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Androgenic alopecia

DOID EFO Endpoint Browser PheWeb

L12_ALOPECANDRO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L64
  • Hospital discharge: ICD-9 — 7040A
  • Cause of death: ICD-10 — L64
  • Cause of death: ICD-9 — 7040A

2 out of 7 registries used, show all original rules.

381

4. Check minimum number of events

None

381

5. Include endpoints

None

381

6. Filter based on genotype QC (FinnGen only)

345

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alopecia androgenica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1684 1684 -
Only index persons 1625 1625 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 43.96 -
Only index persons - 43.20 -

-FinnGen-

Key figures

All Female Male
Number of individuals 345 345 -
Unadjusted period prevalence (%) 0.12 0.12 -
Median age at first event (years) 51.76 51.76 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
362
Matched controls
3620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L64.9
ICD-10 Finland
Androgenic alopecia, unspecified
5450.0
251.9
213
*
L64.8
ICD-10 Finland
Other androgenic alopecia
+∞
152.1
135
*
C03DA01
ATC
spironolactone; oral
12.7
114.8
140
171
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
124.7
32.3
34
*
L63.9
ICD-10 Finland
Alopecia areata, unspecified
163.0
29.1
30
*
L64
ICD-10 Finland
Androgenic alopecia
163.0
29.1
30
*
D07AC01
ATC
betamethasone; topical
3.3
28.1
199
971
L63.8
ICD-10 Finland
Other alopecia areata
267.7
25.0
25
*
S23
ICPC
Hair loss/baldness
23.2
19.8
28
13
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.6
18.9
74
244
D07AC13
ATC
mometasone; topical
2.7
17.9
152
772
L65.8
ICD-10 Finland
Other specified nonscarring hair loss
188.9
17.7
18
*
D07AD01
ATC
clobetasol; topical
2.9
17.2
101
423
G04CB01
ATC
finasteride; oral
+∞
16.8
16
*
L64.0
ICD-10 Finland
Drug-induced androgenic alopecia
+∞
14.7
14
*
L63.0
ICD-10 Finland
Alopecia (capitis) totalis
+∞
14.7
14
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.6
14.5
114
548
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
13.7
48
146
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
11.7
199
1305
XQ802
NOMESCO Finland
Epicutan test
3.8
11.6
37
105
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
11.2
144
843
L68.0
ICD-10 Finland
Hirsutism
61.9
10.7
12
*
N06AB05
ATC
paroxetine; oral
3.5
10.4
37
113
E0000UV, ,
ATC
2.0
10.1
184
1216
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
9.8
123
707
H03AA01
ATC
levothyroxine sodium; systemic
2.1
9.5
124
721
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
9.4
169
1103
L70.0
ICD-10 Finland
Acne vulgaris
12.0
8.6
15
13
L71.8
ICD-10 Finland
Other rosacea
16.8
8.6
13
8
L60.0
ICD-10 Finland
Ingrowing nail
3.9
8.5
25
67
J01AA04
ATC
lymecycline; systemic
2.4
8.4
61
277
G03HB01
ATC
cyproterone and estrogen; oral
2.4
8.3
67
319
L72.1
ICD-10 Finland
Trichilemmal cyst
3.5
8.3
29
88
L21.0
ICD-10 Finland
Seborrhoea capitis
10.4
8.1
15
15
N06AX21
ATC
duloxetine; oral
2.3
7.9
69
340
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
7.8
68
335
D10BA01
ATC
isotretinoin; oral
3.1
7.8
33
113
G03HA01
ATC
cyproterone; systemic
81.7
7.4
8
*
B07.9
ICD-10 Finland
Verruca simplex
3.8
7.4
23
64
L82
ICD-10 Finland
Seborrhoeic keratosis
2.1
7.4
87
482
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
7.1
94
541
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.6
6.9
43
181
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
6.9
93
540
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.5
6.9
46
201
XQ845
NOMESCO Finland
Dermatoscopy
7.4
6.8
15
21
N06AX26
ATC
vortioxetine; oral
2.6
6.6
40
166
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.3
143
974
L66.1
ICD-10 Finland
Lichen planopilaris
+∞
6.3
6
*
L65.0
ICD-10 Finland
Telogen effluvium
27.2
6.3
8
*
L71.9
ICD-10 Finland
Rosacea, unspecified
5.7
6.1
16
29
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.9
6.0
89
530

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
152
3.74
15.01
1.4
1.2
0.28
1.09
u/ml
—
6
10
25
26
10.24
12.94
1.2
1.1
21.55
28.77
umol/l
0.38
25
21
163
970
2.24
12.44
1.5
1.3
0.82
2.41
u/ml
1.40
50
259
252
1831
2.24
11.16
3.9
3.1
75.85
78.47
ug/l
0.18
244
1722
101
535
2.23
9.87
1.4
1.4
629.47
573.44
titre
0.07
19
122
38
135
3.03
8.41
1.2
1.3
—
—
—
0
0
72
355
2.28
8.24
2.4
2.0
416.61
374.62
nmol/l
0.73
67
339
330
2828
2.89
8.10
7.3
4.8
14.90
14.58
pmol/l
1.72
313
2635
222
1644
1.91
8.00
2.8
2.5
81.75
78.73
nmol/l
0.93
211
1503
47
196
2.61
7.72
1.2
1.1
—
195.71
—
0
7
191
1358
1.86
7.71
5.2
4.2
36.86
36.47
g/l
0.48
183
1284
48
213
2.45
6.92
4.6
3.3
—
—
—
0
0
213
1601
1.80
6.86
7.2
6.0
1.21
1.22
mmol/l
1.33
193
1368
63
321
2.17
6.59
1.4
1.3
157.13
173.65
u/ml
0.10
31
137
197
1458
1.77
6.58
2.3
2.0
—
—
—
0
0
141
951
1.79
6.46
2.5
2.0
146.16
144.61
u/l
0.02
135
904
146
1003
1.76
6.23
3.3
2.3
60.49
63.84
u/l
0.20
138
928
128
847
1.79
6.20
2.5
2.1
2.70
2.82
mg/l
0.19
117
726
294
2486
1.97
6.01
8.0
7.4
75.57
76.53
u/l
0.17
282
2344
86
508
1.91
5.96
1.8
2.1
132.07
89.17
ug/g
0.48
70
399
36
150
2.55
5.92
2.4
2.3
—
—
—
0
0
190
1420
1.71
5.90
2.4
2.0
98.77
99.26
pmol/l
0.05
102
698
221
1725
1.72
5.81
5.6
5.8
0.04
0.04
e9/l
0.15
199
1471
227
1785
1.73
5.81
5.8
6.1
0.18
0.18
e9/l
0.07
210
1550
32
127
2.67
5.80
1.4
1.2
33.64
13.87
u/ml
—
7
23
219
1714
1.70
5.62
5.6
5.8
0.51
0.53
e9/l
1.09
198
1463
239
1916
1.73
5.61
7.6
8.8
3.95
3.90
e9/l
0.11
212
1668
133
911
1.73
5.61
1.7
1.6
20.44
21.56
nmol/l
0.48
122
778
223
1758
1.70
5.53
6.0
5.8
1.92
1.99
e9/l
0.43
207
1545
119
793
1.75
5.52
1.4
1.3
32.44
32.72
iu/ml
0.01
28
249
81
483
1.87
5.42
3.1
2.5
0.87
0.82
mmol/l
1.41
75
456
120
806
1.73
5.39
1.8
1.6
0.83
0.98
mg/l
0.30
89
627
55
289
2.06
5.29
2.3
2.9
23.83
76.04
u/ml
0.69
49
277
54
282
2.08
5.28
1.4
1.3
20.23
25.28
iu/l
0.59
45
243
99
638
1.76
5.11
2.0
1.6
458.69
22905476.63
pmol/l
0.78
87
537
54
286
2.04
5.08
1.3
1.2
147.06
200.45
u/ml
0.25
49
263
77
461
1.85
5.06
1.3
1.2
—
—
—
0
0
172
1287
1.64
5.06
14.0
8.9
1.16
1.13
inr
0.35
137
1035
192
1480
1.63
4.99
4.9
3.3
6.36
6.22
ph
1.00
111
823
63
355
1.94
4.98
2.3
2.3
4.40
5.17
umol/l
0.68
51
306
152
1111
1.63
4.86
3.6
3.2
11.69
26.70
ng/l
1.94
91
666
69
404
1.87
4.86
1.6
1.3
—
—
—
0
0
59
328
1.95
4.85
1.1
1.2
—
—
—
0
0
13
25
5.35
4.81
1.0
1.1
133.46
107.56
pmol/l
2.08
13
25
215
1714
1.63
4.80
5.6
5.6
9.37
9.68
umol/l
0.25
205
1619
159
1183
1.61
4.68
3.0
3.2
2.35
2.36
mmol/l
0.80
146
1081
149
1095
1.61
4.60
3.1
2.8
—
—
—
0
0
99
657
1.70
4.54
2.4
2.5
2.43
2.45
mmol/l
1.14
90
597
61
351
1.89
4.52
9.8
5.7
105.23
104.38
mmol/l
0.79
61
351
59
336
1.90
4.51
2.1
1.5
—
—
—
0
0
117
813
1.65
4.50
1.5
1.4
2.03
2.20
g/l
0.43
74
487
50
269
2.00
4.50
1.3
1.3
—
—
—
0
0
224
1823
1.60
4.43
6.2
4.2
6.39
6.45
mmol/l
0.21
215
1690
332
3015
2.22
4.38
7.6
5.7
38.81
38.14
mmol/mol
0.82
318
2849
76
478
1.75
4.21
2.5
2.3
12.96
13.81
umol/l
0.56
70
448
59
344
1.85
4.19
4.0
4.3
1.07
1.04
mmol/l
0.32
54
310
182
1430
1.55
4.06
6.7
5.2
1.21
1.22
mmol/l
1.59
172
1314
354
3360
3.42
4.02
16.4
11.8
—
—
—
0
0
46
251
1.95
3.98
3.2
3.0
7.38
7.38
ph
0.02
26
138
260
2230
1.59
3.79
6.2
4.5
—
2857.22
—
0
27
134
997
1.55
3.75
3.1
3.0
20.42
39.14
e6/l
1.13
111
738
112
801
1.58
3.73
5.4
3.6
1.02
1.02
kg/l
0.47
67
522
343
3190
2.43
3.69
9.1
5.9
1.70
1.81
mu/l
1.45
333
3004
174
1375
1.51
3.66
5.7
3.5
0.03
0.02
estimate
0.15
36
302
339
3144
2.23
3.56
6.1
4.8
5.84
5.76
mmol/l
0.58
324
2930
43
240
1.90
3.49
3.2
2.9
1.49
2.03
mmol/l
0.44
37
207
32
162
2.07
3.41
2.3
2.0
6.59
6.25
iu/ml
—
7
35
22
96
2.38
3.34
1.6
1.3
—
—
—
0
0
116
860
1.51
3.22
3.0
2.9
0.20
0.42
e6/l
1.85
93
602
219
1847
1.47
3.15
5.6
3.7
0.00
7.92
estimate
0.80
44
383
12
35
3.51
3.13
2.1
1.5
23.27
23.70
ng/l
0.03
12
35
111
822
1.51
3.08
5.4
3.6
—
0.00
—
0
5
219
1854
1.46
3.04
5.6
3.8
0.00
0.02
estimate
0.80
44
367
16
63
2.61
3.00
1.1
1.1
71.66
13.46
au/ml
—
5
21
101
739
1.51
2.95
1.4
1.3
2.96
9.42
u/ml
2.23
52
293
215
1824
1.44
2.88
5.6
3.7
0.00
0.00
estimate
0.50
42
379
7
13
5.47
2.88
1.1
1.3
104.14
154.69
nmol/l
—
7
13
344
3247
2.20
2.80
16.5
12.8
19.60
20.14
mg/l
0.12
287
2591
27
139
2.02
2.78
4.5
4.8
—
—
—
0
0
110
833
1.46
2.69
5.0
4.4
—
—
—
0
0
151
1213
1.42
2.68
4.0
3.7
48.36
80.01
e6/l
0.47
118
791
14
55
2.61
2.64
1.2
1.3
—
—
—
0
0
30
164
1.90
2.62
13.8
8.0
0.79
0.63
%
1.88
30
164
12
42
2.92
2.57
1.3
1.3
287.75
427.49
pmol/l
0.64
12
35
57
378
1.60
2.56
1.2
1.3
—
—
—
0
0
34
198
1.79
2.46
1.6
1.2
—
—
—
0
0
256
2275
1.43
2.44
3.8
3.1
36.16
39.01
u/l
0.39
250
2160
23
118
2.01
2.41
5.3
4.0
1.61
1.58
%
0.06
23
113
141
1137
1.39
2.39
3.0
3.0
81.38
27.28
u/l
0.85
136
1081
30
170
1.83
2.37
13.7
7.9
1.43
1.19
%
1.26
30
170
40
248
1.69
2.34
2.8
3.4
78.83
74.67
ng/l
0.08
35
221
18
86
2.15
2.27
1.8
1.5
29.51
25.35
u/l
0.22
18
74
20
102
2.02
2.15
1.5
2.4
1.47
1.33
g/l
0.26
15
89
130
1050
1.37
2.14
3.5
3.1
6.81
7.08
mmol/l
0.32
117
884
64
455
1.49
2.12
2.3
2.3
2.44
2.40
g/l
0.19
58
421
188
1612
1.35
2.09
5.8
5.9
29.07
29.29
%
0.11
178
1518
179
1524
1.35
2.08
9.6
9.7
0.00
0.00
e9/l
0.42
145
1240
12
50
2.45
2.04
1.9
2.7
13.25
13.27
%
0.02
12
50
184
1578
1.34
2.02
5.5
6.0
8.09
8.47
%
1.35
172
1467
15
70
2.19
2.01
1.9
2.0
8.79
6.53
pmol/l
0.36
15
70
74
548
1.44
2.00
3.2
3.4
183.73
352.46
ng/l
0.40
48
372
78
584
1.43
1.99
3.2
2.6
493.32
496.26
mosm/kgh2o
0.04
71
504
9
33
2.77
1.94
1.3
1.0
—
—
—
0
0
16
78
2.10
1.94
1.1
1.0
1.25
1.87
u/ml
—
9
34
13
58
2.29
1.93
3.6
2.6
3.93
4.47
e9/l
0.44
13
58
13
58
2.29
1.93
5.6
3.8
—
—
—
0
0
44
296
1.55
1.89
12.1
6.8
0.24
0.97
mmol/l
0.41
37
246
20
108
1.90
1.85
6.0
4.3
0.89
0.88
%
0.03
20
103
118
957
1.35
1.85
3.6
3.2
13.18
38.08
mg/l
3.51
77
554
183
1588
1.31
1.77
5.7
5.8
57.17
56.55
%
0.33
174
1508
44
301
1.53
1.76
12.2
6.7
4.97
5.17
kpa
1.14
44
294
44
301
1.53
1.76
12.2
6.7
13.38
13.07
kpa
0.12
44
294
182
1581
1.30
1.73
5.5
5.9
2.89
2.81
%
0.20
170
1466
67
502
1.41
1.70
1.8
1.8
—
—
—
0
0
182
1584
1.30
1.70
5.6
5.9
0.70
0.72
%
0.26
170
1464
22
127
1.78
1.68
1.1
1.4
0.24
0.27
mg/l
—
8
48
321
3037
1.50
1.68
4.7
4.0
1.33
1.21
mmol/l
2.65
304
2817
14
69
2.07
1.67
2.1
4.3
3.61
3.85
mmol/l
1.38
14
69
10
41
2.48
1.65
1.0
1.0
—
—
—
0
0
131
1095
1.31
1.64
5.4
5.5
—
—
—
0
0
186
1630
1.29
1.62
3.2
2.6
—
—
estimate
—
0
0
43
299
1.50
1.61
12.5
6.8
7.41
7.41
ph
0.06
27
174
8
32
2.53
1.60
1.3
1.5
—
—
—
0
0
118
975
1.31
1.60
4.5
3.9
3.65
8.23
mg/mmol
1.56
76
536
121
1006
1.30
1.56
6.3
3.8
0.00
0.00
estimate
0.50
42
366
5
15
3.36
1.53
2.0
1.1
—
—
—
0
0
6
21
2.89
1.51
1.2
1.2
—
—
—
0
0
118
992
1.28
1.38
3.7
3.5
7.40
7.40
ph
0.02
89
683
25
160
1.60
1.35
3.4
2.5
123.72
129.42
g/l
0.62
25
155
338
3257
1.57
1.33
6.6
5.5
2.79
2.84
mmol/l
0.47
321
3060
16
91
1.79
1.31
1.1
1.1
0.43
2.42
u/ml
—
8
48
53
401
1.38
1.29
1.7
1.5
—
—
—
0
0
5
18
2.80
1.29
5.8
3.0
71.00
101.89
nmol/l
—
5
18
36
254
1.46
1.28
2.5
2.4
15.06
19.55
au/ml
—
5
22
334
3215
1.50
1.26
5.6
4.7
1.52
1.59
mmol/l
2.38
319
3016
8
36
2.25
1.25
1.1
1.1
—
—
—
0
0
55
423
1.35
1.21
1.8
3.2
4.53
5.07
e9/l
0.28
50
376
18
109
1.69
1.21
1.6
1.3
296.45
315.11
ug/g
0.14
11
62
14
79
1.80
1.18
3.7
2.5
56.36
59.14
%
0.45
14
79
17
103
1.68
1.15
1.5
1.2
—
—
—
0
0
13
73
1.81
1.12
1.0
1.0
2.09
1.22
u/ml
—
6
30
125
1083
1.24
1.11
2.4
2.1
—
—
—
0
0
85
705
1.27
1.10
3.0
3.5
—
—
—
0
0
26
178
1.50
1.09
1.3
2.3
—
—
—
0
0
334
3233
1.43
1.02
5.8
4.8
4.77
4.86
mmol/l
1.23
320
3040
59
472
1.30
1.01
1.7
1.6
1286.98
1202.29
nmol/l
0.29
45
349
7
35
2.02
1.00
2.1
1.4
—
—
—
0
0
7
35
2.02
1.00
2.1
1.4
—
—
—
0
0
7
35
2.02
1.00
2.1
1.4
—
—
—
0
0
7
35
2.02
1.00
2.1
1.4
—
—
—
0
0
17
108
1.60
0.98
1.2
1.2
—
—
—
0
0
9
51
1.78
0.95
1.1
1.2
—
—
nmol/l
—
0
0
37
279
1.36
0.95
3.3
4.5
0.20
0.86
%
—
5
70
52
414
1.30
0.93
2.4
1.9
—
—
—
0
0
33
246
1.38
0.91
13.7
5.7
1.50
1.18
mmol/l
0.40
33
241
29
212
1.40
0.89
16.1
7.0
—
—
—
0
0
38
291
1.34
0.89
3.1
3.9
7.32
7.35
ph
0.32
27
203
8
42
1.92
0.89
1.3
1.2
—
—
—
0
0
30
221
1.39
0.89
2.5
2.2
6159.27
7946.65
u/l
0.17
11
105
55
446
1.27
0.86
1.3
1.2
—
—
—
0
0
37
287
1.32
0.81
1.4
1.4
—
—
—
0
0
6
33
1.83
0.79
1.5
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
4.0
—
—
—
0
0
43
343
1.29
0.78
1.9
2.0
0.00
0.07
estimate
—
9
74
6
34
1.78
0.76
1.5
3.5
—
—
—
0
0
115
1023
1.18
0.75
4.8
3.2
0.05
0.01
estimate
0.33
38
305
5
24
2.10
0.75
1.6
1.2
30.12
33.71
nmol/l
—
5
19
5
25
2.01
0.73
1.0
1.2
—
—
—
0
0
162
1489
1.16
0.70
2.0
1.9
1.45
1.33
mmol/l
1.22
145
1289
87
762
1.19
0.68
2.2
2.5
296.85
306.65
umol/l
0.47
80
683
56
471
1.22
0.66
1.6
1.9
—
—
—
0
0
17
122
1.41
0.61
3.0
2.0
3.28
4.74
iu/l
—
10
45
6
37
1.63
0.56
1.2
1.0
—
—
—
0
0
6
37
1.63
0.56
1.5
1.2
—
—
—
0
0
39
323
1.23
0.55
1.5
1.4
—
—
—
0
0
11
74
1.50
0.54
1.0
4.6
28.53
34.97
mg/l
0.31
11
64
11
74
1.50
0.54
1.0
4.6
20.59
27.73
mg/l
0.79
11
62
7
45
1.57
0.49
1.0
1.2
—
—
—
0
0
7
45
1.57
0.49
1.0
1.1
—
—
—
0
0
76
678
1.15
0.48
1.9
1.7
—
—
—
0
0
12
85
1.43
0.47
3.7
1.2
4.11
3.65
mmol/l
0.51
12
79
13
94
1.40
0.46
10.4
6.5
—
—
—
0
0
7
49
1.44
0.46
1.0
1.1
—
—
—
0
0
54
472
1.17
0.45
2.3
2.8
2.33
4.04
e6/l
1.34
31
205
8
56
1.44
0.43
2.9
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
4.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
10
71
1.42
0.39
4.8
1.2
—
—
—
0
0
5
35
1.43
0.39
1.6
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
3.9
—
10.10
—
0
10
14
181
0.76
0.39
2.3
2.1
0.00
0.02
estimate
—
7
59
8
115
0.69
0.37
1.6
3.6
—
—
—
0
0
9
71
1.27
0.36
1.6
1.5
1.25
0.87
nmol/l
—
9
56
6
45
1.34
0.34
1.2
1.1
—
—
—
0
0
36
313
1.17
0.34
2.6
4.1
3.21
9.92
ug/l
2.25
22
248
6
47
1.28
0.32
1.7
2.0
16.07
16.25
%
—
6
47
7
54
1.30
0.30
1.4
1.4
—
—
—
0
0
23
194
1.20
0.30
1.5
2.8
83.26
74.42
e9/l
0.41
18
147
12
93
1.30
0.30
3.8
1.3
534.00
416.17
mg/l
0.34
12
87
19
157
1.22
0.30
1.6
1.3
164.00
266.42
miu/ml
—
10
81
7
57
1.23
0.29
1.7
1.2
—
—
—
0
0
21
177
1.20
0.28
1.3
1.1
—
—
—
0
0
142
1357
1.08
0.26
3.0
2.9
—
—
—
0
0
9
77
1.17
0.24
1.6
1.3
—
—
—
0
0
16
135
1.19
0.22
1.3
1.1
1.55
1.62
g/l
0.68
16
135
5
42
1.19
0.21
6.8
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
5.1
—
1.00
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
17.60
—
0
10
12
145
0.82
0.21
1.9
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
4.5
—
—
—
0
0
105
1001
1.07
0.20
4.8
5.8
—
—
—
0
0
103
1079
0.94
0.20
1.6
1.6
—
—
—
0
0
28
251
1.13
0.19
1.7
1.7
—
—
—
0
0
6
53
1.13
0.19
1.8
2.5
—
—
—
0
0
12
142
0.84
0.18
1.9
1.5
—
—
—
0
0
31
283
1.10
0.16
6.0
3.7
—
—
—
0
0
16
140
1.15
0.15
1.3
1.2
0.86
0.91
g/l
0.38
16
140
30
275
1.10
0.15
3.7
2.4
5.83
6.18
ph
1.65
20
177
7
88
0.79
0.14
1.7
2.5
25.26
25.05
mmol/l
—
7
88
14
159
0.88
0.13
2.5
1.8
—
—
—
0
0
32
344
0.92
0.12
1.3
1.3
—
—
—
0
0
19
172
1.11
0.11
1.2
1.1
—
—
—
0
0
10
86
1.17
0.11
2.9
1.4
702.60
194.26
ug/l
—
10
76
30
319
0.94
0.09
2.0
1.7
3.23
3.40
mmol/l
0.43
22
234
14
154
0.91
0.08
1.7
1.8
—
—
—
0
0
49
471
1.05
0.08
1.6
1.5
—
—
—
0
0
6
75
0.80
0.07
2.0
2.2
—
—
—
0
0
7
80
0.87
0.07
1.3
1.1
—
—
—
0
0
7
80
0.87
0.07
1.3
1.1
—
—
—
0
0
9
87
1.04
0.07
1.2
1.2
—
112.14
—
0
14
9
101
0.89
0.06
1.7
1.8
—
—
—
0
0
28
267
1.05
0.05
1.7
1.3
—
—
—
0
0
10
110
0.91
0.05
1.5
1.3
—
—
—
0
0
11
116
0.95
0.00
1.3
1.3
—
—
—
0
0
13
136
0.95
0.00
1.2
1.3
—
—
—
0
0
10
98
1.02
0.00
2.8
1.6
1.85
3.85
ug/l
—
10
91
10
102
0.98
0.00
1.1
1.5
—
—
—
0
0
10
102
0.98
0.00
1.2
1.1
—
—
—
0
0
14
142
0.99
0.00
1.3
1.3
—
—
—
0
0
14
142
0.99
0.00
1.3
1.3
—
—
—
0
0
14
142
0.99
0.00
1.3
1.3
—
—
—
0
0
14
143
0.98
0.00
1.3
1.3
—
—
—
0
0
78
776
1.01
0.00
2.4
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.74
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
56.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
27.78
—
0
9
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
7.79
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
6.43
—
0
7
0
7
0.00
-0.00
0.0
2.1
—
19.49
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
15
150
1.00
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
57
0.88
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
126.17
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.1
—
0.16
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint L12_ALOPECANDRO and mortality.

Females

Parameter HR [95% CI] p-value
L12_ALOPECANDRO 1.266 [1.01, 1.59] 0.043
Birth year 0.997 [0.99, 1.01] 0.532

During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 1383 females with L12_ALOPECANDRO died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ALOPECANDRO.

N-year risk Females Males
1 0.143% No data
5 0.796% No data
10 1.985% No data
15 3.694% No data
20 6.598% No data

Relationships between endpoints

↥

Index endpoint: L12_ALOPECANDRO – Androgenic alopecia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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