male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly males |
244368 |
2. Check conditionsNone |
244368 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2244 |
4. Check minimum number of eventsNone |
2244 |
5. Include endpointsNone |
2244 |
6. Filter based on genotype QC (FinnGen only) |
1933 |
Control definitions (FinnGen only)
- Control exclude
- N14_MALEGEN
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N40-N51
- Name in latin
- Infertilitas masculina
Male infertility
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18987 | - | 18987 |
| Only index persons | 18715 | - | 18715 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.53 | - | 0.53 |
| Only index persons | 0.71 | - | 0.71 |
| Median age at first event (years) | |||
| Whole population | - | - | 33.28 |
| Only index persons | - | - | 33.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1933 | - | 1933 |
| Unadjusted period prevalence (%) | 0.89 | - | 0.89 |
| Median age at first event (years) | 33.88 | - | 33.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2091
- Matched controls
- 20910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N46
ICD-10 Finland
Male infertility
5016.2
307.7
1894
40
Z31.4
ICD-10 Finland
Procreative investigation and testing
9.0
307.7
565
827
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
10.8
185.2
209
213
L02BG04
ATC
letrozole; oral
32.5
162.0
105
34
60699
ICD-8 Finland
Sterility, male
+∞
117.8
112
*
KGH10
NOMESCO Finland
Operation for phimosis
55.2
103.8
59
11
G03GA01
ATC
chorionic gonadotrophin; parenteral
20.4
89.9
69
35
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
12.7
83.3
82
67
KFB00
NOMESCO Finland
Biopsy of testis
144.0
78.6
83
6
Z31.6
ICD-10 Finland
General counselling and advice on procreation
7.0
72.1
113
170
W15
ICPC
Infertility/subfertility female
20.1
68.8
53
27
121
Kela drug reimbursment
Severe hypofunction of sexual glands
8.6
59.0
76
91
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.1
55.1
251
875
KFB01
NOMESCO Finland
Microscope-assisted testicular biopsy for assisted reproduction treatments
+∞
46.0
44
*
N43.3
ICD-10 Finland
Hydrocele, unspecified
13.5
43.4
41
31
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
6.8
41.7
66
100
6060A
ICD-9 Finland
Infertility, male, Azoospermia
+∞
39.7
38
*
TKF00
NOMESCO Finland
Needle biopsy of testis
363.4
36.1
36
*
60500
ICD-8 Finland
Redundant prepuce and phimosis, Phimosis
+∞
33.4
32
*
N40
ICD-10 Finland
Hyperplasia of prostate
2.6
32.9
210
869
L02BA01
ATC
tamoxifen; oral
12.6
31.5
31
25
XKD00
NOMESCO Finland
Uroflowmetry
2.8
31.2
165
620
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
29.9
658
4305
KFC00
NOMESCO Finland
Unilateral orchiectomy
5.8
29.0
53
93
E29.1
ICD-10 Finland
Testicular hypofunction
3.3
27.1
105
330
N97.4
ICD-10 Finland
Female infertility associated with male factors
94.6
25.7
28
*
KFH30
NOMESCO Finland
Vasovasostomy
136.7
25.7
27
*
N43.4
ICD-10 Finland
Spermatocele
6.5
24.4
40
63
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
34.9
24.3
31
9
Z31.5
ICD-10 Finland
Genetic counselling
3.0
24.1
110
381
G03GA05
ATC
follitropin alfa; parenteral
+∞
24.0
23
*
6050A
ICD-9 Finland
Redundant prepuce and phimosis[PHIMOSIS]
+∞
23.0
22
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.2
22.9
47
92
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
3.4
22.0
79
237
UKC02
NOMESCO Finland
Cystoscopy
2.4
21.8
156
678
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.5
20.6
138
582
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
4.7
20.6
48
105
N44
ICD-10 Finland
Torsion of testis
106.1
19.6
21
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
18.6
551
3815
127
Kela drug reimbursment
Transplant complication
3.8
18.6
57
154
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
18.1
52
134
6069X
ICD-9 Finland
Infertility, male, Male infertility, unspecified
+∞
17.7
17
*
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
3.0
17.6
80
277
XJH00
NOMESCO Finland
Transanal ultrasonography
4.2
17.5
46
111
KFD20
NOMESCO Finland
Excision of hydrocele of testis
63.9
16.7
19
*
L04AA01
ATC
[U] ciclosporin
5.8
16.7
30
52
SPAT1308
SPAT
Sexual health counselling
3.0
16.0
73
253
A55
ICPC
General and Unspecified, Local injection/infiltration
3.5
15.7
54
158
6061A
ICD-9 Finland
Infertility, male, Oligospermia
+∞
15.6
15
*
L04AA06
ATC
mycophenolic acid; systemic
3.3
15.5
59
184
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.1
15.5
144
699
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
15.3
528
3760
7542
FHL
Circumcisio
28.8
15.2
20
7
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
17.9
15.1
23
13
SPAT1312
SPAT
General health counselling
1.6
15.1
451
3106
Q98.0
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
16.6
14.8
23
14
6068A
ICD-9 Finland
Infertility, male, Infertility due to extratesticular causes
+∞
14.6
14
*
N97.9
ICD-10 Finland
Female infertility, unspecified
14.3
14.5
24
17
G04CA01
ATC
alfuzosin; oral
1.9
14.4
202
1134
G04CA02
ATC
tamsulosin; oral
1.7
14.3
294
1844
KED22
NOMESCO Finland
Transurethral resection of prostate
19.3
14.2
21
11
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.4
14.1
23
36
Z94.0
ICD-10 Finland
Kidney transplant status
3.8
13.7
41
109
Z00.0
ICD-10 Finland
General medical examination
1.6
13.6
318
2063
7527
FHL
Vasoepididymostomy
+∞
13.6
13
*
XKC03
NOMESCO Finland
Water cystometry
5.6
13.4
25
45
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.1
13.0
35
86
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.1
12.9
*
383
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
5.1
12.7
26
51
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
12.7
94
416
Z3232
NOMESCO Finland
Midwife
32.2
12.6
16
5
N02BE01
ATC
paracetamol; systemic, rectal
1.5
12.6
1601
14392
M01AC06
ATC
meloxicam; systemic, rectal
1.5
12.5
486
3527
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.1
12.3
*
396
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.3
12.2
31
73
-, ,
ICD-10 Finland
3.4
12.1
42
124
SPAT1197
SPAT
Extensive health check-up of expecting family
2.4
12.0
83
356
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.7
11.9
27
58
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
3.9
11.8
34
88
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.2
11.5
45
143
Z31.2
ICD-10 Finland
In vitrofertilization
11.2
11.5
21
19
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.2
11.3
30
73
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
4.2
11.3
29
69
KFD30
NOMESCO Finland
Operation for spermatocele
35.2
11.3
14
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.4
11.3
44
1190
P72
ICPC
Schizophrenia
0.1
11.0
*
360
J01EA01
ATC
trimethoprim; systemic
2.3
10.9
79
346
RD211, ,
NOMESCO Finland
2.6
10.9
62
243
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.2
10.8
28
67
J01AA02
ATC
doxycycline; systemic
1.4
10.8
1269
11072
H02AB09
ATC
hydrocortisone; systemic
3.0
10.7
47
160
WZC30
NOMESCO Finland
Teaching
1.7
10.7
227
1431
SPAT1153
SPAT
Removal of sutures
1.5
10.5
379
2698
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
10.5
237
1519
N43.0
ICD-10 Finland
Encysted hydrocele
110.6
10.4
11
*
7525
FHL
Detection of vas deferens for exploration (possibly vasotomy or vasography)
+∞
10.4
10
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.0
10.4
*
289
N05AH02
ATC
clozapine; systemic
0.1
10.3
6
415
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
10.3
1156
9981
R50.9
ICD-10 Finland
Fever, unspecified
1.6
10.3
263
1738
Q98.4
ICD-10 Finland
Klinefelter syndrome, unspecified
18.9
10.3
15
8
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
10.0
393
2847
L04AD02
ATC
tacrolimus; systemic
3.1
9.9
40
130
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
3.7
9.9
30
81
J02AC01
ATC
fluconazole; systemic
1.6
9.8
277
1872
N18.8
ICD-10 Finland
Other chronic renal failure
3.3
9.7
35
106
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.3
9.7
22
789
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.6
391
2848
JONO, ,
NOMESCO Finland
3.4
9.6
34
102
M03BX02
ATC
tizanidine; oral
1.3
9.6
1158
10060
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
9.5
133
745
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
7.2
9.5
22
31
KFD96
NOMESCO Finland
Other excision or ligature of scrotal organs
100.5
9.4
10
*
6030A
ICD-9 Finland
Hydrocele, Encysted hydrocele
+∞
9.4
9
*
N48.1
ICD-10 Finland
Balanoposthitis
2.3
9.2
70
314
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
9.2
387
2835
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
9.1
662
5322
I86.1
ICD-10 Finland
Scrotal varices
2.6
9.0
50
194
A98
ICPC
Health maint/preventive medicine
2.0
8.9
2009
19330
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.3
8.9
32
97
JN4BD
NOMESCO Finland
Extensive body CT
1.8
8.8
120
667
A02BC02
ATC
pantoprazole; systemic
1.3
8.8
1031
8868
UJF32
NOMESCO Finland
Coloscopy
1.5
8.8
293
2048
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
8.8
78
373
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
8.7
150
894
SPAT1195
SPAT
Antenatal classes
2.1
8.7
81
395
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.7
270
1861
KFA00
NOMESCO Finland
Exploration of testis
14.1
8.7
14
10
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
8.6
479
3687
N05AH03
ATC
olanzapine; systemic
0.4
8.5
50
1135
D19
ICPC
Teeth/gum symptom/complaint
1.4
8.5
547
4305
7526
FHL
Vasovasostomy
90.4
8.4
9
*
7503
FHL
Hydrosel or funicular surgery
12.8
8.4
14
11
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
8.3
41
150
Y28
ICPC
Limited function/disability (Y)
3.6
8.3
26
72
45610
ICD-8 Finland
Varicose veins of other sites, Of scrotum
10.8
8.3
15
14
L04AD01
ATC
ciclosporin; systemic
2.8
8.3
39
139
N41.1
ICD-10 Finland
Chronic prostatitis
2.4
8.1
54
229
V03AE02
ATC
sevelamer; oral
4.8
8.1
18
38
7505
FHL
Funicular lysis and orchidopexy
3.4
8.1
28
83
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.1
737
6102
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.5
8.0
226
1524
KFH10
NOMESCO Finland
Orchiopexy
22.1
8.0
11
5
A11CC03
ATC
alfacalcidol; systemic
2.7
7.9
40
148
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
13.1
7.9
13
10
N02AX02
ATC
tramadol; systemic, rectal
1.3
7.9
642
5228
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.8
1313
11778
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.8
392
2958
Z49.0
ICD-10 Finland
Preparatory care for dialysis
3.8
7.8
23
61
G03GA06
ATC
follitropin beta; parenteral
45.1
7.7
9
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
7.7
243
1679
TQW80
NOMESCO Finland
Local dermatologic skincare
2.6
7.7
42
162
H02AB06
ATC
prednisolone; systemic
1.3
7.7
676
5559
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
2.7
7.7
39
145
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.5
7.7
26
76
N50.9
ICD-10 Finland
Disorder of male genital organs, unspecified
3.7
7.6
23
62
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
7.6
71
347
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.1
7.6
31
102
Y10
ICPC
Infertility/subfertility male
8.1
7.6
16
20
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
0.2
7.6
8
375
SPAT1360
SPAT
Extensive global examination
2.0
7.5
76
383
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
7.1
7.5
17
24
G03GA02
ATC
human menopausal gonadotrophin; parenteral
80.4
7.4
8
*
KF8KT
NOMESCO Finland
Sclerotherapy of scrotum
80.4
7.4
8
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
7.4
79
406
J01MA06
ATC
norfloxacin; oral
2.0
7.4
80
413
B03XA02
ATC
darbepoetin alfa; parenteral
3.0
7.4
32
109
H02AB04
ATC
methylprednisolone; systemic
1.6
7.4
169
1088
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
7.3
326
2407
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.3
506
4016
KED52
NOMESCO Finland
Visual laser resection of prostate
+∞
7.3
7
*
A02BC03
ATC
lansoprazole; oral
1.4
7.3
316
2322
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.3
191
1269
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
3.2
7.3
27
84
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
7.2
382
2909
SPAT1263
SPAT
Sampling
1.3
7.1
576
4671
N48.4
ICD-10 Finland
Impotence of organic origin
2.2
7.1
60
282
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.2
7.1
55
250
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.0
7.1
30
101
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
2.2
7.1
54
244
G04CB02
ATC
dutasteride; oral
2.4
7.1
47
200
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.9
7.1
86
463
A12AA04
ATC
calcium carbonate; oral
3.0
7.0
29
96
137
Kela drug reimbursment
Uraemia requiring dialysis
3.6
7.0
22
61
R06AE07
ATC
cetirizine; oral
1.3
7.0
709
5927
SPAT1216
SPAT
Assessment of functional ability
1.7
7.0
112
656
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
6.9
103
590
G04CA52
ATC
tamsulosin and dutasteride; systemic
2.0
6.9
67
333
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
6.9
95
532
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
6.9
58
273
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.8
164
1068
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.6
6.8
38
149
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
6.8
75
391
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.1
6.7
62
302
SPAT1301
SPAT
No procedures
1.4
6.7
360
2741
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.7
347
2627
J01MA12
ATC
levofloxacin; systemic
1.5
6.7
207
1425
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.7
6.7
35
133
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.1
6.6
27
89
H01AC01
ATC
somatropin; parenteral
7.8
6.6
14
18
R01AD09
ATC
mometasone; nasal
1.3
6.6
744
6294
M48.0
ICD-10 Finland
Spinal stenosis
1.8
6.6
89
496
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.5
6.6
22
64
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.6
108
638
T28
ICPC
Limited function/disability (T)
3.8
6.5
19
50
SPAT1229
SPAT
Assessment of need for aid
2.2
6.5
50
227
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.5
1406
12865
N48.8
ICD-10 Finland
Other specified disorders of penis
6.2
6.5
16
26
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
7.4
6.4
14
19
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
6.4
79
428
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.4
129
806
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
2.1
6.3
56
269
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
6.0
6.3
16
27
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
6.3
341
2600
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
11.1
6.3
11
10
OAA70, ,
SPAT
3.5
6.3
21
61
Q98.6
ICD-10 Finland
Male with structurally abnormal sex chromosome
+∞
6.3
6
*
60300
ICD-8 Finland
Hydrocele, Tunicae vaginalis testis
+∞
6.3
6
*
60301
ICD-8 Finland
Hydrocele, Funiculi testis
+∞
6.3
6
*
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
0.2
6.2
8
334
SPAT1210
SPAT
Application of cast or individual aid
2.2
6.2
50
232
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.2
313
2361
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
3.3
6.1
22
67
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.4
6.1
39
163
TK800
NOMESCO Finland
Hemodialysis
2.3
6.1
43
188
R03BA01
ATC
beclometasone; inhalant
1.5
6.1
163
1087
SPAT1325
SPAT
Vaccination
1.4
6.1
309
2329
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.1
251
1827
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
0.3
6.1
15
507
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
6.7
6.0
14
21
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
6.0
81
451
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
315
341
10.70
269.45
1.7
1.7
11.68
7.29
iu/l
4.97
220
270
446
835
6.52
236.79
1.9
1.6
6.43
4.38
u/l
8.65
343
686
278
321
9.84
225.66
8.7
6.6
9.86
8.12
%
3.60
278
321
278
321
9.84
225.66
4.3
3.3
34.38
48.71
%
15.78
278
321
794
3838
2.72
99.94
3.5
2.4
15.20
14.99
nmol/l
0.36
753
3639
340
1028
3.76
95.94
1.9
1.5
—
—
—
0
0
93
78
12.43
93.09
1.4
1.3
11.92
10.38
u/l
0.28
80
60
240
650
4.04
78.62
1.9
1.8
244.09
257.10
mu/l
0.40
235
620
316
1364
2.55
45.96
6.3
5.5
—
—
—
0
0
85
158
5.57
43.81
1.9
1.6
529.78
286.67
mu/l
0.41
77
131
313
1490
2.29
36.12
2.7
1.9
219.90
223.25
pmol/l
0.21
301
1439
371
1913
2.14
35.07
2.6
2.0
31.46
34.54
nmol/l
3.13
366
1889
543
3406
1.80
28.20
4.5
2.9
0.00
0.01
estimate
1.23
166
1135
63
152
4.24
23.87
5.1
6.6
6.32
27.50
u/l
1.00
13
24
905
7073
1.49
17.24
3.9
2.7
0.03
6.92
estimate
1.57
178
1241
898
7014
1.49
17.12
3.9
2.7
0.00
0.00
estimate
-0.00
178
1267
748
5634
1.51
16.99
3.7
2.5
0.65
0.00
estimate
0.49
155
1117
905
7107
1.48
16.64
3.9
2.7
6.06
0.27
estimate
0.47
165
1144
960
7672
1.46
15.91
3.7
2.9
1.50
1.35
ug/l
0.56
901
7053
1585
14061
1.53
14.81
3.8
3.7
1.75
1.78
mu/l
0.69
1510
13311
1290
10987
1.45
14.81
3.2
3.1
14.88
14.72
pmol/l
1.55
1217
10308
747
5842
1.43
13.14
3.1
2.5
22.31
21.79
%
0.27
230
1444
230
1396
1.73
12.57
2.7
2.3
358.03
365.02
nmol/l
0.27
215
1314
376
2605
1.54
12.02
4.3
2.4
1.71
2.46
e6/l
3.41
357
2397
449
3252
1.48
11.57
3.6
2.7
1.02
1.02
kg/l
0.19
296
1952
1255
10886
1.38
11.37
4.1
3.7
7.48
7.66
mm/h
0.20
1198
10407
45
149
3.06
10.79
1.9
1.5
0.13
0.13
nmol/l
0.14
35
105
173
1014
1.77
10.67
2.2
2.1
7.93
9.75
ug/l
0.44
156
920
863
7115
1.36
10.42
4.4
2.8
42.36
278.39
e6/l
0.71
11
93
519
3953
1.42
10.06
4.5
2.9
21.83
98.21
e6/l
1.87
433
2993
181
1104
1.70
9.69
2.9
2.5
67.13
77.48
ml/min/173m2
2.09
70
403
223
1438
1.62
9.63
5.9
5.3
217.34
233.07
u/l
2.30
213
1391
535
4142
1.39
9.33
2.8
2.5
360.17
371.78
umol/l
2.36
509
3871
452
3402
1.42
9.28
4.3
2.9
0.20
0.37
e6/l
2.36
363
2437
390
2870
1.44
9.04
3.4
3.2
1435.96
971.24
ng/l
0.49
325
2263
678
5540
1.33
8.17
3.0
2.6
—
—
estimate
—
0
0
567
4516
1.35
8.11
2.4
2.0
0.57
0.59
ug/l
0.26
238
1758
407
3126
1.37
7.24
1.9
2.4
—
—
—
0
0
26
81
3.24
6.98
26.2
18.9
124.37
124.89
ug/l
0.01
19
57
2029
19706
2.00
6.91
21.6
18.0
47.67
45.31
%
0.34
2018
19552
2029
19708
2.00
6.88
21.0
17.5
4.86
4.88
e12/l
1.84
2001
19359
1278
11525
1.28
6.80
9.2
8.0
73.89
76.53
u/l
1.90
1239
11110
2028
19701
1.98
6.77
20.9
17.5
89.66
89.66
fl
0.01
2019
19561
2029
19716
1.98
6.74
21.1
17.6
6.43
6.56
e9/l
2.69
1998
19371
2029
19720
1.97
6.67
21.1
17.6
146.41
147.33
g/l
2.27
2019
19580
2026
19682
1.94
6.66
21.0
17.6
243.12
244.78
e9/l
0.67
1997
19371
255
1834
1.44
6.60
13.8
8.2
1.04
1.02
mmol/l
0.40
243
1758
83
463
1.83
6.13
10.6
6.2
1261.43
806.27
iu/ml
0.31
14
64
69
363
1.93
6.10
5.0
3.0
340.00
1438.11
u/ml
—
5
19
377
2939
1.34
6.02
1.9
2.3
—
—
—
0
0
118
733
1.65
5.97
7.8
5.7
149.56
102.24
ng/l
1.82
107
683
1777
16849
1.36
5.94
15.3
11.9
24.79
24.38
mg/l
0.18
1428
13289
1936
18666
1.50
5.58
17.6
13.9
86.71
82.72
umol/l
3.77
1922
18516
342
2665
1.34
5.45
2.4
2.2
2.89
2.68
mg/l
1.12
310
2354
405
3242
1.31
5.33
2.4
1.9
1.35
0.96
mg/l
0.60
295
2281
137
909
1.54
5.29
3.4
2.1
0.10
0.46
e6/l
2.96
132
869
55
283
1.97
5.23
2.0
1.5
—
—
—
0
0
100
619
1.65
5.17
3.8
4.3
56.52
52.11
%
0.92
100
608
144
975
1.51
5.07
10.0
13.3
94.67
93.76
%
1.69
144
970
1718
16300
1.30
5.02
16.8
13.3
139.68
139.80
mmol/l
1.58
1689
16004
30
123
2.46
4.96
1.7
1.3
—
—
—
0
0
1721
16346
1.30
4.89
13.3
10.9
92.25
94.18
ml/min/173m2
3.61
1583
14903
495
4108
1.27
4.88
1.6
1.5
—
—
—
0
0
708
6124
1.24
4.84
3.3
2.6
167.87
173.76
ug/l
0.28
683
5877
630
5386
1.24
4.79
3.4
2.9
50.49
68.49
ng/l
0.18
400
3097
73
425
1.74
4.75
4.0
4.6
1.13
1.43
mmol/l
3.37
73
415
142
975
1.49
4.70
10.0
13.2
1.37
1.46
%
0.57
142
970
995
8936
1.22
4.66
9.9
11.8
3.90
4.06
e9/l
1.36
891
7850
361
2895
1.30
4.66
2.9
2.5
—
—
—
0
0
188
1366
1.41
4.62
17.4
9.7
9.45
8.32
mmol/l
1.56
182
1320
278
2153
1.34
4.60
3.0
2.6
0.46
0.78
e6/l
2.05
169
1059
1724
16419
1.28
4.51
17.0
13.4
4.02
3.99
mmol/l
2.87
1695
16078
1938
18785
1.43
4.41
11.4
9.8
33.80
35.66
u/l
3.83
1914
18489
137
948
1.48
4.38
10.4
13.5
0.74
0.65
%
1.93
137
942
1778
17022
1.30
4.31
4.2
3.7
1.41
1.47
mmol/l
2.92
1716
16403
47
247
1.92
4.27
3.1
1.9
—
—
—
0
0
512
4327
1.24
4.25
3.3
2.2
0.32
0.05
estimate
0.40
155
1034
269
2100
1.32
4.22
4.1
2.8
15.26
15.06
umol/l
0.15
258
2011
72
435
1.68
4.14
1.8
1.7
149.93
140.60
au/ml
0.20
15
138
1868
18025
1.34
4.13
5.0
4.6
2.88
2.95
mmol/l
3.29
1798
17424
251
1952
1.32
4.04
4.3
2.8
2.32
2.34
g/l
0.27
237
1850
696
6102
1.21
4.01
11.9
8.2
1.20
1.20
mmol/l
1.03
608
5356
681
5958
1.21
4.01
2.8
2.4
72.27
69.09
nmol/l
2.50
644
5640
836
7470
1.20
3.91
7.1
6.8
11.65
12.53
umol/l
1.10
806
7179
287
2285
1.30
3.90
1.7
1.7
40996590.00
19940753.15
pmol/l
0.31
261
2011
1855
17905
1.32
3.90
4.7
4.2
1.29
1.27
mmol/l
1.74
1793
17316
294
2349
1.29
3.89
1.3
1.3
23.24
24.06
iu/ml
0.06
80
662
236
1832
1.32
3.85
4.4
2.8
26.85
25.92
%
0.44
225
1758
61
360
1.72
3.85
2.0
1.5
—
—
—
0
0
38
193
1.99
3.83
2.3
1.6
—
—
—
0
0
623
5428
1.21
3.79
10.6
7.9
1.20
1.20
mmol/l
0.12
591
5129
122
851
1.46
3.78
6.8
4.2
1.23
1.22
mmol/l
0.82
115
775
50
280
1.80
3.77
1.0
1.2
—
45.71
—
0
7
432
3628
1.24
3.76
1.3
1.3
1.33
1.86
u/ml
0.77
165
1108
51
289
1.78
3.71
2.0
1.4
—
—
—
0
0
28
128
2.20
3.70
1.7
1.5
—
—
—
0
0
1857
17954
1.31
3.64
4.8
4.3
4.67
4.75
mmol/l
3.27
1793
17414
27
123
2.21
3.61
1.7
1.6
—
—
—
0
0
28
130
2.17
3.58
1.7
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
65
399
1.65
3.57
4.2
3.6
0.25
0.31
iu/ml
0.84
30
203
124
879
1.44
3.55
2.1
1.7
—
—
—
0
0
27
124
2.19
3.54
1.7
1.6
—
—
—
0
0
27
124
2.19
3.54
1.7
1.6
—
—
—
0
0
262
2090
1.29
3.51
1.3
1.2
12.54
8.08
u/ml
0.50
134
922
106
733
1.47
3.46
1.2
1.2
121.07
139.02
u/ml
0.20
45
255
28
132
2.14
3.46
1.7
1.5
—
—
—
0
0
1632
15577
1.22
3.40
4.3
3.8
5.87
5.90
mmol/l
0.36
1565
14825
460
3928
1.22
3.39
3.9
3.4
2.35
2.35
mmol/l
0.01
437
3674
295
2400
1.27
3.38
5.0
4.2
0.82
0.83
mmol/l
0.72
284
2291
1682
16106
1.23
3.38
5.4
4.8
38.49
38.33
mmol/mol
0.30
1623
15585
17
65
2.63
3.30
2.0
1.9
4.91
1.10
u/field
0.51
11
40
60
369
1.64
3.29
2.9
1.8
—
—
—
0
0
96
659
1.48
3.26
6.0
3.2
1.47
1.29
mg/l
0.93
91
623
5
187
0.27
3.25
2.6
2.4
171.60
140.89
nmol/l
—
5
160
27
131
2.07
3.12
1.1
1.1
1576.70
1466.65
miu/ml
0.27
27
131
6
8
7.52
3.05
2.5
1.8
—
—
—
0
0
85
578
1.49
3.05
1.3
1.2
—
—
—
0
0
16
62
2.59
3.04
2.6
2.0
—
—
—
0
0
20
87
2.31
3.01
1.0
1.1
3.80
6.79
iu/ml
—
8
29
5
5
10.02
2.98
1.0
1.0
—
—
—
0
0
42
245
1.73
2.84
1.1
1.1
3.02
2.42
0.27
11
74
39
223
1.76
2.82
1.4
1.6
—
—
—
0
0
27
137
1.98
2.80
3.6
3.7
10.33
10.72
mmol/l
0.21
27
137
61
394
1.56
2.79
2.9
1.8
—
—
—
0
0
242
1973
1.26
2.74
3.1
3.2
2.42
2.42
mmol/l
0.08
220
1784
523
4602
1.18
2.74
4.4
3.0
63.90
59.27
u/l
0.38
498
4356
14
54
2.60
2.70
3.9
2.9
—
—
—
0
0
14
54
2.60
2.70
4.0
2.9
—
—
—
0
0
14
54
2.60
2.70
4.0
2.9
—
—
—
0
0
14
54
2.60
2.70
4.1
2.9
—
—
—
0
0
479
4190
1.19
2.69
5.4
4.6
11.23
8.32
mg/mmol
0.43
351
2944
137
1042
1.34
2.64
1.4
1.3
379.02
309.82
u/ml
0.18
132
982
18
80
2.26
2.60
2.7
1.5
—
—
—
0
0
106
776
1.39
2.60
1.3
1.3
—
—
—
0
0
38
222
1.72
2.58
2.2
1.4
—
—
—
0
0
6
11
5.47
2.54
13.0
2.1
—
—
—
0
0
68
462
1.49
2.50
1.1
1.1
3.15
3.57
0.31
15
119
558
6229
0.86
2.49
3.2
3.7
35.32
39.82
u/l
0.67
530
5926
21
102
2.07
2.47
3.2
2.1
—
—
—
0
0
21
102
2.07
2.47
3.1
2.1
—
—
—
0
0
21
102
2.07
2.47
3.1
2.1
—
—
—
0
0
25
131
1.92
2.41
3.1
2.1
—
—
—
0
0
195
1576
1.26
2.40
9.3
10.7
0.75
0.86
mmol/l
0.19
163
1321
368
4237
0.84
2.39
1.8
2.1
1.37
1.45
%
1.30
328
3843
52
337
1.56
2.39
1.3
1.3
3.32
3.46
u/ml
0.03
19
129
75
526
1.44
2.37
3.6
2.9
198.63
181.59
%
0.71
75
507
22
111
1.99
2.35
2.5
1.4
—
—
—
0
0
53
347
1.54
2.33
1.5
1.3
—
—
—
0
0
139
1083
1.30
2.30
1.5
1.4
—
—
—
0
0
107
804
1.35
2.27
4.1
3.5
1.55
1.48
%
0.20
107
799
189
1533
1.26
2.27
2.0
1.7
—
—
—
0
0
12
47
2.56
2.27
2.8
1.9
1.61
1.37
ratio
0.36
12
47
27
149
1.82
2.24
3.0
2.0
—
—
—
0
0
61
417
1.48
2.21
1.0
1.1
—
—
—
0
0
11
41
2.69
2.20
4.5
3.4
—
—
—
0
0
11
41
2.69
2.20
4.5
3.4
—
—
—
0
0
11
41
2.69
2.20
4.5
3.4
—
—
—
0
0
61
418
1.47
2.19
1.0
1.1
—
—
—
0
0
6
14
4.29
2.15
25.2
11.1
92.50
212.11
e6/l
—
6
9
34
204
1.68
2.14
2.7
1.6
—
—
—
0
0
167
1345
1.26
2.14
4.8
3.7
28.66
27.57
%
0.77
128
994
62
881
0.69
2.14
2.7
3.2
—
—
—
0
0
385
3369
1.17
2.14
1.4
1.5
2.37
2.55
g/l
1.94
312
2430
17
81
2.11
2.12
2.8
1.5
—
—
—
0
0
15
68
2.21
2.11
7.7
7.1
1.74
7.12
pmol/l
—
5
26
22
116
1.91
2.11
4.4
3.2
16.88
14.41
index
0.15
17
91
76
549
1.40
2.08
1.4
1.3
—
51.64
—
0
7
11
249
0.44
2.07
1.8
3.2
—
—
—
0
0
9
31
2.91
2.07
1.0
1.1
19.62
53.80
iu/ml
—
9
31
18
89
2.03
2.06
2.7
1.5
—
—
—
0
0
30
177
1.71
2.02
1.5
1.4
0.18
0.18
nmol/l
0.05
22
152
181
1483
1.24
2.01
2.0
1.7
—
—
—
0
0
445
3961
1.16
1.98
4.9
4.7
91.31
91.14
%
0.06
435
3894
34
210
1.63
1.95
1.6
1.5
239.38
340.83
pmol/l
1.25
26
184
88
661
1.35
1.92
1.3
1.3
232.97
188.65
miu/ml
0.50
33
269
68
491
1.40
1.89
1.5
1.3
190.48
214.42
pmol/l
0.43
68
491
891
8321
1.12
1.89
6.9
5.6
6.66
6.75
mmol/l
0.61
866
7969
18
93
1.94
1.85
1.8
2.2
20.00
19.88
mg/l
—
6
35
184
1526
1.23
1.85
1.7
1.6
1274.17
1112.87
nmol/l
1.77
145
1219
475
4269
1.15
1.85
2.3
2.3
210.48
364.41
u/l
3.46
464
4087
48
326
1.48
1.84
1.3
1.3
3.56
3.65
u/ml
0.05
27
170
71
522
1.37
1.79
1.5
1.3
272.68
229.28
u/ml
0.61
47
342
62
447
1.40
1.75
4.1
2.4
23.61
24.59
mmol/l
1.51
62
439
5
13
3.85
1.71
2.4
3.3
—
—
—
0
0
76
1000
0.75
1.69
2.7
3.2
—
—
—
0
0
109
862
1.28
1.68
1.7
2.8
67.29
67.42
g/l
0.06
101
832
93
722
1.30
1.65
5.1
2.8
1.31
1.52
mmol/l
0.25
69
540
1678
16327
1.14
1.63
16.3
14.6
337.07
337.01
g/l
0.09
1665
16244
237
2043
1.18
1.60
2.4
1.8
—
—
—
0
0
17
91
1.88
1.60
4.8
3.3
0.59
0.93
index
1.59
17
91
44
304
1.46
1.59
1.7
1.3
—
—
—
0
0
22
130
1.70
1.53
2.9
2.0
—
—
—
0
0
78
600
1.31
1.50
1.3
1.4
—
—
—
0
0
20
116
1.73
1.48
8.2
3.9
—
—
—
0
0
7
28
2.50
1.45
15.4
5.5
5.16
6.32
mmol/l
—
7
28
50
361
1.39
1.45
1.6
1.5
—
—
—
0
0
5
16
3.13
1.44
2.0
1.4
214.80
326.12
umol/24h
—
5
16
634
5885
1.11
1.43
11.3
10.0
1.20
1.16
inr
1.08
537
4875
69
527
1.32
1.41
1.7
1.8
1.28
1.47
g/l
1.19
61
463
10
46
2.18
1.40
1.2
1.3
—
—
—
0
0
7
29
2.42
1.39
1.0
1.0
—
—
—
0
0
264
2325
1.16
1.39
3.3
3.4
128.97
155.72
ug/g
0.89
221
2019
639
5948
1.11
1.36
7.7
5.9
37.70
37.67
g/l
0.05
618
5644
47
341
1.39
1.34
1.1
1.1
117.28
112.90
%
0.39
47
319
48
350
1.38
1.33
1.1
1.1
—
—
—
0
0
37
258
1.44
1.31
2.6
2.8
1.81
1.59
mmol/l
0.48
37
252
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
5
18
2.78
1.28
1.2
1.1
—
—
—
0
0
41
294
1.40
1.26
1.4
1.3
18.50
29.14
u/l
0.43
35
257
127
1062
1.21
1.25
1.3
1.3
11.22
51.36
au/ml
—
8
68
6
25
2.40
1.24
1.8
2.4
—
—
—
0
0
27
179
1.52
1.23
1.1
1.1
28.56
18.52
u/ml
0.82
12
84
9
45
2.00
1.23
5.0
5.2
3.89
4.60
ug/l
—
9
45
109
900
1.22
1.22
1.0
1.1
—
—
—
0
0
8
37
2.17
1.21
1.0
1.5
—
64.00
—
0
5
1529
14883
1.10
1.19
16.0
14.9
13.32
13.25
%
1.89
1514
14690
228
2014
1.15
1.17
3.3
2.6
0.43
0.51
e6/l
0.24
118
908
21
133
1.58
1.17
1.0
1.1
—
1.45
—
0
5
31
215
1.45
1.16
5.3
4.8
216.82
166.24
u/ml
0.12
31
197
121
1433
0.83
1.15
1.9
2.2
0.29
0.33
mg/l
0.46
65
830
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
25
167
1.50
1.12
1.8
1.7
—
—
—
0
0
7
30
2.34
1.12
1.1
1.3
122.71
94.50
%
—
7
30
42
310
1.36
1.12
4.3
2.2
16.72
18.10
%
1.56
42
303
19
119
1.60
1.11
1.6
1.4
60999.00
68188.32
e6/l
0.05
13
85
19
119
1.60
1.11
3.2
3.1
1746.32
1616.74
mg
0.06
19
119
7
31
2.26
1.10
1.0
1.1
—
—
—
0
0
47
356
1.33
1.07
1.6
1.5
288.10
265.84
ug/g
0.26
28
201
163
1416
1.16
1.07
8.0
4.4
1.56
1.79
mmol/l
0.43
141
1259
43
322
1.34
1.06
1.8
1.6
18992.58
17016.30
e6/l
0.13
31
235
131
1120
1.18
1.05
2.3
2.3
29.96
14.45
au/ml
1.38
22
164
6
125
0.48
1.04
2.7
2.2
—
—
—
0
0
41
306
1.35
1.04
6.4
2.4
9.06
8.51
kpa
1.29
41
298
14
83
1.69
1.01
1.0
1.2
—
0.06
—
0
5
247
2741
0.89
1.00
3.6
3.5
559.44
607.28
ng/l
0.09
165
1939
9
48
1.88
1.00
4.0
2.4
153.76
101.88
ng/l
—
9
48
12
201
0.59
1.00
6.7
13.6
0.52
0.57
mmol/l
0.38
12
184
36
265
1.36
1.00
1.1
1.1
103.06
104.07
%
0.07
36
254
20
131
1.53
1.00
1.9
2.1
34.20
33.12
pg
0.79
20
131
22
149
1.48
0.95
1.9
1.4
283.00
284.66
mosm/kgh2o
0.11
17
115
53
419
1.27
0.92
2.8
1.8
—
—
—
0
0
15
94
1.60
0.90
1.1
1.2
102.67
108.28
pmol/l
0.13
15
94
554
5220
1.08
0.88
1.8
1.8
97.48
96.75
pmol/l
0.14
334
2959
8
43
1.86
0.87
1.0
1.0
—
—
—
0
0
314
2887
1.10
0.87
1.7
1.6
17.73
17.86
nmol/l
0.07
281
2589
13
204
0.63
0.86
1.0
1.1
272.31
265.17
mg/l
0.17
13
191
8
45
1.78
0.84
1.5
1.1
—
—
—
0
0
15
98
1.53
0.78
1.7
1.6
16.88
8.68
ug/l
0.36
15
91
13
82
1.59
0.78
1.1
1.1
—
—
—
0
0
16
107
1.50
0.76
1.3
1.1
9.94
5.74
mm/h
0.50
16
107
31
235
1.32
0.76
2.4
1.9
1.40
1.77
mmol/l
2.22
31
228
19
133
1.43
0.73
1.6
1.6
67.00
54.71
%
0.63
12
96
97
839
1.16
0.73
6.1
5.5
78.10
17.61
ug/l
0.60
83
690
37
291
1.28
0.71
4.5
2.0
127.03
142.44
g/l
2.47
32
226
65
545
1.20
0.71
1.2
1.1
3.38
2.74
u/ml
0.15
31
294
43
346
1.25
0.69
1.2
1.1
26.60
95.98
iu/ml
—
10
85
42
337
1.25
0.69
1.2
1.1
10.36
14.18
au/ml
0.44
17
137
9
59
1.53
0.68
1.0
1.1
—
—
—
0
0
51
421
1.22
0.66
2.7
2.6
—
—
—
0
0
49
403
1.22
0.66
1.8
1.5
33.73
17.27
e6/l
0.33
37
295
552
5266
1.07
0.63
4.5
3.8
9.70
9.69
mmol/l
0.01
505
4732
44
361
1.22
0.61
2.7
2.4
315.85
167.66
ug/min
0.45
35
236
13
187
0.69
0.61
1.8
1.6
12.48
13.07
umol/l
0.24
13
181
18
244
0.74
0.60
1.2
1.1
—
—
—
0
0
18
243
0.74
0.59
1.2
1.6
—
—
—
0
0
65
557
1.17
0.58
1.3
1.5
3.69
5.87
iu/ml
0.81
22
140
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
30
237
1.27
0.58
1.1
1.1
—
—
—
0
0
39
474
0.82
0.57
1.3
1.5
—
—
—
0
0
6
36
1.67
0.56
1.3
1.5
2.22
2.00
mg/l
—
6
29
1507
14826
1.06
0.56
3.1
3.4
45.09
50.37
u/l
2.33
1455
14396
21
274
0.76
0.56
4.5
2.5
28.19
28.48
mg/l
0.01
16
195
17
124
1.37
0.55
4.9
4.0
63.88
60.05
%
0.40
17
108
6
37
1.62
0.55
1.2
1.5
42.33
42.18
g/l
—
6
37
49
413
1.19
0.54
1.9
1.5
5662.68
901.28
e6/l
0.53
41
323
44
367
1.20
0.54
1.1
1.1
0.62
0.95
u/ml
0.20
14
122
12
82
1.47
0.54
2.9
1.3
181.33
185.52
mmol/24h
0.08
12
82
15
108
1.39
0.53
1.1
1.1
—
—
—
0
0
77
676
1.14
0.52
2.8
4.0
4.64
4.82
pmol/l
1.04
71
625
18
237
0.76
0.52
1.3
2.0
—
—
—
0
0
52
444
1.18
0.51
1.6
1.4
1193.21
528.05
mg/l
0.48
52
425
6
41
1.46
0.50
1.0
1.1
—
—
—
0
0
6
41
1.46
0.50
1.2
1.2
—
—
—
0
0
12
84
1.43
0.49
1.9
1.8
—
—
—
0
0
71
806
0.88
0.49
4.3
3.0
143.65
141.42
ng/l
0.02
62
690
152
1399
1.09
0.47
2.5
2.6
0.23
0.24
g/l
0.23
143
1301
18
137
1.32
0.47
1.8
1.9
12.56
19.02
ug/l
2.92
18
132
46
392
1.18
0.47
1.5
1.3
3.80
3.72
mmol/l
0.24
46
370
7
48
1.46
0.46
1.4
1.9
—
—
—
0
0
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
8
118
0.68
0.45
1.3
1.1
—
—
—
0
0
14
187
0.75
0.45
1.3
1.3
—
—
—
0
0
49
422
1.17
0.45
1.1
1.1
0.86
4.74
u/ml
4.89
22
233
57
497
1.15
0.45
1.1
1.1
8.98
8.23
u/ml
0.08
35
293
5
32
1.56
0.42
2.4
2.2
—
—
—
0
0
22
272
0.81
0.41
2.2
3.5
1.46
2.04
ratio
0.54
14
143
5
33
1.52
0.41
1.4
1.3
128.40
128.18
nmol/24h
—
5
33
0
15
0.00
0.41
0.0
1.3
—
1.77
—
0
9
81
730
1.11
0.40
1.7
1.6
0.01
0.25
iu/ml
—
8
127
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
2.2
—
8.55
—
0
8
167
1559
1.08
0.39
1.1
1.1
0.79
0.73
ratio
0.29
12
121
13
97
1.34
0.39
1.5
1.2
—
—
—
0
0
54
475
1.14
0.39
1.1
1.1
0.63
1.77
u/ml
1.38
23
226
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
5
37
1.35
0.37
2.6
2.2
21.00
21.70
mg/l
—
5
32
172
1829
0.94
0.35
3.6
3.0
7.84
8.53
umol/l
0.20
161
1623
5
79
0.63
0.35
1.2
1.5
560.40
426.38
u/l
—
5
73
29
341
0.85
0.35
2.0
2.2
9.95
10.45
g/l
0.30
24
319
19
154
1.24
0.34
4.3
3.8
8.14
9.27
mg/l
0.32
13
124
18
145
1.24
0.33
1.1
1.1
—
—
—
0
0
14
109
1.29
0.33
2.5
2.0
—
—
—
0
0
6
46
1.31
0.33
1.3
1.8
7.88
8.47
ug/l
—
6
46
152
1427
1.07
0.33
3.1
2.5
10.18
10.78
g/l
1.17
143
1326
25
296
0.84
0.33
2.2
3.7
46.25
47.08
mg/l
0.02
19
246
164
1544
1.07
0.33
4.0
3.1
34.25
75.77
u/l
0.79
151
1381
77
703
1.10
0.32
1.6
1.8
6.98
3.86
mg/l
0.68
54
496
17
137
1.24
0.32
1.2
1.1
—
—
—
0
0
29
337
0.86
0.31
2.0
2.3
0.99
0.71
g/l
0.18
24
311
7
52
1.35
0.31
1.0
1.1
—
—
—
0
0
25
294
0.85
0.31
2.2
3.7
42.63
37.14
mg/l
0.20
18
244
7
99
0.71
0.30
1.4
1.4
—
72.83
%
—
0
12
7
99
0.71
0.30
1.1
1.1
—
—
—
0
0
17
138
1.23
0.30
3.9
2.8
—
102.31
—
0
20
7
54
1.30
0.30
7.4
3.9
1.08
1.53
ratio
—
7
49
45
400
1.13
0.30
1.1
1.1
3.07
4.14
u/ml
0.36
18
199
62
563
1.10
0.29
1.7
1.8
9.35
13.84
u/ml
0.77
18
212
32
279
1.15
0.28
2.0
1.6
—
—
—
0
0
8
62
1.29
0.28
1.1
1.1
—
—
—
0
0
8
63
1.27
0.27
1.5
1.1
—
—
—
0
0
30
261
1.15
0.27
1.4
1.2
—
—
—
0
0
30
261
1.15
0.27
1.4
1.2
—
—
—
0
0
10
128
0.78
0.26
1.3
1.2
45.60
67.01
u/l
—
10
110
75
693
1.09
0.26
1.6
1.6
—
—
—
0
0
18
214
0.84
0.26
1.1
1.2
—
—
—
0
0
5
74
0.67
0.26
1.8
1.6
5.80
5.28
u/l
—
5
61
10
126
0.79
0.24
2.3
1.7
—
—
—
0
0
382
3714
1.03
0.23
1.9
1.9
3.91
4.04
ratio
1.09
309
2830
53
486
1.09
0.23
1.1
1.1
0.60
2.77
u/ml
3.26
25
252
14
116
1.21
0.22
1.2
1.3
0.59
3.79
u/ml
—
9
64
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
8
103
0.78
0.21
1.4
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
9
112
0.80
0.20
2.3
2.3
947.00
701.88
ml
—
9
78
6
49
1.23
0.20
1.8
1.5
—
—
—
0
0
6
49
1.23
0.20
1.8
1.5
—
—
—
0
0
6
49
1.23
0.20
9.7
3.2
—
—
—
0
0
34
375
0.91
0.19
2.6
1.7
—
—
—
0
0
290
2820
1.03
0.19
1.6
1.6
3.64
3.70
mmol/l
0.36
209
1867
35
318
1.10
0.19
1.8
1.6
—
—
—
0
0
6
53
1.13
0.18
1.0
1.2
—
—
—
0
0
13
109
1.19
0.18
2.1
2.3
24.50
28.43
mg/l
—
6
80
15
128
1.17
0.18
1.7
1.3
91.20
88.15
umol/l
0.11
15
128
7
59
1.19
0.18
4.1
4.0
2.29
1.20
%
—
7
59
25
224
1.12
0.17
1.1
1.1
—
—
—
0
0
45
485
0.93
0.17
1.1
1.1
2.79
3.71
eliau/ml
—
7
81
12
101
1.19
0.16
1.4
2.0
176.50
182.70
u/l
0.28
12
101
731
7214
1.02
0.16
1.8
1.8
1.49
1.61
mmol/l
3.29
661
6489
29
318
0.91
0.15
1.2
1.0
3.28
2.48
eliau/ml
0.26
18
181
10
118
0.85
0.14
2.0
3.2
499.20
1089.67
u/ml
—
10
118
24
218
1.10
0.13
1.3
1.2
—
—
—
0
0
9
110
0.82
0.13
1.6
1.2
—
—
—
0
0
31
333
0.93
0.11
1.2
1.2
—
11.55
—
0
11
21
230
0.91
0.11
1.3
1.2
—
—
—
0
0
11
125
0.88
0.10
3.0
2.9
—
—
—
0
0
12
106
1.13
0.09
1.2
1.3
—
—
—
0
0
13
117
1.11
0.08
1.5
2.6
12.41
9.63
mg/l
—
7
95
11
98
1.12
0.07
1.2
1.2
—
—
—
0
0
42
403
1.04
0.06
3.6
2.7
4.36
2.28
index
1.44
25
236
9
105
0.86
0.06
1.1
1.1
—
—
—
0
0
9
105
0.86
0.06
1.1
1.1
—
—
—
0
0
10
111
0.90
0.06
1.1
1.1
—
—
—
0
0
10
110
0.91
0.05
1.5
1.2
—
—
—
0
0
40
414
0.97
0.05
3.5
3.5
36.22
38.66
umol/l
0.26
40
391
12
111
1.08
0.04
1.2
1.1
208.63
215.57
iu/ml
0.05
12
111
27
281
0.96
0.04
1.5
1.9
3.30
3.29
iu/l
0.00
12
117
42
408
1.03
0.04
9.0
2.8
0.97
0.89
nmol/l
0.41
36
361
40
412
0.97
0.04
3.5
2.0
—
—
—
0
0
18
171
1.05
0.03
1.1
1.1
—
—
—
0
0
78
790
0.99
0.02
1.4
2.3
40.80
40.46
u/l
0.05
69
723
10
107
0.93
0.02
1.9
2.4
—
—
—
0
0
59
583
1.01
0.01
2.8
2.7
518.97
432.49
ug/l
0.19
59
558
129
1283
1.01
0.00
3.8
3.3
—
—
—
0
0
15
145
1.03
0.00
1.1
1.3
0.73
0.68
ratio
—
10
90
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
96
1.04
0.00
1.0
1.1
—
—
—
0
0
10
103
0.97
0.00
1.1
1.1
—
—
—
0
0
21
207
1.01
0.00
1.1
1.1
—
—
—
0
0
7
71
0.99
0.00
2.4
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
68
0.88
0.00
2.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
4.60
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.1
—
—
—
0
0
64
640
1.00
-0.00
1.5
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.0
—
0.46
—
0
7
6
69
0.87
-0.00
4.2
2.5
0.60
0.61
mmol/l
—
6
69
5
55
0.91
-0.00
1.2
1.8
—
—
—
0
0
6
67
0.90
-0.00
1.8
1.5
—
—
—
0
0
5
54
0.93
-0.00
1.6
1.3
166.00
115.71
nmol/l
—
5
38
0
6
0.00
-0.00
0.0
1.0
—
2.67
—
0
6
6
59
1.02
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_MALEINFERT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_MALEINFERT | 0.764 [0.66, 0.88] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 16070 males with N14_MALEINFERT died.
Mortality risk
Mortality risk for people of age
years, who have N14_MALEINFERT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.133% |
| 5 | No data | 0.87% |
| 10 | No data | 2.112% |
| 15 | No data | 4.228% |
| 20 | No data | 7.232% |
Relationships between endpoints
↥Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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