Listeriosis

AB1_LISTERIOSIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A32
  • Hospital discharge: ICD-9 027[0]
  • Hospital discharge: ICD-8 027[0]
  • Cause of death: ICD-10 A32
  • Cause of death: ICD-9 027[0]
  • Cause of death: ICD-8 027[0]

2 out of 7 registries used, show all original rules.

206

4. Check minimum number of events

None

206

5. Include endpoints

None

206

6. Filter based on genotype QC (FinnGen only)

180

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1333 676 639
Only index persons 984 554 430
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 69.92 69.30 70.68
Only index persons 70.94 69.41 72.91

-FinnGen-

Key figures

All Female Male
Number of individuals 180 93 87
Unadjusted period prevalence (%) 0.04 0.03 0.04
Median age at first event (years) 69.95 66.33 73.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
183
Matched controls
1830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A32.7
ICD-10 Finland
Listerial sepsis
+∞
156.6
127
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
61.7
101.9
59
14
R50.9
ICD-10 Finland
Fever, unspecified
7.3
34.7
67
135
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
31.1
29
*
G01*A32.1
ICD-10 Finland
Listerial meningitis
+∞
25.6
24
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.8
24.2
28
30
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
19.8
63
189
L04AX01
ATC
azathioprine; systemic
16.2
18.0
29
21
A46
ICD-10 Finland
Erysipelas
6.5
17.1
31
56
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
16.9
16
*
TK800
NOMESCO Finland
Hemodialysis
35.1
15.1
19
6
WX892
NOMESCO Finland
Monitored bed care
6.0
14.9
29
56
A41.8
ICD-10 Finland
Other specified sepsis
+∞
14.8
14
*
B03XA02
ATC
darbepoetin alfa; parenteral
21.4
14.6
21
11
ZX120
NOMESCO Finland
Intravenous
4.6
14.5
40
105
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
13.8
65
249
N17.9
ICD-10 Finland
Acute renal failure, unspecified
12.4
13.5
24
22
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.4
13.4
29
62
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
12.8
100
512
B01AA03
ATC
warfarin; systemic
3.3
12.8
66
266
A32.1
ICD-10 Finland
Listerial meningitis and meningoencephalitis
+∞
12.6
12
*
A32.8
ICD-10 Finland
Other forms of listeriosis
+∞
12.6
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
12.4
39
113
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
16.1
12.1
19
13
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.1
12.0
38
110
C03CA01
ATC
furosemide; systemic
3.0
11.9
97
503
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.7
11.6
23
45
H02AB06
ATC
prednisolone; systemic
3.0
11.6
112
635
L04AA06
ATC
mycophenolic acid; systemic
37.6
11.4
14
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
18.6
11.4
17
10
M05BA04
ATC
alendronic acid; oral
3.9
10.8
37
113
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
10.3
26
63
ZXD05
NOMESCO Finland
Urgent procedure
2.8
10.2
73
347
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.7
10.2
25
59
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
10.1
110
647
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
9.9
34
104
J01MA12
ATC
levofloxacin; systemic
3.1
9.7
52
210
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.1
9.6
21
45
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
13.4
9.6
16
13
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
9.5
9
*
0270X
ICD-9 Finland
Other zoonotic bacterial diseases, Listeriosis[LISTERIOSIS ALIA (EI SYNNYNNÄINEN)]
+∞
9.5
9
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
9.3
73
361
Z49.1
ICD-10 Finland
Extracorporeal dialysis
38.8
9.1
11
*
J01MA02
ATC
ciprofloxacin; systemic
2.6
9.1
95
540
A11CC03
ATC
alfacalcidol; systemic
11.6
9.0
16
15
UJF32
NOMESCO Finland
Coloscopy
2.6
8.5
66
322
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
8.5
55
245
N18.0
ICD-10 Finland
End-stage renal disease
94.2
8.5
9
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.9
8.5
50
212
N02AA05
ATC
oxycodone; systemic
2.7
8.2
55
249
B01AB05
ATC
enoxaparin; parenteral
2.5
8.1
77
414
JN4BD
NOMESCO Finland
Extensive body CT
3.5
8.0
31
102
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.1
8.0
16
19
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.2
8.0
35
125
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
7.9
50
219
R2110
NOMESCO Finland
Giving the first information
4.7
7.9
19
44
127
Kela drug reimbursment
Transplant complication
26.3
7.7
10
*
XW000
NOMESCO Finland
Bone marrow biopsy
6.5
7.6
19
32
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
4.5
7.5
19
46
I50.0
ICD-10 Finland
Congestive heart failure
3.3
7.4
30
102
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.5
7.3
27
86
A32.9
ICD-10 Finland
Listeriosis, unspecified
+∞
7.3
7
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
7.3
21
56
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.6
7.3
26
81
WX002
NOMESCO Finland
Sedation and analgesia
2.6
7.1
51
237
SPAT1229
SPAT
Assessment of need for aid
3.6
7.1
25
77
L01BA01
ATC
methotrexate; systemic
7.2
7.0
16
24
A03FA01
ATC
metoclopramide; systemic, rectal
2.5
6.9
53
254
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
41.6
6.8
8
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
7.9
6.5
14
19
L04AA01
ATC
[U] ciclosporin
15.0
6.5
10
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
6.5
69
383
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
6.3
6
*
L04AD02
ATC
tacrolimus; systemic
+∞
6.3
6
*
C03DA01
ATC
spironolactone; oral
2.7
6.1
37
157
A10AC01
ATC
insulin (human); parenteral
3.5
6.1
22
69
A10AB05
ATC
insulin aspart; parenteral
3.4
6.0
23
75

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
114
392
6.06
32.79
9.8
3.4
—
—
—
0
0
48
101
6.09
23.06
16.6
4.9
12.19
10.28
mmol/l
0.88
48
96
29
40
8.43
20.56
2.4
1.6
2.79
0.24
ug/l
1.86
29
29
46
113
5.10
18.35
10.1
3.1
0.91
0.45
%
0.88
32
29
48
123
4.93
18.20
9.7
3.1
1.15
0.81
%
0.47
33
36
60
199
4.00
16.08
3.8
1.8
—
—
—
0
0
44
116
4.68
15.98
9.9
3.2
0.03
0.14
%
0.60
29
29
125
676
3.68
15.57
16.2
5.6
0.54
0.69
%
2.59
120
625
45
124
4.49
15.42
9.4
3.5
2.77
0.43
%
0.41
30
28
124
678
3.57
14.95
16.5
5.5
2.02
2.86
%
5.43
119
629
124
685
3.51
14.55
16.3
5.7
24.25
27.16
%
1.40
119
645
123
677
3.49
14.50
16.7
5.8
8.99
8.96
%
0.03
118
630
57
203
3.63
13.52
4.5
2.5
2.17
1.70
%
0.99
52
179
121
697
3.17
12.49
13.9
3.9
32.10
35.71
g/l
7.32
115
653
48
160
3.71
12.48
1.8
1.9
—
—
—
0
0
46
150
3.76
12.35
5.3
2.4
87.71
66.21
e9/l
1.35
41
108
97
497
3.03
12.30
16.0
5.1
—
—
—
0
0
127
756
3.22
12.29
14.9
5.4
0.03
0.04
e9/l
1.60
111
635
126
751
3.18
12.08
14.9
5.4
0.90
0.59
e9/l
0.71
111
630
39
115
4.04
12.05
5.8
2.5
—
—
—
0
0
52
188
3.47
11.91
1.7
1.3
1088.00
602.86
titre
0.51
15
42
127
767
3.14
11.77
15.0
5.6
1.74
1.83
e9/l
0.22
113
662
127
784
3.03
10.99
15.4
5.8
0.17
0.18
e9/l
0.24
111
665
27
64
4.78
10.99
3.9
1.5
6.96
11.41
iu/ml
0.35
11
16
132
844
3.02
10.49
26.1
8.7
4.79
4.03
e9/l
1.66
121
726
23
54
4.73
9.43
8.5
4.4
5.03
4.31
ratio
0.09
16
28
81
429
2.59
8.93
3.5
2.1
3.97
3.06
mg/l
1.88
72
358
20
44
4.98
8.83
1.7
1.2
—
—
—
0
0
119
764
2.59
8.63
28.0
15.1
1.41
1.29
inr
1.45
109
618
24
65
4.10
8.21
5.0
2.8
—
—
—
0
0
33
117
3.22
7.59
2.2
1.4
—
—
—
0
0
13
14
9.90
6.91
16.9
2.9
—
—
—
0
0
36
143
2.89
6.79
2.2
1.4
—
—
—
0
0
42
188
2.60
6.28
2.1
1.5
—
—
—
0
0
86
527
2.19
6.28
4.3
3.3
—
—
—
0
0
121
856
2.22
6.05
22.0
5.8
1.19
1.22
mmol/l
4.48
108
738
88
554
2.13
5.90
5.5
3.2
68.22
159.95
e6/l
0.34
76
412
112
774
2.15
5.87
18.5
5.2
1.19
1.22
mmol/l
4.36
105
706
16
41
4.18
5.85
4.8
2.0
2.10
1.57
mg/l
1.09
16
33
11
13
8.92
5.64
1.1
1.1
—
—
—
0
0
12
17
7.47
5.53
1.9
1.5
—
—
—
0
0
32
133
2.70
5.51
15.2
7.0
—
—
—
0
0
14
25
5.97
5.50
1.5
1.8
—
—
—
0
0
40
186
2.47
5.49
21.0
6.7
7.42
7.42
ph
0.08
27
111
57
310
2.22
5.47
9.3
4.3
—
—
—
0
0
36
160
2.56
5.42
8.9
2.9
0.83
1.88
mmol/l
1.37
29
140
40
188
2.44
5.36
21.0
6.6
1.25
1.11
mmol/l
0.08
33
164
11
15
7.72
5.22
3.5
3.7
—
—
—
0
0
13
23
6.00
5.17
1.8
1.3
1202.00
1589.06
e6/l
—
6
18
22
77
3.11
5.13
1.5
1.4
—
—
—
0
0
10
12
8.74
5.13
1.3
1.6
—
—
—
0
0
13
24
5.74
5.02
1.5
1.3
—
—
—
0
0
12
20
6.34
5.00
3.9
2.2
13.29
16.10
%
1.72
12
20
80
511
2.00
4.94
5.7
2.3
—
—
—
0
0
92
620
1.97
4.85
6.6
3.9
158.83
86.67
e6/l
0.33
75
427
12
21
6.03
4.84
2.0
1.4
—
—
—
0
0
75
477
1.97
4.62
5.3
3.1
0.27
0.37
e6/l
0.48
64
337
11
19
6.09
4.51
3.1
2.0
—
—
—
0
0
20
72
3.00
4.45
1.5
1.4
—
—
—
0
0
38
189
2.28
4.45
2.0
1.3
—
—
—
0
0
94
654
1.90
4.37
6.3
4.1
94.13
48.80
ng/l
0.48
79
506
10
16
6.54
4.35
1.0
1.1
—
—
—
0
0
34
163
2.33
4.32
9.8
2.8
7.37
7.39
ph
0.83
25
98
23
94
2.65
4.07
8.3
2.8
23.00
24.43
mmol/l
2.18
23
94
99
712
1.85
4.05
6.2
2.6
—
—
estimate
—
0
0
14
37
4.01
3.99
5.3
1.3
—
—
—
0
0
42
228
2.09
3.94
13.5
5.8
104.60
103.93
mmol/l
0.37
42
228
10
19
5.50
3.88
1.5
1.4
6.20
6.05
mmol/l
—
10
19
9
15
6.25
3.86
2.9
1.4
1.97
1.50
mmol/l
—
9
15
7
8
9.04
3.80
1.9
1.1
—
—
—
0
0
11
25
4.61
3.69
5.4
2.0
—
—
—
0
0
23
99
2.51
3.68
23.7
3.8
—
—
—
0
0
13
35
3.92
3.67
1.2
1.0
—
—
—
0
0
7
9
8.03
3.59
2.3
1.0
—
—
—
0
0
33
169
2.16
3.58
5.8
2.0
628.08
93.55
ug/g
1.36
25
135
6
6
10.28
3.52
1.0
1.3
—
—
—
0
0
33
171
2.13
3.47
2.4
1.6
—
—
—
0
0
23
102
2.44
3.46
14.1
8.0
92.96
93.22
%
0.05
23
102
21
90
2.51
3.39
1.1
1.4
—
55.06
—
0
8
27
130
2.26
3.39
1.7
1.4
—
—
—
0
0
50
306
1.87
3.30
2.4
1.7
1048.49
1149.16
nmol/l
0.37
41
224
9
19
4.92
3.28
1.7
1.2
—
—
—
0
0
10
24
4.34
3.24
1.9
1.9
—
—
—
0
0
10
24
4.34
3.24
3.5
2.4
86.71
89.09
%
—
10
24
11
29
3.97
3.24
3.3
2.4
7.48
7.93
kpa
0.42
11
29
9
20
4.67
3.15
1.0
1.0
—
—
u/ml
—
0
0
9
21
4.45
3.03
1.0
1.3
—
—
—
0
0
33
180
2.02
3.03
5.8
3.3
7.46
5.65
e9/l
0.19
23
150
10
26
4.01
3.03
2.7
2.2
58.40
57.71
%
—
10
26
5
5
10.23
2.99
2.2
3.4
23.80
25.40
%
—
5
5
29
152
2.08
2.96
3.0
2.0
0.00
0.00
estimate
—
6
37
8
17
4.87
2.95
1.9
1.0
281.00
265.09
mosm/kgh2o
—
8
11
7
13
5.55
2.89
6.0
1.4
-0.57
1.57
mmol/l
—
7
13
44
271
1.82
2.82
5.0
3.1
3.34
2.46
e6/l
0.22
29
124
74
529
1.67
2.80
9.6
3.5
7.41
7.39
ph
2.57
62
379
90
677
1.65
2.80
25.9
10.8
0.00
0.00
e9/l
0.30
74
552
88
663
1.63
2.69
6.2
3.9
6.28
6.28
ph
0.01
51
374
84
627
1.63
2.65
2.6
2.2
—
—
—
0
0
47
304
1.73
2.54
2.1
1.4
2.31
2.78
g/l
0.95
40
163
96
746
1.60
2.54
2.6
2.2
95.23
95.63
pmol/l
0.02
61
384
7
16
4.50
2.50
1.6
1.2
—
—
—
0
0
16
71
2.37
2.42
5.2
3.8
36.95
36.91
°c
0.33
16
71
6
12
5.13
2.42
3.5
1.0
86.47
91.03
%
—
6
12
6
12
5.13
2.42
1.0
1.2
4.80
4.63
u/l
—
6
12
6
12
5.13
2.42
1.7
1.2
—
—
—
0
0
17
78
2.30
2.39
3.5
2.1
0.00
0.00
estimate
—
6
32
9
31
3.00
2.10
3.9
2.1
113.78
129.14
g/l
—
9
22
6
15
4.10
2.05
2.8
1.3
3.53
3.06
u/ml
—
6
15
62
453
1.56
2.04
15.0
6.0
—
—
—
0
0
7
21
3.42
1.98
2.3
11.3
10.01
6.69
mmol/l
—
7
15
5
11
4.64
1.95
1.2
1.2
—
—
—
0
0
101
831
1.48
1.85
7.7
4.3
0.00
9.18
estimate
0.50
27
177
6
18
3.41
1.76
1.0
1.0
—
—
—
0
0
5
13
3.92
1.72
1.0
1.0
—
—
—
0
0
17
91
1.96
1.67
5.7
2.3
1.42
1.16
%
0.33
17
91
33
217
1.64
1.67
1.3
1.3
—
—
—
0
0
62
472
1.47
1.64
9.5
4.3
0.00
0.00
estimate
-0.00
25
154
5
14
3.64
1.62
2.2
3.1
—
—
—
0
0
54
401
1.49
1.61
1.3
1.3
—
—
—
0
0
70
550
1.44
1.56
4.9
3.9
16.52
6.86
mg/mmol
1.24
51
339
98
820
1.42
1.54
8.0
4.3
0.00
0.00
estimate
-0.00
26
169
5
15
3.40
1.53
1.4
1.1
—
—
—
0
0
5
16
3.18
1.44
5.2
4.1
864.80
795.13
mg
—
5
16
7
29
2.47
1.40
1.1
1.2
—
—
—
0
0
7
29
2.47
1.40
3.0
1.4
1532.71
360.73
mu/l
—
7
29
16
90
1.85
1.38
5.3
2.3
0.63
0.63
%
0.02
16
90
6
23
2.66
1.38
2.2
1.1
—
—
—
0
0
5
17
2.99
1.37
1.2
1.3
—
—
—
0
0
98
835
1.37
1.31
8.0
4.4
0.00
0.02
estimate
0.50
25
162
50
638
0.70
1.31
2.4
1.9
1.43
1.25
mmol/l
1.06
44
529
5
18
2.83
1.29
1.2
1.4
—
—
—
0
0
5
18
2.83
1.29
1.2
1.4
—
—
—
0
0
5
18
2.83
1.29
1.2
1.4
—
—
—
0
0
5
18
2.83
1.29
1.2
1.4
—
—
—
0
0
69
557
1.38
1.28
4.3
3.1
6.77
7.22
mmol/l
0.51
63
463
8
36
2.28
1.26
1.1
1.2
—
—
—
0
0
67
542
1.37
1.22
4.4
3.2
73.98
37.23
mg/l
1.16
52
347
6
26
2.35
1.19
1.8
1.0
14.97
11.00
u/l
—
6
21
31
223
1.47
1.08
1.2
1.3
—
—
—
0
0
12
67
1.85
1.07
3.4
2.5
—
—
—
0
0
13
75
1.79
1.06
2.5
1.8
—
—
—
0
0
132
1425
0.74
1.03
5.5
5.3
1.40
1.48
mmol/l
1.18
123
1296
51
405
1.36
1.03
6.0
2.8
348.98
350.32
umol/l
0.02
44
349
9
48
1.92
1.02
1.6
1.2
—
—
—
0
0
13
76
1.76
1.02
41.4
4.5
1.78
1.55
%
0.26
13
71
5
23
2.21
0.98
2.8
2.0
—
—
—
0
0
123
1113
1.32
0.97
4.9
4.3
15.06
14.95
pmol/l
0.15
116
991
134
1433
0.76
0.86
5.7
5.4
4.14
4.52
mmol/l
4.44
126
1314
5
24
2.11
0.75
2.8
2.0
104.60
106.38
mmol/l
—
5
24
5
24
2.11
0.75
2.8
2.0
1.15
1.21
mmol/l
—
5
24
5
24
2.11
0.75
2.8
2.0
3.96
4.04
mmol/l
—
5
24
12
76
1.62
0.73
1.7
1.3
—
—
—
0
0
7
39
1.83
0.73
14.6
1.8
60.33
57.89
%
—
7
39
11
69
1.63
0.70
48.9
4.7
0.97
0.89
%
0.31
11
63
5
27
1.87
0.69
13.2
2.7
19.60
17.37
u/ml
—
5
27
16
111
1.48
0.68
6.2
3.6
—
—
—
0
0
40
483
0.78
0.67
4.1
3.4
—
—
—
0
0
31
249
1.29
0.59
1.2
1.3
7.11
8.50
u/ml
—
9
91
139
1460
0.80
0.58
6.1
6.4
2.26
2.61
mmol/l
4.91
130
1333
6
36
1.69
0.57
82.8
6.3
3.00
1.19
mmol/l
—
6
31
9
62
1.47
0.54
1.0
1.7
—
—
—
0
0
25
306
0.79
0.47
2.9
3.5
0.72
0.82
ug/l
0.26
18
211
129
1353
0.84
0.45
5.2
4.5
1.33
1.25
mmol/l
0.73
121
1219
136
1420
0.84
0.44
5.7
5.7
6.25
6.04
mmol/l
0.77
126
1283
150
1443
1.22
0.43
59.1
14.8
27.94
23.43
mg/l
1.10
143
1179
14
105
1.36
0.42
1.1
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
2.4
—
—
—
0
0
5
34
1.48
0.40
6.0
2.2
15.58
7.52
pmol/l
—
5
34
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
0.17
—
0
11
5
36
1.40
0.38
8.4
1.6
62.60
58.53
%
—
5
36
33
283
1.20
0.38
1.2
1.3
95.14
30.81
iu/ml
—
7
94
48
536
0.86
0.36
5.5
6.1
2.38
3.05
ug/l
0.36
43
468
9
120
0.74
0.28
1.4
1.2
—
—
—
0
0
68
632
1.12
0.28
9.0
4.2
0.00
0.00
estimate
-0.00
23
141
5
72
0.69
0.26
1.8
1.4
—
—
—
0
0
120
1154
1.12
0.26
59.1
20.4
15.02
13.79
%
8.56
120
1143
5
39
1.29
0.23
1.2
1.1
—
—
—
0
0
7
95
0.73
0.23
1.7
1.2
—
—
—
0
0
5
41
1.23
0.22
1.0
1.3
—
—
—
0
0
41
375
1.12
0.22
8.8
4.8
1.02
1.02
kg/l
0.11
34
261
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
2.45
—
0
14
0
14
0.00
0.20
0.0
1.1
—
275.00
—
0
8
6
49
1.23
0.20
10.3
5.2
—
—
—
0
0
10
122
0.81
0.19
1.5
1.5
—
—
—
0
0
151
1539
0.89
0.19
79.6
24.7
37.27
39.93
%
8.73
151
1520
151
1539
0.89
0.19
78.5
24.5
122.12
134.13
g/l
13.02
151
1520
151
1539
0.89
0.19
77.7
24.2
30.42
30.33
pg
0.19
151
1520
151
1538
0.90
0.18
77.7
24.2
92.64
91.33
fl
1.91
151
1519
11
92
1.21
0.16
2.5
2.5
—
—
—
0
0
9
82
1.10
0.15
4.8
3.2
3.64
4.25
pmol/l
—
9
71
15
132
1.15
0.13
2.1
1.5
—
—
—
0
0
33
348
0.94
0.09
1.4
1.2
0.94
1.06
u/ml
—
10
90
137
1354
1.05
0.06
5.9
5.4
2.12
1.97
mu/l
0.61
128
1208
138
1393
0.96
0.05
8.2
7.1
40.62
39.71
mmol/mol
0.53
131
1285
46
447
1.04
0.04
7.3
3.5
0.00
0.00
estimate
-0.00
21
135
151
1522
0.95
0.04
65.2
21.4
107.37
79.41
umol/l
3.73
151
1502
147
1464
1.02
0.00
45.3
13.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
243.71
—
0
7
0
6
0.00
-0.00
0.0
7.8
—
0.74
—
0
6
0
6
0.00
-0.00
0.0
8.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
120.00
—
0
6
0
5
0.00
-0.00
0.0
9.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1.58
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
28.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.34
—
0
5
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
14.3
—
700.50
—
0
6

Mortality – FinRegistry

Association

Association between endpoint AB1_LISTERIOSIS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_LISTERIOSIS 4.859 [2.89, 8.17] < 0.001
Birth year 0.999 [0.99, 1.01] 0.824

During the follow-up period (1.1.1998 — 31.12.2019), 205 out of 348 females with AB1_LISTERIOSIS died.

Males

Parameter HR [95% CI] p-value
AB1_LISTERIOSIS 4.353 [2.43, 7.78] < 0.001
Birth year 0.985 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 223 out of 356 males with AB1_LISTERIOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_LISTERIOSIS.

N-year risk Females Males
1 0.565% 0.673%
5 3.177% 4.698%
10 7.736% 11.197%
15 14.768% 20.144%
20 25.68% 32.273%

Relationships between endpoints

Index endpoint: AB1_LISTERIOSIS – Listeriosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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