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Haemorrhagic and haematological disorders of fetus and newborn

P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P50-P61
  • Cause of death: ICD-10 P50-P61

2 out of 7 registries used, show all original rules.

749

4. Check minimum number of events

None

749

5. Include endpoints

749

6. Filter based on genotype QC (FinnGen only)

663

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Morbositates haemorrhagicae et haematologicae fetus et neonati

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 663 354 309
Unadjusted period prevalence (%) 0.13 0.13 0.14
Median age at first event (years) 0.01 0.01 0.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
703
Matched controls
6711
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
2789.2
307.7
320
*
P07.3
ICD-10 Finland
Other preterm infants
18.8
256.2
240
180
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
222.9
205
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
9.1
118.5
171
230
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
13.5
44.8
44
33
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
6.1
37.0
69
118
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
10.0
32.0
38
38
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
22.6
22
*
WX722
NOMESCO Finland
PEEP
4.6
22.1
55
121
P55.1
ICD-10 Finland
ABO isoimmunization of fetus and newborn
+∞
21.6
21
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.5
21.2
80
239
602
Kela drug reimbursment
Children's severe malnutrition
3.5
19.6
71
206
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
5.7
18.7
36
63
P52.0
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn
+∞
18.5
18
*
P07.2
ICD-10 Finland
Extreme immaturity
16.9
18.3
29
17
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
15.4
15
*
P61.0
ICD-10 Finland
Transient neonatal thrombocytopenia
+∞
15.4
15
*
P61.1
ICD-10 Finland
Polycythaemia neonatorum
+∞
15.4
15
*
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.5
14.9
25
38
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
3.7
13.9
45
121
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.6
13.2
32
69
P55.0
ICD-10 Finland
Rh isoimmunization of fetus and newborn
+∞
12.3
12
*
P61.4
ICD-10 Finland
Other congenital anaemias, not elsewhere classified
+∞
12.3
12
*
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
12.3
12
*
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
9.8
12.2
24
24
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
11.5
11.0
20
17
WX882
NOMESCO Finland
High dependency care
2.1
10.8
107
518
Z2446
NOMESCO Finland
Social worker
1.9
10.4
156
875
P22.8
ICD-10 Finland
Other respiratory distress of newborn
8.9
10.2
21
23
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
4.8
9.7
22
45
P05.0
ICD-10 Finland
Light for gestational age
8.2
9.3
20
24
P61.2
ICD-10 Finland
Anaemia of prematurity
+∞
9.2
9
*
P57.9
ICD-10 Finland
Kernicterus, unspecified
+∞
9.2
9
*
WX730
NOMESCO Finland
Conventional respirator
4.6
9.2
22
47
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
8.9
162
963
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.8
221
1435
P05.1
ICD-10 Finland
Small for gestational age
4.1
8.8
24
57
R4110
NOMESCO Finland
Physiotherapy
1.7
8.6
198
1255
A03FA02
ATC
cisapride; oral, rectal
3.3
8.5
33
100
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
4.1
8.1
22
52
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.1
195
1248
H35.1
ICD-10 Finland
Retinopathy of prematurity
10.4
8.1
15
14
Z3226
NOMESCO Finland
Physiotherapist
1.7
8.0
183
1156
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.2
7.9
66
298
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
3.8
7.9
24
62
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
10.5
7.6
14
13
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
8.2
7.6
16
19
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
7.5
159
981
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.0
7.5
21
51
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
12.9
7.2
12
9
P07.1
ICD-10 Finland
Other low birth weight
12.9
7.2
12
9
P61.3
ICD-10 Finland
Congenital anaemia from fetal blood loss
+∞
7.2
7
*
P52.4
ICD-10 Finland
Intracerebral (nontraumatic) haemorrhage of fetus and newborn
+∞
7.2
7
*
Z3231
NOMESCO Finland
Registered nurse
1.6
7.1
273
1946
Z31.5
ICD-10 Finland
Genetic counselling
2.0
7.1
78
392
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
7.1
165
1044
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
3.6
7.0
23
63
NF1DA
NOMESCO Finland
X-ray of hips
4.5
6.9
17
37
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
4.2
6.8
18
42
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.7
77
393
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.1
6.6
28
90
F83
ICD-10 Finland
Mixed specific developmental disorders
2.1
6.6
60
280
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
9.0
6.6
13
14
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.4
6.5
45
187
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
6.3
108
625
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.3
87
472
ZXD20
NOMESCO Finland
Day surgery
2.0
6.3
68
340
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
6.2
40
161
P52.1
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 2, of fetus and newborn
+∞
6.1
6
*
JKD50
NOMESCO Finland
Hepatoportoenterostomy
8.9
6.1
12
13
Q44.29
ICD-10 Finland
Atresia of bile ducts
8.9
6.1
12
13
A11JC
ATC
Vitamins, other combinations
5.3
6.1
17
31
Z2221
NOMESCO Finland
Medical doctor
1.6
6.1
172
1138
J45.8
ICD-10 Finland
Mixed asthma
2.9
6.0
27
90

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
123
699
1.82
7.73
16.0
7.9
17.08
6.00
umol/l
1.56
112
581
259
1849
1.53
6.59
19.0
9.0
41.61
21.79
umol/l
4.32
245
1708
20
64
3.04
4.81
2.5
2.2
—
—
—
0
0
405
3367
1.35
3.69
15.4
12.8
0.00
0.01
e9/l
0.75
312
2551
127
875
1.47
3.58
7.0
5.6
1.23
1.82
mg/l
1.14
86
633
124
873
1.43
3.12
18.0
15.1
0.82
0.81
mmol/l
0.33
124
847
335
2756
1.31
3.06
13.9
11.4
—
—
—
0
0
224
1745
1.33
3.02
12.2
10.2
38.00
38.27
g/l
0.29
218
1670
112
786
1.43
2.86
3.9
3.7
21.01
21.39
%
0.10
107
768
175
1336
1.33
2.67
3.8
3.1
2.40
2.41
mmol/l
0.18
165
1249
59
368
1.58
2.66
1.6
1.3
—
—
—
0
0
61
385
1.56
2.62
4.3
9.6
258.20
414.47
mg/l
0.63
45
319
407
3480
1.28
2.58
13.6
10.4
47.73
48.91
%
1.04
394
3388
13
48
2.62
2.49
4.4
3.2
—
—
—
0
0
54
336
1.58
2.47
2.9
2.5
104.20
94.65
au/ml
0.21
20
144
5
7
6.86
2.47
1.0
1.0
—
—
—
0
0
5
7
6.86
2.47
1.0
1.0
—
—
—
0
0
5
7
6.86
2.47
1.0
1.0
—
—
—
0
0
5
7
6.86
2.47
1.0
1.0
—
—
—
0
0
5
7
6.86
2.47
1.0
1.0
—
—
—
0
0
413
3549
1.27
2.46
13.8
10.5
36.79
35.59
%
1.25
398
3442
37
209
1.73
2.45
8.7
6.4
1.24
1.24
mmol/l
0.10
31
188
11
37
2.87
2.35
1.7
2.5
—
—
—
0
0
601
5440
1.38
2.33
25.5
17.8
13.29
13.09
%
3.20
590
5364
9
27
3.21
2.27
1.9
3.3
54.44
35.33
u/l
—
9
27
400
3443
1.25
2.27
14.0
10.7
8.38
8.44
%
0.19
379
3306
424
3674
1.26
2.27
13.7
11.5
0.22
0.22
e9/l
0.06
363
3086
28
149
1.83
2.27
2.0
1.4
315.59
375.56
ug/g
0.78
19
80
132
994
1.33
2.20
6.0
4.4
—
—
—
0
0
420
3643
1.25
2.20
13.2
10.5
2.46
2.35
e9/l
0.94
359
3093
8
23
3.35
2.16
1.8
2.0
5.87
4.70
mmol/24h
—
8
23
413
3580
1.25
2.15
13.1
10.6
0.60
0.56
e9/l
1.80
341
2949
120
894
1.34
2.15
2.0
1.8
—
—
—
0
0
27
145
1.81
2.14
2.8
2.0
—
—
—
0
0
28
153
1.78
2.10
2.4
2.0
—
—
—
0
0
412
3579
1.24
2.07
13.1
10.6
0.04
0.04
e9/l
1.86
340
2953
58
383
1.49
2.07
11.9
5.8
0.09
0.09
%
0.01
22
118
106
780
1.35
2.06
2.0
1.9
—
—
—
0
0
173
1364
1.28
2.05
16.0
13.0
1.36
1.35
mmol/l
0.27
168
1304
355
3039
1.23
2.03
10.4
6.3
142.39
126.05
u/l
2.17
339
2881
396
3430
1.23
2.02
14.1
10.7
3.07
3.26
%
0.81
380
3299
56
370
1.48
2.00
10.7
5.2
0.26
0.36
%
0.38
21
134
69
475
1.43
2.00
2.3
2.1
163.04
164.38
u/ml
0.01
38
214
183
1461
1.26
1.95
3.5
5.4
8.05
9.02
mmol/l
1.46
176
1390
52
340
1.50
1.95
3.0
2.5
—
—
—
0
0
429
3758
1.23
1.93
16.4
12.2
3.40
3.42
e9/l
0.05
353
3080
37
225
1.60
1.91
2.8
2.2
—
—
—
0
0
37
225
1.60
1.91
2.8
2.2
—
—
—
0
0
37
225
1.60
1.91
2.8
2.2
—
—
—
0
0
37
225
1.60
1.91
2.8
2.2
—
—
—
0
0
394
3425
1.22
1.89
14.3
10.7
0.65
0.63
%
0.42
379
3305
176
1407
1.26
1.85
6.5
4.0
—
—
—
0
0
163
1293
1.26
1.83
17.0
10.0
—
—
—
0
0
201
1635
1.24
1.82
3.9
3.7
2.73
2.52
mg/l
0.39
182
1477
597
5444
1.31
1.81
11.8
8.6
—
—
—
0
0
565
5119
1.27
1.78
14.6
10.2
26.92
24.74
u/l
1.45
552
4974
342
2957
1.20
1.66
13.9
9.6
5.97
5.98
mmol/l
0.03
326
2816
17
86
1.91
1.65
2.1
1.7
—
—
—
0
0
152
1212
1.25
1.63
6.0
3.9
—
—
—
0
0
8
30
2.56
1.63
1.4
1.7
1636.63
2031.40
ml
—
8
30
15
73
1.98
1.62
2.1
2.5
—
—
—
0
0
64
454
1.38
1.60
2.4
1.8
2.43
2.41
mmol/l
0.39
52
385
10
41
2.35
1.59
4.8
1.9
33.10
31.66
pg
—
10
41
56
389
1.41
1.58
12.2
5.8
0.29
0.50
%
0.65
21
136
149
1190
1.25
1.58
4.2
3.7
578.77
598.54
mosm/kgh2o
0.42
132
1053
62
439
1.38
1.57
1.6
1.4
605.02
17048803.34
pmol/l
0.50
56
393
181
1478
1.23
1.56
18.1
10.2
7.40
7.41
ph
0.93
151
1182
26
153
1.65
1.56
3.1
2.7
—
—
—
0
0
43
285
1.47
1.55
1.5
1.7
—
—
—
0
0
54
374
1.41
1.55
12.4
5.8
0.00
0.04
%
0.64
18
121
152
1219
1.24
1.55
5.5
6.5
1.11
1.16
inr
0.55
127
1009
181
1480
1.23
1.54
18.2
10.2
5.10
5.00
kpa
1.14
173
1440
22
124
1.72
1.54
7.5
7.1
7.39
7.40
ph
0.10
22
124
89
670
1.31
1.51
8.7
5.4
76.46
62.04
e9/l
1.20
57
390
309
2671
1.19
1.44
23.7
16.2
1.23
1.23
mmol/l
0.16
297
2574
261
2223
1.19
1.44
9.7
8.7
—
—
—
0
0
7
27
2.49
1.43
1.6
1.2
—
—
—
0
0
18
98
1.77
1.42
4.4
4.0
1.54
4.37
%
—
8
40
14
70
1.93
1.42
1.0
1.1
—
—
—
0
0
10
44
2.19
1.39
1.4
1.3
—
—
—
0
0
18
99
1.76
1.38
8.1
7.4
10.06
9.17
kpa
1.09
18
99
18
99
1.76
1.38
8.1
7.8
1.76
1.59
mmol/l
—
9
49
18
99
1.76
1.38
8.1
7.8
5.01
4.86
kpa
0.28
18
99
23
136
1.64
1.37
5.8
4.4
—
—
—
0
0
11
51
2.08
1.35
1.0
1.1
—
—
—
0
0
164
1345
1.21
1.35
15.9
9.8
23.94
24.04
mmol/l
0.23
159
1340
65
481
1.32
1.27
2.8
2.6
34.06
28.58
u/l
0.28
54
385
9
42
2.06
1.27
1.0
1.1
—
—
—
0
0
19
110
1.67
1.24
1.3
1.4
—
—
—
0
0
249
2137
1.17
1.23
3.6
3.6
6.35
6.37
ph
0.10
107
954
14
74
1.82
1.23
1.9
1.3
—
—
—
0
0
153
1261
1.20
1.20
3.2
2.6
—
—
—
0
0
18
104
1.67
1.19
1.1
1.3
11.36
3.24
u/ml
0.97
11
63
78
598
1.28
1.19
18.8
17.4
106.94
105.79
mmol/l
1.99
78
598
130
1056
1.21
1.18
2.3
1.8
—
—
—
0
0
149
1227
1.20
1.18
4.5
4.4
3.20
2.73
e6/l
0.24
80
651
53
386
1.34
1.17
1.8
1.5
—
—
—
0
0
150
1243
1.19
1.11
5.2
3.9
6.90
6.88
e6/l
0.01
135
1115
145
1198
1.20
1.11
1.3
1.3
—
—
—
0
0
7
30
2.24
1.09
1.1
1.2
—
—
—
0
0
320
2820
1.15
1.09
20.9
14.2
1.23
1.23
mmol/l
0.21
298
2646
16
92
1.68
1.09
1.6
1.5
—
—
—
0
0
41
291
1.37
1.08
1.9
1.9
—
—
—
0
0
228
1962
1.16
1.07
6.2
5.1
19.32
26.81
e6/l
0.48
169
1453
48
351
1.33
1.05
1.0
1.0
8.94
8.83
mu/l
0.04
41
304
351
3121
1.15
1.04
5.2
4.1
548.50
204.77
e6/l
0.28
12
31
12
64
1.80
1.04
1.0
1.0
—
—
—
0
0
15
86
1.68
1.03
13.5
9.5
5.63
5.20
pmol/l
0.22
15
86
15
86
1.68
1.03
1.7
1.4
1.26
1.27
mm
—
8
66
17
101
1.62
1.03
1.1
1.1
—
—
—
0
0
39
277
1.36
1.03
4.7
3.8
0.54
0.21
e6/l
0.55
39
265
22
140
1.52
1.02
7.8
5.9
—
—
—
0
0
14
80
1.68
0.98
7.4
2.4
—
—
—
0
0
203
1744
1.16
0.97
1.7
1.6
—
—
—
0
0
46
339
1.32
0.97
5.5
3.8
—
—
—
0
0
262
2296
1.14
0.94
7.4
6.2
68.19
55.52
e6/l
0.16
173
1507
99
803
1.21
0.94
1.5
1.5
215.20
438.76
u/ml
1.05
88
759
108
884
1.20
0.93
1.3
1.3
—
52.50
—
0
7
32
225
1.37
0.91
5.6
4.4
—
—
—
0
0
161
1366
1.16
0.91
17.2
13.7
—
—
—
0
0
146
1233
1.16
0.88
4.6
4.2
0.74
0.86
e6/l
0.27
75
652
23
154
1.44
0.86
4.9
3.9
—
—
—
0
0
123
1028
1.17
0.84
4.9
3.2
57.47
57.23
u/l
0.01
116
964
37
271
1.32
0.83
32.6
25.4
0.72
0.69
%
0.19
37
271
14
85
1.58
0.81
1.1
1.4
—
—
—
0
0
6
31
1.85
0.80
5.7
2.7
3.82
3.82
mmol/l
—
6
31
15
93
1.55
0.80
1.7
1.4
—
—
—
0
0
210
1833
1.13
0.79
5.9
3.9
—
—
estimate
—
0
0
281
2497
1.12
0.79
4.4
3.9
0.00
0.00
estimate
-0.00
55
427
0
24
0.00
0.79
0.0
2.8
—
1.22
—
0
24
136
1154
1.16
0.77
4.5
3.8
0.00
0.00
estimate
-0.00
54
401
597
5559
1.17
0.75
19.0
12.6
23.73
24.13
mg/l
0.10
427
3938
70
564
1.21
0.74
1.7
1.9
—
—
—
0
0
282
2518
1.12
0.72
4.5
3.9
0.00
2.96
estimate
0.50
55
415
9
54
1.60
0.72
1.0
1.1
301.89
278.15
mg/l
—
9
54
67
540
1.20
0.71
2.6
2.4
5.72
7.79
iu/l
0.86
42
335
47
365
1.25
0.70
27.3
19.6
15.72
15.76
kpa
0.02
47
355
47
365
1.25
0.70
27.4
19.6
5.18
5.30
kpa
0.46
47
355
5
25
1.92
0.70
1.0
1.2
—
—
—
0
0
21
145
1.39
0.69
2.5
2.3
0.00
0.00
estimate
—
10
68
208
1829
1.12
0.69
5.9
4.9
0.67
0.19
e6/l
0.68
146
1320
47
366
1.24
0.69
27.4
19.6
7.42
7.38
ph
2.30
17
111
14
89
1.51
0.69
1.1
1.4
—
—
—
0
0
71
578
1.19
0.68
2.7
1.9
—
—
—
0
0
22
281
0.74
0.67
1.0
1.1
—
—
—
0
0
5
91
0.52
0.67
4.6
2.5
—
—
—
0
0
327
3290
0.90
0.66
3.0
2.5
5.31
5.30
mmol/l
0.05
299
3030
15
98
1.47
0.66
1.1
1.1
—
—
—
0
0
102
859
1.16
0.66
1.5
1.5
21.51
18.25
nmol/l
1.49
86
777
59
474
1.21
0.65
2.7
2.3
8.92
8.73
nmol/l
0.05
54
426
5
27
1.77
0.65
13.4
3.4
10.60
11.48
mmol/l
—
5
21
5
27
1.77
0.65
13.4
3.4
108.00
105.81
mmol/l
—
5
21
663
6242
1.25
0.65
27.1
18.8
273.51
272.26
e9/l
0.17
641
5937
7
42
1.60
0.65
1.0
1.2
210.00
259.30
iu/ml
—
7
42
663
6243
1.24
0.64
26.9
18.7
86.14
85.98
fl
0.35
658
6163
664
6254
1.24
0.63
27.0
18.7
6.88
6.90
e9/l
0.05
641
5931
8
47
1.63
0.62
8.8
7.4
—
—
—
0
0
18
124
1.40
0.61
3.4
3.7
3.49
3.28
e9/l
0.21
18
124
137
1184
1.13
0.61
4.4
2.9
0.00
0.00
estimate
-0.00
45
337
663
6246
1.23
0.61
27.0
18.7
4.62
4.63
e12/l
0.21
639
5923
663
6246
1.23
0.61
26.9
18.7
29.00
28.91
pg
0.51
658
6167
12
76
1.52
0.61
2.3
1.8
18.14
22.30
mg/l
—
7
40
15
100
1.44
0.60
9.5
3.2
24.77
22.91
mmol/l
0.78
15
95
280
2519
1.10
0.60
4.5
3.9
0.00
0.00
estimate
-0.00
53
414
663
6247
1.23
0.60
29.7
20.4
39.66
40.18
%
0.44
657
6167
53
597
0.84
0.59
1.2
1.2
11.03
17.38
iu/ml
1.30
12
99
27
201
1.29
0.58
5.3
9.8
25.07
23.97
mmol/l
1.03
27
189
663
6249
1.23
0.58
27.8
19.1
133.40
133.14
g/l
0.17
658
6171
151
1318
1.12
0.58
3.5
3.7
66.99
96.31
ug/g
1.57
124
1054
272
2451
1.10
0.56
5.0
4.1
69.13
67.36
nmol/l
0.52
250
2346
40
315
1.23
0.56
2.0
2.1
0.00
0.00
estimate
-0.00
16
86
19
135
1.35
0.55
1.6
1.5
—
—
—
0
0
9
57
1.51
0.54
19.1
8.3
1.27
1.22
mmol/l
—
9
52
287
2597
1.09
0.54
9.9
5.0
43.41
26.11
u/l
2.14
271
2497
31
238
1.25
0.54
5.7
4.3
38.48
6.75
e6/l
0.41
23
159
31
239
1.25
0.52
5.8
4.3
390.57
902.78
e6/l
0.43
23
168
9
60
1.44
0.52
8.7
2.8
1.07
1.23
mmol/l
—
9
51
6
38
1.51
0.52
1.0
1.1
—
—
—
0
0
308
2801
1.09
0.51
3.7
2.9
1.06
1.07
mmol/l
0.06
295
2660
136
1190
1.11
0.51
8.6
5.5
—
—
—
0
0
6
39
1.47
0.50
1.5
1.3
—
—
—
0
0
6
39
1.47
0.50
7.2
1.1
48.50
22.90
u/l
—
6
34
33
259
1.23
0.49
1.6
1.5
1.44
2.97
u/ml
0.97
21
189
69
580
1.15
0.48
2.7
2.4
4.56
5.73
u/l
0.82
41
335
34
270
1.21
0.46
1.0
1.0
2.98
3.24
kpa
0.58
28
224
7
47
1.43
0.46
1.4
1.5
—
—
—
0
0
7
47
1.43
0.46
1.4
1.5
—
—
—
0
0
7
47
1.43
0.46
1.4
1.5
—
—
—
0
0
7
47
1.43
0.46
1.1
1.1
—
87.56
—
0
9
24
183
1.26
0.45
1.4
1.4
—
—
—
0
0
59
494
1.15
0.44
3.7
4.5
50.20
109.56
mg/l
0.92
51
416
62
669
0.87
0.44
4.1
3.9
487.09
1367.08
ng/l
1.91
33
372
28
219
1.23
0.43
5.8
3.8
1826.86
1444.17
e6/l
0.59
21
148
24
280
0.81
0.41
1.2
1.2
—
—
—
0
0
130
1149
1.10
0.41
6.9
4.3
7.38
7.38
ph
0.01
78
777
0
15
0.00
0.41
0.0
2.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
22.02
—
0
11
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
18
217
0.79
0.41
1.7
4.2
—
—
—
0
0
34
274
1.19
0.41
1.0
1.0
—
—
—
0
0
34
274
1.19
0.41
1.0
1.0
-1.88
-2.39
mmol/l
—
8
69
34
274
1.19
0.41
1.0
1.0
7.54
7.34
kpa
0.27
28
227
78
671
1.12
0.40
2.6
2.6
—
—
—
0
0
35
283
1.19
0.40
26.7
18.8
112.17
121.63
g/l
2.06
35
278
167
1495
1.09
0.40
13.9
11.7
0.95
1.03
mmol/l
0.12
150
1220
16
118
1.30
0.39
1.2
1.1
—
—
—
0
0
0
18
0.00
0.39
0.0
2.0
—
—
—
0
0
0
18
0.00
0.39
0.0
2.0
—
—
—
0
0
25
197
1.22
0.37
5.8
5.0
—
—
—
0
0
51
550
0.88
0.37
1.2
1.2
1.86
7.95
u/ml
1.28
14
150
167
1501
1.08
0.37
14.8
11.7
7.38
7.37
ph
1.96
124
1033
11
77
1.37
0.37
1.9
3.2
497.55
111.00
u/ml
0.35
11
64
6
40
1.44
0.35
2.7
6.5
222.00
226.68
ug/l
—
6
40
167
1504
1.08
0.35
14.2
11.6
5.79
5.82
kpa
0.19
167
1470
27
217
1.20
0.34
5.5
3.7
229.42
189.88
e6/l
0.40
19
144
30
244
1.18
0.34
1.6
1.6
14.31
15.04
u/ml
0.02
20
170
16
121
1.27
0.34
1.1
1.2
—
—
—
0
0
118
1050
1.09
0.33
1.7
1.7
—
—
—
0
0
161
1452
1.08
0.33
14.3
11.4
4.98
5.11
kpa
0.49
161
1422
6
82
0.70
0.33
1.0
1.1
—
—
—
0
0
297
2934
0.94
0.32
4.6
3.4
34.87
35.42
mmol/mol
0.44
277
2787
31
342
0.86
0.32
1.2
1.4
—
—
—
0
0
86
886
0.92
0.30
1.6
1.9
—
—
—
0
0
27
221
1.17
0.29
5.6
3.8
0.47
0.37
e9/l
0.29
18
133
31
257
1.16
0.29
3.9
7.3
160.69
229.03
ng/l
0.44
26
237
26
213
1.17
0.28
5.4
3.7
757.39
526.96
e6/l
0.88
18
141
86
882
0.92
0.27
1.5
1.9
—
—
—
0
0
530
4982
1.06
0.27
23.6
15.2
3.95
3.93
mmol/l
0.76
514
4838
9
115
0.74
0.27
1.3
1.4
13.19
14.51
u/ml
—
9
106
10
73
1.31
0.27
1.1
1.1
156.60
186.08
mg/l
—
10
68
41
436
0.89
0.26
1.8
1.4
—
—
—
0
0
86
880
0.92
0.26
1.5
1.9
—
—
—
0
0
45
388
1.11
0.25
1.1
1.1
1.07
0.81
u/ml
0.10
27
199
18
144
1.20
0.25
2.4
1.8
2.98
3.35
iu/l
—
6
58
10
121
0.79
0.25
1.5
1.6
—
—
—
0
0
10
74
1.29
0.25
1.1
1.0
—
—
—
0
0
10
74
1.29
0.25
1.5
1.1
—
—
—
0
0
86
877
0.93
0.24
1.5
1.9
—
—
—
0
0
17
192
0.84
0.24
1.2
1.1
5.92
18.18
u/ml
—
6
29
278
2577
1.05
0.24
1.9
1.8
1.50
1.49
g/l
0.01
142
1371
12
92
1.25
0.24
2.2
2.4
—
—
—
0
0
72
639
1.08
0.23
1.2
1.2
0.99
1.30
u/ml
0.27
49
450
10
75
1.28
0.23
4.2
3.2
—
—
—
0
0
5
37
1.29
0.23
1.0
1.1
—
—
—
0
0
5
38
1.26
0.22
1.4
1.2
—
—
—
0
0
18
146
1.18
0.22
2.2
1.6
—
—
—
0
0
242
2239
1.05
0.22
2.6
2.2
—
—
—
0
0
35
300
1.12
0.22
1.3
1.3
2.87
2.95
mmol/l
0.17
18
173
46
401
1.10
0.22
6.8
4.9
22.82
24.95
nmol/l
0.40
46
396
181
1664
1.05
0.21
3.4
3.2
—
0.20
—
0
5
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
14.0
—
—
—
0
0
8
98
0.78
0.21
1.0
1.3
—
—
—
0
0
177
1629
1.05
0.20
3.9
3.2
0.00
0.00
estimate
0.50
43
335
55
487
1.08
0.20
4.3
4.9
5.54
32.86
mg/mmol
0.50
47
407
16
178
0.85
0.20
42.7
24.6
9.77
11.48
%
1.17
16
178
331
3094
1.04
0.19
3.7
3.1
2.52
2.55
mmol/l
0.32
314
2934
39
406
0.91
0.19
1.8
2.4
—
—
—
0
0
29
249
1.12
0.18
1.3
1.1
5.37
14.46
eliau/ml
—
6
31
28
240
1.12
0.18
1.2
1.2
—
—
—
0
0
329
3077
1.04
0.18
3.6
3.1
1.36
1.39
mmol/l
1.19
312
2916
336
3144
1.04
0.18
5.1
3.8
57.02
49.47
ug/l
0.58
320
3017
12
136
0.84
0.18
1.0
1.0
1.45
1.47
g/l
0.11
12
136
29
250
1.11
0.17
1.4
1.6
1468.10
1108.47
nmol/l
1.05
21
189
167
1648
0.96
0.17
2.2
2.3
—
—
—
0
0
28
241
1.11
0.17
1.2
1.1
8.62
5.15
iu/ml
—
5
37
28
241
1.11
0.17
40.0
23.7
14.70
15.73
%
1.79
28
236
42
370
1.09
0.17
21.4
16.8
123.43
126.58
g/l
0.38
42
361
83
834
0.94
0.17
1.6
1.9
—
—
—
0
0
27
285
0.90
0.17
1.1
1.3
210.63
197.48
miu/ml
0.10
13
124
19
205
0.88
0.16
1.0
1.4
—
—
—
0
0
45
461
0.93
0.16
1.6
1.7
305.50
369.43
mu/l
1.25
40
435
17
142
1.15
0.16
6.0
5.1
438.35
445.76
umol/l
0.07
17
135
23
197
1.12
0.15
1.3
1.3
0.68
2.27
u/ml
0.78
18
140
83
755
1.06
0.15
2.0
1.7
380.00
517.57
titre
—
8
115
9
76
1.13
0.15
3.2
4.9
26.91
25.42
ug/l
—
9
76
80
728
1.06
0.15
2.5
2.5
11.96
44.73
ng/l
1.83
36
268
335
3144
1.03
0.15
3.8
3.2
4.15
4.24
mmol/l
1.27
317
3007
528
4993
1.04
0.14
23.6
15.2
139.44
139.47
mmol/l
0.10
512
4873
106
1051
0.96
0.14
1.7
2.0
—
—
—
0
0
36
370
0.92
0.14
1.4
1.1
—
—
—
0
0
20
171
1.12
0.14
1.6
1.3
—
—
—
0
0
142
1317
1.04
0.12
2.1
2.0
1.17
1.19
mmol/l
0.16
134
1230
13
141
0.88
0.12
1.6
1.4
—
—
—
0
0
71
649
1.05
0.12
1.2
1.2
5.39
6.45
u/ml
0.31
50
487
46
415
1.06
0.11
1.2
1.2
5.72
11.12
u/ml
1.12
30
270
557
5282
1.03
0.11
16.0
11.7
55.99
58.37
umol/l
1.93
548
5186
138
1284
1.03
0.10
2.9
3.0
1.02
1.02
kg/l
0.50
77
776
20
208
0.92
0.10
1.5
1.2
—
—
—
0
0
57
568
0.95
0.10
1.5
1.3
145.30
167.60
u/ml
0.17
21
151
116
1137
0.97
0.09
1.9
1.7
—
—
—
0
0
94
871
1.03
0.09
1.5
1.4
97.86
231.06
titre
—
7
34
75
692
1.04
0.09
1.3
1.3
2.76
2.99
u/ml
0.07
55
494
6
53
1.08
0.08
1.2
1.2
—
—
—
0
0
16
139
1.10
0.08
2.2
2.6
1.25
2.09
mmol/l
0.87
11
112
280
2707
0.98
0.08
2.0
2.0
2.84
3.47
u/ml
0.30
51
491
7
62
1.08
0.08
1.1
1.1
—
—
—
0
0
73
719
0.97
0.08
1.6
2.0
—
—
—
0
0
68
628
1.04
0.08
2.9
2.4
5606.08
8716.78
u/l
0.22
13
155
26
233
1.07
0.08
27.8
20.4
66.26
70.14
%
0.42
26
233
6
67
0.85
0.07
3.2
7.6
—
—
—
0
0
6
69
0.83
0.07
1.3
1.1
—
—
—
0
0
6
70
0.82
0.07
1.0
1.6
11.30
8.91
umol/l
—
6
70
31
312
0.95
0.07
1.6
1.9
6.17
6.36
ph
0.57
23
195
29
292
0.95
0.07
3.7
2.5
51.52
53.47
%
0.35
29
292
17
150
1.08
0.07
6.0
5.7
3.75
2.02
ug/l
1.49
17
150
29
263
1.05
0.06
1.5
1.3
—
—
—
0
0
9
100
0.86
0.06
1.0
1.0
—
—
—
0
0
21
188
1.07
0.06
5.5
5.7
7.38
7.32
ph
1.70
13
148
52
480
1.04
0.06
1.8
1.5
—
—
—
0
0
64
628
0.97
0.06
1.4
2.4
—
—
—
0
0
29
264
1.05
0.05
1.4
1.3
—
—
—
0
0
36
330
1.04
0.05
20.5
16.5
0.55
0.61
%
0.67
36
330
21
190
1.06
0.04
1.4
1.1
25.45
6.03
eliau/ml
—
6
50
14
125
1.07
0.03
1.6
1.2
—
0.20
—
0
6
29
287
0.96
0.03
1.9
1.6
0.36
0.16
mg/l
—
10
117
449
4270
1.01
0.03
4.4
3.7
14.34
14.45
pmol/l
0.45
406
3827
137
1294
1.01
0.03
1.9
1.6
90.46
97.22
pmol/l
1.11
71
683
494
4701
1.01
0.03
4.8
4.2
2.10
2.02
mu/l
0.80
463
4471
52
507
0.98
0.03
2.4
2.1
—
—
—
0
0
19
174
1.04
0.02
2.1
1.7
0.28
0.22
nmol/l
0.25
14
134
91
860
1.01
0.01
1.7
1.7
—
—
—
0
0
18
165
1.04
0.01
1.1
1.1
—
—
—
0
0
47
441
1.02
0.01
1.2
1.2
6.08
7.01
u/ml
0.11
31
296
31
303
0.98
0.01
1.1
1.1
—
—
—
0
0
10
90
1.06
0.00
1.2
1.1
35.55
30.17
iu/ml
—
10
90
22
205
1.03
0.00
3.6
3.9
3.73
8.27
index
1.26
11
130
25
234
1.02
0.00
1.1
1.1
—
—
—
0
0
12
113
1.01
0.00
1.1
1.5
—
215.00
—
0
8
66
630
1.00
0.00
1.2
1.2
7.63
3.26
u/ml
1.02
48
460
14
138
0.97
0.00
1.1
1.1
0.85
0.81
g/l
0.26
14
138
15
148
0.97
0.00
2.7
2.0
124.11
134.12
ng/l
0.29
15
140
33
312
1.01
0.00
1.5
1.6
830.69
1005.93
mu/l
0.72
27
294
29
275
1.01
0.00
1.3
1.2
—
—
—
0
0
10
100
0.95
0.00
4.5
4.9
1.00
0.64
index
—
10
100
0
5
0.00
0.00
0.0
1.0
—
76.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
0.10
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
6.92
—
0
5
5
53
0.90
0.00
6.8
2.8
1002.80
1134.21
u/ml
—
5
53
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
9
91
0.94
-0.00
8.1
2.2
25.83
23.87
mg/l
—
9
55
5
49
0.97
-0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1492.67
—
0
6
6
61
0.94
-0.00
1.2
1.3
113.67
119.79
pmol/l
—
6
61
8
81
0.94
-0.00
4.5
2.3
2.28
1.56
ug/l
—
8
74
6
58
0.99
-0.00
1.3
1.2
—
—
—
0
0
6
63
0.91
-0.00
22.0
3.7
4.57
4.98
kpa
—
6
63
5
50
0.95
-0.00
1.2
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
92.83
—
0
6
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
201.56
—
0
9
5
47
1.02
-0.00
4.4
2.5
31.56
17.63
umol/l
—
5
47
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
87
0.99
-0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
955.13
—
0
8
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO – Haemorrhagic and haematological disorders of fetus and newborn

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).