Oesophagitis, drug-induced

K11_OESITIS_ADVERSE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ATC codes for adverse effects of Drugs — ANY Hospital discharge: ICD-10 — K20 1 out of 7 registries used, show all original rules.	89
4. Check minimum number of events None	89
5. Include endpoints None	89
6. Filter based on genotype QC (FinnGen only)	79

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5
Parent code in ICD-10: K00-K14
Name in latin: Oesophagitis

NAME	K11_OESITIS_ADVERSE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC	ANY
HD_ICD_10	K20
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Oesophagitis, drug-induced based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	79	41	38
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	49.55	48.24	50.96

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
82: Matched controls
820

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K20

ICD-10 Finland

Oesophagitis

+∞

110.4

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

10.3

23.0

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

8.0

19.3

181

A02BC01

ATC

omeprazole; systemic

4.8

11.4

166

A02BA02

ATC

ranitidine; systemic

4.3

9.0

106

UJD02

NOMESCO Finland

Gastroscopy

8.6

8.0

K44.9

ICD-10 Finland

Diaphragmatic hernia without obstruction or gangrene

5.3

7.9

A03FA02

ATC

cisapride; oral, rectal

5.3

7.9

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

3.6

7.6

200

JBC01

NOMESCO Finland

Laparoscopic gastro-oesophageal antireflux operation

24.9

6.8

A02BC03

ATC

lansoprazole; oral

3.2

6.3

173

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

102

3.27

5.38

1.9

1.2

—

(1002224) Polysomnography panel

3.31

2.45

1.3

1.1

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

6.56

2.40

1.6

1.8

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

6.56

2.40

1.6

1.8

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

323

1.97

2.31

3.8

3.3

142.50

131.47

ug/l

0.11

302

(4034850) Laboratory test

3.43

2.16

3.4

8.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.13

2.15

1.2

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

3.13

2.15

1.0

1.1

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

345

1.85

1.95

2.7

2.2

99.07

97.62

pmol/l

0.06

179

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.31

1.89

2.1

1.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.23

1.84

1.9

1.3

—

(3018418) pH of Serum or Plasma

238

1.82

1.83

6.0

4.2

7.40

0.08

160

(3013650) Neutrophils [#/volume] in Blood by Automated count

432

1.83

1.76

13.7

9.8

3.90

4.24

e9/l

0.57

379

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

3.32

1.69

1.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.39

1.65

1.5

1.4

—

(3019230) Fractional oxyhemoglobin in Venous blood

3.73

1.64

5.0

3.8

69.80

61.14

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.02

1.62

3.1

1.6

—

(3026493) Urate [Moles/volume] in Serum or Plasma

210

1.77

1.61

2.5

2.7

339.92

349.83

umol/l

0.15

183

(3014765) Yersinia sp identified in Stool by Organism specific culture

3.48

1.54

1.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

3.48

1.54

1.0

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

3.48

1.54

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

3.48

1.54

1.2

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.34

1.46

3.5

4.6

24.36

24.27

mmol/l

—

(3008898) HLA-B27 [Presence]

2.86

1.46

1.0

1.1

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.54

1.42

1.9

1.1

0.33

0.24

g/l

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.90

1.40

1.2

1.6

—

(3009508) Creatinine [Moles/volume] in Urine

263

1.66

1.39

3.5

3.3

6.38

7.61

mmol/l

0.96

225

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

378

1.65

1.38

10.9

7.2

1.21

mmol/l

0.01

323

(3012516) Albumin [Mass/volume] in Urine

256

1.64

1.34

3.7

3.4

28.59

73.21

mg/l

1.31

169

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.61

1.33

1.3

1.0

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.22

1.22

1.4

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.90

1.22

2.4

2.7

4.00

10.44

umol/l

0.86

(42870588) Differential panel, method unspecified - Blood

253

1.59

1.18

10.0

6.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.59

1.17

1.4

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.45

1.15

1.9

1.2

1.52

1.17

g/l

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

139

1.69

1.15

1.7

1.4

31.22

10.65

u/ml

—

(3001604) Monocytes [#/volume] in Blood

389

1.56

1.14

8.2

6.2

0.56

0.58

e9/l

0.33

328

(3006315) Basophils [#/volume] in Blood

390

1.56

1.12

8.2

6.2

0.04

e9/l

0.01

328

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.96

1.09

16.4

8.6

1.15

1.21

mmol/l

0.15

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.22

1.08

2.9

2.2

—

(3045414) Leukocytes [Presence] in Urine

1.84

1.06

2.4

1.9

0.00

estimate

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.84

1.06

3.4

1.6

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.35

1.05

1.4

2.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

269

1.53

1.03

4.0

4.1

5.95

12.91

mg/mmol

0.91

172

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

126

1.66

1.03

1.8

1.9

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.94

1.02

17.8

9.0

24.19

24.31

mmol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

161

1.60

1.01

4.8

2.3

—

(3013115) Eosinophils [#/volume] in Blood

396

1.51

1.01

8.9

6.4

0.17

0.19

e9/l

0.37

340

(3000492) Spirometry study

1.84

0.99

1.4

1.6

—

(3000494) Fungus identified in Specimen by Culture

1.76

0.98

1.6

1.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.23

0.93

1.2

1.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

113

1.64

0.91

3.2

1.9

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.90

0.89

3.8

3.3

0.50

0.60

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.08

0.89

1.3

1.2

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.82

0.85

3.7

3.3

2.20

1.26

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

107

1.62

0.84

12.1

6.4

102.81

103.92

mmol/l

0.30

107

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

151

1.53

0.82

4.1

3.7

97.69

188.45

ng/l

0.40

118

(3025941) Bacteria identified in Stool by Culture

1.88

0.81

1.2

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.80

0.0

2.9

—

3.94

—

(3000991) Gas panel - Venous blood

1.74

0.80

16.5

9.6

—

(3015736) pH of Urine

330

1.41

0.78

2.9

3.4

6.08

6.19

0.20

178

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

101

1.59

0.77

2.0

1.7

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.15

0.76

1.0

1.3

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.15

0.76

3.4

1.5

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

293

1.41

0.75

1.9

1.46

1.38

mmol/l

0.23

239

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.06

0.74

1.4

2.1

—

(40761536) Microorganisms panel - Urine sediment

1.69

0.72

4.7

3.7

—

(3049717) Cytology report of Urine Cyto stain

1.98

0.72

2.4

3.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

156

1.47

0.70

3.9

3.3

0.55

0.79

ug/l

1.58

109

(40758558) Short blood count panel - Blood

222

1.40

0.66

13.3

6.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.70

0.64

2.0

1.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.59

0.64

2.4

1.9

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

418

1.36

0.63

6.0

6.3

9.96

11.41

umol/l

0.96

391

(3021589) Normoblasts [#/volume] in Blood

339

1.35

0.63

17.1

13.7

0.00

e9/l

0.49

272

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.62

1.0

1.2

0.00

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

320

1.35

0.62

3.6

4.3

18.41

28.76

ng/l

1.11

236

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.59

0.60

1.9

2.4

415.91

378.91

nmol/l

0.31

(3004588) Protein electrophoresis panel - Serum or Plasma

1.61

0.58

1.1

1.2

—

(4035726) Immunohistochemistry procedure

1.61

0.58

1.5

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.67

0.57

1.0

1.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.58

0.56

6.7

5.5

35.50

33.05

—

(36660697) Celiac disease serology panel - Serum

1.51

0.55

1.1

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

238

1.34

0.55

4.2

3.9

0.08

0.00

estimate

0.47

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.58

0.54

1.3

2.0

1.91

1.66

g/l

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

156

1.37

0.51

1.8

1.3

13.09

41.56

iu/ml

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.61

0.50

1.6

1.9

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.50

0.48

1.9

1.2

84.11

698.83

u/ml

—

(3002582) Erythrocytes [#/volume] in Urine

271

1.30

0.48

3.5

3.4

39.58

292.67

e6/l

0.51

199

(3022145) Colonoscopy Study observation

1.44

0.47

1.2

1.3

—

(3042936) Bacteria identified in Isolate by Culture

113

1.40

0.47

2.1

2.2

—

(3030467) Casts [#/volume] in Urine by Automated count

234

1.30

0.46

3.4

3.2

0.03

0.44

e6/l

4.21

165

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.42

0.45

2.2

1.7

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.1

—

6.67

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.41

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.41

0.0

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

125

1.35

0.41

3.2

3.3

2.27

2.66

e6/l

—

(3044640) Blood type and Crossmatch panel - Blood

228

1.27

0.41

4.4

2.3

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.40

0.0

3.9

—

29.78

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

172

1.30

0.39

1.2

3.82

1.63

u/ml

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.67

0.35

4.7

7.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

419

1.22

0.34

3.7

3.9

0.00

estimate

-0.00

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

204

1.25

0.34

5.1

4.7

21.07

20.34

0.11

109

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.70

0.33

1.3

1.4

—

(3019150) Specific gravity of Urine by Refractometry

167

1.26

0.32

2.8

3.8

1.02

kg/l

0.19

107

(3007164) IgA [Mass/volume] in Serum or Plasma

158

1.26

0.32

1.6

1.3

1.91

2.76

g/l

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.35

0.32

2.4

3.0

137.00

247.41

ng/l

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.35

0.32

21.1

9.0

0.84

1.24

—

(40761511) CBC panel - Blood by Automated count

699

0.77

0.31

18.6

16.2

—

(3009261) Glucose [Presence] in Urine by Test strip

422

1.21

0.31

3.7

3.9

0.00

estimate

-0.00

(3035350) Ketones [Presence] in Urine by Test strip

422

1.21

0.31

3.7

3.8

0.00

estimate

-0.00

101

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

141

1.26

0.29

3.1

3.0

0.20

1.49

e6/l

—

(3026008) Bacteria identified in Urine by Culture

237

1.21

0.28

3.7

3.1

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.34

0.27

1.2

1.6

66.48

67.09

g/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

230

0.83

0.25

3.9

3.7

0.11

0.00

estimate

—

(40768443) Skin Pathology biopsy report

1.37

0.24

1.4

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.30

0.23

7.2

4.2

—

(1761868) Lipid panel - Serum or Plasma

258

0.85

0.22

3.2

3.5

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

709

1.27

0.21

26.7

20.9

139.58

139.56

mmol/l

0.01

698

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3012441) Differential panel - Pleural fluid

0.00

0.21

0.0

2.0

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

1.44

—

(3045788) Cell count panel - Pleural fluid

0.00

0.21

0.0

1.6

—

(4146454) Self-monitoring of blood glucose

0.00

0.21

0.0

3.6

—

(4268621) Lupus anticoagulant assay

0.00

0.21

0.0

1.7

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.1

—

(3003694) ABO and Rh group [Type] in Blood

194

1.18

0.21

1.7

1.4

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

4.00

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.21

0.0

1.3

—

251.75

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

1.20

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

2.1

—

15.73

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.7

—

106.33

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.21

0.0

1.6

—

6.48

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.21

0.0

1.9

—

33.15

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

3.3

—

0.75

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.17

0.19

25.3

9.1

0.42

0.62

—

(3023368) Bacteria identified in Blood by Culture

225

1.16

0.19

6.4

3.9

—

(40761535) Cells panel - Urine sediment

1.23

0.19

2.7

3.2

—

(3032080) INR in Blood by Coagulation assay

384

1.14

0.18

22.2

13.8

1.18

1.24

inr

0.36

311

(3005719) IgG [Mass/volume] in Serum or Plasma

1.14

0.18

2.1

1.8

9.40

10.33

g/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.14

0.18

1.3

1.4

—

(3000963) Hemoglobin [Mass/volume] in Blood

739

0.89

0.15

36.5

26.9

135.58

134.36

g/l

0.31

731

(3035941) MCH [Entitic mass]

739

0.89

0.15

36.0

26.5

30.47

30.43

0.07

731

(3009542) Hematocrit [Volume Fraction] of Blood by calculation

739

0.89

0.15

38.4

27.1

39.60

40.10

0.23

731

(3018095) Leukocytes [#/volume] in Urine

307

1.13

0.15

4.1

77.97

139.57

e6/l

0.35

208

(3024731) MCV [Entitic mean volume] in Red Blood Cells

738

0.90

0.15

36.1

26.6

91.61

91.50

0.08

730

(40760892) CBC W Ordered Manual Differential panel - Blood

171

1.14

0.14

3.2

4.5

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

711

1.24

0.14

27.5

21.0

4.03

3.99

mmol/l

0.53

698

(3027945) Reticulocytes/Erythrocytes in Blood

1.18

0.12

3.5

2.5

1.59

1.84

0.42

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

266

0.91

0.09

6.6

5.8

2.96

2.02

ug/l

0.68

235

(3028026) IgM [Mass/volume] in Serum or Plasma

1.14

0.09

2.3

1.6

0.46

1.13

g/l

—

(3021440) Promyelocytes/Leukocytes in Blood

1.03

0.08

3.6

4.4

—

0.22

—

(3025159) Blasts/Leukocytes in Blood

1.09

0.08

2.9

4.7

—

0.10

—

(40768804) Tissue Pathology biopsy report

297

1.07

0.06

2.1

2.2

—

(3014051) Protein [Presence] in Urine by Test strip

222

0.93

0.06

2.4

3.1

—

0.40

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

308

1.06

0.05

3.9

4.0

0.30

0.00

estimate

—

(3031040) Bacteria [#/volume] in Urine by Automated count

491

0.95

0.04

6.7

4.6

—

72.22

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

379

1.06

0.04

3.0

2.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

338

0.96

0.02

5.1

2.6

—

estimate

—

(3013512) EKG study

277

0.96

0.01

3.6

4.2

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

723

0.97

0.00

15.9

13.1

30.11

25.31

u/l

0.58

704

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

676

1.03

0.00

22.6

18.1

77.70

77.12

ml/min/173m2

0.08

630

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

686

1.04

0.00

23.5

17.4

21.09

23.19

mg/l

0.31

576

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.0

—

136.38

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(3002179) Metamyelocytes/Leukocytes in Blood

1.02

0.00

3.6

4.1

—

0.95

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.96

0.00

1.2

2.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.8

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.87

-0.00

1.2

2.2

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(3036603) Volume of Urine

0.00

-0.00

0.0

3.4

—

1444.00

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

0.61

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3020491) Glucose [Moles/volume] in Blood

0.00

-0.00

0.0

2.0

—

7.46

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.8

—

3.38

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.0

—

0.71

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

4.54

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3035880) pH of Pleural fluid

0.00

-0.00

0.0

1.2

—

7.34

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.0

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

112.29

—

(3019225) pH of Specimen

0.86

-0.00

10.2

3.6

7.39

7.34

—

(3002256) Pathology report gross observation

0.98

-0.00

1.8

1.2

—

(3003396) Base excess in Arterial blood by calculation

1.00

-0.00

18.0

7.0

-0.43

0.69

mmol/l

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.7

—

(3017181) Myelocytes/Leukocytes in Blood

0.96

-0.00

3.6

4.2

—

0.83

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

3.7

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

12.22

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

9.82

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

1.7

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

65.50

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

70.00

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.7

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

11.6

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

728

1.03

-0.00

27.5

23.5

92.67

79.98

umol/l

0.54

719

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

67.00

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

↥

Index endpoint: K11_OESITIS_ADVERSE – Oesophagitis, drug-induced

GWS hits: 1

This endpoint is excluded (not available in FinRegistry).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Oesophagitis, drug-induced

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Oesophagitis, drug-induced (K11_OESITIS_ADVERSE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints