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Other specified and unspecified disorders of conjunctiva

DOID EFO Endpoint Browser PheWeb

H7_CONJUNAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H11.8, H11.9
  • Hospital discharge: ICD-9 — 372[8-9]
  • Cause of death: ICD-10 — H11.8, H11.9
  • Cause of death: ICD-9 — 372[8-9]

2 out of 7 registries used, show all original rules.

428

4. Check minimum number of events

None

428

5. Include endpoints

None

428

6. Filter based on genotype QC (FinnGen only)

386

Control definitions (FinnGen only)

Control exclude
H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2409 1232 1163
Only index persons 2216 1153 1063
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 49.21 51.60 46.86
Only index persons 50.48 52.87 47.88

-FinnGen-

Key figures

All Female Male
Number of individuals 386 219 167
Unadjusted period prevalence (%) 0.08 0.08 0.08
Median age at first event (years) 58.59 56.85 60.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
398
Matched controls
3980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
+∞
259.8
220
*
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
1322.8
177.5
160
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
272.0
48.1
48
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
139.3
46.9
49
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
6.2
27.9
51
92
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
43.4
26.2
32
8
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
277.7
26.0
26
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.0
25.9
213
1100
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.0
24.5
173
816
H04.10
ICD-10 Finland
Dry eye syndrome
4.0
24.1
78
227
S01GX01
ATC
cromoglicic acid; ophthalmic
3.6
23.9
93
307
CD2S4
NOMESCO Finland
Photography of eye
77.2
19.9
22
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.1
15.9
75
275
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.3
15.8
44
113
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
15.7
15
*
H11.0
ICD-10 Finland
Pterygium
83.2
14.7
16
*
3728X
ICD-9 Finland
Disorders of conjunctiva, Other disorders of conjunctiva
+∞
14.7
14
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
155.5
14.6
15
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
5.4
11.9
24
47
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
11.7
93
442
H01.0
ICD-10 Finland
Blepharitis
3.4
11.6
43
135
XCK10
NOMESCO Finland
Photography of fundus of eye
3.0
11.4
54
197
F01
ICPC
Eye pain
4.9
10.9
24
51
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.9
10.8
55
209
H10.4
ICD-10 Finland
Chronic conjunctivitis
112.9
10.5
11
*
CFA12
NOMESCO Finland
Resection of conjunctiva
+∞
10.5
10
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.2
10.2
28
71
S01XA18
ATC
ciclosporin; ophthalmic
30.8
9.5
12
*
127
Kela drug reimbursment
Transplant complication
12.8
9.4
16
13
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
9.4
9
*
F29
ICPC
Eye symptom/complaint other
2.6
9.3
58
244
L04AA06
ATC
mycophenolic acid; systemic
9.4
9.1
18
20
H57.1
ICD-10 Finland
Ocular pain
3.8
8.7
27
75
S01GX09
ATC
olopatadine; ophthalmic
8.5
8.7
18
22
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
8.3
34
114
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.1
8.2
35
120
F02
ICPC
Red eye
3.5
7.7
27
82
H15.1
ICD-10 Finland
Episcleritis
9.1
7.6
15
17
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
7.4
295
2386
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.0
7.3
21
55
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
20.5
7.2
10
5
S01GX02
ATC
levocabastine; ophthalmic
3.8
7.1
22
61
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.1
95
548
WX002
NOMESCO Finland
Sedation and analgesia
2.0
7.0
81
442
CBA10
NOMESCO Finland
Biopsy of eyelid
11.2
6.8
12
11
Z94.0
ICD-10 Finland
Kidney transplant status
17.1
6.8
10
6
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
6.7
61
303
H16.0
ICD-10 Finland
Corneal ulcer
3.0
6.6
29
101
CGE55
NOMESCO Finland
Excision of pterygium with transplanation of conjunctiva
+∞
6.3
6
*
CFD10
NOMESCO Finland
Repair of conjunctiva
+∞
6.3
6
*
3729X
ICD-9 Finland
Disorders of conjunctiva, Unspecified disorder of conjunctiva
+∞
6.3
6
*
S01GX08
ATC
ketotifen; ophthalmic
4.2
6.1
16
39

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
267
1990
2.04
9.95
11.5
9.8
3.92
4.04
e9/l
0.45
239
1750
175
1146
1.94
9.34
8.7
5.8
—
—
—
0
0
212
1480
1.93
9.32
7.6
4.8
36.27
35.88
g/l
0.46
197
1411
241
1777
1.90
8.75
8.0
6.1
0.60
0.58
e9/l
0.66
212
1530
241
1784
1.89
8.57
8.0
6.1
0.04
0.04
e9/l
0.10
210
1535
244
1831
1.86
8.12
8.3
6.3
0.18
0.19
e9/l
0.03
218
1605
242
1815
1.85
8.03
8.2
6.1
1.85
1.93
e9/l
0.39
219
1606
114
677
1.96
7.88
5.7
3.8
905.38
271.07
ng/l
0.46
83
518
51
219
2.52
7.85
5.2
3.2
264.55
201.22
ng/l
0.34
51
201
158
1046
1.85
7.81
6.3
6.0
—
—
—
0
0
319
2636
2.06
7.66
5.4
4.1
14.82
14.78
pmol/l
0.13
294
2416
54
243
2.41
7.52
6.0
3.8
100.44
77.38
ng/l
0.60
44
212
211
1541
1.79
7.41
11.9
6.4
1.21
1.21
mmol/l
0.18
193
1438
135
890
1.78
6.54
3.0
2.7
344.21
340.25
umol/l
0.17
122
793
169
1194
1.72
6.38
4.9
3.3
2.35
2.35
mmol/l
0.13
155
1096
211
1584
1.71
6.37
12.7
12.2
1.17
1.22
inr
0.71
182
1305
216
1634
1.70
6.32
8.8
6.2
0.62
0.68
%
0.96
202
1535
28
99
2.97
6.24
2.5
2.4
11.24
12.87
mg/l
0.38
28
92
216
1642
1.69
6.14
8.8
6.2
9.08
8.83
%
0.59
203
1552
258
2060
1.72
6.08
8.5
4.9
6.59
6.58
mmol/l
0.02
245
1937
215
1640
1.68
5.97
9.1
6.1
2.73
2.75
%
0.04
201
1548
219
1679
1.68
5.96
9.0
6.2
27.89
27.69
%
0.09
207
1600
222
1711
1.67
5.90
14.0
7.0
1.22
1.21
mmol/l
0.75
190
1495
215
1649
1.66
5.78
8.9
6.1
57.26
57.35
%
0.04
204
1582
71
397
1.96
5.71
2.5
1.7
—
—
—
0
0
96
599
1.79
5.48
6.2
3.4
0.82
0.82
mmol/l
0.01
88
571
17
48
3.66
5.38
1.4
1.3
—
—
—
0
0
17
48
3.66
5.38
1.4
1.3
—
—
—
0
0
17
48
3.66
5.38
1.4
1.3
—
—
—
0
0
17
48
3.66
5.38
1.4
1.3
—
—
—
0
0
236
1879
1.63
5.27
8.6
6.6
10.96
11.06
umol/l
0.06
227
1797
374
3411
2.60
5.20
23.2
14.9
22.20
23.86
mg/l
0.46
309
2788
149
1068
1.63
5.05
7.4
4.0
7.40
7.40
ph
0.11
110
751
197
1515
1.59
4.97
2.9
2.5
79.21
77.14
nmol/l
0.46
179
1368
306
2623
1.72
4.93
11.1
8.0
78.96
80.03
u/l
0.19
296
2497
137
976
1.62
4.70
3.7
3.0
0.30
0.43
e6/l
0.59
102
708
145
1050
1.60
4.64
3.0
2.0
194.12
264.77
u/l
0.39
133
998
7
5
14.21
4.59
2.7
1.4
—
—
—
0
0
101
670
1.68
4.57
2.5
2.7
2.44
2.45
mmol/l
0.32
90
606
352
3166
1.97
4.56
6.7
5.0
1.81
1.89
mu/l
0.65
329
2928
355
3203
2.00
4.54
6.9
6.1
39.27
39.13
mmol/mol
0.11
333
3032
190
1474
1.55
4.46
2.6
2.0
95.25
95.73
pmol/l
0.05
103
753
16
50
3.29
4.38
1.2
1.2
—
—
—
0
0
78
489
1.74
4.32
3.1
2.1
—
—
—
0
0
70
426
1.78
4.29
2.0
1.5
—
—
—
0
0
118
827
1.61
4.27
3.6
3.5
—
0.22
—
0
9
206
1648
1.52
4.07
3.7
2.9
125.87
114.49
ug/l
0.35
195
1538
378
3518
2.48
4.05
20.5
13.3
—
—
—
0
0
112
786
1.59
4.00
3.6
1.6
2.09
1.41
mg/l
0.27
88
618
176
1368
1.51
3.96
2.5
2.1
—
—
—
0
0
13
32
4.16
3.93
1.1
1.4
—
—
—
0
0
19
71
2.76
3.88
1.9
1.4
117.46
155.71
au/ml
—
5
22
14
44
3.26
3.81
1.7
2.2
—
—
—
0
0
85
564
1.64
3.79
3.8
2.3
13.82
13.59
umol/l
0.08
80
526
135
999
1.53
3.79
2.1
1.6
23.22
20.35
nmol/l
0.79
121
830
57
340
1.79
3.73
3.2
2.3
52.71
171.64
u/l
0.40
45
289
150
1141
1.50
3.68
3.9
3.1
26.64
99.49
e6/l
0.67
117
868
82
544
1.64
3.65
2.8
2.9
3.63
2.19
e6/l
0.57
41
258
275
2368
1.52
3.63
5.8
4.2
—
1.61
—
0
5
21
86
2.52
3.61
2.4
3.0
7.00
2.10
index
0.57
12
53
133
992
1.51
3.56
4.3
3.2
1512.51
1131.54
ng/l
0.45
115
844
20
81
2.55
3.52
3.6
1.7
3.59
4.54
iu/l
—
10
31
65
410
1.70
3.50
3.7
3.0
7.52
7.65
umol/l
0.02
55
360
118
861
1.53
3.49
2.3
2.1
2.43
2.91
mg/l
2.19
103
758
389
3727
2.93
3.45
33.7
22.7
6.76
6.68
e9/l
0.19
381
3661
389
3727
2.93
3.45
33.6
22.7
4.48
4.51
e12/l
0.58
381
3662
389
3724
2.97
3.44
33.8
22.7
244.32
248.67
e9/l
0.76
383
3668
224
1862
1.46
3.44
4.2
3.6
0.00
0.00
estimate
-0.00
35
399
225
1874
1.46
3.41
4.2
3.6
0.09
0.00
estimate
0.49
33
373
167
1314
1.47
3.40
4.5
3.7
33.38
61.95
e6/l
0.76
123
918
6
7
8.68
3.27
2.0
1.0
—
—
—
0
0
6
7
8.68
3.27
4.0
3.6
0.62
0.60
mmol/l
—
6
7
19
78
2.51
3.26
2.0
1.4
—
—
—
0
0
79
535
1.59
3.23
1.8
1.7
1012.39
1187.41
nmol/l
1.15
64
400
72
479
1.61
3.16
3.9
2.3
24.69
23.10
%
0.39
67
453
68
447
1.63
3.13
1.8
1.6
—
—
—
0
0
67
439
1.63
3.13
3.4
2.9
3.84
4.94
e9/l
1.10
59
384
93
662
1.53
3.05
3.9
2.7
566.13
542.51
mosm/kgh2o
0.42
80
581
152
1196
1.44
3.01
4.1
3.2
7.20
7.70
mmol/l
0.95
130
1031
219
1844
1.42
2.95
4.1
3.5
0.00
0.00
estimate
0.50
36
390
47
285
1.74
2.92
1.5
1.6
—
—
—
0
0
9
22
4.16
2.90
3.7
3.3
581.22
622.18
u/ml
—
9
22
12
38
3.22
2.87
2.0
1.8
13.56
13.05
%
0.63
12
38
109
813
1.47
2.84
3.9
3.6
1.02
1.02
kg/l
0.06
71
520
105
781
1.47
2.76
3.3
2.5
5.10
5.12
e6/l
0.01
95
716
46
282
1.71
2.76
2.8
2.5
9.66
10.57
g/l
1.02
41
260
196
1634
1.39
2.72
4.2
2.7
—
—
estimate
—
0
0
75
524
1.53
2.66
3.9
2.3
2.25
2.35
g/l
0.82
70
487
14
55
2.60
2.64
1.4
1.3
—
—
—
0
0
125
969
1.42
2.63
6.9
4.1
—
—
—
0
0
49
311
1.66
2.60
1.4
1.4
—
—
—
0
0
11
36
3.11
2.58
1.4
1.3
—
—
—
0
0
72
502
1.53
2.58
1.5
1.4
551.43
486.55
titre
0.20
14
116
347
3220
1.61
2.58
4.4
4.2
1.30
1.28
mmol/l
0.22
321
2996
83
598
1.49
2.55
1.9
1.7
—
—
—
0
0
140
1113
1.40
2.54
4.6
2.6
56.88
64.89
u/l
0.64
130
1045
178
1475
1.37
2.50
3.9
3.2
6.14
6.18
ph
0.20
91
836
19
89
2.19
2.49
1.2
1.2
—
—
—
0
0
60
407
1.56
2.43
14.2
8.1
1.08
0.87
mmol/l
0.16
55
339
351
3278
1.60
2.39
5.5
4.9
5.99
5.92
mmol/l
0.41
326
3028
67
468
1.52
2.38
14.6
6.3
103.96
104.65
mmol/l
0.60
67
468
45
286
1.65
2.38
4.6
4.5
0.65
0.53
%
0.25
17
86
8
22
3.69
2.37
1.4
1.1
—
—
—
0
0
360
3384
1.67
2.37
5.2
4.8
1.45
1.46
mmol/l
0.28
338
3165
7
17
4.17
2.37
1.1
1.0
1334.43
1595.59
miu/ml
—
7
17
47
303
1.62
2.35
18.3
7.5
—
—
—
0
0
27
148
1.88
2.35
1.1
1.2
—
—
—
0
0
365
3447
1.71
2.31
6.2
5.6
2.67
2.73
mmol/l
0.68
347
3230
60
415
1.52
2.24
15.1
8.0
7.45
7.42
ph
2.91
32
246
5
9
5.61
2.22
1.2
1.3
—
—
—
0
0
360
3395
1.63
2.20
5.3
5.0
4.54
4.64
mmol/l
1.15
342
3187
49
325
1.58
2.19
1.6
1.4
—
—
—
0
0
107
831
1.39
2.19
6.6
4.9
—
—
—
0
0
9
30
3.05
2.16
2.0
1.7
8.80
11.21
%
—
9
30
34
207
1.70
2.12
8.3
3.0
24.21
24.38
mmol/l
0.12
34
207
10
37
2.75
2.08
1.6
1.1
—
—
—
0
0
161
1343
1.33
2.07
5.0
3.6
50.51
101.04
ng/l
0.47
103
928
43
283
1.58
2.00
1.2
1.2
—
—
—
0
0
20
105
1.95
1.99
1.2
1.2
—
—
—
0
0
23
127
1.86
1.98
1.3
1.3
—
—
—
0
0
18
91
2.02
1.98
1.1
1.1
—
—
—
0
0
64
462
1.46
1.95
1.7
2.5
91.47
128.04
ug/g
0.87
50
370
267
2406
1.33
1.95
4.0
3.3
52.22
45.41
u/l
0.43
250
2282
65
472
1.45
1.92
1.3
1.3
—
—
—
0
0
183
1568
1.31
1.91
11.7
11.0
0.00
0.00
e9/l
0.60
146
1288
7
22
3.22
1.89
1.1
2.1
13.64
12.58
umol/l
—
7
22
376
3606
1.77
1.87
16.2
11.5
26.36
26.60
u/l
0.10
367
3513
9
34
2.68
1.87
1.4
1.0
—
—
—
0
0
25
145
1.77
1.86
2.5
1.8
1.30
1.53
g/l
0.85
25
131
134
1111
1.31
1.75
3.3
2.3
—
—
—
0
0
48
337
1.48
1.69
9.5
3.1
1.74
1.93
mmol/l
0.16
43
281
15
76
2.01
1.66
1.4
1.3
258.00
222.35
u/ml
—
10
40
18
98
1.88
1.64
1.2
1.4
267.00
315.94
ug/g
0.43
11
58
23
136
1.73
1.62
1.4
1.2
—
—
—
0
0
90
712
1.34
1.62
2.2
1.9
—
—
—
0
0
44
307
1.49
1.60
4.7
4.4
0.93
1.06
%
0.17
15
96
134
1123
1.29
1.59
5.3
4.0
5.13
9.44
mg/mmol
1.33
90
712
49
350
1.46
1.59
9.6
3.2
7.38
7.38
ph
0.05
26
200
7
26
2.72
1.58
1.1
1.1
—
—
—
0
0
43
300
1.49
1.57
2.9
2.6
62.64
66.64
e9/l
0.40
33
224
35
234
1.54
1.55
1.1
1.2
148.91
139.19
u/ml
0.06
13
102
131
1101
1.28
1.51
4.5
3.4
24.82
52.45
mg/l
2.53
88
732
6
21
2.88
1.51
1.2
1.1
—
—
—
0
0
26
163
1.64
1.50
2.2
2.3
—
—
—
0
0
21
125
1.72
1.46
1.9
1.6
—
—
—
0
0
21
125
1.72
1.46
1.7
2.3
1768.75
6105.88
u/l
0.72
11
49
10
46
2.20
1.41
1.1
1.1
—
—
—
0
0
10
46
2.20
1.41
4.4
2.2
12.30
10.95
mmol/l
—
10
46
9
40
2.28
1.41
1.0
1.1
—
—
—
0
0
42
299
1.45
1.40
2.1
2.3
11.33
13.80
nmol/l
1.39
37
275
41
291
1.46
1.39
2.0
2.0
0.00
0.00
estimate
—
6
64
18
105
1.75
1.35
8.8
2.1
1171.89
684.59
ug/l
0.19
18
99
16
90
1.81
1.35
1.1
1.1
—
—
—
0
0
9
43
2.12
1.31
1.3
1.3
—
—
—
0
0
8
34
2.38
1.30
2.6
2.3
—
—
—
0
0
164
1443
1.23
1.24
2.0
1.9
1.23
1.38
mmol/l
2.15
143
1227
117
992
1.25
1.24
3.3
2.9
—
—
—
0
0
41
299
1.41
1.22
4.5
4.9
0.50
0.21
%
0.29
12
78
31
215
1.48
1.20
5.2
6.6
—
—
—
0
0
22
141
1.59
1.20
2.6
1.8
—
—
—
0
0
5
20
2.52
1.15
3.0
2.9
0.60
0.70
index
—
5
20
51
394
1.34
1.09
1.7
1.6
—
—
—
0
0
21
137
1.56
1.08
3.1
1.9
5.96
3.21
ug/l
0.29
21
127
124
1417
0.82
1.06
3.5
3.0
—
—
—
0
0
22
148
1.51
1.00
1.0
1.1
—
—
—
0
0
39
294
1.36
0.99
4.4
4.5
0.00
0.16
%
—
10
82
22
149
1.50
0.97
1.8
1.7
—
—
—
0
0
12
69
1.76
0.97
2.9
3.0
1.42
2.43
mmol/l
—
6
43
14
86
1.65
0.92
2.0
2.1
128.67
130.75
g/l
—
9
64
26
186
1.43
0.90
7.3
2.2
0.50
0.61
%
1.36
26
186
23
161
1.45
0.88
1.8
1.6
—
—
—
0
0
158
1424
1.18
0.87
4.3
3.4
0.00
0.02
estimate
0.80
33
331
6
30
2.01
0.87
1.3
1.1
—
—
—
0
0
8
45
1.79
0.84
1.0
1.4
—
—
nmol/l
—
0
0
23
163
1.44
0.84
1.8
1.6
—
—
—
0
0
23
163
1.44
0.84
1.8
1.6
—
—
—
0
0
23
163
1.44
0.84
1.8
1.6
—
—
—
0
0
78
662
1.22
0.82
1.4
1.3
10.45
30.19
iu/ml
5.17
22
210
6
32
1.89
0.82
1.2
1.0
—
—
—
0
0
98
858
1.19
0.75
1.4
1.3
0.61
1.12
u/ml
1.85
18
257
89
773
1.19
0.74
1.6
1.4
2.47
2.41
g/l
0.04
52
478
49
400
1.26
0.74
1.5
1.5
—
—
—
0
0
12
76
1.60
0.72
2.4
1.7
—
—
—
0
0
5
26
1.93
0.71
2.0
2.2
1906.00
1991.35
ml
—
5
26
12
77
1.58
0.69
3.7
2.5
—
—
—
0
0
11
69
1.61
0.69
1.2
1.3
—
—
—
0
0
5
27
1.86
0.68
1.6
1.1
94.60
101.78
pmol/l
—
5
27
17
119
1.45
0.68
2.1
1.9
—
—
—
0
0
5
92
0.54
0.68
1.0
1.3
—
—
—
0
0
46
378
1.25
0.66
1.8
1.8
—
—
—
0
0
19
138
1.40
0.63
1.3
1.4
217.00
235.05
miu/ml
—
6
64
75
652
1.19
0.63
2.4
3.0
0.57
0.76
ug/l
2.57
51
391
77
671
1.18
0.63
1.5
1.8
187879191.09
20708400.29
pmol/l
0.42
66
565
44
363
1.24
0.62
3.1
4.3
100.84
19.24
ug/l
0.45
34
301
0
20
0.00
0.60
0.0
2.0
—
7.63
—
0
20
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.8
—
16.70
—
0
22
10
64
1.58
0.59
2.5
2.1
5.55
5.05
mmol/24h
—
10
55
8
55
1.46
0.56
1.4
1.3
—
—
—
0
0
15
107
1.42
0.56
2.2
3.5
1.20
1.94
ratio
—
9
62
118
1075
1.14
0.54
4.4
5.1
1.49
2.21
ug/l
1.60
109
973
69
609
1.16
0.50
1.3
1.3
7.61
9.93
u/ml
0.13
29
246
7
47
1.50
0.48
1.7
3.1
—
—
—
0
0
112
1026
1.13
0.48
1.6
1.5
—
—
—
0
0
29
238
1.24
0.45
1.4
1.2
—
—
—
0
0
7
50
1.41
0.45
1.0
1.3
0.16
0.17
nmol/l
—
7
35
31
371
0.82
0.45
1.1
1.4
—
—
—
0
0
8
57
1.41
0.42
1.3
1.3
199.72
18.66
u/l
—
8
50
25
204
1.24
0.41
1.3
1.2
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
5.26
—
0
15
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
5
34
1.48
0.40
1.4
1.1
—
—
—
0
0
8
60
1.34
0.40
1.1
1.1
—
—
—
0
0
8
60
1.34
0.40
1.1
1.1
—
—
—
0
0
8
61
1.32
0.39
1.0
1.0
—
—
—
0
0
10
71
1.42
0.39
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.9
87.78
89.63
%
—
5
36
12
158
0.75
0.38
1.6
1.7
—
—
—
0
0
15
116
1.30
0.37
1.6
1.7
52.64
11.49
u/ml
—
5
28
5
37
1.36
0.37
2.2
2.7
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
1.80
1.37
u/ml
—
5
16
26
309
0.83
0.36
1.8
1.8
3.41
3.48
mmol/l
0.12
18
232
32
273
1.19
0.36
2.3
2.6
0.33
0.17
e6/l
0.52
32
260
33
283
1.18
0.35
5.7
4.1
7.31
7.34
ph
0.39
17
208
6
43
1.40
0.35
1.3
1.2
—
—
—
0
0
13
167
0.77
0.35
7.8
3.7
—
—
—
0
0
6
44
1.37
0.34
4.5
3.3
—
—
—
0
0
31
267
1.17
0.32
1.8
2.1
5.97
6.07
ph
0.20
17
179
52
467
1.13
0.32
1.2
1.2
—
—
—
0
0
15
120
1.26
0.30
1.9
2.9
—
—
—
0
0
14
111
1.27
0.30
8.1
8.7
—
—
—
0
0
20
234
0.85
0.25
6.6
3.4
5.14
5.09
kpa
0.12
20
229
10
78
1.29
0.24
1.5
1.8
—
—
—
0
0
5
38
1.32
0.23
3.2
3.0
—
—
—
0
0
15
125
1.21
0.22
5.6
3.6
195.00
252.13
mg/l
—
7
53
0
11
0.00
0.21
0.0
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
19.85
—
0
10
0
10
0.00
0.21
0.0
1.5
—
10.99
—
0
10
0
13
0.00
0.21
0.0
1.1
—
1.88
—
0
5
0
13
0.00
0.21
0.0
2.7
—
39.86
—
0
7
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
1.30
—
0
9
6
51
1.18
0.19
1.0
1.5
0.19
0.40
nmol/l
—
6
39
6
52
1.16
0.19
4.2
3.5
1.50
1.15
%
—
6
47
21
185
1.14
0.18
1.1
1.1
—
—
—
0
0
5
67
0.74
0.17
1.0
1.3
—
—
—
0
0
8
68
1.18
0.16
1.4
1.6
—
—
—
0
0
6
79
0.76
0.15
10.0
3.2
56.50
60.15
%
—
6
79
6
80
0.75
0.15
5.8
3.9
—
—
—
0
0
41
390
1.06
0.09
1.3
1.4
—
—
—
0
0
6
57
1.05
0.08
8.5
3.4
3.39
4.61
e9/l
—
6
57
6
57
1.05
0.08
1.3
1.3
—
72.54
—
0
5
8
74
1.08
0.07
9.9
1.5
0.92
0.97
nmol/l
—
8
64
25
235
1.07
0.07
1.5
2.5
—
—
—
0
0
8
78
1.03
0.07
1.6
1.5
—
—
—
0
0
14
131
1.07
0.03
1.6
1.2
0.87
0.91
g/l
0.23
14
131
19
181
1.05
0.03
1.2
1.6
0.31
0.32
mg/l
—
8
82
12
128
0.94
0.02
1.4
1.1
1.51
1.54
g/l
0.16
12
128
106
1050
1.01
0.02
4.0
3.0
0.00
0.01
estimate
0.74
33
324
30
292
1.03
0.02
6.0
3.4
—
—
—
0
0
11
117
0.94
0.01
1.5
1.2
—
3.51
—
0
12
15
151
0.99
0.00
6.1
5.0
36.86
36.93
°c
0.38
15
151
103
1035
0.99
0.00
5.4
3.7
0.00
0.01
estimate
0.99
33
367
0
5
0.00
0.00
0.0
2.6
—
6.12
—
0
5
6
65
0.92
0.00
10.3
3.0
11.55
9.33
pmol/l
—
6
65
0
5
0.00
0.00
0.0
1.4
—
76.88
—
0
5
0
5
0.00
0.00
0.0
1.8
—
402.00
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
16.28
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
64.00
—
0
8
0
7
0.00
-0.00
0.0
6.0
—
11.43
—
0
7
8
86
0.93
-0.00
1.9
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
42.00
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
40.00
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
1.17
—
0
8
5
56
0.89
-0.00
2.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.02
—
0
8
8
81
0.99
-0.00
1.8
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
69
0.87
-0.00
2.7
1.7
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CONJUNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONJUNAS 0.931 [0.7, 1.24] 0.623
Birth year 0.999 [0.99, 1.01] 0.831

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 895 females with H7_CONJUNAS died.

Males

Parameter HR [95% CI] p-value
H7_CONJUNAS 1.148 [0.85, 1.55] 0.366
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 871 males with H7_CONJUNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUNAS.

N-year risk Females Males
1 0.09% 0.194%
5 0.57% 1.137%
10 1.522% 2.871%
15 3.012% 5.649%
20 5.316% 9.392%

Relationships between endpoints

↥

Index endpoint: H7_CONJUNAS – Other specified and unspecified disorders of conjunctiva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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