81
50
278
75
630
+∞
5.13
29.0
20.4
139.33
139.65
mmol/l
0.45
75
616
15
43
4.11
4.91
13.7
3.3
24.00
25.01
mmol/l
0.62
15
43
10
14
8.05
4.83
9.1
1.9
55.80
61.02
%
—
10
14
63
438
3.74
4.58
2.9
4.4
—
—
—
0
0
21
84
3.08
4.16
1.4
1.3
—
—
—
0
0
43
257
2.58
3.90
2.3
2.1
—
—
—
0
0
75
659
+∞
3.82
28.4
21.9
77.53
78.86
umol/l
0.15
75
648
70
575
4.26
3.44
4.9
5.1
2.07
1.86
mu/l
0.63
70
513
7
11
6.88
3.26
1.0
1.2
—
—
—
0
0
31
171
2.39
3.20
2.5
2.2
2.09
3.00
mg/l
1.51
24
154
38
232
2.29
3.08
9.9
5.2
—
—
—
0
0
26
139
2.33
2.83
3.7
3.4
2.46
2.46
mmol/l
0.10
26
119
45
306
2.18
2.69
4.4
3.0
68.76
109.83
ug/l
3.00
45
284
75
684
+∞
2.56
35.1
25.2
30.20
30.28
pg
0.16
75
673
75
684
+∞
2.56
35.4
25.4
132.40
134.50
g/l
0.57
75
673
75
684
+∞
2.56
35.1
25.3
235.39
244.41
e9/l
0.53
66
671
75
684
+∞
2.56
35.1
25.3
6.89
6.70
e9/l
0.33
64
665
75
684
+∞
2.56
37.5
25.9
39.94
40.21
%
0.21
75
673
75
684
+∞
2.56
35.1
25.2
90.77
91.03
fl
0.21
75
673
75
684
+∞
2.56
35.0
25.2
4.49
4.48
e12/l
0.03
64
664
35
222
2.08
2.45
3.8
2.5
—
—
—
0
0
15
66
2.59
2.43
13.7
4.3
5.42
5.96
kpa
1.22
15
66
10
34
3.23
2.39
9.1
2.9
0.49
0.63
%
—
10
34
10
35
3.14
2.31
9.1
2.9
1.56
1.40
%
—
10
35
43
301
2.00
2.23
4.6
3.5
5.95
6.19
ph
0.49
11
166
46
330
2.02
2.23
9.0
5.3
59.04
59.08
%
0.01
46
311
17
83
2.36
2.22
1.6
1.2
—
—
—
0
0
6
14
4.56
2.19
1.8
1.8
—
—
—
0
0
22
122
2.14
2.14
3.3
2.3
2.35
2.33
g/l
0.04
22
109
42
295
1.96
2.13
11.6
11.8
0.00
0.00
e9/l
-0.00
15
227
14
64
2.46
2.10
1.4
1.4
—
—
—
0
0
6
15
4.25
2.08
1.5
1.3
—
—
—
0
0
51
386
2.00
2.05
15.7
9.0
3.90
4.24
e9/l
0.35
28
335
21
118
2.08
1.96
3.5
2.4
19.94
21.61
%
0.25
21
113
13
60
2.41
1.91
1.2
1.2
—
—
—
0
0
58
466
2.08
1.88
3.7
4.1
14.77
14.73
pmol/l
0.05
58
418
5
12
4.38
1.85
1.4
1.4
—
—
—
0
0
22
129
2.00
1.83
3.5
2.4
11.32
12.55
umol/l
0.40
22
120
47
354
1.88
1.83
8.9
5.7
1.83
1.74
e9/l
0.28
23
317
9
36
2.70
1.81
1.0
1.2
—
—
—
0
0
46
349
1.82
1.70
9.0
5.5
0.61
0.59
e9/l
0.10
22
300
60
497
2.04
1.66
10.2
8.3
74.60
80.15
u/l
0.91
60
467
46
351
1.80
1.65
9.0
5.5
0.03
0.04
e9/l
1.04
22
299
6
137
0.39
1.61
1.7
1.7
389.17
469.94
pmol/l
—
6
117
27
178
1.81
1.56
1.2
1.6
—
—
—
0
0
12
59
2.23
1.53
12.1
3.2
4.54
4.24
kpa
0.20
12
59
54
439
1.82
1.49
6.9
4.8
—
65.13
—
0
8
13
67
2.14
1.49
1.5
2.3
—
69.02
—
0
58
46
360
1.72
1.43
10.7
5.7
0.16
0.19
e9/l
0.72
23
316
28
193
1.72
1.37
8.0
4.7
—
—
—
0
0
6
24
2.63
1.33
1.2
1.3
1.63
1.62
g/l
—
6
24
6
25
2.52
1.27
1.8
1.4
—
—
—
0
0
6
25
2.52
1.27
1.8
1.4
—
—
—
0
0
6
25
2.52
1.27
1.8
1.4
—
—
—
0
0
6
25
2.52
1.27
1.2
1.3
0.76
0.86
g/l
—
6
25
5
19
2.74
1.23
1.2
2.0
47.80
34.11
nmol/l
—
5
19
5
19
2.74
1.23
1.4
1.3
—
—
—
0
0
6
26
2.42
1.21
1.8
1.4
—
—
—
0
0
6
26
2.42
1.21
1.8
1.4
—
—
—
0
0
18
114
1.76
1.16
2.6
3.1
0.77
0.81
mmol/l
0.88
18
107
7
31
2.38
1.14
4.6
4.4
4.61
4.44
pmol/l
—
7
26
15
229
0.57
1.12
2.3
3.3
—
—
—
0
0
5
21
2.48
1.11
2.0
1.4
—
—
—
0
0
37
287
1.57
1.09
4.1
2.8
—
—
estimate
—
0
0
15
92
1.79
1.07
1.1
1.4
—
—
—
0
0
10
53
2.02
1.07
1.8
1.8
—
—
—
0
0
0
29
0.00
1.00
0.0
4.8
—
36.98
—
0
29
0
31
0.00
0.99
0.0
3.2
—
208.21
—
0
14
0
32
0.00
0.97
0.0
4.5
—
24.74
—
0
32
0
24
0.00
0.81
0.0
1.3
—
—
—
0
0
11
67
1.75
0.80
1.4
1.4
—
—
—
0
0
0
26
0.00
0.80
0.0
2.3
—
24.60
—
0
26
0
26
0.00
0.80
0.0
3.2
—
7.43
—
0
26
46
392
1.45
0.77
10.9
5.6
6.88
6.83
mmol/l
0.06
46
369
63
572
1.63
0.77
4.7
7.0
39.44
39.87
mmol/mol
0.13
63
529
11
68
1.72
0.76
2.8
2.5
0.24
0.20
g/l
0.81
11
62
9
58
1.63
0.73
1.3
1.3
—
—
—
0
0
10
61
1.74
0.72
3.6
2.5
65.75
66.52
g/l
—
10
53
13
87
1.60
0.69
2.2
1.7
—
—
—
0
0
37
309
1.39
0.67
17.6
15.8
1.20
1.28
inr
0.43
28
255
13
89
1.56
0.63
2.6
2.1
1.72
1.80
%
0.15
13
79
18
133
1.46
0.62
2.6
2.1
—
—
—
0
0
0
20
0.00
0.61
0.0
2.4
—
2.72
—
0
13
0
20
0.00
0.61
0.0
2.4
—
9.13
—
0
20
0
20
0.00
0.61
0.0
5.5
—
—
—
0
0
0
20
0.00
0.61
0.0
2.4
—
4.87
—
0
20
0
21
0.00
0.61
0.0
4.2
—
1.68
—
0
21
15
201
0.68
0.59
2.7
2.5
58.60
54.25
u/l
0.26
15
186
6
39
1.58
0.54
1.5
1.1
—
158.41
—
0
16
15
110
1.45
0.54
3.9
1.9
—
—
—
0
0
5
80
0.60
0.49
1.4
3.3
3.95
4.86
e9/l
—
5
64
10
69
1.52
0.47
1.2
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
15.82
—
0
15
0
16
0.00
0.41
0.0
4.8
—
8.23
—
0
16
0
17
0.00
0.41
0.0
2.4
—
91.18
—
0
17
0
18
0.00
0.40
0.0
10.3
—
—
—
0
0
0
18
0.00
0.40
0.0
2.8
—
—
—
0
0
0
18
0.00
0.40
0.0
3.9
—
37.95
—
0
11
7
97
0.69
0.33
1.4
1.3
—
427.20
—
0
25
14
115
1.27
0.26
1.9
1.7
—
—
—
0
0
6
84
0.69
0.25
2.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
90.62
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
4.0
—
19.27
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
4.3
—
105.90
—
0
10
0
10
0.00
0.21
0.0
4.3
—
4.07
—
0
10
0
10
0.00
0.21
0.0
4.3
—
1.21
—
0
10
0
10
0.00
0.21
0.0
1.0
—
32.30
—
0
10
47
442
1.17
0.21
5.4
4.6
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
1.71
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
0.91
—
0
7
0
12
0.00
0.21
0.0
3.0
—
—
—
0
0
0
13
0.00
0.21
0.0
5.0
—
31.15
—
0
13
0
13
0.00
0.21
0.0
3.0
—
—
—
0
0
6
48
1.27
0.21
1.2
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
4.9
—
14.79
—
0
14
7
57
1.25
0.19
6.7
3.2
84.00
76.15
ng/l
—
7
49
17
149
1.18
0.17
1.9
1.3
1.50
2.74
g/l
—
8
80
9
81
1.13
0.16
4.6
1.8
—
—
—
0
0
10
116
0.84
0.13
1.3
1.3
—
9.12
—
0
40
20
218
0.89
0.12
3.5
3.2
11.01
8.06
mmol/l
1.60
20
179
5
48
1.04
0.09
2.8
1.7
1.15
1.11
g/l
—
5
43
6
56
1.08
0.09
4.8
2.5
—
—
—
0
0
20
210
0.94
0.04
5.1
3.0
—
—
—
0
0
20
210
0.94
0.04
14.1
5.8
—
—
—
0
0
14
148
0.93
0.02
2.3
4.7
—
—
—
0
0
21
202
1.06
0.02
1.6
2.1
181.62
192.43
u/l
0.06
21
192
64
643
0.97
0.00
8.6
15.6
—
—
—
0
0
18
177
1.02
0.00
3.7
2.6
310.28
345.81
umol/l
0.49
18
149
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
31.42
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
40.56
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.8
2.2
3.22
3.43
mmol/l
—
5
39
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
9.32
—
0
9
0
9
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_DENGUE_WIDE – Dengue, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).