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Carcinoma in situ of rectum

CD2_INSITU_RECTUM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • not C3_RECTUM
553012

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D01.2&
  • Hospital discharge: ICD-9 2304
  • Cause of death: ICD-10 D01.2&
  • Cause of death: ICD-9 2304
  • Cancer registry: Topography ICD-O-3 C20
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

516

4. Check minimum number of events

None

516

5. Include endpoints

None

516

6. Filter based on genotype QC (FinnGen only)

465

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D01
Name in latin
Carcinoma in situ hepatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 465 179 286
Unadjusted period prevalence (%) 0.11 0.06 0.13
Median age at first event (years) 70.20 70.14 70.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
481
Matched controls
4810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
102.4
307.7
343
114
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
19.1
229.7
233
226
8263/2-C20.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of rectum, NOS
+∞
225.3
198
*
C209, 8148, 2
ICD-O-3
1681.3
135.2
125
*
C209, 8211, 2
ICD-O-3
+∞
125.7
115
*
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
45.8
123.1
74
19
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
9.2
97.7
142
209
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
7.9
68.3
107
168
K62.1
ICD-10 Finland
Rectal polyp
22.7
68.0
51
25
UJG02
NOMESCO Finland
Proctoscopy
14.4
57.2
54
42
UJF32
NOMESCO Finland
Coloscopy
4.3
56.0
252
974
K63.5
ICD-10 Finland
Polyp of colon
10.7
55.4
64
68
WX402
NOMESCO Finland
General anaesthesia
4.2
52.0
210
743
JGA73
NOMESCO Finland
Transanal excision of lesion of rectum
111.4
46.8
50
5
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
136.0
46.7
49
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
12.1
34.8
36
32
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
5.6
31.3
64
128
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
9.0
29.1
37
44
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
6.1
28.5
52
93
C209, 8213, 2
ICD-O-3
+∞
28.4
27
*
JFF23
NOMESCO Finland
Transversostomy
10.9
25.6
28
27
JGA75
NOMESCO Finland
Endoscopic microsurgical excision of lesion of rectum
+∞
25.2
24
*
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
4.9
23.3
54
120
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
6.6
22.7
38
62
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.6
22.3
57
137
UJF32, ,
SPAT
5.3
21.8
46
94
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
52.6
21.3
25
5
UJF30
NOMESCO Finland
Ileoscopy through colon
3.1
18.4
87
318
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
16.5
140
688
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
13.5
15.9
27
21
D01.2
ICD-10 Finland
Carcinoma in situ: Rectum
+∞
15.7
15
*
8140/2-C20.9
ICD-O-3
Adenocarcinoma in situ, NOS, of rectum, NOS
+∞
15.7
15
*
R4110
NOMESCO Finland
Physiotherapy
2.2
14.9
173
967
JG1BG
NOMESCO Finland
MRI of rectum
19.1
14.8
22
12
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.3
13.8
55
180
JG1CG
NOMESCO Finland
Extensive MRI of rectum
18.9
13.5
20
11
Z12.1
ICD-10 Finland
Special screening examination for neoplasm of intestinal tract
5.8
13.0
24
43
JN4AD
NOMESCO Finland
Body CT examination
2.5
12.5
94
432
JFA15, ,
SPAT
16.4
12.2
19
12
TJF80
NOMESCO Finland
Ostomy education
12.9
12.2
21
17
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
6.2
12.2
21
35
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
14.1
11.5
19
14
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
11.4
86
395
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
36.0
11.3
14
*
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
5.4
10.7
21
40
TJG20
NOMESCO Finland
Transanal irrigation
61.4
10.7
12
*
B01AB05
ATC
enoxaparin; parenteral
1.9
10.0
182
1165
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
9.7
132
766
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
18.0
9.4
14
8
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.0
9.3
26
67
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.8
9.2
47
178
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
4.7
9.1
21
46
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
12.9
8.9
15
12
B01AB10
ATC
tinzaparin; parenteral
2.3
8.4
71
341
JGA96
NOMESCO Finland
Other proctotomy or local operation on rectum
+∞
8.4
8
*
WX600
NOMESCO Finland
Single shot through catheter
8.3
8.1
17
21
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
7.0
8.1
19
28
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
18.7
7.6
11
6
JGA87, ,
NOMESCO Finland
+∞
7.3
7
*
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
6.2
7.1
18
30
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.2
6.8
27
88
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
22.9
6.7
9
*
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
8.9
6.6
13
15
Z71.8
ICD-10 Finland
Other specified counselling
1.7
6.0
162
1130

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
325
555
15.97
215.69
2.1
1.3
—
—
—
0
0
222
576
6.30
87.43
3.9
4.5
12.78
36.22
ug/l
0.86
170
477
353
2112
3.52
34.10
3.6
2.9
—
—
estimate
—
0
0
334
2099
2.93
26.36
6.5
5.6
35.41
35.32
g/l
0.13
328
1975
142
590
3.00
24.52
1.4
1.3
—
—
—
0
0
354
2343
2.93
24.43
14.2
14.2
1.21
1.26
inr
1.01
270
1933
219
1146
2.67
24.24
3.6
2.5
—
—
—
0
0
135
557
2.98
23.50
2.2
3.1
6.55
9.05
umol/l
1.19
127
503
259
1513
2.54
22.25
3.2
2.5
—
—
—
0
0
221
1243
2.44
20.03
1.4
1.3
—
—
—
0
0
273
1691
2.42
19.85
2.6
2.2
—
—
—
0
0
109
439
2.92
19.49
2.0
2.5
38.20
32.14
u/l
1.12
90
373
116
498
2.75
18.30
2.3
2.4
0.23
0.21
g/l
2.32
110
472
348
2467
2.49
17.78
8.2
7.6
12.83
12.34
umol/l
0.19
336
2364
373
2742
2.60
17.40
6.5
5.6
6.74
6.79
mmol/l
0.17
365
2635
285
1923
2.18
15.35
3.7
3.0
126.32
158.78
ug/l
1.28
270
1780
235
1515
2.08
13.75
3.4
3.8
30.86
35.28
u/l
1.00
228
1427
152
833
2.21
13.57
3.2
2.7
12.96
12.80
umol/l
0.07
152
776
137
725
2.24
13.29
3.2
2.6
22.00
22.73
%
0.19
137
676
197
1224
2.03
12.42
2.7
2.2
2.59
2.99
mg/l
1.84
179
1069
203
1276
2.02
12.38
3.4
3.4
—
0.00
estimate
—
0
7
415
3415
2.57
11.88
11.4
9.2
83.19
81.06
u/l
0.31
409
3236
227
1527
1.92
11.01
6.8
6.3
—
—
—
0
0
209
1371
1.93
10.91
3.7
3.4
0.74
0.50
e6/l
0.27
153
1020
249
1740
1.89
10.63
4.8
4.2
124.57
123.30
e6/l
0.01
180
1279
231
1586
1.88
10.32
4.1
3.5
43.17
94.17
e6/l
0.63
173
1238
138
800
2.02
10.21
3.3
3.2
0.82
1.33
e6/l
1.10
69
414
88
432
2.27
9.99
9.8
9.3
—
—
—
0
0
462
4112
4.13
9.76
24.2
18.4
30.70
26.23
mg/l
1.91
422
3436
473
4389
5.67
9.43
33.4
24.4
86.41
81.96
umol/l
1.21
473
4351
112
625
2.03
9.10
2.9
2.8
1.80
1.81
%
0.03
104
568
89
462
2.14
8.74
8.5
8.0
1.09
1.36
mmol/l
2.00
89
455
54
228
2.54
8.52
2.2
2.5
—
—
—
0
0
300
2324
1.77
8.26
6.9
6.7
0.19
0.20
e9/l
0.38
250
2029
108
617
1.97
8.14
7.7
8.5
7.42
7.42
ph
0.25
39
372
90
483
2.06
8.07
1.8
2.2
229.62
155.74
ug/g
0.50
73
394
107
614
1.96
7.94
7.7
8.6
0.31
0.84
mmol/l
0.67
94
507
275
2092
1.73
7.93
7.0
6.6
0.60
0.68
%
1.78
263
1960
90
487
2.04
7.88
3.3
2.9
67.55
69.78
e9/l
0.27
60
377
473
4438
4.96
7.79
38.0
27.7
4.38
4.48
e12/l
4.33
455
4349
473
4438
4.96
7.79
38.0
27.8
6.79
6.83
e9/l
0.15
455
4347
473
4436
4.98
7.79
38.1
27.8
238.35
241.13
e9/l
0.45
459
4363
274
2099
1.71
7.56
6.9
6.7
9.33
9.02
%
0.82
262
1970
276
2120
1.71
7.52
2.4
2.2
92.61
94.46
pmol/l
0.27
175
1136
291
2269
1.72
7.49
6.6
6.5
0.04
0.04
e9/l
0.04
240
1944
257
1939
1.70
7.47
2.5
2.4
78.14
76.85
nmol/l
0.30
242
1712
273
2095
1.70
7.43
6.9
6.6
2.64
2.89
%
1.08
260
1962
107
629
1.90
7.35
1.3
1.3
—
—
—
0
0
165
1109
1.74
7.29
3.0
2.8
3.52
3.91
e6/l
0.29
142
1013
293
2300
1.70
7.25
6.6
6.5
1.78
2.01
e9/l
0.93
245
2028
315
2526
1.72
7.16
10.0
10.4
4.31
4.17
e9/l
0.36
252
2199
275
2127
1.68
7.16
6.8
6.7
24.89
26.62
%
1.85
264
2016
287
2261
1.67
6.82
6.6
6.5
0.63
0.61
e9/l
0.67
236
1933
60
296
2.17
6.65
1.2
1.2
—
—
—
0
0
80
440
1.98
6.65
1.7
1.5
—
—
—
0
0
297
2372
1.66
6.59
9.3
8.0
1.20
1.21
mmol/l
1.64
267
2061
273
2136
1.64
6.56
7.5
7.2
1.20
1.21
mmol/l
1.18
264
1969
268
2096
1.63
6.37
6.8
6.5
59.71
57.78
%
1.87
262
2001
50
233
2.28
6.36
2.6
3.9
32.57
6194.49
u/ml
0.83
42
202
458
4200
2.89
6.28
6.6
6.4
2.60
2.61
mmol/l
0.11
430
3860
197
1432
1.64
6.28
1.8
1.7
19.81
20.32
nmol/l
0.19
176
1184
250
1943
1.60
5.95
14.6
12.6
0.00
0.00
e9/l
0.53
191
1586
177
1271
1.62
5.83
3.0
3.1
358.91
357.72
umol/l
0.05
154
1108
125
832
1.68
5.50
3.7
3.7
0.80
0.82
mmol/l
1.17
117
789
135
917
1.66
5.49
1.3
1.2
2.99
1.38
u/ml
0.60
32
259
424
3810
1.95
5.41
5.8
5.1
1.89
1.97
mu/l
0.66
399
3448
449
4121
2.35
5.39
5.7
5.6
4.52
4.51
mmol/l
0.09
427
3811
330
2774
1.60
5.36
4.6
3.7
63.42
58.49
u/l
0.29
311
2603
136
937
1.63
5.20
3.4
3.2
522.00
551.47
mosm/kgh2o
0.93
111
823
136
938
1.63
5.17
3.9
4.3
487.84
392.32
ng/l
0.15
116
788
190
1422
1.56
5.09
3.8
4.7
7.39
7.40
ph
0.34
132
1019
446
4103
2.20
4.97
5.5
5.5
1.43
1.42
mmol/l
0.13
418
3761
337
2876
1.57
4.86
5.3
4.8
4404.14
736.24
e6/l
—
7
50
173
1282
1.55
4.78
3.9
3.3
0.72
0.78
ug/l
0.47
128
857
378
3328
1.63
4.65
31.7
23.8
330.21
332.32
g/l
4.11
378
3316
280
2312
1.51
4.57
4.0
4.0
0.00
3.30
estimate
0.50
60
492
232
1844
1.50
4.55
3.4
3.6
6.01
6.19
ph
1.78
121
1059
439
4041
1.99
4.47
7.6
7.2
39.75
40.06
mmol/mol
0.32
417
3766
186
1417
1.51
4.46
5.7
4.6
—
—
—
0
0
359
3134
1.57
4.45
4.6
4.1
15.07
14.97
pmol/l
0.33
337
2822
175
1335
1.49
4.09
3.3
3.3
—
—
—
0
0
100
676
1.61
4.04
7.0
6.4
1.03
1.02
mmol/l
0.13
95
629
203
1601
1.46
3.99
3.5
3.4
1508.78
1352.32
ng/l
0.26
187
1384
442
4104
1.95
3.98
5.8
5.7
6.07
6.09
mmol/l
0.08
418
3747
274
2289
1.46
3.97
4.1
4.0
0.00
0.00
estimate
-0.00
63
481
278
2337
1.45
3.85
4.1
4.0
0.00
0.67
estimate
0.51
57
452
118
840
1.54
3.80
1.4
1.5
2.54
2.74
g/l
0.43
67
507
230
1871
1.44
3.77
2.0
2.0
1.31
1.34
mmol/l
0.18
200
1536
111
791
1.52
3.54
3.2
2.1
29.27
29.18
s
0.05
111
770
12
32
3.82
3.41
1.0
1.1
2.13
1.71
u/ml
—
5
14
58
361
1.69
3.23
1.9
2.9
—
—
—
0
0
73
484
1.60
3.18
2.3
2.4
12.56
13.45
nmol/l
0.43
67
429
12
36
3.39
3.04
1.2
1.5
—
—
—
0
0
63
408
1.63
3.02
1.5
1.5
—
—
—
0
0
423
3937
1.62
2.99
4.7
4.7
1.32
1.32
mmol/l
0.01
395
3591
183
1477
1.39
2.95
3.0
2.7
63.94
116.63
u/l
0.48
171
1378
446
4212
1.81
2.94
21.2
16.6
—
—
—
0
0
9
22
4.15
2.89
2.2
2.5
443.89
851.23
u/ml
—
9
22
254
2168
1.36
2.86
7.0
5.8
2.40
2.57
ug/l
0.23
235
1959
22
103
2.19
2.85
3.5
3.5
10.92
375.92
u/ml
0.90
16
97
205
1712
1.34
2.58
4.4
4.2
19.86
9.81
mg/mmol
1.08
131
1091
192
1588
1.35
2.57
4.6
3.8
2.35
2.35
mmol/l
0.25
179
1432
33
187
1.82
2.56
2.0
4.7
57.69
87.83
mg/l
0.42
26
159
33
187
1.82
2.56
1.9
4.7
36.77
43.51
mg/l
0.21
26
161
102
761
1.43
2.54
2.1
2.0
—
—
—
0
0
27
148
1.87
2.33
1.1
1.2
—
—
—
0
0
165
1352
1.34
2.31
6.6
6.5
—
—
—
0
0
62
432
1.50
2.19
2.1
2.0
0.00
0.04
estimate
0.49
12
84
26
144
1.85
2.19
1.4
1.5
261.39
264.64
ug/g
0.03
18
85
30
174
1.77
2.19
1.9
4.2
2.50
2.70
ratio
0.07
16
98
17
81
2.14
2.15
3.6
2.4
34.88
33.02
pg
1.63
17
81
17
81
2.14
2.15
1.4
1.1
—
—
—
0
0
196
1674
1.29
1.97
3.8
3.5
104.65
56.69
mg/l
1.06
133
1102
150
1240
1.30
1.92
4.1
3.4
0.00
0.07
estimate
0.52
48
384
199
1708
1.28
1.91
3.7
3.5
7.80
7.80
mmol/l
0.00
174
1427
34
214
1.63
1.88
1.6
1.8
—
—
—
0
0
5
12
4.20
1.82
1.8
1.7
6.15
8.62
mmol/l
—
5
12
9
35
2.60
1.81
1.0
1.2
—
—
—
0
0
40
265
1.56
1.80
1.1
1.3
—
—
—
0
0
78
593
1.38
1.75
1.5
1.5
—
—
—
0
0
5
13
3.87
1.72
2.2
1.1
27.40
26.38
s
—
5
13
10
44
2.30
1.56
1.0
1.2
—
—
—
0
0
33
218
1.55
1.53
3.2
2.9
—
—
—
0
0
27
172
1.60
1.46
1.2
1.3
—
—
—
0
0
14
73
1.95
1.45
1.1
1.1
—
—
—
0
0
9
40
2.27
1.40
1.0
1.2
—
—
—
0
0
13
67
1.97
1.39
2.1
3.1
2.06
1.12
g/24h
—
8
45
19
112
1.73
1.37
3.6
3.4
0.88
0.87
nmol/l
0.03
14
92
18
105
1.74
1.35
4.7
3.7
—
—
—
0
0
12
61
1.99
1.34
1.4
1.4
907.14
1665.28
e6/l
—
7
40
0
40
0.00
1.33
0.0
1.3
—
—
—
0
0
117
982
1.25
1.30
1.8
1.8
451.91
19287907.05
pmol/l
0.69
100
814
115
964
1.25
1.29
4.0
3.2
2.48
2.45
mmol/l
1.07
110
873
11
55
2.02
1.28
1.5
1.4
—
—
—
0
0
87
706
1.28
1.27
1.3
1.3
5.64
13.81
u/ml
1.09
29
253
93
763
1.27
1.25
1.3
1.3
15.19
39.31
iu/ml
3.69
27
236
6
25
2.42
1.24
1.0
1.5
252.33
353.17
mu/l
—
6
18
171
1502
1.21
1.23
2.1
2.3
147.71
248.52
u/l
1.23
162
1427
8
37
2.18
1.22
1.9
1.9
—
—
—
0
0
23
149
1.57
1.19
1.5
1.6
10.62
15.03
u/ml
—
6
27
49
370
1.36
1.19
2.3
2.5
5.88
6.06
ph
0.66
33
255
11
57
1.95
1.18
1.6
1.1
1.67
4.04
u/ml
—
6
25
7
138
0.50
1.11
16.6
11.6
—
—
—
0
0
73
592
1.27
1.08
1.3
1.3
370.91
544.06
titre
0.33
11
138
10
52
1.94
1.07
1.7
1.2
—
—
—
0
0
7
34
2.07
1.03
1.6
1.0
—
—
—
0
0
10
53
1.91
1.02
1.1
1.1
—
—
—
0
0
36
266
1.38
1.01
1.2
1.4
—
48.10
—
0
21
9
49
1.85
0.99
1.3
1.2
—
—
—
0
0
13
77
1.71
0.96
2.8
2.7
4.41
4.66
e9/l
0.14
13
77
193
1751
1.17
0.93
4.1
4.0
0.00
0.01
estimate
0.50
50
406
37
281
1.34
0.90
1.4
1.4
—
—
—
0
0
15
95
1.60
0.88
1.3
1.6
—
—
—
0
0
30
222
1.37
0.86
1.3
1.3
—
—
—
0
0
10
57
1.77
0.84
1.1
1.3
—
—
—
0
0
10
57
1.77
0.84
1.0
1.2
—
—
—
0
0
113
990
1.18
0.82
3.2
1.7
2.07
1.35
mg/l
1.00
98
791
62
512
1.24
0.82
4.7
3.6
7.38
7.38
ph
0.13
33
306
14
89
1.59
0.82
1.4
1.2
—
—
—
0
0
13
81
1.62
0.82
7.3
5.4
11.12
10.86
mg/l
0.09
13
75
23
164
1.42
0.81
1.6
3.2
43.65
36.41
u/ml
0.12
23
159
18
122
1.49
0.81
1.4
1.8
—
—
—
0
0
6
33
1.83
0.79
1.2
1.9
—
—
—
0
0
170
1544
1.16
0.79
3.7
3.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
131.69
—
0
16
8
48
1.68
0.79
1.3
1.1
—
—
—
0
0
8
48
1.68
0.79
1.8
1.1
—
—
—
0
0
96
833
1.19
0.78
1.9
1.8
1059.14
1199.44
nmol/l
0.72
75
646
0
27
0.00
0.77
0.0
1.6
—
0.98
—
0
17
34
262
1.32
0.77
1.7
1.5
—
—
—
0
0
19
132
1.46
0.77
3.1
2.5
245.15
95.95
ug/min
—
10
73
20
277
0.71
0.75
3.8
2.5
1.06
1.18
%
0.45
20
277
108
951
1.17
0.75
4.2
5.4
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
14
92
1.54
0.73
1.6
1.3
47.71
60.69
mmol/l
0.70
14
84
7
39
1.81
0.72
2.1
3.5
129.26
58.40
u/ml
—
7
39
9
57
1.59
0.71
1.1
1.3
—
—
—
0
0
9
57
1.59
0.71
1.3
1.8
—
—
—
0
0
9
57
1.59
0.71
1.4
1.5
—
—
—
0
0
5
26
1.93
0.71
1.2
1.3
—
—
—
0
0
58
486
1.22
0.69
4.9
3.5
1.59
1.82
mmol/l
0.15
53
413
10
61
1.65
0.69
1.1
2.8
—
—
—
0
0
10
61
1.65
0.69
1.1
1.2
—
—
—
0
0
10
61
1.65
0.69
1.2
1.2
—
—
—
0
0
10
61
1.65
0.69
1.1
1.2
—
—
—
0
0
7
42
1.68
0.68
3.7
2.0
—
—
—
0
0
5
27
1.86
0.68
2.6
2.4
2.36
3.86
ug/l
—
5
27
7
119
0.58
0.68
1.4
1.2
—
—
—
0
0
8
49
1.64
0.62
1.3
1.1
—
—
—
0
0
5
30
1.67
0.61
5.2
1.7
192.60
103.10
ng/l
—
5
30
8
50
1.61
0.61
1.4
1.2
—
—
—
0
0
29
227
1.30
0.61
2.7
2.1
0.00
3.86
estimate
—
9
65
0
20
0.00
0.60
0.0
1.6
—
1.26
—
0
14
0
21
0.00
0.60
0.0
3.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
6.97
—
0
21
0
21
0.00
0.60
0.0
1.7
—
61.07
—
0
15
51
429
1.21
0.60
1.5
1.6
—
—
—
0
0
52
441
1.20
0.57
2.2
2.6
6.60
7.85
ug/l
0.37
44
402
15
107
1.41
0.56
3.1
2.6
58.33
58.21
%
0.01
15
107
10
65
1.55
0.56
1.2
1.2
59.92
78.42
mu/l
—
10
59
16
116
1.39
0.55
1.8
1.6
—
—
—
0
0
9
60
1.51
0.54
1.4
1.3
0.62
32.05
nmol/l
—
9
54
13
91
1.44
0.53
3.5
3.6
11.09
9.94
pmol/l
0.21
13
91
30
242
1.26
0.52
1.2
1.3
—
—
—
0
0
63
554
1.16
0.47
1.6
1.6
—
—
—
0
0
13
95
1.38
0.44
1.3
1.2
42.58
33.51
u/l
0.17
13
79
16
122
1.32
0.43
1.2
1.1
—
—
—
0
0
23
185
1.26
0.42
1.2
1.1
—
—
—
0
0
56
494
1.15
0.41
1.5
1.6
—
—
—
0
0
41
353
1.18
0.40
3.6
3.5
7.42
7.42
ph
0.29
35
300
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
5
34
1.48
0.40
1.0
2.1
—
—
—
0
0
5
35
1.43
0.39
2.8
3.5
1.60
0.94
index
—
5
35
0
19
0.00
0.39
0.0
3.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
17.59
—
0
7
9
68
1.33
0.38
1.3
1.3
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
320.00
—
0
5
9
70
1.29
0.37
2.0
4.2
32.22
28.59
u/ml
—
9
70
11
81
1.37
0.36
1.0
1.1
—
—
—
0
0
38
329
1.17
0.36
3.0
5.3
—
—
—
0
0
6
45
1.34
0.34
1.5
1.2
—
—
—
0
0
6
45
1.34
0.34
1.2
1.1
—
—
—
0
0
12
92
1.31
0.32
2.3
1.7
7.24
4.60
iu/l
—
6
38
47
420
1.13
0.31
4.5
5.4
1.86
0.09
%
0.47
14
125
7
56
1.25
0.29
2.7
2.1
87.46
89.75
%
—
7
56
7
57
1.23
0.29
1.4
1.3
—
—
—
0
0
15
121
1.25
0.29
1.2
1.2
—
2.75
—
0
19
109
1024
1.08
0.28
4.0
4.1
1.02
1.02
kg/l
0.15
79
697
46
413
1.13
0.28
4.3
5.0
0.00
0.11
%
3.33
13
138
13
103
1.27
0.28
1.5
1.3
0.96
0.91
g/l
0.26
13
103
10
127
0.78
0.25
4.9
4.8
—
—
—
0
0
39
350
1.12
0.25
5.5
3.9
—
—
—
0
0
11
87
1.27
0.24
1.7
1.2
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
0.13
—
0
6
5
40
1.25
0.22
2.4
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
5
43
1.16
0.21
1.6
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
15
127
1.19
0.20
1.5
1.8
163.60
205.50
pmol/l
1.22
15
117
6
52
1.16
0.19
1.2
1.2
—
—
—
0
0
23
204
1.13
0.18
1.4
1.2
140.27
111.73
u/ml
—
9
73
7
59
1.19
0.18
2.7
2.0
13.57
10.72
mmol/l
—
7
59
9
81
1.11
0.15
1.2
1.2
—
0.70
—
0
15
7
87
0.80
0.14
2.0
2.1
5.41
4.98
mmol/24h
—
7
78
20
179
1.12
0.14
1.3
1.4
—
—
—
0
0
8
98
0.81
0.14
1.3
1.4
—
—
—
0
0
21
190
1.11
0.13
3.6
2.1
945.10
501.19
ug/l
0.28
21
182
176
1720
1.04
0.12
4.1
3.9
—
1.00
—
0
5
26
239
1.09
0.12
1.6
1.9
3.94
3.40
mmol/l
0.94
20
190
11
95
1.16
0.11
1.6
1.2
3.21
3.73
mmol/l
2.15
11
89
11
95
1.16
0.11
1.2
1.2
1.71
1.53
g/l
0.82
11
95
11
95
1.16
0.11
1.5
1.9
—
—
—
0
0
136
1326
1.04
0.11
4.5
4.0
0.00
0.01
estimate
0.78
55
439
5
45
1.11
0.10
1.6
2.1
—
—
—
0
0
13
116
1.12
0.09
1.7
1.2
620.08
510.80
mg/l
0.29
13
110
5
48
1.04
0.09
1.2
1.4
27.20
29.14
ng/l
—
5
48
46
440
1.05
0.08
3.0
2.2
396.20
374.84
nmol/l
0.30
46
414
5
63
0.79
0.08
1.0
1.1
—
52.23
—
0
13
57
549
1.04
0.08
2.0
1.7
—
—
—
0
0
46
441
1.05
0.08
4.3
4.8
0.38
0.81
%
1.26
13
166
8
75
1.07
0.07
1.1
1.7
—
—
—
0
0
8
75
1.07
0.07
1.1
1.7
—
—
—
0
0
8
75
1.07
0.07
1.1
1.7
—
—
—
0
0
8
75
1.07
0.07
1.1
1.7
—
—
—
0
0
186
1887
0.98
0.07
4.0
4.2
36.13
67.83
ng/l
0.58
145
1471
7
84
0.83
0.07
1.0
1.4
—
224.31
—
0
30
9
88
1.02
0.07
4.3
2.5
—
—
—
0
0
44
457
0.96
0.06
6.3
4.4
7.37
7.34
ph
1.04
31
326
22
207
1.07
0.06
1.8
1.6
0.28
0.40
mg/l
0.58
12
100
14
130
1.08
0.04
1.5
1.7
—
—
—
0
0
43
417
1.03
0.04
4.4
4.8
0.82
0.37
%
0.44
11
149
12
111
1.08
0.04
1.1
1.1
—
—
—
0
0
46
472
0.97
0.03
1.4
1.5
—
—
—
0
0
20
191
1.05
0.03
3.7
4.3
1.43
1.40
mmol/l
0.04
20
185
26
252
1.03
0.02
3.2
3.7
—
—
—
0
0
10
94
1.07
0.01
1.2
1.4
—
—
—
0
0
22
214
1.03
0.00
1.3
1.3
—
—
—
0
0
11
114
0.96
0.00
1.0
1.2
—
—
—
0
0
18
176
1.02
0.00
3.0
3.2
443.18
255.22
mg/l
0.30
11
78
14
137
1.02
0.00
2.6
3.5
5.57
2.01
index
—
7
84
58
576
1.01
0.00
2.4
3.3
6.59
5.63
e9/l
0.20
52
504
16
161
0.99
0.00
1.7
1.8
30.37
41.79
nmol/l
1.50
16
150
7
77
0.91
0.00
1.9
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
0.43
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
17.90
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
41.63
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
2.0
2.3
—
27.61
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
51
0.98
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.6
—
8.11
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
-0.00
3.8
4.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
0.91
—
0
8

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_RECTUM – Carcinoma in situ of rectum

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).