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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of oropharyng

C3_OROPHARYNG

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C10
  • Cause of death: ICD-9 146
  • Cause of death: ICD-8 146
  • Cause of death: excluded ICD-9 1460A
  • Cancer registry: Topography ICD-O-3 C10
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

67

4. Check minimum number of events

None

67

5. Include endpoints

None

67

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 61 20 41
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 67.89 67.83 67.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
64
Matched controls
640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
61.8
49
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
+∞
46.7
39
*
A03FA01
ATC
metoclopramide; systemic, rectal
27.2
42.0
42
42
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
425.9
41.0
37
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
37.1
32
*
N02AA05
ATC
oxycodone; systemic
20.2
34.6
41
52
C10.3
ICD-10 Finland
Malignant neoplasm: Posterior wall of oropharynx
+∞
23.3
21
*
8070/3-C10.9
ICD-O-3
Squamous cell carcinoma, NOS, of oropharynx, NOS
+∞
22.2
20
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
22.2
20
*
R4190
NOMESCO Finland
Nutritional therapy
69.9
20.9
23
5
H02AB02
ATC
dexamethasone; systemic
142.2
19.8
20
*
WZC00
NOMESCO Finland
Treatment plan or consultation
9.5
18.7
41
101
A04AA01
ATC
ondansetron; systemic, rectal
88.1
17.9
19
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
+∞
17.5
16
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
17.5
16
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
16.3
15
*
UJC01
NOMESCO Finland
Scopy of lower throat
43.9
15.9
19
6
XX3DW
NOMESCO Finland
Time consuming IT work
25.0
15.7
22
13
GBB00
NOMESCO Finland
Tracheostomy
104.5
15.4
16
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
15.2
14
*
C10.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oropharynx
+∞
15.2
14
*
C10.0
ICD-10 Finland
Malignant neoplasm: Vallecula
+∞
14.1
13
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
175.8
14.0
14
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
175.8
14.0
14
*
A06AD11
ATC
lactulose; oral
8.5
13.6
22
37
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
12.9
12
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
12.9
12
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
11.8
11
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
11.8
11
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
18.7
11.3
17
12
Z51.5
ICD-10 Finland
Palliative care
16.2
11.2
18
15
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
12.7
11.1
20
22
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.7
10
*
SAA03
NOMESCO Finland
Extended examination of mouth
5.6
10.7
39
140
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
5.7
10.4
43
170
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.5
10.2
21
45
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
116.5
9.7
10
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
11.4
9.6
18
21
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
9.6
9
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
9.6
9
*
C10.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of oropharynx
+∞
9.6
9
*
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
9.6
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
19.4
9.6
14
9
WW500
NOMESCO Finland
Blood transfusion
32.6
8.8
11
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
32.6
8.8
11
*
WX002
NOMESCO Finland
Sedation and analgesia
5.1
8.8
25
71
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
8.5
8
*
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
+∞
8.5
8
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
8.5
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.5
8
*
C10.9
ICD-10 Finland
Malignant neoplasm: Oropharynx, unspecified
+∞
8.5
8
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
8.2
26
80
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
21.7
7.9
11
6
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
90.1
7.6
8
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.9
7.6
16
23
WX402
NOMESCO Finland
General anaesthesia
4.6
7.5
24
74
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.4
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.4
7.4
26
86
A02BC05
ATC
esomeprazole; systemic
4.2
7.3
40
182
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.2
7.2
16
25
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
25.7
6.9
9
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
7.5
6.9
16
27
EBA10
NOMESCO Finland
Operative extraction of tooth
9.1
6.9
14
19
GD1AD
NOMESCO Finland
Thorax CT examination
7.8
6.7
15
24
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
77.2
6.6
7
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
77.2
6.6
7
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
6.7
6.4
16
30
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
+∞
6.3
6
*
8070/3-C10.3
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of oropharynx
+∞
6.3
6
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
K12.10
ICD-10 Finland
Stomatitis NOS
+∞
6.3
6
*
Z3226
NOMESCO Finland
Physiotherapist
4.2
6.3
21
66
TPH07
NOMESCO Finland
Cathetrisation of artery
4.9
6.1
16
41
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.9
6.1
44
232
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
12.9
6.0
10
9
R4110
NOMESCO Finland
Physiotherapy
3.7
6.0
28
111

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
13
41.90
24.24
1.4
1.6
—
—
—
0
0
45
169
6.60
12.03
2.6
1.6
—
—
—
0
0
35
146
4.08
7.21
4.7
3.9
—
—
—
0
0
36
160
3.86
6.63
8.5
2.1
2.38
2.35
mmol/l
0.68
36
134
24
83
4.03
6.31
2.3
1.9
—
—
—
0
0
44
233
3.84
6.05
3.2
2.3
—
—
estimate
—
0
0
34
166
3.24
5.07
3.0
2.0
—
—
—
0
0
18
62
3.65
4.62
1.8
1.8
—
—
—
0
0
7
7
11.02
4.11
1.3
1.3
21.86
24.51
ng/l
—
7
7
47
300
3.13
4.06
16.2
6.3
4.83
4.29
e9/l
0.66
42
260
14
46
3.62
3.80
1.2
1.1
—
—
—
0
0
43
284
2.57
3.10
11.7
13.8
1.22
1.28
inr
0.26
37
229
28
153
2.48
3.04
12.6
5.0
—
—
—
0
0
17
73
2.81
2.96
2.0
1.9
—
—
—
0
0
31
184
2.33
2.74
6.2
4.9
—
—
—
0
0
16
77
2.44
2.20
8.9
7.6
102.25
104.42
mmol/l
0.46
16
77
10
37
3.01
2.18
12.7
12.4
93.90
93.74
%
—
10
37
53
421
2.51
2.07
13.8
5.7
74.74
76.15
u/l
0.14
53
398
0
51
0.00
1.99
0.0
2.2
—
5.87
—
0
39
17
89
2.24
1.93
5.7
1.7
2.59
2.44
mmol/l
2.74
17
70
25
154
2.02
1.88
4.1
4.4
7.40
7.40
ph
0.03
14
109
38
274
1.95
1.80
10.8
7.3
1.21
1.20
mmol/l
0.19
38
241
10
40
2.77
1.76
12.7
11.5
0.94
0.76
%
—
10
40
10
40
2.77
1.76
12.7
11.5
1.36
1.46
%
—
10
40
45
346
2.01
1.74
8.3
5.0
6.94
6.90
mmol/l
0.05
45
329
6
20
3.20
1.62
1.5
1.1
—
—
—
0
0
14
73
2.17
1.59
11.5
8.8
7.41
7.43
ph
—
9
43
39
295
1.82
1.49
7.1
5.1
0.21
0.19
e9/l
0.19
30
253
9
40
2.45
1.47
5.0
4.9
—
—
—
0
0
38
286
1.81
1.46
7.2
5.1
0.63
0.58
e9/l
0.74
30
243
38
289
1.78
1.39
7.2
5.1
0.04
0.04
e9/l
0.04
30
244
38
289
1.78
1.39
7.2
5.2
1.65
1.77
e9/l
0.20
29
254
6
25
2.54
1.27
3.8
3.9
37.08
36.90
°c
—
6
25
10
50
2.19
1.24
12.8
11.0
—
—
—
0
0
22
149
1.73
1.16
1.3
1.3
—
—
—
0
0
7
130
0.48
1.02
3.3
2.0
1.89
3.78
e6/l
—
7
113
14
210
0.57
1.01
2.9
3.7
—
—
—
0
0
6
33
1.90
0.81
16.8
11.9
28.60
24.59
mmol/l
—
6
33
5
25
2.08
0.74
1.0
1.2
—
—
—
0
0
13
184
0.63
0.70
1.8
2.9
0.53
0.77
ug/l
—
8
123
8
49
1.72
0.65
2.3
3.6
7.42
7.42
ph
—
8
38
5
29
1.78
0.65
1.0
1.6
—
—
—
0
0
0
20
0.00
0.61
0.0
5.8
—
—
—
0
0
0
19
0.00
0.61
0.0
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
3.0
—
1.77
—
0
13
9
59
1.61
0.58
1.2
1.4
—
—
—
0
0
6
38
1.64
0.56
1.0
1.3
—
—
—
0
0
19
239
0.71
0.55
4.5
3.7
—
—
—
0
0
20
156
1.41
0.54
3.1
2.5
0.33
0.32
e6/l
0.02
12
114
7
47
1.55
0.49
5.6
2.3
64.10
67.09
g/l
—
7
41
7
49
1.48
0.48
1.1
1.3
—
—
—
0
0
5
33
1.56
0.42
3.0
4.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
6
44
1.40
0.35
1.0
1.7
—
—
—
0
0
13
102
1.34
0.33
1.7
1.8
31.47
29.37
s
0.50
13
97
12
95
1.32
0.29
1.4
1.6
1068.71
1239.84
nmol/l
—
7
81
28
252
1.20
0.23
14.0
10.3
0.02
0.00
e9/l
0.48
22
209
17
146
1.22
0.22
2.6
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
60.00
—
0
11
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
4.20
—
0
13
0
13
0.00
0.21
0.0
3.9
—
12.95
—
0
13
0
14
0.00
0.20
0.0
4.1
—
63.44
—
0
14
0
14
0.00
0.20
0.0
1.2
—
0.23
—
0
14
0
14
0.00
0.20
0.0
1.3
—
1.02
—
0
14
55
563
0.84
0.16
22.9
13.1
—
—
—
0
0
20
180
1.16
0.15
3.2
2.7
5.87
375.81
e6/l
0.53
12
140
14
159
0.85
0.15
2.4
2.8
—
0.40
—
0
5
42
401
1.14
0.13
4.1
4.4
—
—
—
0
0
27
253
1.12
0.11
2.1
2.0
95.69
92.32
pmol/l
0.16
14
122
5
47
1.07
0.09
2.8
1.5
—
—
—
0
0
45
435
1.12
0.09
37.9
18.1
14.08
13.62
%
1.85
45
430
5
60
0.82
0.08
1.0
1.3
—
—
—
0
0
21
224
0.91
0.08
2.8
3.5
6.50
6.14
ph
—
8
132
21
216
0.96
0.00
2.6
3.7
28.09
58.89
mg/l
1.07
15
143
11
112
0.98
0.00
5.9
4.3
—
—
—
0
0
20
201
0.99
0.00
2.1
2.2
114.60
565.07
u/l
0.67
20
188
21
205
1.04
0.00
3.9
3.1
2.70
35.71
e6/l
2.58
12
146
35
345
1.03
0.00
3.5
3.9
—
48.86
—
0
7
22
218
1.01
0.00
3.2
4.6
12.86
9.18
mg/mmol
0.17
15
138
22
222
0.99
0.00
3.0
2.8
132.64
145.35
ug/l
0.18
22
210
5
51
0.98
0.00
3.8
2.4
7.40
7.38
ph
—
5
41
6
67
0.88
-0.00
4.2
3.6
4.33
1.91
mmol/l
—
6
52
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
33.00
—
0
6
5
55
0.90
-0.00
2.0
3.1
3.64
12.01
ug/l
—
5
49
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
4.90
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
0.80
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
13.33
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
2.50
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
329.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
5.88
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
249.60
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_OROPHARYNG – Malignant neoplasm of oropharyng

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).