This is a non-core endpoint: only basic statistics are computed.
Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
81 |
4. Check minimum number of eventsNone |
81 |
5. Include endpointsNone |
81 |
6. Filter based on genotype QC (FinnGen only) |
71 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, including Hilmo
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm of eye, brain and central nervous system, including Hilmo
- Solid cancers
- Malignant neoplasm
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 71 | 32 | 39 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 52.18 | 49.93 | 54.02 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 74
- Matched controls
- 740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
36.5
32
*
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
35.2
31
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
27.9
25
*
H02AB02
ATC
dexamethasone; systemic
116.0
23.3
24
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
20.8
19
*
130
Kela drug reimbursment
Malignant tumour
+∞
18.5
17
*
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
18.5
17
*
N03AX16
ATC
[U] pregabalin
7.3
16.5
37
89
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
16.2
15
*
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
+∞
15.1
14
*
N02AA05
ATC
oxycodone; systemic
7.9
13.7
23
40
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
61.7
13.4
15
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
155.2
12.9
13
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
14.7
12.0
20
18
A03FA01
ATC
metoclopramide; systemic, rectal
6.6
11.9
24
50
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
11.8
11
*
D33.43
ICD-10 Finland
Spinal cord
+∞
11.8
11
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
33.9
11.2
14
5
ZXE20
NOMESCO Finland
More than three and less than five hours
6.4
10.8
22
46
M03BX01
ATC
baclofen; systemic
28.2
10.7
14
6
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
10.7
10
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
10.7
10
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
15.3
9.9
16
13
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
25.8
9.7
13
6
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
35.2
9.7
12
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.8
9.7
32
102
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.2
9.3
24
62
L28
ICPC
Limited function/disability (L)
4.8
9.0
27
79
A04AA01
ATC
ondansetron; systemic, rectal
57.0
8.9
10
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
15.3
8.8
14
11
WF002
NOMESCO Finland
Radical radiotherapy
101.1
8.6
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.5
8
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
8.5
8
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
8.5
8
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.6
8.2
18
40
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
9.4
7.9
16
21
XKC03
NOMESCO Finland
Water cystometry
18.1
7.5
11
7
JN4AD
NOMESCO Finland
Body CT examination
10.5
7.4
14
16
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.4
7
*
C72.0
ICD-10 Finland
Malignant neoplasm: Spinal cord
+∞
7.4
7
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
7.4
7
*
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
7.4
7
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
+∞
7.4
7
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
7.4
7
*
R4110
NOMESCO Finland
Physiotherapy
3.9
7.4
31
115
N03AE01
ATC
clonazepam; systemic
9.9
7.2
14
17
Z51.5
ICD-10 Finland
Palliative care
15.9
7.1
11
8
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.9
7.1
16
25
XX3DW
NOMESCO Finland
Time consuming IT work
12.7
7.1
12
11
JN4BD
NOMESCO Finland
Extensive body CT
9.3
7.0
14
18
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
44.2
6.9
8
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.6
6.6
18
48
L03AA13
ATC
pegfilgrastim; parenteral
76.1
6.5
7
*
N18
ICPC
Paralysis/weakness
20.2
6.4
9
5
1922A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Spinal cord
+∞
6.3
6
*
WX402
NOMESCO Finland
General anaesthesia
3.7
6.1
24
84
R4120
NOMESCO Finland
Occupational therapy
8.0
6.1
13
19
UKC02
NOMESCO Finland
Cystoscopy
4.3
6.1
18
51
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
30
9.33
9.94
3.4
10.9
24.98
25.31
mmol/l
0.12
21
30
10
5
22.75
7.35
2.4
2.4
—
—
—
0
0
52
279
3.91
6.97
7.3
6.0
1.19
1.22
mmol/l
1.72
46
242
32
131
3.54
6.43
2.7
1.9
—
—
—
0
0
47
251
3.39
6.05
2.9
2.4
—
—
estimate
—
0
0
16
33
5.89
5.86
4.8
13.9
0.61
0.74
%
0.57
16
33
20
63
3.98
5.84
3.7
9.1
103.50
104.51
mmol/l
0.38
20
63
16
34
5.71
5.73
4.8
13.6
1.20
1.41
%
0.43
16
34
16
34
5.71
5.73
4.8
13.6
94.20
94.17
%
0.01
16
34
7
10
7.59
3.44
1.9
1.1
—
—
—
0
0
7
10
7.59
3.44
1.9
1.1
—
—
—
0
0
20
89
2.71
3.23
3.0
2.4
0.64
4.08
e6/l
0.87
11
29
46
591
0.41
3.13
3.4
4.1
1.20
1.25
mmol/l
0.26
41
546
30
166
2.36
3.06
3.6
2.6
0.54
0.32
e6/l
0.32
25
117
21
99
2.57
3.01
2.7
2.4
0.38
1.19
e6/l
1.23
12
41
19
89
2.53
2.74
2.3
1.6
—
—
—
0
0
44
297
2.19
2.70
8.3
3.5
9.32
11.61
umol/l
2.26
44
278
5
9
5.86
2.25
4.2
1.2
—
—
—
0
0
9
35
2.78
1.87
1.8
3.6
26.22
23.82
mmol/l
—
9
35
13
61
2.37
1.84
2.5
1.6
—
—
—
0
0
6
18
3.53
1.78
1.3
3.2
—
—
—
0
0
7
25
2.98
1.69
1.4
2.8
1.40
1.21
%
—
7
25
5
14
3.75
1.64
3.2
1.4
781.00
407.86
mg/l
—
5
14
8
33
2.59
1.59
2.1
1.5
—
—
—
0
0
0
37
0.00
1.39
0.0
1.5
—
1027.13
—
0
31
8
37
2.30
1.26
1.4
1.2
—
—
—
0
0
17
104
1.82
1.23
4.1
2.0
2.45
2.44
mmol/l
0.26
17
84
12
65
2.01
1.22
2.7
1.5
—
—
—
0
0
0
28
0.00
1.00
0.0
1.5
—
207.60
—
0
15
12
70
1.85
0.99
4.8
4.9
—
—
—
0
0
24
173
1.57
0.95
7.0
3.1
0.00
0.00
estimate
-0.00
11
52
53
456
1.57
0.93
11.3
5.1
75.96
74.86
u/l
0.13
53
424
5
99
0.47
0.85
2.0
1.4
—
—
—
0
0
9
54
1.76
0.78
6.2
2.7
—
—
—
0
0
5
23
2.26
0.78
1.0
1.5
—
—
—
0
0
0
21
0.00
0.61
0.0
1.6
—
0.94
—
0
13
0
21
0.00
0.61
0.0
1.6
—
1.19
—
0
13
0
21
0.00
0.61
0.0
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
1.6
—
1.01
—
0
13
5
89
0.53
0.60
2.0
2.1
3.02
3.26
ratio
—
5
74
36
415
0.74
0.57
3.3
3.2
—
—
—
0
0
67
630
1.67
0.53
25.1
13.9
139.57
139.86
mmol/l
0.45
67
617
11
76
1.53
0.51
1.5
2.6
20.55
25.08
%
0.74
11
68
66
625
1.52
0.41
26.2
11.2
27.89
21.56
mg/l
0.69
61
494
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
67
684
0.78
0.30
36.4
17.6
130.81
137.43
g/l
2.70
67
677
67
684
0.78
0.30
36.6
17.9
39.40
40.87
%
1.76
67
676
65
667
0.79
0.27
14.0
9.1
27.86
25.92
u/l
0.34
65
644
27
239
1.20
0.26
4.3
3.4
20.41
41.49
ng/l
0.94
17
165
6
81
0.72
0.25
1.8
2.0
—
—
—
0
0
9
111
0.78
0.22
2.1
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
37.71
—
0
12
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
19
167
1.19
0.19
4.3
3.8
20.58
25.55
%
—
10
80
36
334
1.15
0.19
5.8
3.1
0.00
0.00
estimate
-0.00
11
59
67
683
0.80
0.19
36.0
17.5
90.49
90.77
fl
0.20
67
676
37
346
1.14
0.17
6.0
3.1
0.00
0.00
estimate
-0.00
11
56
36
342
1.10
0.11
6.1
3.1
0.00
0.00
estimate
-0.00
11
59
6
73
0.81
0.08
1.8
2.0
—
—
—
0
0
67
657
1.21
0.07
28.7
14.8
66.81
77.38
umol/l
4.37
67
649
27
257
1.08
0.06
2.0
2.0
84.58
97.36
pmol/l
0.76
12
126
26
254
1.04
0.00
6.9
3.1
0.00
0.02
estimate
—
9
48
18
182
0.99
0.00
7.9
2.9
0.00
0.00
estimate
—
10
44
20
205
0.97
0.00
2.4
3.8
1.82
5.48
mg/mmol
1.58
13
135
44
436
1.02
0.00
3.1
3.0
44.95
38.90
u/l
0.27
44
415
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
4.94
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
6.57
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
61.20
—
0
7
0
6
0.00
-0.00
0.0
2.7
—
14.12
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS – Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).