No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1132 |
4. Check minimum number of eventsNone |
1132 |
5. Include endpointsNone |
1132 |
6. Filter based on genotype QC (FinnGen only) |
1036 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q6[5-9]|Q7
- Name in latin
- Deformitates congenitae pedum
Similar endpoints
↥List of similar endpoints to
Congenital deformities of feet
based on the number of shared cases.
Similar with more cases:
- Congenital deformities of feet, including avohilmo
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations and deformations of the musculoskeletal system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12688 | 5897 | 6770 |
| Only index persons | 10876 | 5130 | 5746 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.17 | 0.19 |
| Only index persons | 0.20 | 0.19 | 0.22 |
| Median age at first event (years) | |||
| Whole population | 10.23 | 12.31 | 8.35 |
| Only index persons | 12.68 | 14.50 | 11.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1036 | 648 | 388 |
| Unadjusted period prevalence (%) | 0.21 | 0.23 | 0.18 |
| Median age at first event (years) | 39.81 | 41.05 | 37.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1077
- Matched controls
- 10770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q66.7
ICD-10 Finland
Pes cavus
1299.7
307.7
352
*
Q66.5
ICD-10 Finland
Congenital pes planus
212.2
307.7
192
11
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
254.6
234
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
19.1
142.2
115
67
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
6.3
136.6
275
554
Q66.8
ICD-10 Finland
Other congenital deformities of feet
1424.0
132.2
126
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
20.4
106.7
83
44
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
37.7
102.8
64
18
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
9.0
95.7
125
155
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
475.6
89.6
88
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
6.7
87.4
150
253
Q66.2
ICD-10 Finland
Metatarsus varus
440.2
83.2
82
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
30.5
82.9
55
19
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
5.1
79.5
189
431
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
8.1
73.2
103
139
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
7.5
64.4
96
138
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
21.8
64.1
48
23
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
9.5
59.9
73
82
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
16.0
56.6
49
32
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
7.2
56.3
87
130
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
10.1
56.2
65
68
M19.2
ICD-10 Finland
Other secondary arthrosis
14.1
53.9
50
37
NH1AD
NOMESCO Finland
Ankle and foot CT
8.3
53.7
73
94
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
9.6
52.6
63
69
Q66.4
ICD-10 Finland
Talipes calcaneovalgus
+∞
52.5
50
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
6.2
49.5
88
152
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
499.5
48.8
48
*
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
7.1
48.1
75
113
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
11.3
48.0
51
47
Q66.6
ICD-10 Finland
Other congenital valgus deformities of feet
+∞
47.2
45
*
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
+∞
45.1
43
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
4.1
44.8
134
360
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.6
41.5
105
248
L17
ICPC
Foot/toe symptom/complaint
2.4
40.8
428
2314
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
74.4
38.2
43
6
L16
ICPC
Ankle symptom/complaint
2.8
38.2
230
950
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
8.2
37.7
51
65
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.4
37.1
146
471
SPAT1229
SPAT
Assessment of need for aid
4.7
36.4
89
204
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
49.7
35.9
43
9
L84
ICD-10 Finland
Corns and callosities
5.6
35.5
70
133
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.7
33.2
81
185
TQW40
NOMESCO Finland
Remowal of suture of skin
3.7
33.0
114
337
B01AB05
ATC
enoxaparin; parenteral
2.3
32.5
324
1684
Q66.3
ICD-10 Finland
Other congenital varus deformities of feet
326.3
32.0
32
*
9341
FHL
Reduction and plaster or plaster exchange
170.0
31.9
33
*
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
9.2
31.7
39
44
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.0
31.1
92
244
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
9.3
30.5
37
41
TNH36
NOMESCO Finland
Custom molded cast of pes equinovarus
+∞
30.4
29
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.8
30.3
178
720
M79.6
ICD-10 Finland
Pain in limb
2.1
29.9
525
3382
ZXA00
NOMESCO Finland
Right side
2.3
28.7
266
1331
M77.4
ICD-10 Finland
Metatarsalgia
3.3
28.2
117
388
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
7.9
28.2
39
51
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.1
27.2
48
82
ZXA05
NOMESCO Finland
Left side
2.3
27.0
246
1218
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
35.0
26.6
34
10
NHL30
NOMESCO Finland
Suture or reinsertion of tendon of foot
10.3
26.6
30
30
M76.7
ICD-10 Finland
Peroneal tendinitis
10.6
26.3
29
28
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
5.5
25.6
50
94
9343
FHL
Posterior release or posteromedical release
255.8
24.8
25
*
L28
ICPC
Limited function/disability (L)
2.5
24.7
185
837
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
4.9
24.3
54
114
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
24.2
378
2292
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
23.9
151
630
WX320
NOMESCO Finland
Spinalanesthesy
2.2
23.3
256
1361
M25.5
ICD-10 Finland
Pain in joint
1.9
23.0
412
2608
-, ,
ICD-10 Finland
6.6
22.7
37
58
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
8.7
22.0
28
33
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
21.9
69
191
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
21.9
482
3251
N02AX02
ATC
tramadol; systemic, rectal
1.9
21.8
415
2670
L82
ICPC
Congenital anomaly musculoskeletal
224.4
21.7
22
*
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
27.0
21.4
29
11
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
7.1
21.3
32
46
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
21.2
291
1672
R4110
NOMESCO Finland
Physiotherapy
2.0
21.1
307
1801
NHT62
NOMESCO Finland
Surgical procedure for correction of pes equinovarus
+∞
20.9
20
*
NHG20
NOMESCO Finland
Fusion of talocrural joint
38.0
20.8
26
7
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
20.7
123
496
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
49.0
20.2
24
5
Z31.5
ICD-10 Finland
Genetic counselling
2.9
20.0
102
380
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
19.8
132
563
Q66.1
ICD-10 Finland
Talipes calcaneovarus
74.9
19.8
22
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
19.3
443
2994
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.1
19.2
85
292
N03AX12
ATC
[U] gabapentin; oral
2.3
18.7
168
817
N03AX16
ATC
[U] pregabalin
2.0
18.5
226
1240
NH3BG
NOMESCO Finland
MRI of foot
7.7
17.9
25
33
NHE15
NOMESCO Finland
Suture or reinsertion of ligament of ankle
7.2
17.4
26
37
Z50.1
ICD-10 Finland
Other physical therapy
3.4
17.3
64
197
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.9
16.5
36
75
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.9
16.0
35
73
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.0
15.8
73
257
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
14.0
15.5
26
19
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
14.0
15.5
26
19
N02BE01
ATC
paracetamol; systemic, rectal
2.0
14.8
923
8050
NF1AA
NOMESCO Finland
Hip X-ray examination
2.8
14.7
78
296
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
14.7
72
262
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
14.5
135
664
A46
ICD-10 Finland
Erysipelas
2.2
14.4
130
631
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
14.3
84
336
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.0
14.3
168
903
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
14.0
134
666
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
16.0
14.0
22
14
M01AH05
ATC
etoricoxib; oral
1.6
13.9
631
4978
L04AA01
ATC
[U] ciclosporin
6.6
13.7
22
34
Z3226
NOMESCO Finland
Physiotherapist
1.9
13.6
196
1128
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
13.5
235
1436
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
13.3
87
367
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.7
13.1
30
65
J01FF01
ATC
clindamycin; systemic
1.7
13.0
270
1733
S18
ICPC
Laceration/cut
1.6
12.9
464
3438
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.8
12.8
67
253
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
3.6
12.6
42
121
9111
FHL
Plastering under anesthesia
20.3
12.5
18
9
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.9
12.4
36
94
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
4.6
12.4
29
64
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
12.4
116
571
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
12.3
356
2491
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
12.1
70
278
NH1AA, ,
SPAT
2.8
12.0
59
215
A02BC02
ATC
pantoprazole; systemic
1.6
12.0
626
5027
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
10.2
12.0
23
23
R4180
NOMESCO Finland
Podiatric therapy
5.7
12.0
22
39
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
11.8
37
102
M03BX02
ATC
tizanidine; oral
1.6
11.7
620
4983
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.5
11.7
28
63
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.9
11.7
34
89
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
11.7
202
1226
M01AC06
ATC
meloxicam; systemic, rectal
1.7
11.7
308
2101
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
11.6
119
606
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.9
11.6
55
197
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.6
11.5
68
273
AA1AD
NOMESCO Finland
CT of head and brain
1.7
11.5
224
1408
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
+∞
11.5
11
*
NH3AA, ,
SPAT
2.3
11.4
89
407
R5110, ,
SPAT
2.4
11.1
79
346
WX213
NOMESCO Finland
Lower leg blockade
10.2
11.0
21
21
Z3231
NOMESCO Finland
Registered nurse
1.7
11.0
278
1871
ZA7.0
ICD-10 Finland
Ankle and foot
4.9
11.0
24
50
N02BF01
ATC
gabapentin; oral
2.1
11.0
109
549
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.7
10.9
59
227
N06AX21
ATC
duloxetine; oral
1.9
10.8
135
738
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
10.7
292
2001
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
5.6
10.7
20
36
B01AB04
ATC
dalteparin; parenteral
2.9
10.7
51
183
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
10.6
106
534
SPAT1153
SPAT
Removal of sutures
1.7
10.5
261
1748
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
10.5
242
1590
7545A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES VARUS CONGENITUS]
+∞
10.4
10
*
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
5.5
10.4
20
37
B01AB10
ATC
tinzaparin; parenteral
2.1
10.4
106
539
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
10.3
88
417
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
10.3
148
847
UJF32
NOMESCO Finland
Coloscopy
1.7
10.2
203
1280
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.8
10.2
31
84
NHG82
NOMESCO Finland
Fusion of other tarsal joint
8.0
10.1
22
28
NHQ40
NOMESCO Finland
Amputation of toe
8.0
10.1
22
28
N02BF02
ATC
pregabalin; oral
2.3
10.1
77
348
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.8
10.0
176
1072
9344
FHL
Other operation on soft tissue of the foot
40.5
10.0
12
*
A03FA02
ATC
cisapride; oral, rectal
2.5
10.0
64
268
M01AH01
ATC
celecoxib; oral
1.9
9.9
140
796
ZXA10
NOMESCO Finland
Bilateral
1.8
9.9
168
1013
NHT99
NOMESCO Finland
Other operation on ankle or foot
26.3
9.8
13
5
WX212
NOMESCO Finland
Femoral plexus blockade
4.0
9.8
27
68
NH1AI
NOMESCO Finland
Cone beam CT of ankle
8.8
9.8
20
23
S97
ICPC
Chronic ulcer skin
2.6
9.8
57
228
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.7
399
2993
M02AA07
ATC
piroxicam; topical
1.6
9.6
272
1877
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
3.9
9.5
28
74
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
9.5
90
445
A01
ICPC
Pain general/multiple sites
2.0
9.5
109
579
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
9.4
272
1883
NGL66
NOMESCO Finland
Transposition of tendon of knee or lower leg
21.9
9.4
13
6
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
9.3
119
655
C03CA01
ATC
furosemide; systemic
1.8
9.3
163
991
J01AA02
ATC
doxycycline; systemic
1.5
9.2
699
5928
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
13.8
9.2
15
11
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
9.2
207
1348
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
9.1
472
3704
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
9.0
72
332
R52.9
ICD-10 Finland
Pain, unspecified
1.9
9.0
114
625
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
9.0
231
1552
M22.0
ICD-10 Finland
Recurrent dislocation of patella
3.9
9.0
26
68
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
18.8
8.9
13
7
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.9
249
1710
XKC03
NOMESCO Finland
Water cystometry
3.4
8.8
31
93
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.3
8.8
32
98
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
8.8
74
349
M19.9
ICD-10 Finland
Arthrosis, unspecified
2.9
8.8
41
146
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.6
8.7
48
187
H02AB04
ATC
methylprednisolone; systemic
1.9
8.6
123
701
A02BC01
ATC
omeprazole; systemic
1.6
8.6
231
1567
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.2
8.6
75
359
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
8.3
8.6
18
22
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
7.0
8.6
20
29
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
8.5
144
864
SPAT1210
SPAT
Application of cast or individual aid
2.6
8.5
50
201
D07AD01
ATC
clobetasol; topical
1.7
8.5
155
952
S83.0
ICD-10 Finland
Dislocation of patella
2.8
8.4
40
144
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
8.3
181
1164
9345
FHL
Tendon or tendon transplantation
+∞
8.3
8
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
8.3
241
1665
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.3
393
3014
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
8.2
109
609
A02BC05
ATC
esomeprazole; systemic
1.5
8.1
348
2612
J01DB01
ATC
cefalexin; oral
1.6
8.1
866
7771
NH3DG
NOMESCO Finland
Very extensive MRI of foot
22.2
8.0
11
5
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.6
8.0
26
74
A28
ICPC
Limited function/disability NOS
1.9
7.9
108
607
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
4.7
7.9
18
39
NH2AA
NOMESCO Finland
Heel X-ray examination
7.8
7.9
17
22
M01AE02
ATC
naproxen; oral, rectal
1.4
7.8
610
5119
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
7.8
57
253
M54.5
ICD-10 Finland
Low back pain
1.5
7.8
372
2847
NHU10
NOMESCO Finland
Removal of external fixation device from ankle or foot
8.5
7.8
16
19
J01DA01
ATC
[U] cefalexin
1.4
7.8
585
4876
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
15.1
7.7
12
8
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
7.7
213
1453
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
7.7
138
843
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
4.6
7.7
18
40
R60.0
ICD-10 Finland
Localized oedema
1.9
7.7
99
547
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
7.6
126
751
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
11.9
7.6
13
11
9165
FHL
Removal of osteosynthesis material
3.9
7.5
22
58
M01AX17
ATC
nimesulide; oral
1.7
7.5
160
1023
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
7.5
126
756
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.5
99
552
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
3.0
7.4
32
109
A02BC03
ATC
lansoprazole; oral
1.6
7.3
215
1485
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.3
598
5037
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
10.9
7.3
13
12
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
7.3
7
*
Q74.1
ICD-10 Finland
Congenital malformation of knee
+∞
7.3
7
*
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
7.3
7
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
7.3
224
1564
G04BD11
ATC
fesoterodine; oral
3.9
7.3
21
55
M54.2
ICD-10 Finland
Cervicalgia
1.9
7.3
91
498
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
7.2
134
825
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.4
7.2
48
205
M20.2
ICD-10 Finland
Hallux rigidus
3.0
7.2
31
106
X58
ICD-10 Finland
Exposure to other specified factors
1.6
7.1
177
1177
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.2
7.0
18
43
M48.0
ICD-10 Finland
Spinal stenosis
2.0
7.0
80
424
SPAT1301
SPAT
No procedures
1.5
7.0
292
2171
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.0
155
1001
A06AD11
ATC
lactulose; oral
1.8
7.0
97
549
G47.3
ICD-10 Finland
Sleep apnoea
1.6
7.0
200
1374
H02AB06
ATC
prednisolone; systemic
1.4
7.0
417
3316
NH3CG
NOMESCO Finland
Extensive MRI of foot
6.4
7.0
17
27
G04BD12
ATC
mirabegron; oral
1.9
6.9
83
447
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
6.9
82
441
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.6
6.9
22
62
S20
ICPC
Corn/callosity
3.6
6.9
22
62
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
3.4
6.9
24
72
SPAT1216
SPAT
Assessment of functional ability
1.8
6.8
105
613
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.6
6.8
39
155
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
6.8
198
1364
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
6.8
96
547
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
16.8
6.7
10
6
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.7
187
1274
J01CF02
ATC
cloxacillin; systemic
3.9
6.7
19
49
S01
ICPC
Pain/tenderness of skin
2.3
6.7
50
225
L15
ICPC
Knee symptom/complaint
1.5
6.7
250
1817
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
4.1
6.6
18
45
ZXD05
NOMESCO Finland
Urgent procedure
1.5
6.6
276
2048
NH1BG, ,
SPAT
3.0
6.6
29
100
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.6
195
1347
WX702
NOMESCO Finland
Supraglottic ventilation device
2.1
6.6
61
300
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.6
328
2519
WX214
NOMESCO Finland
Plexus blockade at the ankle
10.1
6.5
12
12
J01FA01
ATC
erythromycin; systemic
1.6
6.5
151
985
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
2.9
6.5
29
101
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
6.5
807
7243
XA402
NOMESCO Finland
ENMG
3.2
6.5
25
80
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.2
6.5
25
80
G04BD07
ATC
tolterodine; oral
2.7
6.5
33
124
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.4
794
7110
NGL64
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of knee or lower leg
70.3
6.4
7
*
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.4
297
2247
F34.1
ICD-10 Finland
Dysthymia
2.3
6.4
49
223
M66.5
ICD-10 Finland
Spontaneous rupture of unspecified tendon
14.4
6.4
10
7
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.4
381
3016
WZC00, ,
SPAT
1.6
6.4
163
1089
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.4
99
580
D01AE16
ATC
amorolfine; topical
1.8
6.3
86
483
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
8.2
6.3
13
16
M21.1
ICD-10 Finland
Varus deformity, not elsewhere classified
11.1
6.3
11
10
M24.2
ICD-10 Finland
Disorder of ligament
3.4
6.3
22
66
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.8
6.3
97
567
NFK20
NOMESCO Finland
Epiphysiodesis of femur
18.1
6.3
9
5
9115
FHL
Epiphysiodesis (in hip luxation trokanter 9408)
+∞
6.3
6
*
NHW10
NOMESCO Finland
Reoperation for deep infection in in surgery of ankle or foot
+∞
6.3
6
*
9348
FHL
Subtalo, triple or lime cuboid arthrodesis
+∞
6.3
6
*
Q74.9
ICD-10 Finland
Unspecified congenital malformation of limb(s)
+∞
6.3
6
*
Q74.3
ICD-10 Finland
Arthrogryposis multiplex congenita
+∞
6.3
6
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
6.2
82
456
NHF20
NOMESCO Finland
Operation for debridement of ankle joint, open
26.8
6.2
8
*
N04BC05
ATC
pramipexole; oral
2.1
6.2
58
286
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.2
784
7020
L04AD01
ATC
ciclosporin; systemic
3.1
6.2
25
82
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.9
6.2
76
414
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
6.2
104
624
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
5.4
6.2
17
32
L29
ICPC
Musculoskeletal sympt/complt other
1.8
6.1
86
488
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.1
6.1
59
295
M02AA10
ATC
ketoprofen; topical
1.7
6.1
122
767
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.2
6.1
49
228
M35.7
ICD-10 Finland
Hypermobility syndrome
3.2
6.0
23
73
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
5.2
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
136
638
2.30
16.44
3.0
2.4
77.16
75.61
ml/min/173m2
0.16
67
256
460
3279
1.70
15.70
14.0
9.0
1.15
1.14
inr
0.20
378
2703
340
2254
1.74
14.95
4.5
3.4
1.02
1.02
kg/l
1.07
229
1461
481
3552
1.64
13.80
8.8
6.9
1.21
1.22
mmol/l
1.23
461
3305
622
4967
1.60
12.41
5.0
3.4
0.00
3.13
estimate
0.80
115
999
540
4172
1.59
12.40
3.0
2.7
—
—
estimate
—
0
0
383
2727
1.63
12.37
4.5
3.2
18.24
82.15
e6/l
1.67
310
2025
468
3512
1.59
12.06
5.9
5.1
36.76
37.03
g/l
0.54
449
3316
622
4993
1.58
11.93
5.0
3.5
0.00
0.32
estimate
0.52
111
952
336
2346
1.63
11.60
2.6
2.1
310.35
242.91
u/l
0.33
315
2243
275
1825
1.68
11.58
3.6
2.6
6.08
7.13
e6/l
0.58
254
1659
116
589
2.09
11.42
4.8
4.6
74.36
75.83
ng/l
0.05
106
536
146
805
1.94
11.42
7.4
5.6
—
—
—
0
0
619
4991
1.56
11.42
6.0
5.1
6.35
6.47
mmol/l
0.82
593
4636
612
4926
1.56
11.35
5.0
3.4
0.01
0.00
estimate
0.42
113
1000
300
2057
1.64
11.05
3.5
2.7
335.77
327.84
umol/l
0.72
273
1879
229
1464
1.72
11.01
3.5
2.9
1.49
0.90
e6/l
0.94
135
718
358
2593
1.57
10.37
5.5
3.5
0.00
0.01
estimate
1.28
110
948
270
1829
1.64
10.34
1.3
1.3
15.43
27.67
iu/ml
3.26
82
519
154
892
1.85
10.33
2.0
1.9
—
—
—
0
0
138
776
1.89
10.14
8.9
9.3
1.04
0.77
mmol/l
0.38
121
659
44
151
3.00
10.02
1.8
1.5
—
—
—
0
0
138
784
1.87
9.82
9.1
9.3
5.08
5.15
kpa
0.48
133
758
769
6657
1.54
9.17
5.0
4.2
9.56
9.54
mm/h
0.02
740
6282
154
925
1.78
9.12
1.9
1.9
—
—
—
0
0
503
3997
1.48
9.11
9.6
7.3
1.21
1.21
mmol/l
0.21
462
3496
193
1237
1.68
9.06
2.0
2.0
—
—
—
0
0
978
9008
1.93
9.03
19.8
13.8
139.71
139.64
mmol/l
0.49
968
8823
255
1760
1.59
8.88
3.9
3.3
740.47
838.62
ng/l
0.29
210
1435
999
9277
2.06
8.87
19.2
12.8
20.53
21.58
mg/l
0.52
856
7352
648
5432
1.48
8.87
10.5
9.6
3.98
3.94
e9/l
0.18
577
4721
325
2376
1.53
8.74
4.4
3.1
0.59
0.36
e6/l
0.36
252
1675
368
2769
1.50
8.60
3.2
3.2
2.34
2.36
mmol/l
1.91
349
2563
976
9025
1.87
8.29
20.0
13.8
3.94
3.93
mmol/l
0.87
964
8810
243
1695
1.56
8.00
1.3
1.3
1.42
9.95
u/ml
6.10
91
657
471
3764
1.45
7.93
5.0
3.2
0.02
0.02
estimate
0.04
91
849
159
1016
1.66
7.48
9.0
7.6
104.77
104.49
mmol/l
0.35
159
1016
207
1425
1.56
7.15
2.1
2.6
2.42
2.43
mmol/l
0.50
189
1273
348
2684
1.44
6.85
3.5
2.6
63.88
60.96
u/l
0.12
329
2504
117
708
1.73
6.73
13.1
8.8
8.78
7.75
mmol/l
0.95
117
685
527
4395
1.39
6.53
7.1
6.3
10.56
11.17
umol/l
0.65
505
4166
359
2814
1.41
6.37
3.6
3.1
40.47
57.39
ng/l
0.25
223
1606
103
615
1.75
6.21
3.9
2.4
0.25
0.23
e6/l
0.09
96
580
206
1459
1.51
6.19
3.0
3.4
978.62
531.55
ng/l
0.41
142
933
275
2069
1.44
6.08
2.7
2.0
1.38
1.01
mg/l
0.37
216
1542
71
384
1.91
5.90
1.3
1.2
0.72
1.37
u/ml
—
6
23
42
188
2.28
5.73
2.0
1.6
7418.14
11238.90
e6/l
0.47
29
134
736
6602
1.36
5.17
9.5
7.6
80.23
79.19
u/l
0.27
716
6288
61
330
1.90
5.09
6.0
4.1
53.06
49.62
%
0.47
61
323
168
1200
1.47
4.79
3.0
2.4
30.80
29.37
s
1.50
163
1170
130
884
1.54
4.70
4.9
5.5
5.79
5.82
kpa
0.11
130
863
79
475
1.72
4.69
2.3
2.3
12.58
7.71
ug/l
0.44
72
433
17
53
3.24
4.63
6.5
2.9
863.65
1061.00
mg
0.29
17
53
98
628
1.62
4.57
1.4
1.5
—
—
—
0
0
112
742
1.57
4.54
2.8
2.8
—
—
—
0
0
126
858
1.53
4.52
5.1
5.6
2.11
1.61
mmol/l
1.05
116
731
808
7426
1.35
4.37
4.9
4.3
14.64
14.52
pmol/l
0.80
764
6904
89
564
1.63
4.35
1.8
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
37
181
2.08
4.14
5.6
4.5
0.28
0.37
iu/ml
1.12
23
99
183
1366
1.41
4.11
3.9
3.0
3.53
2.78
e6/l
0.49
91
623
99
653
1.57
4.11
2.9
3.7
4.67
4.74
pmol/l
0.20
93
588
345
2858
1.30
3.90
4.5
3.5
8.15
8.29
mmol/l
0.21
317
2501
75
472
1.63
3.79
1.5
1.7
9.14
8.40
u/l
0.15
56
375
475
4119
1.27
3.72
3.2
2.6
73.79
73.19
nmol/l
0.19
447
3836
110
763
1.49
3.64
5.2
5.3
5.02
4.74
kpa
0.62
110
746
37
191
1.97
3.61
1.5
1.4
—
—
—
0
0
116
815
1.47
3.61
1.5
1.3
183.80
332.57
u/ml
0.69
106
765
67
416
1.65
3.58
1.7
1.7
—
—
—
0
0
884
8322
1.35
3.46
5.0
4.2
5.76
5.74
mmol/l
0.17
856
7813
1008
9714
1.59
3.45
21.5
15.0
72.45
71.70
umol/l
0.36
998
9618
65
405
1.64
3.44
1.5
1.4
—
—
—
0
0
264
2144
1.31
3.40
2.7
2.2
—
—
—
0
0
7
10
7.04
3.36
4.7
8.4
—
—
—
0
0
28
134
2.12
3.36
4.0
2.4
17.08
17.07
%
0.01
28
129
175
1342
1.36
3.33
3.6
2.6
14.17
14.41
umol/l
0.16
166
1256
339
2855
1.27
3.28
1.4
1.5
1.43
1.71
u/ml
0.13
95
771
139
1036
1.39
3.15
1.5
1.6
1323.44
1167.86
nmol/l
0.99
106
796
67
432
1.59
3.11
1.6
2.0
4.28
5.60
iu/ml
0.28
18
91
12
35
3.46
3.11
5.5
2.2
124.25
101.28
ug/l
0.17
12
35
7
12
5.86
3.02
4.7
1.6
—
—
—
0
0
26
498
0.51
2.99
1.8
1.5
—
—
—
0
0
27
509
0.52
2.96
1.8
1.5
1.16
1.20
ratio
0.09
21
321
27
509
0.52
2.96
1.8
1.5
1.45
1.14
ratio
0.45
21
321
27
509
0.52
2.96
1.8
1.5
0.98
0.94
ratio
0.31
21
321
30
156
1.95
2.92
2.1
3.1
1.30
1.84
ratio
0.75
22
84
275
2286
1.27
2.92
4.3
4.2
7.63
9.90
mg/mmol
0.46
189
1460
63
408
1.58
2.89
1.9
1.4
—
—
—
0
0
852
8045
1.28
2.79
6.3
5.2
37.82
37.88
mmol/mol
0.06
820
7685
148
1139
1.35
2.76
3.8
2.6
24.14
24.18
%
0.01
139
1075
904
8610
1.31
2.72
5.9
5.2
1.82
1.81
mu/l
0.03
877
8134
79
546
1.48
2.71
4.9
5.5
1.26
1.33
mmol/l
0.09
56
397
190
1522
1.30
2.68
1.6
1.6
453.92
32551527.51
pmol/l
1.69
170
1321
1052
10305
1.90
2.65
27.6
19.3
4.58
4.58
e12/l
0.16
1039
10110
39
229
1.73
2.62
2.5
3.0
2.38
1.99
index
0.14
24
127
53
339
1.59
2.59
6.2
6.3
9.43
9.08
kpa
0.68
53
330
1052
10309
1.88
2.58
27.6
19.4
6.73
6.65
e9/l
0.67
1042
10107
1051
10297
1.86
2.57
27.6
19.4
257.36
258.18
e9/l
0.16
1042
10120
40
239
1.70
2.54
1.6
1.9
3.03
16.06
e6/l
1.64
30
173
87
624
1.43
2.49
4.9
5.3
5.08
5.11
kpa
0.13
87
603
159
1258
1.31
2.46
3.7
2.5
2.38
2.40
g/l
0.14
148
1167
40
242
1.68
2.44
1.6
1.9
100.94
161.02
e6/l
0.30
31
182
390
3427
1.22
2.44
2.1
1.9
96.88
96.96
pmol/l
0.01
202
1820
7
17
4.14
2.36
2.4
6.0
—
—
—
0
0
111
839
1.36
2.35
3.2
2.4
10.65
13.21
nmol/l
3.26
99
786
270
2296
1.23
2.31
2.6
2.2
2.79
2.61
mg/l
0.69
231
1996
323
2810
1.21
2.20
1.8
1.8
—
—
—
0
0
999
9710
1.40
2.17
13.6
10.5
28.12
27.02
u/l
0.85
982
9490
548
5012
1.19
2.15
3.8
3.2
94.64
93.96
ug/l
0.03
519
4754
49
325
1.53
2.09
4.3
3.5
163.07
178.24
%
0.67
49
317
107
821
1.34
2.07
3.0
3.0
11.32
10.43
g/l
1.31
99
759
887
8499
1.25
2.05
16.1
11.4
91.82
91.89
ml/min/173m2
0.03
820
7627
34
209
1.65
2.00
1.4
1.3
—
—
—
0
0
43
630
0.67
1.83
1.5
1.5
—
—
—
0
0
16
80
2.02
1.80
1.3
1.3
1.52
1.31
nmol/l
0.28
16
72
370
3312
1.18
1.79
3.9
3.4
30.86
31.72
u/l
0.20
354
3156
57
405
1.43
1.78
1.5
2.3
40.19
39.70
u/l
0.06
51
375
84
639
1.34
1.75
1.0
1.2
—
1.02
—
0
6
15
283
0.52
1.74
1.7
1.2
—
—
—
0
0
8
30
2.68
1.72
1.5
1.5
11.56
8.01
ug/l
—
8
30
5
13
3.86
1.71
4.8
5.9
—
—
—
0
0
913
8817
1.23
1.71
5.1
4.4
4.60
4.70
mmol/l
2.59
888
8424
38
252
1.53
1.67
1.5
1.5
0.29
0.36
nmol/l
0.56
33
208
62
453
1.39
1.67
3.5
4.8
129.73
131.04
g/l
0.19
62
441
41
277
1.50
1.66
1.2
1.2
—
—
—
0
0
41
277
1.50
1.66
1.2
1.2
—
—
—
0
0
917
8867
1.23
1.64
5.6
4.8
2.75
2.80
mmol/l
0.95
891
8448
26
158
1.66
1.63
1.2
1.2
—
—
—
0
0
27
166
1.64
1.62
1.3
1.2
1.70
3.69
u/ml
—
10
55
75
976
0.75
1.62
1.7
1.6
1192.53
983.11
mu/l
1.01
69
846
92
720
1.30
1.60
1.6
1.5
23.51
22.23
iu/l
0.15
76
598
23
136
1.71
1.59
1.1
1.2
—
17.43
—
0
7
860
8272
1.20
1.59
4.3
3.7
1.27
1.25
mmol/l
0.36
836
7835
92
721
1.30
1.58
1.1
1.0
—
—
—
0
0
73
554
1.34
1.57
1.7
1.6
0.19
0.29
mg/l
1.39
35
251
59
434
1.38
1.54
1.4
1.8
—
—
—
0
0
35
233
1.52
1.53
10.7
7.1
1378.83
322.03
iu/ml
—
6
32
26
162
1.62
1.50
1.1
1.4
—
—
—
0
0
26
162
1.62
1.50
1.1
1.4
—
—
—
0
0
26
163
1.61
1.47
1.5
2.0
—
—
—
0
0
69
895
0.76
1.47
4.9
4.0
31.10
31.69
%
0.19
59
644
22
132
1.68
1.46
1.1
1.2
—
—
—
0
0
7
28
2.51
1.45
3.6
2.5
0.57
0.61
mmol/l
—
7
28
107
868
1.26
1.42
3.0
2.5
29.45
95.92
u/l
0.63
91
731
93
742
1.28
1.42
3.1
2.4
8204.08
5554.78
u/l
0.33
32
316
32
214
1.51
1.39
2.0
1.6
—
—
—
0
0
282
2522
1.16
1.34
1.5
1.5
2.04
2.18
g/l
0.80
180
1579
184
1591
1.19
1.32
2.2
2.7
111.74
107.54
ug/g
0.10
157
1278
241
2132
1.17
1.32
1.7
1.5
21.38
20.25
nmol/l
0.57
224
1849
35
243
1.46
1.29
2.4
1.8
—
—
—
0
0
35
243
1.46
1.29
1.2
1.8
3.61
3.66
mmol/l
0.10
35
231
5
18
2.79
1.28
14.4
6.3
5.74
5.98
kpa
—
5
18
5
18
2.79
1.28
14.2
6.3
6.40
5.18
kpa
—
5
18
5
18
2.79
1.28
1.0
1.0
—
—
—
0
0
36
252
1.44
1.27
1.4
1.5
265.16
292.71
ug/g
0.34
19
153
155
1327
1.20
1.25
3.4
3.8
24.54
21.45
%
1.21
55
500
23
147
1.58
1.23
6.0
2.7
5.26
4.90
kpa
2.31
23
147
77
612
1.28
1.23
1.2
1.3
70.75
38.94
au/ml
—
8
43
9
45
2.01
1.23
1.0
1.0
—
—
—
0
0
10
49
2.05
1.22
1.1
1.1
—
—
—
0
0
25
164
1.54
1.21
1.4
1.3
3.80
5.25
u/ml
0.37
15
72
15
86
1.75
1.19
3.5
3.3
—
—
—
0
0
399
3686
1.13
1.17
2.0
1.9
1.39
1.37
mmol/l
0.10
354
3237
191
1676
1.17
1.16
4.0
4.3
2.60
1.81
ug/l
0.37
178
1537
708
6772
1.13
1.16
3.6
3.3
41.07
40.12
u/l
0.14
682
6493
8
39
2.06
1.15
1.3
1.3
—
—
—
0
0
5
20
2.51
1.15
3.2
1.5
—
—
—
0
0
16
258
0.61
1.13
1.4
1.3
—
—
—
0
0
122
1036
1.20
1.09
3.7
3.3
5.34
6.83
umol/l
1.14
108
893
23
152
1.52
1.09
2.5
2.5
45.33
96.52
ug/min
0.96
17
97
49
376
1.32
1.05
1.6
1.3
—
—
—
0
0
5
22
2.28
1.03
1.2
1.4
—
—
—
0
0
5
22
2.28
1.03
1.0
1.2
—
—
—
0
0
119
1386
0.84
1.02
1.7
1.8
3.46
3.51
ratio
0.18
90
1044
81
666
1.23
1.01
2.3
2.4
12.12
19.81
au/ml
—
8
79
5
23
2.18
0.98
2.8
3.8
4.66
4.72
kpa
—
5
23
5
23
2.18
0.98
2.8
3.8
10.28
10.99
kpa
—
5
23
81
669
1.23
0.97
1.3
1.4
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
7
36
1.95
0.97
2.0
1.1
80.14
93.89
%
—
7
36
7
36
1.95
0.97
1.4
1.7
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
7
37
1.90
0.94
1.9
1.3
—
—
—
0
0
7
37
1.90
0.94
1.9
1.3
—
—
—
0
0
772
7468
1.12
0.92
3.9
3.6
—
—
—
0
0
9
52
1.74
0.92
3.7
4.3
0.67
0.77
index
—
9
52
9
52
1.74
0.92
1.4
1.2
—
—
—
0
0
17
110
1.55
0.91
1.3
1.4
—
—
—
0
0
23
160
1.45
0.89
1.1
1.1
—
—
—
0
0
114
983
1.18
0.89
2.5
2.0
332.41
374.30
nmol/l
1.58
106
929
68
558
1.23
0.89
5.1
3.4
1.22
1.23
mmol/l
1.89
63
481
14
87
1.62
0.88
1.5
1.2
—
28.80
—
0
5
15
96
1.57
0.84
1.5
1.7
—
—
—
0
0
14
88
1.60
0.84
1.0
1.1
—
—
—
0
0
898
8780
1.14
0.84
4.9
4.3
1.43
1.46
mmol/l
1.38
874
8358
20
137
1.47
0.84
1.1
1.1
1.38
1.44
g/l
0.44
20
125
33
248
1.34
0.84
1.2
1.1
35.35
14.04
au/ml
—
8
73
104
895
1.18
0.84
1.4
1.3
87.63
146.85
u/ml
1.32
43
350
8
46
1.74
0.82
1.3
1.3
—
—
—
0
0
8
47
1.71
0.80
1.1
1.7
—
—
—
0
0
19
131
1.46
0.78
1.2
1.6
—
—
—
0
0
14
91
1.55
0.75
5.2
7.5
6.34
6.92
mmol/l
0.41
14
73
5
24
2.09
0.74
3.8
1.9
4.86
5.59
nmol/l
—
5
24
7
39
1.80
0.72
1.4
1.9
133.57
128.15
%
—
7
39
7
39
1.80
0.72
1.1
1.2
—
—
—
0
0
25
186
1.35
0.70
1.3
1.4
735.85
361.45
mu/l
0.76
20
152
12
77
1.56
0.68
2.8
2.1
33.17
32.69
pg
0.15
12
77
5
91
0.55
0.67
1.8
1.4
62.29
35.97
nmol/l
—
5
79
19
136
1.40
0.67
1.3
1.1
—
1.16
—
0
9
202
1853
1.11
0.67
1.7
1.5
—
—
—
0
0
23
171
1.35
0.66
1.4
1.6
—
—
—
0
0
32
251
1.28
0.64
1.7
1.8
—
—
—
0
0
26
198
1.32
0.64
1.4
1.2
—
—
—
0
0
14
95
1.48
0.64
1.2
1.1
—
—
—
0
0
45
370
1.23
0.62
5.4
2.8
1.02
1.02
ratio
0.80
38
342
23
173
1.34
0.62
1.4
1.5
—
—
—
0
0
5
30
1.67
0.61
2.0
1.3
—
—
—
0
0
5
30
1.67
0.61
2.0
1.3
—
—
—
0
0
5
30
1.67
0.61
3.4
2.2
86.60
129.76
ng/l
—
5
30
16
113
1.42
0.61
1.0
1.1
—
—
—
0
0
21
156
1.35
0.61
8.2
2.9
9.20
6.73
pmol/l
0.89
21
156
8
52
1.54
0.59
1.5
1.1
—
—
—
0
0
14
197
0.71
0.59
1.0
1.1
2.09
3.82
eliau/ml
—
8
92
31
246
1.27
0.58
1.2
1.7
—
—
—
0
0
53
449
1.19
0.56
1.4
1.9
4.35
3.69
mg/l
0.27
38
316
95
1066
0.88
0.55
1.4
1.6
3.44
3.46
mmol/l
0.08
66
730
17
125
1.37
0.54
1.3
1.3
—
—
—
0
0
9
61
1.48
0.53
1.7
2.8
29.67
28.52
umol/l
—
9
56
9
61
1.48
0.53
4.4
2.3
—
—
—
0
0
11
74
1.49
0.53
1.9
1.1
112.91
111.99
pmol/l
0.03
11
74
9
62
1.46
0.53
7.8
3.6
1214.33
652.98
u/ml
—
9
62
6
40
1.50
0.51
1.2
1.8
—
—
—
0
0
6
41
1.47
0.50
1.3
1.4
—
—
—
0
0
45
382
1.19
0.48
1.6
1.6
11.47
7.98
u/ml
—
8
95
7
46
1.53
0.48
1.1
1.2
111.00
112.45
%
—
7
38
7
111
0.63
0.48
1.9
1.7
—
—
—
0
0
13
177
0.73
0.47
2.6
3.5
21.00
25.66
mg/l
—
7
122
7
48
1.46
0.47
1.1
1.1
0.29
0.29
g/l
—
7
40
16
120
1.34
0.46
1.1
1.7
—
—
—
0
0
7
49
1.43
0.46
1.1
2.6
—
—
—
0
0
7
49
1.43
0.46
1.1
2.6
—
—
—
0
0
11
77
1.43
0.45
1.1
1.3
0.68
0.62
ratio
—
6
40
20
156
1.29
0.45
2.3
2.0
—
—
—
0
0
33
275
1.21
0.44
2.0
1.9
—
—
—
0
0
20
157
1.28
0.43
1.3
1.8
—
—
—
0
0
5
31
1.62
0.43
1.0
1.6
—
—
—
0
0
27
221
1.23
0.42
2.0
2.9
—
—
—
0
0
8
56
1.43
0.42
1.0
1.7
—
—
—
0
0
6
92
0.65
0.42
2.0
1.8
—
—
—
0
0
12
87
1.38
0.42
1.2
1.2
—
—
—
0
0
11
150
0.73
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
60
1.34
0.40
1.1
1.1
—
—
—
0
0
12
88
1.37
0.40
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
30
252
1.20
0.38
2.2
2.8
6.14
6.74
umol/l
0.13
18
189
24
197
1.22
0.38
1.5
1.4
19.33
19.91
u/l
0.03
18
168
22
179
1.23
0.37
2.2
1.9
0.00
0.00
g/l
-0.00
22
173
24
198
1.22
0.36
2.1
1.9
0.00
0.02
g/l
0.50
24
184
12
90
1.34
0.36
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
1.2
1.8
—
—
—
0
0
6
44
1.37
0.34
1.3
1.4
319.65
609.30
u/l
—
6
44
6
45
1.34
0.33
1.2
1.8
—
—
—
0
0
41
360
1.14
0.32
1.3
1.5
0.04
0.04
iu/ml
0.03
12
55
12
92
1.31
0.32
1.2
1.1
—
83.75
—
0
8
12
92
1.31
0.32
1.2
1.1
—
—
—
0
0
15
119
1.26
0.32
1.1
1.1
—
—
—
0
0
149
1404
1.07
0.31
2.6
2.3
—
—
—
0
0
18
147
1.23
0.31
3.1
3.0
28.76
23.77
nmol/l
0.82
18
141
18
218
0.82
0.30
1.0
1.1
—
—
—
0
0
10
75
1.34
0.30
2.6
4.1
—
—
—
0
0
14
111
1.26
0.30
1.1
1.1
—
—
—
0
0
26
222
1.18
0.29
1.4
1.5
—
—
—
0
0
7
57
1.23
0.29
1.0
1.3
—
—
—
0
0
65
594
1.10
0.28
1.6
1.6
305.89
299.53
mu/l
0.06
56
536
14
112
1.25
0.28
1.2
1.2
—
—
—
0
0
10
76
1.32
0.28
1.2
1.1
—
—
—
0
0
12
94
1.28
0.28
1.2
1.1
—
—
—
0
0
19
225
0.84
0.26
1.4
1.6
—
—
—
0
0
18
150
1.20
0.26
1.6
1.5
—
—
—
0
0
12
95
1.27
0.26
1.2
1.1
—
—
—
0
0
9
74
1.22
0.25
1.3
1.6
—
—
—
0
0
9
74
1.22
0.25
1.3
1.6
—
—
—
0
0
9
74
1.22
0.25
1.3
1.6
—
—
—
0
0
66
609
1.09
0.25
3.3
4.4
3.44
14.30
ug/l
0.86
52
483
96
1021
0.93
0.24
3.0
2.7
0.73
0.69
ug/l
0.08
51
539
5
38
1.32
0.23
1.0
1.1
36.10
39.01
iu/ml
—
5
38
38
342
1.12
0.23
1.1
1.1
7.59
5.93
u/ml
0.22
19
212
12
97
1.24
0.23
1.6
1.4
4.27
3.76
u/ml
—
7
49
5
40
1.25
0.22
2.8
4.3
3.20
1.39
%
—
5
40
46
502
0.91
0.21
1.1
1.1
1.49
1.51
g/l
0.29
46
502
0
10
0.00
0.21
0.0
2.1
—
0.70
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
294
2859
1.04
0.21
4.3
2.8
0.00
0.04
estimate
0.83
94
832
30
268
1.12
0.21
1.3
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
29
259
1.12
0.20
1.5
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
18.7
8.4
47.87
341.99
ug/l
—
6
34
30
334
0.90
0.20
1.1
1.1
3.47
2.11
u/ml
0.34
17
186
9
115
0.78
0.20
1.4
1.6
—
—
—
0
0
12
99
1.21
0.19
1.2
1.1
—
—
—
0
0
6
52
1.15
0.19
1.2
1.4
—
53.33
—
0
6
6
53
1.13
0.18
1.7
2.4
64.33
51.70
umol/l
—
6
48
22
194
1.14
0.18
2.2
1.9
0.00
0.00
g/l
-0.00
22
173
5
69
0.72
0.17
1.0
1.1
1279.60
1632.93
miu/ml
—
5
69
44
408
1.08
0.16
1.7
1.8
—
—
—
0
0
8
69
1.16
0.16
1.3
1.2
—
—
—
0
0
36
331
1.09
0.16
1.1
1.1
0.40
1.20
u/ml
1.26
15
163
8
73
1.10
0.15
1.0
1.7
—
—
—
0
0
29
317
0.91
0.15
1.5
2.1
2.77
4.30
iu/l
—
7
140
19
170
1.12
0.13
1.2
1.1
4.43
130.91
iu/ml
—
7
49
34
366
0.93
0.13
1.7
1.5
—
—
—
0
0
9
109
0.82
0.13
1.0
1.1
—
—
—
0
0
48
509
0.94
0.13
1.2
1.1
0.87
0.89
g/l
0.39
48
509
18
161
1.12
0.13
3.3
2.9
1.67
1.42
mmol/l
0.29
18
154
10
116
0.86
0.12
1.8
1.3
—
—
—
0
0
10
116
0.86
0.12
1.8
1.3
—
—
—
0
0
34
318
1.07
0.11
1.3
1.4
259.00
217.04
u/ml
0.47
22
174
10
115
0.87
0.10
1.0
1.1
—
—
—
0
0
26
241
1.08
0.10
1.2
1.4
75.08
158.43
pmol/l
0.91
26
235
40
380
1.05
0.09
1.1
1.2
3.28
3.33
u/ml
0.01
19
216
6
54
1.11
0.09
1.0
1.1
75.22
167.02
iu/ml
—
6
54
43
451
0.95
0.09
1.6
1.7
—
—
—
0
0
6
55
1.09
0.09
1.3
1.5
5.20
5.79
mmol/l
—
6
55
154
1508
1.02
0.08
2.1
1.7
1.40
1.42
%
0.14
147
1353
46
481
0.95
0.08
1.5
1.4
—
—
—
0
0
5
60
0.83
0.08
4.4
5.5
13.20
7.82
%
—
5
60
5
63
0.79
0.08
1.4
1.1
—
—
—
0
0
26
277
0.94
0.08
1.1
1.1
3.00
5.71
u/ml
1.05
16
144
5
65
0.77
0.08
1.0
1.7
—
—
—
0
0
58
559
1.04
0.08
1.3
1.4
207.96
235.99
miu/ml
0.29
24
281
8
75
1.07
0.07
1.4
1.6
—
—
—
0
0
7
80
0.87
0.07
1.1
1.4
139.77
189.06
pmol/l
—
7
80
8
93
0.86
0.06
2.1
1.6
0.53
0.48
e9/l
—
8
93
24
252
0.95
0.05
1.1
1.1
8.79
7.86
u/ml
0.07
13
118
10
109
0.92
0.04
1.8
1.3
—
—
—
0
0
10
109
0.92
0.04
1.8
1.3
—
—
—
0
0
118
1194
0.99
0.03
2.6
2.1
—
—
—
0
0
11
118
0.93
0.02
1.3
1.1
97.09
95.18
%
0.10
11
108
49
499
0.98
0.02
2.9
1.9
—
—
—
0
0
11
117
0.94
0.01
1.7
1.3
—
—
—
0
0
27
263
1.03
0.01
1.6
1.5
180.00
137.37
au/ml
—
7
83
14
134
1.05
0.00
1.1
1.7
—
—
—
0
0
232
2327
1.00
0.00
2.5
2.4
—
—
—
0
0
39
394
0.99
0.00
2.8
1.9
39.90
38.39
nmol/l
0.14
39
385
215
2153
1.00
0.00
2.4
2.3
—
—
—
0
0
12
123
0.98
0.00
3.6
3.1
6.73
7.34
mmol/l
0.52
12
117
12
123
0.98
0.00
4.8
4.3
38.42
301.96
u/ml
0.73
12
115
0
7
0.00
0.00
0.0
1.0
—
66.00
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
12.00
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
45.17
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
11
110
1.00
-0.00
1.7
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
59
1.02
-0.00
1.2
1.1
—
—
—
0
0
37
370
1.00
-0.00
1.4
1.6
83.84
58.38
ug/l
0.87
37
370
7
79
0.89
-0.00
1.3
1.1
—
45.60
—
0
5
5
52
0.96
-0.00
1.4
1.8
1.88
5.19
nmol/l
—
5
44
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
62
0.97
-0.00
2.8
3.4
7.07
10.17
mg/l
—
6
56
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_DEFORMITI_FEET and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_DEFORMITI_FEET | 1.245 [1.01, 1.53] | 0.039 |
| Birth year | 0.997 [0.99, 1.01] | 0.516 |
During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 5121 females with Q17_CONGEN_DEFORMITI_FEET died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_DEFORMITI_FEET | 1.2 [0.98, 1.48] | 0.085 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 5999 males with Q17_CONGEN_DEFORMITI_FEET died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_DEFORMITI_FEET.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.132% | 0.187% |
| 5 | 0.679% | 1.352% |
| 10 | 1.731% | 3.274% |
| 15 | 3.539% | 6.665% |
| 20 | 6.656% | 10.99% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_DEFORMITI_FEET – Congenital deformities of feet
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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