Neonatal jaundice from other and unspecified causes

P16_NEONTAL_JAUND_OTH_UNSP_CAUSES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P59
  • Cause of death: ICD-10 P59

2 out of 7 registries used, show all original rules.

558

4. Check minimum number of events

None

558

5. Include endpoints

None

558

6. Filter based on genotype QC (FinnGen only)

497

Control definitions (FinnGen only)

Control exclude
P16_HAEMORRHAGIC_HAEMATOL_DISORD_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P[5-6]
Name in latin
Icterus neonatalis ex causis aliis et non specificatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54258 22632 31624
Only index persons 20837 8616 12221
Unadjusted period prevalence (%)
Whole population 0.79 0.65 0.88
Only index persons 0.40 0.32 0.47
Median age at first event (years)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01

-FinnGen-

Key figures

All Female Male
Number of individuals 497 259 238
Unadjusted period prevalence (%) 0.10 0.09 0.11
Median age at first event (years) 0.01 0.01 0.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
530
Matched controls
5128
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3866.4
307.7
320
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
+∞
229.1
205
*
P07.3
ICD-10 Finland
Other preterm infants
20.0
216.3
199
150
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
7.1
65.6
114
190
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
10.6
28.1
32
31
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
5.5
25.6
53
102
P59.3
ICD-10 Finland
Neonatal jaundice from breast milk inhibitor
+∞
22.8
22
*
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
5.8
17.0
32
56
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
11.9
15.4
28
24
WX722
NOMESCO Finland
PEEP
4.0
14.4
42
107
P59.8
ICD-10 Finland
Neonatal jaundice from other specified causes
+∞
12.4
12
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
11.5
60
221
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
4.4
9.9
25
57
602
Kela drug reimbursment
Children's severe malnutrition
2.7
8.4
47
179
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
6.2
7.9
20
32
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.6
7.6
18
39
A03FA02
ATC
cisapride; oral, rectal
3.6
7.3
24
67
P22.8
ICD-10 Finland
Other respiratory distress of newborn
7.2
7.1
16
22
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
8.7
6.9
14
16
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
6.8
125
758
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
10.8
6.7
12
11
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
4.3
6.7
17
39
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
2.9
6.6
31
108
WX882
NOMESCO Finland
High dependency care
1.9
6.6
83
447
P07.2
ICD-10 Finland
Extreme immaturity
8.6
6.4
13
15
A11JC
ATC
Vitamins, other combinations
6.1
6.3
16
26
JKD50
NOMESCO Finland
Hepatoportoenterostomy
10.8
6.2
11
10
Q44.29
ICD-10 Finland
Atresia of bile ducts
10.8
6.2
11
10
P55.1
ICD-10 Finland
ABO isoimmunization of fetus and newborn
+∞
6.2
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
163
2.49
6.30
11.5
5.7
18.89
13.94
umol/l
0.48
40
146
18
54
3.30
4.92
2.7
2.2
—
—
—
0
0
92
569
1.68
4.58
19.9
8.4
9.82
5.88
umol/l
0.59
86
478
189
1415
1.45
3.97
20.8
9.7
47.58
24.99
umol/l
3.55
181
1306
14
46
3.00
3.35
2.1
2.4
—
—
—
0
0
8
22
3.56
2.29
1.6
3.5
58.00
29.27
u/l
—
8
22
92
672
1.39
2.11
8.3
6.3
1.14
2.08
mg/l
1.65
69
489
95
703
1.37
2.02
2.0
1.9
—
—
—
0
0
7
20
3.42
1.99
1.6
1.2
—
—
—
0
0
47
305
1.54
1.97
1.7
1.3
—
—
—
0
0
16
75
2.10
1.94
1.1
1.3
12.40
3.23
u/ml
—
10
44
10
38
2.58
1.92
5.3
3.7
—
—
—
0
0
308
2687
1.26
1.86
15.6
13.0
0.00
0.01
e9/l
0.78
232
2024
17
84
1.99
1.82
3.6
3.0
44.19
35.27
mmol/l
0.58
17
84
20
105
1.88
1.81
3.3
2.1
—
—
—
0
0
9
34
2.59
1.79
1.9
2.7
—
—
—
0
0
9
34
2.59
1.79
1.0
1.1
—
—
—
0
0
44
289
1.52
1.77
11.6
5.3
0.28
0.42
%
0.47
16
108
45
300
1.49
1.70
12.8
6.0
0.13
0.02
%
0.60
16
94
8
30
2.60
1.66
5.4
2.0
32.87
31.77
pg
—
8
30
72
532
1.36
1.56
6.5
5.8
70.37
61.44
e9/l
0.89
45
307
56
397
1.41
1.55
10.2
7.1
268.27
282.21
umol/l
0.56
56
381
6
21
2.78
1.45
1.8
1.7
—
1.08
—
0
5
44
304
1.44
1.42
3.6
9.9
260.36
334.10
mg/l
0.24
33
259
5
16
3.04
1.39
1.6
2.6
—
—
—
0
0
255
2227
1.21
1.37
14.4
11.5
—
—
—
0
0
53
382
1.38
1.36
2.5
2.2
130.41
165.15
u/ml
0.56
30
164
21
124
1.66
1.34
2.3
1.3
342.36
377.59
ug/g
0.34
14
68
40
275
1.44
1.33
3.1
2.6
85.20
92.54
au/ml
0.15
15
125
14
74
1.85
1.28
1.1
1.1
—
—
—
0
0
307
2740
1.20
1.27
14.0
10.7
46.25
48.04
%
1.57
299
2667
313
2800
1.20
1.26
14.1
10.9
38.00
36.29
%
1.74
302
2712
16
89
1.76
1.26
1.3
1.4
—
—
—
0
0
11
54
1.99
1.23
1.0
1.2
—
—
—
0
0
314
2818
1.19
1.19
13.2
10.8
0.61
0.56
e9/l
1.79
258
2295
5
19
2.56
1.17
13.4
4.0
108.00
106.14
mmol/l
—
5
14
5
19
2.56
1.17
13.4
4.0
10.60
12.29
mmol/l
—
5
14
43
308
1.38
1.16
13.1
5.9
0.33
0.56
%
0.49
15
113
0
35
0.00
1.14
0.0
1.1
—
—
—
0
0
453
4218
1.27
1.14
25.6
18.5
13.28
13.10
%
1.99
444
4164
41
293
1.38
1.13
13.5
6.0
0.00
0.05
%
0.64
12
98
313
2816
1.18
1.12
13.3
10.8
0.04
0.04
e9/l
1.46
257
2297
5
20
2.43
1.11
1.2
1.4
3.89
4.30
mg/l
—
5
15
302
2716
1.18
1.07
14.3
11.0
8.42
8.47
%
0.13
287
2605
91
734
1.24
1.06
2.0
1.7
—
—
—
0
0
6
121
0.47
1.06
1.5
1.7
—
3.30
—
0
26
29
197
1.45
1.06
1.6
1.7
—
—
—
0
0
317
2864
1.18
1.05
13.5
10.8
2.58
2.42
e9/l
1.31
268
2410
115
952
1.22
1.05
3.5
3.7
609.20
589.87
mosm/kgh2o
0.34
102
840
118
982
1.21
1.02
3.8
3.8
6.37
6.78
e6/l
0.11
106
878
418
3873
1.21
1.01
15.0
10.3
26.71
25.00
u/l
0.90
411
3755
15
88
1.67
1.01
4.5
4.1
1.61
4.45
%
—
7
39
94
766
1.23
1.00
6.5
4.6
—
—
—
0
0
5
22
2.21
0.99
1.0
1.2
—
—
—
0
0
319
2896
1.17
0.96
14.1
11.8
0.23
0.22
e9/l
0.27
272
2413
324
2948
1.16
0.93
16.5
12.6
3.31
3.33
e9/l
0.05
265
2399
38
278
1.35
0.93
3.2
2.5
—
—
—
0
0
299
2708
1.16
0.91
14.4
11.0
3.24
3.31
%
0.17
289
2600
255
2283
1.16
0.91
10.2
6.2
150.45
134.53
u/l
1.62
247
2156
104
870
1.19
0.86
3.0
2.9
0.00
0.00
estimate
-0.00
35
253
6
30
1.95
0.84
1.5
1.4
—
—
—
0
0
154
1335
1.16
0.83
1.6
1.6
—
—
—
0
0
11
63
1.70
0.82
1.0
1.0
—
—
—
0
0
297
2703
1.14
0.80
14.6
11.0
0.65
0.62
%
0.43
288
2607
232
2414
0.88
0.80
2.8
2.4
5.22
5.29
mmol/l
0.59
212
2210
15
95
1.54
0.78
4.7
6.9
7.39
7.39
ph
0.06
15
95
204
2138
0.88
0.77
2.1
2.0
2.76
3.76
u/ml
0.47
37
372
84
698
1.20
0.76
21.5
16.1
0.81
0.81
mmol/l
0.15
84
676
183
1619
1.14
0.75
3.4
3.6
6.35
6.38
ph
0.09
71
714
12
73
1.60
0.73
2.2
1.7
—
—
—
0
0
12
73
1.60
0.73
1.2
1.1
—
—
—
0
0
145
1264
1.15
0.73
4.3
3.7
2.46
2.51
mg/l
0.14
132
1144
17
113
1.47
0.73
5.9
4.7
—
—
—
0
0
77
638
1.20
0.72
1.8
1.9
—
—
—
0
0
11
66
1.63
0.71
8.0
9.2
6.04
5.42
pmol/l
0.25
11
66
16
220
0.69
0.70
1.1
1.1
—
—
—
0
0
33
249
1.30
0.69
3.4
3.8
—
—
—
0
0
211
1892
1.13
0.69
3.9
3.9
0.00
0.00
estimate
-0.00
41
327
114
980
1.16
0.69
4.6
4.5
3.60
2.46
e6/l
0.53
59
526
19
131
1.42
0.69
3.4
2.7
—
—
—
0
0
7
41
1.66
0.68
9.6
8.1
—
—
—
0
0
262
2384
1.13
0.67
4.3
4.0
730.22
238.42
e6/l
—
9
26
12
75
1.56
0.67
4.8
7.6
9.85
9.03
kpa
0.71
12
75
12
75
1.56
0.67
4.8
7.6
2.48
1.52
mmol/l
—
5
35
12
75
1.56
0.67
4.8
7.6
5.11
4.84
kpa
0.42
12
75
30
225
1.31
0.66
37.1
27.3
0.71
0.70
%
0.06
30
225
442
4159
1.17
0.66
11.3
8.7
—
—
—
0
0
38
452
0.80
0.64
1.3
1.2
11.43
14.65
iu/ml
—
10
77
77
646
1.18
0.64
1.5
1.5
258.91
416.61
u/ml
0.50
69
609
30
227
1.30
0.63
37.1
27.2
97.08
95.51
%
2.21
30
227
211
1903
1.12
0.62
3.9
3.9
0.00
3.89
estimate
0.50
42
316
10
61
1.60
0.61
8.0
2.6
—
—
—
0
0
87
742
1.16
0.60
1.6
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
2.3
—
1.44
—
0
14
13
86
1.47
0.58
1.1
1.1
—
—
—
0
0
43
345
1.22
0.57
1.0
1.0
8.16
8.77
mu/l
0.33
36
298
8
53
1.47
0.56
18.5
8.7
1.26
1.22
mmol/l
—
8
48
19
137
1.35
0.55
2.4
2.0
—
—
—
0
0
6
36
1.62
0.55
1.7
1.4
—
—
—
0
0
85
924
0.87
0.55
1.8
1.6
92.95
98.39
pmol/l
0.61
43
473
11
154
0.68
0.55
1.8
4.3
—
—
—
0
0
252
2309
1.11
0.54
16.5
10.5
5.95
5.96
mmol/l
0.02
241
2202
9
60
1.46
0.53
1.9
1.3
—
—
—
0
0
29
225
1.26
0.52
1.9
2.0
—
—
—
0
0
9
61
1.43
0.52
1.9
1.5
—
—
—
0
0
173
1557
1.11
0.52
5.4
5.0
18.35
23.20
e6/l
0.23
129
1155
26
199
1.28
0.52
3.3
2.2
—
—
—
0
0
26
199
1.28
0.52
3.3
2.2
—
—
—
0
0
26
199
1.28
0.52
3.3
2.2
—
—
—
0
0
26
199
1.28
0.52
3.3
2.2
—
—
—
0
0
9
62
1.41
0.51
1.9
1.4
—
—
—
0
0
9
62
1.41
0.51
1.4
1.1
—
—
—
0
0
9
62
1.41
0.51
1.1
1.0
—
—
—
0
0
210
1911
1.10
0.51
3.9
3.9
0.00
0.00
estimate
-0.00
41
320
46
521
0.84
0.50
4.7
4.3
425.39
1183.42
ng/l
2.59
26
298
7
44
1.55
0.49
10.9
3.3
1.00
1.23
mmol/l
—
7
36
27
210
1.26
0.48
2.8
3.7
0.19
0.12
e6/l
0.31
27
201
46
519
0.84
0.48
2.7
2.3
10.35
51.84
ng/l
1.49
22
181
200
2050
0.91
0.47
1.9
1.8
1.33
1.44
g/l
0.74
103
1069
98
859
1.13
0.47
3.2
3.7
0.00
0.00
estimate
-0.00
40
307
36
414
0.83
0.47
1.3
1.2
2.10
9.05
u/ml
1.05
11
113
20
246
0.78
0.47
1.1
1.3
—
—
—
0
0
209
2137
0.91
0.47
4.2
3.4
34.60
35.24
mmol/mol
0.42
199
2033
53
445
1.17
0.46
3.0
2.4
7283.20
9719.94
u/l
—
10
114
37
301
1.20
0.45
2.0
1.5
—
—
—
0
0
19
234
0.78
0.45
1.1
1.1
—
—
—
0
0
61
667
0.87
0.44
1.7
1.8
—
—
—
0
0
70
604
1.14
0.43
1.3
1.4
22.47
18.62
nmol/l
1.45
62
540
61
665
0.87
0.43
1.6
1.8
—
—
—
0
0
28
223
1.23
0.42
1.8
1.5
1.55
2.59
u/ml
0.58
19
162
5
31
1.57
0.42
1.0
1.2
207.00
235.95
iu/ml
—
5
31
208
1908
1.09
0.42
11.8
5.2
33.09
25.71
u/l
1.36
195
1834
17
127
1.30
0.42
6.0
6.0
3.75
2.11
ug/l
1.37
17
127
15
110
1.33
0.41
2.7
2.5
0.00
0.00
estimate
—
8
55
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
5
32
1.52
0.41
1.4
1.0
—
—
—
0
0
5
32
1.52
0.41
1.0
1.1
—
—
—
0
0
10
68
1.43
0.41
1.2
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
1.21
—
0
16
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
62
672
0.88
0.40
1.7
1.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
112.22
—
0
17
195
1787
1.09
0.40
9.3
9.0
—
—
—
0
0
122
1094
1.10
0.40
6.1
4.3
—
—
—
0
0
7
99
0.68
0.40
1.0
1.0
1.50
1.47
g/l
—
7
99
39
324
1.18
0.40
2.8
1.8
2.42
2.42
mmol/l
0.09
34
270
0
18
0.00
0.39
0.0
20.1
—
—
—
0
0
62
670
0.88
0.39
1.6
1.8
—
—
—
0
0
407
4022
0.91
0.38
14.6
11.6
54.11
56.15
umol/l
1.23
402
3948
56
481
1.14
0.38
24.2
18.2
107.32
105.79
mmol/l
2.29
56
481
8
109
0.71
0.37
1.0
1.9
23.10
6.15
ug/l
—
8
102
50
427
1.15
0.37
2.9
2.5
4.87
6.50
iu/l
0.95
31
255
105
939
1.10
0.37
3.0
2.6
—
—
—
0
0
385
3811
0.92
0.37
24.7
16.1
139.34
139.43
mmol/l
0.38
374
3717
159
1451
1.09
0.36
5.4
4.9
0.84
0.20
e6/l
0.71
112
1048
35
291
1.18
0.36
33.8
21.9
5.21
5.39
kpa
0.66
35
283
35
291
1.18
0.36
33.8
21.9
15.89
15.80
kpa
0.03
35
283
114
1025
1.10
0.36
3.3
3.6
58.23
85.41
ug/g
1.36
93
821
20
157
1.24
0.35
5.8
10.6
24.71
23.85
mmol/l
0.56
20
147
13
96
1.32
0.35
2.7
3.6
3.52
3.21
e9/l
0.25
13
96
6
43
1.35
0.34
1.2
1.1
—
96.50
—
0
8
13
161
0.78
0.34
1.3
1.3
—
—
—
0
0
197
1818
1.08
0.34
6.8
6.2
70.74
50.57
e6/l
0.23
132
1193
35
293
1.17
0.34
33.8
21.8
7.43
7.37
ph
—
10
80
10
71
1.37
0.33
1.2
1.1
—
—
—
0
0
103
927
1.09
0.32
5.8
6.3
1.09
1.18
inr
0.83
81
767
118
1216
0.92
0.31
16.6
11.5
5.00
5.18
kpa
0.63
118
1187
28
315
0.85
0.31
2.0
2.2
—
—
—
0
0
26
214
1.18
0.31
1.7
1.6
14.80
5.62
u/ml
0.29
19
151
7
97
0.69
0.31
5.4
5.1
15.71
20.10
index
—
7
88
14
169
0.80
0.30
1.0
1.1
—
—
—
0
0
40
343
1.14
0.29
1.7
1.5
—
—
—
0
0
25
282
0.85
0.29
1.2
1.1
—
—
—
0
0
22
180
1.19
0.28
6.5
5.2
—
—
—
0
0
8
62
1.25
0.27
3.5
5.5
28.15
25.49
ug/l
—
8
62
8
64
1.21
0.27
2.8
3.1
—
—
—
0
0
129
1183
1.07
0.26
2.1
2.3
—
—
—
0
0
58
514
1.10
0.26
1.2
1.2
1.11
1.16
u/ml
0.03
41
372
14
165
0.82
0.26
4.4
4.1
3.37
9.23
index
—
8
112
60
631
0.91
0.26
1.7
1.8
—
—
—
0
0
20
227
0.85
0.25
1.2
1.2
—
—
—
0
0
135
1242
1.07
0.25
19.1
10.9
7.40
7.41
ph
0.76
113
994
43
375
1.12
0.25
2.2
2.6
23.03
28.28
u/l
1.51
34
295
16
128
1.22
0.25
5.4
4.5
—
—
—
0
0
14
164
0.82
0.24
1.0
1.4
—
—
—
0
0
9
74
1.18
0.24
1.0
1.1
—
—
—
0
0
123
1252
0.94
0.24
16.5
11.8
5.79
5.79
kpa
0.02
123
1221
387
3806
0.94
0.23
24.4
16.1
3.95
3.94
mmol/l
0.30
376
3687
31
266
1.14
0.23
1.0
1.0
2.86
3.24
kpa
1.08
25
220
131
1208
1.07
0.23
2.8
3.1
0.00
0.00
estimate
0.50
32
254
123
1250
0.94
0.23
17.2
11.9
7.38
7.37
ph
2.17
88
857
7
88
0.77
0.22
5.4
5.2
1.29
0.65
index
—
7
88
328
3238
0.95
0.22
4.5
3.6
14.33
14.48
pmol/l
0.56
298
2906
362
3564
0.95
0.22
4.8
4.1
2.07
2.04
mu/l
0.15
342
3390
68
705
0.92
0.22
1.6
1.4
113.33
155.42
titre
—
6
26
217
2035
1.05
0.22
3.7
2.9
1.09
1.06
mmol/l
0.30
209
1939
104
954
1.07
0.22
2.4
2.9
1.02
1.02
kg/l
0.61
58
583
150
1393
1.06
0.21
5.4
4.1
—
—
estimate
—
0
0
166
1667
0.95
0.21
2.6
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
82.25
—
0
11
104
955
1.07
0.21
1.4
1.3
—
—
—
0
0
5
41
1.18
0.21
1.0
1.1
314.80
283.63
mg/l
—
5
41
52
464
1.09
0.21
2.8
2.0
—
—
—
0
0
81
832
0.93
0.21
1.8
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
93.67
—
0
12
24
204
1.14
0.21
1.3
1.2
—
—
—
0
0
51
455
1.09
0.21
2.9
2.5
4.43
5.22
u/l
0.38
29
252
123
1245
0.94
0.21
16.1
11.8
0.89
0.94
mmol/l
0.07
109
1004
6
46
1.26
0.20
6.2
5.9
190.17
134.26
umol/l
—
6
23
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
31
270
1.12
0.19
1.0
1.0
-1.88
-2.43
mmol/l
—
8
68
31
270
1.12
0.19
1.0
1.0
7.59
7.31
kpa
0.42
25
223
31
270
1.12
0.19
1.0
1.0
—
—
—
0
0
58
523
1.08
0.19
1.2
1.2
4.54
6.30
u/ml
0.61
43
399
13
105
1.20
0.19
6.3
5.6
—
—
—
0
0
10
79
1.23
0.17
2.4
2.3
—
—
—
0
0
61
554
1.07
0.17
1.3
1.3
3.08
2.97
u/ml
0.03
47
402
118
1097
1.05
0.17
18.8
10.6
—
—
—
0
0
39
348
1.09
0.16
2.5
2.0
—
—
—
0
0
8
66
1.18
0.16
8.0
2.3
28.44
23.63
mg/l
—
8
42
29
255
1.11
0.16
2.4
3.0
5.16
5.16
pmol/l
0.00
29
238
104
966
1.05
0.15
2.2
2.1
1.18
1.19
mmol/l
0.06
99
906
14
156
0.86
0.15
1.6
1.3
—
—
—
0
0
41
426
0.93
0.15
10.5
9.7
1324.12
1343.51
ng/l
0.01
33
367
53
544
0.94
0.14
1.6
1.8
—
—
—
0
0
96
892
1.05
0.14
8.6
5.6
—
—
—
0
0
225
2131
1.04
0.14
26.4
17.4
1.23
1.23
mmol/l
0.36
217
2047
240
2368
0.96
0.14
5.0
3.9
50.21
48.10
ug/l
0.11
231
2272
8
95
0.81
0.14
2.1
1.5
—
—
—
0
0
13
109
1.16
0.13
2.2
1.8
3.12
3.56
iu/l
—
5
46
22
193
1.11
0.13
31.6
20.4
64.86
70.36
%
0.55
22
193
498
4795
1.08
0.12
26.8
19.2
6.95
6.98
e9/l
0.07
479
4540
14
119
1.14
0.12
2.5
1.7
0.35
0.22
nmol/l
—
9
90
497
4786
1.08
0.12
26.9
19.3
276.57
274.20
e9/l
0.30
479
4543
42
428
0.95
0.10
1.4
1.3
176.84
163.44
u/ml
0.08
17
107
497
4789
1.07
0.09
26.8
19.2
4.64
4.62
e12/l
0.24
477
4534
34
310
1.07
0.09
1.1
1.1
1.25
0.88
u/ml
0.12
23
162
46
466
0.95
0.09
1.5
2.2
—
—
—
0
0
497
4790
1.06
0.09
30.3
21.2
39.69
40.12
%
0.25
492
4729
77
721
1.04
0.09
1.3
1.3
—
7.92
—
0
6
5
58
0.83
0.08
6.6
2.6
0.79
1.58
ug/l
—
5
53
24
217
1.07
0.08
1.3
1.2
3.03
2.92
mmol/l
0.19
12
127
233
2284
0.98
0.08
3.8
3.2
4.16
4.23
mmol/l
0.66
223
2190
79
743
1.03
0.07
1.6
2.0
—
—
—
0
0
47
437
1.04
0.07
1.7
2.0
—
—
—
0
0
16
168
0.92
0.07
2.6
2.3
1.21
0.42
nmol/l
0.72
16
152
23
237
0.94
0.07
2.4
2.4
51.48
52.95
%
0.21
23
237
27
247
1.06
0.07
2.0
2.1
0.00
0.00
estimate
-0.00
11
68
8
91
0.85
0.06
1.4
1.6
—
—
—
0
0
54
505
1.04
0.06
1.2
1.2
8.51
3.41
u/ml
1.10
43
375
92
870
1.03
0.06
5.0
4.3
7.38
7.38
ph
0.09
54
598
67
630
1.03
0.06
1.7
1.7
—
—
—
0
0
9
100
0.87
0.06
1.2
1.1
0.86
0.82
g/l
—
9
100
9
101
0.86
0.06
1.3
1.4
13.19
13.77
u/ml
—
9
92
29
267
1.05
0.06
24.7
16.8
0.53
0.61
%
0.92
29
267
190
1861
0.98
0.06
5.1
4.2
69.20
67.19
nmol/l
0.52
178
1777
12
127
0.91
0.06
8.2
5.4
7.38
7.33
ph
—
7
99
32
296
1.05
0.06
27.0
17.7
123.44
126.49
g/l
0.32
32
289
20
182
1.07
0.05
6.2
3.8
239.93
191.31
e6/l
0.38
14
117
61
575
1.03
0.05
2.3
1.6
251.43
411.28
titre
—
7
78
32
322
0.96
0.05
1.7
1.4
—
—
—
0
0
117
1149
0.98
0.04
20.0
14.1
—
—
—
0
0
21
214
0.95
0.04
1.5
1.3
—
—
—
0
0
35
327
1.04
0.04
1.2
1.2
6.61
11.76
u/ml
0.82
25
215
441
4253
1.02
0.03
19.1
12.9
23.16
24.09
mg/l
0.21
315
3030
21
213
0.95
0.03
1.6
1.3
—
—
—
0
0
16
164
0.94
0.03
6.9
5.6
—
—
—
0
0
20
203
0.95
0.03
1.3
1.3
—
—
—
0
0
20
201
0.96
0.02
1.1
1.3
232.06
206.43
miu/ml
—
9
86
20
201
0.96
0.02
1.9
1.6
0.16
0.19
mg/l
—
8
76
15
138
1.05
0.02
1.3
1.3
—
—
—
0
0
232
2237
1.01
0.01
3.6
3.1
2.52
2.54
mmol/l
0.20
223
2128
230
2231
1.00
0.00
23.4
15.1
1.23
1.23
mmol/l
0.58
214
2092
19
179
1.03
0.00
6.1
3.8
966.38
536.41
e6/l
1.67
13
115
36
347
1.00
0.00
1.2
1.2
6.96
7.58
u/ml
0.06
27
234
20
192
1.01
0.00
7.0
4.9
2.50
7.91
e6/l
0.70
14
129
20
192
1.01
0.00
7.0
4.9
502.93
937.03
e6/l
0.26
14
132
11
109
0.98
0.00
1.7
1.4
—
—
—
0
0
10
96
1.01
0.00
1.5
1.5
—
—
—
0
0
13
128
0.98
0.00
1.0
1.2
—
—
—
0
0
15
145
1.00
0.00
45.2
25.0
9.82
11.60
%
1.12
15
145
230
2229
1.00
0.00
3.6
3.1
1.35
1.39
mmol/l
1.04
220
2122
24
237
0.98
0.00
1.6
1.8
6.11
6.32
ph
0.52
18
153
19
186
0.99
0.00
6.5
3.9
0.65
0.38
e9/l
0.64
12
109
49
479
0.99
0.00
2.2
2.5
—
—
—
0
0
19
184
1.00
0.00
6.6
3.8
2278.14
1488.07
e6/l
1.05
14
121
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
9
90
0.97
0.00
1.8
1.2
—
0.20
—
0
6
0
5
0.00
0.00
0.0
1.0
—
76.80
—
0
5
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
740.60
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
97.00
—
0
5
7
71
0.95
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
15.0
—
13.29
—
0
9
5
49
0.99
-0.00
1.2
1.2
102.40
121.94
pmol/l
—
5
49
8
77
1.01
-0.00
1.3
1.1
35.94
32.51
iu/ml
—
8
77
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
65
0.89
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
9
86
1.01
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1492.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
180.17
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
58
1.00
-0.00
22.0
3.9
4.57
4.97
kpa
—
6
58
0
6
0.00
-0.00
0.0
22.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
89
0.98
-0.00
1.1
1.5
—
290.00
—
0
5
6
64
0.91
-0.00
1.0
3.0
16.67
19.28
u/ml
—
6
53
5
55
0.88
-0.00
1.4
1.2
—
—
—
0
0
5
53
0.91
-0.00
1.0
1.7
11.56
8.08
umol/l
—
5
53
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_NEONTAL_JAUND_OTH_UNSP_CAUSES and mortality.

Females

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 0.886 [0.66, 1.18] 0.414
Birth year 0.992 [0.98, 1.0] 0.071

During the follow-up period (1.1.1998 — 31.12.2019), 56 out of 21667 females with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Males

Parameter HR [95% CI] p-value
P16_NEONTAL_JAUND_OTH_UNSP_CAUSES 1.62 [1.3, 2.02] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 30217 males with P16_NEONTAL_JAUND_OTH_UNSP_CAUSES died.

Mortality risk

Mortality risk for people of age

years, who have P16_NEONTAL_JAUND_OTH_UNSP_CAUSES.

N-year risk Females Males
1 0.074% 0.285%
5 0.496% 1.797%
10 1.153% 4.374%
15 2.246% 8.121%
20 4.072% 13.464%

Relationships between endpoints

Index endpoint: P16_NEONTAL_JAUND_OTH_UNSP_CAUSES – Neonatal jaundice from other and unspecified causes

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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