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Klinefelter syndrome, karyotype 47 XXY

Endpoint Browser

Q17_KLINEFELTER_SYNDROME

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q98.0
  • Cause of death: ICD-10 — Q98.0

2 out of 7 registries used, show all original rules.

79

4. Check minimum number of events

None

79

5. Include endpoints

None

79

6. Filter based on genotype QC (FinnGen only)

24

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 24 - 21
Unadjusted period prevalence (%) 0.01 - 0.01
Median age at first event (years) 22.78 - 21.43

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
79
Matched controls
790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q980, ,
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
+∞
113.6
79
*
A98, ,
ICD-O-3
+∞
110.7
78
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
85.7
66
*
J01DB01, ,
ATC
cefalexin; oral
+∞
84.0
65
*
WX110, ,
ICD-O-3
+∞
82.2
64
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
80.5
63
*
SAA01, ,
ICD-O-3
+∞
72.4
58
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
72.4
58
*
K021, ,
ICD-O-3
+∞
63.2
52
*
SAA02, ,
ICD-O-3
+∞
63.2
52
*
G03BA03, ,
ATC
testosterone; systemic, rectal, sublingual, transdermal
+∞
61.8
51
*
SFA10, ,
ICD-O-3
+∞
60.3
50
*
WX290, ,
ICD-O-3
+∞
57.5
48
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
57.5
48
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
57.5
48
*
SFA20, ,
ICD-O-3
+∞
56.1
47
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
53.3
45
*
121, ,
Kela drug reimbursment
Severe hypofunction of sexual glands
+∞
51.9
44
*
EB1AA, ,
ICD-O-3
+∞
50.5
43
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
49.2
42
*
EBA00, ,
ICD-O-3
+∞
46.5
40
*
KMAK, ,
ICD-O-3
+∞
46.5
40
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
45.2
39
*
M03BX02, ,
ATC
tizanidine; oral
+∞
43.9
38
*
J069, ,
ICD-O-3
+∞
43.9
38
*
R06AE07, ,
ATC
cetirizine; oral
+∞
43.9
38
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
43.9
38
*
WYA05, ,
ICD-O-3
+∞
43.9
38
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
42.6
37
*
J01DA01, ,
ATC
[U] cefalexin
+∞
42.6
37
*
EB1HA, ,
ICD-O-3
+∞
42.6
37
*
SPAT1256, ,
ICD-O-3
+∞
41.3
36
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
41.3
36
*
R01AD09, ,
ATC
mometasone; nasal
+∞
41.3
36
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
40.0
35
*
Z012, ,
ICD-O-3
+∞
38.8
34
*
SAA03, ,
ICD-O-3
+∞
38.8
34
*
EB1SA, ,
ICD-O-3
+∞
37.5
33
*
WZC00, ,
ICD-O-3
+∞
37.5
33
*
-1, ,
ICD-O-3
+∞
35.0
31
*
GD1AA, ,
ICD-O-3
+∞
35.0
31
*
Q980, ,
ICD-O-3
+∞
33.8
30
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
33.8
30
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
33.8
30
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
32.6
29
*
R06AX27, ,
ATC
desloratadine; oral
+∞
31.3
28
*
SFA30, ,
ICD-O-3
+∞
31.3
28
*
S18, ,
ICD-O-3
+∞
31.3
28
*
Z315, ,
ICD-10 Finland
Genetic counselling
+∞
31.3
28
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
31.3
28
*
R74, ,
ICD-O-3
+∞
30.1
27
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
28.9
26
*
SCA01, ,
ICD-O-3
+∞
28.9
26
*
M796, ,
ICD-O-3
+∞
27.7
25
*
WZB00, ,
ICD-O-3
+∞
27.7
25
*
SPAT1263, ,
ICD-O-3
+∞
27.7
25
*
SDA02, ,
ICD-O-3
+∞
27.7
25
*
Q984, ,
ICD-10 Finland
Klinefelter syndrome, unspecified
+∞
27.7
25
*
Z871, ,
ICD-O-3
+∞
26.5
24
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
26.5
24
*
E0000UV, ,
ATC
+∞
26.5
24
*
M545, ,
ICD-O-3
+∞
26.5
24
*
WX408, ,
ICD-O-3
+∞
26.5
24
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
26.5
24
*
SDA03, ,
ICD-O-3
+∞
26.5
24
*
N05AH04, ,
ATC
quetiapine; oral
+∞
25.4
23
*
D82, ,
ICD-O-3
+∞
25.4
23
*
N46, ,
ICD-10 Finland
Male infertility
+∞
25.4
23
*
R21, ,
ICD-O-3
+∞
25.4
23
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
25.4
23
*
C07AA05, ,
ATC
propranolol; systemic
+∞
25.4
23
*
K045, ,
ICD-O-3
+∞
24.2
22
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
24.2
22
*
SPAT1249, ,
ICD-O-3
+∞
24.2
22
*
OAB43, ,
ICD-O-3
+∞
24.2
22
*
SPAT1301, ,
ICD-O-3
+∞
24.2
22
*
ZXE10, ,
ICD-O-3
+∞
23.0
21
*
SPAT1253, ,
ICD-O-3
+∞
23.0
21
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
23.0
21
*
R05, ,
ICD-O-3
+∞
23.0
21
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
23.0
21
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
23.0
21
*
L17, ,
ICD-O-3
+∞
23.0
21
*
SPAT1310, ,
ICD-O-3
+∞
23.0
21
*
Z3231, ,
ICD-O-3
+∞
23.0
21
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
21.9
20
*
ZXD10, ,
ICD-O-3
+∞
21.9
20
*
D19, ,
ICD-O-3
+∞
21.9
20
*
SFC01, ,
ICD-O-3
+∞
21.9
20
*
VALMI, ,
ICD-O-3
+∞
21.9
20
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
21.9
20
*
ZXE00, ,
ICD-O-3
+∞
20.7
19
*
R83, ,
ICD-O-3
+∞
20.7
19
*
E291, ,
ICD-10 Finland
Testicular hypofunction
+∞
20.7
19
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
20.7
19
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
20.7
19
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
20.7
19
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
19.6
18
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
19.6
18
*
L03, ,
ICD-O-3
+∞
19.6
18
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
19.6
18
*
WVA30, ,
ICD-O-3
+∞
19.6
18
*
EBA05, ,
ICD-O-3
+∞
19.6
18
*
N05CF02, ,
ATC
zolpidem; oral
+∞
19.6
18
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
19.6
18
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
18.4
17
*
R4110, ,
ICD-O-3
+∞
18.4
17
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
18.4
17
*
D07AC01, ,
ATC
betamethasone; topical
+∞
18.4
17
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
18.4
17
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
18.4
17
*
SPAT1283, ,
ICD-O-3
+∞
18.4
17
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
18.4
17
*
WZA90, ,
ICD-O-3
+∞
18.4
17
*
Z3226, ,
ICD-O-3
+∞
18.4
17
*
SPAT1223, ,
ICD-O-3
+∞
18.4
17
*
K0364, ,
ICD-O-3
+∞
18.4
17
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
18.4
17
*
Z760, ,
ICD-O-3
+∞
17.3
16
*
P01, ,
ICD-O-3
+∞
17.3
16
*
SGA01, ,
ICD-O-3
+∞
17.3
16
*
SDA01, ,
ICD-O-3
+∞
17.3
16
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
17.3
16
*
N06AB04, ,
ATC
citalopram; systemic
+∞
17.3
16
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
17.3
16
*
SDA04, ,
ICD-O-3
+∞
17.3
16
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
17.3
16
*
Q984, ,
ICD-O-3
+∞
17.3
16
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
16.2
15
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
16.2
15
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
16.2
15
*
N06AB10, ,
ATC
escitalopram; oral
+∞
16.2
15
*
Z2221, ,
ICD-O-3
+∞
16.2
15
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
16.2
15
*
D01BA02, ,
ATC
terbinafine; oral
+∞
16.2
15
*
M02AA07, ,
ATC
piroxicam; topical
+∞
16.2
15
*
M544, ,
ICD-O-3
+∞
16.2
15
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
16.2
15
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
16.2
15
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
16.2
15
*
A97, ,
ICD-O-3
+∞
15.1
14
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
15.1
14
*
K0382, ,
ICD-O-3
+∞
15.1
14
*
E000001, ,
ATC
+∞
15.1
14
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
15.1
14
*
L12, ,
ICD-O-3
+∞
15.1
14
*
D11, ,
ICD-O-3
+∞
15.1
14
*
OAA65, ,
ICD-O-3
+∞
15.1
14
*
T90, ,
ICD-O-3
+∞
15.1
14
*
L01, ,
ICD-O-3
+∞
15.1
14
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
15.1
14
*
ZXD05, ,
ICD-O-3
+∞
15.1
14
*
I10, ,
ICD-O-3
+∞
15.1
14
*
A03, ,
ICD-O-3
+∞
15.1
14
*
A10BA02, ,
ATC
metformin; oral
+∞
15.1
14
*
J010, ,
ICD-O-3
+∞
15.1
14
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
15.1
14
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
14.0
13
*
Y28, ,
ICD-O-3
+∞
14.0
13
*
WX105, ,
ICD-O-3
+∞
14.0
13
*
AA1AD, ,
ICD-O-3
+∞
14.0
13
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
14.0
13
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
14.0
13
*
C10AA01, ,
ATC
simvastatin; oral
+∞
14.0
13
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
14.0
13
*
SPAT1325, ,
ICD-O-3
+∞
14.0
13
*
SPAT1315, ,
ICD-O-3
+∞
14.0
13
*
R06AE09, ,
ATC
levocetirizine; oral
+∞
14.0
13
*
SPAT1312, ,
ICD-O-3
+∞
14.0
13
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
14.0
13
*
F510, ,
ICD-O-3
+∞
14.0
13
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
14.0
13
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
14.0
13
*
N01, ,
ICD-O-3
+∞
14.0
13
*
K0365, ,
ICD-O-3
+∞
14.0
13
*
U072, ,
ICD-O-3
+∞
14.0
13
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
14.0
13
*
ZXA00, ,
ICD-O-3
+∞
14.0
13
*
N05BA04, ,
ATC
oxazepam; oral
+∞
14.0
13
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
12.8
12
*
R03CC02, ,
ATC
salbutamol; systemic
+∞
12.8
12
*
R5180, ,
ICD-10 Finland
Headache
+∞
12.8
12
*
OAB48, ,
ICD-O-3
+∞
12.8
12
*
EBA10, ,
ICD-O-3
+∞
12.8
12
*
R03DC03, ,
ATC
montelukast; oral
+∞
12.8
12
*
ZXA05, ,
ICD-O-3
+∞
12.8
12
*
S29, ,
ICD-O-3
+∞
12.8
12
*
WX002, ,
ICD-O-3
+∞
12.8
12
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
12.8
12
*
FM1EE, ,
ICD-O-3
+∞
12.8
12
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
12.8
12
*
N05CF01, ,
ATC
zopiclone; oral
+∞
12.8
12
*
J01DA08, ,
ATC
[U] cefaclor
+∞
12.8
12
*
K020, ,
ICD-O-3
+∞
12.8
12
*
R03AC03, ,
ATC
terbutaline; inhalant
+∞
12.8
12
*
SPAT1149, ,
ICD-O-3
+∞
11.7
11
*
F3210, ,
ICD-10 Finland
Moderate depressive episode without somatic syndrome
+∞
11.7
11
*
SPAT1306, ,
ICD-O-3
+∞
11.7
11
*
J01AA07, ,
ATC
tetracycline; systemic
+∞
11.7
11
*
A29, ,
ICD-O-3
+∞
11.7
11
*
SXC05, ,
ICD-O-3
+∞
11.7
11
*
SPAT1254, ,
ICD-O-3
+∞
11.7
11
*
L16, ,
ICD-O-3
+∞
11.7
11
*
R06AX13, ,
ATC
loratadine; oral
+∞
11.7
11
*
A09, ,
ICD-O-3
+∞
11.7
11
*
Z2446, ,
ICD-O-3
+∞
11.7
11
*
J450, ,
ICD-10 Finland
Predominantly allergic asthma
+∞
11.7
11
*
SPAT1240, ,
ICD-O-3
+∞
11.7
11
*
SPAT1260, ,
ICD-O-3
+∞
11.7
11
*
S21, ,
ICD-O-3
+∞
11.7
11
*
K040, ,
ICD-O-3
+∞
11.7
11
*
Z712, ,
ICD-10 Finland
Person consulting for explanation of investigation findings
+∞
11.7
11
*
WYA30, ,
ICD-O-3
+∞
11.7
11
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
11.7
11
*
P06, ,
ICD-O-3
+∞
11.7
11
*
P03, ,
ICD-O-3
+∞
11.7
11
*
SPAT1250, ,
ICD-O-3
+∞
11.7
11
*
WW200, ,
ICD-O-3
+∞
10.6
10
*
L02, ,
ICD-O-3
+∞
10.6
10
*
N03AX16, ,
ATC
[U] pregabalin
+∞
10.6
10
*
M545, ,
ICD-10 Finland
Low back pain
+∞
10.6
10
*
U071, ,
ICD-O-3
+∞
10.6
10
*
R060, ,
ICD-O-3
+∞
10.6
10
*
AA1BG, ,
ICD-O-3
+∞
10.6
10
*
E780, ,
ICD-O-3
+∞
10.6
10
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
10.6
10
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
10.6
10
*
R104, ,
ICD-O-3
+∞
10.6
10
*
JN3AE, ,
ICD-O-3
+∞
10.6
10
*
N06AX21, ,
ATC
duloxetine; oral
+∞
10.6
10
*
XF400, ,
ICD-O-3
+∞
10.6
10
*
Z0389, ,
ICD-10 Finland
Observation for other suspected diseases and conditions
+∞
10.6
10
*
E6601, ,
ICD-10 Finland
Obesity due to excess calories
+∞
10.6
10
*
M01AX17, ,
ATC
nimesulide; oral
+∞
10.6
10
*
OAA67, ,
ICD-O-3
+∞
10.6
10
*
R03BA01, ,
ATC
beclometasone; inhalant
+∞
10.6
10
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
10.6
10
*
D07AC13, ,
ATC
mometasone; topical
+∞
9.6
9
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
9.6
9
*
WX404, ,
ICD-O-3
+∞
9.6
9
*
D10, ,
ICD-O-3
+∞
9.6
9
*
B01AA03, ,
ATC
warfarin; systemic
+∞
9.6
9
*
D07BA04, ,
ATC
hydrocortisone and antiseptics; topical
+∞
9.6
9
*
D07AD01, ,
ATC
clobetasol; topical
+∞
9.6
9
*
SPAT1148, ,
ICD-O-3
+∞
9.6
9
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
9.6
9
*
SPAT1363, ,
ICD-O-3
+∞
9.6
9
*
FM1AE, ,
ICD-O-3
+∞
9.6
9
*
K0510, ,
ICD-O-3
+∞
9.6
9
*
N02AE01, ,
ATC
buprenorphine; parenteral, sublingual, transdermal
+∞
9.6
9
*
M531, ,
ICD-O-3
+∞
9.6
9
*
ZXE11, ,
ICD-O-3
+∞
9.6
9
*
K0408, ,
ICD-O-3
+∞
9.6
9
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
9.6
9
*
L309, ,
ICD-O-3
+∞
9.6
9
*
A55, ,
ICD-O-3
+∞
9.6
9
*
R5110, ,
ICD-O-3
+∞
9.6
9
*
C08CA01, ,
ATC
amlodipine; oral
+∞
9.6
9
*
E119, ,
ICD-O-3
+∞
9.6
9
*
A46, ,
ICD-10 Finland
Erysipelas
+∞
9.6
9
*
R02, ,
ICD-O-3
+∞
9.6
9
*
A50, ,
ICD-O-3
+∞
9.6
9
*
P29, ,
ICD-O-3
+∞
9.6
9
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
9.6
9
*
M255, ,
ICD-10 Finland
Pain in joint
+∞
9.6
9
*
L11, ,
ICD-O-3
+∞
9.6
9
*
PH2AE, ,
ICD-O-3
+∞
9.6
9
*
F329, ,
ICD-10 Finland
Depressive episode, unspecified
+∞
9.6
9
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
9.6
9
*
UJD10, ,
ICD-O-3
+∞
9.6
9
*
SPAT1262, ,
ICD-O-3
+∞
9.6
9
*
R5140, ,
ICD-O-3
+∞
9.6
9
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
9.6
9
*
S04, ,
ICD-O-3
+∞
9.6
9
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
9.6
9
*
M511, ,
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
+∞
9.6
9
*
Z024, ,
ICD-O-3
+∞
9.6
9
*
E11, ,
ICD-O-3
+∞
9.6
9
*
M771, ,
ICD-O-3
+∞
9.6
9
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
9.6
9
*
L15, ,
ICD-O-3
+∞
9.6
9
*
Z712, ,
ICD-O-3
+∞
9.6
9
*
SFA40, ,
ICD-O-3
+∞
9.6
9
*
TPH04, ,
ICD-O-3
+∞
9.6
9
*
J459, ,
ICD-O-3
+∞
9.6
9
*
A46, ,
ICD-O-3
+∞
9.6
9
*
D01, ,
ICD-O-3
+∞
9.6
9
*
D07BB04, ,
ATC
hydrocortisone butyrate and antiseptics; topical
+∞
9.6
9
*
J459, ,
ICD-10 Finland
Asthma, unspecified
+∞
9.6
9
*
Z011, ,
ICD-10 Finland
Examination of ears and hearing
+∞
8.5
8
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
8.5
8
*
Z000, ,
ICD-O-3
+∞
8.5
8
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
8.5
8
*
K021, ,
ICD-10 Finland
Caries of dentine
+∞
8.5
8
*
EBA15, ,
ICD-O-3
+∞
8.5
8
*
R074, ,
ICD-O-3
+∞
8.5
8
*
Z016, ,
ICD-O-3
+∞
8.5
8
*
ZXE20, ,
ICD-O-3
+∞
8.5
8
*
L08, ,
ICD-O-3
+∞
8.5
8
*
E000002, ,
ATC
+∞
8.5
8
*
SBB10, ,
ICD-O-3
+∞
8.5
8
*
SFA00, ,
ICD-O-3
+∞
8.5
8
*
Z508, ,
ICD-10 Finland
Care involving use of other rehabilitation procedures
+∞
8.5
8
*
L02BG04, ,
ATC
letrozole; oral
+∞
8.5
8
*
Z048, ,
ICD-10 Finland
Examination and observation for other specified reasons
+∞
8.5
8
*
KF8AE, ,
ICD-O-3
+∞
8.5
8
*
R101, ,
ICD-O-3
+∞
8.5
8
*
EB1VA, ,
ICD-O-3
+∞
8.5
8
*
A04, ,
ICD-O-3
+∞
8.5
8
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
8.5
8
*
J45, ,
ICD-O-3
+∞
8.5
8
*
G473, ,
ICD-O-3
+∞
8.5
8
*
SPAT1153, ,
ICD-O-3
+∞
8.5
8
*
KFB01, ,
ICD-O-3
+∞
8.5
8
*
SDE03, ,
ICD-O-3
+∞
8.5
8
*
T36, ,
ICD-10 Finland
Poisoning by systemic antibiotics
+∞
8.5
8
*
J3010, ,
ICD-10 Finland
Allergic rhinitis due to pollen
+∞
8.5
8
*
J209, ,
ICD-O-3
+∞
8.5
8
*
ZY010, ,
ICD-O-3
+∞
8.5
8
*
C09CA01, ,
ATC
losartan; oral
+∞
8.5
8
*
A28, ,
ICD-O-3
+∞
8.5
8
*
R06AX22, ,
ATC
ebastine; oral
+∞
8.5
8
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
8.5
8
*
I872, ,
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
+∞
8.5
8
*
M01AH01, ,
ATC
celecoxib; oral
+∞
8.5
8
*
H609, ,
ICD-O-3
+∞
8.5
8
*
P76, ,
ICD-O-3
+∞
8.5
8
*
SPAT1211, ,
ICD-O-3
+∞
8.5
8
*
M255, ,
ICD-O-3
+∞
8.5
8
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
8.5
8
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
8.5
8
*
A05, ,
ICD-O-3
+∞
8.5
8
*
S610, ,
ICD-10 Finland
Open wound of finger(s) without damage to nail
+∞
8.5
8
*
NA3BG, ,
ICD-O-3
+∞
8.5
8
*
GD1QA, ,
ICD-O-3
+∞
8.5
8
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
8.5
8
*
A99, ,
ICD-O-3
+∞
8.5
8
*
E6600, ,
ICD-10 Finland
Metabolic syndrome
+∞
8.5
8
*
M02AA10, ,
ATC
ketoprofen; topical
+∞
8.5
8
*
S060, ,
ICD-10 Finland
Concussion
+∞
7.4
7
*
NA3AA, ,
ICD-O-3
+∞
7.4
7
*
R2130, ,
ICD-O-3
+∞
7.4
7
*
NG1AA, ,
ICD-O-3
+∞
7.4
7
*
SPAT1321, ,
ICD-O-3
+∞
7.4
7
*
J20, ,
ICD-O-3
+∞
7.4
7
*
B01AF01, ,
ATC
rivaroxaban; oral
+∞
7.4
7
*
WVA20, ,
ICD-O-3
+∞
7.4
7
*
M791, ,
ICD-O-3
+∞
7.4
7
*
SAB03, ,
ICD-O-3
+∞
7.4
7
*
L29, ,
ICD-O-3
+∞
7.4
7
*
ZYC01, ,
ICD-O-3
+∞
7.4
7
*
SGB10, ,
ICD-O-3
+∞
7.4
7
*
SGA03, ,
ICD-O-3
+∞
7.4
7
*
H920, ,
ICD-O-3
+∞
7.4
7
*
XQ800, ,
ICD-O-3
+∞
7.4
7
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
7.4
7
*
N03AG01, ,
ATC
valproic acid; systemic, rectal
+∞
7.4
7
*
ZXE06, ,
ICD-O-3
+∞
7.4
7
*
R96, ,
ICD-O-3
+∞
7.4
7
*
ZXE05, ,
ICD-O-3
+∞
7.4
7
*
C09CA06, ,
ATC
candesartan; oral
+∞
7.4
7
*
SDE02, ,
ICD-O-3
+∞
7.4
7
*
UKC02, ,
ICD-O-3
+∞
7.4
7
*
XF600, ,
ICD-O-3
+∞
7.4
7
*
E119, ,
ICD-10 Finland
Type 2 diabetes mellitus, without complications
+∞
7.4
7
*
A01, ,
ICD-O-3
+∞
7.4
7
*
T28, ,
ICD-O-3
+∞
7.4
7
*
ZXE04, ,
ICD-O-3
+∞
7.4
7
*
L05, ,
ICD-O-3
+∞
7.4
7
*
Z314, ,
ICD-10 Finland
Procreative investigation and testing
+∞
7.4
7
*
SPAT1156, ,
ICD-O-3
+∞
7.4
7
*
Z001, ,
ICD-O-3
+∞
7.4
7
*
N05AX08, ,
ATC
risperidone; systemic
+∞
7.4
7
*
A23, ,
ICD-O-3
+∞
7.4
7
*
H01, ,
ICD-O-3
+∞
7.4
7
*
Q981, ,
ICD-10 Finland
Klinefelter syndrome, male with more than two X chromosomes
+∞
7.4
7
*
SPAT1033, ,
ICD-O-3
+∞
7.4
7
*
G04CA01, ,
ATC
alfuzosin; oral
+∞
7.4
7
*
J01DA06, ,
ATC
[U] cefuroxime
+∞
7.4
7
*
SGC10, ,
ICD-O-3
+∞
7.4
7
*
N06AB06, ,
ATC
sertraline; oral
+∞
7.4
7
*
Z718, ,
ICD-O-3
+∞
7.4
7
*
F101, ,
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
+∞
7.4
7
*
K081, ,
ICD-O-3
+∞
7.4
7
*
SPAT1216, ,
ICD-O-3
+∞
7.4
7
*
Z113, ,
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
+∞
7.4
7
*
M549, ,
ICD-O-3
+∞
7.4
7
*
F29, ,
ICD-O-3
+∞
7.4
7
*
E291, ,
ICD-O-3
+∞
7.4
7
*
K0530, ,
ICD-O-3
+∞
7.4
7
*
SPAT1316, ,
ICD-O-3
+∞
7.4
7
*
OAA80, ,
ICD-O-3
+∞
7.4
7
*
SCA02, ,
ICD-O-3
+∞
7.4
7
*
D07CC01, ,
ATC
betamethasone and antibiotics; topical
+∞
7.4
7
*
M546, ,
ICD-O-3
+∞
7.4
7
*
P74, ,
ICD-O-3
+∞
7.4
7
*
E000006, ,
ATC
+∞
7.4
7
*
N06AB05, ,
ATC
paroxetine; oral
+∞
6.3
6
*
L309, ,
ICD-10 Finland
Dermatitis, unspecified
+∞
6.3
6
*
M54, ,
ICD-O-3
+∞
6.3
6
*
R55, ,
ICD-10 Finland
Syncope and collapse
+∞
6.3
6
*
R01BA51, ,
ATC
phenylpropanolamine, combinations; oral
+∞
6.3
6
*
T99, ,
ICD-O-3
+∞
6.3
6
*
J3010, ,
ICD-O-3
+∞
6.3
6
*
112, ,
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
6.3
6
*
H81, ,
ICD-O-3
+∞
6.3
6
*
ZXD20, ,
ICD-O-3
+∞
6.3
6
*
R4120, ,
ICD-O-3
+∞
6.3
6
*
A06AD11, ,
ATC
lactulose; oral
+∞
6.3
6
*
H13, ,
ICD-O-3
+∞
6.3
6
*
F329, ,
ICD-O-3
+∞
6.3
6
*
OAB93, ,
ICD-O-3
+∞
6.3
6
*
-44, ,
ICD-O-3
+∞
6.3
6
*
SPAT1317, ,
ICD-O-3
+∞
6.3
6
*
N03AX09, ,
ATC
lamotrigine; oral
+∞
6.3
6
*
SPAT1281, ,
ICD-O-3
+∞
6.3
6
*
EB1CA, ,
ICD-O-3
+∞
6.3
6
*
R01AD05, ,
ATC
budesonide; nasal
+∞
6.3
6
*
-50, ,
ICD-O-3
+∞
6.3
6
*
J209, ,
ICD-10 Finland
Acute bronchitis, unspecified
+∞
6.3
6
*
SPAT1230, ,
ICD-O-3
+∞
6.3
6
*
E118, ,
ICD-O-3
+∞
6.3
6
*
A10BK03, ,
ATC
empagliflozin; oral
+∞
6.3
6
*
R42, ,
ICD-10 Finland
Dizziness and giddiness
+∞
6.3
6
*
F03, ,
ICD-O-3
+∞
6.3
6
*
S97, ,
ICD-O-3
+∞
6.3
6
*
C09AA02, ,
ATC
enalapril; systemic
+∞
6.3
6
*
-31, ,
ICD-O-3
+∞
6.3
6
*
G03GA01, ,
ATC
chorionic gonadotrophin; parenteral
+∞
6.3
6
*
L28, ,
ICD-O-3
+∞
6.3
6
*
M239, ,
ICD-O-3
+∞
6.3
6
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
6.3
6
*
M544, ,
ICD-10 Finland
Lumbago with sciatica
+∞
6.3
6
*
K0531, ,
ICD-O-3
+∞
6.3
6
*
N06AB03, ,
ATC
fluoxetine; oral
+∞
6.3
6
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
6.3
6
*
E118, ,
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
+∞
6.3
6
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
6.3
6
*
R01AD01, ,
ATC
beclometasone; nasal
+∞
6.3
6
*
J01AA04, ,
ATC
lymecycline; systemic
+∞
6.3
6
*
IEY05, ,
ICD-O-3
+∞
6.3
6
*
Z039, ,
ICD-O-3
+∞
6.3
6
*
ND2AA, ,
ICD-O-3
+∞
6.3
6
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
6.3
6
*
F900, ,
ICD-10 Finland
Disturbance of activity and attention
+∞
6.3
6
*
SPAT1308, ,
ICD-O-3
+∞
6.3
6
*
SPAT1212, ,
ICD-O-3
+∞
6.3
6
*
R568, ,
ICD-10 Finland
Other and unspecified convulsions
+∞
6.3
6
*
SDA05, ,
ICD-O-3
+∞
6.3
6
*
P02, ,
ICD-O-3
+∞
6.3
6
*
SPAT1307, ,
ICD-O-3
+∞
6.3
6
*
SJD00, ,
ICD-O-3
+∞
6.3
6
*
K0518, ,
ICD-O-3
+∞
6.3
6
*
H660, ,
ICD-O-3
+∞
6.3
6
*
XKD00, ,
ICD-O-3
+∞
6.3
6
*
N07BB01, ,
ATC
disulfiram; oral
+∞
6.3
6
*
K044, ,
ICD-O-3
+∞
6.3
6
*
S934, ,
ICD-O-3
+∞
6.3
6
*
TQW40, ,
ICD-O-3
+∞
6.3
6
*
EB1MA, ,
ICD-O-3
+∞
6.3
6
*
S800, ,
ICD-10 Finland
Contusion of knee
+∞
6.3
6
*
I872, ,
ICD-O-3
+∞
6.3
6
*
FN1AC, ,
ICD-O-3
+∞
6.3
6
*
R600, ,
ICD-O-3
+∞
6.3
6
*
Z033, ,
ICD-10 Finland
Observation for suspected nervous system disorder
+∞
6.3
6
*
A02BC04, ,
ATC
rabeprazole; oral
+∞
6.3
6
*
J01MA14, ,
ATC
moxifloxacin; systemic
+∞
6.3
6
*
Z023, ,
ICD-O-3
+∞
6.3
6
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
6.3
6
*
IAA01, ,
ICD-O-3
+∞
6.3
6
*
WZA00, ,
ICD-O-3
+∞
6.3
6
*
J01FA15, ,
ATC
telithromycin; oral
+∞
6.3
6
*
F3210, ,
ICD-O-3
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
9
20.16
10.35
1.0
1.0
—
—
—
0
0
8
6
14.62
5.20
1.4
1.2
—
—
—
0
0
18
60
3.59
4.76
1.4
1.7
—
—
—
0
0
58
388
2.86
4.20
4.1
2.9
13.56
14.89
pmol/l
5.72
58
367
24
111
2.67
3.59
2.0
2.2
0.40
0.64
ug/l
2.27
19
46
24
117
2.51
3.20
1.4
2.9
0.81
0.82
mg/l
0.01
17
84
30
171
2.22
2.78
3.2
7.8
—
—
—
0
0
5
9
5.84
2.24
1.2
1.0
—
—
—
0
0
69
577
2.55
2.08
4.2
3.4
1.16
1.28
mmol/l
1.88
69
546
22
123
2.09
2.07
1.5
1.6
86.14
101.60
pmol/l
0.86
14
63
5
13
4.03
1.74
1.4
2.8
42.40
95.21
ug/l
—
5
13
22
132
1.92
1.69
2.4
3.8
7.37
7.41
ph
—
6
19
74
665
2.78
1.69
10.3
8.8
—
—
—
0
0
14
71
2.18
1.66
1.9
2.2
—
—
—
0
0
40
293
1.74
1.60
6.0
9.3
0.00
0.00
e9/l
-0.00
34
233
22
136
1.86
1.54
1.3
1.8
—
—
—
0
0
7
29
2.55
1.43
4.6
3.5
—
—
—
0
0
16
92
1.93
1.38
1.2
1.7
—
—
—
0
0
11
55
2.16
1.35
1.5
1.3
20.07
20.10
nmol/l
0.00
11
48
42
323
1.64
1.33
3.7
3.6
—
—
—
0
0
5
18
2.89
1.30
1.0
1.7
132.98
232.58
pmol/l
—
5
18
21
137
1.73
1.22
1.4
1.7
—
—
—
0
0
28
198
1.64
1.21
1.9
2.2
—
—
—
0
0
17
105
1.79
1.18
2.0
2.5
—
—
—
0
0
70
631
1.96
1.14
10.4
10.6
15.89
24.13
mg/l
2.44
51
464
5
22
2.36
1.05
1.4
1.2
—
—
—
0
0
39
308
1.53
1.03
4.6
7.4
—
—
—
0
0
7
129
0.50
0.99
1.1
1.3
—
—
—
0
0
10
55
1.94
0.97
1.2
2.9
2.44
2.38
mmol/l
—
10
48
6
28
2.23
0.94
1.0
1.3
—
—
—
0
0
6
29
2.15
0.91
1.0
1.2
—
—
—
0
0
10
58
1.83
0.84
1.4
1.8
—
—
—
0
0
9
55
1.72
0.77
2.6
3.2
—
—
—
0
0
11
68
1.72
0.76
1.0
1.2
—
—
—
0
0
10
60
1.76
0.76
4.0
2.2
—
—
—
0
0
5
24
2.15
0.76
2.0
1.1
—
—
—
0
0
5
24
2.15
0.76
2.0
1.5
—
—
—
0
0
7
41
1.77
0.72
1.1
4.2
—
0.30
—
0
10
7
41
1.77
0.72
1.0
1.1
—
—
—
0
0
11
164
0.62
0.71
1.3
1.3
—
—
—
0
0
34
277
1.40
0.70
3.7
7.2
10.85
16.07
umol/l
1.88
34
267
19
249
0.69
0.67
4.1
2.2
—
—
—
0
0
19
142
1.45
0.62
1.9
2.7
—
—
—
0
0
11
74
1.57
0.57
2.0
2.1
—
—
—
0
0
12
86
1.47
0.48
3.0
2.0
—
—
—
0
0
12
86
1.47
0.48
3.3
2.0
—
—
—
0
0
12
86
1.47
0.48
3.5
2.0
—
—
—
0
0
11
78
1.48
0.46
3.2
2.0
—
—
—
0
0
8
59
1.40
0.42
3.0
9.3
5.90
7.36
mmol/l
—
8
59
39
344
1.26
0.42
3.3
2.9
—
—
—
0
0
0
16
0.00
0.41
0.0
6.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.1
—
—
—
0
0
21
173
1.29
0.38
2.2
3.2
248.45
103.68
e6/l
0.23
14
125
17
138
1.30
0.34
2.0
2.7
0.01
0.23
e6/l
—
10
104
19
157
1.28
0.33
2.0
2.6
11.45
11.52
e6/l
0.00
12
122
11
140
0.75
0.31
1.5
1.6
—
—
—
0
0
11
85
1.34
0.30
3.2
1.6
—
—
—
0
0
5
71
0.68
0.27
1.2
1.2
—
—
—
0
0
9
71
1.30
0.27
1.6
2.4
—
—
—
0
0
5
38
1.34
0.24
1.8
2.2
—
—
—
0
0
16
136
1.22
0.22
1.4
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.2
—
33.15
—
0
11
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
22
195
1.18
0.20
23.4
8.2
1.24
1.18
inr
—
7
58
11
132
0.81
0.20
4.4
5.0
—
—
—
0
0
20
176
1.18
0.20
3.7
2.8
9.41
24.53
ng/l
1.71
11
95
19
169
1.16
0.16
1.3
1.5
—
—
—
0
0
6
78
0.75
0.16
4.3
3.7
6.00
9.31
umol/l
—
6
64
5
46
1.09
0.10
1.2
1.2
—
—
—
0
0
11
98
1.14
0.08
1.5
2.0
559.00
569.15
mosm/kgh2o
0.03
11
85
9
101
0.88
0.07
1.6
1.9
1.13
1.81
e6/l
—
9
92
17
158
1.10
0.06
1.2
1.6
2.07
2.33
g/l
—
9
95
10
92
1.10
0.03
1.3
1.3
—
—
—
0
0
15
142
1.07
0.02
1.8
2.6
—
—
—
0
0
12
113
1.07
0.02
3.3
2.9
—
—
—
0
0
12
116
1.04
0.00
3.3
2.7
—
1.02
—
0
12
0
9
0.00
0.00
0.0
6.0
—
36.47
—
0
9
0
9
0.00
0.00
0.0
2.7
—
446.67
—
0
9
0
9
0.00
0.00
0.0
4.6
—
—
—
0
0
6
67
0.89
0.00
3.0
7.3
2.07
1.72
mmol/l
—
6
54
6
64
0.93
0.00
6.3
12.0
106.00
104.63
mmol/l
—
6
64
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
324.01
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
9.20
—
0
5
6
66
0.90
-0.00
3.0
7.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.3
—
71.29
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.72
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
7.27
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.33
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
5
58
0.85
-0.00
5.6
10.8
26.80
25.40
mmol/l
—
5
58
5
58
0.85
-0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.8
—
7.20
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
31.68
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
0.15
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
4.08
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
5.38
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
106.60
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
263.75
—
0
8
0
6
0.00
-0.00
0.0
6.7
—
29.50
—
0
6
0
7
0.00
-0.00
0.0
2.3
—
1.64
—
0
7

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_KLINEFELTER_SYNDROME – Klinefelter syndrome, karyotype 47 XXY

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).