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Parapsoriasis

DOID EFO Endpoint Browser PheWeb

L12_PARAPSORI

parapsoriasis: one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis (red, scaly lesions), rather than by their underlying etiology. Neoplasms can develop from parapsoriasis. For example, it can develop into cutaneous T-cell lymphoma.

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L41
  • Cause of death: ICD-10 — L41

2 out of 7 registries used, show all original rules.

448

4. Check minimum number of events

None

448

5. Include endpoints

828

6. Filter based on genotype QC (FinnGen only)

740

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40-L45
Name in latin
Parapsoriasis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5761 2864 2860
Only index persons 5168 2640 2528
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 41.07 38.49 43.65
Only index persons 39.87 37.84 41.99

-FinnGen-

Key figures

All Female Male
Number of individuals 740 408 332
Unadjusted period prevalence (%) 0.15 0.14 0.15
Median age at first event (years) 48.30 42.17 55.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
769
Matched controls
7690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L42
ICD-10 Finland
Pityriasis rosea
284.0
307.7
286
16
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
12.4
228.9
278
335
L41.1
ICD-10 Finland
Pityriasis lichenoides chronica
+∞
156.8
145
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
39.6
116.6
72
20
L41.9
ICD-10 Finland
Parapsoriasis, unspecified
+∞
104.6
98
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.9
99.3
325
1000
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
34.8
95.4
61
19
D07AC01
ATC
betamethasone; topical
4.4
89.9
438
1789
E0000UV, ,
ATC
4.0
76.4
480
2263
D07AB08
ATC
desonide; topical
5.1
74.6
190
466
L41.3
ICD-10 Finland
Small plaque parapsoriasis
+∞
65.6
62
*
L41.8
ICD-10 Finland
Other parapsoriasis
+∞
62.3
59
*
L41.0
ICD-10 Finland
Pityriasis lichenoides et varioliformis acuta
+∞
54.9
52
*
D07AB02
ATC
hydrocortisone butyrate; topical
3.1
50.5
331
1501
E000001, ,
ATC
3.4
50.1
240
903
D05BB02
ATC
acitretin; oral
18.6
48.4
39
22
D05AX52
ATC
calcipotriol, combinations; topical
8.3
47.4
65
85
L41.2
ICD-10 Finland
Lymphomatoid papulosis
+∞
43.1
41
*
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
43.1
41
*
D07AC13
ATC
mometasone; topical
2.9
43.1
298
1369
D07AD01
ATC
clobetasol; topical
3.4
42.5
185
649
E000002, ,
ATC
3.7
41.2
150
468
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.3
37.1
79
162
XQ848
NOMESCO Finland
Dermatological photography
6.6
35.6
59
95
D05AX02
ATC
calcipotriol; topical
9.4
35.4
43
48
69630
ICD-8 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
32.5
31
*
C84.0
ICD-10 Finland
Mycosis fungoides
88.9
31.0
34
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.0
29.6
151
573
TQW80
NOMESCO Finland
Local dermatologic skincare
7.2
28.3
43
63
D07XC01
ATC
betamethasone; topical
3.3
27.5
116
393
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.3
25.4
108
367
D07AA02
ATC
hydrocortisone; topical
2.7
25.3
159
672
L43.8
ICD-10 Finland
Other lichen planus
64.5
22.0
25
*
H02AB06
ATC
prednisolone; systemic
2.1
21.0
390
2567
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.2
19.2
198
1036
D02AX
ATC
Other emollients and protectives
4.5
18.5
46
107
L04AX03
ATC
methotrexate; systemic
2.9
17.8
87
319
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.7
16.2
97
395
E000006, ,
ATC
3.1
14.6
65
225
L40.5
ICD-10 Finland
Arthropathic psoriasis
152.8
14.5
15
*
E000007, ,
ATC
3.1
13.8
61
211
69621
ICD-8 Finland
Psoriasis and similar disorders, Parapsoriasis guttata
+∞
13.6
13
*
E000003, ,
ATC
3.6
13.5
45
130
R06AX27
ATC
desloratadine; oral
1.9
13.4
243
1528
L40.9
ICD-10 Finland
Psoriasis, unspecified
15.4
13.1
21
14
D02AE01
ATC
carbamide; topical
2.9
12.8
61
220
ZXC50
NOMESCO Finland
Cryotherapy
4.1
12.5
34
85
D09AB01
ATC
zinc bandage without supplements; topical
5.9
12.3
22
38
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
38.2
12.2
15
*
L43.9
ICD-10 Finland
Lichen planus, unspecified
12.0
11.9
21
18
L04AD01
ATC
ciclosporin; systemic
6.0
11.8
21
36
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.3
11.8
46
147
R06AE07
ATC
cetirizine; oral
1.7
11.8
337
2401
L41
ICD-10 Finland
Parapsoriasis
+∞
11.5
11
*
9700/3-C44.9
ICD-O-3
Mycosis fungoides of skin, NOS
121.8
11.5
12
*
L30.0
ICD-10 Finland
Nummular dermatitis
3.3
11.1
43
137
D07BC01
ATC
betamethasone and antiseptics; topical
2.3
11.0
93
443
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
10.6
286
1994
XQ845
NOMESCO Finland
Dermatoscopy
4.7
10.5
24
52
L30.3
ICD-10 Finland
Infective dermatitis
3.3
9.7
36
112
L43.0
ICD-10 Finland
Hypertrophic lichen planus
55.7
9.7
11
*
J01FF01
ATC
clindamycin; systemic
1.7
9.5
204
1330
J01DB01
ATC
cefalexin; oral
1.8
9.4
627
5445
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
9.4
9
*
XQ800
NOMESCO Finland
Prick test
2.4
9.3
65
285
L20.0
ICD-10 Finland
Besnier prurigo
2.3
9.2
74
345
L40.4
ICD-10 Finland
Guttate psoriasis
37.2
9.0
11
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.9
8.8
26
69
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
8.7
398
3114
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
8.6
71
335
D01AC02
ATC
miconazole; topical
2.3
8.5
62
277
9700/3-C44.5
ICD-O-3
Mycosis fungoides of skin of trunk
91.0
8.4
9
*
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
8.3
8
*
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
8.3
8
*
6963A
ICD-9 Finland
Psoriasis and similar disorders, Pityriasis rosea
+∞
8.3
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
8.2
277
2012
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
17.4
8.1
12
7
D05AX03
ATC
calcitriol; topical
17.4
8.1
12
7
Z71.8
ICD-10 Finland
Other specified counselling
1.6
7.8
269
1958
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.6
203
1391
L40.8
ICD-10 Finland
Other psoriasis
25.3
7.6
10
*
J01DA01
ATC
[U] cefalexin
1.5
7.5
443
3618
ZXE00
NOMESCO Finland
One hour or less
1.5
7.4
278
2060
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
7.4
106
610
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.2
7.4
29
94
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
7.3
7
*
QXA05
NOMESCO Finland
Skin division, unspecified location
15.9
7.2
11
7
134
Kela drug reimbursment
General erythroderma
30.3
7.2
9
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.1
188
1282
S99
ICPC
Skin disease other
3.6
7.0
23
66
L04AA01
ATC
[U] ciclosporin
7.1
7.0
16
23
Z3231
NOMESCO Finland
Registered nurse
1.6
7.0
200
1391
M25.5
ICD-10 Finland
Pain in joint
1.5
6.9
244
1777
R51
ICD-10 Finland
Headache
2.3
6.9
50
223
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.7
6.8
21
58
L57.0
ICD-10 Finland
Actinic keratosis
2.0
6.7
78
419
XF404
NOMESCO Finland
Ambulatory ECG
2.1
6.7
66
334
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
6.7
67
341
D07AB01
ATC
clobetasone; topical
3.1
6.7
27
89
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.9
6.6
19
50
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.2
6.5
54
256
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
6.4
260
1945
L26
ICD-10 Finland
Exfoliative dermatitis
70.4
6.4
7
*
R03AC03
ATC
terbutaline; inhalant
1.8
6.4
97
568
XQ802
NOMESCO Finland
Epicutan test
2.6
6.3
34
132
69623
ICD-8 Finland
Psoriasis and similar disorders, Parapsoriasis varioliformis
+∞
6.3
6
*
S21
ICPC
Skin texture symptom/complaint
1.7
6.2
113
698
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
4.2
6.1
16
39
E000004, ,
ATC
3.5
6.0
20
58

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
256
8.06
108.65
1.7
1.3
—
—
—
0
0
347
2208
2.04
20.30
8.8
5.9
—
—
—
0
0
492
3554
2.07
20.12
9.7
6.2
0.21
0.19
e9/l
1.22
451
3125
487
3516
2.05
19.80
9.6
5.9
1.95
1.93
e9/l
0.18
450
3127
477
3442
2.02
19.12
9.6
5.9
0.04
0.04
e9/l
1.70
437
2967
476
3436
2.01
19.01
9.5
5.9
0.60
0.57
e9/l
1.73
437
2961
514
3839
2.02
18.30
11.8
9.2
4.19
4.09
e9/l
0.47
471
3347
456
3268
1.97
18.29
10.0
6.0
28.78
28.12
%
0.63
442
3113
446
3179
1.96
18.10
10.0
6.0
8.75
8.79
%
0.11
427
2994
448
3204
1.95
17.94
9.8
5.9
56.52
56.96
%
0.32
434
3072
443
3167
1.94
17.64
10.1
6.0
0.73
0.68
%
1.08
424
2973
443
3172
1.94
17.50
10.0
5.9
2.95
2.87
%
0.27
424
2981
412
3006
1.80
14.09
13.8
10.7
0.00
0.00
e9/l
0.27
346
2461
552
4573
1.73
10.46
5.2
4.3
—
3.26
—
0
8
105
545
2.07
9.95
6.4
4.5
0.41
0.59
%
0.53
28
166
104
542
2.06
9.74
1.6
1.4
—
—
—
0
0
19
21
9.25
9.56
1.9
2.9
0.23
0.20
e9/l
—
12
9
583
4957
1.73
9.45
9.1
8.0
79.20
78.34
u/l
0.18
566
4713
21
45
4.77
9.34
1.7
2.0
43.17
39.66
%
0.40
21
45
224
1507
1.69
9.25
1.6
1.5
2.48
2.37
g/l
0.38
149
950
133
769
1.88
9.22
1.7
1.6
—
—
—
0
0
198
1300
1.70
8.91
3.5
2.8
542.46
538.64
mosm/kgh2o
0.09
169
1137
101
539
2.01
8.85
7.2
4.7
0.04
0.13
%
1.07
25
149
23
57
4.13
8.57
1.8
2.3
1509.41
1283.12
e6/l
0.28
17
49
104
567
1.96
8.57
7.5
4.6
0.75
0.99
%
0.53
28
179
241
1680
1.63
8.56
1.4
1.4
1.10
1.41
u/ml
0.38
72
449
102
553
1.97
8.54
7.9
4.9
0.18
0.10
%
0.17
22
137
229
1582
1.64
8.41
5.9
4.4
—
—
—
0
0
338
2576
1.56
8.12
2.5
2.1
—
—
—
0
0
22
55
4.09
8.11
2.1
1.2
—
—
—
0
0
362
2816
1.54
7.84
5.7
5.2
35.97
36.02
g/l
0.06
345
2674
152
962
1.72
7.71
1.5
1.4
449.41
480.00
titre
0.12
34
199
99
553
1.91
7.58
2.6
2.7
71.09
70.84
e9/l
0.02
70
409
129
798
1.74
7.07
1.5
1.5
—
—
—
0
0
86
472
1.93
6.93
1.7
1.3
516.94
251.59
u/ml
0.59
78
439
184
1259
1.61
6.84
1.4
1.3
19.85
33.30
iu/ml
1.67
50
380
277
2095
1.50
6.53
2.3
2.6
69.58
63.00
u/l
0.27
258
1960
666
6057
1.74
6.44
6.1
5.2
1.82
1.88
mu/l
0.70
630
5642
176
1209
1.59
6.40
4.2
3.9
165.00
424.58
ng/l
1.54
122
893
420
3460
1.47
6.40
6.1
6.6
11.02
11.35
umol/l
0.38
402
3306
91
523
1.84
6.37
2.3
3.3
67.01
66.83
g/l
0.08
86
489
22
66
3.40
6.31
1.6
1.3
—
—
—
0
0
435
3619
1.47
6.23
4.5
3.7
0.04
0.42
estimate
0.45
98
732
432
3590
1.46
6.21
4.4
3.7
0.00
4.54
estimate
0.80
101
771
225
1647
1.52
6.13
3.3
2.8
334.63
344.05
umol/l
0.75
199
1478
207
1492
1.53
6.05
3.1
2.6
4.03
6.14
e6/l
1.86
180
1354
319
2511
1.46
6.04
4.7
3.9
155.58
70.66
e6/l
0.57
237
1750
427
3556
1.45
5.98
4.4
3.7
0.00
0.00
estimate
0.50
98
758
167
1150
1.58
5.97
1.3
1.3
8.56
12.19
u/ml
0.42
74
431
18
49
3.74
5.95
1.7
2.3
910.83
497.98
e6/l
0.72
12
40
116
731
1.69
5.91
3.0
2.8
1.72
1.80
%
0.44
105
664
137
904
1.63
5.84
2.6
2.6
120.41
112.26
ug/g
0.13
106
718
366
2970
1.44
5.83
2.7
2.5
78.56
75.94
nmol/l
0.97
345
2708
258
1961
1.48
5.79
2.3
2.1
185.45
284.08
u/l
0.89
250
1866
260
1993
1.46
5.54
7.3
5.9
—
—
—
0
0
75
425
1.85
5.50
1.9
2.8
—
—
—
0
0
49
240
2.11
5.43
1.7
1.2
—
—
—
0
0
696
6474
1.79
5.37
20.1
15.1
21.32
23.34
mg/l
0.95
591
5300
243
1849
1.46
5.35
3.8
3.2
0.28
0.44
e6/l
0.82
189
1358
23
79
2.97
5.34
2.0
2.2
0.81
0.95
%
0.77
12
51
37
165
2.31
5.15
3.2
3.2
5.38
2.37
index
0.37
24
98
124
823
1.60
5.14
3.4
3.0
4.01
5.10
e9/l
0.90
111
733
17
50
3.45
5.05
1.5
2.5
282.50
230.23
e6/l
0.27
12
43
387
3227
1.40
5.03
7.6
7.2
1.22
1.21
mmol/l
1.54
343
2806
275
2164
1.42
4.98
4.0
3.3
50.09
87.31
e6/l
0.53
222
1658
611
5537
1.50
4.92
25.2
18.5
13.60
13.54
%
0.60
605
5482
53
278
1.97
4.91
3.2
1.8
12.16
6.99
iu/ml
0.43
14
62
49
250
2.03
4.90
1.9
1.6
11.18
11.70
u/ml
0.04
13
53
30
125
2.46
4.86
1.2
1.1
19.82
15.48
au/ml
—
5
42
719
6785
1.92
4.85
15.2
11.3
25.80
26.27
u/l
0.37
706
6622
202
1518
1.45
4.65
2.2
1.8
1.27
1.21
mg/l
0.07
164
1173
571
5134
1.44
4.55
4.9
4.3
14.92
14.68
pmol/l
1.52
536
4733
257
2025
1.40
4.53
3.7
3.1
0.07
0.06
estimate
0.05
90
625
333
2740
1.38
4.53
4.2
3.5
0.09
0.03
estimate
0.54
88
636
697
6537
1.71
4.53
21.8
17.5
139.38
139.66
mmol/l
2.24
692
6424
350
2907
1.37
4.48
20.2
13.2
1.30
1.22
inr
1.70
302
2416
14
32
4.44
4.45
2.2
3.0
541.07
843.78
u/ml
0.88
14
32
151
1087
1.48
4.31
3.7
3.4
0.80
0.82
mmol/l
0.90
144
1043
226
1755
1.41
4.30
3.8
3.2
—
0.00
estimate
—
0
8
228
1774
1.41
4.29
4.4
4.3
—
—
—
0
0
250
1987
1.38
4.12
3.7
3.0
—
—
—
0
0
444
3861
1.35
4.10
6.1
5.1
6.58
6.63
mmol/l
0.18
423
3624
16
53
3.06
3.98
1.1
1.1
—
—
—
0
0
87
565
1.61
3.95
1.3
1.5
—
—
—
0
0
694
6548
1.61
3.82
22.2
17.6
3.95
3.96
mmol/l
0.57
688
6417
221
1740
1.38
3.81
2.5
2.2
2.55
2.84
mg/l
1.23
196
1506
342
2880
1.34
3.81
3.6
3.4
6.18
6.20
ph
0.09
179
1649
136
982
1.47
3.81
2.7
2.2
29.27
29.37
s
0.07
136
956
295
2431
1.35
3.80
4.1
3.7
34.47
53.29
ng/l
0.61
198
1685
260
2104
1.36
3.77
4.3
4.1
7.74
8.73
mg/mmol
0.14
165
1350
150
1110
1.44
3.69
2.5
2.4
13.50
13.30
umol/l
0.13
144
1039
129
928
1.47
3.68
2.2
2.1
—
—
—
0
0
170
1289
1.41
3.65
3.5
2.8
2.45
2.45
mmol/l
0.28
154
1159
14
40
3.55
3.62
2.9
3.9
0.64
0.85
index
0.70
14
40
240
1929
1.35
3.61
4.5
4.1
7.40
7.40
ph
0.36
172
1378
276
2268
1.34
3.58
3.9
3.4
7.28
7.95
mmol/l
1.77
241
1941
341
2896
1.32
3.49
6.9
6.5
1.21
1.21
mmol/l
0.30
322
2688
47
267
1.81
3.48
1.4
1.2
0.22
2.76
u/ml
—
5
10
209
1653
1.36
3.47
4.5
4.1
88.69
90.32
%
0.37
203
1622
16
58
2.80
3.44
1.1
1.1
—
—
—
0
0
136
1005
1.43
3.36
1.6
1.7
1151.50
1189.38
nmol/l
0.23
103
776
122
888
1.44
3.27
1.2
1.2
—
—
—
0
0
270
2240
1.32
3.20
4.0
3.4
2.35
2.35
mmol/l
0.09
248
2058
193
1525
1.35
3.19
2.0
2.1
—
—
—
0
0
70
456
1.59
3.16
3.4
4.3
81.58
79.88
ng/l
0.07
61
410
384
3346
1.29
3.14
3.4
3.1
116.26
113.58
ug/l
0.09
373
3153
71
467
1.57
3.09
2.7
2.5
25.73
19.91
au/ml
—
9
46
249
2056
1.31
3.03
3.6
3.5
42.39
51.07
mg/l
0.27
167
1358
94
661
1.48
3.01
2.8
2.1
310.16
386.78
nmol/l
3.47
88
625
653
6144
1.42
3.00
5.0
4.9
5.85
5.90
mmol/l
0.57
613
5696
97
689
1.47
2.96
3.3
4.1
7.39
7.38
ph
0.12
57
389
20
89
2.28
2.89
2.0
2.5
—
—
—
0
0
7
13
5.42
2.87
1.0
1.1
0.07
1.39
u/ml
—
7
13
45
270
1.71
2.81
1.7
2.1
1.49
1.49
g/l
0.01
40
244
66
437
1.56
2.81
2.8
2.9
185.32
161.79
ng/l
0.19
58
401
164
1289
1.35
2.79
1.6
1.7
—
—
—
0
0
119
888
1.40
2.78
1.5
1.6
—
—
—
0
0
118
882
1.40
2.74
4.5
5.9
1.00
1.04
mmol/l
1.28
106
821
221
1828
1.29
2.60
3.2
3.2
1233.78
1264.77
ng/l
0.05
183
1568
7
15
4.70
2.60
1.4
1.3
11.94
9.90
mmol/l
—
7
15
22
107
2.09
2.59
1.5
1.2
—
—
—
0
0
732
7082
1.70
2.59
30.7
22.9
6.97
6.74
e9/l
2.14
724
6940
108
805
1.40
2.55
1.5
1.8
—
—
—
0
0
22
108
2.07
2.54
1.1
1.1
4.51
2.05
eliau/ml
—
7
46
138
1074
1.35
2.50
3.3
3.1
3.54
2.21
e6/l
0.56
84
533
101
747
1.41
2.49
1.4
1.3
—
—
—
0
0
731
7076
1.67
2.49
30.7
22.9
255.10
250.83
e9/l
0.95
723
6958
21
102
2.09
2.49
4.0
3.5
4.35
4.45
e9/l
0.05
21
102
325
2831
1.26
2.48
2.4
2.1
96.54
96.33
pmol/l
0.03
196
1525
731
7079
1.66
2.45
30.6
22.8
4.49
4.51
e12/l
0.52
724
6944
91
664
1.42
2.43
3.4
4.1
1.49
1.83
mmol/l
0.36
78
567
22
110
2.03
2.43
1.4
1.4
62.12
59.82
mmol/l
0.08
16
97
632
5967
1.33
2.41
6.6
6.1
38.89
38.95
mmol/mol
0.06
609
5655
81
580
1.44
2.39
1.2
1.2
—
—
—
0
0
235
1977
1.27
2.39
4.6
3.8
0.00
0.01
estimate
1.34
95
718
10
33
3.06
2.36
1.0
1.1
105.43
196.99
iu/ml
—
10
33
662
6298
1.37
2.36
4.9
4.8
1.45
1.45
mmol/l
0.04
617
5892
664
6321
1.37
2.35
5.2
4.9
4.57
4.61
mmol/l
0.48
627
5954
671
6400
1.38
2.33
5.8
5.5
2.69
2.71
mmol/l
0.23
634
6003
13
53
2.48
2.28
1.3
1.2
0.99
1.74
u/ml
—
8
32
27
150
1.83
2.23
3.2
4.2
—
—
—
0
0
21
108
1.97
2.17
1.2
1.2
—
—
—
0
0
697
6705
1.42
2.16
17.0
13.4
—
—
—
0
0
265
2295
1.24
2.05
3.5
3.3
29.20
32.85
u/l
1.66
254
2196
6
15
4.02
2.04
1.2
1.1
—
—
—
0
0
9
32
2.83
2.00
1.4
1.4
6.13
6.31
mmol/l
—
9
32
488
4510
1.22
1.97
3.5
3.3
45.56
44.94
u/l
0.07
465
4286
32
195
1.67
1.96
1.2
1.2
—
—
—
0
0
5
11
4.57
1.94
1.0
1.0
4.00
4.08
u/ml
—
5
11
308
2723
1.22
1.93
2.1
1.9
1.35
1.34
mmol/l
0.09
274
2320
189
1593
1.25
1.85
4.4
3.8
1.02
1.02
kg/l
1.07
120
1059
62
446
1.42
1.83
1.4
1.2
—
—
—
0
0
14
66
2.14
1.83
1.0
1.1
33.68
18.29
u/ml
—
5
33
31
193
1.63
1.77
2.4
2.2
12.46
11.83
mg/l
0.14
25
182
43
290
1.51
1.76
2.9
2.3
—
—
—
0
0
28
171
1.66
1.72
1.8
1.6
6134.43
9041.14
e6/l
0.41
21
123
108
858
1.30
1.72
1.4
1.3
—
—
—
0
0
5
13
3.86
1.71
2.2
1.8
34.60
29.85
%
—
5
13
51
361
1.44
1.66
1.4
1.2
—
—
—
0
0
5
14
3.59
1.61
1.8
2.1
—
—
—
0
0
41
280
1.49
1.60
1.2
1.4
315.00
245.88
miu/ml
0.40
18
140
17
92
1.87
1.57
1.3
1.4
—
—
—
0
0
17
92
1.87
1.57
1.3
1.4
—
—
—
0
0
17
92
1.87
1.57
1.3
1.4
—
—
—
0
0
17
92
1.87
1.57
1.3
1.4
—
—
—
0
0
29
184
1.60
1.56
1.2
1.2
—
—
—
0
0
137
1138
1.25
1.53
3.1
3.0
0.78
1.01
e6/l
0.52
83
595
23
138
1.69
1.53
1.3
1.4
114.17
142.67
au/ml
—
6
41
24
146
1.66
1.52
3.8
3.2
58.08
58.86
%
0.09
24
146
17
94
1.83
1.48
1.0
1.2
—
—
—
0
0
16
87
1.86
1.46
1.3
1.3
—
—
—
0
0
91
724
1.29
1.45
9.1
8.4
7.42
7.42
ph
0.23
46
416
625
5993
1.23
1.44
4.3
4.1
1.30
1.27
mmol/l
0.52
575
5568
80
626
1.31
1.44
2.4
2.4
0.22
0.21
g/l
0.04
73
589
68
521
1.33
1.42
2.9
2.2
6.00
6.15
ph
0.71
37
348
106
863
1.26
1.41
1.6
1.5
—
—
—
0
0
15
81
1.87
1.41
2.1
1.3
467.40
342.17
mu/l
—
10
65
233
2062
1.19
1.37
5.7
5.4
1.73
2.42
ug/l
2.17
209
1862
6
23
2.62
1.37
3.7
2.4
—
—
—
0
0
71
551
1.32
1.36
4.9
3.6
—
—
—
0
0
20
120
1.68
1.35
4.9
3.1
—
—
—
0
0
29
192
1.53
1.34
1.4
1.1
—
—
—
0
0
48
353
1.38
1.31
2.0
3.0
0.67
0.61
%
0.38
48
353
6
24
2.51
1.30
1.2
1.4
—
—
—
0
0
63
485
1.33
1.29
2.7
4.0
1.23
1.23
mmol/l
0.08
55
418
15
84
1.80
1.27
2.7
2.8
—
—
—
0
0
8
35
2.30
1.27
1.0
1.1
1116.16
1454.26
miu/ml
—
8
35
8
36
2.23
1.24
1.1
1.1
—
—
—
0
0
28
189
1.50
1.20
1.3
1.4
237.69
294.01
ug/g
0.87
13
107
145
1245
1.20
1.19
3.3
3.1
0.61
0.77
ug/l
2.39
87
795
23
149
1.56
1.18
1.3
1.4
—
—
—
0
0
11
57
1.94
1.17
1.5
1.4
—
—
—
0
0
24
158
1.54
1.16
1.5
1.3
229.62
238.24
u/ml
0.07
16
80
22
142
1.57
1.15
1.1
1.5
—
—
—
0
0
88
720
1.25
1.15
9.4
8.3
0.96
0.93
mmol/l
0.03
73
598
5
20
2.51
1.15
2.2
2.1
0.59
0.61
mmol/l
—
5
20
39
284
1.39
1.15
1.1
1.1
—
—
—
0
0
215
1919
1.17
1.13
1.8
1.7
20.56
20.19
nmol/l
0.14
189
1634
62
487
1.30
1.12
2.3
2.5
6.46
7.20
ug/l
0.13
52
438
151
1311
1.19
1.11
1.9
1.7
465.91
24687366.73
pmol/l
1.18
131
1118
17
104
1.65
1.10
3.5
3.2
0.67
0.87
nmol/l
1.09
12
84
11
59
1.88
1.07
1.4
1.7
—
—
—
0
0
25
171
1.48
1.03
1.1
1.2
—
—
—
0
0
242
2194
1.15
1.03
3.3
2.4
—
—
—
0
0
14
83
1.70
1.02
2.2
1.3
19.21
27.13
ng/l
0.70
14
83
13
76
1.72
0.99
1.9
2.7
3.94
4.03
mmol/l
0.42
13
76
13
76
1.72
0.99
1.9
2.7
105.92
105.39
mmol/l
0.18
13
76
7
36
1.95
0.97
1.1
2.0
—
—
—
0
0
12
69
1.75
0.97
1.0
1.8
—
—
—
0
0
40
303
1.34
0.96
3.6
3.2
1.02
1.02
ratio
0.67
40
284
93
784
1.21
0.95
3.6
3.1
7.05
8.21
umol/l
0.32
76
696
6
27
2.23
0.93
3.7
2.2
—
—
—
0
0
73
601
1.24
0.93
2.2
2.0
0.00
0.02
estimate
0.50
21
134
77
638
1.23
0.93
2.6
2.7
42.17
109.12
u/l
0.41
63
532
6
28
2.15
0.91
1.2
1.7
1.27
0.95
nmol/l
—
6
19
6
28
2.15
0.91
3.0
2.3
41.50
83.31
ug/l
—
6
28
340
3178
1.13
0.88
3.2
2.8
—
—
estimate
—
0
0
181
1625
1.15
0.88
2.9
2.3
—
—
—
0
0
8
43
1.87
0.87
1.0
1.1
1.14
1.06
ratio
—
8
37
39
300
1.32
0.86
3.3
3.2
24.95
25.14
mmol/l
0.16
39
288
32
239
1.35
0.85
1.9
1.9
—
—
—
0
0
12
72
1.68
0.85
1.3
1.4
—
—
nmol/l
—
0
0
235
2154
1.13
0.84
3.7
3.5
—
0.83
—
0
6
8
46
1.75
0.82
1.0
1.0
—
—
—
0
0
12
74
1.63
0.78
2.0
2.7
1.20
1.19
mmol/l
0.11
12
74
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
16
108
1.49
0.74
1.6
1.8
—
—
—
0
0
10
60
1.68
0.72
1.5
1.4
—
—
—
0
0
36
283
1.29
0.71
1.6
1.7
309.77
283.59
mu/l
0.31
31
262
52
428
1.23
0.70
2.9
3.4
138.33
130.34
g/l
2.14
52
418
103
904
1.16
0.70
1.7
1.8
—
—
—
0
0
25
187
1.35
0.69
1.1
1.5
599.40
476.88
mg/l
0.56
25
177
12
77
1.57
0.69
1.7
2.8
0.69
1.22
g/24h
—
6
48
26
197
1.33
0.66
2.3
2.1
2.04
4.67
iu/l
—
7
80
12
78
1.55
0.66
1.2
1.2
—
—
—
0
0
7
44
1.60
0.65
1.3
1.0
—
—
—
0
0
69
590
1.19
0.65
11.8
8.7
—
—
—
0
0
19
138
1.39
0.63
1.2
1.1
—
—
—
0
0
19
138
1.39
0.63
1.1
1.8
—
—
—
0
0
18
130
1.39
0.61
1.2
1.1
—
—
—
0
0
5
30
1.67
0.61
5.0
2.7
11.10
16.37
ug/l
—
5
25
0
22
0.00
0.59
0.0
4.0
—
6.59
—
0
22
8
53
1.51
0.58
1.4
1.3
—
—
—
0
0
6
35
1.72
0.57
1.0
2.1
2.40
1.99
umol/l
—
6
30
8
54
1.49
0.57
1.0
1.0
—
—
—
0
0
6
36
1.67
0.56
1.0
1.3
136.33
141.84
nmol/l
—
6
36
6
36
1.67
0.56
1.2
1.6
—
—
—
0
0
6
36
1.67
0.56
1.2
1.5
100.02
72.42
ng/l
—
6
36
8
55
1.46
0.56
1.0
1.1
26.50
42.53
mg/l
—
8
43
9
60
1.51
0.54
1.0
1.1
—
—
—
0
0
15
108
1.40
0.53
1.4
1.3
4.38
4.26
u/ml
—
8
46
6
39
1.54
0.53
1.5
1.3
—
—
—
0
0
6
40
1.50
0.51
1.3
3.7
14.27
16.24
%
—
6
40
9
64
1.41
0.51
1.8
3.2
48.50
58.51
%
—
9
59
40
334
1.21
0.51
2.3
2.1
0.00
2.30
estimate
0.50
18
109
9
65
1.39
0.50
1.0
1.2
—
—
—
0
0
41
344
1.20
0.50
2.7
2.2
17781.88
6164.24
u/l
0.60
18
149
7
109
0.64
0.48
1.0
2.3
—
10.80
—
0
5
7
46
1.53
0.48
1.1
1.2
—
—
—
0
0
30
245
1.23
0.47
4.5
1.8
—
—
—
0
0
73
651
1.13
0.44
2.7
4.5
90.81
28.70
ug/l
0.37
56
541
5
32
1.57
0.42
1.6
1.3
—
—
—
0
0
8
58
1.38
0.41
1.3
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
61.35
—
0
17
19
150
1.27
0.40
2.6
1.6
—
—
—
0
0
28
233
1.21
0.39
1.5
1.5
7.79
8.99
u/l
0.30
23
186
15
115
1.31
0.39
1.6
1.6
—
—
—
0
0
9
67
1.35
0.38
2.0
1.6
87.86
90.60
%
—
9
67
33
281
1.18
0.37
1.7
1.3
—
—
—
0
0
16
126
1.28
0.35
3.6
2.8
6.00
8.48
pmol/l
1.50
16
126
6
43
1.40
0.35
1.3
1.4
110.00
75.33
umol/l
—
6
43
28
328
0.85
0.33
2.3
1.7
0.27
0.31
mg/l
0.25
19
152
10
132
0.75
0.32
2.6
4.2
12.20
24.14
mg/l
—
5
97
14
110
1.28
0.32
1.4
1.3
1.91
3.26
ug/l
1.46
14
98
7
54
1.30
0.30
1.0
1.1
158.14
228.65
mg/l
—
7
46
76
699
1.10
0.29
1.5
1.4
—
—
—
0
0
33
288
1.15
0.29
1.7
1.8
—
—
—
0
0
65
595
1.10
0.28
2.5
2.4
12.72
12.97
nmol/l
0.08
59
546
9
118
0.76
0.27
1.7
1.9
—
—
—
0
0
5
72
0.69
0.26
5.6
5.9
7.28
7.08
mmol/l
—
5
56
272
2633
1.05
0.26
2.7
3.0
—
—
—
0
0
9
77
1.17
0.24
1.7
1.2
—
—
—
0
0
10
78
1.29
0.24
2.1
2.4
—
—
—
0
0
31
347
0.89
0.22
2.2
1.5
—
—
—
0
0
61
565
1.09
0.22
3.9
4.1
7.30
7.35
ph
0.54
43
411
0
11
0.00
0.21
0.0
1.3
—
1.72
—
0
11
0
10
0.00
0.21
0.0
1.0
—
0.18
—
0
5
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
8
102
0.78
0.21
1.1
1.1
1.51
1.48
g/l
—
8
94
6
48
1.25
0.20
1.2
3.3
6.97
8.41
mmol/l
—
6
48
33
364
0.90
0.19
1.1
1.1
—
—
—
0
0
6
51
1.18
0.19
1.0
1.4
—
—
—
0
0
10
81
1.24
0.19
1.5
2.0
13.06
13.24
%
—
10
81
10
81
1.24
0.19
2.6
2.2
—
—
—
0
0
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
7
60
1.17
0.18
1.3
1.1
1.06
1.58
nmol/l
—
7
55
32
351
0.91
0.17
2.6
1.5
—
—
—
0
0
23
257
0.89
0.17
1.1
1.1
0.83
0.89
g/l
0.90
23
257
5
68
0.73
0.17
1.6
3.5
—
—
—
0
0
32
350
0.91
0.16
2.2
1.5
—
—
—
0
0
15
172
0.87
0.16
1.1
1.1
1.37
3.30
u/ml
—
10
97
30
328
0.91
0.15
2.9
3.9
—
—
—
0
0
9
78
1.16
0.15
1.1
1.8
—
—
—
0
0
9
83
1.09
0.14
1.2
1.1
—
—
—
0
0
32
347
0.92
0.14
2.2
1.5
—
—
—
0
0
14
159
0.88
0.13
1.4
1.3
—
—
—
0
0
53
503
1.06
0.12
1.2
1.3
138.76
154.64
u/ml
0.11
25
210
21
191
1.10
0.12
2.3
4.2
1.60
2.67
ratio
1.11
11
113
205
2093
0.97
0.11
1.5
1.5
—
—
—
0
0
23
250
0.92
0.11
1.1
1.1
1.53
1.53
g/l
0.04
23
250
15
167
0.90
0.11
1.0
1.1
—
—
—
0
0
23
212
1.09
0.10
2.2
4.5
37.55
41.07
mg/l
0.13
17
186
23
212
1.09
0.10
2.3
4.5
65.80
78.85
mg/l
0.17
17
183
5
44
1.14
0.10
1.0
1.2
0.81
0.55
ratio
—
5
27
7
64
1.09
0.08
1.0
4.9
11.83
11.33
%
—
7
64
7
68
1.03
0.08
2.1
2.6
—
—
—
0
0
6
73
0.82
0.07
2.2
2.4
—
—
—
0
0
48
461
1.04
0.07
1.5
1.6
1199.80
938.46
mu/l
0.98
43
395
7
84
0.83
0.07
1.0
1.3
—
—
—
0
0
27
255
1.06
0.07
5.0
3.7
233.63
267.46
mg/l
0.13
16
119
11
122
0.90
0.07
1.0
1.2
—
—
—
0
0
9
102
0.88
0.06
5.2
6.0
11.09
11.56
mg/l
—
9
94
37
357
1.04
0.04
1.6
1.7
—
—
—
0
0
19
201
0.94
0.04
10.5
10.3
—
—
—
0
0
61
596
1.03
0.04
1.6
1.7
3.34
3.44
mmol/l
0.30
43
420
23
237
0.97
0.01
1.1
1.1
0.54
0.72
ratio
—
5
23
14
134
1.05
0.00
1.1
1.1
—
—
—
0
0
13
125
1.04
0.00
1.5
1.7
—
—
—
0
0
14
135
1.04
0.00
1.1
1.1
—
—
—
0
0
25
245
1.02
0.00
3.4
2.8
—
—
—
0
0
26
255
1.02
0.00
2.3
3.5
87.33
1833.00
u/ml
1.61
21
219
20
196
1.02
0.00
1.5
1.5
—
—
—
0
0
32
324
0.99
0.00
2.2
1.5
—
—
—
0
0
67
675
0.99
0.00
1.3
1.3
—
—
—
0
0
15
151
0.99
0.00
2.5
3.5
30.53
33.96
umol/l
0.23
15
138
20
201
0.99
0.00
1.5
1.6
—
—
—
0
0
23
229
1.00
0.00
1.7
1.8
48.43
40.28
nmol/l
0.44
23
218
28
279
1.00
0.00
2.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
41.75
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
82
0.98
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
189.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint L12_PARAPSORI and mortality.

Females

Parameter HR [95% CI] p-value
L12_PARAPSORI 1.115 [0.94, 1.32] 0.2
Birth year 0.997 [0.99, 1.01] 0.585

During the follow-up period (1.1.1998 — 31.12.2019), 221 out of 2204 females with L12_PARAPSORI died.

Males

Parameter HR [95% CI] p-value
L12_PARAPSORI 0.996 [0.87, 1.14] 0.949
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 2069 males with L12_PARAPSORI died.

Mortality risk

Mortality risk for people of age

years, who have L12_PARAPSORI.

N-year risk Females Males
1 0.097% 0.203%
5 0.617% 1.12%
10 1.461% 2.943%
15 2.779% 5.843%
20 5.352% 10.016%

Relationships between endpoints

↥

Index endpoint: L12_PARAPSORI – Parapsoriasis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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