Disorders related to short gestation and low birth weight, not elsewhere classified

P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P07
  • Cause of death: ICD-10 P07

2 out of 7 registries used, show all original rules.

891

4. Check minimum number of events

None

891

5. Include endpoints

None

891

6. Filter based on genotype QC (FinnGen only)

776

Control definitions (FinnGen only)

Control exclude
P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[5-8]
Name in latin
Perturbationes ad gestationem brevem et pondus partuale leve pertinentes non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 51969 23864 28104
Only index persons 27383 12581 14802
Unadjusted period prevalence (%)
Whole population 0.74 0.68 0.79
Only index persons 0.52 0.46 0.57
Median age at first event (years)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 776 446 330
Unadjusted period prevalence (%) 0.16 0.16 0.15
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
832
Matched controls
8061
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P07.3
ICD-10 Finland
Other preterm infants
+∞
307.7
674
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
156.4
307.7
178
14
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
39.6
307.7
351
146
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
+∞
166.7
156
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
439.3
119.5
118
*
602
Kela drug reimbursment
Children's severe malnutrition
9.5
107.8
141
169
P05.1
ICD-10 Finland
Small for gestational age
+∞
97.8
93
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
+∞
97.8
93
*
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
197.6
88.1
91
5
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
10.4
81.8
97
101
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
25.1
79.6
58
24
WX722
NOMESCO Finland
PEEP
10.7
77.1
89
89
P07.1
ICD-10 Finland
Other low birth weight
+∞
73.2
70
*
P07.2
ICD-10 Finland
Extreme immaturity
+∞
73.2
70
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
6.3
64.6
120
210
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
634.9
61.9
61
*
P05.0
ICD-10 Finland
Light for gestational age
+∞
56.3
54
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
+∞
49.9
48
*
P70.1
ICD-10 Finland
Syndrome of infant of a diabetic mother
18.3
45.9
38
21
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
13.8
43.8
42
31
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
6.6
43.2
73
115
Z38.3
ICD-10 Finland
Twin, born in hospital
93.7
33.5
37
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
171.5
32.5
34
*
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
5.9
32.3
61
107
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
48.1
31.3
38
8
E34.31
ICD-10 Finland
Short stature, prenatal disorder
10.1
30.0
35
35
WX730
NOMESCO Finland
Conventional respirator
8.8
28.0
36
41
R4110
NOMESCO Finland
Physiotherapy
2.4
27.7
262
1299
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
25.9
25
*
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
8.7
25.4
33
38
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
7.4
25.4
38
52
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
25.0
222
1064
A11JC
ATC
Vitamins, other combinations
30.2
24.8
33
11
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
24.5
133
500
WX882
NOMESCO Finland
High dependency care
2.8
24.2
136
521
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
24.1
146
581
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.4
22.3
192
902
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
4.2
22.2
62
152
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.8
21.9
69
185
XG413
NOMESCO Finland
Spirometry with oscillometry
4.7
20.7
50
109
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
20.7
20
*
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
57.2
19.7
23
*
Z3226
NOMESCO Finland
Physiotherapist
2.2
19.6
224
1178
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
18.9
103
386
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.2
18.7
202
1036
R62.0
ICD-10 Finland
Delayed milestone
2.9
18.4
91
323
Z2446
NOMESCO Finland
Social worker
2.2
18.1
183
913
P07.0
ICD-10 Finland
Extremely low birth weight
+∞
17.6
17
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
16.6
297
1816
P08.1
ICD-10 Finland
Other heavy for gestational age infants
+∞
16.5
16
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
15.8
140
659
RK312, ,
NOMESCO Finland
13.5
15.8
27
20
FDE00
NOMESCO Finland
Closure of patent ductus arteriosus
157.9
15.3
16
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
15.1
233
1347
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
15.0
145
706
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
4.3
14.6
38
88
P22.8
ICD-10 Finland
Other respiratory distress of newborn
13.1
14.5
25
19
A03FA02
ATC
cisapride; oral, rectal
3.4
14.1
51
150
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
14.0
254
1544
P28.4
ICD-10 Finland
Other apnoea of newborn
29.7
13.7
18
6
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.1
13.6
29
57
Z2221
NOMESCO Finland
Medical doctor
1.9
13.2
212
1235
RT150, ,
NOMESCO Finland
4.2
13.1
35
83
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
12.9
208
1213
ZXE00
NOMESCO Finland
One hour or less
1.7
12.5
314
2089
RK520, ,
NOMESCO Finland
15.2
12.4
20
13
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.3
11.7
92
409
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.1
11.6
48
154
TJF80
NOMESCO Finland
Ostomy education
5.6
11.5
22
39
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.8
11.4
35
92
6BB16, ,
NOMESCO Finland
22.5
11.4
16
7
137
Kela drug reimbursment
Uraemia requiring dialysis
5.8
11.3
21
36
WX732
NOMESCO Finland
High frequency respirator
117.8
11.3
12
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
11.1
68
270
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
10.9
151
834
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.1
10.9
30
73
P52.0
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 1, of fetus and newborn
42.6
10.8
13
*
RS220, ,
NOMESCO Finland
3.6
10.8
35
96
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.4
10.7
27
61
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
10.7
326
2260
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
10.7
69
281
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3.0
10.6
46
152
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
58.9
10.5
12
*
Z3231
NOMESCO Finland
Registered nurse
1.6
10.3
305
2094
KAC00
NOMESCO Finland
Nephrectomy
5.5
10.3
20
36
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
10.2
163
942
XA800
NOMESCO Finland
Neuropsychological investigation
2.2
10.1
90
422
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.9
10.1
22
44
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
10.4
10.1
19
18
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
10.4
10.1
19
18
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
9.6
28
71
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.4
9.6
24
54
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.0
9.5
27
67
XKC03
NOMESCO Finland
Water cystometry
4.8
9.4
21
43
P61.2
ICD-10 Finland
Anaemia of prematurity
+∞
9.3
9
*
P01.11
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes more than 7 days before delivery
+∞
9.3
9
*
ZXD05
NOMESCO Finland
Urgent procedure
1.8
9.3
167
998
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.2
9.3
81
377
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.1
9.2
86
411
P03.4
ICD-10 Finland
Fetus and newborn affected by caesarean delivery
12.1
9.2
16
13
RL140, ,
NOMESCO Finland
3.7
9.2
29
78
H01AC01
ATC
somatropin; parenteral
2.7
9.0
47
172
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.0
8.9
96
484
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
2.5
8.8
58
239
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.2
8.7
23
54
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
8.5
243
1637
WW500
NOMESCO Finland
Blood transfusion
2.8
8.5
41
144
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.4
8.5
21
47
ZXA10
NOMESCO Finland
Bilateral
1.8
8.4
141
823
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.0
8.4
100
523
K40.2
ICD-10 Finland
Bilateral inguinal hernia, without obstruction or gangrene
8.8
8.4
17
19
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
8.4
90
454
R03BB04
ATC
tiotropium bromide; inhalant
4.1
8.3
23
56
P02.1
ICD-10 Finland
Fetus and newborn affected by other forms of placental separation and haemorrhage
19.6
8.3
12
6
P36.3
ICD-10 Finland
Sepsis of newborn due to other and unspecified staphylococci
88.1
8.3
9
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
8.3
89
448
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
7.2
8.3
19
26
ZX114
NOMESCO Finland
Intramuscular
3.4
8.1
29
85
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.0
149
895
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.4
8.0
18
24
UGC02
NOMESCO Finland
Rigid bronchoscopy
3.9
8.0
23
58
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
8.0
7.9
17
21
J45.8
ICD-10 Finland
Mixed asthma
3.0
7.9
34
112
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
7.9
124
710
Z2445
NOMESCO Finland
Psychologist
1.8
7.8
121
689
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
3.6
7.8
25
68
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.2
7.7
63
285
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
7.6
154
947
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.9
7.6
36
125
301
Kela drug reimbursment
Growth hormone
3.5
7.6
26
74
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.6
182
1171
P00.8
ICD-10 Finland
Fetus and newborn affected by other maternal conditions
14.7
7.6
12
8
R03AK08
ATC
formoterol and beclometasone; inhalant
3.5
7.5
25
70
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.5
223
1512
P29.31
ICD-10 Finland
Persistent fetal circulation
11.6
7.4
13
11
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.9
7.4
101
553
UDC00
NOMESCO Finland
Ear microscopy
1.9
7.3
90
475
P77
ICD-10 Finland
Necrotizing enterocolitis of fetus and newborn
78.3
7.3
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.3
153
949
SPAT1229
SPAT
Assessment of need for aid
4.2
7.2
19
45
WX725
NOMESCO Finland
Noninvasive ventilation
2.9
7.1
32
108
JF2AB
NOMESCO Finland
Colongraphy with X-ray
15.4
7.1
11
7
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
7.0
97
534
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
6.9
61
285
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
6.9
42
167
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
6.8
6.8
16
23
A11CC03
ATC
alfacalcidol; systemic
3.0
6.8
29
95
R03BA02
ATC
budesonide; inhalant
1.7
6.8
146
911
J21.90
ICD-10 Finland
Acute obstructive bronchitis in children
2.0
6.8
69
341
UKC02
NOMESCO Finland
Cystoscopy
2.7
6.7
36
134
EMB30
NOMESCO Finland
Adenotomy
1.6
6.7
181
1197
H66.9
ICD-10 Finland
Otitis media, unspecified
1.5
6.7
252
1796
RK410, ,
NOMESCO Finland
16.3
6.6
10
6
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.6
179
1183
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
6.6
94
521
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.1
6.6
64
311
7AA02, ,
NOMESCO Finland
22.0
6.6
9
*
P21.1
ICD-10 Finland
Mild and moderate birth asphyxia
4.0
6.5
18
44
Z99.2
ICD-10 Finland
Dependence on renal dialysis
6.3
6.5
16
25
P21.0
ICD-10 Finland
Severe birth asphyxia
5.8
6.5
17
29
A12AA04
ATC
calcium carbonate; oral
3.8
6.4
19
49
RS121, ,
NOMESCO Finland
3.4
6.4
22
63
WX704
NOMESCO Finland
Intubation
2.2
6.4
53
242
RK310, ,
NOMESCO Finland
6.7
6.4
15
22
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
6.4
72
370
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.5
6.3
39
156
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.3
209
1445
F83
ICD-10 Finland
Mixed specific developmental disorders
2.1
6.3
61
296
N18.8
ICD-10 Finland
Other chronic renal failure
4.1
6.3
17
41
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
6.3
142
898
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.6
6.2
20
55
F80.1
ICD-10 Finland
Expressive language disorder
2.4
6.2
42
176
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.6
6.2
162
1062
ZXA00
NOMESCO Finland
Right side
1.8
6.2
89
496
ZX108
NOMESCO Finland
Inhalation
3.5
6.1
21
60
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
3.5
6.1
21
60
FM2CE, ,
NOMESCO Finland
1.9
6.1
78
418
WW200
NOMESCO Finland
Immunization
2.8
6.0
29
102
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
6.0
61
301

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
144
863
1.75
7.83
5.3
3.5
21.19
21.69
%
0.14
139
836
150
935
1.68
7.03
5.2
3.3
2.64
2.60
g/l
0.38
143
896
213
1464
1.55
6.65
23.2
9.9
7.40
7.41
ph
2.67
188
1176
206
1407
1.56
6.61
18.3
12.3
1.40
1.33
mmol/l
2.34
200
1341
213
1466
1.55
6.60
23.4
10.0
5.14
4.99
kpa
2.39
207
1425
26
82
3.14
6.51
3.1
2.5
—
—
—
0
0
160
1039
1.61
6.35
5.1
3.3
13.77
14.09
umol/l
0.20
153
1005
198
1364
1.53
6.05
3.6
3.9
—
—
—
0
0
187
1273
1.55
6.03
23.0
9.8
—
—
—
0
0
228
1623
1.50
5.96
4.0
3.9
—
—
—
0
0
193
1350
1.50
5.44
22.8
9.8
9.54
9.76
kpa
0.84
186
1313
151
1041
1.50
4.51
3.0
5.1
1.58
1.67
mg/l
0.10
99
716
95
591
1.63
4.46
14.4
8.9
52.13
51.23
ng/l
0.11
95
579
358
2884
1.36
4.38
26.2
14.5
1.23
1.23
mmol/l
0.01
345
2775
133
906
1.50
4.20
1.6
1.5
162.88
428.31
u/ml
1.78
120
859
130
882
1.51
4.19
24.1
15.4
5.76
5.14
mmol/l
1.45
125
866
68
398
1.71
4.03
10.2
8.6
324.04
448.87
mg/l
0.39
52
314
33
152
2.15
3.97
2.4
2.0
—
—
—
0
0
138
959
1.47
3.95
18.0
13.8
0.80
0.81
mmol/l
0.71
133
931
17
58
2.88
3.80
1.0
1.0
—
—
—
0
0
31
142
2.16
3.79
5.3
5.5
2.76
2.21
ug/l
0.65
31
142
28
123
2.25
3.79
3.1
2.5
—
9.53
—
0
7
375
3092
1.32
3.74
24.9
12.7
1.23
1.23
mmol/l
0.09
351
2896
106
708
1.52
3.68
26.5
21.7
1.15
1.04
mg/l
2.23
106
697
27
119
2.24
3.63
1.6
1.3
—
—
—
0
0
10
20
4.89
3.59
1.2
1.5
3.59
3.92
mg/l
—
10
14
142
1012
1.43
3.55
4.4
7.7
31.33
31.07
s
0.18
142
1002
6
6
9.75
3.43
7.2
5.5
220.33
189.67
mg/l
—
6
6
93
617
1.52
3.34
15.8
16.0
106.34
105.70
mmol/l
0.90
93
617
16
57
2.75
3.33
10.4
3.2
130.00
158.55
umol/l
0.59
11
27
399
3366
1.29
3.19
12.0
8.5
5.95
5.91
mmol/l
0.08
374
3175
47
269
1.73
3.06
18.5
9.9
23.07
23.12
mmol/l
0.05
47
260
80
525
1.53
3.03
3.0
2.0
186.48
159.02
u/ml
0.26
40
245
153
1138
1.37
2.98
4.1
4.3
—
—
—
0
0
64
405
1.58
2.86
1.7
1.3
—
—
—
0
0
176
1349
1.33
2.82
16.8
13.2
—
—
—
0
0
17
70
2.38
2.70
3.2
3.5
—
—
—
0
0
29
149
1.92
2.68
10.2
5.8
—
—
—
0
0
138
1030
1.36
2.63
1.6
1.5
20.19
18.32
nmol/l
0.86
121
933
21
97
2.13
2.58
4.3
5.2
0.43
0.74
index
1.04
21
97
93
652
1.43
2.56
2.0
1.9
—
—
—
0
0
273
2246
1.26
2.54
8.6
8.7
31.41
20.72
umol/l
2.50
251
2081
12
43
2.73
2.50
7.3
4.3
-0.43
0.37
mmol/l
—
6
29
36
207
1.72
2.36
3.8
4.0
6.46
7.19
index
0.10
24
129
40
237
1.67
2.36
2.9
2.1
—
—
—
0
0
40
237
1.67
2.36
2.9
2.1
—
—
—
0
0
40
237
1.67
2.36
2.9
2.1
—
—
—
0
0
40
237
1.67
2.36
2.9
2.1
—
—
—
0
0
167
1304
1.30
2.33
6.5
4.2
7.38
7.38
ph
0.03
115
876
56
362
1.53
2.32
4.0
2.3
109.17
99.83
au/ml
0.19
18
152
291
2433
1.24
2.31
8.4
8.5
—
—
—
0
0
66
443
1.48
2.30
7.7
5.4
0.64
0.32
%
0.52
29
155
68
460
1.47
2.28
8.4
6.1
0.07
0.02
%
0.49
27
140
181
1435
1.28
2.25
6.4
5.2
1.11
1.14
inr
0.31
152
1199
94
677
1.39
2.24
4.4
5.8
67.19
64.79
e9/l
0.15
67
396
192
1534
1.28
2.24
4.3
2.9
2.40
2.40
mmol/l
0.09
183
1431
109
806
1.36
2.22
7.5
8.0
5.93
6.03
umol/l
0.05
93
672
177
1402
1.28
2.21
6.5
3.7
6.36
7.25
e6/l
0.41
155
1261
68
463
1.46
2.21
8.3
6.0
0.84
0.45
%
0.48
31
158
356
3056
1.22
2.18
10.3
11.1
—
—
—
0
0
78
549
1.42
2.13
1.5
1.5
557.10
13758149.65
pmol/l
0.50
69
487
22
112
1.93
2.13
10.6
7.5
1.54
1.46
mmol/l
0.07
12
53
57
380
1.49
2.07
15.6
17.4
-0.79
-0.41
mmol/l
0.34
48
308
238
1973
1.24
2.01
13.0
9.1
37.37
38.43
g/l
1.94
233
1880
185
1493
1.26
1.98
15.4
11.3
0.99
1.00
mmol/l
0.03
155
1220
434
3825
1.21
1.97
12.6
12.3
0.00
0.01
e9/l
0.79
349
2958
186
1505
1.25
1.95
16.0
11.3
7.37
7.37
ph
0.66
135
1032
115
876
1.32
1.93
2.2
1.8
—
—
—
0
0
57
386
1.46
1.93
15.6
17.3
7.41
7.38
ph
1.72
22
125
18
89
1.98
1.91
1.1
1.2
—
—
—
0
0
43
275
1.54
1.91
6.0
7.2
203.14
220.33
ng/l
0.07
35
252
19
96
1.94
1.90
4.9
2.8
36.84
35.29
mmol/l
0.10
19
96
5
11
4.42
1.89
3.8
4.0
0.42
0.49
umol/l
—
5
11
414
3643
1.20
1.88
8.7
6.3
134.95
114.47
u/l
3.50
401
3452
32
485
0.62
1.87
1.2
1.1
5.36
11.26
u/ml
1.62
21
307
185
1506
1.24
1.83
15.7
11.2
5.74
5.82
kpa
0.81
180
1475
22
119
1.81
1.81
1.1
1.3
10.82
2.80
u/ml
1.01
11
75
708
6581
1.28
1.81
12.7
8.3
—
—
—
0
0
264
2234
1.21
1.80
4.0
3.7
—
—
estimate
—
0
0
87
647
1.34
1.74
2.5
2.3
5.98
6.02
u/l
0.02
63
400
63
445
1.40
1.73
8.8
6.0
0.11
0.04
%
0.36
27
139
177
1444
1.24
1.72
14.6
11.1
5.14
5.09
kpa
0.16
171
1420
21
345
0.58
1.71
1.0
1.0
—
—
—
0
0
47
315
1.47
1.70
1.6
1.8
—
—
—
0
0
52
696
0.71
1.66
1.2
1.2
4.48
3.22
u/ml
0.23
41
493
163
1325
1.24
1.64
5.5
3.5
551.71
595.00
mosm/kgh2o
1.24
139
1181
59
770
0.72
1.63
1.2
1.3
3.00
3.27
u/ml
0.05
45
528
78
577
1.34
1.62
2.6
2.4
8.31
6.74
iu/l
0.48
58
370
7
25
2.73
1.59
2.0
1.6
217.57
164.32
nmol/l
—
7
25
7
25
2.73
1.59
1.0
1.0
—
—
—
0
0
5
14
3.47
1.57
3.0
3.9
139.60
139.43
mmol/l
—
5
14
5
14
3.47
1.57
1.0
1.1
165.00
128.43
nmol/l
—
5
14
133
1063
1.25
1.56
2.5
1.7
—
—
—
0
0
44
297
1.46
1.55
17.8
15.8
119.75
121.69
g/l
0.24
44
291
53
371
1.41
1.55
4.3
2.3
—
—
—
0
0
42
283
1.46
1.50
19.1
22.2
0.69
0.70
%
0.16
42
283
31
446
0.66
1.47
1.1
1.1
1.53
0.76
u/ml
0.22
18
219
37
246
1.48
1.43
6.0
4.6
7.33
7.33
ph
0.04
31
195
35
486
0.68
1.40
1.5
1.4
—
—
—
0
0
38
519
0.70
1.39
1.1
1.1
5.58
6.60
u/ml
0.11
27
349
74
558
1.31
1.38
2.2
2.2
8.24
8.63
nmol/l
0.13
68
496
102
1202
0.80
1.35
1.6
2.0
—
—
—
0
0
16
87
1.80
1.34
11.2
5.4
1.25
1.37
%
0.33
16
77
138
1568
0.82
1.29
3.7
3.4
82.10
101.52
ug/g
0.65
110
1255
18
103
1.71
1.28
7.8
11.5
10.87
9.37
mg/l
0.48
18
97
47
335
1.38
1.27
11.5
16.2
0.67
0.61
%
0.59
47
335
8
35
2.23
1.24
1.4
1.7
1255.00
2051.34
ml
—
8
35
316
2792
1.16
1.23
6.0
3.7
69.05
66.70
nmol/l
0.86
301
2670
57
712
0.76
1.21
1.1
1.2
4.89
5.98
u/ml
0.29
41
521
14
76
1.80
1.19
10.1
5.3
0.99
0.93
%
0.21
14
66
43
306
1.38
1.19
1.4
1.6
1371.28
1013.65
nmol/l
1.61
35
240
56
699
0.76
1.19
1.1
1.2
0.39
1.30
u/ml
2.86
37
476
106
1224
0.82
1.17
1.6
2.0
—
—
—
0
0
138
1553
0.83
1.17
1.9
2.1
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
4.49
—
0
26
105
1212
0.82
1.16
1.6
2.0
—
—
—
0
0
432
3914
1.14
1.16
10.7
10.4
8.47
8.42
%
0.15
407
3763
16
92
1.70
1.14
20.4
8.9
6.01
6.63
pmol/l
0.19
16
92
21
308
0.65
1.13
1.1
1.1
4.98
8.11
eliau/ml
—
5
36
7
29
2.35
1.12
1.7
1.2
—
—
—
0
0
106
1218
0.82
1.12
1.6
2.0
—
—
—
0
0
15
85
1.72
1.12
2.1
2.5
—
—
—
0
0
20
123
1.59
1.12
1.1
1.1
—
—
—
0
0
461
4212
1.14
1.05
11.3
10.9
0.19
0.21
e9/l
1.14
403
3588
16
95
1.64
1.03
5.4
3.2
—
—
—
0
0
9
45
1.95
1.03
1.3
1.2
—
—
—
0
0
81
645
1.24
1.03
1.6
1.8
—
—
—
0
0
448
4095
1.13
0.99
10.8
10.1
0.60
0.56
e9/l
2.10
378
3428
428
3903
1.13
0.98
10.7
10.3
2.73
3.20
%
4.07
407
3757
253
2232
1.14
0.98
8.1
4.7
237.23
33.39
e6/l
0.47
201
1626
436
3981
1.13
0.98
10.6
10.0
48.59
49.50
%
0.73
418
3882
100
1139
0.83
0.98
1.6
2.0
—
—
—
0
0
10
52
1.87
0.98
1.3
1.2
—
—
—
0
0
0
29
0.00
0.97
0.0
3.3
—
289.41
—
0
29
13
74
1.71
0.97
1.2
1.1
—
—
—
0
0
12
67
1.75
0.96
2.3
2.3
—
—
—
0
0
447
4092
1.13
0.95
10.8
10.1
0.04
0.04
e9/l
0.02
377
3430
184
1591
1.15
0.95
4.2
2.5
—
—
—
0
0
86
987
0.83
0.92
1.6
2.1
—
—
—
0
0
15
91
1.61
0.91
2.9
2.2
—
—
—
0
0
74
860
0.82
0.90
1.7
2.5
—
—
—
0
0
232
2047
1.14
0.90
7.4
4.5
0.48
0.25
e6/l
0.35
180
1442
425
3889
1.12
0.89
10.8
10.4
0.60
0.63
%
0.47
405
3754
56
436
1.26
0.88
1.9
1.4
—
—
—
0
0
158
1359
1.16
0.88
6.1
4.1
3.19
3.31
e6/l
0.04
96
697
8
42
1.85
0.87
22.6
14.1
716.88
763.57
nmol/l
—
8
42
442
4059
1.12
0.86
10.6
10.2
36.40
35.25
%
1.12
422
3937
11
62
1.73
0.86
1.1
1.3
101.55
127.37
pmol/l
0.84
11
62
15
93
1.57
0.84
2.3
4.1
3.62
4.19
%
—
5
35
25
174
1.40
0.83
2.3
2.7
—
—
—
0
0
175
1525
1.14
0.82
1.9
1.6
99.55
97.63
pmol/l
0.19
80
818
15
217
0.66
0.81
1.9
5.1
—
—
—
0
0
56
442
1.24
0.80
5.7
3.9
—
—
—
0
0
10
56
1.74
0.80
1.0
1.1
—
—
—
0
0
23
159
1.41
0.80
6.7
4.9
434.22
444.62
umol/l
0.10
23
149
14
205
0.66
0.80
1.1
1.3
1.86
20.70
u/ml
—
9
164
6
32
1.82
0.79
1.5
4.6
12.83
32.59
u/l
—
6
32
24
168
1.40
0.78
1.8
1.3
344.38
377.94
ug/g
0.37
16
84
176
1544
1.13
0.75
4.9
2.9
0.00
0.02
estimate
0.50
46
447
35
431
0.78
0.73
1.2
1.3
3.08
2.89
mmol/l
0.56
17
247
213
1894
1.12
0.73
4.1
3.3
2.60
2.53
mg/l
0.19
196
1701
10
58
1.68
0.72
15.9
11.2
1.26
1.24
mmol/l
—
10
52
68
556
1.20
0.71
4.1
4.7
64.10
107.72
mg/l
0.62
62
469
51
405
1.23
0.71
1.2
1.3
259.55
215.68
miu/ml
0.43
26
183
86
959
0.85
0.69
1.3
1.3
—
46.30
—
0
8
155
1356
1.13
0.69
5.9
4.0
0.85
0.94
e6/l
0.11
91
695
48
380
1.24
0.69
1.0
1.0
9.54
8.69
mu/l
0.32
43
329
5
26
1.87
0.69
3.2
3.8
5.22
4.49
mmol/l
—
5
26
21
148
1.38
0.68
2.2
4.6
—
—
—
0
0
469
4356
1.10
0.67
13.1
11.8
3.44
3.48
e9/l
0.13
396
3622
34
259
1.28
0.67
6.3
3.5
—
—
—
0
0
15
206
0.70
0.65
1.5
1.3
0.64
2.05
u/ml
—
10
143
45
527
0.82
0.63
2.0
1.4
—
—
—
0
0
291
2650
1.10
0.63
9.6
5.7
41.43
56.06
e6/l
0.38
207
1717
451
4194
1.09
0.61
10.8
10.1
2.50
2.34
e9/l
1.56
393
3617
66
548
1.18
0.61
4.6
5.1
190.74
7.10
mg/mmol
0.49
60
453
0
20
0.00
0.60
0.0
3.5
—
13.70
—
0
20
0
21
0.00
0.60
0.0
2.6
—
—
—
0
0
0
22
0.00
0.59
0.0
3.4
—
30.45
—
0
22
37
291
1.24
0.58
1.0
1.0
3.03
3.30
kpa
0.64
31
245
10
62
1.57
0.58
19.8
10.4
1.24
1.23
mmol/l
—
10
57
8
52
1.50
0.57
1.4
1.5
—
—
—
0
0
8
52
1.50
0.57
1.4
1.5
—
—
—
0
0
8
52
1.50
0.57
1.4
1.5
—
—
—
0
0
24
180
1.30
0.55
2.1
1.9
2.35
3.58
iu/l
0.71
12
77
37
294
1.23
0.54
1.0
1.0
-1.25
-2.57
mmol/l
—
10
69
37
294
1.23
0.54
1.0
1.0
—
—
—
0
0
37
294
1.23
0.54
1.0
1.0
7.37
7.24
kpa
0.15
31
248
622
5885
1.10
0.53
22.7
13.5
3.97
3.91
mmol/l
3.62
608
5714
10
64
1.52
0.52
1.0
1.1
266.50
283.33
mg/l
—
10
64
13
89
1.42
0.51
2.1
1.9
26.13
21.37
mg/l
—
8
47
190
1714
1.10
0.50
6.3
4.8
7.89
8.94
mmol/l
1.56
180
1626
622
5893
1.09
0.49
22.7
13.6
139.45
139.49
mmol/l
0.22
611
5751
241
2202
1.09
0.48
1.7
1.6
—
—
—
0
0
653
6203
1.09
0.47
11.5
9.7
26.87
24.83
u/l
0.84
637
6028
15
193
0.75
0.47
1.7
1.6
—
—
—
0
0
7
47
1.45
0.46
1.1
1.3
—
—
—
0
0
21
256
0.79
0.45
1.4
1.2
—
—
—
0
0
33
266
1.21
0.44
1.6
2.0
1.90
7.48
iu/ml
—
5
49
31
249
1.21
0.43
19.5
21.3
15.97
15.74
%
0.16
31
242
5
30
1.62
0.43
3.2
1.4
—
—
—
0
0
229
2342
0.93
0.43
2.3
2.4
—
—
—
0
0
126
1125
1.10
0.43
1.6
1.7
—
—
—
0
0
216
1977
1.08
0.42
4.1
3.0
—
0.25
—
0
8
384
3853
0.94
0.41
7.4
4.1
517.85
246.31
e6/l
0.23
13
52
47
523
0.86
0.41
1.9
2.6
—
—
—
0
0
28
224
1.22
0.41
1.4
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
2.8
—
—
—
0
0
5
33
1.47
0.40
1.0
1.9
6.93
4.57
mmol/24h
—
5
33
780
7489
1.15
0.40
23.6
17.6
86.17
86.28
fl
0.24
768
7397
7
98
0.69
0.40
1.1
1.1
—
—
—
0
0
328
3056
1.07
0.38
6.0
3.7
0.00
0.00
estimate
-0.00
55
560
9
64
1.37
0.38
1.1
1.1
—
—
—
0
0
674
6430
1.08
0.38
22.1
16.5
13.23
13.07
%
2.77
660
6333
103
918
1.10
0.37
2.6
2.3
12.25
49.89
ng/l
2.15
51
290
15
185
0.78
0.37
1.0
1.0
0.84
0.80
g/l
0.28
15
185
780
7493
1.14
0.37
23.6
17.6
28.99
28.99
pg
0.00
768
7401
780
7493
1.14
0.37
23.7
17.6
4.67
4.63
e12/l
1.18
754
7156
409
3842
1.06
0.37
4.7
3.7
48.55
54.36
ug/l
0.38
396
3692
780
7494
1.13
0.36
25.0
19.0
40.03
40.27
%
0.21
768
7401
6
40
1.46
0.36
1.0
1.1
—
—
nmol/l
—
0
0
24
279
0.83
0.36
1.7
4.1
3.14
3.33
mmol/l
0.50
24
269
5
76
0.64
0.35
1.0
1.1
—
—
—
0
0
15
184
0.79
0.35
1.0
1.0
1.44
1.49
g/l
0.41
15
184
159
1636
0.93
0.35
5.2
2.9
1.06
2.09
kg/l
0.47
104
962
6
41
1.42
0.35
1.2
1.0
—
19.63
—
0
11
6
41
1.42
0.35
1.3
1.2
—
—
—
0
0
30
247
1.18
0.34
1.1
1.4
—
—
—
0
0
19
149
1.24
0.34
1.9
1.3
—
—
—
0
0
128
1326
0.92
0.34
1.3
1.3
—
—
—
0
0
10
129
0.75
0.34
1.1
1.3
4.65
8.01
u/ml
—
10
114
780
7498
1.13
0.33
24.0
18.0
134.93
133.72
g/l
1.46
769
7408
779
7488
1.12
0.33
23.8
17.7
275.78
271.73
e9/l
0.88
754
7169
95
851
1.09
0.32
2.7
2.3
—
—
—
0
0
373
3507
1.06
0.31
3.5
2.7
1.12
1.07
mmol/l
0.87
361
3345
14
170
0.79
0.31
1.8
1.6
—
—
—
0
0
7
51
1.33
0.31
1.1
1.2
0.20
0.14
nmol/l
—
7
43
780
7501
1.12
0.31
23.7
17.6
6.99
6.93
e9/l
0.19
755
7161
14
169
0.80
0.30
1.7
1.5
—
—
—
0
0
8
103
0.75
0.29
1.0
1.1
—
—
—
0
0
155
1582
0.94
0.28
1.8
1.8
—
—
—
0
0
315
3149
0.95
0.28
1.8
1.9
3.56
3.23
u/ml
0.08
66
610
18
144
1.22
0.28
1.2
1.3
—
—
—
0
0
28
235
1.16
0.27
1.3
1.2
—
—
—
0
0
50
438
1.11
0.27
1.2
1.2
—
—
—
0
0
17
136
1.22
0.27
4.2
4.0
3.49
3.39
e9/l
0.09
17
136
65
685
0.91
0.27
1.2
1.2
2.09
6.77
u/ml
1.21
25
204
22
181
1.18
0.27
1.3
1.4
—
—
—
0
0
164
1514
1.06
0.26
2.0
2.0
1.27
1.17
mmol/l
0.75
151
1407
87
904
0.92
0.26
1.7
1.6
564.71
469.71
titre
0.12
17
140
277
2596
1.05
0.26
5.3
3.4
6.45
6.37
ph
0.53
129
1221
8
65
1.19
0.26
1.6
1.8
—
—
—
0
0
70
734
0.92
0.26
1.3
1.2
12.14
26.27
iu/ml
0.84
13
132
15
119
1.23
0.25
6.4
4.0
24.32
22.86
mmol/l
0.63
15
113
410
4059
0.96
0.24
2.9
2.4
5.35
5.28
mmol/l
0.54
378
3767
287
2699
1.05
0.24
2.8
2.2
—
—
—
0
0
74
667
1.08
0.23
4.1
2.5
3.88
4.21
e9/l
0.56
67
603
33
358
0.89
0.23
1.1
1.2
—
—
—
0
0
22
184
1.16
0.23
1.2
1.1
—
—
—
0
0
327
3086
1.04
0.23
6.0
3.7
0.00
2.25
estimate
0.50
56
547
39
418
0.90
0.23
2.3
1.9
0.00
0.04
estimate
0.80
11
110
160
1487
1.05
0.21
6.7
3.5
0.00
0.00
estimate
-0.00
54
525
590
5643
1.04
0.21
4.8
4.3
2.08
1.96
mu/l
1.37
564
5393
0
10
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.20
0.0
1.2
—
—
—
0
0
0
13
0.00
0.20
0.0
2.1
—
—
—
0
0
25
214
1.14
0.20
1.7
1.7
0.19
0.22
nmol/l
0.29
20
168
16
181
0.85
0.20
1.4
4.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
0.00
—
0
14
6
48
1.21
0.20
1.0
1.1
—
87.56
ng/l
—
0
9
33
353
0.90
0.19
1.0
1.1
—
—
—
0
0
326
3088
1.04
0.19
6.1
3.7
0.00
0.00
estimate
-0.00
56
547
95
968
0.94
0.18
1.3
1.4
52.50
308.89
titre
—
6
44
139
1294
1.05
0.18
1.7
1.6
—
—
—
0
0
7
56
1.21
0.18
14.0
3.7
4.93
5.01
kpa
—
7
56
7
60
1.13
0.17
2.3
1.3
52.29
41.22
pmol/l
—
7
55
688
6614
1.05
0.17
20.1
15.8
335.53
334.77
g/l
1.22
681
6555
5
64
0.76
0.17
1.0
1.2
—
—
—
0
0
28
299
0.90
0.16
1.2
1.2
—
—
—
0
0
25
268
0.90
0.16
1.7
4.4
—
—
—
0
0
26
278
0.90
0.16
1.8
4.3
47.60
11.01
e6/l
0.41
20
187
6
77
0.75
0.15
2.3
3.2
7.00
45.72
u/ml
—
6
67
366
3605
0.97
0.15
4.2
3.1
34.88
35.02
mmol/mol
0.10
348
3434
682
6654
0.96
0.15
17.0
11.9
21.20
23.19
mg/l
0.93
526
4780
19
206
0.89
0.14
1.1
1.1
6.16
18.10
u/ml
—
7
33
81
749
1.05
0.14
3.4
3.8
1752.74
1236.04
ng/l
0.24
42
393
8
94
0.82
0.14
2.0
1.6
—
—
—
0
0
14
119
1.14
0.12
1.1
1.1
—
—
—
0
0
41
422
0.94
0.12
1.7
1.9
6.10
6.35
ph
1.18
31
275
150
1415
1.03
0.11
2.0
1.8
—
—
—
0
0
39
355
1.07
0.11
1.6
1.7
—
—
—
0
0
60
555
1.05
0.11
1.9
2.5
23.37
29.31
u/l
2.26
52
444
220
2090
1.03
0.11
5.6
3.0
0.00
0.00
estimate
0.50
45
446
95
890
1.04
0.10
3.1
2.4
8925.90
7227.87
u/l
0.15
24
246
16
140
1.11
0.10
1.7
1.8
—
—
—
0
0
28
290
0.93
0.09
1.8
4.1
401.18
400.09
mg/l
0.00
28
285
5
45
1.08
0.09
3.2
2.8
3.58
3.82
mmol/l
—
5
45
5
46
1.05
0.09
1.6
2.2
—
—
—
0
0
5
59
0.82
0.08
3.8
2.5
22.48
17.86
umol/l
—
5
59
8
74
1.05
0.07
2.1
3.0
—
261.30
—
0
20
397
3879
0.98
0.07
3.6
2.9
2.59
2.55
mmol/l
0.51
380
3691
7
80
0.85
0.07
2.1
1.3
—
—
—
0
0
17
178
0.92
0.07
1.4
1.2
—
0.21
—
0
9
9
81
1.08
0.07
8.6
5.9
—
—
—
0
0
395
3859
0.98
0.07
3.6
2.8
1.35
1.40
mmol/l
2.38
378
3674
652
6344
0.98
0.07
15.3
10.9
58.93
59.80
umol/l
0.46
641
6244
32
295
1.05
0.07
3.0
3.1
51.99
53.15
%
0.21
32
295
8
89
0.87
0.07
1.1
1.1
191.25
201.62
mg/l
—
8
83
11
117
0.91
0.05
1.1
1.4
2.60
14.95
u/ml
2.75
11
106
11
97
1.10
0.05
1.0
1.2
—
—
—
0
0
21
215
0.94
0.05
1.5
1.7
9.66
5.67
ug/l
0.38
21
200
70
663
1.03
0.04
2.0
2.2
—
—
—
0
0
346
3330
1.01
0.04
4.7
4.6
28.09
25.09
u/l
0.81
329
3211
10
88
1.10
0.04
2.0
1.8
0.86
0.74
ug/l
—
10
70
159
1522
1.02
0.04
8.0
5.2
—
—
—
0
0
19
175
1.05
0.03
1.8
2.1
—
—
—
0
0
71
676
1.02
0.03
1.5
1.3
267.45
151.35
u/ml
0.77
20
204
66
628
1.02
0.03
1.5
1.5
—
—
—
0
0
12
124
0.94
0.02
2.6
2.6
3.59
5.23
u/ml
—
5
54
12
109
1.07
0.02
1.0
1.0
—
—
—
0
0
15
138
1.05
0.02
2.9
2.6
1.13
2.08
mmol/l
—
10
111
18
167
1.05
0.02
1.2
1.1
—
—
—
0
0
408
3941
1.01
0.02
3.7
3.0
4.23
4.26
mmol/l
0.28
391
3778
20
201
0.96
0.01
2.7
2.1
0.00
0.01
estimate
—
8
86
36
343
1.02
0.00
1.3
1.2
—
—
—
0
0
11
112
0.95
0.00
1.7
1.5
10.35
7.07
u/l
0.31
11
98
14
137
0.99
0.00
1.1
1.1
—
—
—
0
0
10
93
1.04
0.00
1.0
1.2
—
—
—
0
0
303
2934
1.00
0.00
1.9
1.8
1.62
1.54
g/l
0.66
168
1637
24
233
1.00
0.00
1.2
1.3
—
—
—
0
0
31
296
1.02
0.00
1.5
1.3
—
—
—
0
0
37
360
1.00
0.00
2.1
1.6
0.11
0.16
mg/l
—
10
144
31
297
1.01
0.00
1.4
1.3
—
—
—
0
0
19
179
1.03
0.00
14.9
24.7
11.84
11.36
%
0.28
19
179
5
49
0.99
0.00
1.2
1.1
—
—
—
0
0
5
49
0.99
0.00
1.2
1.1
207.20
245.78
iu/ml
—
5
49
5
49
0.99
0.00
1.2
2.4
104.40
97.12
g/l
—
5
49
6
62
0.94
0.00
2.5
2.4
1175.67
1039.66
u/ml
—
6
62
9
90
0.97
0.00
1.1
1.1
20.91
33.42
iu/ml
—
9
90
5
50
0.97
-0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
85.33
—
0
6
8
80
0.97
-0.00
1.5
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
37.21
—
0
7
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
330.60
—
0
5
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
531
5141
1.00
-0.00
4.1
3.7
14.60
14.43
pmol/l
0.88
481
4591
8
80
0.97
-0.00
1.1
1.0
—
—
—
0
0
7
73
0.93
-0.00
1.1
1.7
12.33
8.72
umol/l
—
7
73
0
8
0.00
-0.00
0.0
1.4
—
883.88
—
0
8
5
53
0.91
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
35.60
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.95
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
5.41
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
1343.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED and mortality.

Females

Parameter HR [95% CI] p-value
P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED 3.516 [2.95, 4.19] < 0.001
Birth year 0.994 [0.99, 1.0] 0.206

During the follow-up period (1.1.1998 — 31.12.2019), 183 out of 21756 females with P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED died.

Males

Parameter HR [95% CI] p-value
P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED 2.27 [1.96, 2.63] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 236 out of 25440 males with P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED died.

Mortality risk

Mortality risk for people of age

years, who have P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED.

N-year risk Females Males
1 0.389% 0.476%
5 2.249% 2.702%
10 5.077% 6.732%
15 10.073% 12.848%
20 16.689% 20.649%

Relationships between endpoints

Index endpoint: P16_DISORD_RELATED_GESTATION_LOW_BIRTHWGHTT_NECIFIED – Disorders related to short gestation and low birth weight, not elsewhere classified

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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