Alcohol induced polyneuropathy

G6_ALCOPOLY

alcoholic neuropathy: A condition where damage to the peripheral nervous system (including the peripheral elements of the autonomic nervous system) is associated with chronic ingestion of alcoholic beverages. The disorder may be caused by a direct effect of alcohol, an associated nutritional deficiency, or a combination of factors. Clinical manifestations include variable degrees of weakness; ATROPHY; PARESTHESIAS; pain; loss of reflexes; sensory loss; diaphoresis; and postural hypotension. (From Arch Neurol 1995;52(1):45-51; Adams et al., Principles of Neurology, 6th ed, p1146)

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G62.1
  • Hospital discharge: ICD-9 3575A
  • Cause of death: ICD-10 G62.1
  • Cause of death: ICD-9 3575A

2 out of 7 registries used, show all original rules.

398

4. Check minimum number of events

None

398

5. Include endpoints

None

398

6. Filter based on genotype QC (FinnGen only)

371

Control definitions (FinnGen only)

Control exclude
G6_POLYNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G62
Name in latin
Polyneuropathia alcoholica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4609 835 3665
Only index persons 3095 628 2467
Unadjusted period prevalence (%)
Whole population 0.09 0.02 0.10
Only index persons 0.08 0.02 0.09
Median age at first event (years)
Whole population 57.12 56.02 57.32
Only index persons 57.57 57.05 57.70

-FinnGen-

Key figures

All Female Male
Number of individuals 371 78 293
Unadjusted period prevalence (%) 0.11 0.03 0.13
Median age at first event (years) 58.88 57.46 59.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
380
Matched controls
3800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
8370.4
307.7
350
5
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
24.3
223.4
209
182
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
131.9
221.0
112
12
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
62.1
125.8
71
14
F10.20
ICD-10 Finland
Alcohol dependence currently independent
28.8
116.2
82
36
F10.25
ICD-10 Finland
Alcohol dependence continuous use
22.8
106.7
83
46
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
30.5
99.5
68
27
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
17.3
98.0
88
65
F10.24
ICD-10 Finland
Alcohol depence active use
25.1
88.5
65
31
P15
ICPC
Chronic alcohol abuse
14.1
84.2
85
76
N07BB01
ATC
disulfiram; oral
9.8
65.3
85
108
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
23.2
62.8
47
23
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
19.2
60.2
49
29
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
21.5
57.1
44
23
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
24.0
53.2
39
18
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
14.4
47.7
45
35
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
14.0
46.9
45
36
N05BA02
ATC
chlordiazepoxide; systemic
10.8
44.3
51
54
N05CD07
ATC
temazepam; oral
5.2
41.1
105
261
N05AH04
ATC
quetiapine; oral
4.4
38.2
128
393
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.2
37.9
146
496
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.9
37.4
193
801
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
15.1
35.2
32
23
3575A
ICD-9 Finland
Inflammatory and toxic neuropathy, Alcoholic polyneuropathy
+∞
34.9
33
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.1
34.4
86
208
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.6
30.4
46
68
P16
ICPC
Acute alcohol abuse
10.3
30.2
35
37
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.2
29.6
55
101
L28
ICPC
Limited function/disability (L)
3.8
29.3
120
416
K92.0
ICD-10 Finland
Haematemesis
8.8
28.2
37
46
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
7.3
27.8
43
65
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
27.0
170
765
N05CF01
ATC
zopiclone; oral
3.2
26.9
179
831
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.5
26.8
36
46
N06AB04
ATC
citalopram; systemic
3.5
26.5
123
459
F10.09
ICD-10 Finland
Alcohol intoxication UNS
8.4
26.4
36
47
N06AX11
ATC
mirtazapine; oral
3.1
25.7
177
833
N03AX12
ATC
[U] gabapentin; oral
3.6
24.8
105
368
N05BA01
ATC
diazepam; systemic, rectal
3.9
24.8
88
274
E87.6
ICD-10 Finland
Hypokalaemia
6.3
24.7
44
77
N05BA04
ATC
oxazepam; oral
3.2
24.5
140
589
D64.9
ICD-10 Finland
Anaemia, unspecified
3.8
23.9
85
265
A06AD11
ATC
lactulose; oral
3.5
23.4
98
340
K70.1
ICD-10 Finland
Alcoholic hepatitis
43.1
23.0
28
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
22.5
94
325
A28
ICPC
Limited function/disability NOS
3.2
22.4
112
433
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
18.5
22.2
34
20
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
22.1
163
783
N05AA02
ATC
levomepromazine; systemic
6.1
21.8
40
72
W19
ICD-10 Finland
Unspecified fall
3.9
20.9
69
203
S72.0
ICD-10 Finland
Fracture of neck of femur
5.8
20.4
39
73
V03AA01, ,
ATC
8.1
20.2
28
37
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
7.8
20.2
29
40
AA1AD
NOMESCO Finland
CT of head and brain
2.7
19.7
163
821
S01.0
ICD-10 Finland
Open wound of scalp
3.8
18.9
64
191
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
18.8
86
312
G62.8
ICD-10 Finland
Other specified polyneuropathies
105.3
18.7
20
*
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
17.3
18.6
29
18
N06AB10
ATC
escitalopram; oral
3.1
18.4
98
388
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
15.4
18.4
30
21
C03DA01
ATC
spironolactone; oral
3.2
18.3
87
323
K70.0
ICD-10 Finland
Alcoholic fatty liver
24.2
18.0
25
11
A46
ICD-10 Finland
Erysipelas
3.0
17.7
97
390
N03AX16
ATC
[U] pregabalin
2.8
17.5
119
537
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
17.0
99
411
C03CA01
ATC
furosemide; systemic
2.5
16.8
165
889
S42.2
ICD-10 Finland
Fracture of upper end of humerus
5.3
16.8
35
71
K70.4
ICD-10 Finland
Alcoholic hepatic failure
42.1
16.5
20
5
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
5.8
16.5
31
57
Z2446
NOMESCO Finland
Social worker
4.2
16.4
47
124
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
25.8
16.2
22
9
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.2
15.7
44
114
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
30.0
15.3
20
7
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
13.2
15.1
26
21
Z3226
NOMESCO Finland
Physiotherapist
2.8
14.9
93
398
R18
ICD-10 Finland
Ascites
6.7
14.7
24
38
R53
ICD-10 Finland
Malaise and fatigue
2.5
14.7
121
593
N30.0
ICD-10 Finland
Acute cystitis
3.2
14.6
65
230
N06AX16
ATC
venlafaxine; oral
3.1
14.5
71
266
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
15.2
14.2
23
16
N06AA09
ATC
amitriptyline; systemic
3.4
13.7
53
172
N03AF01
ATC
carbamazepine; oral, rectal
4.2
13.6
38
98
Z72.1
ICD-10 Finland
Alcohol use
10.3
13.4
26
27
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
13.4
68
259
N06AB03
ATC
fluoxetine; oral
3.0
13.1
67
256
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
13.1
49
155
R60.0
ICD-10 Finland
Localized oedema
2.9
13.0
69
269
S97
ICPC
Chronic ulcer skin
3.4
12.7
49
158
N02AX02
ATC
tramadol; systemic, rectal
2.2
12.7
203
1303
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.1
12.7
36
94
A41.9
ICD-10 Finland
Sepsis, unspecified
4.7
12.6
30
68
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.0
12.6
28
60
ZXD05
NOMESCO Finland
Urgent procedure
2.3
12.4
139
772
N02BF01
ATC
gabapentin; oral
3.2
12.3
53
183
F34.1
ICD-10 Finland
Dysthymia
5.0
12.3
27
57
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.3
12.3
21
35
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
9.1
12.2
25
29
N06AX21
ATC
duloxetine; oral
3.0
12.1
58
214
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
12.0
98
473
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
6.1
11.9
21
36
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.4
11.9
24
47
N05AH03
ATC
olanzapine; systemic
3.7
11.9
39
113
C07AA05
ATC
propranolol; systemic
2.5
11.8
87
400
Z02.7
ICD-10 Finland
Issue of medical certificate
3.4
11.8
44
139
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
11.8
137
770
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
11.7
40
119
N02BF02
ATC
pregabalin; oral
3.8
11.6
37
105
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.6
11.5
76
332
S22.3
ICD-10 Finland
Fracture of rib
3.1
11.5
53
191
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.8
11.3
36
102
S82.6
ICD-10 Finland
Fracture of lateral malleolus
3.8
11.0
35
99
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
11.0
55
207
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
16.1
10.9
17
11
SPAT1265
SPAT
Breathalyser
11.0
10.9
20
19
M04AA01
ATC
allopurinol; systemic
2.5
10.9
84
394
SPAT1254
SPAT
Administration of medicine
2.6
10.8
73
322
P99
ICPC
Psychological disorders other
5.7
10.5
20
37
Z2221
NOMESCO Finland
Medical doctor
2.2
10.5
116
634
SPAT1216
SPAT
Assessment of functional ability
2.5
10.5
74
333
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
12.5
10.5
18
15
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
12.5
10.5
18
15
TKC20
NOMESCO Finland
Catheterisation of bladder
3.0
10.4
49
178
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
10.4
100
516
R4110
NOMESCO Finland
Physiotherapy
2.1
10.4
128
730
M79.6
ICD-10 Finland
Pain in limb
2.0
10.2
174
1118
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
10.1
35
105
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
10.0
71
319
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.7
10.0
59
242
N05AF03
ATC
chlorprothixene; systemic
5.4
9.9
20
39
N05AB01
ATC
dixyrazine; systemic
9.1
9.9
20
23
N05BE01
ATC
buspirone; oral
4.6
9.7
23
52
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.1
9.6
42
146
SPAT1240
SPAT
Therapeutic discussion
3.1
9.6
43
152
OAB43, ,
SPAT
0.2
9.6
10
543
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
18.1
9.5
14
8
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
4.9
9.4
21
45
ZXD35
NOMESCO Finland
Usual procedure
4.3
9.3
24
58
N06AA12
ATC
doxepin; systemic
3.6
9.3
31
91
L76
ICPC
Fracture: other
4.6
9.2
22
50
N05AD03
ATC
melperone; systemic
9.4
9.1
18
20
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
37.7
9.1
11
*
E51.2
ICD-10 Finland
Wernicke encephalopathy
37.7
9.1
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
9.0
75
362
X58
ICD-10 Finland
Exposure to other specified factors
2.4
9.0
72
342
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
8.3
9.0
19
24
S72.1
ICD-10 Finland
Pertrochanteric fracture
5.1
8.9
19
39
D07BC01
ATC
betamethasone and antiseptics; topical
2.6
8.9
56
237
N03AX09
ATC
lamotrigine; oral
4.3
8.8
23
56
SPAT1229
SPAT
Assessment of need for aid
3.1
8.8
38
131
T74.1
ICD-10 Finland
Physical abuse
14.5
8.8
14
10
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
51.2
8.7
10
*
R11
ICD-10 Finland
Nausea and vomiting
3.0
8.7
41
149
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.9
8.7
19
40
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.6
8.7
29
85
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.2
8.7
35
116
S06.0
ICD-10 Finland
Concussion
2.6
8.7
55
234
Z3231
NOMESCO Finland
Registered nurse
2.0
8.7
120
707
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
8.6
78
390
K92.1
ICD-10 Finland
Melaena
3.2
8.6
36
122
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
8.6
73
355
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.7
8.6
27
76
R5110, ,
SPAT
2.8
8.5
44
168
F10
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol
28.2
8.5
11
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.1
8.5
36
123
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
8.5
43
163
G63.2
ICD-10 Finland
Diabetic polyneuropathy
92.0
8.4
9
*
S42.0
ICD-10 Finland
Fracture of clavicle
4.3
8.4
22
54
P29
ICPC
Psychological sympt/compl other
3.4
8.3
31
98
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.1
8.3
23
59
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
14.9
8.3
13
9
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
8.2
62
286
OAA67, ,
SPAT
0.1
8.2
*
303
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
17.6
8.1
12
7
N05AX08
ATC
risperidone; systemic
2.7
8.0
44
174
K85
ICD-10 Finland
Acute pancreatitis
6.3
8.0
20
33
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
7.9
62
291
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.1
7.9
33
112
F05.9
ICD-10 Finland
Delirium, unspecified
6.1
7.8
20
34
S70.0
ICD-10 Finland
Contusion of hip
3.8
7.7
24
67
A01
ICPC
Pain general/multiple sites
2.6
7.7
47
196
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
18.8
7.6
11
6
K29.2
ICD-10 Finland
Alcoholic gastritis
25.6
7.6
10
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.4
7.6
17
24
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.7
7.5
24
68
A02BC01
ATC
omeprazole; systemic
1.9
7.5
115
697
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.9
7.5
22
59
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.6
7.4
24
69
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.5
7.4
25
74
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
11.2
7.3
13
12
K86.1
ICD-10 Finland
Other chronic pancreatitis
9.6
7.3
14
15
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
6.0
7.3
19
33
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.6
7.2
24
70
W10
ICD-10 Finland
Fall on and from stairs and steps
3.1
7.1
30
102
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
7.1
48
210
V03AB30, ,
ATC
9.0
7.1
14
16
S43.0
ICD-10 Finland
Dislocation of shoulder joint
3.6
7.1
23
66
K22.1
ICD-10 Finland
Ulcer of oesophagus
4.3
7.1
18
43
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
7.1
66
333
L17
ICPC
Foot/toe symptom/complaint
1.9
7.0
120
751
NF1AA
NOMESCO Finland
Hip X-ray examination
2.5
7.0
45
192
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
7.0
65
327
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.4
7.0
48
212
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
3.5
7.0
24
72
A98
ICPC
Health maint/preventive medicine
0.5
6.9
292
3302
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.9
94
545
J01MA02
ATC
ciprofloxacin; systemic
1.8
6.9
162
1116
N03AX14
ATC
levetiracetam; systemic
4.2
6.9
18
44
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
6.3
6.8
17
28
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
11.2
6.8
12
11
D10
ICPC
Vomiting
3.6
6.8
22
63
F32
ICD-10 Finland
Depressive episode
3.5
6.8
23
68
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
40.8
6.8
8
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.9
6.7
32
117
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
6.7
41
171
SPAT1167
SPAT
Insertion of urinary catheter
3.7
6.7
21
59
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
6.1
6.7
17
29
N06AB06
ATC
sertraline; oral
2.5
6.6
44
191
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.9
6.6
19
50
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
6.6
39
160
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
10.3
6.6
12
12
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
6.5
59
293
K76.7
ICD-10 Finland
Hepatorenal syndrome
71.0
6.4
7
*
R95
ICPC
Chron obstructive pulmonary disease
3.3
6.4
24
76
R20.2
ICD-10 Finland
Paraesthesia of skin
2.8
6.3
32
121
WX892
NOMESCO Finland
Monitored bed care
2.5
6.3
40
170
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
+∞
6.3
6
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.4
6.2
22
67
S22.4
ICD-10 Finland
Multiple fractures of ribs
4.1
6.2
17
43
S82.0
ICD-10 Finland
Fracture of patella
7.9
6.2
13
17
N05CF02
ATC
zolpidem; oral
2.1
6.2
67
358
N07BA03
ATC
varenicline; oral
2.9
6.1
28
100
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
12.8
6.1
10
8
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
10.3
6.1
11
11
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
6.1
58
1026
J01FF01
ATC
clindamycin; systemic
1.8
6.0
109
690
A02BC02
ATC
pantoprazole; systemic
1.8
6.0
267
2171

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
100
9.10
55.09
4.1
3.6
33.17
35.38
umol/l
0.32
70
93
81
183
5.35
35.11
2.9
1.8
0.58
0.40
mg/l
1.55
55
97
109
353
3.93
29.43
3.3
2.4
0.18
0.21
g/l
1.70
99
330
146
634
3.12
24.16
4.9
3.6
0.73
0.82
mmol/l
13.70
141
603
121
497
3.10
21.73
6.8
6.8
1.03
1.02
mmol/l
0.12
112
468
90
309
3.51
21.72
4.9
2.7
29.94
34.97
u/l
0.68
82
267
128
552
2.99
20.99
1.8
1.7
1033.41
1151.55
nmol/l
0.63
103
431
83
278
3.54
20.74
1.7
3.0
65.13
66.75
g/l
0.95
76
257
71
224
3.67
19.35
1.7
2.6
—
—
—
0
0
241
1513
2.62
18.00
7.7
5.7
33.02
35.28
g/l
6.31
232
1426
163
881
2.49
16.35
2.8
2.2
2.98
2.93
mg/l
0.09
147
772
46
124
4.08
15.56
1.3
2.0
10.13
11.08
g/l
0.64
40
110
82
324
2.95
15.27
12.9
10.7
—
—
—
0
0
116
550
2.60
15.18
2.8
2.1
—
—
—
0
0
87
361
2.83
14.77
6.4
3.8
1.59
1.75
mmol/l
0.12
81
308
50
149
3.71
14.68
2.9
2.1
233.18
637.41
ug/l
0.75
50
140
185
1100
2.33
14.53
3.3
2.2
355.63
273.30
u/l
0.26
180
1047
168
969
2.32
14.05
5.3
4.8
7.40
7.40
ph
0.87
126
700
88
381
2.70
13.69
6.5
3.9
7.37
7.38
ph
1.09
44
225
227
1498
2.28
13.58
2.9
2.1
89.21
94.58
pmol/l
0.94
151
837
176
1061
2.23
12.97
7.4
4.6
—
—
—
0
0
223
1493
2.19
12.45
12.1
7.5
1.18
1.20
mmol/l
4.50
212
1384
91
419
2.54
12.40
4.5
3.5
14.17
9.34
umol/l
0.93
80
378
58
1271
0.36
12.22
3.6
3.4
—
—
—
0
0
20
17
12.35
11.46
1.1
1.1
111.70
155.61
nmol/l
1.80
20
17
165
1009
2.12
11.33
2.2
1.7
16.58
19.90
nmol/l
2.76
148
851
75
328
2.60
11.29
1.9
1.7
—
—
—
0
0
90
437
2.39
10.80
2.3
1.7
—
—
—
0
0
180
1153
2.07
10.78
5.8
6.3
—
—
—
0
0
261
3147
0.46
10.68
4.9
5.4
1.39
1.37
mmol/l
0.27
234
2913
25
56
4.71
10.65
1.2
1.1
—
—
—
0
0
35
103
3.64
10.42
1.6
1.6
290.33
273.96
ug/g
0.17
21
65
89
442
2.32
10.09
1.7
1.3
—
—
—
0
0
249
3034
0.48
9.85
4.3
4.6
1.43
1.35
mmol/l
0.50
217
2797
168
1086
1.98
9.47
4.3
2.8
92.32
62.47
u/l
0.50
160
1024
25
63
4.18
9.20
1.3
1.2
—
—
—
0
0
229
1656
1.96
9.19
11.9
8.3
1.19
1.20
mmol/l
2.29
211
1440
273
3204
0.47
9.05
5.7
6.2
2.36
2.60
mmol/l
3.83
251
2973
267
3154
0.48
8.90
4.9
5.6
4.21
4.44
mmol/l
2.94
241
2944
104
577
2.10
8.86
2.8
2.6
2.08
2.26
g/l
1.94
97
534
175
1174
1.91
8.62
5.4
3.9
45.27
35.38
u/l
2.36
161
1108
86
457
2.14
8.13
2.5
2.6
2.13
1.86
%
0.78
76
418
23
60
4.02
8.09
1.3
1.1
—
—
—
0
0
136
855
1.92
8.04
4.2
3.1
—
—
—
0
0
45
181
2.69
7.92
1.9
1.5
1.61
1.52
g/l
0.25
39
161
86
462
2.11
7.89
12.1
9.2
1.33
0.73
mmol/l
0.60
76
389
302
3392
0.47
7.65
52.0
26.8
4.11
4.54
e12/l
27.69
295
3314
302
3392
0.47
7.65
51.9
26.9
7.46
6.87
e9/l
4.79
295
3314
73
372
2.19
7.64
1.9
1.6
—
—
—
0
0
302
3391
0.47
7.60
52.0
26.9
242.24
237.30
e9/l
0.52
295
3327
14
14
10.33
7.59
1.7
1.4
—
—
—
0
0
81
433
2.11
7.50
1.8
1.7
—
—
—
0
0
164
1114
1.83
7.48
3.8
2.6
—
—
—
0
0
49
213
2.49
7.37
1.5
1.6
—
—
—
0
0
148
981
1.83
7.26
4.4
3.3
0.75
0.58
e6/l
0.22
107
724
85
469
2.05
7.22
12.3
9.1
7.42
7.41
ph
0.12
46
261
22
61
3.77
7.13
1.5
1.2
69.47
60.59
mmol/l
0.32
15
54
228
1731
1.79
7.00
13.2
14.8
1.22
1.28
inr
1.03
183
1419
140
922
1.82
6.96
4.5
3.2
—
0.00
estimate
—
0
5
211
1577
1.76
6.74
6.8
6.8
0.68
0.67
%
0.05
197
1473
109
670
1.88
6.72
2.9
3.0
467.77
570.84
mosm/kgh2o
5.71
95
587
214
1611
1.75
6.61
6.6
6.8
23.03
26.39
%
4.55
199
1521
211
1583
1.75
6.59
6.8
6.8
9.27
9.15
%
0.24
196
1481
240
1869
1.77
6.56
9.3
10.9
4.92
4.23
e9/l
2.56
196
1629
224
1711
1.75
6.55
6.5
6.5
0.04
0.04
e9/l
0.04
178
1456
210
1576
1.74
6.53
6.7
6.7
2.54
2.98
%
2.33
197
1476
148
1008
1.77
6.47
6.3
6.9
—
—
—
0
0
223
1707
1.74
6.42
6.5
6.5
0.65
0.62
e9/l
0.81
176
1447
183
1328
1.73
6.37
2.5
2.4
68.50
74.13
nmol/l
1.63
163
1182
209
1575
1.73
6.33
6.6
6.7
61.23
57.80
%
3.51
198
1502
225
1733
1.73
6.27
6.5
6.6
1.71
1.96
e9/l
1.18
183
1514
73
402
2.01
6.17
1.5
1.3
453.33
424.90
titre
0.08
15
98
17
44
4.00
6.05
2.8
1.5
—
—
—
0
0
97
594
1.85
5.97
4.2
3.1
1.95
1.02
e6/l
0.40
48
316
161
1145
1.70
5.91
4.5
3.5
17.11
113.96
e6/l
1.06
117
888
12
15
8.22
5.88
1.9
1.7
1591.33
6831.89
e6/l
—
6
9
53
266
2.15
5.72
16.8
11.5
92.91
93.71
%
0.44
53
266
224
1754
1.67
5.60
7.1
6.8
0.19
0.20
e9/l
0.54
184
1529
32
131
2.58
5.45
1.1
1.1
—
—
—
0
0
16
43
3.84
5.42
1.6
1.4
2848.82
1983.62
e6/l
0.16
11
26
16
34
4.87
5.36
1.5
1.6
—
—
—
0
0
299
3315
0.54
5.31
20.9
13.2
27.88
28.04
u/l
0.06
290
3233
172
1272
1.64
5.27
5.4
4.0
75.09
96.91
e6/l
0.26
118
929
14
26
5.55
5.27
1.3
1.1
—
—
—
0
0
99
632
1.77
5.25
3.1
3.3
2.47
2.45
mmol/l
1.01
85
568
5
0
+∞
5.22
1.2
0.0
—
—
—
0
0
118
793
1.71
5.21
2.9
2.7
5.29
3.40
e6/l
1.26
103
722
11
15
7.51
5.17
2.0
1.7
—
—
—
0
0
188
1430
1.62
5.09
3.6
2.9
264.47
170.97
ug/l
1.59
175
1330
20
67
3.10
4.90
1.6
1.4
—
—
—
0
0
29
120
2.53
4.85
2.2
3.2
1.15
2.57
ratio
1.31
13
68
94
604
1.74
4.83
1.7
1.3
3.93
2.87
g/l
2.66
62
373
45
230
2.09
4.64
4.2
4.3
97.18
88.88
ng/l
0.31
38
203
63
363
1.88
4.63
2.3
2.8
75.36
71.49
e9/l
0.22
39
277
20
70
2.96
4.56
1.7
1.6
—
—
—
0
0
22
82
2.79
4.50
1.5
1.5
—
—
—
0
0
19
66
2.98
4.40
1.2
1.1
2.86
18.33
e6/l
0.73
14
49
25
101
2.58
4.39
5.0
3.4
7.63
2.02
index
0.35
16
66
14
34
4.23
4.25
1.3
1.2
—
—
—
0
0
15
39
3.96
4.24
1.5
2.1
—
—
—
0
0
19
69
2.85
4.08
1.3
1.2
47.93
1697.22
e6/l
0.52
14
55
27
119
2.37
3.97
1.4
1.2
—
—
—
0
0
166
2055
0.66
3.87
4.8
5.5
1.73
2.42
ug/l
1.67
151
1859
12
28
4.39
3.85
2.2
1.4
—
—
—
0
0
14
39
3.69
3.74
1.6
1.5
12875.43
22617.06
e6/l
—
7
17
13
34
3.92
3.73
1.2
1.3
270.50
274.30
mosm/kgh2o
—
8
23
93
636
1.61
3.70
1.2
1.2
3.58
1.25
u/ml
0.79
21
188
21
85
2.56
3.70
4.1
2.1
62.62
63.64
%
0.06
21
85
280
3103
0.63
3.67
5.4
5.5
6.29
6.11
mmol/l
1.05
254
2846
292
3205
0.62
3.66
29.0
15.8
—
—
—
0
0
276
3067
0.63
3.64
7.7
7.0
39.42
40.25
mmol/mol
0.60
259
2879
13
35
3.81
3.62
1.6
1.5
—
—
—
0
0
20
80
2.58
3.61
3.1
2.7
128.23
132.18
g/l
0.26
13
62
43
238
1.91
3.57
6.3
3.3
128.86
130.47
g/l
0.14
43
233
98
685
1.58
3.55
1.8
1.8
74074577.52
27210119.33
pmol/l
0.26
81
577
90
1251
0.63
3.53
2.7
3.3
0.61
0.77
ug/l
1.42
63
822
19
75
2.61
3.52
1.3
1.2
—
—
—
0
0
6
6
10.13
3.51
2.0
1.2
—
—
—
0
0
144
1099
1.50
3.48
3.6
3.8
2.34
2.34
mmol/l
0.11
127
992
63
937
0.61
3.26
5.0
3.2
0.00
0.01
estimate
0.99
30
275
48
286
1.78
3.17
5.2
3.2
7.42
7.42
ph
0.02
39
239
182
1475
1.45
3.16
14.4
12.3
0.01
0.00
e9/l
0.41
140
1203
97
1303
0.66
3.16
5.5
3.6
0.00
0.04
estimate
1.56
32
299
301
3258
0.63
3.07
45.6
21.6
3.97
4.01
mmol/l
2.02
295
3198
18
75
2.47
3.01
3.9
4.7
—
—
—
0
0
46
275
1.77
3.01
4.0
3.2
268.62
180.55
ng/l
0.53
39
249
301
3252
0.64
2.92
46.0
21.4
137.96
139.70
mmol/l
14.57
295
3195
253
2199
1.45
2.91
8.5
3.7
114.07
59.43
u/l
7.36
244
2080
61
398
1.63
2.91
13.9
10.0
118.92
121.24
g/l
0.34
61
391
10
27
3.77
2.90
1.1
1.0
—
—
—
0
0
9
22
4.16
2.90
1.1
1.0
—
—
—
0
0
7
206
0.33
2.89
1.1
1.4
—
—
—
0
0
110
1411
0.69
2.72
2.0
2.0
1.34
1.37
mmol/l
0.16
92
1177
8
19
4.28
2.69
1.3
1.1
—
—
—
0
0
7
15
4.73
2.61
2.9
3.5
0.57
0.59
mmol/l
—
7
15
8
20
4.06
2.58
1.9
2.6
—
—
—
0
0
94
695
1.47
2.56
4.6
4.3
69.40
415.63
ng/l
3.20
85
583
14
56
2.56
2.56
1.0
1.2
—
—
—
0
0
282
2531
1.44
2.51
14.0
9.3
93.18
80.70
u/l
4.87
272
2398
236
2058
1.39
2.45
10.8
5.7
6.77
6.88
mmol/l
0.37
228
1973
65
449
1.54
2.44
1.5
1.5
—
—
—
0
0
96
724
1.44
2.34
2.0
1.6
1.75
1.40
mg/l
0.34
77
584
11
41
2.73
2.22
2.4
2.7
3.49
1.30
g/24h
—
5
27
30
176
1.76
2.13
16.6
4.2
36.96
36.89
°c
1.03
30
176
35
215
1.69
2.12
1.2
1.2
—
—
—
0
0
16
75
2.18
2.11
1.5
1.2
—
—
—
0
0
70
933
0.69
2.04
1.5
1.4
—
—
—
0
0
180
1549
1.31
1.83
3.6
2.9
—
—
estimate
—
0
0
27
162
1.72
1.80
1.3
1.2
—
—
—
0
0
33
211
1.62
1.75
5.3
3.3
—
—
—
0
0
8
30
2.70
1.73
1.3
3.6
—
—
—
0
0
36
238
1.57
1.67
14.4
11.4
15.62
15.83
%
0.17
36
229
18
98
1.88
1.64
3.8
5.5
7.42
7.41
ph
0.07
18
98
5
14
3.60
1.62
1.0
1.5
—
—
—
0
0
8
32
2.53
1.60
1.4
3.7
1056.00
1302.31
mg
—
8
32
119
984
1.30
1.58
3.1
3.0
373.51
361.31
umol/l
0.49
101
869
5
15
3.36
1.53
1.2
2.2
2106.80
1074.53
u/ml
—
5
15
9
38
2.40
1.46
1.6
1.1
—
—
—
0
0
46
331
1.44
1.46
2.2
2.4
5.03
9.21
ug/l
1.47
40
297
5
16
3.15
1.44
1.0
1.7
56.40
47.82
%
—
5
11
13
68
1.94
1.35
3.4
6.2
7.79
8.24
kpa
0.58
13
68
13
68
1.94
1.35
3.4
6.2
4.70
5.01
kpa
1.00
13
68
13
68
1.94
1.35
2.2
1.3
—
—
—
0
0
25
161
1.59
1.32
3.4
3.6
24.69
25.21
mmol/l
0.46
25
147
35
244
1.48
1.31
4.2
4.3
1.19
1.22
mmol/l
1.80
28
216
13
69
1.92
1.30
2.2
1.3
—
—
—
0
0
34
473
0.69
1.25
3.2
2.3
13.14
13.74
nmol/l
0.14
29
418
8
36
2.25
1.25
1.3
1.1
—
—
—
0
0
11
56
1.99
1.23
2.1
1.3
—
—
—
0
0
13
71
1.86
1.21
2.2
1.3
—
—
—
0
0
13
71
1.86
1.21
2.2
1.3
—
—
—
0
0
238
2187
1.24
1.20
5.3
4.3
—
2.71
—
0
5
14
79
1.80
1.18
1.5
1.4
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
164.62
—
0
33
17
103
1.68
1.14
1.3
1.2
—
3.00
—
0
6
41
311
1.36
1.00
3.2
5.1
1.20
0.53
%
0.92
20
114
17
108
1.60
0.98
2.3
2.4
1.70
10.70
iu/ml
—
5
29
63
767
0.79
0.97
4.9
3.8
1.02
1.02
kg/l
2.86
44
517
40
304
1.35
0.97
4.9
4.4
7.32
7.34
ph
0.09
34
219
41
314
1.34
0.95
3.9
5.6
2.44
0.10
%
0.45
16
97
298
3111
0.80
0.95
38.9
17.8
31.78
26.39
mg/l
1.96
277
2624
12
70
1.74
0.93
2.3
1.3
—
—
—
0
0
6
28
2.16
0.92
6.3
3.6
1.00
0.93
index
—
6
28
6
30
2.02
0.87
1.3
1.3
—
—
—
0
0
6
30
2.02
0.87
2.7
1.6
—
—
—
0
0
21
145
1.47
0.87
1.4
1.7
—
—
—
0
0
10
166
0.59
0.85
1.3
1.8
37.30
41.28
nmol/l
—
10
156
40
311
1.32
0.85
3.5
5.2
0.06
0.14
%
0.52
16
107
32
241
1.36
0.84
9.0
5.0
—
—
—
0
0
6
32
1.89
0.82
1.3
1.3
0.20
0.17
nmol/l
—
6
23
0
25
0.00
0.79
0.0
1.2
—
97.32
—
0
25
220
2342
0.86
0.77
4.7
4.5
—
11224.22
—
0
9
6
34
1.78
0.76
1.0
1.1
—
—
—
0
0
23
168
1.39
0.73
8.2
3.7
26.26
25.04
mmol/l
0.76
23
161
32
247
1.32
0.73
4.2
3.6
—
—
—
0
0
10
60
1.68
0.72
1.6
3.2
—
—
—
0
0
7
40
1.76
0.71
2.0
1.7
10.90
11.09
%
—
7
40
41
331
1.27
0.68
3.4
5.1
1.00
0.88
%
0.14
17
128
5
27
1.86
0.68
1.4
1.3
—
—
nmol/l
—
0
0
28
360
0.76
0.68
1.5
1.5
—
—
—
0
0
11
71
1.57
0.62
1.6
1.5
157.83
169.71
au/ml
—
6
21
8
49
1.65
0.62
1.5
4.8
—
—
—
0
0
148
1359
1.15
0.62
4.1
3.4
6.40
6.14
ph
1.41
57
790
9
138
0.64
0.62
1.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.7
—
—
—
0
0
20
149
1.36
0.59
3.3
2.3
—
—
—
0
0
5
89
0.56
0.56
8.0
4.1
—
—
—
0
0
6
100
0.59
0.52
2.7
1.3
0.94
0.88
g/l
—
6
100
7
47
1.50
0.48
1.1
1.2
—
—
—
0
0
128
1185
1.12
0.46
3.3
3.3
2681.26
1311.89
ng/l
0.97
115
1017
42
360
1.19
0.44
1.6
1.4
—
—
—
0
0
47
407
1.18
0.44
1.4
1.3
—
—
—
0
0
9
130
0.68
0.44
1.1
1.8
209.00
214.41
pmol/l
—
9
121
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
8
61
1.32
0.39
1.1
1.6
—
—
—
0
0
8
61
1.32
0.39
1.1
1.6
—
—
—
0
0
8
61
1.32
0.39
1.1
1.6
—
—
—
0
0
8
61
1.32
0.39
1.1
1.6
—
—
—
0
0
5
35
1.43
0.39
1.4
1.2
—
—
—
0
0
5
36
1.39
0.38
2.4
1.7
78.00
60.29
%
—
5
31
12
90
1.34
0.36
1.2
1.1
—
—
—
0
0
14
108
1.31
0.36
2.0
1.6
—
11.07
—
0
19
16
200
0.79
0.35
1.3
1.3
611.79
286.65
u/ml
0.53
16
184
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
54
483
1.14
0.35
1.4
1.3
3.99
13.29
u/ml
1.25
11
163
66
722
0.90
0.32
4.1
5.5
—
—
—
0
0
19
157
1.22
0.30
1.3
1.2
—
—
—
0
0
276
2825
0.92
0.30
5.4
4.7
2.04
1.99
mu/l
0.29
263
2566
7
56
1.25
0.29
3.9
2.1
9.81
10.51
mmol/l
—
7
56
33
289
1.16
0.29
1.2
1.4
—
—
—
0
0
57
521
1.11
0.27
1.3
1.3
31.91
30.23
iu/ml
0.05
16
156
12
95
1.27
0.26
1.1
1.3
—
—
—
0
0
15
123
1.23
0.25
4.0
4.1
215.29
289.33
mg/l
—
7
60
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
7
95
0.73
0.22
4.7
2.2
15.80
13.16
mg/l
—
7
89
14
167
0.83
0.22
3.4
6.1
0.75
0.85
%
0.51
14
158
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
4.00
—
0
10
0
10
0.00
0.21
0.0
1.2
—
0.30
—
0
10
8
105
0.76
0.21
3.1
8.2
1.61
1.39
mmol/l
—
8
93
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
6
48
1.25
0.20
1.8
3.1
4.41
5.00
e9/l
—
6
48
122
1271
0.94
0.20
4.5
4.1
9.87
8.60
mg/mmol
0.20
77
831
175
1698
1.06
0.19
4.5
3.7
0.00
0.00
estimate
-0.00
36
348
177
1719
1.06
0.18
4.5
3.7
70.35
0.01
estimate
0.79
40
351
14
162
0.86
0.16
1.1
1.1
—
—
—
0
0
34
312
1.10
0.16
2.7
2.1
0.00
0.05
estimate
—
7
57
230
2255
1.05
0.16
3.8
3.8
14.73
14.84
pmol/l
0.26
217
2040
178
1736
1.05
0.15
4.6
3.7
0.00
0.02
estimate
0.79
36
322
19
172
1.11
0.11
3.4
2.3
0.00
5.34
estimate
—
5
47
18
197
0.91
0.10
1.2
1.2
—
—
—
0
0
5
46
1.09
0.09
1.8
1.3
—
—
—
0
0
7
66
1.06
0.08
5.0
3.0
—
—
—
0
0
7
68
1.03
0.08
2.0
2.9
60.57
58.75
%
—
7
68
130
1276
1.03
0.07
3.7
3.4
6.66
8.46
mmol/l
5.65
111
1077
43
447
0.96
0.06
2.6
3.0
4.20
6.01
e9/l
0.76
38
385
122
1241
0.98
0.06
3.8
3.5
80.85
55.66
mg/l
0.60
81
845
16
151
1.06
0.03
1.1
1.2
241.06
126.29
u/ml
—
5
54
142
1406
1.02
0.03
5.2
4.1
23.96
48.80
ng/l
3.08
122
1081
95
963
0.98
0.03
5.2
3.7
0.00
0.02
estimate
0.78
34
309
124
1231
1.01
0.01
2.3
2.2
—
—
—
0
0
44
446
0.98
0.00
1.5
1.3
—
—
—
0
0
14
143
0.98
0.00
1.6
1.9
—
—
—
0
0
19
185
1.03
0.00
2.4
2.6
—
—
—
0
0
36
365
0.98
0.00
1.9
2.4
123.81
119.34
ug/g
0.06
27
308
10
104
0.96
0.00
22.2
12.5
—
—
—
0
0
24
244
0.98
0.00
22.8
7.3
26.28
24.31
mmol/l
1.83
24
233
18
184
0.98
0.00
4.7
5.8
1.47
1.60
%
0.34
18
174
0
9
0.00
-0.00
0.0
1.6
—
30.67
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
22.69
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.4
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
7.20
—
0
6

Mortality – FinRegistry

Association

Association between endpoint G6_ALCOPOLY and mortality.

Females

Parameter HR [95% CI] p-value
G6_ALCOPOLY 6.471 [5.09, 8.24] < 0.001
Birth year 0.995 [0.99, 1.0] 0.275

During the follow-up period (1.1.1998 — 31.12.2019), 255 out of 596 females with G6_ALCOPOLY died.

Males

Parameter HR [95% CI] p-value
G6_ALCOPOLY 5.295 [4.65, 6.04] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1346 out of 2491 males with G6_ALCOPOLY died.

Mortality risk

Mortality risk for people of age

years, who have G6_ALCOPOLY.

N-year risk Females Males
1 0.432% 0.871%
5 3.556% 5.907%
10 9.79% 13.436%
15 17.855% 24.306%
20 29.641% 37.061%

Relationships between endpoints

Index endpoint: G6_ALCOPOLY – Alcohol induced polyneuropathy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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